Total number of protein in "GO:2001243" GO term: 99
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACKR3 | ACKR3 | P25106 | Atypical chemokine receptor 3 | chr2 | GO:2001243 | Census, Compendium | Yes | 78 | 0.215 | 0 | 0 | 0.0 | 1 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:2001243 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| ARHGEF2 | ARHGEF2 | Q92974 | Rho guanine nucleotide exchange factor 2 | chr1 | GO:2001243 | Not Cancer Driver | No | 146 | 0.148 | 450 | 70 | 0.156 | 0 |
| ARMC10 | ARMC10 | Q8N2F6 | Armadillo repeat-containing protein 10 | chr7 | GO:2001243 | Not Cancer Driver | No | 39 | 0.114 | 58 | 4 | 0.069 | 0 |
| ATAD5 | ATAD5 | Q96QE3 | ATPase family AAA domain-containing protein 5 | chr17 | GO:2001243 | Not Cancer Driver | No | 200 | 0.108 | 1075 | 112 | 0.104 | 0 |
| BAG5_ENST00000299204 | BAG5 | Q9UL15 | BAG family molecular chaperone regulator 5 | chr14 | GO:2001243 | Not Cancer Driver | No | 37 | 0.083 | 63 | 7 | 0.111 | 0 |
| BCL2L1 | BCL2L1 | Q07817 | Bcl-2-like protein 1 | chr20 | GO:2001243 | Not Cancer Driver | No | 29 | 0.124 | 55 | 3 | 0.055 | 0 |
| BCL2L10_ENST00000260442 | BCL2L10 | Q9HD36 | Bcl-2-like protein 10 | chr15 | GO:2001243 | Not Cancer Driver | No | 10 | 0.049 | 34 | 1 | 0.029 | 0 |
| BCL2L2 | BCL2L2 | Q92843 | Bcl-2-like protein 2 | chr14 | GO:2001243 | Not Cancer Driver | No | 22 | 0.114 | 34 | 6 | 0.176 | 0 |
| BCL2_ENST00000333681 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:2001243 | Census, Compendium | Yes | 24 | 0.1 | 72 | 5 | 0.069 | 0 |
| BDKRB2 | BDKRB2 | P30411 | B2 bradykinin receptor | chr14 | GO:2001243 | Not Cancer Driver | No | 81 | 0.207 | 0 | 0 | 0.0 | 0 |
| BID_ENST00000551952 | BID | P55957 | BH3-interacting domain death agonist | chr22 | GO:2001243 | Not Cancer Driver | No | 23 | 0.118 | 74 | 9 | 0.122 | 0 |
| CCAR2 | CCAR2 | Q8N163 | Cell cycle and apoptosis regulator protein 2 | chr8 | GO:2001243 | Not Cancer Driver | No | 102 | 0.111 | 528 | 62 | 0.117 | 0 |
| CD44 | CD44 | P16070 | CD44 antigen | chr11 | GO:2001243 | Not Cancer Driver | No | 75 | 0.101 | 542 | 60 | 0.111 | 0 |
| CD74 | CD74 | P04233 | HLA class II histocompatibility antigen gamma chain | chr5 | GO:2001243 | Census | Yes | 31 | 0.105 | 185 | 20 | 0.108 | 0 |
| CDKN2D_ENST00000335766 | CDKN2D | P55273 | Cyclin-dependent kinase 4 inhibitor D | chr19 | GO:2001243 | Not Cancer Driver | No | 17 | 0.102 | 44 | 3 | 0.068 | 0 |
| CLU_ENST00000523500 | CLU | P10909 | Clusterin | chr8 | GO:2001243 | Not Cancer Driver | No | 69 | 0.154 | 156 | 27 | 0.173 | 0 |
| CREB3 | CREB3 | O43889 | Cyclic AMP-responsive element-binding protein 3 | chr9 | GO:2001243 | Not Cancer Driver | No | 33 | 0.089 | 168 | 11 | 0.065 | 0 |
| CREB3L1 | CREB3L1 | Q96BA8 | Cyclic AMP-responsive element-binding protein 3-like protein 1 | chr11 | GO:2001243 | Census | Yes | 68 | 0.131 | 372 | 50 | 0.134 | 0 |
| CXCL12_ENST00000374429 | CXCL12 | P48061 | Stromal cell-derived factor 1 | chr10 | GO:2001243 | Not Cancer Driver | No | 16 | 0.172 | 0 | 0 | 0.0 | 0 |
| DDIAS | DDIAS | Q8IXT1 | DNA damage-induced apoptosis suppressor protein | chr11 | GO:2001243 | Not Cancer Driver | No | 125 | 0.125 | 370 | 59 | 0.159 | 0 |
| DDX3X_ENST00000629496 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:2001243 | Census, Compendium | Yes | 133 | 0.201 | 301 | 47 | 0.156 | 18 |
| DNAJA1 | DNAJA1 | P31689 | DnaJ homolog subfamily A member 1 | chr9 | GO:2001243 | Not Cancer Driver | No | 37 | 0.093 | 153 | 16 | 0.105 | 0 |
| ELL3 | ELL3 | Q9HB65 | RNA polymerase II elongation factor ELL3 | chr15 | GO:2001243 | Not Cancer Driver | No | 50 | 0.126 | 186 | 13 | 0.07 | 0 |
| ENO1 | ENO1 | P06733 | Alpha-enolase | chr1 | GO:2001243 | Not Cancer Driver | No | 51 | 0.118 | 21 | 2 | 0.095 | 0 |
| EPO | EPO | P01588 | Erythropoietin | chr7 | GO:2001243 | Not Cancer Driver | No | 27 | 0.14 | 9 | 1 | 0.111 | 1 |
| FIGNL1 | FIGNL1 | Q6PIW4 | Fidgetin-like protein 1 | chr7 | GO:2001243 | Not Cancer Driver | No | 75 | 0.111 | 224 | 23 | 0.103 | 0 |
| GPX1_ENST00000620890 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:2001243 | Not Cancer Driver | No | 38 | 0.187 | 12 | 1 | 0.083 | 0 |
| GRINA_ENST00000395068 | GRINA | Q7Z429 | Protein lifeguard 1 | chr8 | GO:2001243 | Not Cancer Driver | No | 39 | 0.105 | 150 | 15 | 0.1 | 0 |
| HDAC1 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | GO:2001243 | Not Cancer Driver | No | 47 | 0.098 | 135 | 10 | 0.074 | 0 |
| HELLS_ENST00000348459 | HELLS | Q9NRZ9 | Lymphoid-specific helicase | chr10 | GO:2001243 | Not Cancer Driver | No | 78 | 0.093 | 227 | 25 | 0.11 | 0 |
| HERPUD1 | HERPUD1 | Q15011 | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein | chr16 | GO:2001243 | Census | Yes | 38 | 0.097 | 248 | 17 | 0.069 | 0 |
| HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:2001243 | Census | Yes | 118 | 0.143 | 435 | 51 | 0.117 | 0 |
| HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | GO:2001243 | Not Cancer Driver | No | 24 | 0.037 | 200 | 13 | 0.065 | 0 |
| HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | GO:2001243 | Not Cancer Driver | No | 10 | 0.049 | 118 | 8 | 0.068 | 20 |
| HTRA2 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | GO:2001243 | Compendium | Yes | 44 | 0.096 | 127 | 9 | 0.071 | 2 |
| HYOU1 | HYOU1 | Q9Y4L1 | Hypoxia up-regulated protein 1 | chr11 | GO:2001243 | Not Cancer Driver | No | 132 | 0.132 | 373 | 47 | 0.126 | 0 |
| ING2 | ING2 | Q9H160 | Inhibitor of growth protein 2 | chr4 | GO:2001243 | Not Cancer Driver | No | 33 | 0.118 | 169 | 26 | 0.154 | 0 |
| INS | INS | P01308 | Insulin | chr11 | GO:2001243 | Not Cancer Driver | No | 15 | 0.136 | 5 | 1 | 0.2 | 22 |
| IVNS1ABP | IVNS1ABP | Q9Y6Y0 | Influenza virus NS1A-binding protein | chr1 | GO:2001243 | Not Cancer Driver | No | 85 | 0.132 | 90 | 12 | 0.133 | 0 |
| KDM1A_ENST00000356634 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | GO:2001243 | Not Cancer Driver | No | 67 | 0.079 | 291 | 28 | 0.096 | 3 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:2001243 | Not Cancer Driver | No | 519 | 0.205 | 90 | 17 | 0.189 | 23 |
| MAGEA3 | MAGEA3 | P43357 | Melanoma-associated antigen 3 | chrX | GO:2001243 | Not Cancer Driver | No | 79 | 0.252 | 103 | 18 | 0.175 | 0 |
| MAPK7 | MAPK7 | Q13164 | Mitogen-activated protein kinase 7 | chr17 | GO:2001243 | Not Cancer Driver | No | 92 | 0.113 | 490 | 50 | 0.102 | 0 |
| MAPK8IP1 | MAPK8IP1 | Q9UQF2 | C-Jun-amino-terminal kinase-interacting protein 1 | chr11 | GO:2001243 | Not Cancer Driver | No | 79 | 0.111 | 444 | 40 | 0.09 | 1 |
| MARCH7 | MARCHF7 | Q9H992 | E3 ubiquitin-protein ligase MARCHF7 | chr2 | GO:2001243 | Not Cancer Driver | No | 85 | 0.121 | 550 | 68 | 0.124 | 0 |
| MCL1 | MCL1 | Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | chr1 | GO:2001243 | Not Cancer Driver | No | 30 | 0.086 | 203 | 21 | 0.103 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:2001243 | Census, Compendium | Yes | 56 | 0.114 | 297 | 37 | 0.125 | 0 |
| MIF | MIF | P14174 | Macrophage migration inhibitory factor | chr22 | GO:2001243 | Not Cancer Driver | No | 4 | 0.035 | 0 | 0 | 0.0 | 0 |
| MMP9 | MMP9 | P14780 | Matrix metalloproteinase-9 | chr20 | GO:2001243 | Not Cancer Driver | No | 129 | 0.182 | 124 | 26 | 0.21 | 0 |
| MUC1_ENST00000611571 | MUC1 | P15941 | Mucin-1 | chr1 | GO:2001243 | Census | Yes | 40 | 0.032 | 1050 | 19 | 0.018 | 0 |
| NDUFA13 | NDUFA13 | Q9P0J0 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | chr19 | GO:2001243 | Not Cancer Driver | No | 29 | 0.201 | 24 | 4 | 0.167 | 1 |
| NDUFS3 | NDUFS3 | O75489 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | chr11 | GO:2001243 | Not Cancer Driver | No | 34 | 0.129 | 26 | 3 | 0.115 | 2 |
| NFE2L2 | NFE2L2 | Q16236 | Nuclear factor erythroid 2-related factor 2 | chr2 | GO:2001243 | Census, Compendium | Yes | 228 | 0.377 | 402 | 62 | 0.154 | 4 |
| NME5 | NME5 | P56597 | Nucleoside diphosphate kinase homolog 5 | chr5 | GO:2001243 | Not Cancer Driver | No | 17 | 0.08 | 6 | 0 | 0.0 | 0 |
| NOC2L | NOC2L | Q9Y3T9 | Nucleolar complex protein 2 homolog | chr1 | GO:2001243 | Not Cancer Driver | No | 77 | 0.103 | 281 | 31 | 0.11 | 0 |
| NOL3_ENST00000268605 | NOL3 | O60936 | Nucleolar protein 3 | chr16 | GO:2001243 | Not Cancer Driver | No | 20 | 0.096 | 179 | 17 | 0.095 | 2 |
| NONO | NONO | Q15233 | Non-POU domain-containing octamer-binding protein | chrX | GO:2001243 | Census, Compendium | Yes | 101 | 0.214 | 349 | 64 | 0.183 | 0 |
| OPA1_ENST00000392438 | OPA1 | O60313 | Dynamin-like 120 kDa protein, mitochondrial | chr3 | GO:2001243 | Not Cancer Driver | No | 114 | 0.119 | 131 | 17 | 0.13 | 60 |
| PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:2001243 | Not Cancer Driver | No | 11 | 0.058 | 30 | 0 | 0.0 | 5 |
| PARL | PARL | Q9H300 | Presenilins-associated rhomboid-like protein, mitochondrial | chr3 | GO:2001243 | Not Cancer Driver | No | 49 | 0.129 | 28 | 5 | 0.179 | 0 |
| PDX1 | PDX1 | P52945 | Pancreas/duodenum homeobox protein 1 | chr13 | GO:2001243 | Not Cancer Driver | No | 32 | 0.113 | 238 | 23 | 0.097 | 0 |
| PIK3CB_ENST00000477593 | PIK3CB | P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | chr3 | GO:2001243 | Census, Compendium | Yes | 150 | 0.14 | 42 | 4 | 0.095 | 0 |
| PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:2001243 | Not Cancer Driver | No | 57 | 0.098 | 99 | 13 | 0.131 | 23 |
| PLAUR | PLAUR | Q03405 | Urokinase plasminogen activator surface receptor | chr19 | GO:2001243 | Not Cancer Driver | No | 49 | 0.146 | 18 | 5 | 0.278 | 0 |
| PPIA | PPIA | P62937 | Peptidyl-prolyl cis-trans isomerase A | chr7 | GO:2001243 | Not Cancer Driver | No | 11 | 0.067 | 24 | 3 | 0.125 | 0 |
| PPIF | PPIF | P30405 | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | chr10 | GO:2001243 | Not Cancer Driver | No | 19 | 0.092 | 43 | 4 | 0.093 | 0 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:2001243 | Not Cancer Driver | No | 110 | 0.237 | 78 | 15 | 0.192 | 31 |
| PTGS2 | PTGS2 | P35354 | Prostaglandin G/H synthase 2 | chr1 | GO:2001243 | Not Cancer Driver | No | 105 | 0.174 | 30 | 5 | 0.167 | 0 |
| PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | GO:2001243 | Not Cancer Driver | No | 49 | 0.113 | 140 | 25 | 0.179 | 0 |
| PTTG1IP | PTTG1IP | P53801 | Pituitary tumor-transforming gene 1 protein-interacting protein | chr21 | GO:2001243 | Not Cancer Driver | No | 23 | 0.128 | 30 | 9 | 0.3 | 0 |
| RRM2B | RRM2B | Q7LG56 | Ribonucleoside-diphosphate reductase subunit M2 B | chr8 | GO:2001243 | Not Cancer Driver | No | 46 | 0.131 | 32 | 5 | 0.156 | 9 |
| RRN3 | RRN3 | Q9NYV6 | RNA polymerase I-specific transcription initiation factor RRN3 | chr16 | GO:2001243 | Not Cancer Driver | No | 66 | 0.101 | 115 | 15 | 0.13 | 0 |
| RTKN2 | RTKN2 | Q8IZC4 | Rhotekin-2 | chr10 | GO:2001243 | Not Cancer Driver | No | 71 | 0.117 | 158 | 21 | 0.133 | 0 |
| SELENOS | SELENOS | Q9BQE4 | Selenoprotein S | chr15 | GO:2001243 | Not Cancer Driver | No | 7 | 0.037 | 122 | 6 | 0.049 | 0 |
| SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:2001243 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:2001243 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
| SNAI1 | SNAI1 | O95863 | Zinc finger protein SNAI1 | chr20 | GO:2001243 | Not Cancer Driver | No | 52 | 0.197 | 97 | 11 | 0.113 | 0 |
| SNAI2_ENST00000020945 | SNAI2 | O43623 | Zinc finger protein SNAI2 | chr8 | GO:2001243 | Not Cancer Driver | No | 52 | 0.194 | 52 | 9 | 0.173 | 0 |
| SOD2_ENST00000367055 | SOD2 | P04179 | Superoxide dismutase [Mn], mitochondrial | chr6 | GO:2001243 | Not Cancer Driver | No | 32 | 0.144 | 25 | 5 | 0.2 | 0 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:2001243 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| SYVN1 | SYVN1 | Q86TM6 | E3 ubiquitin-protein ligase synoviolin | chr11 | GO:2001243 | Not Cancer Driver | No | 63 | 0.102 | 284 | 32 | 0.113 | 0 |
| TAF9 | TAF9 | Q16594 | Transcription initiation factor TFIID subunit 9 | chr5 | GO:2001243 | Not Cancer Driver | No | 25 | 0.095 | 203 | 19 | 0.094 | 0 |
| TAF9B | TAF9B | Q9HBM6 | Transcription initiation factor TFIID subunit 9B | chrX | GO:2001243 | Not Cancer Driver | No | 48 | 0.191 | 189 | 34 | 0.18 | 0 |
| TMBIM6_ENST00000549385 | TMBIM6 | P55061 | Bax inhibitor 1 | chr12 | GO:2001243 | Not Cancer Driver | No | 16 | 0.068 | 3 | 0 | 0.0 | 0 |
| TMEM161A | TMEM161A | Q9NX61 | Transmembrane protein 161A | chr19 | GO:2001243 | Not Cancer Driver | No | 49 | 0.102 | 22 | 8 | 0.364 | 0 |
| TPT1_ENST00000530705 | TPT1 | P13693 | Translationally-controlled tumor protein | chr13 | GO:2001243 | Not Cancer Driver | No | 17 | 0.099 | 43 | 6 | 0.14 | 0 |
| TRAP1 | TRAP1 | Q12931 | Heat shock protein 75 kDa, mitochondrial | chr16 | GO:2001243 | Not Cancer Driver | No | 74 | 0.105 | 110 | 11 | 0.1 | 0 |
| TRIAP1 | TRIAP1 | O43715 | TP53-regulated inhibitor of apoptosis 1 | chr12 | GO:2001243 | Not Cancer Driver | No | 9 | 0.118 | 20 | 1 | 0.05 | 0 |
| TRIM32 | TRIM32 | Q13049 | E3 ubiquitin-protein ligase TRIM32 | chr9 | GO:2001243 | Not Cancer Driver | No | 82 | 0.126 | 87 | 10 | 0.115 | 3 |
| TXNDC12 | TXNDC12 | O95881 | Thioredoxin domain-containing protein 12 | chr1 | GO:2001243 | Not Cancer Driver | No | 21 | 0.122 | 44 | 6 | 0.136 | 0 |
| URI1 | URI1 | O94763 | Unconventional prefoldin RPB5 interactor 1 | chr19 | GO:2001243 | Not Cancer Driver | No | 88 | 0.164 | 388 | 64 | 0.165 | 0 |
| USP47 | USP47 | Q96K76 | Ubiquitin carboxyl-terminal hydrolase 47 | chr11 | GO:2001243 | Not Cancer Driver | No | 137 | 0.1 | 425 | 39 | 0.092 | 0 |
| VDAC2_ENST00000543351 | VDAC2 | P45880 | Voltage-dependent anion-selective channel protein 2 | chr10 | GO:2001243 | Not Cancer Driver | No | 35 | 0.119 | 9 | 1 | 0.111 | 0 |
| VNN1 | VNN1 | O95497 | Pantetheinase | chr6 | GO:2001243 | Not Cancer Driver | No | 88 | 0.172 | 20 | 5 | 0.25 | 0 |
| WFS1_ENST00000503569 | WFS1 | O76024 | Wolframin | chr4 | GO:2001243 | Not Cancer Driver | No | 105 | 0.118 | 203 | 10 | 0.049 | 39 |
| XBP1 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:2001243 | Not Cancer Driver | No | 19 | 0.073 | 169 | 9 | 0.053 | 0 |
| YBX3 | YBX3 | P16989 | Y-box-binding protein 3 | chr12 | GO:2001243 | Not Cancer Driver | No | 49 | 0.132 | 359 | 47 | 0.131 | 0 |
| ZNF385A | ZNF385A | Q96PM9 | Zinc finger protein 385A | chr12 | GO:2001243 | Not Cancer Driver | No | 43 | 0.111 | 312 | 34 | 0.109 | 0 |