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Total number of protein in "GO:1903046" GO term:  122

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:1903046 Not Cancer Driver No 51 0.129 6 2 0.333 0
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 GO:1903046 Not Cancer Driver No 32 0.077 16 2 0.125 0
AGO4 AGO4 Q9HCK5 Protein argonaute-4 chr1 GO:1903046 Not Cancer Driver No 100 0.116 183 24 0.131 0
ANKRD31 ANKRD31 Q8N7Z5 Ankyrin repeat domain-containing protein 31 chr5 GO:1903046 Not Cancer Driver No 62 0.033 1144 34 0.03 0
ASPM ASPM Q8IZT6 Abnormal spindle-like microcephaly-associated protein chr1 GO:1903046 Not Cancer Driver No 554 0.159 424 67 0.158 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:1903046 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:1903046 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 GO:1903046 Not Cancer Driver No 36 0.089 178 21 0.118 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:1903046 Not Cancer Driver No 98 0.087 861 79 0.092 0
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:1903046 Census, Compendium Yes 457 0.134 1542 225 0.146 46
BRDT_ENST00000362005 BRDT Q58F21 Bromodomain testis-specific protein chr1 GO:1903046 Not Cancer Driver No 173 0.183 703 121 0.172 0
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:1903046 Census Yes 174 0.139 397 59 0.149 6
BTBD18 BTBD18 B2RXH4 BTB/POZ domain-containing protein 18 chr11 GO:1903046 Not Cancer Driver No 29 0.041 567 25 0.044 0
BUB1 BUB1 O43683 Mitotic checkpoint serine/threonine-protein kinase BUB1 chr2 GO:1903046 Not Cancer Driver No 139 0.128 466 64 0.137 0
BUB1B BUB1B O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta chr15 GO:1903046 Census Yes 96 0.091 480 35 0.073 7
C14orf39 SIX6OS1 Q8N1H7 Protein SIX6OS1 chr14 GO:1903046 Not Cancer Driver No 128 0.218 326 76 0.233 0
C19orf57_ENST00000586783 BRME1 Q0VDD7 Break repair meiotic recombinase recruitment factor 1 chr19 GO:1903046 Not Cancer Driver No 91 0.136 632 88 0.139 0
C1orf146 SPO16 Q5VVC0 Protein SPO16 homolog chr1 GO:1903046 Not Cancer Driver No 24 0.133 0 0 0.0 0
CCDC155 KASH5 Q8N6L0 Protein KASH5 chr19 GO:1903046 Not Cancer Driver No 88 0.157 401 70 0.175 0
CCNA1 CCNA1 P78396 Cyclin-A1 chr13 GO:1903046 Not Cancer Driver No 112 0.241 82 21 0.256 0
CCNB1IP1 CCNB1IP1 Q9NPC3 E3 ubiquitin-protein ligase CCNB1IP1 chr14 GO:1903046 Census Yes 43 0.155 68 13 0.191 0
CCNB2 CCNB2 O95067 G2/mitotic-specific cyclin-B2 chr15 GO:1903046 Not Cancer Driver No 33 0.083 103 10 0.097 0
CDC25B CDC25B P30305 M-phase inducer phosphatase 2 chr20 GO:1903046 Not Cancer Driver No 80 0.138 328 43 0.131 0
CENPC CENPC Q03188 Centromere protein C chr4 GO:1903046 Not Cancer Driver No 96 0.102 790 84 0.106 0
CHFR CHFR Q96EP1 E3 ubiquitin-protein ligase CHFR chr12 GO:1903046 Not Cancer Driver No 85 0.128 341 54 0.158 0
DDX4 DDX4 Q9NQI0 Probable ATP-dependent RNA helicase DDX4 chr5 GO:1903046 Not Cancer Driver No 115 0.159 315 49 0.156 0
DMC1 DMC1 Q14565 Meiotic recombination protein DMC1/LIM15 homolog chr22 GO:1903046 Not Cancer Driver No 39 0.115 49 5 0.102 0
DMRTC2 DMRTC2 Q8IXT2 Doublesex- and mab-3-related transcription factor C2 chr19 GO:1903046 Not Cancer Driver No 45 0.123 310 35 0.113 0
DNMT3L_ENST00000628202 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 GO:1903046 Not Cancer Driver No 83 0.215 10 1 0.1 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:1903046 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:1903046 Not Cancer Driver No 62 0.145 21 6 0.286 2
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 GO:1903046 Not Cancer Driver No 142 0.117 585 71 0.121 0
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:1903046 Not Cancer Driver No 42 0.141 105 14 0.133 1
EREG EREG O14944 Proepiregulin chr4 GO:1903046 Not Cancer Driver No 26 0.154 10 3 0.3 0
ESPL1 ESPL1 Q14674 Separin chr12 GO:1903046 Not Cancer Driver No 211 0.1 380 39 0.103 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 GO:1903046 Census, Compendium Yes 176 0.121 181 14 0.077 3
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 GO:1903046 Not Cancer Driver No 48 0.107 113 13 0.115 0
FMN2 FMN2 Q9NZ56 Formin-2 chr1 GO:1903046 Not Cancer Driver No 614 0.357 1322 475 0.359 0
FOXJ2 FOXJ2 Q9P0K8 Forkhead box protein J2 chr12 GO:1903046 Not Cancer Driver No 81 0.141 483 65 0.135 0
FOXJ3 FOXJ3 Q9UPW0 Forkhead box protein J3 chr1 GO:1903046 Not Cancer Driver No 77 0.124 459 54 0.118 0
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 GO:1903046 Not Cancer Driver No 115 0.115 854 96 0.112 0
HORMAD1 HORMAD1 Q86X24 HORMA domain-containing protein 1 chr1 GO:1903046 Not Cancer Driver No 76 0.193 178 31 0.174 0
HORMAD2 HORMAD2 Q8N7B1 HORMA domain-containing protein 2 chr22 GO:1903046 Not Cancer Driver No 28 0.091 29 3 0.103 0
HSF2BP HSF2BP O75031 Heat shock factor 2-binding protein chr21 GO:1903046 Not Cancer Driver No 52 0.156 23 3 0.13 1
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 GO:1903046 Not Cancer Driver No 93 0.146 286 38 0.133 0
HUS1 HUS1 O60921 Checkpoint protein HUS1 chr7 GO:1903046 Not Cancer Driver No 25 0.089 17 2 0.118 0
HUS1B HUS1B Q8NHY5 Checkpoint protein HUS1B chr6 GO:1903046 Not Cancer Driver No 50 0.18 10 1 0.1 0
INCENP INCENP Q9NQS7 Inner centromere protein chr11 GO:1903046 Not Cancer Driver No 107 0.117 856 103 0.12 0
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 GO:1903046 Not Cancer Driver No 33 0.118 169 26 0.154 0
M1AP M1AP Q8TC57 Meiosis 1 arrest protein chr2 GO:1903046 Not Cancer Driver No 81 0.153 157 27 0.172 0
MAJIN_ENST00000530444 MAJIN Q3KP22 Membrane-anchored junction protein chr11 GO:1903046 Not Cancer Driver No 17 0.097 143 15 0.105 0
MARF1 MARF1 Q9Y4F3 Meiosis regulator and mRNA stability factor 1 chr16 GO:1903046 Not Cancer Driver No 199 0.114 524 73 0.139 0
MASTL MASTL Q96GX5 Serine/threonine-protein kinase greatwall chr10 GO:1903046 Not Cancer Driver No 90 0.102 389 44 0.113 0
MEIKIN MEIKIN A0A087WXM9 Meiosis-specific kinetochore protein chr5 GO:1903046 Not Cancer Driver No 2 0.005 221 1 0.005 0
MEIOB_ENST00000397344 MEIOB Q8N635 Meiosis-specific with OB domain-containing protein chr16 GO:1903046 Not Cancer Driver No 37 0.084 21 2 0.095 1
MEIOC MEIOC A2RUB1 Meiosis-specific coiled-coil domain-containing protein MEIOC chr17 GO:1903046 Not Cancer Driver No 92 0.097 529 54 0.102 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:1903046 Census Yes 92 0.122 208 22 0.106 85
MLH3_ENST00000556740 MLH3 Q9UHC1 DNA mismatch repair protein Mlh3 chr14 GO:1903046 Not Cancer Driver No 154 0.106 593 60 0.101 9
MOS MOS P00540 Proto-oncogene serine/threonine-protein kinase mos chr8 GO:1903046 Not Cancer Driver No 94 0.272 16 4 0.25 0
MOV10L1_ENST00000545383 MOV10L1 Q9BXT6 RNA helicase Mov10l1 chr22 GO:1903046 Not Cancer Driver No 184 0.152 178 21 0.118 0
MSH5_ENST00000375755 MSH5 O43196 MutS protein homolog 5 chr6 GO:1903046 Not Cancer Driver No 101 0.121 86 4 0.047 1
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:1903046 Census Yes 154 0.113 386 41 0.106 6
MYBL1 MYBL1 P10243 Myb-related protein A chr8 GO:1903046 Not Cancer Driver No 78 0.104 501 58 0.116 0
MYH9 MYH9 P35579 Myosin-9 chr22 GO:1903046 Census, Compendium Yes 310 0.158 1120 160 0.143 17
NCAPD2 NCAPD2 Q15021 Condensin complex subunit 1 chr12 GO:1903046 Not Cancer Driver No 124 0.089 345 35 0.101 0
NCAPD3 NCAPD3 P42695 Condensin-2 complex subunit D3 chr11 GO:1903046 Not Cancer Driver No 193 0.129 304 42 0.138 1
NCAPH NCAPH Q15003 Condensin complex subunit 2 chr2 GO:1903046 Not Cancer Driver No 97 0.131 465 60 0.129 1
NCAPH2_ENST00000420993 NCAPH2 Q6IBW4 Condensin-2 complex subunit H2 chr22 GO:1903046 Not Cancer Driver No 67 0.111 335 39 0.116 0
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 GO:1903046 Not Cancer Driver No 80 0.125 313 45 0.144 0
NSUN2 NSUN2 Q08J23 RNA cytosine C(5)-methyltransferase NSUN2 chr5 GO:1903046 Not Cancer Driver No 112 0.146 221 21 0.095 1
P3H4_ENST00000393928 P3H4 Q92791 Endoplasmic reticulum protein SC65 chr17 GO:1903046 Not Cancer Driver No 46 0.105 82 9 0.11 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:1903046 Not Cancer Driver No 87 0.144 119 13 0.109 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:1903046 Census, Compendium Yes 179 0.304 0 0 0.0 4
PRDM9 PRDM9 Q9NQV7 Histone-lysine N-methyltransferase PRDM9 chr5 GO:1903046 Not Cancer Driver No 494 0.553 372 201 0.54 0
PSMC3IP PSMC3IP Q9P2W1 Homologous-pairing protein 2 homolog chr17 GO:1903046 Not Cancer Driver No 25 0.115 73 8 0.11 0
RAD1 RAD1 O60671 Cell cycle checkpoint protein RAD1 chr5 GO:1903046 Not Cancer Driver No 29 0.103 4 1 0.25 0
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 GO:1903046 Census, Compendium Yes 115 0.182 421 74 0.176 3
RAD21L1 RAD21L1 Q9H4I0 Double-strand-break repair protein rad21-like protein 1 chr20 GO:1903046 Not Cancer Driver No 37 0.067 186 5 0.027 0
RAD51C RAD51C O43502 DNA repair protein RAD51 homolog 3 chr17 GO:1903046 Not Cancer Driver No 47 0.125 18 2 0.111 6
REC8_ENST00000611366 REC8 O95072 Meiotic recombination protein REC8 homolog chr14 GO:1903046 Not Cancer Driver No 60 0.11 244 26 0.107 0
RNF212 RNF212 Q495C1 Probable E3 SUMO-protein ligase RNF212 chr4 GO:1903046 Not Cancer Driver No 36 0.121 58 12 0.207 0
SGO1 SGO1 Q5FBB7 Shugoshin 1 chr3 GO:1903046 Not Cancer Driver No 57 0.102 360 39 0.108 1
SGO2 SGO2 Q562F6 Shugoshin 2 chr2 GO:1903046 Not Cancer Driver No 164 0.13 1025 134 0.131 0
SHCBP1L SHCBP1L Q9BZQ2 Testicular spindle-associated protein SHCBP1L chr1 GO:1903046 Not Cancer Driver No 95 0.145 150 14 0.093 0
SLC25A31 SLC25A31 Q9H0C2 ADP/ATP translocase 4 chr4 GO:1903046 Not Cancer Driver No 68 0.216 8 0 0.0 0
SLC2A8 SLC2A8 Q9NY64 Solute carrier family 2, facilitated glucose transporter member 8 chr9 GO:1903046 Not Cancer Driver No 28 0.059 19 0 0.0 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:1903046 Not Cancer Driver No 271 0.148 1573 232 0.147 0
SMC2 SMC2 O95347 Structural maintenance of chromosomes protein 2 chr9 GO:1903046 Not Cancer Driver No 145 0.121 573 88 0.154 0
SMC4_ENST00000344722 SMC4 Q9NTJ3 Structural maintenance of chromosomes protein 4 chr3 GO:1903046 Not Cancer Driver No 175 0.136 539 55 0.102 0
SPATA22_ENST00000397168 SPATA22 Q8NHS9 Spermatogenesis-associated protein 22 chr17 GO:1903046 Not Cancer Driver No 71 0.196 220 40 0.182 0
SPIRE1 SPIRE1 Q08AE8 Protein spire homolog 1 chr18 GO:1903046 Not Cancer Driver No 78 0.103 414 48 0.116 0
SPIRE2 SPIRE2 Q8WWL2 Protein spire homolog 2 chr16 GO:1903046 Not Cancer Driver No 79 0.111 344 43 0.125 0
SPO11 SPO11 Q9Y5K1 Meiotic recombination protein SPO11 chr20 GO:1903046 Not Cancer Driver No 59 0.149 26 5 0.192 0
STAG3_ENST00000426455 STAG3 Q9UJ98 Cohesin subunit SA-3 chr7 GO:1903046 Not Cancer Driver No 153 0.125 388 59 0.152 0
SUN1 SUN1 O94901 SUN domain-containing protein 1 chr7 GO:1903046 Not Cancer Driver No 109 0.139 246 26 0.106 0
SYCE1L SYCE1L A8MT33 Synaptonemal complex central element protein 1-like chr16 GO:1903046 Not Cancer Driver No 19 0.079 170 16 0.094 0
SYCE1_ENST00000343131 SYCE1 Q8N0S2 Synaptonemal complex central element protein 1 chr10 GO:1903046 Not Cancer Driver No 70 0.199 251 50 0.199 0
SYCE2 SYCE2 Q6PIF2 Synaptonemal complex central element protein 2 chr19 GO:1903046 Not Cancer Driver No 27 0.124 148 15 0.101 0
SYCE3 SYCE3 A1L190 Synaptonemal complex central element protein 3 chr22 GO:1903046 Not Cancer Driver No 8 0.091 40 2 0.05 0
SYCP1_ENST00000618516 SYCP1 Q15431 Synaptonemal complex protein 1 chr1 GO:1903046 Not Cancer Driver No 207 0.212 602 124 0.206 0
SYCP2_ENST00000371001 SYCP2 Q9BX26 Synaptonemal complex protein 2 chr20 GO:1903046 Not Cancer Driver No 247 0.161 761 121 0.159 0
SYCP3_ENST00000392924 SYCP3 Q8IZU3 Synaptonemal complex protein 3 chr12 GO:1903046 Not Cancer Driver No 30 0.127 124 12 0.097 0
TDRD9 TDRD9 Q8NDG6 ATP-dependent RNA helicase TDRD9 chr14 GO:1903046 Not Cancer Driver No 156 0.113 108 0 0.0 0
TERB1_ENST00000558713 TERB1 Q8NA31 Telomere repeats-binding bouquet formation protein 1 chr16 GO:1903046 Not Cancer Driver No 33 0.045 201 14 0.07 0
TERB2 TERB2 Q8NHR7 Telomere repeats-binding bouquet formation protein 2 chr15 GO:1903046 Not Cancer Driver No 38 0.173 35 5 0.143 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 GO:1903046 Not Cancer Driver No 63 0.144 220 34 0.155 0
TEX11_ENST00000344304 TEX11 Q8IYF3 Testis-expressed protein 11 chrX GO:1903046 Not Cancer Driver No 139 0.148 30 3 0.1 2
TEX12 TEX12 Q9BXU0 Testis-expressed protein 12 chr11 GO:1903046 Not Cancer Driver No 10 0.081 35 3 0.086 0
TEX15_ENST00000256246 TEX15 Q9BXT5 Testis-expressed protein 15 chr8 GO:1903046 Not Cancer Driver No 479 0.172 1258 223 0.177 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 GO:1903046 Compendium Yes 150 0.098 508 59 0.116 0
TRIM75P TRIM75 A6NK02 Tripartite motif-containing protein 75 chr4 GO:1903046 Not Cancer Driver No 21 0.045 64 2 0.031 0
TRIP13 TRIP13 Q15645 Pachytene checkpoint protein 2 homolog chr5 GO:1903046 Not Cancer Driver No 62 0.144 30 6 0.2 1
TTK TTK P33981 Dual specificity protein kinase TTK chr6 GO:1903046 Not Cancer Driver No 136 0.159 352 46 0.131 0
TUBB8 TUBB8 Q3ZCM7 Tubulin beta-8 chain chr10 GO:1903046 Not Cancer Driver No 103 0.232 53 18 0.34 13
TUBG1 TUBG1 P23258 Tubulin gamma-1 chain chr17 GO:1903046 Not Cancer Driver No 51 0.113 44 10 0.227 3
TUBG2 TUBG2 Q9NRH3 Tubulin gamma-2 chain chr17 GO:1903046 Not Cancer Driver No 51 0.113 48 4 0.083 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 GO:1903046 Not Cancer Driver No 20 0.087 102 8 0.078 0
UBE2B UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:1903046 Not Cancer Driver No 13 0.086 68 6 0.088 0
UBR2 UBR2 Q8IWV8 E3 ubiquitin-protein ligase UBR2 chr6 GO:1903046 Not Cancer Driver No 172 0.098 228 30 0.132 0
WASHC5 WASHC5 Q12768 WASH complex subunit 5 chr8 GO:1903046 Not Cancer Driver No 152 0.131 23 6 0.261 6
WEE2 WEE2 P0C1S8 Wee1-like protein kinase 2 chr7 GO:1903046 Not Cancer Driver No 104 0.183 345 65 0.188 1
ZSCAN21 ZSCAN21 Q9Y5A6 Zinc finger and SCAN domain-containing protein 21 chr7 GO:1903046 Not Cancer Driver No 68 0.144 252 38 0.151 0