Total number of protein in "GO:2001021" GO term: 56
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACKR3 | ACKR3 | P25106 | Atypical chemokine receptor 3 | chr2 | GO:2001021 | Census, Compendium | Yes | 78 | 0.215 | 0 | 0 | 0.0 | 1 |
| ATAD5 | ATAD5 | Q96QE3 | ATPase family AAA domain-containing protein 5 | chr17 | GO:2001021 | Not Cancer Driver | No | 200 | 0.108 | 1075 | 112 | 0.104 | 0 |
| AUNIP_ENST00000374298 | AUNIP | Q9H7T9 | Aurora kinase A and ninein-interacting protein | chr1 | GO:2001021 | Not Cancer Driver | No | 23 | 0.064 | 341 | 21 | 0.062 | 0 |
| BCL2L1 | BCL2L1 | Q07817 | Bcl-2-like protein 1 | chr20 | GO:2001021 | Not Cancer Driver | No | 29 | 0.124 | 55 | 3 | 0.055 | 0 |
| BCL2_ENST00000333681 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:2001021 | Census, Compendium | Yes | 24 | 0.1 | 72 | 5 | 0.069 | 0 |
| BID_ENST00000551952 | BID | P55957 | BH3-interacting domain death agonist | chr22 | GO:2001021 | Not Cancer Driver | No | 23 | 0.118 | 74 | 9 | 0.122 | 0 |
| CCAR2 | CCAR2 | Q8N163 | Cell cycle and apoptosis regulator protein 2 | chr8 | GO:2001021 | Not Cancer Driver | No | 102 | 0.111 | 528 | 62 | 0.117 | 0 |
| CD44 | CD44 | P16070 | CD44 antigen | chr11 | GO:2001021 | Not Cancer Driver | No | 75 | 0.101 | 542 | 60 | 0.111 | 0 |
| CD74 | CD74 | P04233 | HLA class II histocompatibility antigen gamma chain | chr5 | GO:2001021 | Census | Yes | 31 | 0.105 | 185 | 20 | 0.108 | 0 |
| CDKN2D_ENST00000335766 | CDKN2D | P55273 | Cyclin-dependent kinase 4 inhibitor D | chr19 | GO:2001021 | Not Cancer Driver | No | 17 | 0.102 | 44 | 3 | 0.068 | 0 |
| CHEK2_ENST00000405598 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | GO:2001021 | Census, Compendium | Yes | 335 | 0.617 | 157 | 130 | 0.828 | 13 |
| CLU_ENST00000523500 | CLU | P10909 | Clusterin | chr8 | GO:2001021 | Not Cancer Driver | No | 69 | 0.154 | 156 | 27 | 0.173 | 0 |
| CXCL12_ENST00000374429 | CXCL12 | P48061 | Stromal cell-derived factor 1 | chr10 | GO:2001021 | Not Cancer Driver | No | 16 | 0.172 | 0 | 0 | 0.0 | 0 |
| CYREN | CYREN | Q9BWK5 | Cell cycle regulator of non-homologous end joining | chr7 | GO:2001021 | Not Cancer Driver | No | 24 | 0.153 | 128 | 19 | 0.148 | 0 |
| DDIAS | DDIAS | Q8IXT1 | DNA damage-induced apoptosis suppressor protein | chr11 | GO:2001021 | Not Cancer Driver | No | 125 | 0.125 | 370 | 59 | 0.159 | 0 |
| DDX39B_ENST00000458640 | DDX39B | Q13838 | Spliceosome RNA helicase DDX39B | chr6 | GO:2001021 | Not Cancer Driver | No | 49 | 0.114 | 34 | 8 | 0.235 | 0 |
| DYRK1A_ENST00000644942 | DYRK1A | Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | chr21 | GO:2001021 | Not Cancer Driver | No | 135 | 0.177 | 447 | 73 | 0.163 | 0 |
| DYRK3 | DYRK3 | O43781 | Dual specificity tyrosine-phosphorylation-regulated kinase 3 | chr1 | GO:2001021 | Not Cancer Driver | No | 87 | 0.148 | 193 | 20 | 0.104 | 0 |
| ELL3 | ELL3 | Q9HB65 | RNA polymerase II elongation factor ELL3 | chr15 | GO:2001021 | Not Cancer Driver | No | 50 | 0.126 | 186 | 13 | 0.07 | 0 |
| ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:2001021 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
| ERCC4 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:2001021 | Census | Yes | 120 | 0.131 | 225 | 27 | 0.12 | 15 |
| ERCC6 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | GO:2001021 | Not Cancer Driver | No | 211 | 0.141 | 829 | 117 | 0.141 | 9 |
| FBXO5 | FBXO5 | Q9UKT4 | F-box only protein 5 | chr6 | GO:2001021 | Not Cancer Driver | No | 48 | 0.107 | 113 | 13 | 0.115 | 0 |
| HMGA2_ENST00000403681 | HMGA2 | P52926 | High mobility group protein HMGI-C | chr12 | GO:2001021 | Census | Yes | 12 | 0.11 | 109 | 12 | 0.11 | 0 |
| HSF1 | HSF1 | Q00613 | Heat shock factor protein 1 | chr8 | GO:2001021 | Not Cancer Driver | No | 59 | 0.112 | 335 | 37 | 0.11 | 0 |
| ING2 | ING2 | Q9H160 | Inhibitor of growth protein 2 | chr4 | GO:2001021 | Not Cancer Driver | No | 33 | 0.118 | 169 | 26 | 0.154 | 0 |
| KDM1A_ENST00000356634 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | GO:2001021 | Not Cancer Driver | No | 67 | 0.079 | 291 | 28 | 0.096 | 3 |
| MARCH7 | MARCHF7 | Q9H992 | E3 ubiquitin-protein ligase MARCHF7 | chr2 | GO:2001021 | Not Cancer Driver | No | 85 | 0.121 | 550 | 68 | 0.124 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:2001021 | Census, Compendium | Yes | 56 | 0.114 | 297 | 37 | 0.125 | 0 |
| MIF | MIF | P14174 | Macrophage migration inhibitory factor | chr22 | GO:2001021 | Not Cancer Driver | No | 4 | 0.035 | 0 | 0 | 0.0 | 0 |
| MUC1_ENST00000611571 | MUC1 | P15941 | Mucin-1 | chr1 | GO:2001021 | Census | Yes | 40 | 0.032 | 1050 | 19 | 0.018 | 0 |
| NUDT16L1 | NUDT16L1 | Q9BRJ7 | Tudor-interacting repair regulator protein | chr16 | GO:2001021 | Not Cancer Driver | No | 16 | 0.076 | 6 | 0 | 0.0 | 0 |
| OGG1_ENST00000344629 | OGG1 | O15527 | N-glycosylase/DNA lyase | chr3 | GO:2001021 | Not Cancer Driver | No | 37 | 0.107 | 71 | 12 | 0.169 | 0 |
| PPP1R10 | PPP1R10 | Q96QC0 | Serine/threonine-protein phosphatase 1 regulatory subunit 10 | chr6 | GO:2001021 | Not Cancer Driver | No | 114 | 0.121 | 798 | 100 | 0.125 | 0 |
| PSMD10 | PSMD10 | O75832 | 26S proteasome non-ATPase regulatory subunit 10 | chrX | GO:2001021 | Not Cancer Driver | No | 20 | 0.088 | 53 | 5 | 0.094 | 0 |
| PTTG1IP | PTTG1IP | P53801 | Pituitary tumor-transforming gene 1 protein-interacting protein | chr21 | GO:2001021 | Not Cancer Driver | No | 23 | 0.128 | 30 | 9 | 0.3 | 0 |
| RTEL1_ENST00000370018 | RTEL1 | Q9NZ71 | Regulator of telomere elongation helicase 1 | chr20 | GO:2001021 | Not Cancer Driver | No | 144 | 0.118 | 474 | 64 | 0.135 | 14 |
| SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:2001021 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:2001021 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
| SNAI1 | SNAI1 | O95863 | Zinc finger protein SNAI1 | chr20 | GO:2001021 | Not Cancer Driver | No | 52 | 0.197 | 97 | 11 | 0.113 | 0 |
| SNAI2_ENST00000020945 | SNAI2 | O43623 | Zinc finger protein SNAI2 | chr8 | GO:2001021 | Not Cancer Driver | No | 52 | 0.194 | 52 | 9 | 0.173 | 0 |
| TAF9 | TAF9 | Q16594 | Transcription initiation factor TFIID subunit 9 | chr5 | GO:2001021 | Not Cancer Driver | No | 25 | 0.095 | 203 | 19 | 0.094 | 0 |
| TAF9B | TAF9B | Q9HBM6 | Transcription initiation factor TFIID subunit 9B | chrX | GO:2001021 | Not Cancer Driver | No | 48 | 0.191 | 189 | 34 | 0.18 | 0 |
| TERF2 | TERF2 | Q15554 | Telomeric repeat-binding factor 2 | chr16 | GO:2001021 | Not Cancer Driver | No | 33 | 0.061 | 361 | 20 | 0.055 | 0 |
| TFIP11_ENST00000407148 | TFIP11 | Q9UBB9 | Tuftelin-interacting protein 11 | chr22 | GO:2001021 | Not Cancer Driver | No | 87 | 0.104 | 331 | 39 | 0.118 | 0 |
| THOC1 | THOC1 | Q96FV9 | THO complex subunit 1 | chr18 | GO:2001021 | Not Cancer Driver | No | 55 | 0.084 | 280 | 26 | 0.093 | 0 |
| THOC5_ENST00000397872 | THOC5 | Q13769 | THO complex subunit 5 homolog | chr22 | GO:2001021 | Not Cancer Driver | No | 88 | 0.129 | 173 | 25 | 0.145 | 0 |
| TMEM161A | TMEM161A | Q9NX61 | Transmembrane protein 161A | chr19 | GO:2001021 | Not Cancer Driver | No | 49 | 0.102 | 22 | 8 | 0.364 | 0 |
| TPT1_ENST00000530705 | TPT1 | P13693 | Translationally-controlled tumor protein | chr13 | GO:2001021 | Not Cancer Driver | No | 17 | 0.099 | 43 | 6 | 0.14 | 0 |
| TRIAP1 | TRIAP1 | O43715 | TP53-regulated inhibitor of apoptosis 1 | chr12 | GO:2001021 | Not Cancer Driver | No | 9 | 0.118 | 20 | 1 | 0.05 | 0 |
| TRIM32 | TRIM32 | Q13049 | E3 ubiquitin-protein ligase TRIM32 | chr9 | GO:2001021 | Not Cancer Driver | No | 82 | 0.126 | 87 | 10 | 0.115 | 3 |
| TWIST1 | TWIST1 | Q15672 | Twist-related protein 1 | chr7 | GO:2001021 | Not Cancer Driver | No | 23 | 0.114 | 132 | 11 | 0.083 | 7 |
| USP47 | USP47 | Q96K76 | Ubiquitin carboxyl-terminal hydrolase 47 | chr11 | GO:2001021 | Not Cancer Driver | No | 137 | 0.1 | 425 | 39 | 0.092 | 0 |
| XRCC1 | XRCC1 | P18887 | DNA repair protein XRCC1 | chr19 | GO:2001021 | Not Cancer Driver | No | 85 | 0.134 | 426 | 53 | 0.124 | 1 |
| YJU2 | YJU2 | Q9BW85 | Splicing factor YJU2 | chr19 | GO:2001021 | Not Cancer Driver | No | 29 | 0.09 | 233 | 13 | 0.056 | 0 |
| ZNF385A | ZNF385A | Q96PM9 | Zinc finger protein 385A | chr12 | GO:2001021 | Not Cancer Driver | No | 43 | 0.111 | 312 | 34 | 0.109 | 0 |