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Total number of protein in "GO:2001141" GO term:  340

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:2001141 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:2001141 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADGRF1 ADGRF1 Q5T601 Adhesion G-protein coupled receptor F1 chr6 GO:2001141 Not Cancer Driver No 159 0.175 8 0 0.0 0
ADGRG3 ADGRG3 Q86Y34 Adhesion G protein-coupled receptor G3 chr16 GO:2001141 Not Cancer Driver No 87 0.158 42 5 0.119 0
ANKRD2 ANKRD2 Q9GZV1 Ankyrin repeat domain-containing protein 2 chr10 GO:2001141 Not Cancer Driver No 34 0.094 192 18 0.094 0
APLN APLN Q9ULZ1 Apelin chrX GO:2001141 Not Cancer Driver No 8 0.104 51 6 0.118 0
AR AR P10275 Androgen receptor chrX GO:2001141 Census, Compendium Yes 196 0.213 443 88 0.199 169
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:2001141 Census Yes 77 0.098 511 56 0.11 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:2001141 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:2001141 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:2001141 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:2001141 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 GO:2001141 Not Cancer Driver No 70 0.1 557 59 0.106 0
ATF7IP_ENST00000540793 ATF7IP Q6VMQ6 Activating transcription factor 7-interacting protein 1 chr12 GO:2001141 Compendium Yes 160 0.126 1136 139 0.122 0
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:2001141 Not Cancer Driver No 31 0.097 254 23 0.091 0
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:2001141 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:2001141 Census, Compendium Yes 120 0.139 619 88 0.142 4
BACH1_ENST00000286800 BACH1 O14867 Transcription regulator protein BACH1 chr21 GO:2001141 Not Cancer Driver No 105 0.143 328 39 0.119 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 GO:2001141 Not Cancer Driver No 57 0.099 571 57 0.1 7
BAZ1B_ENST00000404251 BAZ1B Q9UIG0 Tyrosine-protein kinase BAZ1B chr7 GO:2001141 Not Cancer Driver No 153 0.103 840 87 0.104 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 GO:2001141 Census, Compendium Yes 421 0.458 899 408 0.454 0
BHLHE41 BHLHE41 Q9C0J9 Class E basic helix-loop-helix protein 41 chr12 GO:2001141 Not Cancer Driver No 21 0.044 213 10 0.047 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:2001141 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:2001141 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:2001141 Census, Compendium Yes 66 0.124 21 0 0.0 8
BNC1 BNC1 Q01954 Zinc finger protein basonuclin-1 chr15 GO:2001141 Not Cancer Driver No 195 0.196 530 111 0.209 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 GO:2001141 Census, Compendium Yes 193 0.142 1182 172 0.146 0
BRDT_ENST00000362005 BRDT Q58F21 Bromodomain testis-specific protein chr1 GO:2001141 Not Cancer Driver No 173 0.183 703 121 0.172 0
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 GO:2001141 Not Cancer Driver No 90 0.133 399 45 0.113 4
BRF2 BRF2 Q9HAW0 Transcription factor IIIB 50 kDa subunit chr8 GO:2001141 Not Cancer Driver No 40 0.095 138 13 0.094 0
BUD31 BUD31 P41223 Protein BUD31 homolog chr7 GO:2001141 Not Cancer Driver No 20 0.139 32 4 0.125 0
C6orf203_ENST00000405204 MTRES1 Q9P0P8 Mitochondrial transcription rescue factor 1 chr6 GO:2001141 Not Cancer Driver No 28 0.117 45 4 0.089 0
CAMK1D CAMK1D Q8IU85 Calcium/calmodulin-dependent protein kinase type 1D chr10 GO:2001141 Not Cancer Driver No 90 0.234 42 14 0.333 0
CARF CARF Q8N187 Calcium-responsive transcription factor chr2 GO:2001141 Not Cancer Driver No 93 0.128 503 63 0.125 0
CC2D1A CC2D1A Q6P1N0 Coiled-coil and C2 domain-containing protein 1A chr19 GO:2001141 Not Cancer Driver No 146 0.154 718 100 0.139 0
CCDC22 CCDC22 O60826 Coiled-coil domain-containing protein 22 chrX GO:2001141 Not Cancer Driver No 62 0.099 243 18 0.074 2
CCNK CCNK O75909 Cyclin-K chr14 GO:2001141 Not Cancer Driver No 39 0.067 347 15 0.043 1
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 GO:2001141 Not Cancer Driver No 85 0.117 495 61 0.123 0
CD200_ENST00000315711 CD200 P41217 OX-2 membrane glycoprotein chr3 GO:2001141 Not Cancer Driver No 37 0.133 14 0 0.0 0
CDK14 CDK14 O94921 Cyclin-dependent kinase 14 chr7 GO:2001141 Not Cancer Driver No 93 0.198 154 21 0.136 0
CDK15 CDK15 Q96Q40 Cyclin-dependent kinase 15 chr2 GO:2001141 Not Cancer Driver No 66 0.152 35 4 0.114 0
CDK16_ENST00000357227 CDK16 Q00536 Cyclin-dependent kinase 16 chrX GO:2001141 Not Cancer Driver No 55 0.111 139 30 0.216 0
CDK17 CDK17 Q00537 Cyclin-dependent kinase 17 chr12 GO:2001141 Not Cancer Driver No 76 0.145 198 26 0.131 0
CDK18_ENST00000360066 CDK18 Q07002 Cyclin-dependent kinase 18 chr1 GO:2001141 Not Cancer Driver No 64 0.135 132 17 0.129 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:2001141 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 GO:2001141 Not Cancer Driver No 50 0.134 34 2 0.059 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:2001141 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:2001141 Not Cancer Driver No 3 0.009 276 2 0.007 0
CER1 CER1 O95813 Cerberus chr9 GO:2001141 Not Cancer Driver No 70 0.262 119 27 0.227 0
CHCHD10_ENST00000484558 CHCHD10 Q8WYQ3 Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial chr22 GO:2001141 Not Cancer Driver No 8 0.056 97 4 0.041 4
CHD6 CHD6 Q8TD26 Chromodomain-helicase-DNA-binding protein 6 chr20 GO:2001141 Not Cancer Driver No 393 0.145 1469 213 0.145 0
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 GO:2001141 Not Cancer Driver No 328 0.127 1411 148 0.105 0
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:2001141 Not Cancer Driver No 58 0.122 86 16 0.186 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:2001141 Not Cancer Driver No 23 0.085 230 18 0.078 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:2001141 Census Yes 25 0.076 277 23 0.083 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:2001141 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:2001141 Census Yes 68 0.131 372 50 0.134 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 GO:2001141 Not Cancer Driver No 96 0.208 338 67 0.198 1
CRTC1_ENST00000321949 CRTC1 Q6UUV9 CREB-regulated transcription coactivator 1 chr19 GO:2001141 Census, Compendium Yes 63 0.099 606 62 0.102 0
CRTC2 CRTC2 Q53ET0 CREB-regulated transcription coactivator 2 chr1 GO:2001141 Not Cancer Driver No 92 0.133 674 88 0.131 0
CRTC3 CRTC3 Q6UUV7 CREB-regulated transcription coactivator 3 chr15 GO:2001141 Census Yes 70 0.113 608 68 0.112 0
CTDP1 CTDP1 Q9Y5B0 RNA polymerase II subunit A C-terminal domain phosphatase chr18 GO:2001141 Not Cancer Driver No 121 0.126 624 87 0.139 0
CTNNBIP1_ENST00000377258 CTNNBIP1 Q9NSA3 Beta-catenin-interacting protein 1 chr1 GO:2001141 Not Cancer Driver No 8 0.099 64 7 0.109 0
DACH1_ENST00000619232 DACH1 Q9UI36 Dachshund homolog 1 chr13 GO:2001141 Not Cancer Driver No 157 0.207 641 134 0.209 0
DAND5 DAND5 Q8N907 DAN domain family member 5 chr19 GO:2001141 Not Cancer Driver No 32 0.169 26 3 0.115 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:2001141 Census Yes 29 0.172 160 27 0.169 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:2001141 Not Cancer Driver No 154 0.159 280 55 0.196 1
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:2001141 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:2001141 Census Yes 74 0.121 225 23 0.102 0
DEDD_ENST00000545495 DEDD O75618 Death effector domain-containing protein chr1 GO:2001141 Not Cancer Driver No 36 0.113 90 7 0.078 0
DEK DEK P35659 Protein DEK chr6 GO:2001141 Census Yes 47 0.125 297 41 0.138 0
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 GO:2001141 Not Cancer Driver No 53 0.075 125 12 0.096 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:2001141 Not Cancer Driver No 159 0.158 222 39 0.176 0
DLX5 DLX5 P56178 Homeobox protein DLX-5 chr7 GO:2001141 Not Cancer Driver No 71 0.246 223 57 0.256 1
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 GO:2001141 Census, Compendium Yes 35 0.103 196 26 0.133 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:2001141 Not Cancer Driver No 49 0.112 272 23 0.085 0
E2F4 E2F4 Q16254 Transcription factor E2F4 chr16 GO:2001141 Not Cancer Driver No 44 0.107 242 32 0.132 0
E2F6 E2F6 O75461 Transcription factor E2F6 chr2 GO:2001141 Not Cancer Driver No 20 0.071 105 10 0.095 0
E2F7 E2F7 Q96AV8 Transcription factor E2F7 chr12 GO:2001141 Not Cancer Driver No 122 0.134 554 70 0.126 0
EAPP EAPP Q56P03 E2F-associated phosphoprotein chr14 GO:2001141 Not Cancer Driver No 35 0.123 210 27 0.129 0
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:2001141 Not Cancer Driver No 78 0.144 501 72 0.144 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:2001141 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:2001141 Not Cancer Driver No 156 0.095 494 44 0.089 2
EIF4A2 EIF4A2 Q14240 Eukaryotic initiation factor 4A-II chr3 GO:2001141 Census Yes 77 0.189 27 14 0.519 0
ELL ELL P55199 RNA polymerase II elongation factor ELL chr19 GO:2001141 Census, Compendium Yes 67 0.108 446 53 0.119 0
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:2001141 Not Cancer Driver No 148 0.16 101 5 0.05 33
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:2001141 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 GO:2001141 Census, Compendium Yes 120 0.138 449 53 0.118 6
EPHA5_ENST00000273854 EPHA5 P54756 Ephrin type-A receptor 5 chr4 GO:2001141 Not Cancer Driver No 341 0.329 83 39 0.47 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:2001141 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:2001141 Not Cancer Driver No 211 0.141 829 117 0.141 9
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 GO:2001141 Not Cancer Driver No 90 0.208 35 7 0.2 4
ETS1_ENST00000319397 ETS1 P14921 Protein C-ets-1 chr11 GO:2001141 Not Cancer Driver No 68 0.154 78 9 0.115 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:2001141 Census, Compendium Yes 120 0.161 284 44 0.155 11
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 GO:2001141 Not Cancer Driver No 83 0.128 241 34 0.141 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:2001141 Not Cancer Driver No 18 0.062 183 5 0.027 0
FLNA FLNA P21333 Filamin-A chrX GO:2001141 Census Yes 416 0.157 1456 214 0.147 28
FOS FOS P01100 Protein c-Fos chr14 GO:2001141 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 GO:2001141 Not Cancer Driver No 24 0.089 271 24 0.089 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:2001141 Compendium Yes 70 0.153 258 34 0.132 0
FOXH1 FOXH1 O75593 Forkhead box protein H1 chr8 GO:2001141 Not Cancer Driver No 47 0.129 215 25 0.116 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:2001141 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:2001141 Not Cancer Driver No 38 0.088 186 16 0.086 10
G3BP2_ENST00000395719 G3BP2 Q9UN86 Ras GTPase-activating protein-binding protein 2 chr4 GO:2001141 Not Cancer Driver No 64 0.133 384 53 0.138 0
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:2001141 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:2001141 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA5 GATA5 Q9BWX5 Transcription factor GATA-5 chr20 GO:2001141 Not Cancer Driver No 40 0.101 268 24 0.09 9
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:2001141 Not Cancer Driver No 57 0.096 476 51 0.107 10
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 GO:2001141 Not Cancer Driver No 327 0.122 117 16 0.137 0
GFI1 GFI1 Q99684 Zinc finger protein Gfi-1 chr1 GO:2001141 Not Cancer Driver No 57 0.135 199 29 0.146 2
GINS1 GINS1 Q14691 DNA replication complex GINS protein PSF1 chr20 GO:2001141 Not Cancer Driver No 21 0.107 18 3 0.167 2
GINS2 GINS2 Q9Y248 DNA replication complex GINS protein PSF2 chr16 GO:2001141 Not Cancer Driver No 19 0.103 38 5 0.132 0
GINS3_ENST00000318129 GINS3 Q9BRX5 DNA replication complex GINS protein PSF3 chr16 GO:2001141 Not Cancer Driver No 36 0.167 14 0 0.0 0
GINS4 GINS4 Q9BRT9 DNA replication complex GINS protein SLD5 chr8 GO:2001141 Not Cancer Driver No 32 0.143 77 14 0.182 0
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 GO:2001141 Census, Compendium Yes 206 0.186 1015 184 0.181 0
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:2001141 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GLIS2 GLIS2 Q9BZE0 Zinc finger protein GLIS2 chr16 GO:2001141 Not Cancer Driver No 42 0.08 300 25 0.083 0
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 GO:2001141 Not Cancer Driver No 56 0.102 257 21 0.082 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:2001141 Not Cancer Driver No 25 0.136 77 12 0.156 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:2001141 Not Cancer Driver No 46 0.124 125 19 0.152 0
H2AFY2 MACROH2A2 Q9P0M6 Core histone macro-H2A.2 chr10 GO:2001141 Not Cancer Driver No 59 0.159 171 32 0.187 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:2001141 Not Cancer Driver No 47 0.217 124 29 0.234 0
HEATR1 HEATR1 Q9H583 HEAT repeat-containing protein 1 chr1 GO:2001141 Not Cancer Driver No 291 0.136 43 5 0.116 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 GO:2001141 Not Cancer Driver No 40 0.111 352 40 0.114 0
HEY1_ENST00000354724 HEY1 Q9Y5J3 Hairy/enhancer-of-split related with YRPW motif protein 1 chr8 GO:2001141 Census Yes 33 0.109 172 15 0.087 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:2001141 Not Cancer Driver No 64 0.19 179 26 0.145 0
HHEX HHEX Q03014 Hematopoietically-expressed homeobox protein HHEX chr10 GO:2001141 Not Cancer Driver No 23 0.085 193 21 0.109 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 GO:2001141 Not Cancer Driver No 37 0.106 77 9 0.117 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:2001141 Census Yes 118 0.143 435 51 0.117 0
HINFP HINFP Q9BQA5 Histone H4 transcription factor chr11 GO:2001141 Not Cancer Driver No 65 0.126 154 24 0.156 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:2001141 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:2001141 Not Cancer Driver No 46 0.16 81 13 0.16 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:2001141 Not Cancer Driver No 77 0.093 504 45 0.089 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:2001141 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:2001141 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:2001141 Not Cancer Driver No 73 0.112 282 35 0.124 0
ICE1 ICE1 Q9Y2F5 Little elongation complex subunit 1 chr5 GO:2001141 Not Cancer Driver No 360 0.159 1666 265 0.159 0
ICE2 ICE2 Q659A1 Little elongation complex subunit 2 chr15 GO:2001141 Not Cancer Driver No 107 0.109 399 45 0.113 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:2001141 Not Cancer Driver No 20 0.129 17 6 0.353 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:2001141 Not Cancer Driver No 14 0.104 52 7 0.135 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:2001141 Not Cancer Driver No 19 0.107 23 1 0.043 0
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:2001141 Not Cancer Driver No 49 0.153 84 12 0.143 0
IPPK IPPK Q9H8X2 Inositol-pentakisphosphate 2-kinase chr9 GO:2001141 Not Cancer Driver No 55 0.112 43 3 0.07 0
ITGA8 ITGA8 P53708 Integrin alpha-8 chr10 GO:2001141 Not Cancer Driver No 292 0.275 114 26 0.228 1
JUN JUN P05412 Transcription factor Jun chr1 GO:2001141 Census Yes 35 0.106 281 25 0.089 0
KDM2A KDM2A Q9Y2K7 Lysine-specific demethylase 2A chr11 GO:2001141 Not Cancer Driver No 131 0.113 387 48 0.124 0
KEAP1_ENST00000393623 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 GO:2001141 Census, Compendium Yes 237 0.38 57 12 0.211 0
KLF11 KLF11 O14901 Krueppel-like factor 11 chr2 GO:2001141 Not Cancer Driver No 57 0.111 308 38 0.123 2
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:2001141 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 GO:2001141 Compendium Yes 77 0.168 366 40 0.109 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 GO:2001141 Not Cancer Driver No 58 0.1 350 44 0.126 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:2001141 Not Cancer Driver No 162 0.362 277 115 0.415 0
LPAR5 LPAR5 Q9H1C0 Lysophosphatidic acid receptor 5 chr12 GO:2001141 Not Cancer Driver No 40 0.108 57 7 0.123 0
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:2001141 Not Cancer Driver No 94 0.098 190 24 0.126 0
LYAR_ENST00000452476 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 GO:2001141 Not Cancer Driver No 50 0.132 249 31 0.124 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:2001141 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAF1_ENST00000532522 MAF1 Q9H063 Repressor of RNA polymerase III transcription MAF1 homolog chr8 GO:2001141 Not Cancer Driver No 22 0.086 74 4 0.054 0
MAML1 MAML1 Q92585 Mastermind-like protein 1 chr5 GO:2001141 Not Cancer Driver No 102 0.1 1009 102 0.101 0
MAML2 MAML2 Q8IZL2 Mastermind-like protein 2 chr11 GO:2001141 Census, Compendium Yes 146 0.126 1156 146 0.126 0
MAML3 MAML3 Q96JK9 Mastermind-like protein 3 chr4 GO:2001141 Not Cancer Driver No 123 0.108 1119 123 0.11 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:2001141 Not Cancer Driver No 92 0.113 490 50 0.102 0
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 GO:2001141 Not Cancer Driver No 91 0.101 151 16 0.106 8
MBTPS2 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX GO:2001141 Not Cancer Driver No 63 0.121 16 4 0.25 9
MDFI MDFI Q99750 MyoD family inhibitor chr6 GO:2001141 Not Cancer Driver No 25 0.102 152 15 0.099 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:2001141 Not Cancer Driver No 75 0.154 483 74 0.153 46
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:2001141 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 GO:2001141 Not Cancer Driver No 76 0.11 446 42 0.094 0
METTL4 METTL4 Q8N3J2 N(6)-adenine-specific methyltransferase METTL4 chr18 GO:2001141 Not Cancer Driver No 61 0.129 34 4 0.118 0
MICAL2_ENST00000646065 MICAL2 O94851 [F-actin]-monooxygenase MICAL2 chr11 GO:2001141 Not Cancer Driver No 297 0.152 1191 179 0.15 0
MITF_ENST00000448226 MITF O75030 Microphthalmia-associated transcription factor chr3 GO:2001141 Census Yes 80 0.152 408 69 0.169 7
MORC1 MORC1 Q86VD1 MORC family CW-type zinc finger protein 1 chr3 GO:2001141 Not Cancer Driver No 300 0.305 252 77 0.306 0
MRTFA_ENST00000407029 MRTFA Q969V6 Myocardin-related transcription factor A chr22 GO:2001141 Census Yes 131 0.141 843 123 0.146 0
MRTFB MRTFB Q9ULH7 Myocardin-related transcription factor B chr16 GO:2001141 Not Cancer Driver No 124 0.114 1041 116 0.111 0
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:2001141 Not Cancer Driver No 27 0.101 168 14 0.083 4
MT3 MT3 P25713 Metallothionein-3 chr16 GO:2001141 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:2001141 Census, Compendium Yes 379 0.149 296 37 0.125 18
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:2001141 Census Yes 40 0.032 1050 19 0.018 0
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:2001141 Not Cancer Driver No 144 0.108 463 47 0.102 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:2001141 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:2001141 Not Cancer Driver No 284 0.303 853 263 0.308 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:2001141 Census Yes 45 0.141 246 33 0.134 0
NAB2 NAB2 Q15742 NGFI-A-binding protein 2 chr12 GO:2001141 Census Yes 67 0.128 395 51 0.129 0
NACC2_ENST00000371753 NACC2 Q96BF6 Nucleus accumbens-associated protein 2 chr9 GO:2001141 Not Cancer Driver No 24 0.041 238 10 0.042 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:2001141 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:2001141 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCL NCL P19338 Nucleolin chr2 GO:2001141 Not Cancer Driver No 85 0.12 569 68 0.12 0
NCOA1_ENST00000348332 NCOA1 Q15788 Nuclear receptor coactivator 1 chr2 GO:2001141 Census, Compendium Yes 188 0.13 1217 149 0.122 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:2001141 Not Cancer Driver No 150 0.114 711 79 0.111 0
NELFA_ENST00000411638 NELFA Q9H3P2 Negative elongation factor A chr4 GO:2001141 Not Cancer Driver No 68 0.129 373 58 0.155 0
NELFCD NELFCD Q8IXH7 Negative elongation factor C/D chr20 GO:2001141 Not Cancer Driver No 69 0.117 53 1 0.019 0
NELFE NELFE P18615 Negative elongation factor E chr6 GO:2001141 Not Cancer Driver No 47 0.124 352 45 0.128 0
NFATC3 NFATC3 Q12968 Nuclear factor of activated T-cells, cytoplasmic 3 chr16 GO:2001141 Not Cancer Driver No 112 0.104 730 80 0.11 0
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:2001141 Not Cancer Driver No 155 0.172 685 120 0.175 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:2001141 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFIB_ENST00000380959 NFIB O00712 Nuclear factor 1 B-type chr9 GO:2001141 Census Yes 63 0.15 254 36 0.142 3
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 GO:2001141 Compendium Yes 37 0.117 102 9 0.088 1
NFKBIB NFKBIB Q15653 NF-kappa-B inhibitor beta chr19 GO:2001141 Not Cancer Driver No 42 0.118 223 29 0.13 0
NFKBIE NFKBIE O00221 NF-kappa-B inhibitor epsilon chr6 GO:2001141 Census, Compendium Yes 41 0.082 284 16 0.056 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:2001141 Not Cancer Driver No 57 0.133 172 25 0.145 0
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:2001141 Not Cancer Driver No 48 0.148 181 22 0.122 55
NODAL NODAL Q96S42 Nodal homolog chr10 GO:2001141 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOL11 NOL11 Q9H8H0 Nucleolar protein 11 chr17 GO:2001141 Not Cancer Driver No 76 0.106 54 9 0.167 0
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:2001141 Not Cancer Driver No 59 0.123 391 41 0.105 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:2001141 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH4 NOTCH4 Q99466 Neurogenic locus notch homolog protein 4 chr6 GO:2001141 Not Cancer Driver No 336 0.168 464 79 0.17 0
NPAT NPAT Q14207 Protein NPAT chr11 GO:2001141 Not Cancer Driver No 134 0.094 1149 113 0.098 0
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:2001141 Not Cancer Driver No 90 0.159 218 33 0.151 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:2001141 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:2001141 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 GO:2001141 Not Cancer Driver No 92 0.118 362 37 0.102 12
OPRD1 OPRD1 P41143 Delta-type opioid receptor chr1 GO:2001141 Not Cancer Driver No 91 0.245 30 3 0.1 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:2001141 Not Cancer Driver No 11 0.058 30 0 0.0 5
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:2001141 Not Cancer Driver No 142 0.228 110 28 0.255 1
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:2001141 Census Yes 37 0.154 99 22 0.222 2
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:2001141 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHF8 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX GO:2001141 Not Cancer Driver No 154 0.145 603 93 0.154 1
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:2001141 Not Cancer Driver No 30 0.103 157 13 0.083 0
PKD1 PKD1 P98161 Polycystin-1 chr16 GO:2001141 Not Cancer Driver No 393 0.091 690 66 0.096 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:2001141 Not Cancer Driver No 113 0.117 375 35 0.093 10
POLR2K POLR2K P53803 DNA-directed RNA polymerases I, II, and III subunit RPABC4 chr8 GO:2001141 Not Cancer Driver No 10 0.172 11 1 0.091 0
POLR2L POLR2L P62875 DNA-directed RNA polymerases I, II, and III subunit RPABC5 chr11 GO:2001141 Not Cancer Driver No 10 0.149 0 0 0.0 0
POLR3C POLR3C Q9BUI4 DNA-directed RNA polymerase III subunit RPC3 chr1 GO:2001141 Not Cancer Driver No 60 0.112 161 21 0.13 0
POLR3F POLR3F Q9H1D9 DNA-directed RNA polymerase III subunit RPC6 chr20 GO:2001141 Not Cancer Driver No 20 0.063 55 5 0.091 0
POLR3G POLR3G O15318 DNA-directed RNA polymerase III subunit RPC7 chr5 GO:2001141 Not Cancer Driver No 28 0.126 187 15 0.08 0
POU5F1 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 GO:2001141 Census Yes 36 0.1 186 12 0.065 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:2001141 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:2001141 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:2001141 Census Yes 72 0.143 44 4 0.091 3
PPIL4 PPIL4 Q8WUA2 Peptidyl-prolyl cis-trans isomerase-like 4 chr6 GO:2001141 Not Cancer Driver No 62 0.126 237 34 0.143 0
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 GO:2001141 Not Cancer Driver No 22 0.103 0 0 0.0 0
PRIM2 PRIM2 P49643 DNA primase large subunit chr6 GO:2001141 Not Cancer Driver No 180 0.354 69 57 0.826 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:2001141 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:2001141 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:2001141 Compendium Yes 118 0.134 246 34 0.138 0
PRL PRL P01236 Prolactin chr6 GO:2001141 Not Cancer Driver No 49 0.216 22 1 0.045 0
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:2001141 Not Cancer Driver No 20 0.088 53 5 0.094 0
PWP1 PWP1 Q13610 Periodic tryptophan protein 1 homolog chr12 GO:2001141 Not Cancer Driver No 51 0.102 186 22 0.118 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:2001141 Census, Compendium Yes 70 0.152 167 14 0.084 0
RASL11A RASL11A Q6T310 Ras-like protein family member 11A chr13 GO:2001141 Not Cancer Driver No 31 0.128 40 6 0.15 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:2001141 Census, Compendium Yes 140 0.151 282 32 0.113 22
RBM15 RBM15 Q96T37 RNA-binding protein 15 chr1 GO:2001141 Census, Compendium Yes 118 0.121 686 91 0.133 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:2001141 Not Cancer Driver No 49 0.098 151 19 0.126 2
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:2001141 Not Cancer Driver No 132 0.133 495 71 0.143 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:2001141 Compendium Yes 75 0.136 400 48 0.12 0
RELN RELN P78509 Reelin chr7 GO:2001141 Not Cancer Driver No 761 0.22 107 19 0.178 7
REST REST Q13127 RE1-silencing transcription factor chr4 GO:2001141 Not Cancer Driver No 142 0.129 868 113 0.13 4
RGS14 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:2001141 Not Cancer Driver No 57 0.101 309 37 0.12 0
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 GO:2001141 Not Cancer Driver No 77 0.135 471 66 0.14 0
RNF8 RNF8 O76064 E3 ubiquitin-protein ligase RNF8 chr6 GO:2001141 Not Cancer Driver No 56 0.115 226 29 0.128 0
RPAP2 RPAP2 Q8IXW5 Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 chr1 GO:2001141 Not Cancer Driver No 56 0.092 293 25 0.085 0
RPRD1A RPRD1A Q96P16 Regulation of nuclear pre-mRNA domain-containing protein 1A chr18 GO:2001141 Not Cancer Driver No 49 0.157 86 16 0.186 0
RPRD1B RPRD1B Q9NQG5 Regulation of nuclear pre-mRNA domain-containing protein 1B chr20 GO:2001141 Not Cancer Driver No 34 0.104 155 16 0.103 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 GO:2001141 Not Cancer Driver No 94 0.128 178 32 0.18 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX GO:2001141 Compendium Yes 106 0.143 145 18 0.124 13
RPS6KA4 RPS6KA4 O75676 Ribosomal protein S6 kinase alpha-4 chr11 GO:2001141 Not Cancer Driver No 72 0.093 220 11 0.05 0
RPS6KA5 RPS6KA5 O75582 Ribosomal protein S6 kinase alpha-5 chr14 GO:2001141 Not Cancer Driver No 97 0.121 187 18 0.096 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:2001141 Not Cancer Driver No 176 0.132 241 21 0.087 0
RRP8 RRP8 O43159 Ribosomal RNA-processing protein 8 chr11 GO:2001141 Not Cancer Driver No 66 0.145 270 44 0.163 0
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:2001141 Not Cancer Driver No 83 0.159 447 73 0.163 47
RWDD1 RWDD1 Q9H446 RWD domain-containing protein 1 chr6 GO:2001141 Not Cancer Driver No 28 0.115 168 19 0.113 0
SCAF4 SCAF4 O95104 SR-related and CTD-associated factor 4 chr21 GO:2001141 Not Cancer Driver No 162 0.141 938 132 0.141 0
SCAF8_ENST00000367178 SCAF8 Q9UPN6 SR-related and CTD-associated factor 8 chr6 GO:2001141 Not Cancer Driver No 155 0.122 939 118 0.126 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:2001141 Not Cancer Driver No 74 0.154 147 26 0.177 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:2001141 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SF3B1 SF3B1 O75533 Splicing factor 3B subunit 1 chr2 GO:2001141 Census, Compendium Yes 244 0.187 477 80 0.168 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:2001141 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIK1 SIK1 P57059 Serine/threonine-protein kinase SIK1 chr21 GO:2001141 Not Cancer Driver No 80 0.102 330 30 0.091 3
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:2001141 Compendium Yes 172 0.135 617 73 0.118 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:2001141 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:2001141 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:2001141 Not Cancer Driver No 48 0.12 163 15 0.092 0
SLC38A3 SLC38A3 Q99624 Sodium-coupled neutral amino acid transporter 3 chr3 GO:2001141 Not Cancer Driver No 61 0.121 42 2 0.048 0
SLC40A1 SLC40A1 Q9NP59 Solute carrier family 40 member 1 chr2 GO:2001141 Not Cancer Driver No 63 0.11 48 3 0.062 12
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:2001141 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:2001141 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:2001141 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:2001141 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:2001141 Not Cancer Driver No 44 0.095 172 11 0.064 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:2001141 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:2001141 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMAD9 SMAD9 O15198 Mothers against decapentaplegic homolog 9 chr13 GO:2001141 Not Cancer Driver No 79 0.169 132 14 0.106 1
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:2001141 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 GO:2001141 Not Cancer Driver No 116 0.11 363 48 0.132 0
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:2001141 Census, Compendium Yes 64 0.166 141 35 0.248 3
SMO SMO Q99835 Smoothened homolog chr7 GO:2001141 Census, Compendium Yes 112 0.142 241 27 0.112 1
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:2001141 Compendium Yes 86 0.169 495 82 0.166 18
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:2001141 Not Cancer Driver No 46 0.17 187 34 0.182 0
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:2001141 Not Cancer Driver No 127 0.111 528 64 0.121 4
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 GO:2001141 Not Cancer Driver No 124 0.109 357 43 0.12 0
SRF SRF P11831 Serum response factor chr6 GO:2001141 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRI SRI P30626 Sorcin chr7 GO:2001141 Not Cancer Driver No 15 0.076 32 2 0.062 0
SSU72 SSU72 Q9NP77 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr1 GO:2001141 Not Cancer Driver No 18 0.093 65 3 0.046 0
SSU72P2 SSU72P2 A0A1W2PQD8 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr11 GO:2001141 Not Cancer Driver No 3 0.015 15 0 0.0 0
SSU72P3 SSU72P3 A0A1W2PQJ5 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr11 GO:2001141 Not Cancer Driver No 2 0.01 17 0 0.0 0
SSU72P8 SSU72P8 A0A1W2PR75 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr7 GO:2001141 Not Cancer Driver No 8 0.041 8 0 0.0 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:2001141 Census, Compendium Yes 110 0.143 152 15 0.099 19
STK36_ENST00000440309 STK36 Q9NRP7 Serine/threonine-protein kinase 36 chr2 GO:2001141 Not Cancer Driver No 167 0.127 250 36 0.144 0
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 GO:2001141 Not Cancer Driver No 121 0.122 659 83 0.126 2
SUFU SUFU Q9UMX1 Suppressor of fused homolog chr10 GO:2001141 Census Yes 55 0.114 199 19 0.095 2
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 GO:2001141 Not Cancer Driver No 10 0.099 76 7 0.092 0
SUPT4H1_ENST00000580947 SUPT4H1 P63272 Transcription elongation factor SPT4 chr17 GO:2001141 Not Cancer Driver No 15 0.128 0 0 0.0 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 GO:2001141 Not Cancer Driver No 165 0.152 572 87 0.152 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX GO:2001141 Not Cancer Driver No 59 0.143 15 1 0.067 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:2001141 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:2001141 Not Cancer Driver No 74 0.104 401 36 0.09 1
TBXT TBXT O15178 T-box transcription factor T chr6 GO:2001141 Not Cancer Driver No 110 0.253 253 69 0.273 1
TCERG1 TCERG1 O14776 Transcription elongation regulator 1 chr5 GO:2001141 Not Cancer Driver No 143 0.13 811 110 0.136 0
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:2001141 Not Cancer Driver No 21 0.198 33 7 0.212 0
TEAD1_ENST00000638666 TEAD1 P28347 Transcriptional enhancer factor TEF-1 chr11 GO:2001141 Not Cancer Driver No 52 0.122 157 24 0.153 1
TENM1_ENST00000371130 TENM1 Q9UKZ4 Teneurin-1 chrX GO:2001141 Not Cancer Driver No 728 0.267 482 164 0.34 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:2001141 Census Yes 110 0.097 212 16 0.075 31
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 GO:2001141 Not Cancer Driver No 77 0.176 275 44 0.16 4
TFDP1 TFDP1 Q14186 Transcription factor Dp-1 chr13 GO:2001141 Not Cancer Driver No 82 0.2 245 47 0.192 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:2001141 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:2001141 Not Cancer Driver No 63 0.152 47 8 0.17 3
THRA THRA P10827 Thyroid hormone receptor alpha chr17 GO:2001141 Not Cancer Driver No 69 0.141 207 30 0.145 2
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:2001141 Not Cancer Driver No 16 0.068 3 0 0.0 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:2001141 Census Yes 7 0.159 44 7 0.159 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:2001141 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:2001141 Not Cancer Driver No 48 0.104 229 28 0.122 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:2001141 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TSSK4_ENST00000287913 TSSK4 Q6SA08 Testis-specific serine/threonine-protein kinase 4 chr14 GO:2001141 Not Cancer Driver No 29 0.088 8 1 0.125 0
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 GO:2001141 Not Cancer Driver No 100 0.131 567 77 0.136 1
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 GO:2001141 Not Cancer Driver No 52 0.168 271 44 0.162 0
USF2 USF2 Q15853 Upstream stimulatory factor 2 chr19 GO:2001141 Not Cancer Driver No 30 0.087 326 29 0.089 0
UTP15 UTP15 Q8TED0 U3 small nucleolar RNA-associated protein 15 homolog chr5 GO:2001141 Not Cancer Driver No 49 0.095 39 4 0.103 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:2001141 Not Cancer Driver No 27 0.116 41 7 0.171 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 GO:2001141 Census, Compendium Yes 142 0.667 117 36 0.308 133
WDR43 WDR43 Q15061 WD repeat-containing protein 43 chr2 GO:2001141 Not Cancer Driver No 57 0.084 216 18 0.083 0
WDR75 WDR75 Q8IWA0 WD repeat-containing protein 75 chr2 GO:2001141 Not Cancer Driver No 67 0.081 87 7 0.08 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:2001141 Not Cancer Driver No 19 0.073 169 9 0.053 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:2001141 Not Cancer Driver No 37 0.089 336 26 0.077 2
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:2001141 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:2001141 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZNF143 ZNF143 P52747 Zinc finger protein 143 chr11 GO:2001141 Not Cancer Driver No 67 0.105 425 49 0.115 0
ZNF345_ENST00000612719 ZNF345 Q14585 Zinc finger protein 345 chr19 GO:2001141 Not Cancer Driver No 101 0.207 107 21 0.196 0
ZNF451 ZNF451 Q9Y4E5 E3 SUMO-protein ligase ZNF451 chr6 GO:2001141 Not Cancer Driver No 169 0.159 191 25 0.131 0
ZNF512B ZNF512B Q96KM6 Zinc finger protein 512B chr20 GO:2001141 Not Cancer Driver No 101 0.113 694 83 0.12 0
ZNF76 ZNF76 P36508 Zinc finger protein 76 chr6 GO:2001141 Not Cancer Driver No 66 0.116 330 39 0.118 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:2001141 Not Cancer Driver No 38 0.083 291 27 0.093 0