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Total number of protein in "GO:1903047" GO term:  135

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ANKLE2 ANKLE2 Q86XL3 Ankyrin repeat and LEM domain-containing protein 2 chr12 GO:1903047 Not Cancer Driver No 127 0.135 521 71 0.136 2
ARF1_ENST00000272102 ARF1 P84077 ADP-ribosylation factor 1 chr1 GO:1903047 Not Cancer Driver No 30 0.166 4 2 0.5 2
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:1903047 Census, Compendium Yes 469 0.153 225 39 0.173 41
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 GO:1903047 Not Cancer Driver No 36 0.089 178 21 0.118 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:1903047 Not Cancer Driver No 51 0.148 63 8 0.127 0
AURKC AURKC Q9UQB9 Aurora kinase C chr19 GO:1903047 Not Cancer Driver No 70 0.227 43 5 0.116 0
BACH1_ENST00000286800 BACH1 O14867 Transcription regulator protein BACH1 chr21 GO:1903047 Not Cancer Driver No 105 0.143 328 39 0.119 0
BANF1_ENST00000445560 BANF1 O75531 Barrier-to-autointegration factor chr11 GO:1903047 Not Cancer Driver No 10 0.112 11 2 0.182 1
BOD1 BOD1 Q96IK1 Biorientation of chromosomes in cell division protein 1 chr5 GO:1903047 Not Cancer Driver No 16 0.086 133 10 0.075 0
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:1903047 Census, Compendium Yes 457 0.134 1542 225 0.146 46
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 GO:1903047 Census, Compendium Yes 193 0.142 1182 172 0.146 0
CASP2 CASP2 P42575 Caspase-2 chr7 GO:1903047 Not Cancer Driver No 63 0.139 42 12 0.286 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:1903047 Census, Compendium Yes 55 0.186 31 25 0.806 0
CDC45_ENST00000407835 CDC45 O75419 Cell division control protein 45 homolog chr22 GO:1903047 Not Cancer Driver No 73 0.129 66 16 0.242 5
CDK14 CDK14 O94921 Cyclin-dependent kinase 14 chr7 GO:1903047 Not Cancer Driver No 93 0.198 154 21 0.136 0
CDK15 CDK15 Q96Q40 Cyclin-dependent kinase 15 chr2 GO:1903047 Not Cancer Driver No 66 0.152 35 4 0.114 0
CDK16_ENST00000357227 CDK16 Q00536 Cyclin-dependent kinase 16 chrX GO:1903047 Not Cancer Driver No 55 0.111 139 30 0.216 0
CDK17 CDK17 Q00537 Cyclin-dependent kinase 17 chr12 GO:1903047 Not Cancer Driver No 76 0.145 198 26 0.131 0
CDK18_ENST00000360066 CDK18 Q07002 Cyclin-dependent kinase 18 chr1 GO:1903047 Not Cancer Driver No 64 0.135 132 17 0.129 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:1903047 Not Cancer Driver No 24 0.081 0 0 0.0 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:1903047 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:1903047 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:1903047 Census, Compendium Yes 19 0.096 198 19 0.096 0
CENPE CENPE Q02224 Centromere-associated protein E chr4 GO:1903047 Not Cancer Driver No 343 0.127 1620 228 0.141 2
CEP55 CEP55 Q53EZ4 Centrosomal protein of 55 kDa chr10 GO:1903047 Not Cancer Driver No 59 0.127 264 26 0.098 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:1903047 Census, Compendium Yes 335 0.617 157 130 0.828 13
CHMP1A CHMP1A Q9HD42 Charged multivesicular body protein 1a chr16 GO:1903047 Not Cancer Driver No 18 0.092 110 6 0.055 0
CHMP1B CHMP1B Q7LBR1 Charged multivesicular body protein 1b chr18 GO:1903047 Not Cancer Driver No 23 0.116 133 16 0.12 0
CHMP2A_ENST00000601220 CHMP2A O43633 Charged multivesicular body protein 2a chr19 GO:1903047 Not Cancer Driver No 29 0.131 161 22 0.137 0
CHMP2B CHMP2B Q9UQN3 Charged multivesicular body protein 2b chr3 GO:1903047 Not Cancer Driver No 28 0.131 183 25 0.137 4
CHMP3 CHMP3 Q9Y3E7 Charged multivesicular body protein 3 chr2 GO:1903047 Not Cancer Driver No 25 0.113 137 13 0.095 0
CHMP4A_ENST00000609024 CHMP4A Q9BY43 Charged multivesicular body protein 4a chr14 GO:1903047 Not Cancer Driver No 24 0.108 204 23 0.113 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 GO:1903047 Not Cancer Driver No 25 0.112 201 22 0.109 2
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 GO:1903047 Not Cancer Driver No 33 0.142 224 31 0.138 0
CHMP5 CHMP5 Q9NZZ3 Charged multivesicular body protein 5 chr9 GO:1903047 Not Cancer Driver No 24 0.11 195 18 0.092 0
CHMP6 CHMP6 Q96FZ7 Charged multivesicular body protein 6 chr17 GO:1903047 Not Cancer Driver No 26 0.129 88 16 0.182 0
CHMP7_ENST00000313219 CHMP7 Q8WUX9 Charged multivesicular body protein 7 chr8 GO:1903047 Not Cancer Driver No 50 0.11 140 15 0.107 0
CLASP1_ENST00000646274 CLASP1 Q7Z460 CLIP-associating protein 1 chr2 GO:1903047 Not Cancer Driver No 163 0.106 642 70 0.109 0
CLASP2 CLASP2 O75122 CLIP-associating protein 2 chr3 GO:1903047 Not Cancer Driver No 158 0.122 676 94 0.139 0
CNTROB_ENST00000563694 CNTROB Q8N137 Centrobin chr17 GO:1903047 Not Cancer Driver No 97 0.107 837 93 0.111 0
CRADD_ENST00000332896 CRADD P78560 Death domain-containing protein CRADD chr12 GO:1903047 Not Cancer Driver No 35 0.176 45 5 0.111 1
CTDNEP1_ENST00000318988 CTDNEP1 O95476 CTD nuclear envelope phosphatase 1 chr17 GO:1903047 Not Cancer Driver No 20 0.082 0 0 0.0 0
CTDP1 CTDP1 Q9Y5B0 RNA polymerase II subunit A C-terminal domain phosphatase chr18 GO:1903047 Not Cancer Driver No 121 0.126 624 87 0.139 0
DLGAP5 DLGAP5 Q15398 Disks large-associated protein 5 chr14 GO:1903047 Not Cancer Driver No 84 0.099 676 70 0.104 0
DNA2 DNA2 P51530 DNA replication ATP-dependent helicase/nuclease DNA2 chr10 GO:1903047 Not Cancer Driver No 120 0.113 52 8 0.154 3
DSCC1 DSCC1 Q9BVC3 Sister chromatid cohesion protein DCC1 chr8 GO:1903047 Not Cancer Driver No 28 0.071 41 4 0.098 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:1903047 Not Cancer Driver No 49 0.112 272 23 0.085 0
E2F4 E2F4 Q16254 Transcription factor E2F4 chr16 GO:1903047 Not Cancer Driver No 44 0.107 242 32 0.132 0
E2F6 E2F6 O75461 Transcription factor E2F6 chr2 GO:1903047 Not Cancer Driver No 20 0.071 105 10 0.095 0
E2F7 E2F7 Q96AV8 Transcription factor E2F7 chr12 GO:1903047 Not Cancer Driver No 122 0.134 554 70 0.126 0
EPS8_ENST00000645775 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 GO:1903047 Not Cancer Driver No 106 0.129 459 54 0.118 0
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 GO:1903047 Not Cancer Driver No 90 0.208 35 7 0.2 4
FBXO31 FBXO31 Q5XUX0 F-box only protein 31 chr16 GO:1903047 Not Cancer Driver No 72 0.134 231 30 0.13 0
GFI1 GFI1 Q99684 Zinc finger protein Gfi-1 chr1 GO:1903047 Not Cancer Driver No 57 0.135 199 29 0.146 2
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:1903047 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GINS1 GINS1 Q14691 DNA replication complex GINS protein PSF1 chr20 GO:1903047 Not Cancer Driver No 21 0.107 18 3 0.167 2
GINS3_ENST00000318129 GINS3 Q9BRX5 DNA replication complex GINS protein PSF3 chr16 GO:1903047 Not Cancer Driver No 36 0.167 14 0 0.0 0
GML GML Q99445 Glycosyl-phosphatidylinositol-anchored molecule-like protein chr8 GO:1903047 Not Cancer Driver No 49 0.31 12 6 0.5 0
GTSE1 GTSE1 Q9NYZ3 G2 and S phase-expressed protein 1 chr22 GO:1903047 Not Cancer Driver No 91 0.126 660 85 0.129 0
HINFP HINFP Q9BQA5 Histone H4 transcription factor chr11 GO:1903047 Not Cancer Driver No 65 0.126 154 24 0.156 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:1903047 Not Cancer Driver No 14 0.104 52 7 0.135 0
KATNB1 KATNB1 Q9BVA0 Katanin p80 WD40 repeat-containing subunit B1 chr16 GO:1903047 Not Cancer Driver No 70 0.107 179 24 0.134 3
KIF11 KIF11 P52732 Kinesin-like protein KIF11 chr10 GO:1903047 Not Cancer Driver No 90 0.085 389 26 0.067 4
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 GO:1903047 Not Cancer Driver No 79 0.089 340 40 0.118 1
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 GO:1903047 Not Cancer Driver No 102 0.106 559 62 0.111 0
KIF3B KIF3B O15066 Kinesin-like protein KIF3B chr20 GO:1903047 Not Cancer Driver No 105 0.141 485 69 0.142 2
KIF4A KIF4A O95239 Chromosome-associated kinesin KIF4A chrX GO:1903047 Not Cancer Driver No 188 0.153 674 116 0.172 0
KIF4B KIF4B Q2VIQ3 Chromosome-associated kinesin KIF4B chr5 GO:1903047 Not Cancer Driver No 303 0.246 571 150 0.263 0
KLF11 KLF11 O14901 Krueppel-like factor 11 chr2 GO:1903047 Not Cancer Driver No 57 0.111 308 38 0.123 2
KLHDC8B KLHDC8B Q8IXV7 Kelch domain-containing protein 8B chr3 GO:1903047 Not Cancer Driver No 37 0.105 16 0 0.0 0
KPNB1 KPNB1 Q14974 Importin subunit beta-1 chr17 GO:1903047 Not Cancer Driver No 92 0.105 94 11 0.117 0
LIG1 LIG1 P18858 DNA ligase 1 chr19 GO:1903047 Not Cancer Driver No 137 0.149 397 62 0.156 0
LPIN1_ENST00000256720 LPIN1 Q14693 Phosphatidate phosphatase LPIN1 chr2 GO:1903047 Not Cancer Driver No 120 0.135 447 70 0.157 0
MAU2 MAU2 Q9Y6X3 MAU2 chromatid cohesion factor homolog chr19 GO:1903047 Not Cancer Driver No 68 0.111 36 1 0.028 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 GO:1903047 Not Cancer Driver No 104 0.115 275 38 0.138 1
MCM3_ENST00000229854 MCM3 P25205 DNA replication licensing factor MCM3 chr6 GO:1903047 Not Cancer Driver No 92 0.114 310 47 0.152 0
MCM4 MCM4 P33991 DNA replication licensing factor MCM4 chr8 GO:1903047 Not Cancer Driver No 121 0.14 215 35 0.163 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:1903047 Census, Compendium Yes 56 0.114 297 37 0.125 0
MITD1 MITD1 Q8WV92 MIT domain-containing protein 1 chr2 GO:1903047 Not Cancer Driver No 31 0.124 45 8 0.178 0
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:1903047 Census Yes 40 0.032 1050 19 0.018 0
NAA50 NAA50 Q9GZZ1 N-alpha-acetyltransferase 50 chr3 GO:1903047 Not Cancer Driver No 14 0.083 14 1 0.071 0
NDE1_ENST00000396354 NDE1 Q9NXR1 Nuclear distribution protein nudE homolog 1 chr16 GO:1903047 Not Cancer Driver No 45 0.134 316 42 0.133 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:1903047 Not Cancer Driver No 32 0.093 202 16 0.079 0
NEK6_ENST00000545174 NEK6 Q9HC98 Serine/threonine-protein kinase Nek6 chr9 GO:1903047 Not Cancer Driver No 31 0.099 36 0 0.0 0
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:1903047 Compendium Yes 353 0.126 1528 184 0.12 37
NPAT NPAT Q14207 Protein NPAT chr11 GO:1903047 Not Cancer Driver No 134 0.094 1149 113 0.098 0
NUP62 NUP62 P37198 Nuclear pore glycoprotein p62 chr19 GO:1903047 Not Cancer Driver No 76 0.146 377 56 0.149 1
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:1903047 Not Cancer Driver No 30 0.115 22 3 0.136 1
PDCD6IP_ENST00000307296 PDCD6IP Q8WUM4 Programmed cell death 6-interacting protein chr3 GO:1903047 Not Cancer Driver No 85 0.098 272 22 0.081 0
PIDD1 PIDD1 Q9HB75 p53-induced death domain-containing protein 1 chr11 GO:1903047 Not Cancer Driver No 93 0.102 137 14 0.102 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:1903047 Not Cancer Driver No 87 0.144 119 13 0.109 0
PLK2 PLK2 Q9NYY3 Serine/threonine-protein kinase PLK2 chr5 GO:1903047 Not Cancer Driver No 92 0.134 178 21 0.118 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:1903047 Not Cancer Driver No 75 0.116 202 15 0.074 0
PLK5 PLK5 Q496M5 Inactive serine/threonine-protein kinase PLK5 chr19 GO:1903047 Not Cancer Driver No 8 0.024 215 4 0.019 0
PML PML P29590 Protein PML chr15 GO:1903047 Census, Compendium Yes 112 0.127 312 34 0.109 0
POLA1_ENST00000379059 POLA1 P09884 DNA polymerase alpha catalytic subunit chrX GO:1903047 Not Cancer Driver No 185 0.127 347 45 0.13 3
PPP2R2D PPP2R2D Q66LE6 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform chr10 GO:1903047 Not Cancer Driver No 50 0.11 65 9 0.138 0
PRAP1 PRAP1 Q96NZ9 Proline-rich acidic protein 1 chr10 GO:1903047 Not Cancer Driver No 14 0.093 124 13 0.105 0
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 GO:1903047 Not Cancer Driver No 63 0.102 235 26 0.111 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:1903047 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:1903047 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:1903047 Not Cancer Driver No 538 0.13 421 61 0.145 2
RACGAP1_ENST00000454520 RACGAP1 Q9H0H5 Rac GTPase-activating protein 1 chr12 GO:1903047 Not Cancer Driver No 74 0.117 255 27 0.106 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:1903047 Not Cancer Driver No 42 0.124 47 5 0.106 3
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:1903047 Census, Compendium Yes 140 0.151 282 32 0.113 22
RCC1_ENST00000373833 RCC1 P18754 Regulator of chromosome condensation chr1 GO:1903047 Not Cancer Driver No 54 0.128 143 15 0.105 0
REEP3 REEP3 Q6NUK4 Receptor expression-enhancing protein 3 chr10 GO:1903047 Not Cancer Driver No 15 0.059 94 5 0.053 0
REEP4 REEP4 Q9H6H4 Receptor expression-enhancing protein 4 chr8 GO:1903047 Not Cancer Driver No 27 0.105 90 15 0.167 0
RFWD3 RFWD3 Q6PCD5 E3 ubiquitin-protein ligase RFWD3 chr16 GO:1903047 Census Yes 68 0.088 318 30 0.094 1
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:1903047 Census, Compendium Yes 99 0.513 46 13 0.283 2
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 GO:1903047 Not Cancer Driver No 28 0.104 114 16 0.14 0
RPL24 RPL24 P83731 60S ribosomal protein L24 chr3 GO:1903047 Not Cancer Driver No 19 0.121 105 14 0.133 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:1903047 Not Cancer Driver No 16 0.11 114 13 0.114 0
RPS27L RPS27L Q71UM5 40S ribosomal protein S27-like chr15 GO:1903047 Not Cancer Driver No 4 0.048 22 2 0.091 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:1903047 Not Cancer Driver No 144 0.118 474 64 0.135 14
RTF2_ENST00000357348 RTF2 Q9BY42 Replication termination factor 2 chr20 GO:1903047 Not Cancer Driver No 44 0.144 170 22 0.129 0
SDE2 SDE2 Q6IQ49 Replication stress response regulator SDE2 chr1 GO:1903047 Not Cancer Driver No 56 0.124 290 35 0.121 0
SGO1 SGO1 Q5FBB7 Shugoshin 1 chr3 GO:1903047 Not Cancer Driver No 57 0.102 360 39 0.108 1
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:1903047 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:1903047 Not Cancer Driver No 48 0.12 163 15 0.092 0
SPAST SPAST Q9UBP0 Spastin chr2 GO:1903047 Not Cancer Driver No 73 0.119 270 25 0.093 77
TFDP1 TFDP1 Q14186 Transcription factor Dp-1 chr13 GO:1903047 Not Cancer Driver No 82 0.2 245 47 0.192 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:1903047 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:1903047 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIAP1 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 GO:1903047 Not Cancer Driver No 9 0.118 20 1 0.05 0
UBE2C UBE2C O00762 Ubiquitin-conjugating enzyme E2 C chr20 GO:1903047 Not Cancer Driver No 13 0.073 40 0 0.0 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 GO:1903047 Not Cancer Driver No 16 0.101 16 3 0.188 0
UBE2S UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 GO:1903047 Not Cancer Driver No 25 0.113 102 12 0.118 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:1903047 Not Cancer Driver No 88 0.109 186 16 0.086 16
VPS4A VPS4A Q9UN37 Vacuolar protein sorting-associated protein 4A chr16 GO:1903047 Not Cancer Driver No 48 0.11 167 17 0.102 4
VPS4B VPS4B O75351 Vacuolar protein sorting-associated protein 4B chr18 GO:1903047 Not Cancer Driver No 52 0.117 195 22 0.113 0
VRK1 VRK1 Q99986 Serine/threonine-protein kinase VRK1 chr14 GO:1903047 Not Cancer Driver No 52 0.131 80 9 0.113 0
WAC WAC Q9BTA9 WW domain-containing adapter protein with coiled-coil chr10 GO:1903047 Not Cancer Driver No 106 0.164 571 95 0.166 0
ZFYVE19 ZFYVE19 Q96K21 Abscission/NoCut checkpoint regulator chr15 GO:1903047 Not Cancer Driver No 41 0.087 361 28 0.078 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:1903047 Not Cancer Driver No 38 0.083 291 27 0.093 0