Total number of protein in "GO:1902806" GO term: 87
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAM17 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:1902806 | Not Cancer Driver | No | 80 | 0.097 | 182 | 17 | 0.093 | 0 |
| ADAMTS1 | ADAMTS1 | Q9UHI8 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | chr21 | GO:1902806 | Not Cancer Driver | No | 135 | 0.14 | 272 | 32 | 0.118 | 0 |
| AIF1 | AIF1 | P55008 | Allograft inflammatory factor 1 | chr6 | GO:1902806 | Not Cancer Driver | No | 14 | 0.095 | 61 | 6 | 0.098 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:1902806 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| ANKRD17 | ANKRD17 | O75179 | Ankyrin repeat domain-containing protein 17 | chr4 | GO:1902806 | Not Cancer Driver | No | 312 | 0.12 | 1790 | 221 | 0.123 | 9 |
| ANXA1_ENST00000257497 | ANXA1 | P04083 | Annexin A1 | chr9 | GO:1902806 | Not Cancer Driver | No | 59 | 0.171 | 61 | 12 | 0.197 | 0 |
| APBB1 | APBB1 | O00213 | Amyloid beta precursor protein binding family B member 1 | chr11 | GO:1902806 | Not Cancer Driver | No | 105 | 0.148 | 399 | 58 | 0.145 | 0 |
| APC | APC | P25054 | Adenomatous polyposis coli protein | chr5 | GO:1902806 | Census, Compendium | Yes | 412 | 0.145 | 2406 | 345 | 0.143 | 22 |
| APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:1902806 | Not Cancer Driver | No | 34 | 0.107 | 103 | 14 | 0.136 | 0 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:1902806 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| C10orf99 | GPR15L | Q6UWK7 | Protein GPR15L | chr10 | GO:1902806 | Not Cancer Driver | No | 11 | 0.136 | 0 | 0 | 0.0 | 0 |
| CASP2 | CASP2 | P42575 | Caspase-2 | chr7 | GO:1902806 | Not Cancer Driver | No | 63 | 0.139 | 42 | 12 | 0.286 | 0 |
| CCND1 | CCND1 | P24385 | G1/S-specific cyclin-D1 | chr11 | GO:1902806 | Census, Compendium | Yes | 55 | 0.186 | 31 | 25 | 0.806 | 0 |
| CCND2 | CCND2 | P30279 | G1/S-specific cyclin-D2 | chr12 | GO:1902806 | Census, Compendium | Yes | 39 | 0.135 | 29 | 7 | 0.241 | 5 |
| CCND3 | CCND3 | P30281 | G1/S-specific cyclin-D3 | chr6 | GO:1902806 | Census, Compendium | Yes | 29 | 0.099 | 46 | 8 | 0.174 | 0 |
| CDC6 | CDC6 | Q99741 | Cell division control protein 6 homolog | chr17 | GO:1902806 | Not Cancer Driver | No | 57 | 0.102 | 170 | 15 | 0.088 | 1 |
| CDK10 | CDK10 | Q15131 | Cyclin-dependent kinase 10 | chr16 | GO:1902806 | Not Cancer Driver | No | 42 | 0.117 | 30 | 4 | 0.133 | 0 |
| CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | GO:1902806 | Not Cancer Driver | No | 24 | 0.081 | 0 | 0 | 0.0 | 0 |
| CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:1902806 | Census, Compendium | Yes | 48 | 0.293 | 121 | 30 | 0.248 | 0 |
| CDKN1B | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:1902806 | Census, Compendium | Yes | 19 | 0.096 | 198 | 19 | 0.096 | 0 |
| CDKN2D_ENST00000335766 | CDKN2D | P55273 | Cyclin-dependent kinase 4 inhibitor D | chr19 | GO:1902806 | Not Cancer Driver | No | 17 | 0.102 | 44 | 3 | 0.068 | 0 |
| CENPJ | CENPJ | Q9HC77 | Centromere protein J | chr13 | GO:1902806 | Not Cancer Driver | No | 176 | 0.132 | 1176 | 158 | 0.134 | 1 |
| CHEK2_ENST00000405598 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | GO:1902806 | Census, Compendium | Yes | 335 | 0.617 | 157 | 130 | 0.828 | 13 |
| CPSF3 | CPSF3 | Q9UKF6 | Cleavage and polyadenylation specificity factor subunit 3 | chr2 | GO:1902806 | Not Cancer Driver | No | 78 | 0.114 | 56 | 9 | 0.161 | 0 |
| CRADD_ENST00000332896 | CRADD | P78560 | Death domain-containing protein CRADD | chr12 | GO:1902806 | Not Cancer Driver | No | 35 | 0.176 | 45 | 5 | 0.111 | 1 |
| CUL4A | CUL4A | Q13619 | Cullin-4A | chr13 | GO:1902806 | Not Cancer Driver | No | 64 | 0.084 | 102 | 2 | 0.02 | 0 |
| CUL4B | CUL4B | Q13620 | Cullin-4B | chrX | GO:1902806 | Not Cancer Driver | No | 138 | 0.151 | 207 | 38 | 0.184 | 2 |
| CYP1A1 | CYP1A1 | P04798 | Cytochrome P450 1A1 | chr15 | GO:1902806 | Not Cancer Driver | No | 81 | 0.158 | 17 | 2 | 0.118 | 0 |
| DDX3X_ENST00000629496 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:1902806 | Census, Compendium | Yes | 133 | 0.201 | 301 | 47 | 0.156 | 18 |
| EEF1AKNMT | METTL13 | Q8N6R0 | eEF1A lysine and N-terminal methyltransferase | chr1 | GO:1902806 | Not Cancer Driver | No | 91 | 0.13 | 76 | 16 | 0.211 | 0 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:1902806 | Census, Compendium | Yes | 444 | 0.367 | 223 | 35 | 0.157 | 1 |
| EIF4G1_ENST00000346169 | EIF4G1 | Q04637 | Eukaryotic translation initiation factor 4 gamma 1 | chr3 | GO:1902806 | Not Cancer Driver | No | 229 | 0.143 | 1079 | 153 | 0.142 | 2 |
| FBXO31 | FBXO31 | Q5XUX0 | F-box only protein 31 | chr16 | GO:1902806 | Not Cancer Driver | No | 72 | 0.134 | 231 | 30 | 0.13 | 0 |
| FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | GO:1902806 | Census, Compendium | Yes | 322 | 0.455 | 230 | 38 | 0.165 | 0 |
| FGF10 | FGF10 | O15520 | Fibroblast growth factor 10 | chr5 | GO:1902806 | Not Cancer Driver | No | 56 | 0.269 | 34 | 11 | 0.324 | 2 |
| GIGYF2_ENST00000409547 | GIGYF2 | Q6Y7W6 | GRB10-interacting GYF protein 2 | chr2 | GO:1902806 | Not Cancer Driver | No | 176 | 0.135 | 1096 | 158 | 0.144 | 6 |
| GML | GML | Q99445 | Glycosyl-phosphatidylinositol-anchored molecule-like protein | chr8 | GO:1902806 | Not Cancer Driver | No | 49 | 0.31 | 12 | 6 | 0.5 | 0 |
| GTSE1 | GTSE1 | Q9NYZ3 | G2 and S phase-expressed protein 1 | chr22 | GO:1902806 | Not Cancer Driver | No | 91 | 0.126 | 660 | 85 | 0.129 | 0 |
| HYAL1_ENST00000395144 | HYAL1 | Q12794 | Hyaluronidase-1 | chr3 | GO:1902806 | Not Cancer Driver | No | 47 | 0.108 | 9 | 0 | 0.0 | 1 |
| KCNA5 | KCNA5 | P22460 | Potassium voltage-gated channel subfamily A member 5 | chr12 | GO:1902806 | Not Cancer Driver | No | 213 | 0.347 | 218 | 53 | 0.243 | 0 |
| KMT2E | KMT2E | Q8IZD2 | Inactive histone-lysine N-methyltransferase 2E | chr7 | GO:1902806 | Not Cancer Driver | No | 233 | 0.125 | 1613 | 198 | 0.123 | 4 |
| LSM10 | LSM10 | Q969L4 | U7 snRNA-associated Sm-like protein LSm10 | chr1 | GO:1902806 | Not Cancer Driver | No | 21 | 0.171 | 12 | 5 | 0.417 | 0 |
| LSM11 | LSM11 | P83369 | U7 snRNA-associated Sm-like protein LSm11 | chr5 | GO:1902806 | Not Cancer Driver | No | 34 | 0.094 | 266 | 17 | 0.064 | 1 |
| MBLAC1 | MBLAC1 | A4D2B0 | Metallo-beta-lactamase domain-containing protein 1 | chr7 | GO:1902806 | Not Cancer Driver | No | 26 | 0.098 | 175 | 22 | 0.126 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:1902806 | Census, Compendium | Yes | 56 | 0.114 | 297 | 37 | 0.125 | 0 |
| MEN1 | MEN1 | O00255 | Menin | chr11 | GO:1902806 | Census, Compendium | Yes | 73 | 0.119 | 228 | 15 | 0.066 | 90 |
| MEPCE | MEPCE | Q7L2J0 | 7SK snRNA methylphosphate capping enzyme | chr7 | GO:1902806 | Not Cancer Driver | No | 76 | 0.11 | 446 | 42 | 0.094 | 0 |
| MLF1_ENST00000355893 | MLF1 | P58340 | Myeloid leukemia factor 1 | chr3 | GO:1902806 | Census | Yes | 40 | 0.149 | 243 | 37 | 0.152 | 0 |
| MN1 | MN1 | Q10571 | Transcriptional activator MN1 | chr22 | GO:1902806 | Census | Yes | 148 | 0.112 | 1283 | 140 | 0.109 | 0 |
| MTBP | MTBP | Q96DY7 | Mdm2-binding protein | chr8 | GO:1902806 | Not Cancer Driver | No | 99 | 0.11 | 259 | 27 | 0.104 | 0 |
| MUC1_ENST00000611571 | MUC1 | P15941 | Mucin-1 | chr1 | GO:1902806 | Census | Yes | 40 | 0.032 | 1050 | 19 | 0.018 | 0 |
| NACC2_ENST00000371753 | NACC2 | Q96BF6 | Nucleus accumbens-associated protein 2 | chr9 | GO:1902806 | Not Cancer Driver | No | 24 | 0.041 | 238 | 10 | 0.042 | 0 |
| NKX3-1 | NKX3-1 | Q99801 | Homeobox protein Nkx-3.1 | chr8 | GO:1902806 | Not Cancer Driver | No | 35 | 0.15 | 171 | 16 | 0.094 | 0 |
| PIDD1 | PIDD1 | Q9HB75 | p53-induced death domain-containing protein 1 | chr11 | GO:1902806 | Not Cancer Driver | No | 93 | 0.102 | 137 | 14 | 0.102 | 0 |
| PLCB1 | PLCB1 | Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | chr20 | GO:1902806 | Not Cancer Driver | No | 313 | 0.257 | 481 | 104 | 0.216 | 0 |
| PLK2 | PLK2 | Q9NYY3 | Serine/threonine-protein kinase PLK2 | chr5 | GO:1902806 | Not Cancer Driver | No | 92 | 0.134 | 178 | 21 | 0.118 | 0 |
| PLK3 | PLK3 | Q9H4B4 | Serine/threonine-protein kinase PLK3 | chr1 | GO:1902806 | Not Cancer Driver | No | 75 | 0.116 | 202 | 15 | 0.074 | 0 |
| PLK5 | PLK5 | Q496M5 | Inactive serine/threonine-protein kinase PLK5 | chr19 | GO:1902806 | Not Cancer Driver | No | 8 | 0.024 | 215 | 4 | 0.019 | 0 |
| PLRG1 | PLRG1 | O43660 | Pleiotropic regulator 1 | chr4 | GO:1902806 | Not Cancer Driver | No | 75 | 0.146 | 204 | 25 | 0.123 | 0 |
| PML | PML | P29590 | Protein PML | chr15 | GO:1902806 | Census, Compendium | Yes | 112 | 0.127 | 312 | 34 | 0.109 | 0 |
| PRAP1 | PRAP1 | Q96NZ9 | Proline-rich acidic protein 1 | chr10 | GO:1902806 | Not Cancer Driver | No | 14 | 0.093 | 124 | 13 | 0.105 | 0 |
| PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:1902806 | Not Cancer Driver | No | 538 | 0.13 | 421 | 61 | 0.145 | 2 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:1902806 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| RDX_ENST00000343115 | RDX | P35241 | Radixin | chr11 | GO:1902806 | Not Cancer Driver | No | 71 | 0.122 | 297 | 37 | 0.125 | 1 |
| RFWD3 | RFWD3 | Q6PCD5 | E3 ubiquitin-protein ligase RFWD3 | chr16 | GO:1902806 | Census | Yes | 68 | 0.088 | 318 | 30 | 0.094 | 1 |
| RGCC | RGCC | Q9H4X1 | Regulator of cell cycle RGCC | chr13 | GO:1902806 | Not Cancer Driver | No | 9 | 0.066 | 81 | 7 | 0.086 | 0 |
| RPA2_ENST00000373912 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | GO:1902806 | Not Cancer Driver | No | 28 | 0.104 | 114 | 16 | 0.14 | 0 |
| RPL26 | RPL26 | P61254 | 60S ribosomal protein L26 | chr17 | GO:1902806 | Not Cancer Driver | No | 16 | 0.11 | 114 | 13 | 0.114 | 0 |
| RPS27L | RPS27L | Q71UM5 | 40S ribosomal protein S27-like | chr15 | GO:1902806 | Not Cancer Driver | No | 4 | 0.048 | 22 | 2 | 0.091 | 0 |
| RPTOR | RPTOR | Q8N122 | Regulatory-associated protein of mTOR | chr17 | GO:1902806 | Not Cancer Driver | No | 176 | 0.132 | 241 | 21 | 0.087 | 0 |
| RRM1 | RRM1 | P23921 | Ribonucleoside-diphosphate reductase large subunit | chr11 | GO:1902806 | Not Cancer Driver | No | 74 | 0.093 | 41 | 7 | 0.171 | 0 |
| RRM2_ENST00000641198 | RRM2 | P31350 | Ribonucleoside-diphosphate reductase subunit M2 | chr2 | GO:1902806 | Not Cancer Driver | No | 40 | 0.103 | 48 | 0 | 0.0 | 0 |
| SASS6 | SASS6 | Q6UVJ0 | Spindle assembly abnormal protein 6 homolog | chr1 | GO:1902806 | Not Cancer Driver | No | 82 | 0.125 | 331 | 37 | 0.112 | 1 |
| SDE2 | SDE2 | Q6IQ49 | Replication stress response regulator SDE2 | chr1 | GO:1902806 | Not Cancer Driver | No | 56 | 0.124 | 290 | 35 | 0.121 | 0 |
| SOX2 | SOX2 | P48431 | Transcription factor SOX-2 | chr3 | GO:1902806 | Census | Yes | 39 | 0.123 | 312 | 39 | 0.125 | 0 |
| STIL_ENST00000360380 | STIL | Q15468 | SCL-interrupting locus protein | chr1 | GO:1902806 | Census, Compendium | Yes | 147 | 0.114 | 735 | 85 | 0.116 | 1 |
| SUSD2 | SUSD2 | Q9UGT4 | Sushi domain-containing protein 2 | chr22 | GO:1902806 | Compendium | Yes | 113 | 0.137 | 133 | 22 | 0.165 | 0 |
| TAF1_ENST00000373790 | TAF1 | P21675 | Transcription initiation factor TFIID subunit 1 | chrX | GO:1902806 | Not Cancer Driver | No | 379 | 0.202 | 1152 | 219 | 0.19 | 5 |
| TCIM | TCIM | Q9NR00 | Transcriptional and immune response regulator | chr8 | GO:1902806 | Not Cancer Driver | No | 21 | 0.198 | 33 | 7 | 0.212 | 0 |
| TERT | TERT | O14746 | Telomerase reverse transcriptase | chr5 | GO:1902806 | Census | Yes | 110 | 0.097 | 212 | 16 | 0.075 | 31 |
| TFDP1 | TFDP1 | Q14186 | Transcription factor Dp-1 | chr13 | GO:1902806 | Not Cancer Driver | No | 82 | 0.2 | 245 | 47 | 0.192 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:1902806 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TREX1_ENST00000625293 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:1902806 | Not Cancer Driver | No | 26 | 0.083 | 98 | 10 | 0.102 | 18 |
| TRIAP1 | TRIAP1 | O43715 | TP53-regulated inhibitor of apoptosis 1 | chr12 | GO:1902806 | Not Cancer Driver | No | 9 | 0.118 | 20 | 1 | 0.05 | 0 |
| TRIM39 | TRIM39 | Q9HCM9 | E3 ubiquitin-protein ligase TRIM39 | chr6 | GO:1902806 | Not Cancer Driver | No | 74 | 0.143 | 62 | 8 | 0.129 | 0 |
| UBE2E2_ENST00000425792 | UBE2E2 | Q96LR5 | Ubiquitin-conjugating enzyme E2 E2 | chr3 | GO:1902806 | Not Cancer Driver | No | 28 | 0.139 | 90 | 15 | 0.167 | 0 |
| WAC | WAC | Q9BTA9 | WW domain-containing adapter protein with coiled-coil | chr10 | GO:1902806 | Not Cancer Driver | No | 106 | 0.164 | 571 | 95 | 0.166 | 0 |