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Total number of protein in "GO:0005506" GO term:  130

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCE1 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 GO:0005506 Not Cancer Driver No 74 0.124 36 6 0.167 0
ACO2 ACO2 Q99798 Aconitate hydratase, mitochondrial chr22 GO:0005506 Not Cancer Driver No 94 0.121 172 19 0.11 5
ACP5_ENST00000433365 ACP5 P13686 Tartrate-resistant acid phosphatase type 5 chr19 GO:0005506 Not Cancer Driver No 51 0.157 31 6 0.194 8
ADI1 ADI1 Q9BV57 Acireductone dioxygenase chr2 GO:0005506 Not Cancer Driver No 27 0.151 23 1 0.043 0
AGMO AGMO Q6ZNB7 Alkylglycerol monooxygenase chr7 GO:0005506 Not Cancer Driver No 134 0.301 7 2 0.286 0
ALKBH8_ENST00000389568 ALKBH8 Q96BT7 Alkylated DNA repair protein alkB homolog 8 chr11 GO:0005506 Not Cancer Driver No 50 0.075 189 12 0.063 0
ALOX12 ALOX12 P18054 Polyunsaturated fatty acid lipoxygenase ALOX12 chr17 GO:0005506 Not Cancer Driver No 73 0.11 73 12 0.164 0
ALOX12B ALOX12B O75342 Arachidonate 12-lipoxygenase, 12R-type chr17 GO:0005506 Not Cancer Driver No 101 0.144 16 3 0.188 18
ALOX15B ALOX15B O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B chr17 GO:0005506 Not Cancer Driver No 99 0.146 62 12 0.194 0
ALOX15_ENST00000293761 ALOX15 P16050 Polyunsaturated fatty acid lipoxygenase ALOX15 chr17 GO:0005506 Not Cancer Driver No 84 0.127 46 7 0.152 0
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0005506 Not Cancer Driver No 129 0.191 16 2 0.125 0
ALOXE3_ENST00000448843 ALOXE3 Q9BYJ1 Hydroperoxide isomerase ALOXE3 chr17 GO:0005506 Not Cancer Driver No 108 0.152 69 13 0.188 6
AOX1 AOX1 Q06278 Aldehyde oxidase chr2 GO:0005506 Not Cancer Driver No 238 0.178 70 11 0.157 0
BBOX1_ENST00000525090 BBOX1 O75936 Gamma-butyrobetaine dioxygenase chr11 GO:0005506 Not Cancer Driver No 59 0.152 0 0 0.0 0
CALR CALR P27797 Calreticulin chr19 GO:0005506 Census Yes 45 0.108 245 31 0.127 0
CH25H CH25H O95992 Cholesterol 25-hydroxylase chr10 GO:0005506 Not Cancer Driver No 37 0.136 0 0 0.0 0
CYGB CYGB Q8WWM9 Cytoglobin chr17 GO:0005506 Not Cancer Driver No 32 0.168 47 5 0.106 0
CYP11A1 CYP11A1 P05108 Cholesterol side-chain cleavage enzyme, mitochondrial chr15 GO:0005506 Not Cancer Driver No 92 0.177 27 6 0.222 6
CYP11B1 CYP11B1 P15538 Cytochrome P450 11B1, mitochondrial chr8 GO:0005506 Not Cancer Driver No 177 0.352 7 1 0.143 50
CYP11B2 CYP11B2 P19099 Cytochrome P450 11B2, mitochondrial chr8 GO:0005506 Not Cancer Driver No 148 0.294 6 0 0.0 6
CYP17A1 CYP17A1 P05093 Steroid 17-alpha-hydroxylase/17,20 lyase chr10 GO:0005506 Not Cancer Driver No 64 0.126 34 2 0.059 26
CYP19A1_ENST00000396404 CYP19A1 P11511 Aromatase chr15 GO:0005506 Not Cancer Driver No 91 0.181 2 1 0.5 5
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 GO:0005506 Not Cancer Driver No 81 0.158 17 2 0.118 0
CYP1A2 CYP1A2 P05177 Cytochrome P450 1A2 chr15 GO:0005506 Not Cancer Driver No 93 0.18 23 3 0.13 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0005506 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP20A1 CYP20A1 Q6UW02 Cytochrome P450 20A1 chr2 GO:0005506 Not Cancer Driver No 56 0.121 35 8 0.229 0
CYP21A2_ENST00000643666 CYP21A2 P08686 Steroid 21-hydroxylase chr6 GO:0005506 Not Cancer Driver No 70 0.142 49 16 0.327 66
CYP24A1 CYP24A1 Q07973 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial chr20 GO:0005506 Not Cancer Driver No 74 0.144 77 5 0.065 4
CYP26A1 CYP26A1 O43174 Cytochrome P450 26A1 chr10 GO:0005506 Not Cancer Driver No 84 0.169 9 1 0.111 0
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0005506 Not Cancer Driver No 113 0.221 10 3 0.3 2
CYP26C1 CYP26C1 Q6V0L0 Cytochrome P450 26C1 chr10 GO:0005506 Not Cancer Driver No 32 0.061 56 6 0.107 0
CYP27A1 CYP27A1 Q02318 Sterol 26-hydroxylase, mitochondrial chr2 GO:0005506 Not Cancer Driver No 69 0.13 47 11 0.234 7
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0005506 Not Cancer Driver No 71 0.14 79 13 0.165 18
CYP2A13 CYP2A13 Q16696 Cytochrome P450 2A13 chr19 GO:0005506 Not Cancer Driver No 122 0.247 38 9 0.237 0
CYP2A6 CYP2A6 P11509 Cytochrome P450 2A6 chr19 GO:0005506 Not Cancer Driver No 107 0.217 40 10 0.25 0
CYP2A7 CYP2A7 P20853 Cytochrome P450 2A7 chr19 GO:0005506 Not Cancer Driver No 95 0.192 39 9 0.231 0
CYP2B6 CYP2B6 P20813 Cytochrome P450 2B6 chr19 GO:0005506 Not Cancer Driver No 137 0.279 39 13 0.333 0
CYP2C18 CYP2C18 P33260 Cytochrome P450 2C18 chr10 GO:0005506 Not Cancer Driver No 114 0.233 11 1 0.091 0
CYP2C19 CYP2C19 P33261 Cytochrome P450 2C19 chr10 GO:0005506 Not Cancer Driver No 157 0.32 32 12 0.375 0
CYP2C8 CYP2C8 P10632 Cytochrome P450 2C8 chr10 GO:0005506 Census, Compendium Yes 113 0.231 30 11 0.367 0
CYP2C9 CYP2C9 P11712 Cytochrome P450 2C9 chr10 GO:0005506 Not Cancer Driver No 122 0.249 36 14 0.389 0
CYP2D6_ENST00000645361 CYP2D6 P10635 Cytochrome P450 2D6 chr22 GO:0005506 Not Cancer Driver No 76 0.153 66 8 0.121 0
CYP2D7 CYP2D7 A0A087X1C5 Putative cytochrome P450 2D7 chr22 GO:0005506 Not Cancer Driver No 74 0.144 60 6 0.1 0
CYP2E1_ENST00000252945 CYP2E1 P05181 Cytochrome P450 2E1 chr10 GO:0005506 Not Cancer Driver No 87 0.176 21 6 0.286 0
CYP2F1 CYP2F1 P24903 Cytochrome P450 2F1 chr19 GO:0005506 Not Cancer Driver No 85 0.173 2 0 0.0 0
CYP2J2 CYP2J2 P51589 Cytochrome P450 2J2 chr1 GO:0005506 Not Cancer Driver No 58 0.116 63 6 0.095 0
CYP2R1 CYP2R1 Q6VVX0 Vitamin D 25-hydroxylase chr11 GO:0005506 Not Cancer Driver No 53 0.106 5 1 0.2 1
CYP2S1 CYP2S1 Q96SQ9 Cytochrome P450 2S1 chr19 GO:0005506 Not Cancer Driver No 75 0.149 46 10 0.217 0
CYP2U1 CYP2U1 Q7Z449 Cytochrome P450 2U1 chr4 GO:0005506 Not Cancer Driver No 37 0.068 38 2 0.053 4
CYP2W1 CYP2W1 Q8TAV3 Cytochrome P450 2W1 chr7 GO:0005506 Not Cancer Driver No 51 0.104 55 6 0.109 0
CYP39A1 CYP39A1 Q9NYL5 24-hydroxycholesterol 7-alpha-hydroxylase chr6 GO:0005506 Not Cancer Driver No 61 0.13 3 0 0.0 0
CYP3A4 CYP3A4 P08684 Cytochrome P450 3A4 chr7 GO:0005506 Not Cancer Driver No 91 0.181 22 2 0.091 1
CYP3A43_ENST00000354829 CYP3A43 Q9HB55 Cytochrome P450 3A43 chr7 GO:0005506 Not Cancer Driver No 79 0.157 5 0 0.0 0
CYP3A5 CYP3A5 P20815 Cytochrome P450 3A5 chr7 GO:0005506 Not Cancer Driver No 67 0.133 38 5 0.132 0
CYP3A7 CYP3A7 P24462 Cytochrome P450 3A7 chr7 GO:0005506 Not Cancer Driver No 91 0.181 17 6 0.353 0
CYP46A1 CYP46A1 Q9Y6A2 Cholesterol 24-hydroxylase chr14 GO:0005506 Not Cancer Driver No 92 0.184 23 4 0.174 0
CYP4A11 CYP4A11 Q02928 Cytochrome P450 4A11 chr1 GO:0005506 Not Cancer Driver No 131 0.252 24 8 0.333 0
CYP4A22 CYP4A22 Q5TCH4 Cytochrome P450 4A22 chr1 GO:0005506 Not Cancer Driver No 116 0.224 26 6 0.231 0
CYP4B1_ENST00000271153 CYP4B1 P13584 Cytochrome P450 4B1 chr1 GO:0005506 Not Cancer Driver No 124 0.243 8 2 0.25 0
CYP4F11 CYP4F11 Q9HBI6 Cytochrome P450 4F11 chr19 GO:0005506 Not Cancer Driver No 132 0.252 11 2 0.182 0
CYP4F12_ENST00000324632 CYP4F12 Q9HCS2 Cytochrome P450 4F12 chr19 GO:0005506 Not Cancer Driver No 138 0.263 18 4 0.222 0
CYP4F2 CYP4F2 P78329 Cytochrome P450 4F2 chr19 GO:0005506 Not Cancer Driver No 136 0.262 17 3 0.176 0
CYP4F22_ENST00000601005 CYP4F22 Q6NT55 Ultra-long-chain fatty acid omega-hydroxylase chr19 GO:0005506 Not Cancer Driver No 103 0.194 30 3 0.1 5
CYP4F3 CYP4F3 Q08477 Cytochrome P450 4F3 chr19 GO:0005506 Not Cancer Driver No 125 0.24 15 7 0.467 0
CYP4F8 CYP4F8 P98187 Cytochrome P450 4F8 chr19 GO:0005506 Not Cancer Driver No 108 0.208 28 10 0.357 0
CYP4V2 CYP4V2 Q6ZWL3 Cytochrome P450 4V2 chr4 GO:0005506 Not Cancer Driver No 67 0.128 46 9 0.196 8
CYP4X1 CYP4X1 Q8N118 Cytochrome P450 4X1 chr1 GO:0005506 Not Cancer Driver No 86 0.169 14 7 0.5 0
CYP4Z1 CYP4Z1 Q86W10 Cytochrome P450 4Z1 chr1 GO:0005506 Not Cancer Driver No 106 0.21 14 8 0.571 0
CYP51A1 CYP51A1 Q16850 Lanosterol 14-alpha demethylase chr7 GO:0005506 Not Cancer Driver No 49 0.096 7 2 0.286 0
CYP7A1 CYP7A1 P22680 Cytochrome P450 7A1 chr8 GO:0005506 Not Cancer Driver No 109 0.216 48 8 0.167 0
CYP7B1 CYP7B1 O75881 Cytochrome P450 7B1 chr8 GO:0005506 Not Cancer Driver No 133 0.263 0 0 0.0 11
CYP8B1 CYP8B1 Q9UNU6 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase chr3 GO:0005506 Not Cancer Driver No 91 0.182 5 1 0.2 0
DOHH DOHH Q9BU89 Deoxyhypusine hydroxylase chr19 GO:0005506 Not Cancer Driver No 30 0.099 56 6 0.107 0
ETHE1 ETHE1 O95571 Persulfide dioxygenase ETHE1, mitochondrial chr19 GO:0005506 Not Cancer Driver No 21 0.083 6 0 0.0 9
FA2H FA2H Q7L5A8 Fatty acid 2-hydroxylase chr16 GO:0005506 Not Cancer Driver No 33 0.089 73 0 0.0 3
FAXDC2 FAXDC2 Q96IV6 Fatty acid hydroxylase domain-containing protein 2 chr5 GO:0005506 Not Cancer Driver No 39 0.117 9 0 0.0 0
FBXL5 FBXL5 Q9UKA1 F-box/LRR-repeat protein 5 chr4 GO:0005506 Not Cancer Driver No 80 0.116 70 7 0.1 0
FDX1 FDX1 P10109 Adrenodoxin, mitochondrial chr11 GO:0005506 Not Cancer Driver No 12 0.065 61 2 0.033 0
FTH1_ENST00000620041 FTH1 P02794 Ferritin heavy chain chr11 GO:0005506 Not Cancer Driver No 20 0.109 57 7 0.123 0
FTHL17 FTHL17 Q9BXU8 Ferritin heavy polypeptide-like 17 chrX GO:0005506 Not Cancer Driver No 63 0.344 9 1 0.111 0
FTL FTL P02792 Ferritin light chain chr19 GO:0005506 Not Cancer Driver No 19 0.109 36 7 0.194 2
FTMT FTMT Q8N4E7 Ferritin, mitochondrial chr5 GO:0005506 Not Cancer Driver No 96 0.397 93 33 0.355 0
FXN FXN Q16595 Frataxin, mitochondrial chr9 GO:0005506 Not Cancer Driver No 16 0.076 73 0 0.0 8
HBA2 HBA2 P69905 Hemoglobin subunit alpha chr16 GO:0005506 Not Cancer Driver No 9 0.063 4 0 0.0 0
HBQ1 HBQ1 P09105 Hemoglobin subunit theta-1 chr16 GO:0005506 Not Cancer Driver No 10 0.07 0 0 0.0 0
HBZ HBZ P02008 Hemoglobin subunit zeta chr16 GO:0005506 Not Cancer Driver No 9 0.063 0 0 0.0 0
ISCA2 ISCA2 Q86U28 Iron-sulfur cluster assembly 2 homolog, mitochondrial chr14 GO:0005506 Not Cancer Driver No 13 0.084 38 3 0.079 1
ISCU ISCU Q9H1K1 Iron-sulfur cluster assembly enzyme ISCU, mitochondrial chr12 GO:0005506 Not Cancer Driver No 14 0.084 24 3 0.125 0
JMJD6_ENST00000397625 JMJD6 Q6NYC1 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 chr17 GO:0005506 Not Cancer Driver No 51 0.127 133 21 0.158 0
KDM3A_ENST00000312912 KDM3A Q9Y4C1 Lysine-specific demethylase 3A chr2 GO:0005506 Not Cancer Driver No 136 0.103 461 47 0.102 0
KDM7A KDM7A Q6ZMT4 Lysine-specific demethylase 7A chr7 GO:0005506 Not Cancer Driver No 112 0.119 444 54 0.122 0
LCN2_ENST00000277480 LCN2 P80188 Neutrophil gelatinase-associated lipocalin chr9 GO:0005506 Not Cancer Driver No 29 0.146 4 3 0.75 0
LTF LTF P02788 Lactotransferrin chr3 GO:0005506 Not Cancer Driver No 131 0.185 21 4 0.19 0
MELTF MELTF P08582 Melanotransferrin chr3 GO:0005506 Not Cancer Driver No 106 0.144 23 6 0.261 0
MIOX MIOX Q9UGB7 Inositol oxygenase chr22 GO:0005506 Not Cancer Driver No 48 0.168 21 4 0.19 0
MSMO1 MSMO1 Q15800 Methylsterol monooxygenase 1 chr4 GO:0005506 Not Cancer Driver No 42 0.143 4 0 0.0 2
NFU1 NFU1 Q9UMS0 NFU1 iron-sulfur cluster scaffold homolog, mitochondrial chr2 GO:0005506 Not Cancer Driver No 37 0.146 48 7 0.146 4
OGFOD1 OGFOD1 Q8N543 Prolyl 3-hydroxylase OGFOD1 chr16 GO:0005506 Not Cancer Driver No 44 0.081 156 6 0.038 0
OGFOD2 OGFOD2 Q6N063 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 chr12 GO:0005506 Not Cancer Driver No 32 0.091 34 1 0.029 0
OGFOD3_ENST00000313056 OGFOD3 Q6PK18 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 chr17 GO:0005506 Not Cancer Driver No 52 0.163 51 5 0.098 0
P3H1_ENST00000296388 P3H1 Q32P28 Prolyl 3-hydroxylase 1 chr1 GO:0005506 Not Cancer Driver No 91 0.124 177 18 0.102 0
P3H2 P3H2 Q8IVL5 Prolyl 3-hydroxylase 2 chr3 GO:0005506 Not Cancer Driver No 131 0.185 160 24 0.15 1
P3H3 P3H3 Q8IVL6 Prolyl 3-hydroxylase 3 chr12 GO:0005506 Not Cancer Driver No 84 0.114 307 40 0.13 0
P4HA1_ENST00000394890 P4HA1 P13674 Prolyl 4-hydroxylase subunit alpha-1 chr10 GO:0005506 Not Cancer Driver No 65 0.122 54 8 0.148 0
P4HA2_ENST00000379104 P4HA2 O15460 Prolyl 4-hydroxylase subunit alpha-2 chr5 GO:0005506 Not Cancer Driver No 66 0.123 82 12 0.146 2
P4HA3_ENST00000331597 P4HA3 Q7Z4N8 Prolyl 4-hydroxylase subunit alpha-3 chr11 GO:0005506 Not Cancer Driver No 70 0.129 17 2 0.118 0
P4HTM_ENST00000383729 P4HTM Q9NXG6 Transmembrane prolyl 4-hydroxylase chr3 GO:0005506 Not Cancer Driver No 76 0.151 144 20 0.139 1
PAH PAH P00439 Phenylalanine-4-hydroxylase chr12 GO:0005506 Not Cancer Driver No 133 0.294 13 4 0.308 222
PHF2 PHF2 O75151 Lysine-specific demethylase PHF2 chr9 GO:0005506 Not Cancer Driver No 131 0.12 725 80 0.11 0
PHF8 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX GO:0005506 Not Cancer Driver No 154 0.145 603 93 0.154 1
PLOD1 PLOD1 Q02809 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 chr1 GO:0005506 Not Cancer Driver No 86 0.118 12 0 0.0 5
PLOD2_ENST00000360060 PLOD2 O00469 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 chr3 GO:0005506 Not Cancer Driver No 109 0.148 17 3 0.176 4
PLOD3 PLOD3 O60568 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 chr7 GO:0005506 Not Cancer Driver No 108 0.146 65 8 0.123 1
PPEF1 PPEF1 O14829 Serine/threonine-protein phosphatase with EF-hands 1 chrX GO:0005506 Not Cancer Driver No 127 0.194 66 10 0.152 0
PPEF2 PPEF2 O14830 Serine/threonine-protein phosphatase with EF-hands 2 chr4 GO:0005506 Not Cancer Driver No 144 0.191 130 29 0.223 0
PTGIS PTGIS Q16647 Prostacyclin synthase chr20 GO:0005506 Not Cancer Driver No 102 0.204 18 3 0.167 0
RIOX1 RIOX1 Q9H6W3 Ribosomal oxygenase 1 chr14 GO:0005506 Not Cancer Driver No 52 0.081 215 15 0.07 0
RRM2_ENST00000641198 RRM2 P31350 Ribonucleoside-diphosphate reductase subunit M2 chr2 GO:0005506 Not Cancer Driver No 40 0.103 48 0 0.0 0
SC5D_ENST00000392789 SC5D O75845 Lathosterol oxidase chr11 GO:0005506 Not Cancer Driver No 43 0.144 21 3 0.143 3
SCD SCD O00767 Stearoyl-CoA desaturase chr10 GO:0005506 Not Cancer Driver No 36 0.1 18 0 0.0 0
SCD5 SCD5 Q86SK9 Stearoyl-CoA desaturase 5 chr4 GO:0005506 Not Cancer Driver No 43 0.13 42 8 0.19 0
TBXAS1_ENST00000448866 TBXAS1 P24557 Thromboxane-A synthase chr7 GO:0005506 Not Cancer Driver No 116 0.218 44 8 0.182 4
TET1 TET1 Q8NFU7 Methylcytosine dioxygenase TET1 chr10 GO:0005506 Census, Compendium Yes 316 0.148 1551 234 0.151 0
TF TF P02787 Serotransferrin chr3 GO:0005506 Not Cancer Driver No 135 0.193 21 5 0.238 2
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0005506 Not Cancer Driver No 61 0.116 149 21 0.141 38
TMLHE TMLHE Q9NVH6 Trimethyllysine dioxygenase, mitochondrial chrX GO:0005506 Not Cancer Driver No 49 0.116 4 0 0.0 1
TPH1 TPH1 P17752 Tryptophan 5-hydroxylase 1 chr11 GO:0005506 Not Cancer Driver No 80 0.18 14 3 0.214 0
TPH2 TPH2 Q8IWU9 Tryptophan 5-hydroxylase 2 chr12 GO:0005506 Not Cancer Driver No 118 0.241 55 17 0.309 1
TYW5 TYW5 A2RUC4 tRNA wybutosine-synthesizing protein 5 chr2 GO:0005506 Not Cancer Driver No 32 0.102 11 1 0.091 0
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0005506 Not Cancer Driver No 279 0.209 134 24 0.179 1