Total number of protein in "GO:1905114" GO term: 69
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ARHGEF19 | ARHGEF19 | Q8IW93 | Rho guanine nucleotide exchange factor 19 | chr1 | GO:1905114 | Not Cancer Driver | No | 82 | 0.102 | 365 | 36 | 0.099 | 0 |
| BMP2 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:1905114 | Not Cancer Driver | No | 73 | 0.184 | 139 | 26 | 0.187 | 0 |
| BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:1905114 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
| C3 | C3 | P01024 | Complement C3 | chr19 | GO:1905114 | Not Cancer Driver | No | 337 | 0.203 | 287 | 50 | 0.174 | 12 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:1905114 | Not Cancer Driver | No | 39 | 0.204 | 23 | 2 | 0.087 | 1 |
| CDH3 | CDH3 | P22223 | Cadherin-3 | chr16 | GO:1905114 | Not Cancer Driver | No | 87 | 0.105 | 488 | 52 | 0.107 | 2 |
| CELSR1 | CELSR1 | Q9NYQ6 | Cadherin EGF LAG seven-pass G-type receptor 1 | chr22 | GO:1905114 | Not Cancer Driver | No | 390 | 0.129 | 880 | 107 | 0.122 | 4 |
| CELSR2 | CELSR2 | Q9HCU4 | Cadherin EGF LAG seven-pass G-type receptor 2 | chr1 | GO:1905114 | Not Cancer Driver | No | 348 | 0.119 | 990 | 115 | 0.116 | 0 |
| CELSR3 | CELSR3 | Q9NYQ7 | Cadherin EGF LAG seven-pass G-type receptor 3 | chr3 | GO:1905114 | Not Cancer Driver | No | 395 | 0.119 | 1315 | 167 | 0.127 | 0 |
| CTHRC1 | CTHRC1 | Q96CG8 | Collagen triple helix repeat-containing protein 1 | chr8 | GO:1905114 | Not Cancer Driver | No | 31 | 0.128 | 62 | 5 | 0.081 | 0 |
| CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:1905114 | Census, Compendium | Yes | 415 | 0.531 | 288 | 301 | 1.045 | 14 |
| DAAM1 | DAAM1 | Q9Y4D1 | Disheveled-associated activator of morphogenesis 1 | chr14 | GO:1905114 | Not Cancer Driver | No | 152 | 0.141 | 391 | 47 | 0.12 | 0 |
| DKK1 | DKK1 | O94907 | Dickkopf-related protein 1 | chr10 | GO:1905114 | Not Cancer Driver | No | 58 | 0.218 | 47 | 8 | 0.17 | 0 |
| DVL1 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | GO:1905114 | Not Cancer Driver | No | 73 | 0.105 | 434 | 38 | 0.088 | 0 |
| DVL2 | DVL2 | O14641 | Segment polarity protein dishevelled homolog DVL-2 | chr17 | GO:1905114 | Not Cancer Driver | No | 96 | 0.13 | 514 | 64 | 0.125 | 0 |
| DVL3 | DVL3 | Q92997 | Segment polarity protein dishevelled homolog DVL-3 | chr3 | GO:1905114 | Not Cancer Driver | No | 97 | 0.135 | 437 | 58 | 0.133 | 0 |
| EXT1 | EXT1 | Q16394 | Exostosin-1 | chr8 | GO:1905114 | Census | Yes | 107 | 0.143 | 58 | 7 | 0.121 | 12 |
| FZD1 | FZD1 | Q9UP38 | Frizzled-1 | chr7 | GO:1905114 | Not Cancer Driver | No | 78 | 0.121 | 133 | 2 | 0.015 | 0 |
| FZD10 | FZD10 | Q9ULW2 | Frizzled-10 | chr12 | GO:1905114 | Not Cancer Driver | No | 148 | 0.255 | 65 | 15 | 0.231 | 0 |
| FZD2 | FZD2 | Q14332 | Frizzled-2 | chr17 | GO:1905114 | Not Cancer Driver | No | 85 | 0.15 | 47 | 5 | 0.106 | 1 |
| FZD3_ENST00000240093 | FZD3 | Q9NPG1 | Frizzled-3 | chr8 | GO:1905114 | Not Cancer Driver | No | 64 | 0.096 | 141 | 13 | 0.092 | 0 |
| FZD4 | FZD4 | Q9ULV1 | Frizzled-4 | chr11 | GO:1905114 | Not Cancer Driver | No | 57 | 0.106 | 33 | 5 | 0.152 | 19 |
| FZD6 | FZD6 | O60353 | Frizzled-6 | chr8 | GO:1905114 | Not Cancer Driver | No | 95 | 0.135 | 172 | 15 | 0.087 | 1 |
| FZD7 | FZD7 | O75084 | Frizzled-7 | chr2 | GO:1905114 | Not Cancer Driver | No | 90 | 0.157 | 22 | 2 | 0.091 | 0 |
| GATA3_ENST00000346208 | GATA3 | P23771 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | GO:1905114 | Census, Compendium | Yes | 111 | 0.251 | 364 | 87 | 0.239 | 2 |
| GLI1 | GLI1 | P08151 | Zinc finger protein GLI1 | chr12 | GO:1905114 | Census, Compendium | Yes | 206 | 0.186 | 1015 | 184 | 0.181 | 0 |
| GPC4 | GPC4 | O75487 | Glypican-4 | chrX | GO:1905114 | Not Cancer Driver | No | 88 | 0.158 | 122 | 16 | 0.131 | 0 |
| GPC6 | GPC6 | Q9Y625 | Glypican-6 | chr13 | GO:1905114 | Not Cancer Driver | No | 133 | 0.24 | 140 | 36 | 0.257 | 0 |
| GRHL3 | GRHL3 | Q8TE85 | Grainyhead-like protein 3 homolog | chr1 | GO:1905114 | Not Cancer Driver | No | 83 | 0.133 | 291 | 38 | 0.131 | 3 |
| ITGAM_ENST00000287497 | ITGAM | P11215 | Integrin alpha-M | chr16 | GO:1905114 | Not Cancer Driver | No | 191 | 0.166 | 133 | 12 | 0.09 | 0 |
| LGR4 | LGR4 | Q9BXB1 | Leucine-rich repeat-containing G-protein coupled receptor 4 | chr11 | GO:1905114 | Not Cancer Driver | No | 108 | 0.114 | 16 | 3 | 0.188 | 0 |
| LRP5 | LRP5 | O75197 | Low-density lipoprotein receptor-related protein 5 | chr11 | GO:1905114 | Not Cancer Driver | No | 253 | 0.157 | 188 | 28 | 0.149 | 55 |
| LRP6 | LRP6 | O75581 | Low-density lipoprotein receptor-related protein 6 | chr12 | GO:1905114 | Not Cancer Driver | No | 206 | 0.128 | 255 | 30 | 0.118 | 5 |
| MAGI2 | MAGI2 | Q86UL8 | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 | chr7 | GO:1905114 | Not Cancer Driver | No | 305 | 0.21 | 1086 | 201 | 0.185 | 0 |
| MED12 | MED12 | Q93074 | Mediator of RNA polymerase II transcription subunit 12 | chrX | GO:1905114 | Census, Compendium | Yes | 409 | 0.188 | 974 | 175 | 0.18 | 5 |
| MITF_ENST00000448226 | MITF | O75030 | Microphthalmia-associated transcription factor | chr3 | GO:1905114 | Census | Yes | 80 | 0.152 | 408 | 69 | 0.169 | 7 |
| MYOC | MYOC | Q99972 | Myocilin | chr1 | GO:1905114 | Not Cancer Driver | No | 92 | 0.183 | 196 | 43 | 0.219 | 58 |
| NDP_ENST00000642620 | NDP | Q00604 | Norrin | chrX | GO:1905114 | Not Cancer Driver | No | 14 | 0.105 | 0 | 0 | 0.0 | 60 |
| NLK | NLK | Q9UBE8 | Serine/threonine-protein kinase NLK | chr17 | GO:1905114 | Not Cancer Driver | No | 54 | 0.102 | 152 | 20 | 0.132 | 0 |
| P2RX7 | P2RX7 | Q99572 | P2X purinoceptor 7 | chr12 | GO:1905114 | Not Cancer Driver | No | 51 | 0.086 | 14 | 2 | 0.143 | 0 |
| PLPP3 | PLPP3 | O14495 | Phospholipid phosphatase 3 | chr1 | GO:1905114 | Not Cancer Driver | No | 48 | 0.154 | 10 | 1 | 0.1 | 0 |
| PRICKLE1_ENST00000640055 | PRICKLE1 | Q96MT3 | Prickle-like protein 1 | chr12 | GO:1905114 | Not Cancer Driver | No | 146 | 0.176 | 485 | 91 | 0.188 | 3 |
| PRICKLE2 | PRICKLE2 | Q7Z3G6 | Prickle-like protein 2 | chr3 | GO:1905114 | Not Cancer Driver | No | 131 | 0.155 | 502 | 80 | 0.159 | 0 |
| PTK7_ENST00000230419 | PTK7 | Q13308 | Inactive tyrosine-protein kinase 7 | chr6 | GO:1905114 | Not Cancer Driver | No | 153 | 0.143 | 359 | 58 | 0.162 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | GO:1905114 | Census, Compendium | Yes | 66 | 0.344 | 2 | 1 | 0.5 | 6 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:1905114 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
| ROR1 | ROR1 | Q01973 | Inactive tyrosine-protein kinase transmembrane receptor ROR1 | chr1 | GO:1905114 | Not Cancer Driver | No | 144 | 0.154 | 280 | 43 | 0.154 | 1 |
| ROR2 | ROR2 | Q01974 | Tyrosine-protein kinase transmembrane receptor ROR2 | chr9 | GO:1905114 | Not Cancer Driver | No | 203 | 0.215 | 299 | 71 | 0.237 | 5 |
| RYK_ENST00000623711 | RYK | P34925 | Tyrosine-protein kinase RYK | chr3 | GO:1905114 | Not Cancer Driver | No | 55 | 0.091 | 85 | 4 | 0.047 | 0 |
| SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:1905114 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
| SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:1905114 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
| SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:1905114 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
| SMO | SMO | Q99835 | Smoothened homolog | chr7 | GO:1905114 | Census, Compendium | Yes | 112 | 0.142 | 241 | 27 | 0.112 | 1 |
| SMURF1 | SMURF1 | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 | chr7 | GO:1905114 | Not Cancer Driver | No | 89 | 0.118 | 256 | 31 | 0.121 | 0 |
| SMURF2 | SMURF2 | Q9HAU4 | E3 ubiquitin-protein ligase SMURF2 | chr17 | GO:1905114 | Not Cancer Driver | No | 87 | 0.116 | 242 | 28 | 0.116 | 0 |
| TCF7L2_ENST00000355995 | TCF7L2 | Q9NQB0 | Transcription factor 7-like 2 | chr10 | GO:1905114 | Census, Compendium | Yes | 122 | 0.197 | 516 | 93 | 0.18 | 0 |
| TIAM1 | TIAM1 | Q13009 | Rho guanine nucleotide exchange factor TIAM1 | chr21 | GO:1905114 | Not Cancer Driver | No | 370 | 0.233 | 810 | 194 | 0.24 | 0 |
| VANGL1 | VANGL1 | Q8TAA9 | Vang-like protein 1 | chr1 | GO:1905114 | Not Cancer Driver | No | 72 | 0.137 | 140 | 15 | 0.107 | 3 |
| VANGL2 | VANGL2 | Q9ULK5 | Vang-like protein 2 | chr1 | GO:1905114 | Not Cancer Driver | No | 122 | 0.234 | 150 | 37 | 0.247 | 3 |
| WNT1 | WNT1 | P04628 | Proto-oncogene Wnt-1 | chr12 | GO:1905114 | Not Cancer Driver | No | 29 | 0.078 | 25 | 0 | 0.0 | 8 |
| WNT11 | WNT11 | O96014 | Protein Wnt-11 | chr11 | GO:1905114 | Not Cancer Driver | No | 55 | 0.155 | 59 | 4 | 0.068 | 0 |
| WNT2 | WNT2 | P09544 | Protein Wnt-2 | chr7 | GO:1905114 | Not Cancer Driver | No | 85 | 0.236 | 11 | 3 | 0.273 | 0 |
| WNT3 | WNT3 | P56703 | Proto-oncogene Wnt-3 | chr17 | GO:1905114 | Not Cancer Driver | No | 56 | 0.158 | 34 | 7 | 0.206 | 0 |
| WNT3A | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:1905114 | Not Cancer Driver | No | 77 | 0.219 | 37 | 5 | 0.135 | 0 |
| WNT4 | WNT4 | P56705 | Protein Wnt-4 | chr1 | GO:1905114 | Not Cancer Driver | No | 30 | 0.085 | 39 | 4 | 0.103 | 4 |
| WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:1905114 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
| WNT7A | WNT7A | O00755 | Protein Wnt-7a | chr3 | GO:1905114 | Not Cancer Driver | No | 93 | 0.266 | 18 | 9 | 0.5 | 4 |
| WNT8A_ENST00000398754 | WNT8A | Q9H1J5 | Protein Wnt-8a | chr5 | GO:1905114 | Not Cancer Driver | No | 50 | 0.142 | 3 | 0 | 0.0 | 0 |
| WNT9B | WNT9B | O14905 | Protein Wnt-9b | chr17 | GO:1905114 | Not Cancer Driver | No | 47 | 0.132 | 11 | 4 | 0.364 | 0 |