Total number of protein in "GO:0005884" GO term: 83
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACKR2 | ACKR2 | O00590 | Atypical chemokine receptor 2 | chr3 | GO:0005884 | Not Cancer Driver | No | 70 | 0.182 | 25 | 6 | 0.24 | 0 |
| ACTA1 | ACTA1 | P68133 | Actin, alpha skeletal muscle | chr1 | GO:0005884 | Not Cancer Driver | No | 70 | 0.186 | 48 | 14 | 0.292 | 84 |
| ACTBL2 | ACTBL2 | Q562R1 | Beta-actin-like protein 2 | chr5 | GO:0005884 | Not Cancer Driver | No | 73 | 0.194 | 29 | 5 | 0.172 | 0 |
| ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | GO:0005884 | Not Cancer Driver | No | 112 | 0.299 | 43 | 5 | 0.116 | 5 |
| ACTC1 | ACTC1 | P68032 | Actin, alpha cardiac muscle 1 | chr15 | GO:0005884 | Not Cancer Driver | No | 114 | 0.302 | 48 | 19 | 0.396 | 11 |
| ACTG1_ENST00000575087 | ACTG1 | P63261 | Actin, cytoplasmic 2 | chr17 | GO:0005884 | Not Cancer Driver | No | 73 | 0.195 | 42 | 10 | 0.238 | 16 |
| ACTN1_ENST00000193403 | ACTN1 | P12814 | Alpha-actinin-1 | chr14 | GO:0005884 | Not Cancer Driver | No | 108 | 0.121 | 195 | 30 | 0.154 | 6 |
| ACTN2_ENST00000366578 | ACTN2 | P35609 | Alpha-actinin-2 | chr1 | GO:0005884 | Not Cancer Driver | No | 227 | 0.254 | 131 | 29 | 0.221 | 9 |
| ACTN3_ENST00000513398 | ACTN3 | Q08043 | Alpha-actinin-3 | chr11 | GO:0005884 | Not Cancer Driver | No | 123 | 0.137 | 135 | 13 | 0.096 | 0 |
| AIF1 | AIF1 | P55008 | Allograft inflammatory factor 1 | chr6 | GO:0005884 | Not Cancer Driver | No | 14 | 0.095 | 61 | 6 | 0.098 | 0 |
| AIF1L_ENST00000247291 | AIF1L | Q9BQI0 | Allograft inflammatory factor 1-like | chr9 | GO:0005884 | Not Cancer Driver | No | 9 | 0.06 | 44 | 1 | 0.023 | 0 |
| AMOT | AMOT | Q4VCS5 | Angiomotin | chrX | GO:0005884 | Not Cancer Driver | No | 161 | 0.149 | 909 | 128 | 0.141 | 0 |
| ANXA1_ENST00000257497 | ANXA1 | P04083 | Annexin A1 | chr9 | GO:0005884 | Not Cancer Driver | No | 59 | 0.171 | 61 | 12 | 0.197 | 0 |
| APC2_ENST00000233607 | APC2 | O95996 | Adenomatous polyposis coli protein 2 | chr19 | GO:0005884 | Not Cancer Driver | No | 117 | 0.051 | 1725 | 78 | 0.045 | 0 |
| ARHGAP6 | ARHGAP6 | O43182 | Rho GTPase-activating protein 6 | chrX | GO:0005884 | Not Cancer Driver | No | 168 | 0.172 | 680 | 118 | 0.174 | 0 |
| AVIL | AVIL | O75366 | Advillin | chr12 | GO:0005884 | Not Cancer Driver | No | 91 | 0.111 | 138 | 17 | 0.123 | 2 |
| COBL_ENST00000265136 | COBL | O75128 | Protein cordon-bleu | chr7 | GO:0005884 | Not Cancer Driver | No | 233 | 0.185 | 1149 | 216 | 0.188 | 0 |
| CORO1A | CORO1A | P31146 | Coronin-1A | chr16 | GO:0005884 | Not Cancer Driver | No | 51 | 0.111 | 126 | 15 | 0.119 | 1 |
| CORO1B | CORO1B | Q9BR76 | Coronin-1B | chr11 | GO:0005884 | Not Cancer Driver | No | 41 | 0.084 | 138 | 10 | 0.072 | 0 |
| COTL1 | COTL1 | Q14019 | Coactosin-like protein | chr16 | GO:0005884 | Not Cancer Driver | No | 17 | 0.12 | 7 | 2 | 0.286 | 0 |
| CTTN_ENST00000301843 | CTTN | Q14247 | Src substrate cortactin | chr11 | GO:0005884 | Not Cancer Driver | No | 78 | 0.142 | 465 | 56 | 0.12 | 0 |
| DBN1_ENST00000309007 | DBN1 | Q16643 | Drebrin | chr5 | GO:0005884 | Not Cancer Driver | No | 84 | 0.129 | 510 | 73 | 0.143 | 0 |
| DBNL_ENST00000448521 | DBNL | Q9UJU6 | Drebrin-like protein | chr7 | GO:0005884 | Not Cancer Driver | No | 46 | 0.107 | 304 | 31 | 0.102 | 0 |
| DIAPH1 | DIAPH1 | O60610 | Protein diaphanous homolog 1 | chr5 | GO:0005884 | Not Cancer Driver | No | 118 | 0.093 | 692 | 57 | 0.082 | 1 |
| DIAPH2 | DIAPH2 | O60879 | Protein diaphanous homolog 2 | chrX | GO:0005884 | Not Cancer Driver | No | 195 | 0.177 | 460 | 95 | 0.207 | 0 |
| DIAPH3 | DIAPH3 | Q9NSV4 | Protein diaphanous homolog 3 | chr13 | GO:0005884 | Not Cancer Driver | No | 189 | 0.158 | 492 | 78 | 0.159 | 0 |
| DMTN_ENST00000358242 | DMTN | Q08495 | Dematin | chr8 | GO:0005884 | Not Cancer Driver | No | 53 | 0.131 | 348 | 46 | 0.132 | 0 |
| DNAJA3 | DNAJA3 | Q96EY1 | DnaJ homolog subfamily A member 3, mitochondrial | chr16 | GO:0005884 | Not Cancer Driver | No | 50 | 0.104 | 152 | 21 | 0.138 | 0 |
| EZR | EZR | P15311 | Ezrin | chr6 | GO:0005884 | Census | Yes | 66 | 0.113 | 295 | 35 | 0.119 | 0 |
| FHDC1 | FHDC1 | Q9C0D6 | FH2 domain-containing protein 1 | chr4 | GO:0005884 | Not Cancer Driver | No | 179 | 0.157 | 855 | 136 | 0.159 | 0 |
| FMN1 | FMN1 | Q68DA7 | Formin-1 | chr15 | GO:0005884 | Not Cancer Driver | No | 117 | 0.082 | 983 | 67 | 0.068 | 0 |
| FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0005884 | Not Cancer Driver | No | 92 | 0.171 | 70 | 13 | 0.186 | 0 |
| GAS2 | GAS2 | O43903 | Growth arrest-specific protein 2 | chr11 | GO:0005884 | Not Cancer Driver | No | 73 | 0.233 | 92 | 16 | 0.174 | 0 |
| GAS2L1_ENST00000621062 | GAS2L1 | Q99501 | GAS2-like protein 1 | chr22 | GO:0005884 | Not Cancer Driver | No | 76 | 0.112 | 474 | 50 | 0.105 | 0 |
| GAS2L3_ENST00000266754 | GAS2L3 | Q86XJ1 | GAS2-like protein 3 | chr12 | GO:0005884 | Not Cancer Driver | No | 89 | 0.128 | 416 | 52 | 0.125 | 0 |
| GAS7 | GAS7 | O60861 | Growth arrest-specific protein 7 | chr17 | GO:0005884 | Census | Yes | 78 | 0.164 | 318 | 57 | 0.179 | 0 |
| GDPD2_ENST00000374382 | GDPD2 | Q9HCC8 | Glycerophosphoinositol inositolphosphodiesterase GDPD2 | chrX | GO:0005884 | Not Cancer Driver | No | 96 | 0.178 | 43 | 15 | 0.349 | 0 |
| GJB6_ENST00000644667 | GJB6 | O95452 | Gap junction beta-6 protein | chr13 | GO:0005884 | Not Cancer Driver | No | 42 | 0.161 | 12 | 4 | 0.333 | 4 |
| HCK_ENST00000534862 | HCK | P08631 | Tyrosine-protein kinase HCK | chr20 | GO:0005884 | Not Cancer Driver | No | 112 | 0.213 | 124 | 25 | 0.202 | 0 |
| HCLS1 | HCLS1 | P14317 | Hematopoietic lineage cell-specific protein | chr3 | GO:0005884 | Not Cancer Driver | No | 103 | 0.212 | 446 | 94 | 0.211 | 0 |
| IQGAP1 | IQGAP1 | P46940 | Ras GTPase-activating-like protein IQGAP1 | chr15 | GO:0005884 | Not Cancer Driver | No | 183 | 0.11 | 351 | 35 | 0.1 | 0 |
| KEAP1_ENST00000393623 | KEAP1 | Q14145 | Kelch-like ECH-associated protein 1 | chr19 | GO:0005884 | Census, Compendium | Yes | 237 | 0.38 | 57 | 12 | 0.211 | 0 |
| LCP1 | LCP1 | P13796 | Plastin-2 | chr13 | GO:0005884 | Census | Yes | 99 | 0.158 | 73 | 11 | 0.151 | 0 |
| LMOD1 | LMOD1 | P29536 | Leiomodin-1 | chr1 | GO:0005884 | Not Cancer Driver | No | 97 | 0.162 | 499 | 80 | 0.16 | 0 |
| LMOD2 | LMOD2 | Q6P5Q4 | Leiomodin-2 | chr7 | GO:0005884 | Not Cancer Driver | No | 94 | 0.172 | 451 | 79 | 0.175 | 0 |
| MARK2 | MARK2 | Q7KZI7 | Serine/threonine-protein kinase MARK2 | chr11 | GO:0005884 | Compendium | Yes | 124 | 0.157 | 445 | 70 | 0.157 | 0 |
| MISP | MISP | Q8IVT2 | Mitotic interactor and substrate of PLK1 | chr19 | GO:0005884 | Not Cancer Driver | No | 138 | 0.203 | 646 | 132 | 0.204 | 0 |
| MYO1B | MYO1B | O43795 | Unconventional myosin-Ib | chr2 | GO:0005884 | Not Cancer Driver | No | 144 | 0.127 | 34 | 4 | 0.118 | 0 |
| MYO5A | MYO5A | Q9Y4I1 | Unconventional myosin-Va | chr15 | GO:0005884 | Census, Compendium | Yes | 224 | 0.121 | 497 | 58 | 0.117 | 0 |
| MYO6 | MYO6 | Q9UM54 | Unconventional myosin-VI | chr6 | GO:0005884 | Not Cancer Driver | No | 176 | 0.136 | 342 | 41 | 0.12 | 3 |
| MYO9B_ENST00000594824 | MYO9B | Q13459 | Unconventional myosin-IXb | chr19 | GO:0005884 | Not Cancer Driver | No | 226 | 0.105 | 827 | 80 | 0.097 | 0 |
| PAK1_ENST00000356341 | PAK1 | Q13153 | Serine/threonine-protein kinase PAK 1 | chr11 | GO:0005884 | Not Cancer Driver | No | 57 | 0.105 | 299 | 30 | 0.1 | 2 |
| PAWR | PAWR | Q96IZ0 | PRKC apoptosis WT1 regulator protein | chr12 | GO:0005884 | Not Cancer Driver | No | 35 | 0.103 | 327 | 33 | 0.101 | 0 |
| PLS1 | PLS1 | Q14651 | Plastin-1 | chr3 | GO:0005884 | Not Cancer Driver | No | 100 | 0.159 | 59 | 8 | 0.136 | 4 |
| PLS3_ENST00000539310 | PLS3 | P13797 | Plastin-3 | chrX | GO:0005884 | Not Cancer Driver | No | 75 | 0.119 | 75 | 5 | 0.067 | 0 |
| POF1B_ENST00000262753 | POF1B | Q8WVV4 | Protein POF1B | chrX | GO:0005884 | Not Cancer Driver | No | 154 | 0.261 | 391 | 104 | 0.266 | 1 |
| PSTPIP1 | PSTPIP1 | O43586 | Proline-serine-threonine phosphatase-interacting protein 1 | chr15 | GO:0005884 | Not Cancer Driver | No | 46 | 0.111 | 225 | 26 | 0.116 | 3 |
| PSTPIP2 | PSTPIP2 | Q9H939 | Proline-serine-threonine phosphatase-interacting protein 2 | chr18 | GO:0005884 | Not Cancer Driver | No | 50 | 0.15 | 89 | 22 | 0.247 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | GO:0005884 | Census, Compendium | Yes | 66 | 0.344 | 2 | 1 | 0.5 | 6 |
| RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | GO:0005884 | Not Cancer Driver | No | 31 | 0.161 | 0 | 0 | 0.0 | 2 |
| RCSD1 | RCSD1 | Q6JBY9 | CapZ-interacting protein | chr1 | GO:0005884 | Not Cancer Driver | No | 70 | 0.168 | 416 | 70 | 0.168 | 0 |
| RHOQ | RHOQ | P17081 | Rho-related GTP-binding protein RhoQ | chr2 | GO:0005884 | Not Cancer Driver | No | 25 | 0.122 | 0 | 0 | 0.0 | 0 |
| SHROOM4 | SHROOM4 | Q9ULL8 | Protein Shroom4 | chrX | GO:0005884 | Not Cancer Driver | No | 242 | 0.162 | 1027 | 167 | 0.163 | 1 |
| SPTBN4_ENST00000598249 | SPTBN4 | Q9H254 | Spectrin beta chain, non-erythrocytic 4 | chr19 | GO:0005884 | Not Cancer Driver | No | 312 | 0.122 | 866 | 103 | 0.119 | 0 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0005884 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| TEK | TEK | Q02763 | Angiopoietin-1 receptor | chr9 | GO:0005884 | Not Cancer Driver | No | 219 | 0.195 | 126 | 22 | 0.175 | 10 |
| TFPT | TFPT | P0C1Z6 | TCF3 fusion partner | chr19 | GO:0005884 | Census | Yes | 41 | 0.162 | 237 | 41 | 0.173 | 0 |
| TMOD1_ENST00000395211 | TMOD1 | P28289 | Tropomodulin-1 | chr9 | GO:0005884 | Not Cancer Driver | No | 41 | 0.114 | 195 | 29 | 0.149 | 0 |
| TPM1_ENST00000403994 | TPM1 | P09493 | Tropomyosin alpha-1 chain | chr15 | GO:0005884 | Not Cancer Driver | No | 33 | 0.116 | 234 | 29 | 0.124 | 8 |
| TPM2 | TPM2 | P07951 | Tropomyosin beta chain | chr9 | GO:0005884 | Not Cancer Driver | No | 39 | 0.137 | 232 | 35 | 0.151 | 15 |
| TPM3 | TPM3 | P06753 | Tropomyosin alpha-3 chain | chr1 | GO:0005884 | Census | Yes | 35 | 0.123 | 230 | 27 | 0.117 | 21 |
| TPM4_ENST00000300933 | TPM4 | P67936 | Tropomyosin alpha-4 chain | chr19 | GO:0005884 | Census | Yes | 28 | 0.113 | 216 | 28 | 0.13 | 0 |
| TSC1 | TSC1 | Q92574 | Hamartin | chr9 | GO:0005884 | Census, Compendium | Yes | 135 | 0.116 | 732 | 78 | 0.107 | 11 |
| TWF1_ENST00000395510 | TWF1 | Q12792 | Twinfilin-1 | chr12 | GO:0005884 | Not Cancer Driver | No | 50 | 0.143 | 52 | 3 | 0.058 | 0 |
| TWF2 | TWF2 | Q6IBS0 | Twinfilin-2 | chr3 | GO:0005884 | Not Cancer Driver | No | 34 | 0.097 | 59 | 8 | 0.136 | 0 |
| VPS18 | VPS18 | Q9P253 | Vacuolar protein sorting-associated protein 18 homolog | chr15 | GO:0005884 | Not Cancer Driver | No | 96 | 0.099 | 86 | 7 | 0.081 | 0 |
| WAS | WAS | P42768 | Wiskott-Aldrich syndrome protein | chrX | GO:0005884 | Census, Compendium | Yes | 75 | 0.149 | 400 | 55 | 0.138 | 30 |
| WASL | WASL | O00401 | Neural Wiskott-Aldrich syndrome protein | chr7 | GO:0005884 | Not Cancer Driver | No | 72 | 0.143 | 394 | 57 | 0.145 | 0 |
| WHRN | WHRN | Q9P202 | Whirlin | chr9 | GO:0005884 | Not Cancer Driver | No | 119 | 0.131 | 484 | 53 | 0.11 | 0 |
| WIPF1_ENST00000359761 | WIPF1 | O43516 | WAS/WASL-interacting protein family member 1 | chr2 | GO:0005884 | Not Cancer Driver | No | 110 | 0.219 | 503 | 110 | 0.219 | 0 |
| WIPF2 | WIPF2 | Q8TF74 | WAS/WASL-interacting protein family member 2 | chr17 | GO:0005884 | Not Cancer Driver | No | 71 | 0.161 | 440 | 71 | 0.161 | 0 |
| WIPF3_ENST00000409290 | WIPF3 | A6NGB9 | WAS/WASL-interacting protein family member 3 | chr7 | GO:0005884 | Not Cancer Driver | No | 41 | 0.085 | 483 | 41 | 0.085 | 0 |
| YES1_ENST00000314574 | YES1 | P07947 | Tyrosine-protein kinase Yes | chr18 | GO:0005884 | Not Cancer Driver | No | 65 | 0.12 | 62 | 10 | 0.161 | 0 |