Total number of protein in "GO:1904356" GO term: 57
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACD_ENST00000620761 | ACD | Q96AP0 | Adrenocortical dysplasia protein homolog | chr16 | GO:1904356 | Not Cancer Driver | No | 49 | 0.107 | 256 | 34 | 0.133 | 1 |
ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:1904356 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
ATR | ATR | Q13535 | Serine/threonine-protein kinase ATR | chr3 | GO:1904356 | Census, Compendium | Yes | 338 | 0.128 | 106 | 14 | 0.132 | 1 |
AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | GO:1904356 | Not Cancer Driver | No | 51 | 0.148 | 63 | 8 | 0.127 | 0 |
CCT2 | CCT2 | P78371 | T-complex protein 1 subunit beta | chr12 | GO:1904356 | Not Cancer Driver | No | 63 | 0.118 | 46 | 3 | 0.065 | 0 |
CCT3 | CCT3 | P49368 | T-complex protein 1 subunit gamma | chr1 | GO:1904356 | Not Cancer Driver | No | 71 | 0.13 | 95 | 12 | 0.126 | 0 |
CCT4 | CCT4 | P50991 | T-complex protein 1 subunit delta | chr2 | GO:1904356 | Not Cancer Driver | No | 51 | 0.095 | 92 | 2 | 0.022 | 0 |
CCT5 | CCT5 | P48643 | T-complex protein 1 subunit epsilon | chr5 | GO:1904356 | Not Cancer Driver | No | 83 | 0.153 | 72 | 10 | 0.139 | 1 |
CCT6A | CCT6A | P40227 | T-complex protein 1 subunit zeta | chr7 | GO:1904356 | Not Cancer Driver | No | 66 | 0.124 | 5 | 1 | 0.2 | 0 |
CCT7 | CCT7 | Q99832 | T-complex protein 1 subunit eta | chr2 | GO:1904356 | Not Cancer Driver | No | 59 | 0.109 | 36 | 6 | 0.167 | 0 |
CCT8 | CCT8 | P50990 | T-complex protein 1 subunit theta | chr21 | GO:1904356 | Not Cancer Driver | No | 41 | 0.075 | 36 | 2 | 0.056 | 0 |
CTC1 | CTC1 | Q2NKJ3 | CST complex subunit CTC1 | chr17 | GO:1904356 | Not Cancer Driver | No | 142 | 0.117 | 103 | 8 | 0.078 | 9 |
CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:1904356 | Census, Compendium | Yes | 415 | 0.531 | 288 | 301 | 1.045 | 14 |
DCP2 | DCP2 | Q8IU60 | m7GpppN-mRNA hydrolase | chr5 | GO:1904356 | Not Cancer Driver | No | 57 | 0.136 | 167 | 24 | 0.144 | 0 |
DHX36 | DHX36 | Q9H2U1 | ATP-dependent DNA/RNA helicase DHX36 | chr3 | GO:1904356 | Not Cancer Driver | No | 159 | 0.158 | 222 | 39 | 0.176 | 0 |
DKC1 | DKC1 | O60832 | H/ACA ribonucleoprotein complex subunit DKC1 | chrX | GO:1904356 | Not Cancer Driver | No | 62 | 0.121 | 145 | 29 | 0.2 | 24 |
ERCC4 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:1904356 | Census | Yes | 120 | 0.131 | 225 | 27 | 0.12 | 15 |
EXOSC10 | EXOSC10 | Q01780 | Exosome component 10 | chr1 | GO:1904356 | Not Cancer Driver | No | 87 | 0.098 | 375 | 35 | 0.093 | 0 |
FBXO4 | FBXO4 | Q9UKT5 | F-box only protein 4 | chr5 | GO:1904356 | Not Cancer Driver | No | 55 | 0.142 | 68 | 7 | 0.103 | 0 |
GNL3L_ENST00000360845 | GNL3L | Q9NVN8 | Guanine nucleotide-binding protein-like 3-like protein | chrX | GO:1904356 | Not Cancer Driver | No | 120 | 0.206 | 242 | 43 | 0.178 | 0 |
HMBOX1_ENST00000397358 | HMBOX1 | Q6NT76 | Homeobox-containing protein 1 | chr8 | GO:1904356 | Not Cancer Driver | No | 55 | 0.131 | 319 | 41 | 0.129 | 0 |
HNRNPA1 | HNRNPA1 | P09651 | Heterogeneous nuclear ribonucleoprotein A1 | chr12 | GO:1904356 | Not Cancer Driver | No | 70 | 0.188 | 290 | 58 | 0.2 | 4 |
HNRNPA2B1 | HNRNPA2B1 | P22626 | Heterogeneous nuclear ribonucleoproteins A2/B1 | chr7 | GO:1904356 | Census, Compendium | Yes | 68 | 0.193 | 255 | 41 | 0.161 | 0 |
HNRNPC_ENST00000420743 | HNRNPC | P07910 | Heterogeneous nuclear ribonucleoproteins C1/C2 | chr14 | GO:1904356 | Not Cancer Driver | No | 42 | 0.137 | 227 | 35 | 0.154 | 0 |
HNRNPU | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | GO:1904356 | Not Cancer Driver | No | 77 | 0.093 | 504 | 45 | 0.089 | 0 |
MAP2K7_ENST00000397979 | MAP2K7 | O14733 | Dual specificity mitogen-activated protein kinase kinase 7 | chr19 | GO:1904356 | Compendium | Yes | 89 | 0.212 | 144 | 20 | 0.139 | 0 |
MAP3K4 | MAP3K4 | Q9Y6R4 | Mitogen-activated protein kinase kinase kinase 4 | chr6 | GO:1904356 | Not Cancer Driver | No | 261 | 0.162 | 520 | 86 | 0.165 | 0 |
MAPK15 | MAPK15 | Q8TD08 | Mitogen-activated protein kinase 15 | chr8 | GO:1904356 | Not Cancer Driver | No | 81 | 0.149 | 235 | 37 | 0.157 | 0 |
MAPK1_ENST00000398822 | MAPK1 | P28482 | Mitogen-activated protein kinase 1 | chr22 | GO:1904356 | Census, Compendium | Yes | 62 | 0.172 | 2 | 0 | 0.0 | 7 |
MAPK3 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | GO:1904356 | Not Cancer Driver | No | 38 | 0.1 | 49 | 5 | 0.102 | 0 |
MAPKAPK5 | MAPKAPK5 | Q8IW41 | MAP kinase-activated protein kinase 5 | chr12 | GO:1904356 | Not Cancer Driver | No | 51 | 0.108 | 101 | 12 | 0.119 | 0 |
NAF1 | NAF1 | Q96HR8 | H/ACA ribonucleoprotein complex non-core subunit NAF1 | chr4 | GO:1904356 | Not Cancer Driver | No | 61 | 0.123 | 386 | 44 | 0.114 | 0 |
NAT10 | NAT10 | Q9H0A0 | RNA cytidine acetyltransferase | chr11 | GO:1904356 | Not Cancer Driver | No | 109 | 0.106 | 142 | 18 | 0.127 | 0 |
NEK2 | NEK2 | P51955 | Serine/threonine-protein kinase Nek2 | chr1 | GO:1904356 | Not Cancer Driver | No | 61 | 0.137 | 92 | 19 | 0.207 | 0 |
NEK7 | NEK7 | Q8TDX7 | Serine/threonine-protein kinase Nek7 | chr1 | GO:1904356 | Not Cancer Driver | No | 35 | 0.116 | 23 | 0 | 0.0 | 0 |
PARN | PARN | O95453 | Poly(A)-specific ribonuclease PARN | chr16 | GO:1904356 | Not Cancer Driver | No | 71 | 0.111 | 197 | 22 | 0.112 | 2 |
PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:1904356 | Not Cancer Driver | No | 119 | 0.117 | 320 | 34 | 0.106 | 0 |
PIF1_ENST00000559239 | PIF1 | Q9H611 | ATP-dependent DNA helicase PIF1 | chr15 | GO:1904356 | Not Cancer Driver | No | 54 | 0.084 | 209 | 11 | 0.053 | 0 |
PINX1 | PINX1 | Q96BK5 | PIN2/TERF1-interacting telomerase inhibitor 1 | chr8 | GO:1904356 | Not Cancer Driver | No | 66 | 0.201 | 328 | 66 | 0.201 | 0 |
PKIB_ENST00000368448 | PKIB | Q9C010 | cAMP-dependent protein kinase inhibitor beta | chr6 | GO:1904356 | Not Cancer Driver | No | 13 | 0.167 | 78 | 13 | 0.167 | 0 |
PNKP | PNKP | Q96T60 | Bifunctional polynucleotide phosphatase/kinase | chr19 | GO:1904356 | Not Cancer Driver | No | 53 | 0.102 | 177 | 23 | 0.13 | 4 |
POT1 | POT1 | Q9NUX5 | Protection of telomeres protein 1 | chr7 | GO:1904356 | Census, Compendium | Yes | 113 | 0.178 | 31 | 6 | 0.194 | 9 |
PRKCQ | PRKCQ | Q04759 | Protein kinase C theta type | chr10 | GO:1904356 | Not Cancer Driver | No | 147 | 0.208 | 28 | 9 | 0.321 | 0 |
RTEL1_ENST00000370018 | RTEL1 | Q9NZ71 | Regulator of telomere elongation helicase 1 | chr20 | GO:1904356 | Not Cancer Driver | No | 144 | 0.118 | 474 | 64 | 0.135 | 14 |
SLX1B | SLX1B | Q9BQ83 | Structure-specific endonuclease subunit SLX1 | chr16 | GO:1904356 | Not Cancer Driver | No | 3 | 0.011 | 80 | 1 | 0.013 | 0 |
SLX4 | SLX4 | Q8IY92 | Structure-specific endonuclease subunit SLX4 | chr16 | GO:1904356 | Not Cancer Driver | No | 271 | 0.148 | 1573 | 232 | 0.147 | 0 |
SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:1904356 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
STN1 | STN1 | Q9H668 | CST complex subunit STN1 | chr10 | GO:1904356 | Not Cancer Driver | No | 41 | 0.111 | 27 | 2 | 0.074 | 2 |
TCP1 | TCP1 | P17987 | T-complex protein 1 subunit alpha | chr6 | GO:1904356 | Not Cancer Driver | No | 54 | 0.097 | 55 | 10 | 0.182 | 0 |
TEN1 | TEN1 | Q86WV5 | CST complex subunit TEN1 | chr17 | GO:1904356 | Not Cancer Driver | No | 6 | 0.049 | 8 | 4 | 0.5 | 0 |
TERF1 | TERF1 | P54274 | Telomeric repeat-binding factor 1 | chr8 | GO:1904356 | Not Cancer Driver | No | 63 | 0.144 | 220 | 34 | 0.155 | 0 |
TERF2 | TERF2 | Q15554 | Telomeric repeat-binding factor 2 | chr16 | GO:1904356 | Not Cancer Driver | No | 33 | 0.061 | 361 | 20 | 0.055 | 0 |
TINF2 | TINF2 | Q9BSI4 | TERF1-interacting nuclear factor 2 | chr14 | GO:1904356 | Not Cancer Driver | No | 38 | 0.084 | 190 | 17 | 0.089 | 4 |
TNKS | TNKS | O95271 | Poly [ADP-ribose] polymerase tankyrase-1 | chr8 | GO:1904356 | Not Cancer Driver | No | 163 | 0.123 | 480 | 59 | 0.123 | 0 |
TNKS2 | TNKS2 | Q9H2K2 | Poly [ADP-ribose] polymerase tankyrase-2 | chr10 | GO:1904356 | Not Cancer Driver | No | 117 | 0.1 | 255 | 24 | 0.094 | 0 |
XRCC5_ENST00000392132 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | GO:1904356 | Not Cancer Driver | No | 87 | 0.119 | 118 | 11 | 0.093 | 0 |
XRN1 | XRN1 | Q8IZH2 | 5'-3' exoribonuclease 1 | chr3 | GO:1904356 | Not Cancer Driver | No | 213 | 0.125 | 577 | 65 | 0.113 | 0 |