Total number of protein in "GO:1902911" GO term: 82
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVR1B_ENST00000257963 | ACVR1B | P36896 | Activin receptor type-1B | chr12 | GO:1902911 | Census | Yes | 114 | 0.226 | 0 | 0 | 0.0 | 0 |
| ACVR1C | ACVR1C | Q8NER5 | Activin receptor type-1C | chr2 | GO:1902911 | Not Cancer Driver | No | 90 | 0.183 | 3 | 1 | 0.333 | 0 |
| ACVR1_ENST00000434821 | ACVR1 | Q04771 | Activin receptor type-1 | chr2 | GO:1902911 | Census, Compendium | Yes | 78 | 0.153 | 21 | 8 | 0.381 | 8 |
| ACVR2A_ENST00000404590 | ACVR2A | P27037 | Activin receptor type-2A | chr2 | GO:1902911 | Census, Compendium | Yes | 98 | 0.191 | 56 | 6 | 0.107 | 0 |
| ACVR2B | ACVR2B | Q13705 | Activin receptor type-2B | chr3 | GO:1902911 | Not Cancer Driver | No | 83 | 0.162 | 70 | 14 | 0.2 | 2 |
| AMHR2 | AMHR2 | Q16671 | Anti-Muellerian hormone type-2 receptor | chr12 | GO:1902911 | Not Cancer Driver | No | 77 | 0.134 | 117 | 7 | 0.06 | 8 |
| ATG101 | ATG101 | Q9BSB4 | Autophagy-related protein 101 | chr12 | GO:1902911 | Not Cancer Driver | No | 21 | 0.096 | 5 | 0 | 0.0 | 0 |
| ATG13_ENST00000359513 | ATG13 | O75143 | Autophagy-related protein 13 | chr11 | GO:1902911 | Not Cancer Driver | No | 55 | 0.106 | 205 | 27 | 0.132 | 0 |
| BCCIP_ENST00000278100 | BCCIP | Q9P287 | BRCA2 and CDKN1A-interacting protein | chr10 | GO:1902911 | Not Cancer Driver | No | 35 | 0.111 | 99 | 16 | 0.162 | 0 |
| CALM2 | CALM2 | P0DP24 | Calmodulin-2 | chr2 | GO:1902911 | Not Cancer Driver | No | 18 | 0.121 | 115 | 13 | 0.113 | 8 |
| CCNA1 | CCNA1 | P78396 | Cyclin-A1 | chr13 | GO:1902911 | Not Cancer Driver | No | 112 | 0.241 | 82 | 21 | 0.256 | 0 |
| CCNA2_ENST00000618014 | CCNA2 | P20248 | Cyclin-A2 | chr4 | GO:1902911 | Not Cancer Driver | No | 45 | 0.104 | 186 | 19 | 0.102 | 0 |
| CCNB1 | CCNB1 | P14635 | G2/mitotic-specific cyclin-B1 | chr5 | GO:1902911 | Not Cancer Driver | No | 49 | 0.113 | 145 | 14 | 0.097 | 0 |
| CCND1 | CCND1 | P24385 | G1/S-specific cyclin-D1 | chr11 | GO:1902911 | Census, Compendium | Yes | 55 | 0.186 | 31 | 25 | 0.806 | 0 |
| CCND2 | CCND2 | P30279 | G1/S-specific cyclin-D2 | chr12 | GO:1902911 | Census, Compendium | Yes | 39 | 0.135 | 29 | 7 | 0.241 | 5 |
| CCND3 | CCND3 | P30281 | G1/S-specific cyclin-D3 | chr6 | GO:1902911 | Census, Compendium | Yes | 29 | 0.099 | 46 | 8 | 0.174 | 0 |
| CCNE1 | CCNE1 | P24864 | G1/S-specific cyclin-E1 | chr19 | GO:1902911 | Census | Yes | 63 | 0.154 | 142 | 26 | 0.183 | 0 |
| CCNE2_ENST00000308108 | CCNE2 | O96020 | G1/S-specific cyclin-E2 | chr8 | GO:1902911 | Not Cancer Driver | No | 46 | 0.114 | 68 | 9 | 0.132 | 0 |
| CCNH | CCNH | P51946 | Cyclin-H | chr5 | GO:1902911 | Not Cancer Driver | No | 40 | 0.124 | 28 | 4 | 0.143 | 0 |
| CCNK | CCNK | O75909 | Cyclin-K | chr14 | GO:1902911 | Not Cancer Driver | No | 39 | 0.067 | 347 | 15 | 0.043 | 1 |
| CCNO | CCNO | P22674 | Cyclin-O | chr5 | GO:1902911 | Not Cancer Driver | No | 18 | 0.051 | 101 | 3 | 0.03 | 2 |
| CCNT1 | CCNT1 | O60563 | Cyclin-T1 | chr12 | GO:1902911 | Not Cancer Driver | No | 85 | 0.117 | 495 | 61 | 0.123 | 0 |
| CCNT2 | CCNT2 | O60583 | Cyclin-T2 | chr2 | GO:1902911 | Not Cancer Driver | No | 76 | 0.104 | 471 | 52 | 0.11 | 0 |
| CCNY | CCNY | Q8ND76 | Cyclin-Y | chr10 | GO:1902911 | Not Cancer Driver | No | 38 | 0.111 | 94 | 6 | 0.064 | 0 |
| CDK1 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | GO:1902911 | Not Cancer Driver | No | 40 | 0.135 | 1 | 0 | 0.0 | 0 |
| CDK12 | CDK12 | Q9NYV4 | Cyclin-dependent kinase 12 | chr17 | GO:1902911 | Census, Compendium | Yes | 225 | 0.151 | 1202 | 160 | 0.133 | 0 |
| CDK13 | CDK13 | Q14004 | Cyclin-dependent kinase 13 | chr7 | GO:1902911 | Not Cancer Driver | No | 155 | 0.103 | 1138 | 99 | 0.087 | 6 |
| CDK14 | CDK14 | O94921 | Cyclin-dependent kinase 14 | chr7 | GO:1902911 | Not Cancer Driver | No | 93 | 0.198 | 154 | 21 | 0.136 | 0 |
| CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | GO:1902911 | Not Cancer Driver | No | 24 | 0.081 | 0 | 0 | 0.0 | 0 |
| CDK4 | CDK4 | P11802 | Cyclin-dependent kinase 4 | chr12 | GO:1902911 | Census, Compendium | Yes | 52 | 0.172 | 52 | 5 | 0.096 | 3 |
| CDK5 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:1902911 | Not Cancer Driver | No | 48 | 0.164 | 5 | 1 | 0.2 | 0 |
| CDK5R1 | CDK5R1 | Q15078 | Cyclin-dependent kinase 5 activator 1 | chr17 | GO:1902911 | Not Cancer Driver | No | 35 | 0.114 | 103 | 16 | 0.155 | 0 |
| CDK5R2 | CDK5R2 | Q13319 | Cyclin-dependent kinase 5 activator 2 | chr2 | GO:1902911 | Not Cancer Driver | No | 14 | 0.038 | 204 | 5 | 0.025 | 0 |
| CDK6 | CDK6 | Q00534 | Cyclin-dependent kinase 6 | chr7 | GO:1902911 | Census | Yes | 40 | 0.123 | 24 | 3 | 0.125 | 1 |
| CDK7 | CDK7 | P50613 | Cyclin-dependent kinase 7 | chr5 | GO:1902911 | Not Cancer Driver | No | 41 | 0.118 | 38 | 5 | 0.132 | 0 |
| CDK9 | CDK9 | P50750 | Cyclin-dependent kinase 9 | chr9 | GO:1902911 | Not Cancer Driver | No | 50 | 0.134 | 34 | 2 | 0.059 | 0 |
| CDKN2D_ENST00000335766 | CDKN2D | P55273 | Cyclin-dependent kinase 4 inhibitor D | chr19 | GO:1902911 | Not Cancer Driver | No | 17 | 0.102 | 44 | 3 | 0.068 | 0 |
| CHUK | CHUK | O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha | chr10 | GO:1902911 | Not Cancer Driver | No | 74 | 0.099 | 116 | 9 | 0.078 | 0 |
| CNTD2 | CCNP | Q9H8S5 | Cyclin-P | chr19 | GO:1902911 | Not Cancer Driver | No | 25 | 0.081 | 55 | 3 | 0.055 | 0 |
| DAPK1_ENST00000622514 | DAPK1 | P53355 | Death-associated protein kinase 1 | chr9 | GO:1902911 | Not Cancer Driver | No | 193 | 0.135 | 114 | 11 | 0.096 | 0 |
| ERC1 | ERC1 | Q8IUD2 | ELKS/Rab6-interacting/CAST family member 1 | chr12 | GO:1902911 | Census | Yes | 127 | 0.114 | 1013 | 119 | 0.117 | 0 |
| ERN1 | ERN1 | O75460 | Serine/threonine-protein kinase/endoribonuclease IRE1 | chr17 | GO:1902911 | Not Cancer Driver | No | 125 | 0.128 | 250 | 28 | 0.112 | 0 |
| IGF1R | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:1902911 | Not Cancer Driver | No | 183 | 0.134 | 265 | 37 | 0.14 | 6 |
| IKBKB | IKBKB | O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | chr8 | GO:1902911 | Census, Compendium | Yes | 106 | 0.14 | 211 | 31 | 0.147 | 1 |
| IKBKG_ENST00000611071 | IKBKG | Q9Y6K9 | NF-kappa-B essential modulator | chrX | GO:1902911 | Not Cancer Driver | No | 6 | 0.014 | 301 | 6 | 0.02 | 22 |
| INSR | INSR | P06213 | Insulin receptor | chr19 | GO:1902911 | Not Cancer Driver | No | 190 | 0.137 | 280 | 57 | 0.204 | 64 |
| INSRR | INSRR | P14616 | Insulin receptor-related protein | chr1 | GO:1902911 | Not Cancer Driver | No | 262 | 0.202 | 228 | 37 | 0.162 | 0 |
| IRS1 | IRS1 | P35568 | Insulin receptor substrate 1 | chr2 | GO:1902911 | Not Cancer Driver | No | 161 | 0.13 | 1072 | 133 | 0.124 | 2 |
| LAS1L | LAS1L | Q9Y4W2 | Ribosomal biogenesis protein LAS1L | chrX | GO:1902911 | Not Cancer Driver | No | 100 | 0.136 | 279 | 49 | 0.176 | 0 |
| MAP3K5 | MAP3K5 | Q99683 | Mitogen-activated protein kinase kinase kinase 5 | chr6 | GO:1902911 | Not Cancer Driver | No | 197 | 0.143 | 242 | 29 | 0.12 | 0 |
| MNAT1 | MNAT1 | P51948 | CDK-activating kinase assembly factor MAT1 | chr14 | GO:1902911 | Not Cancer Driver | No | 23 | 0.074 | 64 | 2 | 0.031 | 0 |
| NEK10_ENST00000429845 | NEK10 | Q6ZWH5 | Serine/threonine-protein kinase Nek10 | chr3 | GO:1902911 | Not Cancer Driver | No | 213 | 0.182 | 281 | 60 | 0.214 | 0 |
| PARD3 | PARD3 | Q8TEW0 | Partitioning defective 3 homolog | chr10 | GO:1902911 | Not Cancer Driver | No | 200 | 0.147 | 1144 | 170 | 0.149 | 2 |
| PARD6A | PARD6A | Q9NPB6 | Partitioning defective 6 homolog alpha | chr16 | GO:1902911 | Not Cancer Driver | No | 25 | 0.072 | 177 | 13 | 0.073 | 0 |
| PHKA1 | PHKA1 | P46020 | Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform | chrX | GO:1902911 | Not Cancer Driver | No | 228 | 0.186 | 188 | 43 | 0.229 | 1 |
| PHKA2 | PHKA2 | P46019 | Phosphorylase b kinase regulatory subunit alpha, liver isoform | chrX | GO:1902911 | Not Cancer Driver | No | 199 | 0.161 | 193 | 37 | 0.192 | 17 |
| PHKB | PHKB | Q93100 | Phosphorylase b kinase regulatory subunit beta | chr16 | GO:1902911 | Not Cancer Driver | No | 147 | 0.134 | 98 | 9 | 0.092 | 1 |
| PHKG1_ENST00000297373 | PHKG1 | Q16816 | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | chr7 | GO:1902911 | Not Cancer Driver | No | 58 | 0.15 | 23 | 4 | 0.174 | 0 |
| PHKG2 | PHKG2 | P15735 | Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | chr16 | GO:1902911 | Not Cancer Driver | No | 48 | 0.118 | 50 | 6 | 0.12 | 4 |
| PRKAA1_ENST00000397128 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | GO:1902911 | Not Cancer Driver | No | 72 | 0.129 | 124 | 17 | 0.137 | 0 |
| PRKAA2 | PRKAA2 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | chr1 | GO:1902911 | Not Cancer Driver | No | 128 | 0.232 | 98 | 26 | 0.265 | 0 |
| PRKAB1 | PRKAB1 | Q9Y478 | 5'-AMP-activated protein kinase subunit beta-1 | chr12 | GO:1902911 | Not Cancer Driver | No | 39 | 0.144 | 124 | 13 | 0.105 | 0 |
| PRKAB2 | PRKAB2 | O43741 | 5'-AMP-activated protein kinase subunit beta-2 | chr1 | GO:1902911 | Not Cancer Driver | No | 31 | 0.114 | 110 | 12 | 0.109 | 0 |
| PRKAG1_ENST00000548065 | PRKAG1 | P54619 | 5'-AMP-activated protein kinase subunit gamma-1 | chr12 | GO:1902911 | Not Cancer Driver | No | 35 | 0.106 | 25 | 2 | 0.08 | 0 |
| PRKAG2 | PRKAG2 | Q9UGJ0 | 5'-AMP-activated protein kinase subunit gamma-2 | chr7 | GO:1902911 | Not Cancer Driver | No | 76 | 0.134 | 240 | 45 | 0.188 | 7 |
| PRKAG3_ENST00000529249 | PRKAG3 | Q9UGI9 | 5'-AMP-activated protein kinase subunit gamma-3 | chr2 | GO:1902911 | Not Cancer Driver | No | 74 | 0.151 | 144 | 25 | 0.174 | 0 |
| PRKAR1A_ENST00000536854 | PRKAR1A | P10644 | cAMP-dependent protein kinase type I-alpha regulatory subunit | chr17 | GO:1902911 | Census, Compendium | Yes | 39 | 0.102 | 66 | 11 | 0.167 | 17 |
| PRKAR2A | PRKAR2A | P13861 | cAMP-dependent protein kinase type II-alpha regulatory subunit | chr3 | GO:1902911 | Not Cancer Driver | No | 37 | 0.092 | 149 | 13 | 0.087 | 0 |
| PRKCI | PRKCI | P41743 | Protein kinase C iota type | chr3 | GO:1902911 | Not Cancer Driver | No | 110 | 0.185 | 120 | 16 | 0.133 | 0 |
| PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:1902911 | Not Cancer Driver | No | 538 | 0.13 | 421 | 61 | 0.145 | 2 |
| PSG9 | PSG9 | Q00887 | Pregnancy-specific beta-1-glycoprotein 9 | chr19 | GO:1902911 | Not Cancer Driver | No | 125 | 0.293 | 40 | 8 | 0.2 | 0 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:1902911 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| PYDC1 | PYDC1 | Q8WXC3 | Pyrin domain-containing protein 1 | chr16 | GO:1902911 | Not Cancer Driver | No | 28 | 0.315 | 0 | 0 | 0.0 | 0 |
| RB1CC1 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | GO:1902911 | Not Cancer Driver | No | 202 | 0.127 | 578 | 75 | 0.13 | 0 |
| SESN2 | SESN2 | P58004 | Sestrin-2 | chr1 | GO:1902911 | Not Cancer Driver | No | 74 | 0.154 | 147 | 26 | 0.177 | 0 |
| SMCR8 | SMCR8 | Q8TEV9 | Guanine nucleotide exchange protein SMCR8 | chr17 | GO:1902911 | Not Cancer Driver | No | 107 | 0.114 | 357 | 38 | 0.106 | 0 |
| TGFBR1_ENST00000374994 | TGFBR1 | P36897 | TGF-beta receptor type-1 | chr9 | GO:1902911 | Not Cancer Driver | No | 86 | 0.171 | 23 | 3 | 0.13 | 15 |
| TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:1902911 | Census, Compendium | Yes | 106 | 0.187 | 60 | 16 | 0.267 | 25 |
| TRIM40_ENST00000376724 | TRIM40 | Q6P9F5 | E3 ubiquitin ligase TRIM40 | chr6 | GO:1902911 | Not Cancer Driver | No | 44 | 0.171 | 84 | 12 | 0.143 | 0 |
| ULK1 | ULK1 | O75385 | Serine/threonine-protein kinase ULK1 | chr12 | GO:1902911 | Not Cancer Driver | No | 142 | 0.135 | 588 | 77 | 0.131 | 0 |
| XRCC5_ENST00000392132 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | GO:1902911 | Not Cancer Driver | No | 87 | 0.119 | 118 | 11 | 0.093 | 0 |
| XRCC6 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | GO:1902911 | Not Cancer Driver | No | 66 | 0.108 | 140 | 12 | 0.086 | 0 |