Total number of protein in "GO:1990782" GO term: 53
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVR1_ENST00000434821 | ACVR1 | Q04771 | Activin receptor type-1 | chr2 | GO:1990782 | Census, Compendium | Yes | 78 | 0.153 | 21 | 8 | 0.381 | 8 |
| BANK1 | BANK1 | Q8NDB2 | B-cell scaffold protein with ankyrin repeats | chr4 | GO:1990782 | Not Cancer Driver | No | 150 | 0.191 | 394 | 73 | 0.185 | 0 |
| BLNK | BLNK | Q8WV28 | B-cell linker protein | chr10 | GO:1990782 | Not Cancer Driver | No | 74 | 0.162 | 376 | 61 | 0.162 | 0 |
| BMPR2 | BMPR2 | Q13873 | Bone morphogenetic protein receptor type-2 | chr2 | GO:1990782 | Compendium | Yes | 141 | 0.136 | 601 | 70 | 0.116 | 19 |
| CASS4 | CASS4 | Q9NQ75 | Cas scaffolding protein family member 4 | chr20 | GO:1990782 | Not Cancer Driver | No | 204 | 0.26 | 496 | 137 | 0.276 | 0 |
| CD247 | CD247 | P20963 | T-cell surface glycoprotein CD3 zeta chain | chr1 | GO:1990782 | Not Cancer Driver | No | 33 | 0.201 | 91 | 24 | 0.264 | 0 |
| CD4 | CD4 | P01730 | T-cell surface glycoprotein CD4 | chr12 | GO:1990782 | Not Cancer Driver | No | 69 | 0.151 | 56 | 11 | 0.196 | 0 |
| CDH5 | CDH5 | P33151 | Cadherin-5 | chr16 | GO:1990782 | Not Cancer Driver | No | 144 | 0.184 | 305 | 55 | 0.18 | 0 |
| CEACAM1 | CEACAM1 | P13688 | Carcinoembryonic antigen-related cell adhesion molecule 1 | chr19 | GO:1990782 | Not Cancer Driver | No | 64 | 0.122 | 241 | 25 | 0.104 | 0 |
| CEACAM20 | CEACAM20 | Q6UY09 | Carcinoembryonic antigen-related cell adhesion molecule 20 | chr19 | GO:1990782 | Not Cancer Driver | No | 86 | 0.144 | 182 | 30 | 0.165 | 0 |
| CEACAM3 | CEACAM3 | P40198 | Carcinoembryonic antigen-related cell adhesion molecule 3 | chr19 | GO:1990782 | Not Cancer Driver | No | 59 | 0.234 | 56 | 16 | 0.286 | 0 |
| CEACAM4 | CEACAM4 | O75871 | Carcinoembryonic antigen-related cell adhesion molecule 4 | chr19 | GO:1990782 | Not Cancer Driver | No | 64 | 0.262 | 59 | 15 | 0.254 | 0 |
| CRK | CRK | P46108 | Adapter molecule crk | chr17 | GO:1990782 | Not Cancer Driver | No | 30 | 0.099 | 197 | 23 | 0.117 | 0 |
| DOK2 | DOK2 | O60496 | Docking protein 2 | chr8 | GO:1990782 | Not Cancer Driver | No | 58 | 0.141 | 254 | 31 | 0.122 | 0 |
| DSCAM | DSCAM | O60469 | Down syndrome cell adhesion molecule | chr21 | GO:1990782 | Not Cancer Driver | No | 652 | 0.324 | 603 | 201 | 0.333 | 0 |
| DUSP22_ENST00000344450 | DUSP22 | Q9NRW4 | Dual specificity protein phosphatase 22 | chr6 | GO:1990782 | Not Cancer Driver | No | 84 | 0.457 | 0 | 0 | 0.0 | 0 |
| DUSP3 | DUSP3 | P51452 | Dual specificity protein phosphatase 3 | chr17 | GO:1990782 | Not Cancer Driver | No | 21 | 0.114 | 4 | 1 | 0.25 | 0 |
| EPHA4_ENST00000409938 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | GO:1990782 | Not Cancer Driver | No | 182 | 0.185 | 140 | 24 | 0.171 | 0 |
| FCRL3_ENST00000368184 | FCRL3 | Q96P31 | Fc receptor-like protein 3 | chr1 | GO:1990782 | Not Cancer Driver | No | 193 | 0.263 | 217 | 44 | 0.203 | 0 |
| FRS2 | FRS2 | Q8WU20 | Fibroblast growth factor receptor substrate 2 | chr12 | GO:1990782 | Not Cancer Driver | No | 69 | 0.136 | 415 | 58 | 0.14 | 0 |
| FRS3_ENST00000259748 | FRS3 | O43559 | Fibroblast growth factor receptor substrate 3 | chr6 | GO:1990782 | Not Cancer Driver | No | 77 | 0.157 | 388 | 58 | 0.149 | 0 |
| GAB2 | GAB2 | Q9UQC2 | GRB2-associated-binding protein 2 | chr11 | GO:1990782 | Not Cancer Driver | No | 85 | 0.126 | 537 | 73 | 0.136 | 0 |
| GJA1 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | GO:1990782 | Not Cancer Driver | No | 86 | 0.225 | 110 | 26 | 0.236 | 50 |
| GP6_ENST00000417454 | GP6 | Q9HCN6 | Platelet glycoprotein VI | chr19 | GO:1990782 | Not Cancer Driver | No | 57 | 0.168 | 122 | 21 | 0.172 | 2 |
| GRM5 | GRM5 | P41594 | Metabotropic glutamate receptor 5 | chr11 | GO:1990782 | Not Cancer Driver | No | 312 | 0.257 | 323 | 51 | 0.158 | 0 |
| HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | GO:1990782 | Census, Compendium | Yes | 106 | 0.145 | 257 | 37 | 0.144 | 0 |
| IRS1 | IRS1 | P35568 | Insulin receptor substrate 1 | chr2 | GO:1990782 | Not Cancer Driver | No | 161 | 0.13 | 1072 | 133 | 0.124 | 2 |
| ITGB1_ENST00000302278 | ITGB1 | P05556 | Integrin beta-1 | chr10 | GO:1990782 | Not Cancer Driver | No | 103 | 0.129 | 84 | 10 | 0.119 | 0 |
| KHDRBS1 | KHDRBS1 | Q07666 | KH domain-containing, RNA-binding, signal transduction-associated protein 1 | chr1 | GO:1990782 | Not Cancer Driver | No | 53 | 0.12 | 362 | 43 | 0.119 | 0 |
| NEDD9 | NEDD9 | Q14511 | Enhancer of filamentation 1 | chr6 | GO:1990782 | Not Cancer Driver | No | 106 | 0.127 | 516 | 72 | 0.14 | 0 |
| NOX4 | NOX4 | Q9NPH5 | NADPH oxidase 4 | chr11 | GO:1990782 | Not Cancer Driver | No | 123 | 0.213 | 0 | 0 | 0.0 | 0 |
| PHYHIP | PHYHIP | Q92561 | Phytanoyl-CoA hydroxylase-interacting protein | chr8 | GO:1990782 | Not Cancer Driver | No | 44 | 0.133 | 25 | 4 | 0.16 | 0 |
| PIK3R1 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:1990782 | Census, Compendium | Yes | 154 | 0.213 | 268 | 61 | 0.228 | 2 |
| PLCG2 | PLCG2 | P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | chr16 | GO:1990782 | Not Cancer Driver | No | 248 | 0.196 | 142 | 30 | 0.211 | 1 |
| PRR7_ENST00000502922 | PRR7 | Q8TB68 | Proline-rich protein 7 | chr5 | GO:1990782 | Not Cancer Driver | No | 10 | 0.036 | 199 | 6 | 0.03 | 0 |
| PSG1_ENST00000436291 | PSG1 | P11464 | Pregnancy-specific beta-1-glycoprotein 1 | chr19 | GO:1990782 | Not Cancer Driver | No | 168 | 0.401 | 78 | 29 | 0.372 | 0 |
| PSG3 | PSG3 | Q16557 | Pregnancy-specific beta-1-glycoprotein 3 | chr19 | GO:1990782 | Not Cancer Driver | No | 139 | 0.325 | 66 | 17 | 0.258 | 0 |
| PSG4 | PSG4 | Q00888 | Pregnancy-specific beta-1-glycoprotein 4 | chr19 | GO:1990782 | Not Cancer Driver | No | 153 | 0.365 | 36 | 9 | 0.25 | 0 |
| PSG6 | PSG6 | Q00889 | Pregnancy-specific beta-1-glycoprotein 6 | chr19 | GO:1990782 | Not Cancer Driver | No | 156 | 0.359 | 23 | 14 | 0.609 | 0 |
| PSG7_ENST00000406070 | PSG7 | Q13046 | Putative pregnancy-specific beta-1-glycoprotein 7 | chr19 | GO:1990782 | Not Cancer Driver | No | 139 | 0.332 | 75 | 29 | 0.387 | 0 |
| PSG8 | PSG8 | Q9UQ74 | Pregnancy-specific beta-1-glycoprotein 8 | chr19 | GO:1990782 | Not Cancer Driver | No | 165 | 0.387 | 47 | 19 | 0.404 | 0 |
| PSG9 | PSG9 | Q00887 | Pregnancy-specific beta-1-glycoprotein 9 | chr19 | GO:1990782 | Not Cancer Driver | No | 125 | 0.293 | 40 | 8 | 0.2 | 0 |
| PTPN11_ENST00000351677 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:1990782 | Census, Compendium | Yes | 129 | 0.218 | 260 | 38 | 0.146 | 60 |
| SH2B1 | SH2B1 | Q9NRF2 | SH2B adapter protein 1 | chr16 | GO:1990782 | Not Cancer Driver | No | 98 | 0.13 | 612 | 84 | 0.137 | 0 |
| SH2B3 | SH2B3 | Q9UQQ2 | SH2B adapter protein 3 | chr12 | GO:1990782 | Census, Compendium | Yes | 48 | 0.083 | 333 | 19 | 0.057 | 0 |
| SHC1_ENST00000368445 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | GO:1990782 | Not Cancer Driver | No | 84 | 0.144 | 397 | 58 | 0.146 | 0 |
| SIRPA_ENST00000400068 | SIRPA | P78324 | Tyrosine-protein phosphatase non-receptor type substrate 1 | chr20 | GO:1990782 | Census, Compendium | Yes | 96 | 0.19 | 281 | 51 | 0.181 | 0 |
| STAP1_ENST00000396225 | STAP1 | Q9ULZ2 | Signal-transducing adaptor protein 1 | chr4 | GO:1990782 | Not Cancer Driver | No | 66 | 0.224 | 103 | 18 | 0.175 | 0 |
| TJP2_ENST00000377245 | TJP2 | Q9UDY2 | Tight junction protein ZO-2 | chr9 | GO:1990782 | Not Cancer Driver | No | 149 | 0.125 | 919 | 113 | 0.123 | 1 |
| TRADD | TRADD | Q15628 | Tumor necrosis factor receptor type 1-associated DEATH domain protein | chr16 | GO:1990782 | Not Cancer Driver | No | 26 | 0.083 | 74 | 5 | 0.068 | 0 |
| TRAT1 | TRAT1 | Q6PIZ9 | T-cell receptor-associated transmembrane adapter 1 | chr3 | GO:1990782 | Not Cancer Driver | No | 86 | 0.462 | 129 | 67 | 0.519 | 0 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:1990782 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |
| TRIM6_ENST00000278302 | TRIM6 | Q9C030 | Tripartite motif-containing protein 6 | chr11 | GO:1990782 | Not Cancer Driver | No | 86 | 0.176 | 47 | 15 | 0.319 | 0 |