Total number of protein in "GO:1903507" GO term: 88
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ATRX | ATRX | P46100 | Transcriptional regulator ATRX | chrX | GO:1903507 | Census, Compendium | Yes | 487 | 0.195 | 1672 | 301 | 0.18 | 33 |
| AXIN1 | AXIN1 | O15169 | Axin-1 | chr16 | GO:1903507 | Census, Compendium | Yes | 120 | 0.139 | 619 | 88 | 0.142 | 4 |
| BAG3 | BAG3 | O95817 | BAG family molecular chaperone regulator 3 | chr10 | GO:1903507 | Not Cancer Driver | No | 57 | 0.099 | 571 | 57 | 0.1 | 7 |
| BHLHE41 | BHLHE41 | Q9C0J9 | Class E basic helix-loop-helix protein 41 | chr12 | GO:1903507 | Not Cancer Driver | No | 21 | 0.044 | 213 | 10 | 0.047 | 0 |
| BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:1903507 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
| CC2D1A | CC2D1A | Q6P1N0 | Coiled-coil and C2 domain-containing protein 1A | chr19 | GO:1903507 | Not Cancer Driver | No | 146 | 0.154 | 718 | 100 | 0.139 | 0 |
| CITED2_ENST00000367651 | CITED2 | Q99967 | Cbp/p300-interacting transactivator 2 | chr6 | GO:1903507 | Not Cancer Driver | No | 23 | 0.085 | 230 | 18 | 0.078 | 0 |
| COPS2_ENST00000388901 | COPS2 | P61201 | COP9 signalosome complex subunit 2 | chr15 | GO:1903507 | Not Cancer Driver | No | 59 | 0.133 | 59 | 9 | 0.153 | 0 |
| CREB1_ENST00000430624 | CREB1 | P16220 | Cyclic AMP-responsive element-binding protein 1 | chr2 | GO:1903507 | Census | Yes | 25 | 0.076 | 277 | 23 | 0.083 | 0 |
| CTNNBIP1_ENST00000377258 | CTNNBIP1 | Q9NSA3 | Beta-catenin-interacting protein 1 | chr1 | GO:1903507 | Not Cancer Driver | No | 8 | 0.099 | 64 | 7 | 0.109 | 0 |
| DACH1_ENST00000619232 | DACH1 | Q9UI36 | Dachshund homolog 1 | chr13 | GO:1903507 | Not Cancer Driver | No | 157 | 0.207 | 641 | 134 | 0.209 | 0 |
| DEDD_ENST00000545495 | DEDD | O75618 | Death effector domain-containing protein | chr1 | GO:1903507 | Not Cancer Driver | No | 36 | 0.113 | 90 | 7 | 0.078 | 0 |
| DNAJB1 | DNAJB1 | P25685 | DnaJ homolog subfamily B member 1 | chr19 | GO:1903507 | Census, Compendium | Yes | 35 | 0.103 | 196 | 26 | 0.133 | 0 |
| E2F1 | E2F1 | Q01094 | Transcription factor E2F1 | chr20 | GO:1903507 | Not Cancer Driver | No | 49 | 0.112 | 272 | 23 | 0.085 | 0 |
| E2F7 | E2F7 | Q96AV8 | Transcription factor E2F7 | chr12 | GO:1903507 | Not Cancer Driver | No | 122 | 0.134 | 554 | 70 | 0.126 | 0 |
| EAPP | EAPP | Q56P03 | E2F-associated phosphoprotein | chr14 | GO:1903507 | Not Cancer Driver | No | 35 | 0.123 | 210 | 27 | 0.129 | 0 |
| EIF4A2 | EIF4A2 | Q14240 | Eukaryotic initiation factor 4A-II | chr3 | GO:1903507 | Census | Yes | 77 | 0.189 | 27 | 14 | 0.519 | 0 |
| EZH2_ENST00000460911 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | GO:1903507 | Census, Compendium | Yes | 120 | 0.161 | 284 | 44 | 0.155 | 11 |
| FLNA | FLNA | P21333 | Filamin-A | chrX | GO:1903507 | Census | Yes | 416 | 0.157 | 1456 | 214 | 0.147 | 28 |
| GATA6 | GATA6 | Q92908 | Transcription factor GATA-6 | chr18 | GO:1903507 | Not Cancer Driver | No | 57 | 0.096 | 476 | 51 | 0.107 | 10 |
| H2AFY | MACROH2A1 | O75367 | Core histone macro-H2A.1 | chr5 | GO:1903507 | Not Cancer Driver | No | 46 | 0.124 | 125 | 19 | 0.152 | 0 |
| H2AFY2 | MACROH2A2 | Q9P0M6 | Core histone macro-H2A.2 | chr10 | GO:1903507 | Not Cancer Driver | No | 59 | 0.159 | 171 | 32 | 0.187 | 0 |
| HEXIM1 | HEXIM1 | O94992 | Protein HEXIM1 | chr17 | GO:1903507 | Not Cancer Driver | No | 40 | 0.111 | 352 | 40 | 0.114 | 0 |
| HEY1_ENST00000354724 | HEY1 | Q9Y5J3 | Hairy/enhancer-of-split related with YRPW motif protein 1 | chr8 | GO:1903507 | Census | Yes | 33 | 0.109 | 172 | 15 | 0.087 | 0 |
| HEY2 | HEY2 | Q9UBP5 | Hairy/enhancer-of-split related with YRPW motif protein 2 | chr6 | GO:1903507 | Not Cancer Driver | No | 64 | 0.19 | 179 | 26 | 0.145 | 0 |
| HHEX | HHEX | Q03014 | Hematopoietically-expressed homeobox protein HHEX | chr10 | GO:1903507 | Not Cancer Driver | No | 23 | 0.085 | 193 | 21 | 0.109 | 0 |
| HIF1AN | HIF1AN | Q9NWT6 | Hypoxia-inducible factor 1-alpha inhibitor | chr10 | GO:1903507 | Not Cancer Driver | No | 37 | 0.106 | 77 | 9 | 0.117 | 0 |
| HMGB1_ENST00000405805 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:1903507 | Not Cancer Driver | No | 25 | 0.116 | 203 | 20 | 0.099 | 0 |
| HNRNPU | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | GO:1903507 | Not Cancer Driver | No | 77 | 0.093 | 504 | 45 | 0.089 | 0 |
| HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | GO:1903507 | Not Cancer Driver | No | 24 | 0.037 | 200 | 13 | 0.065 | 0 |
| ID1 | ID1 | P41134 | DNA-binding protein inhibitor ID-1 | chr20 | GO:1903507 | Not Cancer Driver | No | 20 | 0.129 | 17 | 6 | 0.353 | 0 |
| IMPACT | IMPACT | Q9P2X3 | Protein IMPACT | chr18 | GO:1903507 | Not Cancer Driver | No | 49 | 0.153 | 84 | 12 | 0.143 | 0 |
| JUN | JUN | P05412 | Transcription factor Jun | chr1 | GO:1903507 | Census | Yes | 35 | 0.106 | 281 | 25 | 0.089 | 0 |
| KDM2A | KDM2A | Q9Y2K7 | Lysine-specific demethylase 2A | chr11 | GO:1903507 | Not Cancer Driver | No | 131 | 0.113 | 387 | 48 | 0.124 | 0 |
| LARP7_ENST00000344442 | LARP7 | Q4G0J3 | La-related protein 7 | chr4 | GO:1903507 | Not Cancer Driver | No | 58 | 0.1 | 350 | 44 | 0.126 | 0 |
| LILRB4 | LILRB4 | Q8NHJ6 | Leukocyte immunoglobulin-like receptor subfamily B member 4 | chr19 | GO:1903507 | Not Cancer Driver | No | 162 | 0.362 | 277 | 115 | 0.415 | 0 |
| MAD2L2 | MAD2L2 | Q9UI95 | Mitotic spindle assembly checkpoint protein MAD2B | chr1 | GO:1903507 | Not Cancer Driver | No | 22 | 0.104 | 0 | 0 | 0.0 | 1 |
| MAF1_ENST00000532522 | MAF1 | Q9H063 | Repressor of RNA polymerase III transcription MAF1 homolog | chr8 | GO:1903507 | Not Cancer Driver | No | 22 | 0.086 | 74 | 4 | 0.054 | 0 |
| MECP2_ENST00000303391 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | GO:1903507 | Not Cancer Driver | No | 75 | 0.154 | 483 | 74 | 0.153 | 46 |
| MORC1 | MORC1 | Q86VD1 | MORC family CW-type zinc finger protein 1 | chr3 | GO:1903507 | Not Cancer Driver | No | 300 | 0.305 | 252 | 77 | 0.306 | 0 |
| MUC1_ENST00000611571 | MUC1 | P15941 | Mucin-1 | chr1 | GO:1903507 | Census | Yes | 40 | 0.032 | 1050 | 19 | 0.018 | 0 |
| NAB2 | NAB2 | Q15742 | NGFI-A-binding protein 2 | chr12 | GO:1903507 | Census | Yes | 67 | 0.128 | 395 | 51 | 0.129 | 0 |
| NACC2_ENST00000371753 | NACC2 | Q96BF6 | Nucleus accumbens-associated protein 2 | chr9 | GO:1903507 | Not Cancer Driver | No | 24 | 0.041 | 238 | 10 | 0.042 | 0 |
| NCK1_ENST00000288986 | NCK1 | P16333 | Cytoplasmic protein NCK1 | chr3 | GO:1903507 | Not Cancer Driver | No | 48 | 0.127 | 111 | 17 | 0.153 | 0 |
| NCK2_ENST00000393349 | NCK2 | O43639 | Cytoplasmic protein NCK2 | chr2 | GO:1903507 | Not Cancer Driver | No | 89 | 0.234 | 88 | 19 | 0.216 | 0 |
| NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | GO:1903507 | Not Cancer Driver | No | 150 | 0.114 | 711 | 79 | 0.111 | 0 |
| NELFA_ENST00000411638 | NELFA | Q9H3P2 | Negative elongation factor A | chr4 | GO:1903507 | Not Cancer Driver | No | 68 | 0.129 | 373 | 58 | 0.155 | 0 |
| NELFCD | NELFCD | Q8IXH7 | Negative elongation factor C/D | chr20 | GO:1903507 | Not Cancer Driver | No | 69 | 0.117 | 53 | 1 | 0.019 | 0 |
| NELFE | NELFE | P18615 | Negative elongation factor E | chr6 | GO:1903507 | Not Cancer Driver | No | 47 | 0.124 | 352 | 45 | 0.128 | 0 |
| NFATC3 | NFATC3 | Q12968 | Nuclear factor of activated T-cells, cytoplasmic 3 | chr16 | GO:1903507 | Not Cancer Driver | No | 112 | 0.104 | 730 | 80 | 0.11 | 0 |
| NFATC4_ENST00000250373 | NFATC4 | Q14934 | Nuclear factor of activated T-cells, cytoplasmic 4 | chr14 | GO:1903507 | Not Cancer Driver | No | 155 | 0.172 | 685 | 120 | 0.175 | 0 |
| NFIB_ENST00000380959 | NFIB | O00712 | Nuclear factor 1 B-type | chr9 | GO:1903507 | Census | Yes | 63 | 0.15 | 254 | 36 | 0.142 | 3 |
| NIF3L1_ENST00000409357 | NIF3L1 | Q9GZT8 | NIF3-like protein 1 | chr2 | GO:1903507 | Not Cancer Driver | No | 55 | 0.146 | 43 | 3 | 0.07 | 0 |
| NOP53 | NOP53 | Q9NZM5 | Ribosome biogenesis protein NOP53 | chr19 | GO:1903507 | Not Cancer Driver | No | 59 | 0.123 | 391 | 41 | 0.105 | 0 |
| PDGFB | PDGFB | P01127 | Platelet-derived growth factor subunit B | chr22 | GO:1903507 | Census | Yes | 37 | 0.154 | 99 | 22 | 0.222 | 2 |
| PHB_ENST00000300408 | PHB1 | P35232 | Prohibitin 1 | chr17 | GO:1903507 | Not Cancer Driver | No | 37 | 0.136 | 4 | 1 | 0.25 | 0 |
| POU5F1 | POU5F1 | Q01860 | POU domain, class 5, transcription factor 1 | chr6 | GO:1903507 | Census | Yes | 36 | 0.1 | 186 | 12 | 0.065 | 0 |
| PPARA_ENST00000402126 | PPARA | Q07869 | Peroxisome proliferator-activated receptor alpha | chr22 | GO:1903507 | Not Cancer Driver | No | 63 | 0.135 | 68 | 9 | 0.132 | 0 |
| PPARD_ENST00000360694 | PPARD | Q03181 | Peroxisome proliferator-activated receptor delta | chr6 | GO:1903507 | Not Cancer Driver | No | 72 | 0.163 | 69 | 7 | 0.101 | 0 |
| PPARG | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:1903507 | Census | Yes | 72 | 0.143 | 44 | 4 | 0.091 | 3 |
| PRDX5 | PRDX5 | P30044 | Peroxiredoxin-5, mitochondrial | chr11 | GO:1903507 | Not Cancer Driver | No | 22 | 0.103 | 0 | 0 | 0.0 | 0 |
| RARA | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:1903507 | Census, Compendium | Yes | 70 | 0.152 | 167 | 14 | 0.084 | 0 |
| RB1 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | GO:1903507 | Census, Compendium | Yes | 140 | 0.151 | 282 | 32 | 0.113 | 22 |
| RECQL5 | RECQL5 | O94762 | ATP-dependent DNA helicase Q5 | chr17 | GO:1903507 | Not Cancer Driver | No | 132 | 0.133 | 495 | 71 | 0.143 | 0 |
| RELA | RELA | Q04206 | Transcription factor p65 | chr11 | GO:1903507 | Compendium | Yes | 75 | 0.136 | 400 | 48 | 0.12 | 0 |
| REST | REST | Q13127 | RE1-silencing transcription factor | chr4 | GO:1903507 | Not Cancer Driver | No | 142 | 0.129 | 868 | 113 | 0.13 | 4 |
| RNF168 | RNF168 | Q8IYW5 | E3 ubiquitin-protein ligase RNF168 | chr3 | GO:1903507 | Not Cancer Driver | No | 77 | 0.135 | 471 | 66 | 0.14 | 0 |
| RNF8 | RNF8 | O76064 | E3 ubiquitin-protein ligase RNF8 | chr6 | GO:1903507 | Not Cancer Driver | No | 56 | 0.115 | 226 | 29 | 0.128 | 0 |
| SCAF4 | SCAF4 | O95104 | SR-related and CTD-associated factor 4 | chr21 | GO:1903507 | Not Cancer Driver | No | 162 | 0.141 | 938 | 132 | 0.141 | 0 |
| SCAF8_ENST00000367178 | SCAF8 | Q9UPN6 | SR-related and CTD-associated factor 8 | chr6 | GO:1903507 | Not Cancer Driver | No | 155 | 0.122 | 939 | 118 | 0.126 | 0 |
| SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:1903507 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
| SIRT2 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:1903507 | Not Cancer Driver | No | 56 | 0.144 | 85 | 17 | 0.2 | 0 |
| SMAD7 | SMAD7 | O15105 | Mothers against decapentaplegic homolog 7 | chr18 | GO:1903507 | Not Cancer Driver | No | 40 | 0.094 | 139 | 0 | 0.0 | 0 |
| SOX9 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:1903507 | Compendium | Yes | 86 | 0.169 | 495 | 82 | 0.166 | 18 |
| SRF | SRF | P11831 | Serum response factor | chr6 | GO:1903507 | Not Cancer Driver | No | 44 | 0.087 | 443 | 42 | 0.095 | 0 |
| SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | GO:1903507 | Not Cancer Driver | No | 10 | 0.099 | 76 | 7 | 0.092 | 0 |
| SUPT4H1_ENST00000580947 | SUPT4H1 | P63272 | Transcription elongation factor SPT4 | chr17 | GO:1903507 | Not Cancer Driver | No | 15 | 0.128 | 0 | 0 | 0.0 | 0 |
| SUPT5H | SUPT5H | O00267 | Transcription elongation factor SPT5 | chr19 | GO:1903507 | Not Cancer Driver | No | 165 | 0.152 | 572 | 87 | 0.152 | 0 |
| TCERG1 | TCERG1 | O14776 | Transcription elongation regulator 1 | chr5 | GO:1903507 | Not Cancer Driver | No | 143 | 0.13 | 811 | 110 | 0.136 | 0 |
| TFAP2A | TFAP2A | P05549 | Transcription factor AP-2-alpha | chr6 | GO:1903507 | Not Cancer Driver | No | 77 | 0.176 | 275 | 44 | 0.16 | 4 |
| TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:1903507 | Not Cancer Driver | No | 41 | 0.105 | 41 | 4 | 0.098 | 10 |
| THRA | THRA | P10827 | Thyroid hormone receptor alpha | chr17 | GO:1903507 | Not Cancer Driver | No | 69 | 0.141 | 207 | 30 | 0.145 | 2 |
| TMBIM6_ENST00000549385 | TMBIM6 | P55061 | Bax inhibitor 1 | chr12 | GO:1903507 | Not Cancer Driver | No | 16 | 0.068 | 3 | 0 | 0.0 | 0 |
| VHL | VHL | P40337 | von Hippel-Lindau disease tumor suppressor | chr3 | GO:1903507 | Census, Compendium | Yes | 142 | 0.667 | 117 | 36 | 0.308 | 133 |
| YY1 | YY1 | P25490 | Transcriptional repressor protein YY1 | chr14 | GO:1903507 | Not Cancer Driver | No | 37 | 0.089 | 336 | 26 | 0.077 | 2 |
| ZNF451 | ZNF451 | Q9Y4E5 | E3 SUMO-protein ligase ZNF451 | chr6 | GO:1903507 | Not Cancer Driver | No | 169 | 0.159 | 191 | 25 | 0.131 | 0 |
| ZNF512B | ZNF512B | Q96KM6 | Zinc finger protein 512B | chr20 | GO:1903507 | Not Cancer Driver | No | 101 | 0.113 | 694 | 83 | 0.12 | 0 |
| ZNF653 | ZNF653 | Q96CK0 | Zinc finger protein 653 | chr19 | GO:1903507 | Not Cancer Driver | No | 78 | 0.127 | 371 | 45 | 0.121 | 0 |