Total number of protein in "GO:0004497" GO term: 96
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGMO | AGMO | Q6ZNB7 | Alkylglycerol monooxygenase | chr7 | GO:0004497 | Not Cancer Driver | No | 134 | 0.301 | 7 | 2 | 0.286 | 0 |
| AKR1C1 | AKR1C1 | Q04828 | Aldo-keto reductase family 1 member C1 | chr10 | GO:0004497 | Not Cancer Driver | No | 56 | 0.173 | 1 | 0 | 0.0 | 0 |
| AKR1C2 | AKR1C2 | P52895 | Aldo-keto reductase family 1 member C2 | chr10 | GO:0004497 | Not Cancer Driver | No | 32 | 0.099 | 1 | 0 | 0.0 | 4 |
| AKR1C3 | AKR1C3 | P42330 | Aldo-keto reductase family 1 member C3 | chr10 | GO:0004497 | Not Cancer Driver | No | 49 | 0.152 | 11 | 1 | 0.091 | 0 |
| AKR1C4 | AKR1C4 | P17516 | Aldo-keto reductase family 1 member C4 | chr10 | GO:0004497 | Not Cancer Driver | No | 78 | 0.241 | 9 | 3 | 0.333 | 0 |
| AKR1D1 | AKR1D1 | P51857 | Aldo-keto reductase family 1 member D1 | chr7 | GO:0004497 | Not Cancer Driver | No | 89 | 0.273 | 15 | 3 | 0.2 | 5 |
| CH25H | CH25H | O95992 | Cholesterol 25-hydroxylase | chr10 | GO:0004497 | Not Cancer Driver | No | 37 | 0.136 | 0 | 0 | 0.0 | 0 |
| COQ6 | COQ6 | Q9Y2Z9 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial | chr14 | GO:0004497 | Not Cancer Driver | No | 58 | 0.124 | 20 | 2 | 0.1 | 2 |
| COQ7_ENST00000568985 | COQ7 | Q99807 | 5-demethoxyubiquinone hydroxylase, mitochondrial | chr16 | GO:0004497 | Not Cancer Driver | No | 27 | 0.124 | 5 | 1 | 0.2 | 1 |
| CYP11A1 | CYP11A1 | P05108 | Cholesterol side-chain cleavage enzyme, mitochondrial | chr15 | GO:0004497 | Not Cancer Driver | No | 92 | 0.177 | 27 | 6 | 0.222 | 6 |
| CYP11B1 | CYP11B1 | P15538 | Cytochrome P450 11B1, mitochondrial | chr8 | GO:0004497 | Not Cancer Driver | No | 177 | 0.352 | 7 | 1 | 0.143 | 50 |
| CYP11B2 | CYP11B2 | P19099 | Cytochrome P450 11B2, mitochondrial | chr8 | GO:0004497 | Not Cancer Driver | No | 148 | 0.294 | 6 | 0 | 0.0 | 6 |
| CYP17A1 | CYP17A1 | P05093 | Steroid 17-alpha-hydroxylase/17,20 lyase | chr10 | GO:0004497 | Not Cancer Driver | No | 64 | 0.126 | 34 | 2 | 0.059 | 26 |
| CYP19A1_ENST00000396404 | CYP19A1 | P11511 | Aromatase | chr15 | GO:0004497 | Not Cancer Driver | No | 91 | 0.181 | 2 | 1 | 0.5 | 5 |
| CYP1A1 | CYP1A1 | P04798 | Cytochrome P450 1A1 | chr15 | GO:0004497 | Not Cancer Driver | No | 81 | 0.158 | 17 | 2 | 0.118 | 0 |
| CYP1A2 | CYP1A2 | P05177 | Cytochrome P450 1A2 | chr15 | GO:0004497 | Not Cancer Driver | No | 93 | 0.18 | 23 | 3 | 0.13 | 0 |
| CYP1B1 | CYP1B1 | Q16678 | Cytochrome P450 1B1 | chr2 | GO:0004497 | Not Cancer Driver | No | 61 | 0.112 | 31 | 3 | 0.097 | 40 |
| CYP20A1 | CYP20A1 | Q6UW02 | Cytochrome P450 20A1 | chr2 | GO:0004497 | Not Cancer Driver | No | 56 | 0.121 | 35 | 8 | 0.229 | 0 |
| CYP21A2_ENST00000643666 | CYP21A2 | P08686 | Steroid 21-hydroxylase | chr6 | GO:0004497 | Not Cancer Driver | No | 70 | 0.142 | 49 | 16 | 0.327 | 66 |
| CYP24A1 | CYP24A1 | Q07973 | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial | chr20 | GO:0004497 | Not Cancer Driver | No | 74 | 0.144 | 77 | 5 | 0.065 | 4 |
| CYP26A1 | CYP26A1 | O43174 | Cytochrome P450 26A1 | chr10 | GO:0004497 | Not Cancer Driver | No | 84 | 0.169 | 9 | 1 | 0.111 | 0 |
| CYP26B1 | CYP26B1 | Q9NR63 | Cytochrome P450 26B1 | chr2 | GO:0004497 | Not Cancer Driver | No | 113 | 0.221 | 10 | 3 | 0.3 | 2 |
| CYP26C1 | CYP26C1 | Q6V0L0 | Cytochrome P450 26C1 | chr10 | GO:0004497 | Not Cancer Driver | No | 32 | 0.061 | 56 | 6 | 0.107 | 0 |
| CYP27A1 | CYP27A1 | Q02318 | Sterol 26-hydroxylase, mitochondrial | chr2 | GO:0004497 | Not Cancer Driver | No | 69 | 0.13 | 47 | 11 | 0.234 | 7 |
| CYP27B1 | CYP27B1 | O15528 | 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial | chr12 | GO:0004497 | Not Cancer Driver | No | 71 | 0.14 | 79 | 13 | 0.165 | 18 |
| CYP2A13 | CYP2A13 | Q16696 | Cytochrome P450 2A13 | chr19 | GO:0004497 | Not Cancer Driver | No | 122 | 0.247 | 38 | 9 | 0.237 | 0 |
| CYP2A6 | CYP2A6 | P11509 | Cytochrome P450 2A6 | chr19 | GO:0004497 | Not Cancer Driver | No | 107 | 0.217 | 40 | 10 | 0.25 | 0 |
| CYP2A7 | CYP2A7 | P20853 | Cytochrome P450 2A7 | chr19 | GO:0004497 | Not Cancer Driver | No | 95 | 0.192 | 39 | 9 | 0.231 | 0 |
| CYP2B6 | CYP2B6 | P20813 | Cytochrome P450 2B6 | chr19 | GO:0004497 | Not Cancer Driver | No | 137 | 0.279 | 39 | 13 | 0.333 | 0 |
| CYP2C18 | CYP2C18 | P33260 | Cytochrome P450 2C18 | chr10 | GO:0004497 | Not Cancer Driver | No | 114 | 0.233 | 11 | 1 | 0.091 | 0 |
| CYP2C19 | CYP2C19 | P33261 | Cytochrome P450 2C19 | chr10 | GO:0004497 | Not Cancer Driver | No | 157 | 0.32 | 32 | 12 | 0.375 | 0 |
| CYP2C8 | CYP2C8 | P10632 | Cytochrome P450 2C8 | chr10 | GO:0004497 | Census, Compendium | Yes | 113 | 0.231 | 30 | 11 | 0.367 | 0 |
| CYP2C9 | CYP2C9 | P11712 | Cytochrome P450 2C9 | chr10 | GO:0004497 | Not Cancer Driver | No | 122 | 0.249 | 36 | 14 | 0.389 | 0 |
| CYP2D6_ENST00000645361 | CYP2D6 | P10635 | Cytochrome P450 2D6 | chr22 | GO:0004497 | Not Cancer Driver | No | 76 | 0.153 | 66 | 8 | 0.121 | 0 |
| CYP2D7 | CYP2D7 | A0A087X1C5 | Putative cytochrome P450 2D7 | chr22 | GO:0004497 | Not Cancer Driver | No | 74 | 0.144 | 60 | 6 | 0.1 | 0 |
| CYP2E1_ENST00000252945 | CYP2E1 | P05181 | Cytochrome P450 2E1 | chr10 | GO:0004497 | Not Cancer Driver | No | 87 | 0.176 | 21 | 6 | 0.286 | 0 |
| CYP2F1 | CYP2F1 | P24903 | Cytochrome P450 2F1 | chr19 | GO:0004497 | Not Cancer Driver | No | 85 | 0.173 | 2 | 0 | 0.0 | 0 |
| CYP2J2 | CYP2J2 | P51589 | Cytochrome P450 2J2 | chr1 | GO:0004497 | Not Cancer Driver | No | 58 | 0.116 | 63 | 6 | 0.095 | 0 |
| CYP2R1 | CYP2R1 | Q6VVX0 | Vitamin D 25-hydroxylase | chr11 | GO:0004497 | Not Cancer Driver | No | 53 | 0.106 | 5 | 1 | 0.2 | 1 |
| CYP2S1 | CYP2S1 | Q96SQ9 | Cytochrome P450 2S1 | chr19 | GO:0004497 | Not Cancer Driver | No | 75 | 0.149 | 46 | 10 | 0.217 | 0 |
| CYP2U1 | CYP2U1 | Q7Z449 | Cytochrome P450 2U1 | chr4 | GO:0004497 | Not Cancer Driver | No | 37 | 0.068 | 38 | 2 | 0.053 | 4 |
| CYP2W1 | CYP2W1 | Q8TAV3 | Cytochrome P450 2W1 | chr7 | GO:0004497 | Not Cancer Driver | No | 51 | 0.104 | 55 | 6 | 0.109 | 0 |
| CYP39A1 | CYP39A1 | Q9NYL5 | 24-hydroxycholesterol 7-alpha-hydroxylase | chr6 | GO:0004497 | Not Cancer Driver | No | 61 | 0.13 | 3 | 0 | 0.0 | 0 |
| CYP3A4 | CYP3A4 | P08684 | Cytochrome P450 3A4 | chr7 | GO:0004497 | Not Cancer Driver | No | 91 | 0.181 | 22 | 2 | 0.091 | 1 |
| CYP3A43_ENST00000354829 | CYP3A43 | Q9HB55 | Cytochrome P450 3A43 | chr7 | GO:0004497 | Not Cancer Driver | No | 79 | 0.157 | 5 | 0 | 0.0 | 0 |
| CYP3A5 | CYP3A5 | P20815 | Cytochrome P450 3A5 | chr7 | GO:0004497 | Not Cancer Driver | No | 67 | 0.133 | 38 | 5 | 0.132 | 0 |
| CYP3A7 | CYP3A7 | P24462 | Cytochrome P450 3A7 | chr7 | GO:0004497 | Not Cancer Driver | No | 91 | 0.181 | 17 | 6 | 0.353 | 0 |
| CYP46A1 | CYP46A1 | Q9Y6A2 | Cholesterol 24-hydroxylase | chr14 | GO:0004497 | Not Cancer Driver | No | 92 | 0.184 | 23 | 4 | 0.174 | 0 |
| CYP4A11 | CYP4A11 | Q02928 | Cytochrome P450 4A11 | chr1 | GO:0004497 | Not Cancer Driver | No | 131 | 0.252 | 24 | 8 | 0.333 | 0 |
| CYP4A22 | CYP4A22 | Q5TCH4 | Cytochrome P450 4A22 | chr1 | GO:0004497 | Not Cancer Driver | No | 116 | 0.224 | 26 | 6 | 0.231 | 0 |
| CYP4B1_ENST00000271153 | CYP4B1 | P13584 | Cytochrome P450 4B1 | chr1 | GO:0004497 | Not Cancer Driver | No | 124 | 0.243 | 8 | 2 | 0.25 | 0 |
| CYP4F11 | CYP4F11 | Q9HBI6 | Cytochrome P450 4F11 | chr19 | GO:0004497 | Not Cancer Driver | No | 132 | 0.252 | 11 | 2 | 0.182 | 0 |
| CYP4F12_ENST00000324632 | CYP4F12 | Q9HCS2 | Cytochrome P450 4F12 | chr19 | GO:0004497 | Not Cancer Driver | No | 138 | 0.263 | 18 | 4 | 0.222 | 0 |
| CYP4F2 | CYP4F2 | P78329 | Cytochrome P450 4F2 | chr19 | GO:0004497 | Not Cancer Driver | No | 136 | 0.262 | 17 | 3 | 0.176 | 0 |
| CYP4F22_ENST00000601005 | CYP4F22 | Q6NT55 | Ultra-long-chain fatty acid omega-hydroxylase | chr19 | GO:0004497 | Not Cancer Driver | No | 103 | 0.194 | 30 | 3 | 0.1 | 5 |
| CYP4F3 | CYP4F3 | Q08477 | Cytochrome P450 4F3 | chr19 | GO:0004497 | Not Cancer Driver | No | 125 | 0.24 | 15 | 7 | 0.467 | 0 |
| CYP4F8 | CYP4F8 | P98187 | Cytochrome P450 4F8 | chr19 | GO:0004497 | Not Cancer Driver | No | 108 | 0.208 | 28 | 10 | 0.357 | 0 |
| CYP4V2 | CYP4V2 | Q6ZWL3 | Cytochrome P450 4V2 | chr4 | GO:0004497 | Not Cancer Driver | No | 67 | 0.128 | 46 | 9 | 0.196 | 8 |
| CYP4X1 | CYP4X1 | Q8N118 | Cytochrome P450 4X1 | chr1 | GO:0004497 | Not Cancer Driver | No | 86 | 0.169 | 14 | 7 | 0.5 | 0 |
| CYP4Z1 | CYP4Z1 | Q86W10 | Cytochrome P450 4Z1 | chr1 | GO:0004497 | Not Cancer Driver | No | 106 | 0.21 | 14 | 8 | 0.571 | 0 |
| CYP51A1 | CYP51A1 | Q16850 | Lanosterol 14-alpha demethylase | chr7 | GO:0004497 | Not Cancer Driver | No | 49 | 0.096 | 7 | 2 | 0.286 | 0 |
| CYP7A1 | CYP7A1 | P22680 | Cytochrome P450 7A1 | chr8 | GO:0004497 | Not Cancer Driver | No | 109 | 0.216 | 48 | 8 | 0.167 | 0 |
| CYP7B1 | CYP7B1 | O75881 | Cytochrome P450 7B1 | chr8 | GO:0004497 | Not Cancer Driver | No | 133 | 0.263 | 0 | 0 | 0.0 | 11 |
| CYP8B1 | CYP8B1 | Q9UNU6 | 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase | chr3 | GO:0004497 | Not Cancer Driver | No | 91 | 0.182 | 5 | 1 | 0.2 | 0 |
| DBH | DBH | P09172 | Dopamine beta-hydroxylase | chr9 | GO:0004497 | Not Cancer Driver | No | 125 | 0.203 | 71 | 17 | 0.239 | 3 |
| DOHH | DOHH | Q9BU89 | Deoxyhypusine hydroxylase | chr19 | GO:0004497 | Not Cancer Driver | No | 30 | 0.099 | 56 | 6 | 0.107 | 0 |
| FAXDC2 | FAXDC2 | Q96IV6 | Fatty acid hydroxylase domain-containing protein 2 | chr5 | GO:0004497 | Not Cancer Driver | No | 39 | 0.117 | 9 | 0 | 0.0 | 0 |
| FMO1 | FMO1 | Q01740 | Dimethylaniline monooxygenase [N-oxide-forming] 1 | chr1 | GO:0004497 | Not Cancer Driver | No | 133 | 0.25 | 3 | 0 | 0.0 | 0 |
| FMO2 | FMO2 | Q99518 | Flavin-containing monooxygenase 2 | chr1 | GO:0004497 | Not Cancer Driver | No | 125 | 0.234 | 3 | 0 | 0.0 | 0 |
| FMO3 | FMO3 | P31513 | Dimethylaniline monooxygenase [N-oxide-forming] 3 | chr1 | GO:0004497 | Not Cancer Driver | No | 146 | 0.274 | 15 | 9 | 0.6 | 8 |
| FMO4 | FMO4 | P31512 | Dimethylaniline monooxygenase [N-oxide-forming] 4 | chr1 | GO:0004497 | Not Cancer Driver | No | 110 | 0.197 | 8 | 5 | 0.625 | 0 |
| FMO5 | FMO5 | P49326 | Flavin-containing monooxygenase 5 | chr1 | GO:0004497 | Not Cancer Driver | No | 82 | 0.154 | 32 | 4 | 0.125 | 0 |
| FOXRED2 | FOXRED2 | Q8IWF2 | FAD-dependent oxidoreductase domain-containing protein 2 | chr22 | GO:0004497 | Not Cancer Driver | No | 97 | 0.142 | 48 | 5 | 0.104 | 0 |
| HMOX1 | HMOX1 | P09601 | Heme oxygenase 1 | chr22 | GO:0004497 | Not Cancer Driver | No | 46 | 0.16 | 81 | 13 | 0.16 | 0 |
| HMOX2_ENST00000406590 | HMOX2 | P30519 | Heme oxygenase 2 | chr16 | GO:0004497 | Not Cancer Driver | No | 27 | 0.085 | 74 | 10 | 0.135 | 0 |
| JMJD7 | JMJD7 | P0C870 | Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 | chr15 | GO:0004497 | Not Cancer Driver | No | 40 | 0.127 | 0 | 0 | 0.0 | 0 |
| KMO | KMO | O15229 | Kynurenine 3-monooxygenase | chr1 | GO:0004497 | Not Cancer Driver | No | 77 | 0.158 | 0 | 0 | 0.0 | 0 |
| MIOX | MIOX | Q9UGB7 | Inositol oxygenase | chr22 | GO:0004497 | Not Cancer Driver | No | 48 | 0.168 | 21 | 4 | 0.19 | 0 |
| MOXD1 | MOXD1 | Q6UVY6 | DBH-like monooxygenase protein 1 | chr6 | GO:0004497 | Not Cancer Driver | No | 99 | 0.162 | 29 | 7 | 0.241 | 0 |
| MSMO1 | MSMO1 | Q15800 | Methylsterol monooxygenase 1 | chr4 | GO:0004497 | Not Cancer Driver | No | 42 | 0.143 | 4 | 0 | 0.0 | 2 |
| NLRP11 | NLRP11 | P59045 | NACHT, LRR and PYD domains-containing protein 11 | chr19 | GO:0004497 | Not Cancer Driver | No | 229 | 0.222 | 25 | 2 | 0.08 | 0 |
| NOS1_ENST00000317775 | NOS1 | P29475 | Nitric oxide synthase, brain | chr12 | GO:0004497 | Not Cancer Driver | No | 405 | 0.282 | 342 | 99 | 0.289 | 0 |
| NOS2 | NOS2 | P35228 | Nitric oxide synthase, inducible | chr17 | GO:0004497 | Not Cancer Driver | No | 207 | 0.18 | 201 | 33 | 0.164 | 0 |
| NOS3 | NOS3 | P29474 | Nitric oxide synthase, endothelial | chr7 | GO:0004497 | Not Cancer Driver | No | 168 | 0.14 | 347 | 38 | 0.11 | 0 |
| PAH | PAH | P00439 | Phenylalanine-4-hydroxylase | chr12 | GO:0004497 | Not Cancer Driver | No | 133 | 0.294 | 13 | 4 | 0.308 | 222 |
| PAM_ENST00000438793 | PAM | P19021 | Peptidyl-glycine alpha-amidating monooxygenase | chr5 | GO:0004497 | Not Cancer Driver | No | 129 | 0.133 | 254 | 37 | 0.146 | 0 |
| PCBD1 | PCBD1 | P61457 | Pterin-4-alpha-carbinolamine dehydratase | chr10 | GO:0004497 | Not Cancer Driver | No | 8 | 0.077 | 7 | 0 | 0.0 | 3 |
| PCBD2_ENST00000254908 | PCBD2 | Q9H0N5 | Pterin-4-alpha-carbinolamine dehydratase 2 | chr5 | GO:0004497 | Not Cancer Driver | No | 6 | 0.046 | 3 | 0 | 0.0 | 0 |
| PTGIS | PTGIS | Q16647 | Prostacyclin synthase | chr20 | GO:0004497 | Not Cancer Driver | No | 102 | 0.204 | 18 | 3 | 0.167 | 0 |
| SQLE | SQLE | Q14534 | Squalene monooxygenase | chr8 | GO:0004497 | Not Cancer Driver | No | 54 | 0.094 | 40 | 5 | 0.125 | 0 |
| TBXAS1_ENST00000448866 | TBXAS1 | P24557 | Thromboxane-A synthase | chr7 | GO:0004497 | Not Cancer Driver | No | 116 | 0.218 | 44 | 8 | 0.182 | 4 |
| TH | TH | P07101 | Tyrosine 3-monooxygenase | chr11 | GO:0004497 | Not Cancer Driver | No | 61 | 0.116 | 149 | 21 | 0.141 | 38 |
| TPH1 | TPH1 | P17752 | Tryptophan 5-hydroxylase 1 | chr11 | GO:0004497 | Not Cancer Driver | No | 80 | 0.18 | 14 | 3 | 0.214 | 0 |
| TPH2 | TPH2 | Q8IWU9 | Tryptophan 5-hydroxylase 2 | chr12 | GO:0004497 | Not Cancer Driver | No | 118 | 0.241 | 55 | 17 | 0.309 | 1 |
| TYR | TYR | P14679 | Tyrosinase | chr11 | GO:0004497 | Not Cancer Driver | No | 156 | 0.295 | 52 | 15 | 0.288 | 111 |
| TYRP1 | TYRP1 | P17643 | 5,6-dihydroxyindole-2-carboxylic acid oxidase | chr9 | GO:0004497 | Not Cancer Driver | No | 81 | 0.151 | 87 | 13 | 0.149 | 2 |