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Total number of protein in "GO:1904029" GO term:  61

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:1904029 Not Cancer Driver No 80 0.097 182 17 0.093 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:1904029 Census, Compendium Yes 108 0.225 158 24 0.152 4
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:1904029 Census, Compendium Yes 412 0.145 2406 345 0.143 22
CASP3 CASP3 P42574 Caspase-3 chr4 GO:1904029 Census Yes 32 0.116 62 5 0.081 0
CCNB1 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 GO:1904029 Not Cancer Driver No 49 0.113 145 14 0.097 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:1904029 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCND2 CCND2 P30279 G1/S-specific cyclin-D2 chr12 GO:1904029 Census, Compendium Yes 39 0.135 29 7 0.241 5
CCND3 CCND3 P30281 G1/S-specific cyclin-D3 chr6 GO:1904029 Census, Compendium Yes 29 0.099 46 8 0.174 0
CCNK CCNK O75909 Cyclin-K chr14 GO:1904029 Not Cancer Driver No 39 0.067 347 15 0.043 1
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 GO:1904029 Not Cancer Driver No 85 0.117 495 61 0.123 0
CCNT2 CCNT2 O60583 Cyclin-T2 chr2 GO:1904029 Not Cancer Driver No 76 0.104 471 52 0.11 0
CCNY CCNY Q8ND76 Cyclin-Y chr10 GO:1904029 Not Cancer Driver No 38 0.111 94 6 0.064 0
CCNYL1 CCNYL1 Q8N7R7 Cyclin-Y-like protein 1 chr2 GO:1904029 Not Cancer Driver No 31 0.086 100 8 0.08 0
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:1904029 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:1904029 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5R2 CDK5R2 Q13319 Cyclin-dependent kinase 5 activator 2 chr2 GO:1904029 Not Cancer Driver No 14 0.038 204 5 0.025 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 GO:1904029 Not Cancer Driver No 73 0.121 95 12 0.126 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 GO:1904029 Not Cancer Driver No 217 0.115 1136 128 0.113 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:1904029 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:1904029 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDKN1C CDKN1C P49918 Cyclin-dependent kinase inhibitor 1C chr11 GO:1904029 Not Cancer Driver No 2 0.006 256 1 0.004 7
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 GO:1904029 Census, Compendium Yes 166 1.064 83 88 1.06 36
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:1904029 Not Cancer Driver No 15 0.109 67 3 0.045 0
CDKN2C_ENST00000371761 CDKN2C P42773 Cyclin-dependent kinase 4 inhibitor C chr1 GO:1904029 Census, Compendium Yes 23 0.137 49 6 0.122 0
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 GO:1904029 Not Cancer Driver No 17 0.102 44 3 0.068 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:1904029 Census, Compendium Yes 12 0.034 342 12 0.035 1
CKS1B CKS1B P61024 Cyclin-dependent kinases regulatory subunit 1 chr1 GO:1904029 Not Cancer Driver No 10 0.127 10 0 0.0 0
CKS2 CKS2 P33552 Cyclin-dependent kinases regulatory subunit 2 chr9 GO:1904029 Not Cancer Driver No 9 0.114 10 2 0.2 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:1904029 Census, Compendium Yes 444 0.367 223 35 0.157 1
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:1904029 Not Cancer Driver No 75 0.144 243 38 0.156 1
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 GO:1904029 Not Cancer Driver No 40 0.111 352 40 0.114 0
HEXIM2_ENST00000592695 HEXIM2 Q96MH2 Protein HEXIM2 chr17 GO:1904029 Not Cancer Driver No 35 0.122 286 35 0.122 0
HHEX HHEX Q03014 Hematopoietically-expressed homeobox protein HHEX chr10 GO:1904029 Not Cancer Driver No 23 0.085 193 21 0.109 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:1904029 Census, Compendium Yes 100 0.138 254 43 0.169 0
INCA1_ENST00000576820 INCA1 Q0VD86 Protein INCA1 chr17 GO:1904029 Not Cancer Driver No 18 0.076 195 14 0.072 0
IPO5_ENST00000490680 IPO5 O00410 Importin-5 chr13 GO:1904029 Not Cancer Driver No 128 0.117 52 3 0.058 0
IPO7 IPO7 O95373 Importin-7 chr11 GO:1904029 Not Cancer Driver No 138 0.133 202 30 0.149 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 GO:1904029 Not Cancer Driver No 107 0.129 266 27 0.102 0
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 GO:1904029 Census, Compendium Yes 161 0.142 788 100 0.127 0
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 GO:1904029 Census, Compendium Yes 178 0.164 687 116 0.169 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 GO:1904029 Not Cancer Driver No 37 0.132 120 16 0.133 0
MEN1 MEN1 O00255 Menin chr11 GO:1904029 Census, Compendium Yes 73 0.119 228 15 0.066 90
MNAT1 MNAT1 P51948 CDK-activating kinase assembly factor MAT1 chr14 GO:1904029 Not Cancer Driver No 23 0.074 64 2 0.031 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:1904029 Not Cancer Driver No 284 0.303 853 263 0.308 0
NR2F2 NR2F2 P24468 COUP transcription factor 2 chr15 GO:1904029 Not Cancer Driver No 66 0.159 101 1 0.01 5
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:1904029 Census Yes 37 0.154 99 22 0.222 2
PKD1 PKD1 P98161 Polycystin-1 chr16 GO:1904029 Not Cancer Driver No 393 0.091 690 66 0.096 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:1904029 Not Cancer Driver No 113 0.117 375 35 0.093 10
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:1904029 Not Cancer Driver No 87 0.144 119 13 0.109 0
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:1904029 Not Cancer Driver No 182 0.247 537 141 0.263 0
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:1904029 Not Cancer Driver No 20 0.088 53 5 0.094 0
PSRC1_ENST00000409138 PSRC1 Q6PGN9 Proline/serine-rich coiled-coil protein 1 chr1 GO:1904029 Not Cancer Driver No 30 0.083 361 30 0.083 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:1904029 Census, Compendium Yes 505 1.253 76 4 0.053 41
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:1904029 Not Cancer Driver No 9 0.066 81 7 0.086 0
SPDYA_ENST00000379579 SPDYA Q5MJ70 Speedy protein A chr2 GO:1904029 Not Cancer Driver No 39 0.125 119 11 0.092 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:1904029 Census Yes 53 0.099 130 11 0.085 1
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 GO:1904029 Not Cancer Driver No 121 0.122 659 83 0.126 2
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:1904029 Compendium Yes 61 0.18 285 52 0.182 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:1904029 Census, Compendium Yes 98 0.124 231 33 0.143 1
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:1904029 Not Cancer Driver No 193 0.146 1045 154 0.147 0
WEE2 WEE2 P0C1S8 Wee1-like protein kinase 2 chr7 GO:1904029 Not Cancer Driver No 104 0.183 345 65 0.188 1