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Total number of protein in "GO:2001235" GO term:  103

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:2001235 Not Cancer Driver No 61 0.148 93 11 0.118 0
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:2001235 Not Cancer Driver No 127 0.102 17 1 0.059 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:2001235 Not Cancer Driver No 23 0.127 118 14 0.119 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:2001235 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:2001235 Census Yes 30 0.156 39 2 0.051 0
BBC3 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 GO:2001235 Not Cancer Driver No 20 0.077 253 20 0.079 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:2001235 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:2001235 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 GO:2001235 Census, Compendium Yes 421 0.458 899 408 0.454 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:2001235 Not Cancer Driver No 45 0.1 190 19 0.1 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 GO:2001235 Not Cancer Driver No 23 0.118 74 9 0.122 0
BMPR1B_ENST00000394931 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:2001235 Not Cancer Driver No 84 0.167 64 12 0.188 5
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:2001235 Not Cancer Driver No 7 0.033 0 0 0.0 0
CASP2 CASP2 P42575 Caspase-2 chr7 GO:2001235 Not Cancer Driver No 63 0.139 42 12 0.286 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:2001235 Not Cancer Driver No 30 0.169 2 0 0.0 0
CRADD_ENST00000332896 CRADD P78560 Death domain-containing protein CRADD chr12 GO:2001235 Not Cancer Driver No 35 0.176 45 5 0.111 1
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:2001235 Census Yes 126 0.139 268 35 0.131 4
CTSC CTSC P53634 Dipeptidyl peptidase 1 chr11 GO:2001235 Not Cancer Driver No 64 0.138 19 5 0.263 29
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:2001235 Not Cancer Driver No 45 0.134 4 0 0.0 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:2001235 Not Cancer Driver No 131 0.11 681 68 0.1 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:2001235 Census Yes 29 0.172 160 27 0.169 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:2001235 Not Cancer Driver No 67 0.091 212 23 0.108 7
EEF1E1 EEF1E1 O43324 Eukaryotic translation elongation factor 1 epsilon-1 chr6 GO:2001235 Not Cancer Driver No 27 0.155 11 1 0.091 0
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 GO:2001235 Not Cancer Driver No 37 0.24 21 5 0.238 5
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 GO:2001235 Not Cancer Driver No 83 0.128 241 34 0.141 0
FAS FAS P25445 Tumor necrosis factor receptor superfamily member 6 chr10 GO:2001235 Census, Compendium Yes 55 0.164 62 18 0.29 22
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:2001235 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:2001235 Census, Compendium Yes 322 0.455 230 38 0.165 0
FIS1 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 GO:2001235 Not Cancer Driver No 25 0.164 6 0 0.0 0
FLCN FLCN Q8NFG4 Folliculin chr17 GO:2001235 Census, Compendium Yes 59 0.102 157 19 0.121 5
GSDME_ENST00000409775 GSDME O60443 Gasdermin-E chr7 GO:2001235 Not Cancer Driver No 81 0.163 14 3 0.214 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:2001235 Compendium Yes 44 0.096 127 9 0.071 2
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:2001235 Not Cancer Driver No 46 0.246 0 0 0.0 0
IL19_ENST00000270218 IL19 Q9UHD0 Interleukin-19 chr1 GO:2001235 Not Cancer Driver No 16 0.09 0 0 0.0 0
IL20RA IL20RA Q9UHF4 Interleukin-20 receptor subunit alpha chr6 GO:2001235 Not Cancer Driver No 72 0.13 231 29 0.126 0
INCA1_ENST00000576820 INCA1 Q0VD86 Protein INCA1 chr17 GO:2001235 Not Cancer Driver No 18 0.076 195 14 0.072 0
ING5_ENST00000313552 ING5 Q8WYH8 Inhibitor of growth protein 5 chr2 GO:2001235 Not Cancer Driver No 25 0.104 119 9 0.076 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:2001235 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:2001235 Not Cancer Driver No 61 0.15 98 5 0.051 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:2001235 Census, Compendium Yes 136 0.12 59 5 0.085 5
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:2001235 Census Yes 86 0.169 94 13 0.138 1
MAGED1_ENST00000326587 MAGED1 Q9Y5V3 Melanoma-associated antigen D1 chrX GO:2001235 Not Cancer Driver No 131 0.168 457 71 0.155 0
MAL MAL P21145 Myelin and lymphocyte protein chr2 GO:2001235 Not Cancer Driver No 21 0.137 0 0 0.0 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:2001235 Not Cancer Driver No 59 0.139 90 8 0.089 0
MCL1 MCL1 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 chr1 GO:2001235 Not Cancer Driver No 30 0.086 203 21 0.103 0
MSX1 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:2001235 Not Cancer Driver No 39 0.129 197 16 0.081 7
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:2001235 Census, Compendium Yes 80 0.182 299 46 0.154 0
NACC2_ENST00000371753 NACC2 Q96BF6 Nucleus accumbens-associated protein 2 chr9 GO:2001235 Not Cancer Driver No 24 0.041 238 10 0.042 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:2001235 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:2001235 Not Cancer Driver No 89 0.234 88 19 0.216 0
NF1 NF1 P21359 Neurofibromin chr17 GO:2001235 Census, Compendium Yes 375 0.132 406 47 0.116 85
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:2001235 Not Cancer Driver No 155 0.172 685 120 0.175 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:2001235 Not Cancer Driver No 57 0.133 172 25 0.145 0
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:2001235 Not Cancer Driver No 35 0.15 171 16 0.094 0
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:2001235 Not Cancer Driver No 101 0.179 18 8 0.444 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:2001235 Not Cancer Driver No 10 0.122 82 10 0.122 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:2001235 Not Cancer Driver No 11 0.058 30 0 0.0 5
PEA15_ENST00000360472 PEA15 Q15121 Astrocytic phosphoprotein PEA-15 chr1 GO:2001235 Not Cancer Driver No 12 0.092 35 5 0.143 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 GO:2001235 Not Cancer Driver No 58 0.114 142 23 0.162 0
PLAGL2 PLAGL2 Q9UPG8 Zinc finger protein PLAGL2 chr20 GO:2001235 Not Cancer Driver No 62 0.125 204 29 0.142 0
PLEKHF1 PLEKHF1 Q96S99 Pleckstrin homology domain-containing family F member 1 chr19 GO:2001235 Not Cancer Driver No 30 0.108 65 10 0.154 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:2001235 Not Cancer Driver No 2 0.037 23 1 0.043 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 GO:2001235 Not Cancer Driver No 38 0.115 27 6 0.222 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:2001235 Census, Compendium Yes 179 0.304 0 0 0.0 4
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 GO:2001235 Not Cancer Driver No 72 0.12 17 1 0.059 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:2001235 Compendium Yes 79 0.117 43 9 0.209 0
PRKRA PRKRA O75569 Interferon-inducible double-stranded RNA-dependent protein kinase activator A chr2 GO:2001235 Not Cancer Driver No 41 0.131 104 12 0.115 1
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:2001235 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:2001235 Not Cancer Driver No 57 0.137 120 14 0.117 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:2001235 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAD9A RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:2001235 Not Cancer Driver No 34 0.087 135 7 0.052 0
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:2001235 Census, Compendium Yes 208 0.187 105 12 0.114 139
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:2001235 Not Cancer Driver No 66 0.127 295 39 0.132 0
RNF183_ENST00000297894 RNF183 Q96D59 E3 ubiquitin-protein ligase RNF183 chr9 GO:2001235 Not Cancer Driver No 22 0.115 29 1 0.034 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:2001235 Not Cancer Driver No 16 0.11 114 13 0.114 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:2001235 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 GO:2001235 Not Cancer Driver No 29 0.149 39 7 0.179 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 GO:2001235 Not Cancer Driver No 22 0.237 8 4 0.5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:2001235 Not Cancer Driver No 18 0.158 76 7 0.092 0
SEPT4_ENST00000317268 SEPTIN4 O43236 Septin-4 chr17 GO:2001235 Not Cancer Driver No 61 0.128 220 31 0.141 0
SERINC3_ENST00000255175 SERINC3 Q13530 Serine incorporator 3 chr20 GO:2001235 Not Cancer Driver No 73 0.154 38 9 0.237 0
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 GO:2001235 Census Yes 59 0.083 595 48 0.081 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:2001235 Not Cancer Driver No 40 0.127 39 7 0.179 0
SIAH1_ENST00000394725 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 GO:2001235 Not Cancer Driver No 35 0.124 28 2 0.071 5
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:2001235 Not Cancer Driver No 70 0.094 435 31 0.071 0
SKIL_ENST00000259119 SKIL P12757 Ski-like protein chr3 GO:2001235 Not Cancer Driver No 77 0.113 356 32 0.09 0
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:2001235 Not Cancer Driver No 19 0.053 318 16 0.05 4
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:2001235 Not Cancer Driver No 16 0.104 93 9 0.097 79
SRPX SRPX P78539 Sushi repeat-containing protein SRPX chrX GO:2001235 Not Cancer Driver No 71 0.153 60 10 0.167 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:2001235 Not Cancer Driver No 70 0.143 241 32 0.133 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:2001235 Not Cancer Driver No 70 0.144 231 30 0.13 0
STYXL1_ENST00000359697 STYXL1 Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 chr7 GO:2001235 Not Cancer Driver No 55 0.176 18 3 0.167 0
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:2001235 Not Cancer Driver No 86 0.171 23 3 0.13 15
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:2001235 Not Cancer Driver No 188 0.161 320 58 0.181 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:2001235 Not Cancer Driver No 43 0.204 3 1 0.333 5
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:2001235 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:2001235 Census, Compendium Yes 229 0.337 398 143 0.359 28
TPD52L1_ENST00000534000 TPD52L1 Q16890 Tumor protein D53 chr6 GO:2001235 Not Cancer Driver No 46 0.225 170 38 0.224 0
TRAF7 TRAF7 Q6Q0C0 E3 ubiquitin-protein ligase TRAF7 chr16 GO:2001235 Census Yes 76 0.113 120 14 0.117 4
TRIM39 TRIM39 Q9HCM9 E3 ubiquitin-protein ligase TRIM39 chr6 GO:2001235 Not Cancer Driver No 74 0.143 62 8 0.129 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 GO:2001235 Not Cancer Driver No 20 0.087 102 8 0.078 0
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 GO:2001235 Not Cancer Driver No 79 0.191 108 9 0.083 3
ZSWIM2 ZSWIM2 Q8NEG5 E3 ubiquitin-protein ligase ZSWIM2 chr2 GO:2001235 Not Cancer Driver No 189 0.299 85 30 0.353 0