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Total number of protein in "GO:1903038" GO term:  86

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:1903038 Not Cancer Driver No 61 0.148 93 11 0.118 0
ADTRP_ENST00000414691 ADTRP Q96IZ2 Androgen-dependent TFPI-regulating protein chr6 GO:1903038 Not Cancer Driver No 41 0.178 2 0 0.0 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:1903038 Census, Compendium Yes 108 0.225 158 24 0.152 4
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:1903038 Not Cancer Driver No 59 0.171 61 12 0.197 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:1903038 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:1903038 Not Cancer Driver No 25 0.071 58 3 0.052 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:1903038 Not Cancer Driver No 65 0.158 63 8 0.127 86
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:1903038 Census, Compendium Yes 134 0.19 328 67 0.204 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:1903038 Not Cancer Driver No 86 0.211 142 26 0.183 5
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:1903038 Not Cancer Driver No 92 0.176 24 2 0.083 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:1903038 Census Yes 32 0.116 62 5 0.081 0
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 GO:1903038 Census, Compendium Yes 39 0.214 94 17 0.181 0
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:1903038 Census Yes 160 0.163 562 104 0.185 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:1903038 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCL25 CCL25 O15444 C-C motif chemokine 25 chr19 GO:1903038 Not Cancer Driver No 20 0.133 26 6 0.231 0
CCL28 CCL28 Q9NRJ3 C-C motif chemokine 28 chr5 GO:1903038 Not Cancer Driver No 17 0.134 48 8 0.167 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:1903038 Census Yes 29 0.1 54 9 0.167 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:1903038 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:1903038 Census Yes 31 0.105 185 20 0.108 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:1903038 Not Cancer Driver No 64 0.122 241 25 0.104 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:1903038 Not Cancer Driver No 64 0.163 135 14 0.104 0
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 GO:1903038 Not Cancer Driver No 37 0.166 3 0 0.0 1
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:1903038 Not Cancer Driver No 16 0.172 0 0 0.0 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:1903038 Census, Compendium Yes 275 0.219 314 41 0.131 1
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:1903038 Census Yes 51 0.165 99 30 0.303 0
FGL2 FGL2 Q14314 Fibroleukin chr7 GO:1903038 Not Cancer Driver No 71 0.162 70 12 0.171 0
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:1903038 Not Cancer Driver No 25 0.059 279 18 0.065 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:1903038 Not Cancer Driver No 38 0.088 186 16 0.086 10
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:1903038 Not Cancer Driver No 385 0.244 1352 327 0.242 7
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:1903038 Not Cancer Driver No 69 0.229 17 2 0.118 3
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:1903038 Not Cancer Driver No 55 0.158 27 2 0.074 11
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:1903038 Not Cancer Driver No 107 0.219 412 98 0.238 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:1903038 Not Cancer Driver No 25 0.116 203 20 0.099 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:1903038 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:1903038 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNL1 IFNL1 Q8IU54 Interferon lambda-1 chr19 GO:1903038 Not Cancer Driver No 24 0.12 49 8 0.163 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:1903038 Not Cancer Driver No 58 0.141 111 15 0.135 6
IL2 IL2 P60568 Interleukin-2 chr4 GO:1903038 Census Yes 24 0.157 6 1 0.167 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:1903038 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:1903038 Not Cancer Driver No 133 0.161 420 64 0.152 0
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:1903038 Compendium Yes 49 0.151 228 31 0.136 2
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:1903038 Not Cancer Driver No 95 0.105 335 42 0.125 0
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:1903038 Census, Compendium Yes 167 0.149 63 10 0.159 7
LAG3 LAG3 P18627 Lymphocyte activation gene 3 protein chr12 GO:1903038 Not Cancer Driver No 47 0.09 208 11 0.053 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:1903038 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS7B LGALS7B P47929 Galectin-7 chr19 GO:1903038 Not Cancer Driver No 14 0.103 54 5 0.093 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:1903038 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGALS9B_ENST00000423676 LGALS9B Q3B8N2 Galectin-9B chr17 GO:1903038 Not Cancer Driver No 43 0.121 86 19 0.221 0
LGALS9C LGALS9C Q6DKI2 Galectin-9C chr17 GO:1903038 Not Cancer Driver No 32 0.09 80 6 0.075 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:1903038 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:1903038 Not Cancer Driver No 162 0.362 277 115 0.415 0
LOXL3 LOXL3 P58215 Lysyl oxidase homolog 3 chr2 GO:1903038 Not Cancer Driver No 91 0.121 86 17 0.198 0
LRRC32_ENST00000404995 LRRC32 Q14392 Transforming growth factor beta activator LRRC32 chr11 GO:1903038 Not Cancer Driver No 130 0.196 28 4 0.143 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:1903038 Not Cancer Driver No 15 0.105 20 2 0.1 0
MIA3 MIA3 Q5JRA6 Transport and Golgi organization protein 1 homolog chr1 GO:1903038 Not Cancer Driver No 222 0.116 1490 178 0.119 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:1903038 Not Cancer Driver No 247 0.219 51 10 0.196 4
NRARP NRARP Q7Z6K4 Notch-regulated ankyrin repeat-containing protein chr9 GO:1903038 Not Cancer Driver No 9 0.079 11 1 0.091 0
PDCD1LG2 PDCD1LG2 Q9BQ51 Programmed cell death 1 ligand 2 chr9 GO:1903038 Census, Compendium Yes 33 0.121 41 13 0.317 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:1903038 Not Cancer Driver No 63 0.135 68 9 0.132 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:1903038 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 GO:1903038 Census, Compendium Yes 39 0.102 66 11 0.167 17
PRNP PRNP P04156 Major prion protein chr20 GO:1903038 Not Cancer Driver No 36 0.142 115 7 0.061 18
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:1903038 Not Cancer Driver No 57 0.137 120 14 0.117 0
RAG2 RAG2 P55895 V(D)J recombination-activating protein 2 chr11 GO:1903038 Not Cancer Driver No 118 0.224 85 23 0.271 6
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:1903038 Not Cancer Driver No 158 0.139 796 115 0.144 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 GO:1903038 Not Cancer Driver No 128 0.107 703 81 0.115 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:1903038 Not Cancer Driver No 131 0.123 421 76 0.181 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:1903038 Census, Compendium Yes 81 0.179 360 58 0.161 2
RUNX3_ENST00000308873 RUNX3 Q13761 Runt-related transcription factor 3 chr1 GO:1903038 Not Cancer Driver No 59 0.142 331 45 0.136 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:1903038 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:1903038 Not Cancer Driver No 56 0.121 139 14 0.101 81
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:1903038 Not Cancer Driver No 40 0.094 139 0 0.0 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:1903038 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:1903038 Not Cancer Driver No 84 0.157 297 46 0.155 0
TARM1_ENST00000432826 TARM1 B6A8C7 T-cell-interacting, activating receptor on myeloid cells protein 1 chr19 GO:1903038 Not Cancer Driver No 13 0.048 21 1 0.048 0
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:1903038 Not Cancer Driver No 70 0.131 348 50 0.144 0
TMEM131L_ENST00000409663 TMEM131L A2VDJ0 Transmembrane protein 131-like chr4 GO:1903038 Not Cancer Driver No 188 0.117 448 47 0.105 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:1903038 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:1903038 Not Cancer Driver No 28 0.153 1 0 0.0 0
TWSG1 TWSG1 Q9GZX9 Twisted gastrulation protein homolog 1 chr18 GO:1903038 Not Cancer Driver No 27 0.121 19 3 0.158 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:1903038 Not Cancer Driver No 52 0.167 135 19 0.141 0
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:1903038 Not Cancer Driver No 278 0.117 1959 223 0.114 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:1903038 Not Cancer Driver No 28 0.246 35 11 0.314 0
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:1903038 Compendium Yes 103 0.191 353 70 0.198 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:1903038 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:1903038 Not Cancer Driver No 22 0.076 187 17 0.091 0