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Total number of protein in "GO:0001708" GO term:  78

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0001708 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APC2_ENST00000233607 APC2 O95996 Adenomatous polyposis coli protein 2 chr19 GO:0001708 Not Cancer Driver No 117 0.051 1725 78 0.045 0
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0001708 Not Cancer Driver No 33 0.14 182 24 0.132 0
ATOH1 ATOH1 Q92858 Transcription factor ATOH1 chr4 GO:0001708 Not Cancer Driver No 63 0.178 327 55 0.168 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0001708 Census, Compendium Yes 415 0.531 288 301 1.045 14
DBX1 DBX1 A6NMT0 Homeobox protein DBX1 chr11 GO:0001708 Not Cancer Driver No 46 0.134 238 33 0.139 0
DHH DHH O43323 Desert hedgehog protein chr12 GO:0001708 Not Cancer Driver No 36 0.091 57 7 0.123 1
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0001708 Not Cancer Driver No 115 0.159 145 24 0.166 1
DMRT3 DMRT3 Q9NQL9 Doublesex- and mab-3-related transcription factor 3 chr9 GO:0001708 Not Cancer Driver No 94 0.199 345 71 0.206 0
DMRTA2_ENST00000418121 DMRTA2 Q96SC8 Doublesex- and mab-3-related transcription factor A2 chr1 GO:0001708 Not Cancer Driver No 25 0.046 325 19 0.058 0
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 GO:0001708 Not Cancer Driver No 142 0.117 585 71 0.121 0
EOMES_ENST00000295743 EOMES O95936 Eomesodermin homolog chr3 GO:0001708 Not Cancer Driver No 82 0.12 436 50 0.115 0
EYA1_ENST00000647540 EYA1 Q99502 Eyes absent homolog 1 chr8 GO:0001708 Not Cancer Driver No 168 0.284 341 99 0.29 15
EYA2 EYA2 O00167 Eyes absent homolog 2 chr20 GO:0001708 Not Cancer Driver No 107 0.199 204 50 0.245 0
FEV FEV Q99581 Protein FEV chr2 GO:0001708 Census Yes 15 0.063 55 0 0.0 0
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 GO:0001708 Not Cancer Driver No 71 0.172 160 25 0.156 0
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 GO:0001708 Census, Compendium Yes 100 0.212 295 53 0.18 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0001708 Compendium Yes 70 0.153 258 34 0.132 0
GSC GSC P56915 Homeobox protein goosecoid chr14 GO:0001708 Not Cancer Driver No 17 0.066 109 11 0.101 0
GSX2 GSX2 Q9BZM3 GS homeobox 2 chr4 GO:0001708 Not Cancer Driver No 44 0.145 210 26 0.124 1
HOXA11 HOXA11 P31270 Homeobox protein Hox-A11 chr7 GO:0001708 Census, Compendium Yes 37 0.118 205 26 0.127 0
HOXA13 HOXA13 P31271 Homeobox protein Hox-A13 chr7 GO:0001708 Census Yes 37 0.095 171 22 0.129 4
HOXC10 HOXC10 Q9NYD6 Homeobox protein Hox-C10 chr12 GO:0001708 Not Cancer Driver No 62 0.181 266 48 0.18 0
HOXD10 HOXD10 P28358 Homeobox protein Hox-D10 chr2 GO:0001708 Not Cancer Driver No 74 0.218 230 55 0.239 1
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0001708 Not Cancer Driver No 58 0.141 111 15 0.135 6
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0001708 Not Cancer Driver No 85 0.244 180 41 0.228 0
ISL2 ISL2 Q96A47 Insulin gene enhancer protein ISL-2 chr15 GO:0001708 Not Cancer Driver No 42 0.117 167 16 0.096 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0001708 Not Cancer Driver No 103 0.129 84 10 0.119 0
LHX3_ENST00000371748 LHX3 Q9UBR4 LIM/homeobox protein Lhx3 chr9 GO:0001708 Not Cancer Driver No 38 0.096 232 14 0.06 2
MGA MGA Q8IWI9 MAX gene-associated protein chr15 GO:0001708 Compendium Yes 341 0.111 2317 259 0.112 0
MNX1 MNX1 P50219 Motor neuron and pancreas homeobox protein 1 chr7 GO:0001708 Census Yes 34 0.085 297 30 0.101 11
MYL2 MYL2 P10916 Myosin regulatory light chain 2, ventricular/cardiac muscle isoform chr12 GO:0001708 Not Cancer Driver No 44 0.265 34 8 0.235 6
MYT1L MYT1L Q9UL68 Myelin transcription factor 1-like protein chr2 GO:0001708 Not Cancer Driver No 361 0.304 1090 337 0.309 0
NANOG NANOG Q9H9S0 Homeobox protein NANOG chr12 GO:0001708 Not Cancer Driver No 46 0.151 169 35 0.207 0
NKX2-2 NKX2-2 O95096 Homeobox protein Nkx-2.2 chr20 GO:0001708 Not Cancer Driver No 84 0.308 206 65 0.316 0
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0001708 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0001708 Census, Compendium Yes 363 0.142 686 87 0.127 3
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0001708 Compendium Yes 146 0.158 211 31 0.147 0
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0001708 Census, Compendium Yes 249 0.297 57 21 0.368 0
OLIG2_ENST00000382357 OLIG2 Q13516 Oligodendrocyte transcription factor 2 chr21 GO:0001708 Census Yes 37 0.115 256 37 0.145 0
OLIG3 OLIG3 Q7RTU3 Oligodendrocyte transcription factor 3 chr6 GO:0001708 Not Cancer Driver No 50 0.184 186 39 0.21 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0001708 Not Cancer Driver No 62 0.149 296 48 0.162 23
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0001708 Not Cancer Driver No 72 0.171 337 56 0.166 38
POU3F2 POU3F2 P20265 POU domain, class 3, transcription factor 2 chr6 GO:0001708 Not Cancer Driver No 52 0.117 361 36 0.1 0
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0001708 Not Cancer Driver No 51 0.122 273 34 0.125 1
POU5F1 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 GO:0001708 Census Yes 36 0.1 186 12 0.065 0
PRDM14 PRDM14 Q9GZV8 PR domain zinc finger protein 14 chr8 GO:0001708 Not Cancer Driver No 122 0.214 179 37 0.207 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0001708 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0001708 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTCH2 PTCH2 Q9Y6C5 Protein patched homolog 2 chr1 GO:0001708 Not Cancer Driver No 159 0.132 130 15 0.115 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0001708 Not Cancer Driver No 49 0.098 151 19 0.126 2
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0001708 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0001708 Census, Compendium Yes 49 0.173 144 25 0.174 8
SIX2 SIX2 Q9NPC8 Homeobox protein SIX2 chr2 GO:0001708 Census Yes 53 0.182 151 21 0.139 0
SMO SMO Q99835 Smoothened homolog chr7 GO:0001708 Census, Compendium Yes 112 0.142 241 27 0.112 1
SOX1 SOX1 O00570 Transcription factor SOX-1 chr13 GO:0001708 Not Cancer Driver No 26 0.066 304 25 0.082 0
SOX17 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 GO:0001708 Compendium Yes 81 0.196 378 59 0.156 2
SOX18 SOX18 P35713 Transcription factor SOX-18 chr20 GO:0001708 Not Cancer Driver No 10 0.026 321 10 0.031 2
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 GO:0001708 Census Yes 39 0.123 312 39 0.125 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0001708 Compendium Yes 86 0.169 495 82 0.166 18
TBR1 TBR1 Q16650 T-box brain protein 1 chr2 GO:0001708 Not Cancer Driver No 88 0.129 413 56 0.136 5
TBX10 TBX10 O75333 T-box transcription factor TBX10 chr11 GO:0001708 Not Cancer Driver No 54 0.14 150 18 0.12 0
TBX15 TBX15 Q96SF7 T-box transcription factor TBX15 chr1 GO:0001708 Not Cancer Driver No 141 0.234 388 88 0.227 0
TBX18 TBX18 O95935 T-box transcription factor TBX18 chr6 GO:0001708 Not Cancer Driver No 156 0.257 356 94 0.264 2
TBX19 TBX19 O60806 T-box transcription factor TBX19 chr1 GO:0001708 Not Cancer Driver No 85 0.19 233 39 0.167 1
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0001708 Not Cancer Driver No 35 0.088 197 12 0.061 4
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0001708 Not Cancer Driver No 74 0.104 401 36 0.09 1
TBX20 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 GO:0001708 Not Cancer Driver No 117 0.262 201 54 0.269 2
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0001708 Not Cancer Driver No 70 0.131 348 50 0.144 0
TBX22 TBX22 Q9Y458 T-box transcription factor TBX22 chrX GO:0001708 Not Cancer Driver No 163 0.313 202 64 0.317 6
TBX3 TBX3 O15119 T-box transcription factor TBX3 chr12 GO:0001708 Census, Compendium Yes 123 0.166 352 57 0.162 2
TBX4_ENST00000240335 TBX4 P57082 T-box transcription factor TBX4 chr17 GO:0001708 Not Cancer Driver No 99 0.182 318 69 0.217 2
TBX5 TBX5 Q99593 T-box transcription factor TBX5 chr12 GO:0001708 Not Cancer Driver No 155 0.299 351 113 0.322 5
TBX6 TBX6 O95947 T-box transcription factor TBX6 chr16 GO:0001708 Not Cancer Driver No 44 0.101 253 25 0.099 0
TBXT TBXT O15178 T-box transcription factor T chr6 GO:0001708 Not Cancer Driver No 110 0.253 253 69 0.273 1
TEAD4 TEAD4 Q15561 Transcriptional enhancer factor TEF-3 chr12 GO:0001708 Not Cancer Driver No 72 0.166 171 34 0.199 0
TENM4 TENM4 Q6N022 Teneurin-4 chr11 GO:0001708 Not Cancer Driver No 492 0.178 498 63 0.127 3
TLX3 TLX3 O43711 T-cell leukemia homeobox protein 3 chr5 GO:0001708 Census Yes 40 0.137 179 24 0.134 0