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Total number of protein in "GO:1902533" GO term:  389

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABRA ABRA Q8N0Z2 Actin-binding Rho-activating protein chr8 GO:1902533 Not Cancer Driver No 108 0.283 285 86 0.302 0
ADA ADA P00813 Adenosine deaminase chr20 GO:1902533 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADCYAP1R1_ENST00000304166 ADCYAP1R1 P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor chr7 GO:1902533 Not Cancer Driver No 127 0.271 0 0 0.0 0
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 GO:1902533 Not Cancer Driver No 64 0.092 67 4 0.06 9
ADGRV1_ENST00000645211 ADGRV1 Q8WXG9 Adhesion G-protein coupled receptor V1 chr5 GO:1902533 Not Cancer Driver No 1124 0.178 496 77 0.155 2
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:1902533 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:1902533 Not Cancer Driver No 23 0.069 0 0 0.0 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:1902533 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:1902533 Not Cancer Driver No 52 0.126 35 4 0.114 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:1902533 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGT AGT P01019 Angiotensinogen chr1 GO:1902533 Not Cancer Driver No 85 0.179 33 10 0.303 1
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 GO:1902533 Not Cancer Driver No 215 0.121 1770 214 0.121 0
AKAP13_ENST00000394518 AKAP13 Q12802 A-kinase anchor protein 13 chr15 GO:1902533 Not Cancer Driver No 359 0.128 2091 258 0.123 0
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:1902533 Not Cancer Driver No 383 0.165 1456 240 0.165 0
ALKAL1 ALKAL1 Q6UXT8 ALK and LTK ligand 1 chr8 GO:1902533 Not Cancer Driver No 18 0.14 49 3 0.061 0
ALKAL2 ALKAL2 Q6UX46 ALK and LTK ligand 2 chr2 GO:1902533 Not Cancer Driver No 7 0.046 31 0 0.0 0
ALS2 ALS2 Q96Q42 Alsin chr2 GO:1902533 Not Cancer Driver No 194 0.117 353 36 0.102 0
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:1902533 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANKRD1 ANKRD1 Q15327 Ankyrin repeat domain-containing protein 1 chr10 GO:1902533 Not Cancer Driver No 52 0.163 83 13 0.157 0
ANKRD17 ANKRD17 O75179 Ankyrin repeat domain-containing protein 17 chr4 GO:1902533 Not Cancer Driver No 312 0.12 1790 221 0.123 9
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:1902533 Not Cancer Driver No 28 0.105 131 8 0.061 3
ARHGEF3_ENST00000296315 ARHGEF3 Q9NR81 Rho guanine nucleotide exchange factor 3 chr3 GO:1902533 Not Cancer Driver No 70 0.133 154 17 0.11 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:1902533 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 GO:1902533 Not Cancer Driver No 49 0.117 154 13 0.084 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:1902533 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:1902533 Census, Compendium Yes 338 0.128 106 14 0.132 1
AUTS2 AUTS2 Q8WXX7 Autism susceptibility gene 2 protein chr7 GO:1902533 Not Cancer Driver No 219 0.174 1218 213 0.175 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:1902533 Census, Compendium Yes 120 0.139 619 88 0.142 4
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:1902533 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:1902533 Census Yes 30 0.156 39 2 0.051 0
BBC3 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 GO:1902533 Not Cancer Driver No 20 0.077 253 20 0.079 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:1902533 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:1902533 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 GO:1902533 Census, Compendium Yes 421 0.458 899 408 0.454 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:1902533 Not Cancer Driver No 45 0.1 190 19 0.1 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 GO:1902533 Not Cancer Driver No 23 0.118 74 9 0.122 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:1902533 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:1902533 Not Cancer Driver No 86 0.211 142 26 0.183 5
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:1902533 Not Cancer Driver No 7 0.033 0 0 0.0 0
C10orf71 CEFIP Q711Q0 Cardiac-enriched FHL2-interacting protein chr10 GO:1902533 Not Cancer Driver No 229 0.16 1356 218 0.161 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 GO:1902533 Not Cancer Driver No 162 0.342 29 9 0.31 0
CAMTA1 CAMTA1 Q9Y6Y1 Calmodulin-binding transcription activator 1 chr1 GO:1902533 Census, Compendium Yes 300 0.179 883 152 0.172 0
CAT CAT P04040 Catalase chr11 GO:1902533 Not Cancer Driver No 70 0.133 176 18 0.102 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:1902533 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:1902533 Census, Compendium Yes 115 0.127 512 56 0.109 4
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 GO:1902533 Not Cancer Driver No 102 0.111 528 62 0.117 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:1902533 Not Cancer Driver No 10 0.102 7 0 0.0 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:1902533 Census Yes 42 0.191 18 10 0.556 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:1902533 Not Cancer Driver No 28 0.135 72 12 0.167 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:1902533 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:1902533 Not Cancer Driver No 39 0.141 56 6 0.107 2
CDH13_ENST00000567109 CDH13 P55290 Cadherin-13 chr16 GO:1902533 Not Cancer Driver No 168 0.236 235 59 0.251 0
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:1902533 Not Cancer Driver No 50 0.099 99 20 0.202 0
CHD5 CHD5 Q8TDI0 Chromodomain-helicase-DNA-binding protein 5 chr1 GO:1902533 Not Cancer Driver No 365 0.187 931 183 0.197 0
CHERP CHERP Q8IWX8 Calcium homeostasis endoplasmic reticulum protein chr19 GO:1902533 Not Cancer Driver No 109 0.119 707 79 0.112 0
CHP2 CHP2 O43745 Calcineurin B homologous protein 2 chr16 GO:1902533 Not Cancer Driver No 43 0.219 65 16 0.246 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:1902533 Not Cancer Driver No 24 0.126 6 1 0.167 0
CLEC16A CLEC16A Q2KHT3 Protein CLEC16A chr16 GO:1902533 Not Cancer Driver No 149 0.142 374 53 0.142 0
CLEC6A CLEC6A Q6EIG7 C-type lectin domain family 6 member A chr12 GO:1902533 Not Cancer Driver No 41 0.196 7 0 0.0 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:1902533 Not Cancer Driver No 43 0.174 46 2 0.043 0
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:1902533 Census Yes 402 0.274 1182 337 0.285 103
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:1902533 Not Cancer Driver No 20 0.097 7 0 0.0 0
CTNS_ENST00000046640 CTNS O60931 Cystinosin chr17 GO:1902533 Not Cancer Driver No 34 0.093 0 0 0.0 31
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:1902533 Not Cancer Driver No 131 0.11 681 68 0.1 0
DCN DCN P07585 Decorin chr12 GO:1902533 Not Cancer Driver No 96 0.267 81 26 0.321 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:1902533 Census Yes 29 0.172 160 27 0.169 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:1902533 Census Yes 74 0.121 225 23 0.102 0
DDX60 DDX60 Q8IY21 Probable ATP-dependent RNA helicase DDX60 chr4 GO:1902533 Not Cancer Driver No 224 0.131 131 12 0.092 0
DHX58 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 GO:1902533 Not Cancer Driver No 62 0.091 84 8 0.095 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:1902533 Not Cancer Driver No 58 0.218 47 8 0.17 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 GO:1902533 Not Cancer Driver No 230 0.12 1119 135 0.121 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:1902533 Not Cancer Driver No 67 0.091 212 23 0.108 7
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:1902533 Not Cancer Driver No 34 0.157 15 5 0.333 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:1902533 Not Cancer Driver No 96 0.13 514 64 0.125 0
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 GO:1902533 Not Cancer Driver No 97 0.135 437 58 0.133 0
DYNC1LI1 DYNC1LI1 Q9Y6G9 Cytoplasmic dynein 1 light intermediate chain 1 chr3 GO:1902533 Not Cancer Driver No 46 0.088 208 20 0.096 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:1902533 Not Cancer Driver No 37 0.175 97 20 0.206 3
EEF1E1 EEF1E1 O43324 Eukaryotic translation elongation factor 1 epsilon-1 chr6 GO:1902533 Not Cancer Driver No 27 0.155 11 1 0.091 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:1902533 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:1902533 Census, Compendium Yes 444 0.367 223 35 0.157 1
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 GO:1902533 Not Cancer Driver No 37 0.24 21 5 0.238 5
EMC10 EMC10 Q5UCC4 ER membrane protein complex subunit 10 chr19 GO:1902533 Not Cancer Driver No 25 0.095 109 15 0.138 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:1902533 Not Cancer Driver No 182 0.185 140 24 0.171 0
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:1902533 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:1902533 Census, Compendium Yes 428 0.327 323 116 0.359 2
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:1902533 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:1902533 Not Cancer Driver No 192 0.207 213 45 0.211 0
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:1902533 Not Cancer Driver No 47 0.157 72 15 0.208 0
F2 F2 P00734 Prothrombin chr11 GO:1902533 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:1902533 Not Cancer Driver No 73 0.172 19 2 0.105 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:1902533 Not Cancer Driver No 55 0.139 7 2 0.286 0
F2RL2 F2RL2 O00254 Proteinase-activated receptor 3 chr5 GO:1902533 Not Cancer Driver No 54 0.144 0 0 0.0 0
F2RL3 F2RL3 Q96RI0 Proteinase-activated receptor 4 chr19 GO:1902533 Not Cancer Driver No 43 0.112 46 4 0.087 0
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:1902533 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:1902533 Census, Compendium Yes 322 0.455 230 38 0.165 0
FFAR4_ENST00000371481 FFAR4 Q5NUL3 Free fatty acid receptor 4 chr10 GO:1902533 Not Cancer Driver No 47 0.13 0 0 0.0 0
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:1902533 Not Cancer Driver No 113 0.173 158 26 0.165 0
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:1902533 Not Cancer Driver No 30 0.194 29 2 0.069 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:1902533 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:1902533 Not Cancer Driver No 84 0.335 97 51 0.526 7
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:1902533 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:1902533 Census, Compendium Yes 152 0.185 230 43 0.187 74
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:1902533 Not Cancer Driver No 85 0.161 52 8 0.154 0
FIS1 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 GO:1902533 Not Cancer Driver No 25 0.164 6 0 0.0 0
FLCN FLCN Q8NFG4 Folliculin chr17 GO:1902533 Census, Compendium Yes 59 0.102 157 19 0.121 5
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:1902533 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:1902533 Census, Compendium Yes 200 0.201 64 27 0.422 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:1902533 Census, Compendium Yes 253 0.186 259 41 0.158 13
FN1 FN1 P02751 Fibronectin chr2 GO:1902533 Compendium Yes 394 0.159 1243 185 0.149 8
FRMD1 FRMD1 Q8N878 FERM domain-containing protein 1 chr6 GO:1902533 Not Cancer Driver No 82 0.149 259 36 0.139 0
FRMD7 FRMD7 Q6ZUT3 FERM domain-containing protein 7 chrX GO:1902533 Not Cancer Driver No 147 0.206 256 59 0.23 25
FSHR FSHR P23945 Follicle-stimulating hormone receptor chr2 GO:1902533 Not Cancer Driver No 226 0.325 28 11 0.393 16
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:1902533 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:1902533 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:1902533 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:1902533 Not Cancer Driver No 72 0.104 146 3 0.021 0
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:1902533 Not Cancer Driver No 10 0.061 39 5 0.128 0
GADD45B GADD45B O75293 Growth arrest and DNA damage-inducible protein GADD45 beta chr19 GO:1902533 Not Cancer Driver No 9 0.056 14 0 0.0 0
GADD45G GADD45G O95257 Growth arrest and DNA damage-inducible protein GADD45 gamma chr9 GO:1902533 Not Cancer Driver No 13 0.082 20 2 0.1 0
GDF6 GDF6 Q6KF10 Growth/differentiation factor 6 chr8 GO:1902533 Not Cancer Driver No 91 0.2 225 46 0.204 14
GEN1_ENST00000381254 GEN1 Q17RS7 Flap endonuclease GEN homolog 1 chr2 GO:1902533 Not Cancer Driver No 109 0.12 339 52 0.153 0
GH1 GH1 P01241 Somatotropin chr17 GO:1902533 Not Cancer Driver No 54 0.249 24 9 0.375 15
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:1902533 Not Cancer Driver No 35 0.229 68 16 0.235 0
GIPR GIPR P48546 Gastric inhibitory polypeptide receptor chr19 GO:1902533 Not Cancer Driver No 45 0.097 41 0 0.0 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:1902533 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPR137B GPR137B O60478 Integral membrane protein GPR137B chr1 GO:1902533 Not Cancer Driver No 49 0.123 47 1 0.021 0
GPR137C GPR137C Q8N3F9 Integral membrane protein GPR137C chr14 GO:1902533 Not Cancer Driver No 41 0.096 47 0 0.0 0
GPR137_ENST00000313074 GPR137 Q96N19 Integral membrane protein GPR137 chr11 GO:1902533 Not Cancer Driver No 66 0.158 41 11 0.268 0
GPR17 GPR17 Q13304 Uracil nucleotide/cysteinyl leukotriene receptor chr2 GO:1902533 Not Cancer Driver No 57 0.155 16 4 0.25 0
GPR174_ENST00000276077 GPR174 Q9BXC1 Probable G-protein coupled receptor 174 chrX GO:1902533 Not Cancer Driver No 115 0.345 0 0 0.0 0
GPR18_ENST00000397470 GPR18 Q14330 N-arachidonyl glycine receptor chr13 GO:1902533 Not Cancer Driver No 36 0.109 0 0 0.0 0
GPR20 GPR20 Q99678 G-protein coupled receptor 20 chr8 GO:1902533 Not Cancer Driver No 77 0.215 44 11 0.25 0
GPR3 GPR3 P46089 G-protein coupled receptor 3 chr1 GO:1902533 Not Cancer Driver No 38 0.115 13 1 0.077 0
GPR35_ENST00000403859 GPR35 Q9HC97 G-protein coupled receptor 35 chr2 GO:1902533 Not Cancer Driver No 57 0.184 0 0 0.0 0
GPR4 GPR4 P46093 G-protein coupled receptor 4 chr19 GO:1902533 Not Cancer Driver No 57 0.157 44 8 0.182 0
GPR55 GPR55 Q9Y2T6 G-protein coupled receptor 55 chr2 GO:1902533 Not Cancer Driver No 64 0.201 0 0 0.0 0
GPR61_ENST00000618721 GPR61 Q9BZJ8 G-protein coupled receptor 61 chr1 GO:1902533 Not Cancer Driver No 72 0.16 103 23 0.223 0
GPR62 GPR62 Q9BZJ7 G-protein coupled receptor 62 chr3 GO:1902533 Not Cancer Driver No 20 0.054 52 9 0.173 0
GPR65 GPR65 Q8IYL9 Psychosine receptor chr14 GO:1902533 Not Cancer Driver No 70 0.208 0 0 0.0 0
GSDME_ENST00000409775 GSDME O60443 Gasdermin-E chr7 GO:1902533 Not Cancer Driver No 81 0.163 14 3 0.214 0
GUCA1A GUCA1A P43080 Guanylyl cyclase-activating protein 1 chr6 GO:1902533 Not Cancer Driver No 39 0.194 20 4 0.2 17
GUCY1A1_ENST00000513574 GUCY1A1 Q02108 Guanylate cyclase soluble subunit alpha-1 chr4 GO:1902533 Not Cancer Driver No 181 0.262 54 8 0.148 0
GUCY1A2_ENST00000526355 GUCY1A2 P33402 Guanylate cyclase soluble subunit alpha-2 chr11 GO:1902533 Not Cancer Driver No 191 0.261 187 48 0.257 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:1902533 Not Cancer Driver No 47 0.217 124 29 0.234 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:1902533 Not Cancer Driver No 44 0.158 219 32 0.146 2
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:1902533 Not Cancer Driver No 103 0.212 446 94 0.211 0
HCST HCST Q9UBK5 Hematopoietic cell signal transducer chr19 GO:1902533 Not Cancer Driver No 6 0.065 12 0 0.0 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 GO:1902533 Not Cancer Driver No 40 0.111 352 40 0.114 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:1902533 Compendium Yes 233 0.32 43 16 0.372 0
HIC1 HIC1 Q14526 Hypermethylated in cancer 1 protein chr17 GO:1902533 Not Cancer Driver No 24 0.033 361 6 0.017 0
HINT1 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 GO:1902533 Not Cancer Driver No 11 0.087 6 0 0.0 6
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:1902533 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:1902533 Not Cancer Driver No 15 0.023 200 5 0.025 0
IAPP_ENST00000539393 IAPP P10997 Islet amyloid polypeptide chr12 GO:1902533 Not Cancer Driver No 22 0.247 10 2 0.2 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:1902533 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:1902533 Not Cancer Driver No 45 0.231 87 23 0.264 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:1902533 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL19_ENST00000270218 IL19 Q9UHD0 Interleukin-19 chr1 GO:1902533 Not Cancer Driver No 16 0.09 0 0 0.0 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:1902533 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL20RA IL20RA Q9UHF4 Interleukin-20 receptor subunit alpha chr6 GO:1902533 Not Cancer Driver No 72 0.13 231 29 0.126 0
ING4 ING4 Q9UNL4 Inhibitor of growth protein 4 chr12 GO:1902533 Not Cancer Driver No 31 0.124 108 15 0.139 0
INS INS P01308 Insulin chr11 GO:1902533 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSL3_ENST00000317306 INSL3 P51460 Insulin-like 3 chr19 GO:1902533 Not Cancer Driver No 18 0.137 34 12 0.353 3
INSR INSR P06213 Insulin receptor chr19 GO:1902533 Not Cancer Driver No 190 0.137 280 57 0.204 64
IQCJ-SCHIP1 IQCJ-SCHIP1 B3KU38 IQCJ-SCHIP1 readthrough transcript protein chr3 GO:1902533 Not Cancer Driver No 76 0.135 517 71 0.137 0
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:1902533 Census Yes 153 0.146 92 9 0.098 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:1902533 Census, Compendium Yes 136 0.12 59 5 0.085 5
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:1902533 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:1902533 Census, Compendium Yes 226 0.232 83 33 0.398 21
KL KL Q9UEF7 Klotho chr13 GO:1902533 Not Cancer Driver No 175 0.173 104 5 0.048 1
KLB KLB Q86Z14 Beta-klotho chr4 GO:1902533 Not Cancer Driver No 139 0.133 6 1 0.167 0
KLHL22 KLHL22 Q53GT1 Kelch-like protein 22 chr22 GO:1902533 Not Cancer Driver No 90 0.142 50 8 0.16 0
KRAS KRAS P01116 GTPase KRas chr12 GO:1902533 Census, Compendium Yes 788 4.169 7 2 0.286 27
LACRT LACRT Q9GZZ8 Extracellular glycoprotein lacritin chr12 GO:1902533 Not Cancer Driver No 38 0.275 90 27 0.3 0
LAMTOR5_ENST00000602318 LAMTOR5 O43504 Ragulator complex protein LAMTOR5 chr1 GO:1902533 Not Cancer Driver No 10 0.11 17 0 0.0 0
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:1902533 Not Cancer Driver No 133 0.113 97 10 0.103 1
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:1902533 Census Yes 86 0.169 94 13 0.138 1
LEP LEP P41159 Leptin chr7 GO:1902533 Not Cancer Driver No 29 0.174 0 0 0.0 2
LMCD1 LMCD1 Q9NZU5 LIM and cysteine-rich domains protein 1 chr3 GO:1902533 Not Cancer Driver No 63 0.173 110 24 0.218 0
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 GO:1902533 Not Cancer Driver No 79 0.217 21 6 0.286 0
LPAR4 LPAR4 Q99677 Lysophosphatidic acid receptor 4 chrX GO:1902533 Compendium Yes 123 0.332 10 3 0.3 0
LPAR6_ENST00000620633 LPAR6 P43657 Lysophosphatidic acid receptor 6 chr13 GO:1902533 Not Cancer Driver No 39 0.113 0 0 0.0 3
LRRK1 LRRK1 Q38SD2 Leucine-rich repeat serine/threonine-protein kinase 1 chr15 GO:1902533 Not Cancer Driver No 289 0.143 261 33 0.126 0
MAD1L1_ENST00000399654 MAD1L1 Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 chr7 GO:1902533 Not Cancer Driver No 117 0.163 526 77 0.146 0
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 GO:1902533 Not Cancer Driver No 26 0.127 12 1 0.083 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:1902533 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:1902533 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:1902533 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:1902533 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:1902533 Census Yes 157 0.163 593 91 0.153 0
MAP3K20 MAP3K20 Q9NYL2 Mitogen-activated protein kinase kinase kinase 20 chr2 GO:1902533 Not Cancer Driver No 101 0.126 294 41 0.139 1
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 GO:1902533 Not Cancer Driver No 74 0.118 355 44 0.124 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:1902533 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:1902533 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:1902533 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:1902533 Not Cancer Driver No 78 0.095 243 23 0.095 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 GO:1902533 Not Cancer Driver No 143 0.115 649 55 0.085 0
MAPRE2 MAPRE2 Q15555 Microtubule-associated protein RP/EB family member 2 chr18 GO:1902533 Not Cancer Driver No 50 0.153 176 28 0.159 3
MAZ_ENST00000322945 MAZ P56270 Myc-associated zinc finger protein chr16 GO:1902533 Not Cancer Driver No 46 0.096 249 22 0.088 0
MC1R_ENST00000639847 MC1R Q01726 Melanocyte-stimulating hormone receptor chr16 GO:1902533 Not Cancer Driver No 39 0.123 0 0 0.0 5
MCF2L_ENST00000375608 MCF2L O15068 Guanine nucleotide exchange factor DBS chr13 GO:1902533 Not Cancer Driver No 173 0.152 410 54 0.132 0
MCL1 MCL1 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 chr1 GO:1902533 Not Cancer Driver No 30 0.086 203 21 0.103 0
MFHAS1 MFHAS1 Q9Y4C4 Malignant fibrous histiocytoma-amplified sequence 1 chr8 GO:1902533 Not Cancer Driver No 95 0.09 98 9 0.092 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:1902533 Not Cancer Driver No 4 0.035 0 0 0.0 0
MINK1 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 GO:1902533 Not Cancer Driver No 113 0.085 740 56 0.076 0
MIOS_ENST00000405785 MIOS Q9NXC5 GATOR complex protein MIOS chr7 GO:1902533 Not Cancer Driver No 98 0.112 72 4 0.056 0
MSX1 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:1902533 Not Cancer Driver No 39 0.129 197 16 0.081 7
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:1902533 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYDGF MYDGF Q969H8 Myeloid-derived growth factor chr19 GO:1902533 Not Cancer Driver No 23 0.133 26 4 0.154 0
MYOC MYOC Q99972 Myocilin chr1 GO:1902533 Not Cancer Driver No 92 0.183 196 43 0.219 58
NACC2_ENST00000371753 NACC2 Q96BF6 Nucleus accumbens-associated protein 2 chr9 GO:1902533 Not Cancer Driver No 24 0.041 238 10 0.042 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:1902533 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:1902533 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:1902533 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:1902533 Not Cancer Driver No 247 0.219 51 10 0.196 4
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 GO:1902533 Not Cancer Driver No 80 0.125 313 45 0.144 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:1902533 Not Cancer Driver No 150 0.114 711 79 0.111 0
NET1 NET1 Q7Z628 Neuroepithelial cell-transforming gene 1 protein chr10 GO:1902533 Not Cancer Driver No 60 0.101 294 37 0.126 0
NEUROD2 NEUROD2 Q15784 Neurogenic differentiation factor 2 chr17 GO:1902533 Not Cancer Driver No 26 0.068 210 14 0.067 2
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:1902533 Not Cancer Driver No 35 0.15 171 16 0.094 0
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:1902533 Not Cancer Driver No 214 0.248 248 61 0.246 4
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 GO:1902533 Not Cancer Driver No 94 0.186 255 53 0.208 1
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:1902533 Not Cancer Driver No 101 0.179 18 8 0.444 0
NPPC NPPC P23582 C-type natriuretic peptide chr2 GO:1902533 Not Cancer Driver No 10 0.079 82 6 0.073 0
NPR1 NPR1 P16066 Atrial natriuretic peptide receptor 1 chr1 GO:1902533 Not Cancer Driver No 141 0.133 78 16 0.205 0
NPR2 NPR2 P20594 Atrial natriuretic peptide receptor 2 chr9 GO:1902533 Not Cancer Driver No 144 0.138 89 18 0.202 20
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:1902533 Census, Compendium Yes 159 0.248 528 132 0.25 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:1902533 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:1902533 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:1902533 Census, Compendium Yes 249 0.297 57 21 0.368 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:1902533 Not Cancer Driver No 10 0.122 82 10 0.122 0
OASL OASL Q15646 2'-5'-oligoadenylate synthase-like protein chr12 GO:1902533 Not Cancer Driver No 76 0.148 8 4 0.5 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:1902533 Not Cancer Driver No 117 0.308 18 5 0.278 0
OR51E2_ENST00000641638 OR51E2 Q9H255 Olfactory receptor 51E2 chr11 GO:1902533 Not Cancer Driver No 108 0.338 0 0 0.0 0
OSM OSM P13725 Oncostatin-M chr22 GO:1902533 Not Cancer Driver No 43 0.171 114 24 0.211 0
OTUD5 OTUD5 Q96G74 OTU domain-containing protein 5 chrX GO:1902533 Not Cancer Driver No 55 0.096 430 39 0.091 4
P2RX2_ENST00000643471 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 GO:1902533 Not Cancer Driver No 62 0.132 104 13 0.125 2
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:1902533 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:1902533 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX5 P2RX5 Q93086 P2X purinoceptor 5 chr17 GO:1902533 Not Cancer Driver No 58 0.137 73 14 0.192 0
P2RY10 P2RY10 O00398 Putative P2Y purinoceptor 10 chrX GO:1902533 Not Cancer Driver No 113 0.333 0 0 0.0 0
P2RY8 P2RY8 Q86VZ1 P2Y purinoceptor 8 chrX GO:1902533 Census, Compendium Yes 126 0.351 23 5 0.217 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:1902533 Not Cancer Driver No 57 0.105 299 30 0.1 2
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:1902533 Not Cancer Driver No 11 0.058 30 0 0.0 5
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:1902533 Not Cancer Driver No 46 0.115 13 5 0.385 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:1902533 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:1902533 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:1902533 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:1902533 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:1902533 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:1902533 Census, Compendium Yes 164 0.148 231 44 0.19 7
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 GO:1902533 Not Cancer Driver No 58 0.114 142 23 0.162 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:1902533 Not Cancer Driver No 30 0.103 157 13 0.083 0
PIK3AP1 PIK3AP1 Q6ZUJ8 Phosphoinositide 3-kinase adapter protein 1 chr10 GO:1902533 Not Cancer Driver No 141 0.175 406 81 0.2 0
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:1902533 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:1902533 Not Cancer Driver No 318 0.289 121 39 0.322 0
PIP4P1_ENST00000250489 PIP4P1 Q86T03 Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase chr14 GO:1902533 Not Cancer Driver No 36 0.13 78 4 0.051 0
PJA2 PJA2 O43164 E3 ubiquitin-protein ligase Praja-2 chr5 GO:1902533 Not Cancer Driver No 80 0.113 598 66 0.11 0
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:1902533 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLA2R1 PLA2R1 Q13018 Secretory phospholipase A2 receptor chr2 GO:1902533 Not Cancer Driver No 202 0.138 39 2 0.051 0
PLAGL2 PLAGL2 Q9UPG8 Zinc finger protein PLAGL2 chr20 GO:1902533 Not Cancer Driver No 62 0.125 204 29 0.142 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:1902533 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLEKHF1 PLEKHF1 Q96S99 Pleckstrin homology domain-containing family F member 1 chr19 GO:1902533 Not Cancer Driver No 30 0.108 65 10 0.154 0
PLXNB1_ENST00000296440 PLXNB1 O43157 Plexin-B1 chr3 GO:1902533 Not Cancer Driver No 228 0.107 684 67 0.098 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:1902533 Not Cancer Driver No 2 0.037 23 1 0.043 0
PML PML P29590 Protein PML chr15 GO:1902533 Census, Compendium Yes 112 0.127 312 34 0.109 0
POMC POMC P01189 Pro-opiomelanocortin chr2 GO:1902533 Not Cancer Driver No 50 0.187 198 38 0.192 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:1902533 Not Cancer Driver No 72 0.163 69 7 0.101 0
PRAG1_ENST00000622241 PRAG1 Q86YV5 Inactive tyrosine-protein kinase PRAG1 chr8 GO:1902533 Not Cancer Driver No 193 0.137 988 150 0.152 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:1902533 Compendium Yes 118 0.134 246 34 0.138 0
PRKRA PRKRA O75569 Interferon-inducible double-stranded RNA-dependent protein kinase activator A chr2 GO:1902533 Not Cancer Driver No 41 0.131 104 12 0.115 1
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:1902533 Not Cancer Driver No 50 0.135 18 1 0.056 0
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:1902533 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRR5L PRR5L Q6MZQ0 Proline-rich protein 5-like chr11 GO:1902533 Not Cancer Driver No 57 0.155 108 12 0.111 0
PRR5_ENST00000336985 PRR5 P85299 Proline-rich protein 5 chr22 GO:1902533 Not Cancer Driver No 50 0.129 173 22 0.127 0
PTBP1_ENST00000349038 PTBP1 P26599 Polypyrimidine tract-binding protein 1 chr19 GO:1902533 Not Cancer Driver No 74 0.139 154 17 0.11 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:1902533 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:1902533 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:1902533 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:1902533 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:1902533 Census, Compendium Yes 73 0.123 192 25 0.13 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 GO:1902533 Not Cancer Driver No 150 0.126 640 77 0.12 3
PUM2_ENST00000403432 PUM2 Q8TB72 Pumilio homolog 2 chr2 GO:1902533 Not Cancer Driver No 132 0.124 575 83 0.144 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 GO:1902533 Not Cancer Driver No 174 0.354 291 99 0.34 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:1902533 Census, Compendium Yes 66 0.344 2 1 0.5 6
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:1902533 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAD9A RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:1902533 Not Cancer Driver No 34 0.087 135 7 0.052 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:1902533 Not Cancer Driver No 30 0.203 0 0 0.0 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:1902533 Not Cancer Driver No 216 0.144 803 116 0.144 0
RELL1_ENST00000314117 RELL1 Q8IUW5 RELT-like protein 1 chr4 GO:1902533 Not Cancer Driver No 19 0.07 201 11 0.055 0
RELL2 RELL2 Q8NC24 RELT-like protein 2 chr5 GO:1902533 Not Cancer Driver No 39 0.129 259 37 0.143 0
RELN RELN P78509 Reelin chr7 GO:1902533 Not Cancer Driver No 761 0.22 107 19 0.178 7
RGL2 RGL2 O15211 Ral guanine nucleotide dissociation stimulator-like 2 chr6 GO:1902533 Not Cancer Driver No 87 0.112 461 51 0.111 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:1902533 Not Cancer Driver No 66 0.127 295 39 0.132 0
RNF183_ENST00000297894 RNF183 Q96D59 E3 ubiquitin-protein ligase RNF183 chr9 GO:1902533 Not Cancer Driver No 22 0.115 29 1 0.034 0
ROBO1 ROBO1 Q9Y6N7 Roundabout homolog 1 chr3 GO:1902533 Not Cancer Driver No 353 0.214 1122 234 0.209 0
ROR1 ROR1 Q01973 Inactive tyrosine-protein kinase transmembrane receptor ROR1 chr1 GO:1902533 Not Cancer Driver No 144 0.154 280 43 0.154 1
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:1902533 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 GO:1902533 Not Cancer Driver No 14 0.1 29 4 0.138 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:1902533 Not Cancer Driver No 16 0.11 114 13 0.114 0
RPL37 RPL37 P61927 60S ribosomal protein L37 chr5 GO:1902533 Not Cancer Driver No 12 0.124 83 10 0.12 0
RPS15_ENST00000592588 RPS15 P62841 40S ribosomal protein S15 chr19 GO:1902533 Not Cancer Driver No 13 0.09 59 7 0.119 0
RPS20_ENST00000521262 RPS20 P60866 40S ribosomal protein S20 chr8 GO:1902533 Not Cancer Driver No 18 0.151 53 8 0.151 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:1902533 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 GO:1902533 Not Cancer Driver No 29 0.149 39 7 0.179 0
RRAGA RRAGA Q7L523 Ras-related GTP-binding protein A chr9 GO:1902533 Not Cancer Driver No 30 0.096 0 0 0.0 0
RRAGB RRAGB Q5VZM2 Ras-related GTP-binding protein B chrX GO:1902533 Not Cancer Driver No 67 0.179 37 5 0.135 0
RRAGD RRAGD Q9NQL2 Ras-related GTP-binding protein D chr6 GO:1902533 Not Cancer Driver No 42 0.105 83 5 0.06 0
RTN4R RTN4R Q9BZR6 Reticulon-4 receptor chr22 GO:1902533 Not Cancer Driver No 38 0.08 148 17 0.115 5
RUNDC3A RUNDC3A Q59EK9 RUN domain-containing protein 3A chr17 GO:1902533 Not Cancer Driver No 39 0.087 175 8 0.046 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 GO:1902533 Not Cancer Driver No 22 0.237 8 4 0.5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:1902533 Not Cancer Driver No 18 0.158 76 7 0.092 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:1902533 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SCT SCT P09683 Secretin chr11 GO:1902533 Not Cancer Driver No 4 0.033 71 3 0.042 0
SCTR SCTR P47872 Secretin receptor chr2 GO:1902533 Not Cancer Driver No 74 0.168 18 1 0.056 0
SEH1L_ENST00000262124 SEH1L Q96EE3 Nucleoporin SEH1 chr18 GO:1902533 Not Cancer Driver No 40 0.111 71 11 0.155 0
SELP SELP P16109 P-selectin chr1 GO:1902533 Not Cancer Driver No 226 0.272 14 2 0.143 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:1902533 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEPT4_ENST00000317268 SEPTIN4 O43236 Septin-4 chr17 GO:1902533 Not Cancer Driver No 61 0.128 220 31 0.141 0
SERINC3_ENST00000255175 SERINC3 Q13530 Serine incorporator 3 chr20 GO:1902533 Not Cancer Driver No 73 0.154 38 9 0.237 0
SERPINA12 SERPINA12 Q8IW75 Serpin A12 chr14 GO:1902533 Not Cancer Driver No 90 0.217 22 3 0.136 0
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 GO:1902533 Census Yes 59 0.083 595 48 0.081 0
SIAH1_ENST00000394725 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 GO:1902533 Not Cancer Driver No 35 0.124 28 2 0.071 5
SIK3 SIK3 Q9Y2K2 Serine/threonine-protein kinase SIK3 chr11 GO:1902533 Not Cancer Driver No 143 0.108 964 107 0.111 1
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:1902533 Not Cancer Driver No 70 0.094 435 31 0.071 0
SKIL_ENST00000259119 SKIL P12757 Ski-like protein chr3 GO:1902533 Not Cancer Driver No 77 0.113 356 32 0.09 0
SLC15A3 SLC15A3 Q8IY34 Solute carrier family 15 member 3 chr11 GO:1902533 Not Cancer Driver No 63 0.108 43 1 0.023 0
SLC15A4 SLC15A4 Q8N697 Solute carrier family 15 member 4 chr12 GO:1902533 Not Cancer Driver No 66 0.114 23 4 0.174 0
SLC46A2 SLC46A2 Q9BY10 Thymic stromal cotransporter homolog chr9 GO:1902533 Not Cancer Driver No 45 0.095 36 3 0.083 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:1902533 Not Cancer Driver No 89 0.109 251 29 0.116 1
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:1902533 Not Cancer Driver No 19 0.053 318 16 0.05 4
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:1902533 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:1902533 Compendium Yes 197 0.148 458 62 0.135 38
SOS2 SOS2 Q07890 Son of sevenless homolog 2 chr14 GO:1902533 Not Cancer Driver No 173 0.13 362 54 0.149 2
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:1902533 Not Cancer Driver No 61 0.138 368 53 0.144 2
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:1902533 Compendium Yes 86 0.169 495 82 0.166 18
SPATC1L SPATC1L Q9H0A9 Speriolin-like protein chr21 GO:1902533 Not Cancer Driver No 30 0.088 179 11 0.061 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:1902533 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:1902533 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:1902533 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPPL3 SPPL3 Q8TCT6 Signal peptide peptidase-like 3 chr12 GO:1902533 Not Cancer Driver No 45 0.117 23 0 0.0 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:1902533 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 GO:1902533 Not Cancer Driver No 73 0.175 228 43 0.189 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:1902533 Census Yes 53 0.099 130 11 0.085 1
STIMATE STIMATE Q86TL2 Store-operated calcium entry regulator STIMATE chr3 GO:1902533 Not Cancer Driver No 27 0.092 61 4 0.066 0
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:1902533 Not Cancer Driver No 64 0.117 182 19 0.104 0
STYXL1_ENST00000359697 STYXL1 Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 chr7 GO:1902533 Not Cancer Driver No 55 0.176 18 3 0.167 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:1902533 Census Yes 96 0.151 131 27 0.206 5
SYNPO2L SYNPO2L Q9H987 Synaptopodin 2-like protein chr10 GO:1902533 Not Cancer Driver No 103 0.105 950 99 0.104 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:1902533 Not Cancer Driver No 123 0.137 494 64 0.13 0
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:1902533 Not Cancer Driver No 21 0.198 33 7 0.212 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:1902533 Not Cancer Driver No 219 0.195 126 22 0.175 10
TELO2 TELO2 Q9Y4R8 Telomere length regulation protein TEL2 homolog chr16 GO:1902533 Not Cancer Driver No 113 0.135 154 23 0.149 5
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:1902533 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGM2 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 GO:1902533 Not Cancer Driver No 123 0.179 107 26 0.243 0
TIAL1_ENST00000436547 TIAL1 Q01085 Nucleolysin TIAR chr10 GO:1902533 Not Cancer Driver No 45 0.12 122 12 0.098 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:1902533 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:1902533 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:1902533 Not Cancer Driver No 141 0.137 35 3 0.086 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:1902533 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:1902533 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:1902533 Not Cancer Driver No 52 0.164 56 1 0.018 1
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:1902533 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPR TPR P12270 Nucleoprotein TPR chr1 GO:1902533 Census Yes 311 0.132 1990 266 0.134 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:1902533 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:1902533 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRAT1 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 GO:1902533 Not Cancer Driver No 86 0.462 129 67 0.519 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:1902533 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIM15 TRIM15 Q9C019 Tripartite motif-containing protein 15 chr6 GO:1902533 Not Cancer Driver No 69 0.148 79 11 0.139 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 GO:1902533 Not Cancer Driver No 20 0.087 102 8 0.078 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 GO:1902533 Not Cancer Driver No 25 0.164 24 3 0.125 0
UBE2V1_ENST00000371674 UBE2V1 Q13404 Ubiquitin-conjugating enzyme E2 variant 1 chr20 GO:1902533 Not Cancer Driver No 19 0.129 51 5 0.098 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:1902533 Not Cancer Driver No 141 0.161 136 22 0.162 0
UCN UCN P55089 Urocortin chr2 GO:1902533 Not Cancer Driver No 7 0.056 61 4 0.066 0
UNC5B UNC5B Q8IZJ1 Netrin receptor UNC5B chr10 GO:1902533 Not Cancer Driver No 155 0.164 117 20 0.171 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 GO:1902533 Not Cancer Driver No 136 0.139 259 39 0.151 0
USP17L2 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 GO:1902533 Not Cancer Driver No 105 0.198 201 54 0.269 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:1902533 Not Cancer Driver No 27 0.116 41 7 0.171 0
VWF VWF P04275 von Willebrand factor chr12 GO:1902533 Not Cancer Driver No 456 0.162 91 16 0.176 43
WAC WAC Q9BTA9 WW domain-containing adapter protein with coiled-coil chr10 GO:1902533 Not Cancer Driver No 106 0.164 571 95 0.166 0
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:1902533 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT16 WNT16 Q9UBV4 Protein Wnt-16 chr7 GO:1902533 Not Cancer Driver No 59 0.162 28 9 0.321 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:1902533 Not Cancer Driver No 66 0.174 0 0 0.0 2
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:1902533 Not Cancer Driver No 279 0.209 134 24 0.179 1
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 GO:1902533 Not Cancer Driver No 24 0.069 35 2 0.057 1
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:1902533 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:1902533 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZCCHC3 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 GO:1902533 Not Cancer Driver No 28 0.069 160 1 0.006 0
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:1902533 Not Cancer Driver No 43 0.111 312 34 0.109 0