Total number of protein in "GO:0000075" GO term: 42
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0000075 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | GO:0000075 | Not Cancer Driver | No | 51 | 0.148 | 63 | 8 | 0.127 | 0 |
| CASP2 | CASP2 | P42575 | Caspase-2 | chr7 | GO:0000075 | Not Cancer Driver | No | 63 | 0.139 | 42 | 12 | 0.286 | 0 |
| CCND1 | CCND1 | P24385 | G1/S-specific cyclin-D1 | chr11 | GO:0000075 | Census, Compendium | Yes | 55 | 0.186 | 31 | 25 | 0.806 | 0 |
| CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | GO:0000075 | Not Cancer Driver | No | 24 | 0.081 | 0 | 0 | 0.0 | 0 |
| CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0000075 | Census, Compendium | Yes | 48 | 0.293 | 121 | 30 | 0.248 | 0 |
| CDKN1B | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0000075 | Census, Compendium | Yes | 19 | 0.096 | 198 | 19 | 0.096 | 0 |
| CHEK2_ENST00000405598 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | GO:0000075 | Census, Compendium | Yes | 335 | 0.617 | 157 | 130 | 0.828 | 13 |
| CHFR | CHFR | Q96EP1 | E3 ubiquitin-protein ligase CHFR | chr12 | GO:0000075 | Not Cancer Driver | No | 85 | 0.128 | 341 | 54 | 0.158 | 0 |
| CHMP4C | CHMP4C | Q96CF2 | Charged multivesicular body protein 4c | chr8 | GO:0000075 | Not Cancer Driver | No | 33 | 0.142 | 224 | 31 | 0.138 | 0 |
| CRADD_ENST00000332896 | CRADD | P78560 | Death domain-containing protein CRADD | chr12 | GO:0000075 | Not Cancer Driver | No | 35 | 0.176 | 45 | 5 | 0.111 | 1 |
| FBXO31 | FBXO31 | Q5XUX0 | F-box only protein 31 | chr16 | GO:0000075 | Not Cancer Driver | No | 72 | 0.134 | 231 | 30 | 0.13 | 0 |
| GIGYF2_ENST00000409547 | GIGYF2 | Q6Y7W6 | GRB10-interacting GYF protein 2 | chr2 | GO:0000075 | Not Cancer Driver | No | 176 | 0.135 | 1096 | 158 | 0.144 | 6 |
| GML | GML | Q99445 | Glycosyl-phosphatidylinositol-anchored molecule-like protein | chr8 | GO:0000075 | Not Cancer Driver | No | 49 | 0.31 | 12 | 6 | 0.5 | 0 |
| GTSE1 | GTSE1 | Q9NYZ3 | G2 and S phase-expressed protein 1 | chr22 | GO:0000075 | Not Cancer Driver | No | 91 | 0.126 | 660 | 85 | 0.129 | 0 |
| HORMAD1 | HORMAD1 | Q86X24 | HORMA domain-containing protein 1 | chr1 | GO:0000075 | Not Cancer Driver | No | 76 | 0.193 | 178 | 31 | 0.174 | 0 |
| HUS1 | HUS1 | O60921 | Checkpoint protein HUS1 | chr7 | GO:0000075 | Not Cancer Driver | No | 25 | 0.089 | 17 | 2 | 0.118 | 0 |
| HUS1B | HUS1B | Q8NHY5 | Checkpoint protein HUS1B | chr6 | GO:0000075 | Not Cancer Driver | No | 50 | 0.18 | 10 | 1 | 0.1 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0000075 | Census, Compendium | Yes | 56 | 0.114 | 297 | 37 | 0.125 | 0 |
| MUC1_ENST00000611571 | MUC1 | P15941 | Mucin-1 | chr1 | GO:0000075 | Census | Yes | 40 | 0.032 | 1050 | 19 | 0.018 | 0 |
| NSUN2 | NSUN2 | Q08J23 | RNA cytosine C(5)-methyltransferase NSUN2 | chr5 | GO:0000075 | Not Cancer Driver | No | 112 | 0.146 | 221 | 21 | 0.095 | 1 |
| PIDD1 | PIDD1 | Q9HB75 | p53-induced death domain-containing protein 1 | chr11 | GO:0000075 | Not Cancer Driver | No | 93 | 0.102 | 137 | 14 | 0.102 | 0 |
| PLK2 | PLK2 | Q9NYY3 | Serine/threonine-protein kinase PLK2 | chr5 | GO:0000075 | Not Cancer Driver | No | 92 | 0.134 | 178 | 21 | 0.118 | 0 |
| PLK3 | PLK3 | Q9H4B4 | Serine/threonine-protein kinase PLK3 | chr1 | GO:0000075 | Not Cancer Driver | No | 75 | 0.116 | 202 | 15 | 0.074 | 0 |
| PLK5 | PLK5 | Q496M5 | Inactive serine/threonine-protein kinase PLK5 | chr19 | GO:0000075 | Not Cancer Driver | No | 8 | 0.024 | 215 | 4 | 0.019 | 0 |
| PML | PML | P29590 | Protein PML | chr15 | GO:0000075 | Census, Compendium | Yes | 112 | 0.127 | 312 | 34 | 0.109 | 0 |
| PRAP1 | PRAP1 | Q96NZ9 | Proline-rich acidic protein 1 | chr10 | GO:0000075 | Not Cancer Driver | No | 14 | 0.093 | 124 | 13 | 0.105 | 0 |
| PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0000075 | Not Cancer Driver | No | 538 | 0.13 | 421 | 61 | 0.145 | 2 |
| RAD1 | RAD1 | O60671 | Cell cycle checkpoint protein RAD1 | chr5 | GO:0000075 | Not Cancer Driver | No | 29 | 0.103 | 4 | 1 | 0.25 | 0 |
| RFWD3 | RFWD3 | Q6PCD5 | E3 ubiquitin-protein ligase RFWD3 | chr16 | GO:0000075 | Census | Yes | 68 | 0.088 | 318 | 30 | 0.094 | 1 |
| RPA2_ENST00000373912 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | GO:0000075 | Not Cancer Driver | No | 28 | 0.104 | 114 | 16 | 0.14 | 0 |
| RPL26 | RPL26 | P61254 | 60S ribosomal protein L26 | chr17 | GO:0000075 | Not Cancer Driver | No | 16 | 0.11 | 114 | 13 | 0.114 | 0 |
| RPS27L | RPS27L | Q71UM5 | 40S ribosomal protein S27-like | chr15 | GO:0000075 | Not Cancer Driver | No | 4 | 0.048 | 22 | 2 | 0.091 | 0 |
| SDE2 | SDE2 | Q6IQ49 | Replication stress response regulator SDE2 | chr1 | GO:0000075 | Not Cancer Driver | No | 56 | 0.124 | 290 | 35 | 0.121 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0000075 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TREX1_ENST00000625293 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0000075 | Not Cancer Driver | No | 26 | 0.083 | 98 | 10 | 0.102 | 18 |
| TRIAP1 | TRIAP1 | O43715 | TP53-regulated inhibitor of apoptosis 1 | chr12 | GO:0000075 | Not Cancer Driver | No | 9 | 0.118 | 20 | 1 | 0.05 | 0 |
| TRIP13 | TRIP13 | Q15645 | Pachytene checkpoint protein 2 homolog | chr5 | GO:0000075 | Not Cancer Driver | No | 62 | 0.144 | 30 | 6 | 0.2 | 1 |
| TTK | TTK | P33981 | Dual specificity protein kinase TTK | chr6 | GO:0000075 | Not Cancer Driver | No | 136 | 0.159 | 352 | 46 | 0.131 | 0 |
| VPS4A | VPS4A | Q9UN37 | Vacuolar protein sorting-associated protein 4A | chr16 | GO:0000075 | Not Cancer Driver | No | 48 | 0.11 | 167 | 17 | 0.102 | 4 |
| WAC | WAC | Q9BTA9 | WW domain-containing adapter protein with coiled-coil | chr10 | GO:0000075 | Not Cancer Driver | No | 106 | 0.164 | 571 | 95 | 0.166 | 0 |
| ZFYVE19 | ZFYVE19 | Q96K21 | Abscission/NoCut checkpoint regulator | chr15 | GO:0000075 | Not Cancer Driver | No | 41 | 0.087 | 361 | 28 | 0.078 | 0 |