Total number of protein in "GO:0007006" GO term: 68
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACAA2 | ACAA2 | P42765 | 3-ketoacyl-CoA thiolase, mitochondrial | chr18 | GO:0007006 | Not Cancer Driver | No | 42 | 0.106 | 51 | 2 | 0.039 | 0 |
| ALKBH7 | ALKBH7 | Q9BT30 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial | chr19 | GO:0007006 | Not Cancer Driver | No | 21 | 0.095 | 28 | 1 | 0.036 | 0 |
| AP3B1 | AP3B1 | O00203 | AP-3 complex subunit beta-1 | chr5 | GO:0007006 | Not Cancer Driver | No | 126 | 0.115 | 316 | 31 | 0.098 | 1 |
| ARHGAP11B | ARHGAP11B | Q3KRB8 | Inactive Rho GTPase-activating protein 11B | chr15 | GO:0007006 | Not Cancer Driver | No | 20 | 0.075 | 17 | 1 | 0.059 | 0 |
| ATF2 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0007006 | Not Cancer Driver | No | 65 | 0.129 | 451 | 58 | 0.129 | 0 |
| ATP5IF1 | ATP5IF1 | Q9UII2 | ATPase inhibitor, mitochondrial | chr1 | GO:0007006 | Not Cancer Driver | No | 8 | 0.075 | 85 | 7 | 0.082 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0007006 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BBC3 | BBC3 | Q96PG8 | Bcl-2-binding component 3, isoforms 3/4 | chr19 | GO:0007006 | Not Cancer Driver | No | 20 | 0.077 | 253 | 20 | 0.079 | 0 |
| BCL2L11 | BCL2L11 | O43521 | Bcl-2-like protein 11 | chr2 | GO:0007006 | Not Cancer Driver | No | 42 | 0.212 | 130 | 17 | 0.131 | 0 |
| BCL2L2 | BCL2L2 | Q92843 | Bcl-2-like protein 2 | chr14 | GO:0007006 | Not Cancer Driver | No | 22 | 0.114 | 34 | 6 | 0.176 | 0 |
| BCS1L | BCS1L | Q9Y276 | Mitochondrial chaperone BCS1 | chr2 | GO:0007006 | Not Cancer Driver | No | 35 | 0.084 | 5 | 0 | 0.0 | 21 |
| BID_ENST00000551952 | BID | P55957 | BH3-interacting domain death agonist | chr22 | GO:0007006 | Not Cancer Driver | No | 23 | 0.118 | 74 | 9 | 0.122 | 0 |
| BLOC1S2 | BLOC1S2 | Q6QNY1 | Biogenesis of lysosome-related organelles complex 1 subunit 2 | chr10 | GO:0007006 | Not Cancer Driver | No | 17 | 0.12 | 34 | 6 | 0.176 | 0 |
| BNIP3L | BNIP3L | O60238 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like | chr8 | GO:0007006 | Not Cancer Driver | No | 16 | 0.073 | 175 | 14 | 0.08 | 0 |
| BOK | BOK | Q9UMX3 | Bcl-2-related ovarian killer protein | chr2 | GO:0007006 | Not Cancer Driver | No | 7 | 0.033 | 0 | 0 | 0.0 | 0 |
| CALM3_ENST00000596362 | CALM3 | P0DP25 | Calmodulin-3 | chr19 | GO:0007006 | Not Cancer Driver | No | 17 | 0.114 | 115 | 10 | 0.087 | 3 |
| CAMK2A_ENST00000348628 | CAMK2A | Q9UQM7 | Calcium/calmodulin-dependent protein kinase type II subunit alpha | chr5 | GO:0007006 | Not Cancer Driver | No | 83 | 0.174 | 62 | 10 | 0.161 | 7 |
| CHCHD10_ENST00000484558 | CHCHD10 | Q8WYQ3 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial | chr22 | GO:0007006 | Not Cancer Driver | No | 8 | 0.056 | 97 | 4 | 0.041 | 4 |
| CLN8 | CLN8 | Q9UBY8 | Protein CLN8 | chr8 | GO:0007006 | Not Cancer Driver | No | 45 | 0.157 | 16 | 2 | 0.125 | 16 |
| COX18_ENST00000295890 | COX18 | Q8N8Q8 | Cytochrome c oxidase assembly protein COX18, mitochondrial | chr4 | GO:0007006 | Not Cancer Driver | No | 21 | 0.063 | 0 | 0 | 0.0 | 0 |
| EYA2 | EYA2 | O00167 | Eyes absent homolog 2 | chr20 | GO:0007006 | Not Cancer Driver | No | 107 | 0.199 | 204 | 50 | 0.245 | 0 |
| FZD9 | FZD9 | O00144 | Frizzled-9 | chr7 | GO:0007006 | Not Cancer Driver | No | 55 | 0.093 | 61 | 0 | 0.0 | 0 |
| GCLC | GCLC | P48506 | Glutamate--cysteine ligase catalytic subunit | chr6 | GO:0007006 | Not Cancer Driver | No | 73 | 0.115 | 167 | 18 | 0.108 | 3 |
| GSK3A | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | GO:0007006 | Not Cancer Driver | No | 55 | 0.114 | 180 | 8 | 0.044 | 0 |
| GSK3B_ENST00000264235 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0007006 | Not Cancer Driver | No | 56 | 0.133 | 146 | 13 | 0.089 | 0 |
| GZMB | GZMB | P10144 | Granzyme B | chr14 | GO:0007006 | Not Cancer Driver | No | 49 | 0.198 | 103 | 23 | 0.223 | 0 |
| HEBP2 | HEBP2 | Q9Y5Z4 | Heme-binding protein 2 | chr6 | GO:0007006 | Not Cancer Driver | No | 20 | 0.098 | 113 | 12 | 0.106 | 0 |
| HIP1R | HIP1R | O75146 | Huntingtin-interacting protein 1-related protein | chr12 | GO:0007006 | Not Cancer Driver | No | 94 | 0.088 | 524 | 34 | 0.065 | 0 |
| HK2 | HK2 | P52789 | Hexokinase-2 | chr2 | GO:0007006 | Not Cancer Driver | No | 138 | 0.15 | 77 | 7 | 0.091 | 0 |
| HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | GO:0007006 | Census, Compendium | Yes | 106 | 0.145 | 257 | 37 | 0.144 | 0 |
| HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | GO:0007006 | Not Cancer Driver | No | 24 | 0.037 | 200 | 13 | 0.065 | 0 |
| HSPA4 | HSPA4 | P34932 | Heat shock 70 kDa protein 4 | chr5 | GO:0007006 | Not Cancer Driver | No | 80 | 0.095 | 351 | 24 | 0.068 | 0 |
| MAIP1 | MAIP1 | Q8WWC4 | m-AAA protease-interacting protein 1, mitochondrial | chr2 | GO:0007006 | Not Cancer Driver | No | 28 | 0.096 | 12 | 0 | 0.0 | 0 |
| MAPK8_ENST00000374189 | MAPK8 | P45983 | Mitogen-activated protein kinase 8 | chr10 | GO:0007006 | Not Cancer Driver | No | 64 | 0.15 | 94 | 9 | 0.096 | 0 |
| MFN1 | MFN1 | Q8IWA4 | Mitofusin-1 | chr3 | GO:0007006 | Not Cancer Driver | No | 90 | 0.121 | 64 | 5 | 0.078 | 0 |
| MFN2_ENST00000444836 | MFN2 | O95140 | Mitofusin-2 | chr1 | GO:0007006 | Not Cancer Driver | No | 80 | 0.106 | 81 | 9 | 0.111 | 20 |
| MOAP1_ENST00000298894 | MOAP1 | Q96BY2 | Modulator of apoptosis 1 | chr14 | GO:0007006 | Not Cancer Driver | No | 48 | 0.137 | 47 | 8 | 0.17 | 0 |
| MPV17L | MPV17L | Q2QL34 | Mpv17-like protein | chr16 | GO:0007006 | Not Cancer Driver | No | 16 | 0.082 | 3 | 0 | 0.0 | 0 |
| MTRNR2L5 | MTRNR2L5 | P0CJ72 | Humanin-like 5 | chr10 | GO:0007006 | Not Cancer Driver | No | 1 | 0.042 | 0 | 0 | 0.0 | 0 |
| MUL1 | MUL1 | Q969V5 | Mitochondrial ubiquitin ligase activator of NFKB 1 | chr1 | GO:0007006 | Not Cancer Driver | No | 48 | 0.136 | 16 | 2 | 0.125 | 0 |
| NAIF1 | NAIF1 | Q69YI7 | Nuclear apoptosis-inducing factor 1 | chr9 | GO:0007006 | Not Cancer Driver | No | 46 | 0.141 | 219 | 27 | 0.123 | 0 |
| NMT1_ENST00000258960 | NMT1 | P30419 | Glycylpeptide N-tetradecanoyltransferase 1 | chr17 | GO:0007006 | Not Cancer Driver | No | 62 | 0.125 | 169 | 22 | 0.13 | 0 |
| NOL3_ENST00000268605 | NOL3 | O60936 | Nucleolar protein 3 | chr16 | GO:0007006 | Not Cancer Driver | No | 20 | 0.096 | 179 | 17 | 0.095 | 2 |
| OXA1L_ENST00000604262 | OXA1L | Q15070 | Mitochondrial inner membrane protein OXA1L | chr14 | GO:0007006 | Not Cancer Driver | No | 36 | 0.083 | 81 | 9 | 0.111 | 0 |
| PEX5_ENST00000420616 | PEX5 | P50542 | Peroxisomal targeting signal 1 receptor | chr12 | GO:0007006 | Not Cancer Driver | No | 73 | 0.114 | 321 | 36 | 0.112 | 2 |
| PPIF | PPIF | P30405 | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | chr10 | GO:0007006 | Not Cancer Driver | No | 19 | 0.092 | 43 | 4 | 0.093 | 0 |
| RCC1L | RCC1L | Q96I51 | RCC1-like G exchanging factor-like protein | chr7 | GO:0007006 | Not Cancer Driver | No | 19 | 0.041 | 87 | 7 | 0.08 | 0 |
| RHOT1_ENST00000333942 | RHOT1 | Q8IXI2 | Mitochondrial Rho GTPase 1 | chr17 | GO:0007006 | Not Cancer Driver | No | 56 | 0.091 | 46 | 2 | 0.043 | 0 |
| RHOT2 | RHOT2 | Q8IXI1 | Mitochondrial Rho GTPase 2 | chr16 | GO:0007006 | Not Cancer Driver | No | 52 | 0.084 | 79 | 5 | 0.063 | 0 |
| RTL10_ENST00000407472 | RTL10 | Q7L3V2 | Protein Bop | chr22 | GO:0007006 | Not Cancer Driver | No | 52 | 0.143 | 196 | 31 | 0.158 | 0 |
| SAMM50 | SAMM50 | Q9Y512 | Sorting and assembly machinery component 50 homolog | chr22 | GO:0007006 | Not Cancer Driver | No | 51 | 0.109 | 34 | 1 | 0.029 | 0 |
| SLC25A31 | SLC25A31 | Q9H0C2 | ADP/ATP translocase 4 | chr4 | GO:0007006 | Not Cancer Driver | No | 68 | 0.216 | 8 | 0 | 0.0 | 0 |
| SLC25A4 | SLC25A4 | P12235 | ADP/ATP translocase 1 | chr4 | GO:0007006 | Not Cancer Driver | No | 24 | 0.081 | 0 | 0 | 0.0 | 9 |
| SLC25A5 | SLC25A5 | P05141 | ADP/ATP translocase 2 | chrX | GO:0007006 | Not Cancer Driver | No | 41 | 0.138 | 0 | 0 | 0.0 | 0 |
| SLC25A6 | SLC25A6 | P12236 | ADP/ATP translocase 3 | chrX | GO:0007006 | Not Cancer Driver | No | 41 | 0.138 | 0 | 0 | 0.0 | 0 |
| SLC35F6 | SLC35F6 | Q8N357 | Solute carrier family 35 member F6 | chr2 | GO:0007006 | Not Cancer Driver | No | 33 | 0.089 | 13 | 0 | 0.0 | 0 |
| SLC9A1 | SLC9A1 | P19634 | Sodium/hydrogen exchanger 1 | chr1 | GO:0007006 | Not Cancer Driver | No | 89 | 0.109 | 251 | 29 | 0.116 | 1 |
| SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0007006 | Not Cancer Driver | No | 21 | 0.15 | 107 | 13 | 0.121 | 5 |
| SPG7 | SPG7 | Q9UQ90 | Paraplegin | chr16 | GO:0007006 | Not Cancer Driver | No | 97 | 0.122 | 181 | 29 | 0.16 | 4 |
| STPG1 | STPG1 | Q5TH74 | O(6)-methylguanine-induced apoptosis 2 | chr1 | GO:0007006 | Not Cancer Driver | No | 45 | 0.135 | 171 | 23 | 0.135 | 0 |
| THEM4 | THEM4 | Q5T1C6 | Acyl-coenzyme A thioesterase THEM4 | chr1 | GO:0007006 | Not Cancer Driver | No | 19 | 0.079 | 14 | 0 | 0.0 | 0 |
| TIMM50_ENST00000607714 | TIMM50 | Q3ZCQ8 | Mitochondrial import inner membrane translocase subunit TIM50 | chr19 | GO:0007006 | Not Cancer Driver | No | 39 | 0.11 | 75 | 7 | 0.093 | 0 |
| TMEM102 | TMEM102 | Q8N9M5 | Transmembrane protein 102 | chr17 | GO:0007006 | Not Cancer Driver | No | 38 | 0.075 | 141 | 13 | 0.092 | 0 |
| TMEM14A | TMEM14A | Q9Y6G1 | Transmembrane protein 14A | chr6 | GO:0007006 | Not Cancer Driver | No | 10 | 0.101 | 0 | 0 | 0.0 | 0 |
| TOMM22 | TOMM22 | Q9NS69 | Mitochondrial import receptor subunit TOM22 homolog | chr22 | GO:0007006 | Not Cancer Driver | No | 18 | 0.127 | 83 | 9 | 0.108 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0007006 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| VDAC2_ENST00000543351 | VDAC2 | P45880 | Voltage-dependent anion-selective channel protein 2 | chr10 | GO:0007006 | Not Cancer Driver | No | 35 | 0.119 | 9 | 1 | 0.111 | 0 |
| ZNF205_ENST00000382192 | ZNF205 | O95201 | Zinc finger protein 205 | chr16 | GO:0007006 | Not Cancer Driver | No | 74 | 0.134 | 367 | 49 | 0.134 | 0 |