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Total number of protein in "GO:1990391" GO term:  34

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:1990391 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATP23 ATP23 Q9Y6H3 Mitochondrial inner membrane protease ATP23 homolog chr12 GO:1990391 Not Cancer Driver No 26 0.106 25 3 0.12 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:1990391 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:1990391 Census, Compendium Yes 457 0.134 1542 225 0.146 46
CETN2 CETN2 P41208 Centrin-2 chrX GO:1990391 Not Cancer Driver No 33 0.192 97 11 0.113 0
DCLRE1C DCLRE1C Q96SD1 Protein artemis chr10 GO:1990391 Not Cancer Driver No 76 0.11 277 26 0.094 3
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:1990391 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 GO:1990391 Census, Compendium Yes 92 0.118 208 22 0.106 2
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:1990391 Census Yes 120 0.131 225 27 0.12 15
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 GO:1990391 Census, Compendium Yes 176 0.121 181 14 0.077 3
FANCI FANCI Q9NVI1 Fanconi anemia group I protein chr15 GO:1990391 Not Cancer Driver No 161 0.121 129 20 0.155 2
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:1990391 Not Cancer Driver No 67 0.079 291 28 0.096 3
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:1990391 Not Cancer Driver No 134 0.147 63 10 0.159 2
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:1990391 Census Yes 92 0.122 208 22 0.106 85
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:1990391 Census Yes 92 0.099 37 4 0.108 70
MSH3 MSH3 P20585 DNA mismatch repair protein Msh3 chr5 GO:1990391 Not Cancer Driver No 100 0.088 211 20 0.095 0
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:1990391 Census Yes 154 0.113 386 41 0.106 6
NHEJ1 NHEJ1 Q9H9Q4 Non-homologous end-joining factor 1 chr2 GO:1990391 Not Cancer Driver No 35 0.117 83 8 0.096 2
PALB2 PALB2 Q86YC2 Partner and localizer of BRCA2 chr16 GO:1990391 Census Yes 124 0.105 769 77 0.1 1
PAXX PAXX Q9BUH6 Protein PAXX chr9 GO:1990391 Not Cancer Driver No 22 0.108 121 17 0.14 0
PHF21A PHF21A Q96BD5 PHD finger protein 21A chr11 GO:1990391 Not Cancer Driver No 83 0.122 546 68 0.125 0
PMS2 PMS2 P54278 Mismatch repair endonuclease PMS2 chr7 GO:1990391 Census, Compendium Yes 117 0.136 331 44 0.133 9
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:1990391 Not Cancer Driver No 538 0.13 421 61 0.145 2
RAD23B RAD23B P54727 UV excision repair protein RAD23 homolog B chr9 GO:1990391 Not Cancer Driver No 54 0.132 324 41 0.127 0
RCOR1 RCOR1 Q9UKL0 REST corepressor 1 chr14 GO:1990391 Not Cancer Driver No 47 0.097 324 28 0.086 0
SWSAP1 SWSAP1 Q6NVH7 ATPase SWSAP1 chr19 GO:1990391 Not Cancer Driver No 26 0.114 104 14 0.135 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 GO:1990391 Not Cancer Driver No 227 0.115 1632 190 0.116 0
XPA XPA P23025 DNA repair protein complementing XP-A cells chr9 GO:1990391 Census Yes 27 0.099 121 13 0.107 5
XPC XPC Q01831 DNA repair protein complementing XP-C cells chr3 GO:1990391 Census, Compendium Yes 88 0.094 479 48 0.1 2
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:1990391 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC4 XRCC4 Q13426 DNA repair protein XRCC4 chr5 GO:1990391 Not Cancer Driver No 47 0.14 171 31 0.181 3
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:1990391 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:1990391 Not Cancer Driver No 66 0.108 140 12 0.086 0
ZSWIM7_ENST00000472495 ZSWIM7 Q19AV6 Zinc finger SWIM domain-containing protein 7 chr17 GO:1990391 Not Cancer Driver No 8 0.057 0 0 0.0 0