Total number of protein in "GO:2001022" GO term: 103
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | GO:2001022 | Not Cancer Driver | No | 112 | 0.299 | 43 | 5 | 0.116 | 5 |
| ACTL6A | ACTL6A | O96019 | Actin-like protein 6A | chr3 | GO:2001022 | Not Cancer Driver | No | 61 | 0.142 | 74 | 15 | 0.203 | 0 |
| ACTR2_ENST00000260641 | ACTR2 | P61160 | Actin-related protein 2 | chr2 | GO:2001022 | Not Cancer Driver | No | 51 | 0.129 | 6 | 2 | 0.333 | 0 |
| ANKRD1 | ANKRD1 | Q15327 | Ankyrin repeat domain-containing protein 1 | chr10 | GO:2001022 | Not Cancer Driver | No | 52 | 0.163 | 83 | 13 | 0.157 | 0 |
| ARID2 | ARID2 | Q68CP9 | AT-rich interactive domain-containing protein 2 | chr12 | GO:2001022 | Census, Compendium | Yes | 272 | 0.148 | 1143 | 141 | 0.123 | 0 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:2001022 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| ATR | ATR | Q13535 | Serine/threonine-protein kinase ATR | chr3 | GO:2001022 | Census, Compendium | Yes | 338 | 0.128 | 106 | 14 | 0.132 | 1 |
| BCLAF1 | BCLAF1 | Q9NYF8 | Bcl-2-associated transcription factor 1 | chr6 | GO:2001022 | Census, Compendium | Yes | 421 | 0.458 | 899 | 408 | 0.454 | 0 |
| BRD8 | BRD8 | Q9H0E9 | Bromodomain-containing protein 8 | chr5 | GO:2001022 | Not Cancer Driver | No | 189 | 0.153 | 934 | 147 | 0.157 | 0 |
| CCAR2 | CCAR2 | Q8N163 | Cell cycle and apoptosis regulator protein 2 | chr8 | GO:2001022 | Not Cancer Driver | No | 102 | 0.111 | 528 | 62 | 0.117 | 0 |
| DDX11 | DDX11 | Q96FC9 | ATP-dependent DNA helicase DDX11 | chr12 | GO:2001022 | Not Cancer Driver | No | 154 | 0.159 | 280 | 55 | 0.196 | 1 |
| DDX5 | DDX5 | P17844 | Probable ATP-dependent RNA helicase DDX5 | chr17 | GO:2001022 | Census | Yes | 74 | 0.121 | 225 | 23 | 0.102 | 0 |
| DMAP1_ENST00000315913 | DMAP1 | Q9NPF5 | DNA methyltransferase 1-associated protein 1 | chr1 | GO:2001022 | Not Cancer Driver | No | 49 | 0.105 | 269 | 28 | 0.104 | 0 |
| DTX3L | DTX3L | Q8TDB6 | E3 ubiquitin-protein ligase DTX3L | chr3 | GO:2001022 | Not Cancer Driver | No | 86 | 0.116 | 260 | 24 | 0.092 | 0 |
| EEF1E1 | EEF1E1 | O43324 | Eukaryotic translation elongation factor 1 epsilon-1 | chr6 | GO:2001022 | Not Cancer Driver | No | 27 | 0.155 | 11 | 1 | 0.091 | 0 |
| ENDOG | ENDOG | Q14249 | Endonuclease G, mitochondrial | chr9 | GO:2001022 | Not Cancer Driver | No | 11 | 0.037 | 61 | 1 | 0.016 | 0 |
| EP400 | EP400 | Q96L91 | E1A-binding protein p400 | chr12 | GO:2001022 | Not Cancer Driver | No | 397 | 0.126 | 2064 | 234 | 0.113 | 0 |
| EPC1 | EPC1 | Q9H2F5 | Enhancer of polycomb homolog 1 | chr10 | GO:2001022 | Not Cancer Driver | No | 104 | 0.124 | 515 | 68 | 0.132 | 0 |
| EPC2 | EPC2 | Q52LR7 | Enhancer of polycomb homolog 2 | chr2 | GO:2001022 | Not Cancer Driver | No | 95 | 0.118 | 583 | 67 | 0.115 | 0 |
| ERCC6 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | GO:2001022 | Not Cancer Driver | No | 211 | 0.141 | 829 | 117 | 0.141 | 9 |
| FAM168A | FAM168A | Q92567 | Protein FAM168A | chr11 | GO:2001022 | Not Cancer Driver | No | 17 | 0.07 | 139 | 11 | 0.079 | 0 |
| FANCB | FANCB | Q8NB91 | Fanconi anemia group B protein | chrX | GO:2001022 | Not Cancer Driver | No | 109 | 0.127 | 24 | 5 | 0.208 | 0 |
| FBH1_ENST00000362091 | FBH1 | Q8NFZ0 | F-box DNA helicase 1 | chr10 | GO:2001022 | Not Cancer Driver | No | 139 | 0.133 | 192 | 32 | 0.167 | 0 |
| FMN2 | FMN2 | Q9NZ56 | Formin-2 | chr1 | GO:2001022 | Not Cancer Driver | No | 614 | 0.357 | 1322 | 475 | 0.359 | 0 |
| FMR1 | FMR1 | Q06787 | Synaptic functional regulator FMR1 | chrX | GO:2001022 | Not Cancer Driver | No | 124 | 0.196 | 327 | 70 | 0.214 | 3 |
| FOXM1_ENST00000359843 | FOXM1 | Q08050 | Forkhead box protein M1 | chr12 | GO:2001022 | Not Cancer Driver | No | 97 | 0.127 | 601 | 73 | 0.121 | 0 |
| FUS | FUS | P35637 | RNA-binding protein FUS | chr16 | GO:2001022 | Census | Yes | 51 | 0.097 | 524 | 51 | 0.097 | 20 |
| FXR1 | FXR1 | P51114 | Fragile X mental retardation syndrome-related protein 1 | chr3 | GO:2001022 | Not Cancer Driver | No | 88 | 0.142 | 312 | 53 | 0.17 | 0 |
| FXR2 | FXR2 | P51116 | Fragile X mental retardation syndrome-related protein 2 | chr17 | GO:2001022 | Not Cancer Driver | No | 68 | 0.101 | 388 | 42 | 0.108 | 0 |
| HDAC10 | HDAC10 | Q969S8 | Polyamine deacetylase HDAC10 | chr22 | GO:2001022 | Not Cancer Driver | No | 67 | 0.1 | 121 | 11 | 0.091 | 0 |
| HDGFL2 | HDGFL2 | Q7Z4V5 | Hepatoma-derived growth factor-related protein 2 | chr19 | GO:2001022 | Not Cancer Driver | No | 59 | 0.088 | 622 | 57 | 0.092 | 0 |
| HIC1 | HIC1 | Q14526 | Hypermethylated in cancer 1 protein | chr17 | GO:2001022 | Not Cancer Driver | No | 24 | 0.033 | 361 | 6 | 0.017 | 0 |
| HMGA2_ENST00000403681 | HMGA2 | P52926 | High mobility group protein HMGI-C | chr12 | GO:2001022 | Census | Yes | 12 | 0.11 | 109 | 12 | 0.11 | 0 |
| HMGB1_ENST00000405805 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:2001022 | Not Cancer Driver | No | 25 | 0.116 | 203 | 20 | 0.099 | 0 |
| ING3 | ING3 | Q9NXR8 | Inhibitor of growth protein 3 | chr7 | GO:2001022 | Not Cancer Driver | No | 44 | 0.105 | 292 | 32 | 0.11 | 1 |
| ING4 | ING4 | Q9UNL4 | Inhibitor of growth protein 4 | chr12 | GO:2001022 | Not Cancer Driver | No | 31 | 0.124 | 108 | 15 | 0.139 | 0 |
| KAT5_ENST00000377046 | KAT5 | Q92993 | Histone acetyltransferase KAT5 | chr11 | GO:2001022 | Not Cancer Driver | No | 65 | 0.127 | 173 | 21 | 0.121 | 3 |
| KDM4D_ENST00000610872 | KDM4D | Q6B0I6 | Lysine-specific demethylase 4D | chr11 | GO:2001022 | Not Cancer Driver | No | 78 | 0.149 | 215 | 33 | 0.153 | 0 |
| KHDC3L | KHDC3L | Q587J8 | KH domain-containing protein 3 | chr6 | GO:2001022 | Not Cancer Driver | No | 68 | 0.313 | 121 | 43 | 0.355 | 0 |
| KMT5B_ENST00000615954 | KMT5B | Q4FZB7 | Histone-lysine N-methyltransferase KMT5B | chr11 | GO:2001022 | Not Cancer Driver | No | 147 | 0.166 | 659 | 113 | 0.171 | 0 |
| KMT5C | KMT5C | Q86Y97 | Histone-lysine N-methyltransferase KMT5C | chr19 | GO:2001022 | Not Cancer Driver | No | 37 | 0.08 | 142 | 9 | 0.063 | 0 |
| MAD2L2 | MAD2L2 | Q9UI95 | Mitotic spindle assembly checkpoint protein MAD2B | chr1 | GO:2001022 | Not Cancer Driver | No | 22 | 0.104 | 0 | 0 | 0.0 | 1 |
| MAP3K20 | MAP3K20 | Q9NYL2 | Mitogen-activated protein kinase kinase kinase 20 | chr2 | GO:2001022 | Not Cancer Driver | No | 101 | 0.126 | 294 | 41 | 0.139 | 1 |
| MBTD1_ENST00000415868 | MBTD1 | Q05BQ5 | MBT domain-containing protein 1 | chr17 | GO:2001022 | Not Cancer Driver | No | 66 | 0.105 | 119 | 8 | 0.067 | 0 |
| MEAF6_ENST00000296214 | MEAF6 | Q9HAF1 | Chromatin modification-related protein MEAF6 | chr1 | GO:2001022 | Not Cancer Driver | No | 22 | 0.115 | 171 | 21 | 0.123 | 0 |
| MMS19 | MMS19 | Q96T76 | MMS19 nucleotide excision repair protein homolog | chr10 | GO:2001022 | Not Cancer Driver | No | 73 | 0.071 | 11 | 0 | 0.0 | 0 |
| MORF4L1 | MORF4L1 | Q9UBU8 | Mortality factor 4-like protein 1 | chr15 | GO:2001022 | Not Cancer Driver | No | 43 | 0.119 | 163 | 17 | 0.104 | 0 |
| MORF4L2_ENST00000433176 | MORF4L2 | Q15014 | Mortality factor 4-like protein 2 | chrX | GO:2001022 | Not Cancer Driver | No | 44 | 0.153 | 136 | 21 | 0.154 | 0 |
| MRGBP | MRGBP | Q9NV56 | MRG/MORF4L-binding protein | chr20 | GO:2001022 | Not Cancer Driver | No | 27 | 0.132 | 147 | 23 | 0.156 | 0 |
| MRNIP | MRNIP | Q6NTE8 | MRN complex-interacting protein | chr5 | GO:2001022 | Not Cancer Driver | No | 44 | 0.128 | 268 | 35 | 0.131 | 0 |
| MSX1 | MSX1 | P28360 | Homeobox protein MSX-1 | chr4 | GO:2001022 | Not Cancer Driver | No | 39 | 0.129 | 197 | 16 | 0.081 | 7 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:2001022 | Census, Compendium | Yes | 80 | 0.182 | 299 | 46 | 0.154 | 0 |
| NACC2_ENST00000371753 | NACC2 | Q96BF6 | Nucleus accumbens-associated protein 2 | chr9 | GO:2001022 | Not Cancer Driver | No | 24 | 0.041 | 238 | 10 | 0.042 | 0 |
| NKX3-1 | NKX3-1 | Q99801 | Homeobox protein Nkx-3.1 | chr8 | GO:2001022 | Not Cancer Driver | No | 35 | 0.15 | 171 | 16 | 0.094 | 0 |
| NSMCE1 | NSMCE1 | Q8WV22 | Non-structural maintenance of chromosomes element 1 homolog | chr16 | GO:2001022 | Not Cancer Driver | No | 40 | 0.15 | 31 | 8 | 0.258 | 0 |
| NSMCE4A | NSMCE4A | Q9NXX6 | Non-structural maintenance of chromosomes element 4 homolog A | chr10 | GO:2001022 | Not Cancer Driver | No | 17 | 0.044 | 200 | 5 | 0.025 | 0 |
| OOEP | OOEP | A6NGQ2 | Oocyte-expressed protein homolog | chr6 | GO:2001022 | Not Cancer Driver | No | 46 | 0.309 | 48 | 14 | 0.292 | 0 |
| PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:2001022 | Not Cancer Driver | No | 119 | 0.117 | 320 | 34 | 0.106 | 0 |
| PARP3_ENST00000431474 | PARP3 | Q9Y6F1 | Protein mono-ADP-ribosyltransferase PARP3 | chr3 | GO:2001022 | Not Cancer Driver | No | 70 | 0.131 | 269 | 38 | 0.141 | 0 |
| PARP9 | PARP9 | Q8IXQ6 | Protein mono-ADP-ribosyltransferase PARP9 | chr3 | GO:2001022 | Not Cancer Driver | No | 110 | 0.129 | 45 | 3 | 0.067 | 0 |
| PAXIP1 | PAXIP1 | Q6ZW49 | PAX-interacting protein 1 | chr7 | GO:2001022 | Not Cancer Driver | No | 120 | 0.112 | 461 | 39 | 0.085 | 0 |
| PIAS4 | PIAS4 | Q8N2W9 | E3 SUMO-protein ligase PIAS4 | chr19 | GO:2001022 | Not Cancer Driver | No | 58 | 0.114 | 142 | 23 | 0.162 | 0 |
| PLA2R1 | PLA2R1 | Q13018 | Secretory phospholipase A2 receptor | chr2 | GO:2001022 | Not Cancer Driver | No | 202 | 0.138 | 39 | 2 | 0.051 | 0 |
| PMAIP1 | PMAIP1 | Q13794 | Phorbol-12-myristate-13-acetate-induced protein 1 | chr18 | GO:2001022 | Not Cancer Driver | No | 2 | 0.037 | 23 | 1 | 0.043 | 0 |
| PNKP | PNKP | Q96T60 | Bifunctional polynucleotide phosphatase/kinase | chr19 | GO:2001022 | Not Cancer Driver | No | 53 | 0.102 | 177 | 23 | 0.13 | 4 |
| POGZ | POGZ | Q7Z3K3 | Pogo transposable element with ZNF domain | chr1 | GO:2001022 | Not Cancer Driver | No | 157 | 0.111 | 746 | 78 | 0.105 | 0 |
| PRKCD_ENST00000330452 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | GO:2001022 | Compendium | Yes | 79 | 0.117 | 43 | 9 | 0.209 | 0 |
| PRKCG | PRKCG | P05129 | Protein kinase C gamma type | chr19 | GO:2001022 | Not Cancer Driver | No | 172 | 0.247 | 151 | 43 | 0.285 | 5 |
| PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:2001022 | Not Cancer Driver | No | 538 | 0.13 | 421 | 61 | 0.145 | 2 |
| PYHIN1 | PYHIN1 | Q6K0P9 | Pyrin and HIN domain-containing protein 1 | chr1 | GO:2001022 | Not Cancer Driver | No | 174 | 0.354 | 291 | 99 | 0.34 | 0 |
| RAD51AP1 | RAD51AP1 | Q96B01 | RAD51-associated protein 1 | chr12 | GO:2001022 | Not Cancer Driver | No | 46 | 0.131 | 335 | 43 | 0.128 | 0 |
| RAD9A | RAD9A | Q99638 | Cell cycle checkpoint control protein RAD9A | chr11 | GO:2001022 | Not Cancer Driver | No | 34 | 0.087 | 135 | 7 | 0.052 | 0 |
| RBBP8_ENST00000327155 | RBBP8 | Q99708 | DNA endonuclease RBBP8 | chr18 | GO:2001022 | Not Cancer Driver | No | 99 | 0.11 | 750 | 76 | 0.101 | 1 |
| RIF1 | RIF1 | Q5UIP0 | Telomere-associated protein RIF1 | chr2 | GO:2001022 | Not Cancer Driver | No | 287 | 0.116 | 1355 | 164 | 0.121 | 0 |
| RPL26 | RPL26 | P61254 | 60S ribosomal protein L26 | chr17 | GO:2001022 | Not Cancer Driver | No | 16 | 0.11 | 114 | 13 | 0.114 | 0 |
| RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:2001022 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
| RUVBL1 | RUVBL1 | Q9Y265 | RuvB-like 1 | chr3 | GO:2001022 | Not Cancer Driver | No | 54 | 0.118 | 67 | 7 | 0.104 | 0 |
| RUVBL2 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | GO:2001022 | Not Cancer Driver | No | 62 | 0.134 | 100 | 13 | 0.13 | 0 |
| SETMAR | SETMAR | Q53H47 | Histone-lysine N-methyltransferase SETMAR | chr3 | GO:2001022 | Not Cancer Driver | No | 62 | 0.091 | 154 | 12 | 0.078 | 0 |
| SHLD1 | SHLD1 | Q8IYI0 | Shieldin complex subunit 1 | chr20 | GO:2001022 | Not Cancer Driver | No | 30 | 0.146 | 116 | 20 | 0.172 | 0 |
| SHLD2_ENST00000298784 | SHLD2 | Q86V20 | Shieldin complex subunit 2 | chr10 | GO:2001022 | Not Cancer Driver | No | 84 | 0.101 | 157 | 14 | 0.089 | 0 |
| SHLD3 | SHLD3 | Q6ZNX1 | Shieldin complex subunit 3 | chr5 | GO:2001022 | Not Cancer Driver | No | 3 | 0.012 | 81 | 1 | 0.012 | 0 |
| SKIL_ENST00000259119 | SKIL | P12757 | Ski-like protein | chr3 | GO:2001022 | Not Cancer Driver | No | 77 | 0.113 | 356 | 32 | 0.09 | 0 |
| SLF1 | SLF1 | Q9BQI6 | SMC5-SMC6 complex localization factor protein 1 | chr5 | GO:2001022 | Not Cancer Driver | No | 104 | 0.098 | 167 | 12 | 0.072 | 0 |
| SLF2_ENST00000238961 | SLF2 | Q8IX21 | SMC5-SMC6 complex localization factor protein 2 | chr10 | GO:2001022 | Not Cancer Driver | No | 112 | 0.095 | 725 | 76 | 0.105 | 0 |
| SMCHD1 | SMCHD1 | A6NHR9 | Structural maintenance of chromosomes flexible hinge domain-containing protein 1 | chr18 | GO:2001022 | Not Cancer Driver | No | 240 | 0.12 | 342 | 45 | 0.132 | 45 |
| SPIDR | SPIDR | Q14159 | DNA repair-scaffolding protein | chr8 | GO:2001022 | Not Cancer Driver | No | 101 | 0.11 | 329 | 20 | 0.061 | 0 |
| SPIRE1 | SPIRE1 | Q08AE8 | Protein spire homolog 1 | chr18 | GO:2001022 | Not Cancer Driver | No | 78 | 0.103 | 414 | 48 | 0.116 | 0 |
| SPIRE2 | SPIRE2 | Q8WWL2 | Protein spire homolog 2 | chr16 | GO:2001022 | Not Cancer Driver | No | 79 | 0.111 | 344 | 43 | 0.125 | 0 |
| SPRED1 | SPRED1 | Q7Z699 | Sprouty-related, EVH1 domain-containing protein 1 | chr15 | GO:2001022 | Not Cancer Driver | No | 71 | 0.16 | 194 | 35 | 0.18 | 2 |
| SPRED2 | SPRED2 | Q7Z698 | Sprouty-related, EVH1 domain-containing protein 2 | chr2 | GO:2001022 | Not Cancer Driver | No | 73 | 0.175 | 228 | 43 | 0.189 | 0 |
| TIMELESS | TIMELESS | Q9UNS1 | Protein timeless homolog | chr12 | GO:2001022 | Not Cancer Driver | No | 154 | 0.127 | 367 | 51 | 0.139 | 0 |
| TRRAP | TRRAP | Q9Y4A5 | Transformation/transcription domain-associated protein | chr7 | GO:2001022 | Census, Compendium | Yes | 554 | 0.144 | 402 | 59 | 0.147 | 8 |
| UBE2N | UBE2N | P61088 | Ubiquitin-conjugating enzyme E2 N | chr12 | GO:2001022 | Not Cancer Driver | No | 25 | 0.164 | 24 | 3 | 0.125 | 0 |
| UBE2V2 | UBE2V2 | Q15819 | Ubiquitin-conjugating enzyme E2 variant 2 | chr8 | GO:2001022 | Not Cancer Driver | No | 22 | 0.152 | 76 | 12 | 0.158 | 0 |
| VPS72 | VPS72 | Q15906 | Vacuolar protein sorting-associated protein 72 homolog | chr1 | GO:2001022 | Not Cancer Driver | No | 43 | 0.118 | 329 | 37 | 0.112 | 0 |
| WAS | WAS | P42768 | Wiskott-Aldrich syndrome protein | chrX | GO:2001022 | Census, Compendium | Yes | 75 | 0.149 | 400 | 55 | 0.138 | 30 |
| WDR48 | WDR48 | Q8TAF3 | WD repeat-containing protein 48 | chr3 | GO:2001022 | Not Cancer Driver | No | 61 | 0.09 | 125 | 19 | 0.152 | 0 |
| WRAP53 | WRAP53 | Q9BUR4 | Telomerase Cajal body protein 1 | chr17 | GO:2001022 | Not Cancer Driver | No | 66 | 0.12 | 232 | 29 | 0.125 | 4 |
| XRCC1 | XRCC1 | P18887 | DNA repair protein XRCC1 | chr19 | GO:2001022 | Not Cancer Driver | No | 85 | 0.134 | 426 | 53 | 0.124 | 1 |
| YEATS4 | YEATS4 | O95619 | YEATS domain-containing protein 4 | chr12 | GO:2001022 | Not Cancer Driver | No | 23 | 0.101 | 17 | 1 | 0.059 | 0 |
| ZCWPW1 | ZCWPW1 | Q9H0M4 | Zinc finger CW-type PWWP domain protein 1 | chr7 | GO:2001022 | Not Cancer Driver | No | 90 | 0.139 | 456 | 61 | 0.134 | 0 |
| ZNF385A | ZNF385A | Q96PM9 | Zinc finger protein 385A | chr12 | GO:2001022 | Not Cancer Driver | No | 43 | 0.111 | 312 | 34 | 0.109 | 0 |