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Total number of protein in "GO:0006959" GO term:  122

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AC136428.1 IGHV3OR16-17 S4R3C0 Immunoglobulin heavy variable 3/OR16-17 (non-functional) (Fragment) chr16 GO:0006959 Not Cancer Driver No 42 0.362 0 0 0.0 0
AIRE AIRE O43918 Autoimmune regulator chr21 GO:0006959 Not Cancer Driver No 71 0.13 338 48 0.142 19
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0006959 Not Cancer Driver No 129 0.191 16 2 0.125 0
APCS APCS P02743 Serum amyloid P-component chr1 GO:0006959 Not Cancer Driver No 73 0.327 0 0 0.0 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0006959 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0006959 Census Yes 44 0.097 259 23 0.089 0
BLNK BLNK Q8WV28 B-cell linker protein chr10 GO:0006959 Not Cancer Driver No 74 0.162 376 61 0.162 0
BST1 BST1 Q10588 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 chr4 GO:0006959 Not Cancer Driver No 40 0.126 11 0 0.0 0
C1QA C1QA P02745 Complement C1q subcomponent subunit A chr1 GO:0006959 Not Cancer Driver No 41 0.167 124 16 0.129 0
C1QB C1QB P02746 Complement C1q subcomponent subunit B chr1 GO:0006959 Not Cancer Driver No 46 0.182 133 31 0.233 1
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0006959 Not Cancer Driver No 14 0.05 103 6 0.058 2
C1QC C1QC P02747 Complement C1q subcomponent subunit C chr1 GO:0006959 Not Cancer Driver No 46 0.188 134 26 0.194 1
C1R C1R P00736 Complement C1r subcomponent chr12 GO:0006959 Not Cancer Driver No 88 0.125 51 6 0.118 6
C1RL C1RL Q9NZP8 Complement C1r subcomponent-like protein chr12 GO:0006959 Not Cancer Driver No 60 0.123 146 22 0.151 0
C1S C1S P09871 Complement C1s subcomponent chr12 GO:0006959 Not Cancer Driver No 128 0.186 97 21 0.216 1
C2 C2 P06681 Complement C2 chr6 GO:0006959 Not Cancer Driver No 120 0.16 120 17 0.142 3
C3 C3 P01024 Complement C3 chr19 GO:0006959 Not Cancer Driver No 337 0.203 287 50 0.174 12
C4A C4A P0C0L4 Complement C4-A chr6 GO:0006959 Not Cancer Driver No 43 0.025 309 6 0.019 0
C4BPA C4BPA P04003 C4b-binding protein alpha chain chr1 GO:0006959 Not Cancer Driver No 109 0.183 40 10 0.25 0
C4BPB C4BPB P20851 C4b-binding protein beta chain chr1 GO:0006959 Not Cancer Driver No 40 0.159 0 0 0.0 0
C5 C5 P01031 Complement C5 chr9 GO:0006959 Not Cancer Driver No 192 0.115 84 9 0.107 0
C6 C6 P13671 Complement component C6 chr5 GO:0006959 Not Cancer Driver No 346 0.37 121 47 0.388 0
C7 C7 P10643 Complement component C7 chr5 GO:0006959 Not Cancer Driver No 291 0.345 89 37 0.416 5
C8A C8A P07357 Complement component C8 alpha chain chr1 GO:0006959 Not Cancer Driver No 176 0.301 25 9 0.36 0
C8B C8B P07358 Complement component C8 beta chain chr1 GO:0006959 Not Cancer Driver No 186 0.315 29 11 0.379 0
C8G C8G P07360 Complement component C8 gamma chain chr9 GO:0006959 Not Cancer Driver No 10 0.05 26 2 0.077 0
C9 C9 P02748 Complement component C9 chr5 GO:0006959 Not Cancer Driver No 156 0.279 40 8 0.2 2
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0006959 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0006959 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0006959 Not Cancer Driver No 56 0.15 13 2 0.154 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0006959 Census Yes 42 0.191 18 10 0.556 0
CD46_ENST00000358170 CD46 P15529 Membrane cofactor protein chr1 GO:0006959 Not Cancer Driver No 53 0.135 52 4 0.077 5
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 GO:0006959 Not Cancer Driver No 45 0.118 128 13 0.102 1
CD81 CD81 P60033 CD81 antigen chr11 GO:0006959 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD83 CD83 Q01151 CD83 antigen chr6 GO:0006959 Not Cancer Driver No 24 0.117 48 8 0.167 0
CFB CFB P00751 Complement factor B chr6 GO:0006959 Not Cancer Driver No 75 0.098 112 20 0.179 7
CFD_ENST00000327726 CFD P00746 Complement factor D chr19 GO:0006959 Not Cancer Driver No 6 0.024 69 3 0.043 2
CFH CFH P08603 Complement factor H chr1 GO:0006959 Not Cancer Driver No 355 0.288 89 28 0.315 42
CFHR5 CFHR5 Q9BXR6 Complement factor H-related protein 5 chr1 GO:0006959 Not Cancer Driver No 162 0.285 40 9 0.225 0
CFI_ENST00000394634 CFI P05156 Complement factor I chr4 GO:0006959 Not Cancer Driver No 97 0.166 4 0 0.0 13
CFP CFP P27918 Properdin chrX GO:0006959 Not Cancer Driver No 60 0.128 48 7 0.146 6
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0006959 Not Cancer Driver No 69 0.154 156 27 0.173 0
COLEC10 COLEC10 Q9Y6Z7 Collectin-10 chr8 GO:0006959 Not Cancer Driver No 58 0.209 95 23 0.242 1
COLEC11_ENST00000349077 COLEC11 Q9BWP8 Collectin-11 chr2 GO:0006959 Not Cancer Driver No 72 0.266 158 40 0.253 2
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0006959 Compendium Yes 383 0.188 151 42 0.278 0
CR2_ENST00000367058 CR2 P20023 Complement receptor type 2 chr1 GO:0006959 Not Cancer Driver No 273 0.264 85 28 0.329 0
CRP CRP P02741 C-reactive protein chr1 GO:0006959 Not Cancer Driver No 59 0.263 0 0 0.0 0
DEFA4 DEFA4 P12838 Defensin alpha 4 chr8 GO:0006959 Not Cancer Driver No 35 0.361 17 5 0.294 0
DMBT1_ENST00000619379 DMBT1 Q9UGM3 Deleted in malignant brain tumors 1 protein chr10 GO:0006959 Not Cancer Driver No 506 0.21 404 64 0.158 0
EBI3 EBI3 Q14213 Interleukin-27 subunit beta chr19 GO:0006959 Not Cancer Driver No 32 0.14 10 1 0.1 0
EXO1_ENST00000348581 EXO1 Q9UQ84 Exonuclease 1 chr1 GO:0006959 Not Cancer Driver No 123 0.145 472 76 0.161 0
FAM3A_ENST00000447601 FAM3A P98173 Protein FAM3A chrX GO:0006959 Not Cancer Driver No 27 0.117 48 9 0.188 0
FCN1 FCN1 O00602 Ficolin-1 chr9 GO:0006959 Not Cancer Driver No 107 0.328 88 15 0.17 0
FCN2 FCN2 Q15485 Ficolin-2 chr9 GO:0006959 Not Cancer Driver No 73 0.233 80 19 0.237 0
FCN3 FCN3 O75636 Ficolin-3 chr1 GO:0006959 Not Cancer Driver No 46 0.154 65 19 0.292 0
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0006959 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0006959 Not Cancer Driver No 89 0.181 143 29 0.203 7
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0006959 Not Cancer Driver No 25 0.059 279 18 0.065 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0006959 Census, Compendium Yes 111 0.251 364 87 0.239 2
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 GO:0006959 Not Cancer Driver No 77 0.138 73 11 0.151 24
GPR183 GPR183 P32249 G-protein coupled receptor 183 chr13 GO:0006959 Not Cancer Driver No 53 0.147 25 3 0.12 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0006959 Not Cancer Driver No 48 0.18 12 1 0.083 0
IFNA10 IFNA10 P01566 Interferon alpha-10 chr9 GO:0006959 Not Cancer Driver No 40 0.212 1 0 0.0 0
IFNA13_ENST00000449498 IFNA13 P01562 Interferon alpha-1/13 chr9 GO:0006959 Not Cancer Driver No 39 0.206 2 0 0.0 0
IFNA14 IFNA14 P01570 Interferon alpha-14 chr9 GO:0006959 Not Cancer Driver No 39 0.206 1 1 1.0 0
IFNA16 IFNA16 P05015 Interferon alpha-16 chr9 GO:0006959 Not Cancer Driver No 61 0.323 1 0 0.0 0
IFNA17 IFNA17 P01571 Interferon alpha-17 chr9 GO:0006959 Not Cancer Driver No 37 0.196 0 0 0.0 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0006959 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNA21 IFNA21 P01568 Interferon alpha-21 chr9 GO:0006959 Not Cancer Driver No 34 0.18 0 0 0.0 0
IFNA4 IFNA4 P05014 Interferon alpha-4 chr9 GO:0006959 Not Cancer Driver No 39 0.206 1 0 0.0 0
IFNA5 IFNA5 P01569 Interferon alpha-5 chr9 GO:0006959 Not Cancer Driver No 36 0.19 1 0 0.0 0
IFNA6 IFNA6 P05013 Interferon alpha-6 chr9 GO:0006959 Not Cancer Driver No 28 0.148 4 0 0.0 0
IFNA7 IFNA7 P01567 Interferon alpha-7 chr9 GO:0006959 Not Cancer Driver No 43 0.228 1 1 1.0 0
IFNA8 IFNA8 P32881 Interferon alpha-8 chr9 GO:0006959 Not Cancer Driver No 43 0.228 0 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0006959 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNE IFNE Q86WN2 Interferon epsilon chr9 GO:0006959 Not Cancer Driver No 30 0.144 17 4 0.235 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0006959 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNK IFNK Q9P0W0 Interferon kappa chr9 GO:0006959 Not Cancer Driver No 17 0.082 23 0 0.0 0
IFNW1 IFNW1 P05000 Interferon omega-1 chr9 GO:0006959 Not Cancer Driver No 32 0.164 10 3 0.3 0
IGHD IGHD P01880 Immunoglobulin heavy constant delta chr14 GO:0006959 Not Cancer Driver No 61 0.159 245 40 0.163 0
IGLL1 IGLL1 P15814 Immunoglobulin lambda-like polypeptide 1 chr22 GO:0006959 Not Cancer Driver No 25 0.117 144 18 0.125 1
IGLL5 IGLL5 B9A064 Immunoglobulin lambda-like polypeptide 5 chr22 GO:0006959 Not Cancer Driver No 59 0.276 127 35 0.276 0
IL36RN_ENST00000346807 IL36RN Q9UBH0 Interleukin-36 receptor antagonist protein chr2 GO:0006959 Not Cancer Driver No 34 0.219 7 4 0.571 4
IL6 IL6 P05231 Interleukin-6 chr7 GO:0006959 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL7 IL7 P13232 Interleukin-7 chr8 GO:0006959 Not Cancer Driver No 29 0.164 19 4 0.211 0
JCHAIN JCHAIN P01591 Immunoglobulin J chain chr4 GO:0006959 Not Cancer Driver No 37 0.233 9 3 0.333 0
KRT1 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 GO:0006959 Not Cancer Driver No 133 0.207 426 98 0.23 20
LTA LTA P01374 Lymphotoxin-alpha chr6 GO:0006959 Not Cancer Driver No 37 0.18 20 5 0.25 0
LTF LTF P02788 Lactotransferrin chr3 GO:0006959 Not Cancer Driver No 131 0.185 21 4 0.19 0
MASP1_ENST00000337774 MASP1 P48740 Mannan-binding lectin serine protease 1 chr3 GO:0006959 Not Cancer Driver No 142 0.203 72 14 0.194 0
MASP2 MASP2 O00187 Mannan-binding lectin serine protease 2 chr1 GO:0006959 Not Cancer Driver No 99 0.144 58 11 0.19 2
MBL2 MBL2 P11226 Mannose-binding protein C chr10 GO:0006959 Not Cancer Driver No 63 0.254 122 32 0.262 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0006959 Not Cancer Driver No 92 0.195 408 81 0.199 0
MFAP4_ENST00000299610 MFAP4 P55083 Microfibril-associated glycoprotein 4 chr17 GO:0006959 Not Cancer Driver No 35 0.137 0 0 0.0 0
MS4A1_ENST00000345732 MS4A1 P11836 B-lymphocyte antigen CD20 chr11 GO:0006959 Not Cancer Driver No 73 0.246 83 23 0.277 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0006959 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0006959 Census, Compendium Yes 282 0.114 630 77 0.122 1
PAX5 PAX5 Q02548 Paired box protein Pax-5 chr9 GO:0006959 Census Yes 83 0.212 291 62 0.213 1
PDCD1 PDCD1 Q15116 Programmed cell death protein 1 chr2 GO:0006959 Not Cancer Driver No 56 0.194 141 37 0.262 0
POU2AF1 POU2AF1 Q16633 POU domain class 2-associating factor 1 chr11 GO:0006959 Census Yes 59 0.23 181 45 0.249 0
POU2F2 POU2F2 P09086 POU domain, class 2, transcription factor 2 chr19 GO:0006959 Compendium Yes 82 0.171 387 67 0.173 0
PSMB10 PSMB10 P40306 Proteasome subunit beta type-10 chr16 GO:0006959 Not Cancer Driver No 22 0.081 36 5 0.139 0
RARRES2 RARRES2 Q99969 Retinoic acid receptor responder protein 2 chr7 GO:0006959 Not Cancer Driver No 16 0.098 14 2 0.143 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0006959 Not Cancer Driver No 49 0.098 151 19 0.126 2
RNASE2 RNASE2 P10153 Non-secretory ribonuclease chr14 GO:0006959 Not Cancer Driver No 30 0.186 20 4 0.2 0
RNASE3 RNASE3 P12724 Eosinophil cationic protein chr14 GO:0006959 Not Cancer Driver No 37 0.231 8 0 0.0 0
SERPING1 SERPING1 P05155 Plasma protease C1 inhibitor chr11 GO:0006959 Not Cancer Driver No 74 0.148 113 13 0.115 40
SFTPD SFTPD P35247 Pulmonary surfactant-associated protein D chr10 GO:0006959 Not Cancer Driver No 66 0.176 274 53 0.193 0
SH2D1A SH2D1A O60880 SH2 domain-containing protein 1A chrX GO:0006959 Not Cancer Driver No 40 0.312 24 8 0.333 19
SPON2_ENST00000431380 SPON2 Q9BUD6 Spondin-2 chr4 GO:0006959 Not Cancer Driver No 36 0.109 73 4 0.055 0
ST6GAL1 ST6GAL1 P15907 Beta-galactoside alpha-2,6-sialyltransferase 1 chr3 GO:0006959 Not Cancer Driver No 55 0.135 34 8 0.235 0
SUSD4 SUSD4 Q5VX71 Sushi domain-containing protein 4 chr1 GO:0006959 Not Cancer Driver No 85 0.173 134 27 0.201 0
TFE3 TFE3 P19532 Transcription factor E3 chrX GO:0006959 Census Yes 92 0.16 524 84 0.16 0
TFEB_ENST00000403298 TFEB P19484 Transcription factor EB chr6 GO:0006959 Census Yes 58 0.122 429 47 0.11 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0006959 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF21 TNFRSF21 O75509 Tumor necrosis factor receptor superfamily member 21 chr6 GO:0006959 Not Cancer Driver No 98 0.15 280 46 0.164 0
TRAF3IP2_ENST00000392556 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 GO:0006959 Not Cancer Driver No 59 0.103 410 39 0.095 2
TREM1 TREM1 Q9NP99 Triggering receptor expressed on myeloid cells 1 chr6 GO:0006959 Not Cancer Driver No 45 0.192 63 7 0.111 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0006959 Not Cancer Driver No 43 0.187 27 2 0.074 1
VSIG4 VSIG4 Q9Y279 V-set and immunoglobulin domain-containing protein 4 chrX GO:0006959 Not Cancer Driver No 73 0.183 70 13 0.186 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0006959 Not Cancer Driver No 67 0.116 376 44 0.117 0
ZP3 ZP3 P21754 Zona pellucida sperm-binding protein 3 chr7 GO:0006959 Not Cancer Driver No 55 0.13 56 11 0.196 1