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Total number of protein in "GO:0002020" GO term:  134

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A2M A2M P01023 Alpha-2-macroglobulin chr12 GO:0002020 Not Cancer Driver No 260 0.176 144 22 0.153 0
A2ML1 A2ML1 A8K2U0 Alpha-2-macroglobulin-like protein 1 chr12 GO:0002020 Not Cancer Driver No 269 0.185 97 22 0.227 0
ADAMTS4 ADAMTS4 O75173 A disintegrin and metalloproteinase with thrombospondin motifs 4 chr1 GO:0002020 Not Cancer Driver No 134 0.16 159 27 0.17 0
ADAMTSL4_ENST00000369038 ADAMTSL4 Q6UY14 ADAMTS-like protein 4 chr1 GO:0002020 Not Cancer Driver No 156 0.145 563 78 0.139 0
ADRM1 ADRM1 Q16186 Proteasomal ubiquitin receptor ADRM1 chr20 GO:0002020 Not Cancer Driver No 49 0.12 296 40 0.135 0
ALPI ALPI P09923 Intestinal-type alkaline phosphatase chr2 GO:0002020 Not Cancer Driver No 94 0.178 157 36 0.229 0
AMFR AMFR Q9UKV5 E3 ubiquitin-protein ligase AMFR chr16 GO:0002020 Not Cancer Driver No 73 0.114 229 30 0.131 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 GO:0002020 Not Cancer Driver No 49 0.145 20 4 0.2 0
ANXA9 ANXA9 O76027 Annexin A9 chr1 GO:0002020 Not Cancer Driver No 52 0.151 42 7 0.167 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 GO:0002020 Not Cancer Driver No 66 0.119 23 5 0.217 2
ATP9A ATP9A O75110 Probable phospholipid-transporting ATPase IIA chr20 GO:0002020 Not Cancer Driver No 175 0.167 69 18 0.261 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0002020 Not Cancer Driver No 98 0.087 861 79 0.092 0
BANK1 BANK1 Q8NDB2 B-cell scaffold protein with ankyrin repeats chr4 GO:0002020 Not Cancer Driver No 150 0.191 394 73 0.185 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0002020 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL2L10_ENST00000260442 BCL2L10 Q9HD36 Bcl-2-like protein 10 chr15 GO:0002020 Not Cancer Driver No 10 0.049 34 1 0.029 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0002020 Census, Compendium Yes 24 0.1 72 5 0.069 0
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 GO:0002020 Not Cancer Driver No 81 0.207 0 0 0.0 0
BFAR BFAR Q9NZS9 Bifunctional apoptosis regulator chr16 GO:0002020 Not Cancer Driver No 56 0.124 30 1 0.033 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0002020 Not Cancer Driver No 65 0.11 456 42 0.092 5
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:0002020 Census, Compendium Yes 457 0.134 1542 225 0.146 46
CARD16 CARD16 Q5EG05 Caspase recruitment domain-containing protein 16 chr11 GO:0002020 Not Cancer Driver No 36 0.183 23 7 0.304 0
CARD17 CARD17 Q5XLA6 Caspase recruitment domain-containing protein 17 chr11 GO:0002020 Not Cancer Driver No 24 0.218 22 7 0.318 0
CARD18 CARD18 P57730 Caspase recruitment domain-containing protein 18 chr11 GO:0002020 Not Cancer Driver No 24 0.267 14 1 0.071 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0002020 Census Yes 32 0.116 62 5 0.081 0
CCBE1 CCBE1 Q6UXH8 Collagen and calcium-binding EGF domain-containing protein 1 chr18 GO:0002020 Not Cancer Driver No 92 0.227 227 58 0.256 5
CD177 CD177 Q8N6Q3 CD177 antigen chr19 GO:0002020 Not Cancer Driver No 71 0.162 79 26 0.329 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0002020 Census Yes 42 0.191 18 10 0.556 0
CD70_ENST00000245903 CD70 P32970 CD70 antigen chr19 GO:0002020 Not Cancer Driver No 33 0.171 11 2 0.182 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0002020 Not Cancer Driver No 35 0.114 103 16 0.155 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0002020 Not Cancer Driver No 40 0.083 44 2 0.045 0
CHL1_ENST00000397491 CHL1 O00533 Neural cell adhesion molecule L1-like protein chr3 GO:0002020 Not Cancer Driver No 348 0.288 415 121 0.292 0
CHMP3 CHMP3 Q9Y3E7 Charged multivesicular body protein 3 chr2 GO:0002020 Not Cancer Driver No 25 0.113 137 13 0.095 0
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 GO:0002020 Census, Compendium Yes 190 0.113 71 6 0.085 1
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0002020 Census, Compendium Yes 247 0.169 1212 214 0.177 148
COL1A2 COL1A2 P08123 Collagen alpha-2(I) chain chr7 GO:0002020 Not Cancer Driver No 372 0.272 1159 329 0.284 83
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0002020 Census Yes 402 0.274 1182 337 0.285 103
COMP COMP P49747 Cartilage oligomeric matrix protein chr19 GO:0002020 Not Cancer Driver No 97 0.128 306 52 0.17 61
CRADD_ENST00000332896 CRADD P78560 Death domain-containing protein CRADD chr12 GO:0002020 Not Cancer Driver No 35 0.176 45 5 0.111 1
CST3_ENST00000376925 CST3 P01034 Cystatin-C chr20 GO:0002020 Not Cancer Driver No 17 0.116 31 1 0.032 2
CSTA CSTA P01040 Cystatin-A chr3 GO:0002020 Not Cancer Driver No 16 0.163 54 9 0.167 0
CSTB CSTB P04080 Cystatin-B chr21 GO:0002020 Not Cancer Driver No 7 0.071 40 0 0.0 1
CTSG CTSG P08311 Cathepsin G chr14 GO:0002020 Not Cancer Driver No 65 0.255 80 29 0.362 0
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 GO:0002020 Not Cancer Driver No 28 0.112 11 1 0.091 0
DERL2 DERL2 Q9GZP9 Derlin-2 chr17 GO:0002020 Not Cancer Driver No 19 0.079 15 1 0.067 0
DERL3_ENST00000318109 DERL3 Q96Q80 Derlin-3 chr22 GO:0002020 Not Cancer Driver No 18 0.077 18 1 0.056 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0002020 Not Cancer Driver No 151 0.197 8 1 0.125 0
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 GO:0002020 Not Cancer Driver No 97 0.135 437 58 0.133 0
ECM1_ENST00000369047 ECM1 Q16610 Extracellular matrix protein 1 chr1 GO:0002020 Not Cancer Driver No 91 0.169 219 28 0.128 1
ELANE_ENST00000263621 ELANE P08246 Neutrophil elastase chr19 GO:0002020 Not Cancer Driver No 39 0.146 18 3 0.167 89
F3 F3 P13726 Tissue factor chr1 GO:0002020 Not Cancer Driver No 28 0.095 61 7 0.115 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0002020 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAP FAP Q12884 Prolyl endopeptidase FAP chr2 GO:0002020 Not Cancer Driver No 158 0.208 6 2 0.333 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0002020 Not Cancer Driver No 43 0.101 122 15 0.123 0
FN1 FN1 P02751 Fibronectin chr2 GO:0002020 Compendium Yes 394 0.159 1243 185 0.149 8
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0002020 Not Cancer Driver No 93 0.117 283 35 0.124 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0002020 Not Cancer Driver No 56 0.133 146 13 0.089 0
IL1R1 IL1R1 P14778 Interleukin-1 receptor type 1 chr2 GO:0002020 Not Cancer Driver No 77 0.135 59 8 0.136 0
INS INS P01308 Insulin chr11 GO:0002020 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSL3_ENST00000317306 INSL3 P51460 Insulin-like 3 chr19 GO:0002020 Not Cancer Driver No 18 0.137 34 12 0.353 3
ITGA3 ITGA3 P26006 Integrin alpha-3 chr17 GO:0002020 Not Cancer Driver No 106 0.101 129 18 0.14 3
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0002020 Census Yes 153 0.146 92 9 0.098 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0002020 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0002020 Not Cancer Driver No 124 0.157 66 5 0.076 30
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0002020 Census, Compendium Yes 226 0.232 83 33 0.398 21
LCOR LCOR Q96JN0 Ligand-dependent corepressor chr10 GO:0002020 Not Cancer Driver No 54 0.125 388 46 0.119 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0002020 Not Cancer Driver No 119 0.138 63 3 0.048 104
LONP2 LONP2 Q86WA8 Lon protease homolog 2, peroxisomal chr16 GO:0002020 Not Cancer Driver No 116 0.136 163 26 0.16 0
MAGEA3 MAGEA3 P43357 Melanoma-associated antigen 3 chrX GO:0002020 Not Cancer Driver No 79 0.252 103 18 0.175 0
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0002020 Census, Compendium Yes 75 0.091 139 12 0.086 1
MARCH6 MARCHF6 O60337 E3 ubiquitin-protein ligase MARCHF6 chr5 GO:0002020 Not Cancer Driver No 114 0.125 114 13 0.114 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0002020 Not Cancer Driver No 52 0.171 304 52 0.171 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0002020 Not Cancer Driver No 4 0.035 0 0 0.0 0
NDUFS7 NDUFS7 O75251 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial chr19 GO:0002020 Not Cancer Driver No 36 0.169 30 3 0.1 1
NFRKB_ENST00000446488 NFRKB Q6P4R8 Nuclear factor related to kappa-B-binding protein chr11 GO:0002020 Not Cancer Driver No 128 0.099 838 74 0.088 0
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 GO:0002020 Not Cancer Driver No 205 0.2 15 2 0.133 3
NLRP7_ENST00000590030 NLRP7 Q8WX94 NACHT, LRR and PYD domains-containing protein 7 chr19 GO:0002020 Not Cancer Driver No 300 0.306 71 20 0.282 9
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:0002020 Not Cancer Driver No 20 0.096 179 17 0.095 2
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0002020 Not Cancer Driver No 155 0.189 117 18 0.154 1
OS9 OS9 Q13438 Protein OS-9 chr12 GO:0002020 Not Cancer Driver No 72 0.108 451 49 0.109 0
PANX1 PANX1 Q96RD7 Pannexin-1 chr11 GO:0002020 Not Cancer Driver No 54 0.127 45 7 0.156 2
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0002020 Not Cancer Driver No 11 0.058 30 0 0.0 5
PDZD3_ENST00000531114 PDZD3 Q86UT5 Na(+)/H(+) exchange regulatory cofactor NHE-RF4 chr11 GO:0002020 Not Cancer Driver No 58 0.102 199 19 0.095 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0002020 Not Cancer Driver No 57 0.098 99 13 0.131 23
POLG_ENST00000442287 POLG P54098 DNA polymerase subunit gamma-1 chr15 GO:0002020 Census Yes 139 0.112 421 42 0.1 73
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0002020 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRNP PRNP P04156 Major prion protein chr20 GO:0002020 Not Cancer Driver No 36 0.142 115 7 0.061 18
PSAP PSAP P07602 Prosaposin chr10 GO:0002020 Not Cancer Driver No 59 0.113 28 2 0.071 8
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0002020 Census, Compendium Yes 505 1.253 76 4 0.053 41
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0002020 Not Cancer Driver No 16 0.082 39 4 0.103 0
PZP PZP P20742 Pregnancy zone protein chr12 GO:0002020 Not Cancer Driver No 279 0.188 101 21 0.208 0
RAD23A RAD23A P54725 UV excision repair protein RAD23 homolog A chr19 GO:0002020 Not Cancer Driver No 50 0.138 283 41 0.145 0
RFFL_ENST00000394597 RFFL Q8WZ73 E3 ubiquitin-protein ligase rififylin chr17 GO:0002020 Not Cancer Driver No 50 0.138 150 21 0.14 0
RHBDD2 RHBDD2 Q6NTF9 Rhomboid domain-containing protein 2 chr7 GO:0002020 Not Cancer Driver No 48 0.132 120 23 0.192 0
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:0002020 Not Cancer Driver No 58 0.112 225 21 0.093 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0002020 Not Cancer Driver No 63 0.117 143 20 0.14 0
RNF139 RNF139 Q8WU17 E3 ubiquitin-protein ligase RNF139 chr8 GO:0002020 Not Cancer Driver No 76 0.114 68 4 0.059 0
SART3 SART3 Q15020 Squamous cell carcinoma antigen recognized by T-cells 3 chr12 GO:0002020 Not Cancer Driver No 101 0.105 404 45 0.111 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:0002020 Not Cancer Driver No 7 0.037 122 6 0.049 0
SELL SELL P14151 L-selectin chr1 GO:0002020 Not Cancer Driver No 68 0.183 20 3 0.15 0
SEMG2 SEMG2 Q02383 Semenogelin-2 chr20 GO:0002020 Not Cancer Driver No 147 0.253 561 145 0.258 0
SERPINA1 SERPINA1 P01009 Alpha-1-antitrypsin chr14 GO:0002020 Not Cancer Driver No 66 0.158 38 7 0.184 0
SERPINA5_ENST00000554276 SERPINA5 P05154 Plasma serine protease inhibitor chr14 GO:0002020 Not Cancer Driver No 103 0.254 24 17 0.708 0
SERPINB13_ENST00000344731 SERPINB13 Q9UIV8 Serpin B13 chr18 GO:0002020 Not Cancer Driver No 84 0.215 55 16 0.291 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 GO:0002020 Not Cancer Driver No 142 0.364 47 28 0.596 0
SERPINB4 SERPINB4 P48594 Serpin B4 chr18 GO:0002020 Not Cancer Driver No 120 0.308 48 18 0.375 0
SERPINB6_ENST00000644388 SERPINB6 P35237 Serpin B6 chr6 GO:0002020 Not Cancer Driver No 47 0.125 8 0 0.0 0
SERPINB9 SERPINB9 P50453 Serpin B9 chr6 GO:0002020 Not Cancer Driver No 64 0.17 22 2 0.091 0
SERPINC1 SERPINC1 P01008 Antithrombin-III chr1 GO:0002020 Not Cancer Driver No 84 0.181 29 8 0.276 84
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0002020 Not Cancer Driver No 78 0.194 7 2 0.286 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0002020 Not Cancer Driver No 62 0.126 112 21 0.188 1
SH3PXD2A_ENST00000369774 SH3PXD2A Q5TCZ1 SH3 and PX domain-containing protein 2A chr10 GO:0002020 Not Cancer Driver No 141 0.124 797 101 0.127 0
SLC2A13 SLC2A13 Q96QE2 Proton myo-inositol cotransporter chr12 GO:0002020 Not Cancer Driver No 79 0.122 52 4 0.077 0
SLC6A3 SLC6A3 Q01959 Sodium-dependent dopamine transporter chr5 GO:0002020 Not Cancer Driver No 150 0.242 31 8 0.258 2
SPATA2_ENST00000289431 SPATA2 Q9UM82 Spermatogenesis-associated protein 2 chr20 GO:0002020 Not Cancer Driver No 70 0.135 235 39 0.166 0
SRI SRI P30626 Sorcin chr7 GO:0002020 Not Cancer Driver No 15 0.076 32 2 0.062 0
STIM1_ENST00000300737 STIM1 Q13586 Stromal interaction molecule 1 chr11 GO:0002020 Not Cancer Driver No 70 0.102 387 45 0.116 13
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 GO:0002020 Not Cancer Driver No 10 0.099 76 7 0.092 0
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 GO:0002020 Not Cancer Driver No 63 0.102 284 32 0.113 0
THAP5 THAP5 Q7Z6K1 THAP domain-containing protein 5 chr7 GO:0002020 Not Cancer Driver No 42 0.106 218 25 0.115 0
TIMP1 TIMP1 P01033 Metalloproteinase inhibitor 1 chrX GO:0002020 Not Cancer Driver No 25 0.121 0 0 0.0 0
TIMP2 TIMP2 P16035 Metalloproteinase inhibitor 2 chr17 GO:0002020 Not Cancer Driver No 31 0.141 6 2 0.333 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:0002020 Not Cancer Driver No 43 0.204 3 1 0.333 5
TIMP4 TIMP4 Q99727 Metalloproteinase inhibitor 4 chr3 GO:0002020 Not Cancer Driver No 30 0.134 8 2 0.25 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0002020 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0002020 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 GO:0002020 Not Cancer Driver No 55 0.118 174 17 0.098 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0002020 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRIP4 TRIP4 Q15650 Activating signal cointegrator 1 chr15 GO:0002020 Not Cancer Driver No 71 0.122 176 27 0.153 0
TTN_ENST00000615779 TTN Q8WZ42 Titin chr2 GO:0002020 Not Cancer Driver No 7917 0.23 12926 2861 0.221 10
TWNK TWNK Q96RR1 Twinkle mtDNA helicase chr10 GO:0002020 Not Cancer Driver No 95 0.139 135 11 0.081 38
TYSND1 TYSND1 Q2T9J0 Peroxisomal leader peptide-processing protease chr10 GO:0002020 Not Cancer Driver No 40 0.071 135 12 0.089 0
UBC UBC P0CG48 Polyubiquitin-C chr12 GO:0002020 Not Cancer Driver No 97 0.142 312 53 0.17 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0002020 Not Cancer Driver No 88 0.109 186 16 0.086 16
VWF VWF P04275 von Willebrand factor chr12 GO:0002020 Not Cancer Driver No 456 0.162 91 16 0.176 43