Total number of protein in "GO:2001259" GO term: 68
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCC8_ENST00000389817 | ABCC8 | Q09428 | ATP-binding cassette sub-family C member 8 | chr11 | GO:2001259 | Not Cancer Driver | No | 255 | 0.161 | 138 | 23 | 0.167 | 97 |
| ACTN2_ENST00000366578 | ACTN2 | P35609 | Alpha-actinin-2 | chr1 | GO:2001259 | Not Cancer Driver | No | 227 | 0.254 | 131 | 29 | 0.221 | 9 |
| ADRB2 | ADRB2 | P07550 | Beta-2 adrenergic receptor | chr5 | GO:2001259 | Not Cancer Driver | No | 52 | 0.126 | 35 | 4 | 0.114 | 0 |
| AKAP6 | AKAP6 | Q13023 | A-kinase anchor protein 6 | chr14 | GO:2001259 | Not Cancer Driver | No | 383 | 0.165 | 1456 | 240 | 0.165 | 0 |
| ALG10B | ALG10B | Q5I7T1 | Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase | chr12 | GO:2001259 | Not Cancer Driver | No | 90 | 0.19 | 0 | 0 | 0.0 | 0 |
| AMIGO1_ENST00000369862 | AMIGO1 | Q86WK6 | Amphoterin-induced protein 1 | chr1 | GO:2001259 | Not Cancer Driver | No | 46 | 0.093 | 85 | 7 | 0.082 | 0 |
| ANK2 | ANK2 | Q01484 | Ankyrin-2 | chr4 | GO:2001259 | Not Cancer Driver | No | 770 | 0.195 | 2844 | 566 | 0.199 | 4 |
| ANK3 | ANK3 | Q12955 | Ankyrin-3 | chr10 | GO:2001259 | Not Cancer Driver | No | 860 | 0.196 | 3054 | 579 | 0.19 | 0 |
| ARC | ARC | Q7LC44 | Activity-regulated cytoskeleton-associated protein | chr8 | GO:2001259 | Not Cancer Driver | No | 64 | 0.162 | 194 | 29 | 0.149 | 0 |
| CACNA2D1_ENST00000356253 | CACNA2D1 | P54289 | Voltage-dependent calcium channel subunit alpha-2/delta-1 | chr7 | GO:2001259 | Not Cancer Driver | No | 277 | 0.251 | 99 | 25 | 0.253 | 0 |
| CACNB2 | CACNB2 | Q08289 | Voltage-dependent L-type calcium channel subunit beta-2 | chr10 | GO:2001259 | Not Cancer Driver | No | 155 | 0.235 | 478 | 106 | 0.222 | 0 |
| CACNB3 | CACNB3 | P54284 | Voltage-dependent L-type calcium channel subunit beta-3 | chr12 | GO:2001259 | Not Cancer Driver | No | 58 | 0.12 | 258 | 30 | 0.116 | 0 |
| CACNG2 | CACNG2 | Q9Y698 | Voltage-dependent calcium channel gamma-2 subunit | chr22 | GO:2001259 | Not Cancer Driver | No | 57 | 0.176 | 90 | 16 | 0.178 | 1 |
| CACNG3 | CACNG3 | O60359 | Voltage-dependent calcium channel gamma-3 subunit | chr16 | GO:2001259 | Not Cancer Driver | No | 126 | 0.4 | 69 | 37 | 0.536 | 0 |
| CACNG4 | CACNG4 | Q9UBN1 | Voltage-dependent calcium channel gamma-4 subunit | chr17 | GO:2001259 | Not Cancer Driver | No | 51 | 0.156 | 71 | 17 | 0.239 | 0 |
| CALM1 | CALM1 | P0DP23 | Calmodulin-1 | chr14 | GO:2001259 | Not Cancer Driver | No | 19 | 0.128 | 115 | 15 | 0.13 | 7 |
| CALM2 | CALM2 | P0DP24 | Calmodulin-2 | chr2 | GO:2001259 | Not Cancer Driver | No | 18 | 0.121 | 115 | 13 | 0.113 | 8 |
| CALM3_ENST00000596362 | CALM3 | P0DP25 | Calmodulin-3 | chr19 | GO:2001259 | Not Cancer Driver | No | 17 | 0.114 | 115 | 10 | 0.087 | 3 |
| CASQ1 | CASQ1 | P31415 | Calsequestrin-1 | chr1 | GO:2001259 | Not Cancer Driver | No | 77 | 0.194 | 110 | 18 | 0.164 | 4 |
| CCL2 | CCL2 | P13500 | C-C motif chemokine 2 | chr17 | GO:2001259 | Not Cancer Driver | No | 20 | 0.202 | 15 | 5 | 0.333 | 0 |
| CCR2_ENST00000400888 | CCR2 | P41597 | C-C chemokine receptor type 2 | chr3 | GO:2001259 | Not Cancer Driver | No | 81 | 0.217 | 23 | 1 | 0.043 | 0 |
| CDK5 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:2001259 | Not Cancer Driver | No | 48 | 0.164 | 5 | 1 | 0.2 | 0 |
| CRACR2A | CRACR2A | Q9BSW2 | EF-hand calcium-binding domain-containing protein 4B | chr12 | GO:2001259 | Not Cancer Driver | No | 88 | 0.12 | 436 | 60 | 0.138 | 0 |
| CTSS | CTSS | P25774 | Cathepsin S | chr1 | GO:2001259 | Not Cancer Driver | No | 54 | 0.163 | 0 | 0 | 0.0 | 0 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:2001259 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| EDNRA | EDNRA | P25101 | Endothelin-1 receptor | chr4 | GO:2001259 | Not Cancer Driver | No | 62 | 0.145 | 21 | 6 | 0.286 | 2 |
| EHD3 | EHD3 | Q9NZN3 | EH domain-containing protein 3 | chr2 | GO:2001259 | Not Cancer Driver | No | 104 | 0.194 | 77 | 18 | 0.234 | 0 |
| EPHB2 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:2001259 | Not Cancer Driver | No | 186 | 0.176 | 119 | 17 | 0.143 | 7 |
| FAM173A | ANTKMT | Q9BQD7 | Adenine nucleotide translocase lysine N-methyltransferase | chr16 | GO:2001259 | Not Cancer Driver | No | 10 | 0.043 | 37 | 3 | 0.081 | 0 |
| FAM173B | ATPSCKMT | Q6P4H8 | ATP synthase subunit C lysine N-methyltransferase | chr5 | GO:2001259 | Not Cancer Driver | No | 41 | 0.176 | 10 | 1 | 0.1 | 0 |
| GAL | GAL | P22466 | Galanin peptides | chr11 | GO:2001259 | Not Cancer Driver | No | 17 | 0.138 | 36 | 2 | 0.056 | 1 |
| GALR2 | GALR2 | O43603 | Galanin receptor type 2 | chr17 | GO:2001259 | Not Cancer Driver | No | 40 | 0.103 | 0 | 0 | 0.0 | 0 |
| GSTM2 | GSTM2 | P28161 | Glutathione S-transferase Mu 2 | chr1 | GO:2001259 | Not Cancer Driver | No | 26 | 0.119 | 5 | 0 | 0.0 | 0 |
| GSTO1 | GSTO1 | P78417 | Glutathione S-transferase omega-1 | chr10 | GO:2001259 | Not Cancer Driver | No | 26 | 0.108 | 18 | 1 | 0.056 | 0 |
| HAP1_ENST00000310778 | HAP1 | P54257 | Huntingtin-associated protein 1 | chr17 | GO:2001259 | Not Cancer Driver | No | 97 | 0.145 | 454 | 60 | 0.132 | 0 |
| HTT | HTT | P42858 | Huntingtin | chr4 | GO:2001259 | Not Cancer Driver | No | 336 | 0.107 | 666 | 69 | 0.104 | 2 |
| IFNG | IFNG | P01579 | Interferon gamma | chr12 | GO:2001259 | Not Cancer Driver | No | 51 | 0.307 | 23 | 6 | 0.261 | 0 |
| IFNGR2_ENST00000290219 | IFNGR2 | P38484 | Interferon gamma receptor 2 | chr21 | GO:2001259 | Not Cancer Driver | No | 36 | 0.107 | 18 | 2 | 0.111 | 5 |
| JPH2 | JPH2 | Q9BR39 | Junctophilin-2 | chr20 | GO:2001259 | Not Cancer Driver | No | 137 | 0.197 | 542 | 97 | 0.179 | 4 |
| KCNA1 | KCNA1 | Q09470 | Potassium voltage-gated channel subfamily A member 1 | chr12 | GO:2001259 | Not Cancer Driver | No | 176 | 0.356 | 69 | 34 | 0.493 | 17 |
| KCNC1_ENST00000379472 | KCNC1 | P48547 | Potassium voltage-gated channel subfamily C member 1 | chr11 | GO:2001259 | Not Cancer Driver | No | 91 | 0.178 | 110 | 18 | 0.164 | 1 |
| KCNC2 | KCNC2 | Q96PR1 | Potassium voltage-gated channel subfamily C member 2 | chr12 | GO:2001259 | Not Cancer Driver | No | 161 | 0.252 | 255 | 63 | 0.247 | 0 |
| KCNE2 | KCNE2 | Q9Y6J6 | Potassium voltage-gated channel subfamily E member 2 | chr21 | GO:2001259 | Not Cancer Driver | No | 25 | 0.203 | 2 | 0 | 0.0 | 5 |
| KCNIP2_ENST00000356640 | KCNIP2 | Q9NS61 | Kv channel-interacting protein 2 | chr10 | GO:2001259 | Not Cancer Driver | No | 34 | 0.126 | 89 | 16 | 0.18 | 0 |
| LRRC26 | LRRC26 | Q2I0M4 | Leucine-rich repeat-containing protein 26 | chr9 | GO:2001259 | Not Cancer Driver | No | 3 | 0.009 | 41 | 2 | 0.049 | 0 |
| LRRC38 | LRRC38 | Q5VT99 | Leucine-rich repeat-containing protein 38 | chr1 | GO:2001259 | Not Cancer Driver | No | 24 | 0.082 | 12 | 2 | 0.167 | 0 |
| LRRC52 | LRRC52 | Q8N7C0 | Leucine-rich repeat-containing protein 52 | chr1 | GO:2001259 | Not Cancer Driver | No | 61 | 0.195 | 15 | 4 | 0.267 | 0 |
| NIPSNAP2 | NIPSNAP2 | O75323 | Protein NipSnap homolog 2 | chr7 | GO:2001259 | Not Cancer Driver | No | 30 | 0.105 | 6 | 1 | 0.167 | 0 |
| NLGN3 | NLGN3 | Q9NZ94 | Neuroligin-3 | chrX | GO:2001259 | Not Cancer Driver | No | 158 | 0.186 | 257 | 54 | 0.21 | 2 |
| NOS1AP | NOS1AP | O75052 | Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein | chr1 | GO:2001259 | Not Cancer Driver | No | 94 | 0.186 | 255 | 53 | 0.208 | 1 |
| NPPA | NPPA | P01160 | Natriuretic peptides A | chr1 | GO:2001259 | Not Cancer Driver | No | 32 | 0.212 | 71 | 14 | 0.197 | 1 |
| NTSR1 | NTSR1 | P30989 | Neurotensin receptor type 1 | chr20 | GO:2001259 | Not Cancer Driver | No | 85 | 0.203 | 23 | 1 | 0.043 | 0 |
| P2RY6_ENST00000540342 | P2RY6 | Q15077 | P2Y purinoceptor 6 | chr11 | GO:2001259 | Not Cancer Driver | No | 50 | 0.152 | 10 | 5 | 0.5 | 0 |
| PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:2001259 | Not Cancer Driver | No | 57 | 0.098 | 99 | 13 | 0.131 | 23 |
| PIRT | PIRT | P0C851 | Phosphoinositide-interacting protein | chr17 | GO:2001259 | Not Cancer Driver | No | 24 | 0.175 | 3 | 1 | 0.333 | 0 |
| PKD2 | PKD2 | Q13563 | Polycystin-2 | chr4 | GO:2001259 | Not Cancer Driver | No | 113 | 0.117 | 375 | 35 | 0.093 | 10 |
| PLCG2 | PLCG2 | P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | chr16 | GO:2001259 | Not Cancer Driver | No | 248 | 0.196 | 142 | 30 | 0.211 | 1 |
| RELN | RELN | P78509 | Reelin | chr7 | GO:2001259 | Not Cancer Driver | No | 761 | 0.22 | 107 | 19 | 0.178 | 7 |
| RNF207 | RNF207 | Q6ZRF8 | RING finger protein 207 | chr1 | GO:2001259 | Not Cancer Driver | No | 48 | 0.076 | 198 | 13 | 0.066 | 0 |
| STAC | STAC | Q99469 | SH3 and cysteine-rich domain-containing protein | chr3 | GO:2001259 | Not Cancer Driver | No | 107 | 0.266 | 196 | 55 | 0.281 | 0 |
| STAC2 | STAC2 | Q6ZMT1 | SH3 and cysteine-rich domain-containing protein 2 | chr17 | GO:2001259 | Not Cancer Driver | No | 56 | 0.136 | 228 | 36 | 0.158 | 0 |
| STAC3 | STAC3 | Q96MF2 | SH3 and cysteine-rich domain-containing protein 3 | chr12 | GO:2001259 | Not Cancer Driver | No | 50 | 0.137 | 192 | 30 | 0.156 | 1 |
| STIM1_ENST00000300737 | STIM1 | Q13586 | Stromal interaction molecule 1 | chr11 | GO:2001259 | Not Cancer Driver | No | 70 | 0.102 | 387 | 45 | 0.116 | 13 |
| STIM2_ENST00000467087 | STIM2 | Q9P246 | Stromal interaction molecule 2 | chr4 | GO:2001259 | Not Cancer Driver | No | 82 | 0.11 | 387 | 45 | 0.116 | 0 |
| STIMATE | STIMATE | Q86TL2 | Store-operated calcium entry regulator STIMATE | chr3 | GO:2001259 | Not Cancer Driver | No | 27 | 0.092 | 61 | 4 | 0.066 | 0 |
| TMSB4X_ENST00000380633 | TMSB4X | P62328 | Thymosin beta-4 | chrX | GO:2001259 | Census | Yes | 7 | 0.159 | 44 | 7 | 0.159 | 0 |
| TRDN | TRDN | Q13061 | Triadin | chr6 | GO:2001259 | Not Cancer Driver | No | 129 | 0.177 | 639 | 102 | 0.16 | 1 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:2001259 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |