Total number of protein in "GO:0006303" GO term: 44
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| APLF | APLF | Q8IW19 | Aprataxin and PNK-like factor | chr2 | GO:0006303 | Not Cancer Driver | No | 64 | 0.125 | 407 | 57 | 0.14 | 0 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0006303 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| ATP23 | ATP23 | Q9Y6H3 | Mitochondrial inner membrane protease ATP23 homolog | chr12 | GO:0006303 | Not Cancer Driver | No | 26 | 0.106 | 25 | 3 | 0.12 | 0 |
| CYREN | CYREN | Q9BWK5 | Cell cycle regulator of non-homologous end joining | chr7 | GO:0006303 | Not Cancer Driver | No | 24 | 0.153 | 128 | 19 | 0.148 | 0 |
| DCLRE1A | DCLRE1A | Q6PJP8 | DNA cross-link repair 1A protein | chr10 | GO:0006303 | Not Cancer Driver | No | 92 | 0.088 | 514 | 45 | 0.088 | 0 |
| DCLRE1B | DCLRE1B | Q9H816 | 5' exonuclease Apollo | chr1 | GO:0006303 | Not Cancer Driver | No | 65 | 0.122 | 127 | 17 | 0.134 | 0 |
| DCLRE1C | DCLRE1C | Q96SD1 | Protein artemis | chr10 | GO:0006303 | Not Cancer Driver | No | 76 | 0.11 | 277 | 26 | 0.094 | 3 |
| DNTT | DNTT | P04053 | DNA nucleotidylexotransferase | chr10 | GO:0006303 | Not Cancer Driver | No | 106 | 0.208 | 66 | 16 | 0.242 | 0 |
| ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0006303 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
| ERCC4 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:0006303 | Census | Yes | 120 | 0.131 | 225 | 27 | 0.12 | 15 |
| ERCC6 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | GO:0006303 | Not Cancer Driver | No | 211 | 0.141 | 829 | 117 | 0.141 | 9 |
| ERCC8 | ERCC8 | Q13216 | DNA excision repair protein ERCC-8 | chr5 | GO:0006303 | Not Cancer Driver | No | 25 | 0.063 | 53 | 8 | 0.151 | 7 |
| HMCES_ENST00000502878 | HMCES | Q96FZ2 | Abasic site processing protein HMCES | chr3 | GO:0006303 | Not Cancer Driver | No | 37 | 0.105 | 131 | 16 | 0.122 | 0 |
| HMGB1_ENST00000405805 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:0006303 | Not Cancer Driver | No | 25 | 0.116 | 203 | 20 | 0.099 | 0 |
| HMGB2 | HMGB2 | P26583 | High mobility group protein B2 | chr4 | GO:0006303 | Not Cancer Driver | No | 38 | 0.182 | 207 | 38 | 0.184 | 0 |
| IFFO1_ENST00000396840 | IFFO1 | Q0D2I5 | Non-homologous end joining factor IFFO1 | chr12 | GO:0006303 | Not Cancer Driver | No | 59 | 0.106 | 363 | 33 | 0.091 | 0 |
| KDM2A | KDM2A | Q9Y2K7 | Lysine-specific demethylase 2A | chr11 | GO:0006303 | Not Cancer Driver | No | 131 | 0.113 | 387 | 48 | 0.124 | 0 |
| LIG3 | LIG3 | P49916 | DNA ligase 3 | chr17 | GO:0006303 | Not Cancer Driver | No | 125 | 0.124 | 280 | 36 | 0.129 | 0 |
| LIG4 | LIG4 | P49917 | DNA ligase 4 | chr13 | GO:0006303 | Not Cancer Driver | No | 134 | 0.147 | 63 | 10 | 0.159 | 2 |
| MLH1 | MLH1 | P40692 | DNA mismatch repair protein Mlh1 | chr3 | GO:0006303 | Census | Yes | 92 | 0.122 | 208 | 22 | 0.106 | 85 |
| MRE11 | MRE11 | P49959 | Double-strand break repair protein MRE11 | chr11 | GO:0006303 | Not Cancer Driver | No | 84 | 0.119 | 292 | 35 | 0.12 | 1 |
| NHEJ1 | NHEJ1 | Q9H9Q4 | Non-homologous end-joining factor 1 | chr2 | GO:0006303 | Not Cancer Driver | No | 35 | 0.117 | 83 | 8 | 0.096 | 2 |
| NSMCE2_ENST00000522563 | NSMCE2 | Q96MF7 | E3 SUMO-protein ligase NSE2 | chr8 | GO:0006303 | Not Cancer Driver | No | 30 | 0.121 | 119 | 12 | 0.101 | 0 |
| PAXX | PAXX | Q9BUH6 | Protein PAXX | chr9 | GO:0006303 | Not Cancer Driver | No | 22 | 0.108 | 121 | 17 | 0.14 | 0 |
| PNKP | PNKP | Q96T60 | Bifunctional polynucleotide phosphatase/kinase | chr19 | GO:0006303 | Not Cancer Driver | No | 53 | 0.102 | 177 | 23 | 0.13 | 4 |
| POLA1_ENST00000379059 | POLA1 | P09884 | DNA polymerase alpha catalytic subunit | chrX | GO:0006303 | Not Cancer Driver | No | 185 | 0.127 | 347 | 45 | 0.13 | 3 |
| POLB | POLB | P06746 | DNA polymerase beta | chr8 | GO:0006303 | Not Cancer Driver | No | 43 | 0.128 | 87 | 11 | 0.126 | 0 |
| POLL_ENST00000370169 | POLL | Q9UGP5 | DNA polymerase lambda | chr10 | GO:0006303 | Not Cancer Driver | No | 69 | 0.12 | 215 | 16 | 0.074 | 0 |
| POLM_ENST00000242248 | POLM | Q9NP87 | DNA-directed DNA/RNA polymerase mu | chr7 | GO:0006303 | Not Cancer Driver | No | 57 | 0.115 | 187 | 16 | 0.086 | 0 |
| POLQ | POLQ | O75417 | DNA polymerase theta | chr3 | GO:0006303 | Census, Compendium | Yes | 364 | 0.141 | 949 | 135 | 0.142 | 0 |
| PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0006303 | Not Cancer Driver | No | 538 | 0.13 | 421 | 61 | 0.145 | 2 |
| PRPF19 | PRPF19 | Q9UMS4 | Pre-mRNA-processing factor 19 | chr11 | GO:0006303 | Not Cancer Driver | No | 71 | 0.141 | 109 | 16 | 0.147 | 0 |
| PSMD14 | PSMD14 | O00487 | 26S proteasome non-ATPase regulatory subunit 14 | chr2 | GO:0006303 | Not Cancer Driver | No | 23 | 0.074 | 67 | 6 | 0.09 | 0 |
| RNF8 | RNF8 | O76064 | E3 ubiquitin-protein ligase RNF8 | chr6 | GO:0006303 | Not Cancer Driver | No | 56 | 0.115 | 226 | 29 | 0.128 | 0 |
| SETMAR | SETMAR | Q53H47 | Histone-lysine N-methyltransferase SETMAR | chr3 | GO:0006303 | Not Cancer Driver | No | 62 | 0.091 | 154 | 12 | 0.078 | 0 |
| SMARCAL1 | SMARCAL1 | Q9NZC9 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 | chr2 | GO:0006303 | Not Cancer Driver | No | 128 | 0.134 | 335 | 49 | 0.146 | 11 |
| SMC5 | SMC5 | Q8IY18 | Structural maintenance of chromosomes protein 5 | chr9 | GO:0006303 | Not Cancer Driver | No | 126 | 0.114 | 378 | 43 | 0.114 | 0 |
| TP53BP1_ENST00000263801 | TP53BP1 | Q12888 | TP53-binding protein 1 | chr15 | GO:0006303 | Not Cancer Driver | No | 227 | 0.115 | 1632 | 190 | 0.116 | 0 |
| UVRAG | UVRAG | Q9P2Y5 | UV radiation resistance-associated gene protein | chr11 | GO:0006303 | Not Cancer Driver | No | 89 | 0.127 | 243 | 28 | 0.115 | 0 |
| XRCC1 | XRCC1 | P18887 | DNA repair protein XRCC1 | chr19 | GO:0006303 | Not Cancer Driver | No | 85 | 0.134 | 426 | 53 | 0.124 | 1 |
| XRCC4 | XRCC4 | Q13426 | DNA repair protein XRCC4 | chr5 | GO:0006303 | Not Cancer Driver | No | 47 | 0.14 | 171 | 31 | 0.181 | 3 |
| XRCC5_ENST00000392132 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | GO:0006303 | Not Cancer Driver | No | 87 | 0.119 | 118 | 11 | 0.093 | 0 |
| XRCC6 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | GO:0006303 | Not Cancer Driver | No | 66 | 0.108 | 140 | 12 | 0.086 | 0 |
| ZBTB7A_ENST00000601588 | ZBTB7A | O95365 | Zinc finger and BTB domain-containing protein 7A | chr19 | GO:0006303 | Not Cancer Driver | No | 60 | 0.103 | 285 | 30 | 0.105 | 0 |