Total number of protein in "GO:0002218" GO term: 56
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AIM2 | AIM2 | O14862 | Interferon-inducible protein AIM2 | chr1 | GO:0002218 | Not Cancer Driver | No | 73 | 0.213 | 78 | 22 | 0.282 | 0 |
| CASP6 | CASP6 | P55212 | Caspase-6 | chr4 | GO:0002218 | Not Cancer Driver | No | 28 | 0.096 | 24 | 4 | 0.167 | 0 |
| CGAS | CGAS | Q8N884 | Cyclic GMP-AMP synthase | chr6 | GO:0002218 | Not Cancer Driver | No | 50 | 0.096 | 173 | 7 | 0.04 | 0 |
| CLEC6A | CLEC6A | Q6EIG7 | C-type lectin domain family 6 member A | chr12 | GO:0002218 | Not Cancer Driver | No | 41 | 0.196 | 7 | 0 | 0.0 | 0 |
| CLEC7A | CLEC7A | Q9BXN2 | C-type lectin domain family 7 member A | chr12 | GO:0002218 | Not Cancer Driver | No | 43 | 0.174 | 46 | 2 | 0.043 | 0 |
| CREBBP | CREBBP | Q92793 | CREB-binding protein | chr16 | GO:0002218 | Census, Compendium | Yes | 412 | 0.169 | 1796 | 247 | 0.138 | 33 |
| EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0002218 | Census, Compendium | Yes | 334 | 0.138 | 1790 | 196 | 0.109 | 1 |
| FCN1 | FCN1 | O00602 | Ficolin-1 | chr9 | GO:0002218 | Not Cancer Driver | No | 107 | 0.328 | 88 | 15 | 0.17 | 0 |
| FFAR2 | FFAR2 | O15552 | Free fatty acid receptor 2 | chr19 | GO:0002218 | Not Cancer Driver | No | 49 | 0.148 | 32 | 7 | 0.219 | 0 |
| FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0002218 | Not Cancer Driver | No | 92 | 0.171 | 70 | 13 | 0.186 | 0 |
| HCK_ENST00000534862 | HCK | P08631 | Tyrosine-protein kinase HCK | chr20 | GO:0002218 | Not Cancer Driver | No | 112 | 0.213 | 124 | 25 | 0.202 | 0 |
| HEXIM1 | HEXIM1 | O94992 | Protein HEXIM1 | chr17 | GO:0002218 | Not Cancer Driver | No | 40 | 0.111 | 352 | 40 | 0.114 | 0 |
| HMGB1_ENST00000405805 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:0002218 | Not Cancer Driver | No | 25 | 0.116 | 203 | 20 | 0.099 | 0 |
| HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | GO:0002218 | Census, Compendium | Yes | 106 | 0.145 | 257 | 37 | 0.144 | 0 |
| IFI16_ENST00000295809 | IFI16 | Q16666 | Gamma-interferon-inducible protein 16 | chr1 | GO:0002218 | Not Cancer Driver | No | 155 | 0.197 | 419 | 90 | 0.215 | 0 |
| IKBKB | IKBKB | O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | chr8 | GO:0002218 | Census, Compendium | Yes | 106 | 0.14 | 211 | 31 | 0.147 | 1 |
| KLRC2 | KLRC2 | P26717 | NKG2-C type II integral membrane protein | chr12 | GO:0002218 | Not Cancer Driver | No | 55 | 0.238 | 45 | 17 | 0.378 | 0 |
| KLRC3_ENST00000396439 | KLRC3 | Q07444 | NKG2-E type II integral membrane protein | chr12 | GO:0002218 | Not Cancer Driver | No | 37 | 0.154 | 43 | 4 | 0.093 | 0 |
| KLRC4 | KLRC4 | O43908 | NKG2-F type II integral membrane protein | chr12 | GO:0002218 | Not Cancer Driver | No | 36 | 0.228 | 45 | 7 | 0.156 | 0 |
| KLRD1 | KLRD1 | Q13241 | Natural killer cells antigen CD94 | chr12 | GO:0002218 | Not Cancer Driver | No | 37 | 0.207 | 0 | 0 | 0.0 | 0 |
| KLRK1 | KLRK1 | P26718 | NKG2-D type II integral membrane protein | chr12 | GO:0002218 | Not Cancer Driver | No | 38 | 0.176 | 0 | 0 | 0.0 | 0 |
| LILRA2 | LILRA2 | Q8N149 | Leukocyte immunoglobulin-like receptor subfamily A member 2 | chr19 | GO:0002218 | Not Cancer Driver | No | 163 | 0.337 | 137 | 44 | 0.321 | 0 |
| LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | GO:0002218 | Census | Yes | 95 | 0.186 | 84 | 12 | 0.143 | 0 |
| MAP3K7 | MAP3K7 | O43318 | Mitogen-activated protein kinase kinase kinase 7 | chr6 | GO:0002218 | Not Cancer Driver | No | 104 | 0.172 | 333 | 66 | 0.198 | 6 |
| MATR3_ENST00000509990 | MATR3 | P43243 | Matrin-3 | chr5 | GO:0002218 | Not Cancer Driver | No | 98 | 0.116 | 611 | 68 | 0.111 | 3 |
| MAVS | MAVS | Q7Z434 | Mitochondrial antiviral-signaling protein | chr20 | GO:0002218 | Not Cancer Driver | No | 70 | 0.13 | 411 | 58 | 0.141 | 0 |
| MBL2 | MBL2 | P11226 | Mannose-binding protein C | chr10 | GO:0002218 | Not Cancer Driver | No | 63 | 0.254 | 122 | 32 | 0.262 | 0 |
| MNDA | MNDA | P41218 | Myeloid cell nuclear differentiation antigen | chr1 | GO:0002218 | Not Cancer Driver | No | 180 | 0.442 | 172 | 76 | 0.442 | 0 |
| NLRC4_ENST00000360906 | NLRC4 | Q9NPP4 | NLR family CARD domain-containing protein 4 | chr2 | GO:0002218 | Not Cancer Driver | No | 205 | 0.2 | 15 | 2 | 0.133 | 3 |
| NONO | NONO | Q15233 | Non-POU domain-containing octamer-binding protein | chrX | GO:0002218 | Census, Compendium | Yes | 101 | 0.214 | 349 | 64 | 0.183 | 0 |
| PAK1_ENST00000356341 | PAK1 | Q13153 | Serine/threonine-protein kinase PAK 1 | chr11 | GO:0002218 | Not Cancer Driver | No | 57 | 0.105 | 299 | 30 | 0.1 | 2 |
| PAK2 | PAK2 | Q13177 | Serine/threonine-protein kinase PAK 2 | chr3 | GO:0002218 | Compendium | Yes | 89 | 0.17 | 242 | 49 | 0.202 | 0 |
| PAK3_ENST00000262836 | PAK3 | O75914 | Serine/threonine-protein kinase PAK 3 | chrX | GO:0002218 | Not Cancer Driver | No | 127 | 0.227 | 286 | 64 | 0.224 | 2 |
| PLCG2 | PLCG2 | P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | chr16 | GO:0002218 | Not Cancer Driver | No | 248 | 0.196 | 142 | 30 | 0.211 | 1 |
| PQBP1_ENST00000376563 | PQBP1 | O60828 | Polyglutamine-binding protein 1 | chrX | GO:0002218 | Not Cancer Driver | No | 42 | 0.158 | 233 | 38 | 0.163 | 1 |
| PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0002218 | Not Cancer Driver | No | 538 | 0.13 | 421 | 61 | 0.145 | 2 |
| PSPC1_ENST00000619300 | PSPC1 | Q8WXF1 | Paraspeckle component 1 | chr13 | GO:0002218 | Not Cancer Driver | No | 97 | 0.185 | 367 | 81 | 0.221 | 0 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0002218 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| PYHIN1 | PYHIN1 | Q6K0P9 | Pyrin and HIN domain-containing protein 1 | chr1 | GO:0002218 | Not Cancer Driver | No | 174 | 0.354 | 291 | 99 | 0.34 | 0 |
| RBM14 | RBM14 | Q96PK6 | RNA-binding protein 14 | chr11 | GO:0002218 | Not Cancer Driver | No | 99 | 0.148 | 350 | 59 | 0.169 | 0 |
| SFPQ | SFPQ | P23246 | Splicing factor, proline- and glutamine-rich | chr1 | GO:0002218 | Census | Yes | 59 | 0.083 | 595 | 48 | 0.081 | 0 |
| SIN3A_ENST00000360439 | SIN3A | Q96ST3 | Paired amphipathic helix protein Sin3a | chr15 | GO:0002218 | Compendium | Yes | 172 | 0.135 | 617 | 73 | 0.118 | 0 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0002218 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| SYK_ENST00000375746 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0002218 | Census | Yes | 96 | 0.151 | 131 | 27 | 0.206 | 5 |
| TBK1 | TBK1 | Q9UHD2 | Serine/threonine-protein kinase TBK1 | chr12 | GO:0002218 | Not Cancer Driver | No | 101 | 0.139 | 42 | 5 | 0.119 | 12 |
| TLR4_ENST00000355622 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:0002218 | Not Cancer Driver | No | 292 | 0.348 | 0 | 0 | 0.0 | 0 |
| TMEM173 | STING1 | Q86WV6 | Stimulator of interferon genes protein | chr5 | GO:0002218 | Not Cancer Driver | No | 46 | 0.121 | 66 | 13 | 0.197 | 3 |
| TOMM70 | TOMM70 | O94826 | Mitochondrial import receptor subunit TOM70 | chr3 | GO:0002218 | Not Cancer Driver | No | 59 | 0.097 | 140 | 8 | 0.057 | 0 |
| TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:0002218 | Not Cancer Driver | No | 67 | 0.128 | 62 | 7 | 0.113 | 0 |
| TRIM5 | TRIM5 | Q9C035 | Tripartite motif-containing protein 5 | chr11 | GO:0002218 | Not Cancer Driver | No | 71 | 0.144 | 77 | 11 | 0.143 | 0 |
| TYROBP | TYROBP | O43914 | TYRO protein tyrosine kinase-binding protein | chr19 | GO:0002218 | Not Cancer Driver | No | 24 | 0.212 | 28 | 8 | 0.286 | 0 |
| XRCC5_ENST00000392132 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | GO:0002218 | Not Cancer Driver | No | 87 | 0.119 | 118 | 11 | 0.093 | 0 |
| XRCC6 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | GO:0002218 | Not Cancer Driver | No | 66 | 0.108 | 140 | 12 | 0.086 | 0 |
| ZBP1 | ZBP1 | Q9H171 | Z-DNA-binding protein 1 | chr20 | GO:0002218 | Not Cancer Driver | No | 97 | 0.226 | 385 | 80 | 0.208 | 0 |
| ZCCHC3 | ZCCHC3 | Q9NUD5 | Zinc finger CCHC domain-containing protein 3 | chr20 | GO:0002218 | Not Cancer Driver | No | 28 | 0.069 | 160 | 1 | 0.006 | 0 |
| ZNFX1_ENST00000371752 | ZNFX1 | Q9P2E3 | NFX1-type zinc finger-containing protein 1 | chr20 | GO:0002218 | Not Cancer Driver | No | 228 | 0.119 | 354 | 49 | 0.138 | 0 |