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Total number of protein in "GO:0000776" GO term:  137

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AHCTF1 AHCTF1 Q8WYP5 Protein ELYS chr1 GO:0000776 Not Cancer Driver No 296 0.131 1060 130 0.123 0
ANAPC16 ANAPC16 Q96DE5 Anaphase-promoting complex subunit 16 chr10 GO:0000776 Not Cancer Driver No 11 0.1 42 4 0.095 0
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0000776 Census, Compendium Yes 412 0.145 2406 345 0.143 22
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0000776 Not Cancer Driver No 51 0.148 63 8 0.127 0
BIRC5_ENST00000350051 BIRC5 O15392 Baculoviral IAP repeat-containing protein 5 chr17 GO:0000776 Not Cancer Driver No 20 0.141 49 6 0.122 0
BUB1 BUB1 O43683 Mitotic checkpoint serine/threonine-protein kinase BUB1 chr2 GO:0000776 Not Cancer Driver No 139 0.128 466 64 0.137 0
BUB1B BUB1B O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta chr15 GO:0000776 Census Yes 96 0.091 480 35 0.073 7
BUB3 BUB3 O43684 Mitotic checkpoint protein BUB3 chr10 GO:0000776 Not Cancer Driver No 46 0.14 60 6 0.1 0
CBX5 CBX5 P45973 Chromobox protein homolog 5 chr12 GO:0000776 Not Cancer Driver No 21 0.11 116 12 0.103 0
CDT1 CDT1 Q9H211 DNA replication factor Cdt1 chr16 GO:0000776 Not Cancer Driver No 60 0.11 377 35 0.093 5
CENPA CENPA P49450 Histone H3-like centromeric protein A chr2 GO:0000776 Not Cancer Driver No 15 0.107 50 4 0.08 0
CENPC CENPC Q03188 Centromere protein C chr4 GO:0000776 Not Cancer Driver No 96 0.102 790 84 0.106 0
CENPE CENPE Q02224 Centromere-associated protein E chr4 GO:0000776 Not Cancer Driver No 343 0.127 1620 228 0.141 2
CENPF CENPF P49454 Centromere protein F chr1 GO:0000776 Not Cancer Driver No 387 0.124 2136 260 0.122 0
CENPH CENPH Q9H3R5 Centromere protein H chr5 GO:0000776 Not Cancer Driver No 28 0.113 85 7 0.082 0
CENPI_ENST00000423383 CENPI Q92674 Centromere protein I chrX GO:0000776 Not Cancer Driver No 107 0.142 82 7 0.085 0
CENPK_ENST00000514814 CENPK Q9BS16 Centromere protein K chr5 GO:0000776 Not Cancer Driver No 28 0.104 91 8 0.088 0
CENPM CENPM Q9NSP4 Centromere protein M chr22 GO:0000776 Not Cancer Driver No 12 0.067 1 0 0.0 0
CENPN_ENST00000305850 CENPN Q96H22 Centromere protein N chr16 GO:0000776 Not Cancer Driver No 47 0.139 22 5 0.227 0
CENPS CENPS Q8N2Z9 Centromere protein S chr1 GO:0000776 Not Cancer Driver No 16 0.116 65 7 0.108 0
CENPT_ENST00000440851 CENPT Q96BT3 Centromere protein T chr16 GO:0000776 Not Cancer Driver No 59 0.105 468 55 0.118 0
CENPU CENPU Q71F23 Centromere protein U chr4 GO:0000776 Not Cancer Driver No 51 0.122 298 42 0.141 0
CENPV CENPV Q7Z7K6 Centromere protein V chr17 GO:0000776 Not Cancer Driver No 16 0.058 154 2 0.013 0
CENPW_ENST00000368328 CENPW Q5EE01 Centromere protein W chr6 GO:0000776 Not Cancer Driver No 9 0.102 5 1 0.2 0
CENPX_ENST00000392359 CENPX A8MT69 Centromere protein X chr17 GO:0000776 Not Cancer Driver No 4 0.049 0 0 0.0 0
CFDP1 CFDP1 Q9UEE9 Craniofacial development protein 1 chr16 GO:0000776 Not Cancer Driver No 21 0.07 273 18 0.066 0
CHAMP1 CHAMP1 Q96JM3 Chromosome alignment-maintaining phosphoprotein 1 chr13 GO:0000776 Not Cancer Driver No 85 0.105 624 65 0.104 0
CHMP1A CHMP1A Q9HD42 Charged multivesicular body protein 1a chr16 GO:0000776 Not Cancer Driver No 18 0.092 110 6 0.055 0
CHMP1B CHMP1B Q7LBR1 Charged multivesicular body protein 1b chr18 GO:0000776 Not Cancer Driver No 23 0.116 133 16 0.12 0
CHMP2A_ENST00000601220 CHMP2A O43633 Charged multivesicular body protein 2a chr19 GO:0000776 Not Cancer Driver No 29 0.131 161 22 0.137 0
CHMP2B CHMP2B Q9UQN3 Charged multivesicular body protein 2b chr3 GO:0000776 Not Cancer Driver No 28 0.131 183 25 0.137 4
CHMP3 CHMP3 Q9Y3E7 Charged multivesicular body protein 3 chr2 GO:0000776 Not Cancer Driver No 25 0.113 137 13 0.095 0
CHMP4A_ENST00000609024 CHMP4A Q9BY43 Charged multivesicular body protein 4a chr14 GO:0000776 Not Cancer Driver No 24 0.108 204 23 0.113 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 GO:0000776 Not Cancer Driver No 25 0.112 201 22 0.109 2
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 GO:0000776 Not Cancer Driver No 33 0.142 224 31 0.138 0
CHMP5 CHMP5 Q9NZZ3 Charged multivesicular body protein 5 chr9 GO:0000776 Not Cancer Driver No 24 0.11 195 18 0.092 0
CHMP6 CHMP6 Q96FZ7 Charged multivesicular body protein 6 chr17 GO:0000776 Not Cancer Driver No 26 0.129 88 16 0.182 0
CHMP7_ENST00000313219 CHMP7 Q8WUX9 Charged multivesicular body protein 7 chr8 GO:0000776 Not Cancer Driver No 50 0.11 140 15 0.107 0
CKAP5 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 GO:0000776 Not Cancer Driver No 198 0.097 634 64 0.101 0
CLASP1_ENST00000646274 CLASP1 Q7Z460 CLIP-associating protein 1 chr2 GO:0000776 Not Cancer Driver No 163 0.106 642 70 0.109 0
CLASP2 CLASP2 O75122 CLIP-associating protein 2 chr3 GO:0000776 Not Cancer Driver No 158 0.122 676 94 0.139 0
CLIP1 CLIP1 P30622 CAP-Gly domain-containing linker protein 1 chr12 GO:0000776 Census, Compendium Yes 184 0.128 1194 136 0.114 0
CSNK1A1_ENST00000377843 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 GO:0000776 Not Cancer Driver No 44 0.131 46 3 0.065 0
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 GO:0000776 Census Yes 172 0.135 817 111 0.136 11
DCTN2_ENST00000548249 DCTN2 Q13561 Dynactin subunit 2 chr12 GO:0000776 Not Cancer Driver No 46 0.115 253 32 0.126 0
DCTN3 DCTN3 O75935 Dynactin subunit 3 chr9 GO:0000776 Not Cancer Driver No 18 0.097 3 0 0.0 0
DCTN4_ENST00000447998 DCTN4 Q9UJW0 Dynactin subunit 4 chr5 GO:0000776 Not Cancer Driver No 47 0.102 138 18 0.13 0
DCTN5 DCTN5 Q9BTE1 Dynactin subunit 5 chr16 GO:0000776 Not Cancer Driver No 23 0.126 0 0 0.0 0
DCTN6 DCTN6 O00399 Dynactin subunit 6 chr8 GO:0000776 Not Cancer Driver No 25 0.132 45 0 0.0 0
DSN1 DSN1 Q9H410 Kinetochore-associated protein DSN1 homolog chr20 GO:0000776 Not Cancer Driver No 45 0.126 191 28 0.147 0
DYNC1I1 DYNC1I1 O14576 Cytoplasmic dynein 1 intermediate chain 1 chr7 GO:0000776 Not Cancer Driver No 146 0.226 255 60 0.235 0
DYNC1LI1 DYNC1LI1 Q9Y6G9 Cytoplasmic dynein 1 light intermediate chain 1 chr3 GO:0000776 Not Cancer Driver No 46 0.088 208 20 0.096 0
DYNC1LI2 DYNC1LI2 O43237 Cytoplasmic dynein 1 light intermediate chain 2 chr16 GO:0000776 Not Cancer Driver No 43 0.087 211 14 0.066 0
DYNLL1_ENST00000242577 DYNLL1 P63167 Dynein light chain 1, cytoplasmic chr12 GO:0000776 Not Cancer Driver No 9 0.101 0 0 0.0 0
DYNLT3 DYNLT3 P51808 Dynein light chain Tctex-type 3 chrX GO:0000776 Not Cancer Driver No 11 0.095 0 0 0.0 0
ERCC6L ERCC6L Q2NKX8 DNA excision repair protein ERCC-6-like chrX GO:0000776 Not Cancer Driver No 137 0.11 532 72 0.135 0
FBXO28 FBXO28 Q9NVF7 F-box only protein 28 chr1 GO:0000776 Not Cancer Driver No 49 0.133 230 30 0.13 0
FBXW11 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 GO:0000776 Not Cancer Driver No 75 0.138 20 3 0.15 7
GPATCH11 GPATCH11 Q8N954 G patch domain-containing protein 11 chr2 GO:0000776 Not Cancer Driver No 16 0.056 231 13 0.056 0
HJURP HJURP Q8NCD3 Holliday junction recognition protein chr2 GO:0000776 Not Cancer Driver No 108 0.144 572 85 0.149 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0000776 Not Cancer Driver No 77 0.093 504 45 0.089 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0000776 Not Cancer Driver No 59 0.112 335 37 0.11 0
INCENP INCENP Q9NQS7 Inner centromere protein chr11 GO:0000776 Not Cancer Driver No 107 0.117 856 103 0.12 0
ITGB3BP_ENST00000271002 ITGB3BP Q13352 Centromere protein R chr1 GO:0000776 Not Cancer Driver No 19 0.107 122 14 0.115 0
KANSL1_ENST00000262419 KANSL1 Q7Z3B3 KAT8 regulatory NSL complex subunit 1 chr17 GO:0000776 Not Cancer Driver No 168 0.152 876 130 0.148 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 GO:0000776 Not Cancer Driver No 107 0.129 266 27 0.102 0
KAT8_ENST00000219797 KAT8 Q9H7Z6 Histone acetyltransferase KAT8 chr16 GO:0000776 Not Cancer Driver No 66 0.144 156 20 0.128 4
KIF18A KIF18A Q8NI77 Kinesin-like protein KIF18A chr11 GO:0000776 Not Cancer Driver No 114 0.127 405 60 0.148 0
KIF22 KIF22 Q14807 Kinesin-like protein KIF22 chr16 GO:0000776 Not Cancer Driver No 79 0.119 322 35 0.109 4
KIF2B KIF2B Q8N4N8 Kinesin-like protein KIF2B chr17 GO:0000776 Not Cancer Driver No 314 0.467 189 116 0.614 0
KIF2C KIF2C Q99661 Kinesin-like protein KIF2C chr1 GO:0000776 Not Cancer Driver No 110 0.152 337 63 0.187 0
KNL1 KNL1 Q8NG31 Kinetochore scaffold 1 chr15 GO:0000776 Census Yes 272 0.116 1265 135 0.107 1
KNSTRN KNSTRN Q9Y448 Small kinetochore-associated protein chr15 GO:0000776 Census Yes 75 0.237 246 67 0.272 0
LRWD1 LRWD1 Q9UFC0 Leucine-rich repeat and WD repeat-containing protein 1 chr7 GO:0000776 Not Cancer Driver No 75 0.116 133 17 0.128 0
MAD1L1_ENST00000399654 MAD1L1 Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 chr7 GO:0000776 Not Cancer Driver No 117 0.163 526 77 0.146 0
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 GO:0000776 Not Cancer Driver No 26 0.127 12 1 0.083 0
MEAF6_ENST00000296214 MEAF6 Q9HAF1 Chromatin modification-related protein MEAF6 chr1 GO:0000776 Not Cancer Driver No 22 0.115 171 21 0.123 0
MEIKIN MEIKIN A0A087WXM9 Meiosis-specific kinetochore protein chr5 GO:0000776 Not Cancer Driver No 2 0.005 221 1 0.005 0
MIS12 MIS12 Q9H081 Protein MIS12 homolog chr17 GO:0000776 Not Cancer Driver No 14 0.068 15 2 0.133 0
MTBP MTBP Q96DY7 Mdm2-binding protein chr8 GO:0000776 Not Cancer Driver No 99 0.11 259 27 0.104 0
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 GO:0000776 Not Cancer Driver No 80 0.125 313 45 0.144 0
NDE1_ENST00000396354 NDE1 Q9NXR1 Nuclear distribution protein nudE homolog 1 chr16 GO:0000776 Not Cancer Driver No 45 0.134 316 42 0.133 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0000776 Not Cancer Driver No 32 0.093 202 16 0.079 0
NEK2 NEK2 P51955 Serine/threonine-protein kinase Nek2 chr1 GO:0000776 Not Cancer Driver No 61 0.137 92 19 0.207 0
NSL1 NSL1 Q96IY1 Kinetochore-associated protein NSL1 homolog chr1 GO:0000776 Not Cancer Driver No 30 0.107 117 12 0.103 0
NUDCD2 NUDCD2 Q8WVJ2 NudC domain-containing protein 2 chr5 GO:0000776 Not Cancer Driver No 12 0.076 39 6 0.154 0
NUF2_ENST00000367900 NUF2 Q9BZD4 Kinetochore protein Nuf2 chr1 GO:0000776 Not Cancer Driver No 97 0.209 74 20 0.27 0
NUP107 NUP107 P57740 Nuclear pore complex protein Nup107 chr12 GO:0000776 Not Cancer Driver No 127 0.137 183 26 0.142 5
NUP133 NUP133 Q8WUM0 Nuclear pore complex protein Nup133 chr1 GO:0000776 Not Cancer Driver No 143 0.124 116 16 0.138 3
NUP160 NUP160 Q12769 Nuclear pore complex protein Nup160 chr11 GO:0000776 Not Cancer Driver No 138 0.096 48 1 0.021 0
NUP37_ENST00000251074 NUP37 Q8NFH4 Nucleoporin Nup37 chr12 GO:0000776 Not Cancer Driver No 39 0.12 0 0 0.0 0
NUP43 NUP43 Q8NFH3 Nucleoporin Nup43 chr6 GO:0000776 Not Cancer Driver No 47 0.124 103 9 0.087 0
NUP85 NUP85 Q9BW27 Nuclear pore complex protein Nup85 chr17 GO:0000776 Not Cancer Driver No 68 0.104 32 4 0.125 2
NUP98_ENST00000359171 NUP98 P52948 Nuclear pore complex protein Nup98-Nup96 chr11 GO:0000776 Census Yes 227 0.125 1008 107 0.106 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0000776 Not Cancer Driver No 42 0.102 82 11 0.134 7
PHF2 PHF2 O75151 Lysine-specific demethylase PHF2 chr9 GO:0000776 Not Cancer Driver No 131 0.12 725 80 0.11 0
PHF6_ENST00000370803 PHF6 Q8IWS0 PHD finger protein 6 chrX GO:0000776 Census, Compendium Yes 52 0.142 172 19 0.11 6
PINX1 PINX1 Q96BK5 PIN2/TERF1-interacting telomerase inhibitor 1 chr8 GO:0000776 Not Cancer Driver No 66 0.201 328 66 0.201 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0000776 Not Cancer Driver No 87 0.144 119 13 0.109 0
PMF1_ENST00000368277 PMF1 Q6P1K2 Polyamine-modulated factor 1 chr1 GO:0000776 Not Cancer Driver No 20 0.098 76 6 0.079 0
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 GO:0000776 Not Cancer Driver No 26 0.08 23 4 0.174 0
PPP1R12A_ENST00000261207 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 GO:0000776 Not Cancer Driver No 107 0.104 821 89 0.108 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0000776 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSEN2 PSEN2 P49810 Presenilin-2 chr1 GO:0000776 Not Cancer Driver No 68 0.152 89 16 0.18 7
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0000776 Not Cancer Driver No 65 0.111 159 17 0.107 0
RASSF2 RASSF2 P50749 Ras association domain-containing protein 2 chr20 GO:0000776 Not Cancer Driver No 90 0.276 126 44 0.349 0
REC8_ENST00000611366 REC8 O95072 Meiotic recombination protein REC8 homolog chr14 GO:0000776 Not Cancer Driver No 60 0.11 244 26 0.107 0
SEC13_ENST00000350697 SEC13 P55735 Protein SEC13 homolog chr3 GO:0000776 Not Cancer Driver No 34 0.106 36 6 0.167 0
SEH1L_ENST00000262124 SEH1L Q96EE3 Nucleoporin SEH1 chr18 GO:0000776 Not Cancer Driver No 40 0.111 71 11 0.155 0
SEPT2_ENST00000360051 SEPTIN2 Q15019 Septin-2 chr2 GO:0000776 Not Cancer Driver No 49 0.136 101 11 0.109 0
SEPT6 SEPTIN6 Q14141 Septin-6 chrX GO:0000776 Not Cancer Driver No 69 0.159 161 25 0.155 0
SEPT7_ENST00000350320 SEPTIN7 Q16181 Septin-7 chr7 GO:0000776 Not Cancer Driver No 49 0.112 200 21 0.105 0
SGO1 SGO1 Q5FBB7 Shugoshin 1 chr3 GO:0000776 Not Cancer Driver No 57 0.102 360 39 0.108 1
SGO2 SGO2 Q562F6 Shugoshin 2 chr2 GO:0000776 Not Cancer Driver No 164 0.13 1025 134 0.131 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0000776 Compendium Yes 172 0.135 617 73 0.118 0
SKA1_ENST00000398452 SKA1 Q96BD8 Spindle and kinetochore-associated protein 1 chr18 GO:0000776 Not Cancer Driver No 23 0.09 74 7 0.095 0
SKA2 SKA2 Q8WVK7 Spindle and kinetochore-associated protein 2 chr17 GO:0000776 Not Cancer Driver No 12 0.099 44 6 0.136 0
SKA3 SKA3 Q8IX90 Spindle and kinetochore-associated protein 3 chr13 GO:0000776 Not Cancer Driver No 56 0.136 230 32 0.139 0
SMC1A SMC1A Q14683 Structural maintenance of chromosomes protein 1A chrX GO:0000776 Census, Compendium Yes 200 0.162 717 114 0.159 21
SPAG5 SPAG5 Q96R06 Sperm-associated antigen 5 chr17 GO:0000776 Not Cancer Driver No 136 0.114 636 83 0.131 0
SPC24 SPC24 Q8NBT2 Kinetochore protein Spc24 chr19 GO:0000776 Not Cancer Driver No 9 0.046 88 5 0.057 0
SPC25 SPC25 Q9HBM1 Kinetochore protein Spc25 chr2 GO:0000776 Not Cancer Driver No 15 0.067 34 2 0.059 0
SPOUT1 SPOUT1 Q5T280 Putative methyltransferase C9orf114 chr9 GO:0000776 Not Cancer Driver No 35 0.093 166 18 0.108 0
SS18L1 SS18L1 O75177 Calcium-responsive transactivator chr20 GO:0000776 Census Yes 53 0.134 356 48 0.135 0
SUGT1 SUGT1 Q9Y2Z0 Protein SGT1 homolog chr13 GO:0000776 Not Cancer Driver No 31 0.085 119 5 0.042 0
SUMO3_ENST00000332859 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 GO:0000776 Not Cancer Driver No 7 0.068 87 5 0.057 0
TEX14 TEX14 Q8IWB6 Inactive serine/threonine-protein kinase TEX14 chr17 GO:0000776 Not Cancer Driver No 214 0.143 872 115 0.132 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 GO:0000776 Not Cancer Driver No 227 0.115 1632 190 0.116 0
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0000776 Census Yes 311 0.132 1990 266 0.134 0
TRAPPC12 TRAPPC12 Q8WVT3 Trafficking protein particle complex subunit 12 chr2 GO:0000776 Not Cancer Driver No 88 0.12 318 31 0.097 0
TTK TTK P33981 Dual specificity protein kinase TTK chr6 GO:0000776 Not Cancer Driver No 136 0.159 352 46 0.131 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 GO:0000776 Census, Compendium Yes 140 0.131 33 9 0.273 0
ZNF207_ENST00000321233 ZNF207 O43670 BUB3-interacting and GLEBS motif-containing protein ZNF207 chr17 GO:0000776 Not Cancer Driver No 68 0.142 426 58 0.136 0
ZNF276 ZNF276 Q8N554 Zinc finger protein 276 chr16 GO:0000776 Not Cancer Driver No 74 0.121 349 34 0.097 0
ZW10 ZW10 O43264 Centromere/kinetochore protein zw10 homolog chr11 GO:0000776 Not Cancer Driver No 90 0.116 63 11 0.175 0
ZWILCH ZWILCH Q9H900 Protein zwilch homolog chr15 GO:0000776 Not Cancer Driver No 67 0.113 42 5 0.119 0
ZWINT ZWINT O95229 ZW10 interactor chr10 GO:0000776 Not Cancer Driver No 65 0.235 168 44 0.262 0