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Total number of protein in "GO:1902531" GO term:  839

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:1902531 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:1902531 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABL2 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:1902531 Census, Compendium Yes 171 0.145 641 70 0.109 0
ABRA ABRA Q8N0Z2 Actin-binding Rho-activating protein chr8 GO:1902531 Not Cancer Driver No 108 0.283 285 86 0.302 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:1902531 Not Cancer Driver No 104 0.129 68 5 0.074 0
ACKR3 ACKR3 P25106 Atypical chemokine receptor 3 chr2 GO:1902531 Census, Compendium Yes 78 0.215 0 0 0.0 1
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:1902531 Not Cancer Driver No 123 0.137 135 13 0.096 0
ADA ADA P00813 Adenosine deaminase chr20 GO:1902531 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADCYAP1R1_ENST00000304166 ADCYAP1R1 P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor chr7 GO:1902531 Not Cancer Driver No 127 0.271 0 0 0.0 0
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 GO:1902531 Not Cancer Driver No 64 0.092 67 4 0.06 9
ADGRG3 ADGRG3 Q86Y34 Adhesion G protein-coupled receptor G3 chr16 GO:1902531 Not Cancer Driver No 87 0.158 42 5 0.119 0
ADGRV1_ENST00000645211 ADGRV1 Q8WXG9 Adhesion G-protein coupled receptor V1 chr5 GO:1902531 Not Cancer Driver No 1124 0.178 496 77 0.155 2
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:1902531 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADIPOR1 ADIPOR1 Q96A54 Adiponectin receptor protein 1 chr1 GO:1902531 Not Cancer Driver No 63 0.168 69 10 0.145 0
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:1902531 Not Cancer Driver No 23 0.069 0 0 0.0 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:1902531 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:1902531 Not Cancer Driver No 52 0.126 35 4 0.114 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:1902531 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGT AGT P01019 Angiotensinogen chr1 GO:1902531 Not Cancer Driver No 85 0.179 33 10 0.303 1
AIDA AIDA Q96BJ3 Axin interactor, dorsalization-associated protein chr1 GO:1902531 Not Cancer Driver No 36 0.118 87 9 0.103 0
AIP AIP O00170 AH receptor-interacting protein chr11 GO:1902531 Not Cancer Driver No 32 0.097 64 9 0.141 1
AJUBA AJUBA Q96IF1 LIM domain-containing protein ajuba chr14 GO:1902531 Compendium Yes 45 0.084 307 13 0.042 0
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 GO:1902531 Not Cancer Driver No 215 0.121 1770 214 0.121 0
AKAP13_ENST00000394518 AKAP13 Q12802 A-kinase anchor protein 13 chr15 GO:1902531 Not Cancer Driver No 359 0.128 2091 258 0.123 0
AKAP5_ENST00000320636 AKAP5 P24588 A-kinase anchor protein 5 chr14 GO:1902531 Not Cancer Driver No 37 0.087 405 34 0.084 0
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:1902531 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AKAP7 AKAP7 Q9P0M2 A-kinase anchor protein 7 isoform gamma chr6 GO:1902531 Not Cancer Driver No 38 0.109 122 18 0.148 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:1902531 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALKAL1 ALKAL1 Q6UXT8 ALK and LTK ligand 1 chr8 GO:1902531 Not Cancer Driver No 18 0.14 49 3 0.061 0
ALKAL2 ALKAL2 Q6UX46 ALK and LTK ligand 2 chr2 GO:1902531 Not Cancer Driver No 7 0.046 31 0 0.0 0
ALS2 ALS2 Q96Q42 Alsin chr2 GO:1902531 Not Cancer Driver No 194 0.117 353 36 0.102 0
AMBP AMBP P02760 Protein AMBP chr9 GO:1902531 Not Cancer Driver No 57 0.162 61 15 0.246 0
ANAPC15_ENST00000538393 ANAPC15 P60006 Anaphase-promoting complex subunit 15 chr11 GO:1902531 Not Cancer Driver No 15 0.124 117 14 0.12 0
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:1902531 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANKRD1 ANKRD1 Q15327 Ankyrin repeat domain-containing protein 1 chr10 GO:1902531 Not Cancer Driver No 52 0.163 83 13 0.157 0
ANKRD17 ANKRD17 O75179 Ankyrin repeat domain-containing protein 17 chr4 GO:1902531 Not Cancer Driver No 312 0.12 1790 221 0.123 9
ANKRD54 ANKRD54 Q6NXT1 Ankyrin repeat domain-containing protein 54 chr22 GO:1902531 Not Cancer Driver No 26 0.087 188 12 0.064 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:1902531 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOC3 APOC3 P02656 Apolipoprotein C-III chr11 GO:1902531 Not Cancer Driver No 14 0.141 12 2 0.167 1
APOE APOE P02649 Apolipoprotein E chr19 GO:1902531 Not Cancer Driver No 25 0.079 124 6 0.048 12
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 GO:1902531 Not Cancer Driver No 18 0.103 5 0 0.0 0
ARFGAP1_ENST00000370283 ARFGAP1 Q8N6T3 ADP-ribosylation factor GTPase-activating protein 1 chr20 GO:1902531 Not Cancer Driver No 60 0.148 264 37 0.14 0
ARFGEF1 ARFGEF1 Q9Y6D6 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 chr8 GO:1902531 Not Cancer Driver No 243 0.131 456 54 0.118 0
ARFGEF2 ARFGEF2 Q9Y6D5 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 chr20 GO:1902531 Not Cancer Driver No 254 0.142 358 63 0.176 0
ARFGEF3 ARFGEF3 Q5TH69 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 chr6 GO:1902531 Not Cancer Driver No 258 0.119 584 58 0.099 0
ARHGAP17 ARHGAP17 Q68EM7 Rho GTPase-activating protein 17 chr16 GO:1902531 Not Cancer Driver No 123 0.14 547 72 0.132 0
ARHGAP24 ARHGAP24 Q8N264 Rho GTPase-activating protein 24 chr4 GO:1902531 Not Cancer Driver No 103 0.138 482 67 0.139 0
ARHGAP35_ENST00000614079 ARHGAP35 Q9NRY4 Rho GTPase-activating protein 35 chr19 GO:1902531 Census, Compendium Yes 255 0.17 409 58 0.142 0
ARHGAP42 ARHGAP42 A6NI28 Rho GTPase-activating protein 42 chr11 GO:1902531 Not Cancer Driver No 63 0.072 311 17 0.055 0
ARHGAP44 ARHGAP44 Q17R89 Rho GTPase-activating protein 44 chr17 GO:1902531 Not Cancer Driver No 126 0.154 424 67 0.158 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:1902531 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARHGEF3_ENST00000296315 ARHGEF3 Q9NR81 Rho guanine nucleotide exchange factor 3 chr3 GO:1902531 Not Cancer Driver No 70 0.133 154 17 0.11 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:1902531 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARMC10 ARMC10 Q8N2F6 Armadillo repeat-containing protein 10 chr7 GO:1902531 Not Cancer Driver No 39 0.114 58 4 0.069 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 GO:1902531 Not Cancer Driver No 49 0.117 154 13 0.084 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:1902531 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:1902531 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:1902531 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:1902531 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:1902531 Census, Compendium Yes 338 0.128 106 14 0.132 1
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 GO:1902531 Not Cancer Driver No 36 0.089 178 21 0.118 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:1902531 Not Cancer Driver No 51 0.148 63 8 0.127 0
AUTS2 AUTS2 Q8WXX7 Autism susceptibility gene 2 protein chr7 GO:1902531 Not Cancer Driver No 219 0.174 1218 213 0.175 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:1902531 Census, Compendium Yes 120 0.139 619 88 0.142 4
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:1902531 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 GO:1902531 Not Cancer Driver No 37 0.083 63 7 0.111 0
BANK1 BANK1 Q8NDB2 B-cell scaffold protein with ankyrin repeats chr4 GO:1902531 Not Cancer Driver No 150 0.191 394 73 0.185 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:1902531 Census Yes 30 0.156 39 2 0.051 0
BBC3 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 GO:1902531 Not Cancer Driver No 20 0.077 253 20 0.079 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:1902531 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:1902531 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:1902531 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:1902531 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:1902531 Census, Compendium Yes 134 0.19 328 67 0.204 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 GO:1902531 Census, Compendium Yes 421 0.458 899 408 0.454 0
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 GO:1902531 Not Cancer Driver No 81 0.207 0 0 0.0 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:1902531 Not Cancer Driver No 45 0.1 190 19 0.1 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 GO:1902531 Not Cancer Driver No 23 0.118 74 9 0.122 0
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 GO:1902531 Not Cancer Driver No 69 0.112 83 9 0.108 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 GO:1902531 Census, Compendium Yes 77 0.127 98 16 0.163 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:1902531 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:1902531 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:1902531 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMT2 BMT2 Q1RMZ1 S-adenosylmethionine sensor upstream of mTORC1 chr7 GO:1902531 Not Cancer Driver No 65 0.16 81 10 0.123 0
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:1902531 Not Cancer Driver No 7 0.033 0 0 0.0 0
BOP1 BOP1 Q14137 Ribosome biogenesis protein BOP1 chr8 GO:1902531 Not Cancer Driver No 20 0.027 304 19 0.062 0
BST1 BST1 Q10588 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 chr4 GO:1902531 Not Cancer Driver No 40 0.126 11 0 0.0 0
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:1902531 Not Cancer Driver No 92 0.176 24 2 0.083 0
C10orf71 CEFIP Q711Q0 Cardiac-enriched FHL2-interacting protein chr10 GO:1902531 Not Cancer Driver No 229 0.16 1356 218 0.161 0
C12orf66_ENST00000398055 KICS2 Q96MD2 KICSTOR subunit 2 chr12 GO:1902531 Not Cancer Driver No 61 0.137 35 6 0.171 0
C16orf72 TAPR1 Q14CZ0 Telomere attrition and p53 response 1 protein chr16 GO:1902531 Not Cancer Driver No 33 0.12 201 21 0.104 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:1902531 Not Cancer Driver No 14 0.05 103 6 0.058 2
C1QL4 C1QL4 Q86Z23 Complement C1q-like protein 4 chr12 GO:1902531 Not Cancer Driver No 19 0.08 101 5 0.05 0
C1QTNF3_ENST00000231338 C1QTNF3 Q9BXJ4 Complement C1q tumor necrosis factor-related protein 3 chr5 GO:1902531 Not Cancer Driver No 42 0.171 73 14 0.192 0
C3orf33 C3orf33 Q6P1S2 Protein C3orf33 chr3 GO:1902531 Not Cancer Driver No 30 0.102 23 0 0.0 0
C9orf72 C9orf72 Q96LT7 Guanine nucleotide exchange factor C9orf72 chr9 GO:1902531 Not Cancer Driver No 64 0.133 11 0 0.0 0
CADM4 CADM4 Q8NFZ8 Cell adhesion molecule 4 chr19 GO:1902531 Not Cancer Driver No 48 0.124 94 9 0.096 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 GO:1902531 Not Cancer Driver No 162 0.342 29 9 0.31 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:1902531 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:1902531 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:1902531 Not Cancer Driver No 17 0.114 115 10 0.087 3
CAMTA1 CAMTA1 Q9Y6Y1 Calmodulin-binding transcription activator 1 chr1 GO:1902531 Census, Compendium Yes 300 0.179 883 152 0.172 0
CASTOR1 CASTOR1 Q8WTX7 Cytosolic arginine sensor for mTORC1 subunit 1 chr22 GO:1902531 Not Cancer Driver No 27 0.082 39 5 0.128 0
CASTOR3 CASTOR3 Q8NAP1 Putative protein CASTOR 3 chr7 GO:1902531 Not Cancer Driver No 18 0.11 1 0 0.0 0
CAT CAT P04040 Catalase chr11 GO:1902531 Not Cancer Driver No 70 0.133 176 18 0.102 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:1902531 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:1902531 Not Cancer Driver No 27 0.179 0 0 0.0 25
CAVIN3 CAVIN3 Q969G5 Caveolae-associated protein 3 chr11 GO:1902531 Not Cancer Driver No 22 0.084 234 19 0.081 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:1902531 Census, Compendium Yes 115 0.127 512 56 0.109 4
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 GO:1902531 Not Cancer Driver No 102 0.111 528 62 0.117 0
CCDC125_ENST00000396499 CCDC125 Q86Z20 Coiled-coil domain-containing protein 125 chr5 GO:1902531 Not Cancer Driver No 58 0.114 261 23 0.088 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:1902531 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:1902531 Not Cancer Driver No 66 0.185 19 1 0.053 0
CCNB1 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 GO:1902531 Not Cancer Driver No 49 0.113 145 14 0.097 0
CD22 CD22 P20273 B-cell receptor CD22 chr19 GO:1902531 Not Cancer Driver No 173 0.204 290 66 0.228 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:1902531 Census Yes 42 0.191 18 10 0.556 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:1902531 Not Cancer Driver No 28 0.135 72 12 0.167 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:1902531 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:1902531 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD44 CD44 P16070 CD44 antigen chr11 GO:1902531 Not Cancer Driver No 75 0.101 542 60 0.111 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:1902531 Census Yes 31 0.105 185 20 0.108 0
CDH13_ENST00000567109 CDH13 P55290 Cadherin-13 chr16 GO:1902531 Not Cancer Driver No 168 0.236 235 59 0.251 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 GO:1902531 Not Cancer Driver No 217 0.115 1136 128 0.113 0
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:1902531 Not Cancer Driver No 50 0.099 99 20 0.202 0
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 GO:1902531 Not Cancer Driver No 17 0.102 44 3 0.068 0
CDT1 CDT1 Q9H211 DNA replication factor Cdt1 chr16 GO:1902531 Not Cancer Driver No 60 0.11 377 35 0.093 5
CHD5 CHD5 Q8TDI0 Chromodomain-helicase-DNA-binding protein 5 chr1 GO:1902531 Not Cancer Driver No 365 0.187 931 183 0.197 0
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:1902531 Not Cancer Driver No 58 0.122 86 16 0.186 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:1902531 Census, Compendium Yes 335 0.617 157 130 0.828 13
CHERP CHERP Q8IWX8 Calcium homeostasis endoplasmic reticulum protein chr19 GO:1902531 Not Cancer Driver No 109 0.119 707 79 0.112 0
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 GO:1902531 Not Cancer Driver No 27 0.138 70 12 0.171 0
CHP2 CHP2 O43745 Calcineurin B homologous protein 2 chr16 GO:1902531 Not Cancer Driver No 43 0.219 65 16 0.246 0
CHRNA10 CHRNA10 Q9GZZ6 Neuronal acetylcholine receptor subunit alpha-10 chr11 GO:1902531 Not Cancer Driver No 65 0.144 34 5 0.147 0
CHRNA9 CHRNA9 Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 chr4 GO:1902531 Not Cancer Driver No 76 0.159 23 6 0.261 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:1902531 Not Cancer Driver No 24 0.126 6 1 0.167 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 GO:1902531 Not Cancer Driver No 284 0.14 1017 160 0.157 3
CLEC16A CLEC16A Q2KHT3 Protein CLEC16A chr16 GO:1902531 Not Cancer Driver No 149 0.142 374 53 0.142 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:1902531 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:1902531 Not Cancer Driver No 69 0.154 156 27 0.173 0
CMKLR1 CMKLR1 Q99788 Chemerin-like receptor 1 chr12 GO:1902531 Not Cancer Driver No 107 0.287 24 13 0.542 0
CNKSR3 CNKSR3 Q6P9H4 Connector enhancer of kinase suppressor of ras 3 chr6 GO:1902531 Not Cancer Driver No 72 0.13 269 43 0.16 0
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:1902531 Census Yes 402 0.274 1182 337 0.285 103
COPS3 COPS3 Q9UNS2 COP9 signalosome complex subunit 3 chr17 GO:1902531 Not Cancer Driver No 55 0.13 67 10 0.149 0
CPNE1_ENST00000352393 CPNE1 Q99829 Copine-1 chr20 GO:1902531 Not Cancer Driver No 74 0.138 80 7 0.087 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:1902531 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:1902531 Census Yes 68 0.131 372 50 0.134 0
CRK CRK P46108 Adapter molecule crk chr17 GO:1902531 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:1902531 Not Cancer Driver No 76 0.13 91 5 0.055 0
CRYBA1 CRYBA1 P05813 Beta-crystallin A3 chr17 GO:1902531 Not Cancer Driver No 29 0.135 52 11 0.212 0
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:1902531 Not Cancer Driver No 20 0.097 7 0 0.0 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:1902531 Not Cancer Driver No 41 0.091 18 1 0.056 0
CTNS_ENST00000046640 CTNS O60931 Cystinosin chr17 GO:1902531 Not Cancer Driver No 34 0.093 0 0 0.0 31
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:1902531 Census, Compendium Yes 123 0.16 167 23 0.138 3
CUL4A CUL4A Q13619 Cullin-4A chr13 GO:1902531 Not Cancer Driver No 64 0.084 102 2 0.02 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:1902531 Not Cancer Driver No 16 0.172 0 0 0.0 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 GO:1902531 Census, Compendium Yes 116 0.121 213 31 0.146 3
CYTH1_ENST00000446868 CYTH1 Q15438 Cytohesin-1 chr17 GO:1902531 Not Cancer Driver No 59 0.148 93 15 0.161 0
CYTH2_ENST00000641098 CYTH2 Q99418 Cytohesin-2 chr19 GO:1902531 Not Cancer Driver No 55 0.138 93 12 0.129 0
CYTH3_ENST00000396741 CYTH3 O43739 Cytohesin-3 chr7 GO:1902531 Not Cancer Driver No 49 0.122 96 12 0.125 0
CYTH4 CYTH4 Q9UIA0 Cytohesin-4 chr22 GO:1902531 Not Cancer Driver No 70 0.178 52 10 0.192 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:1902531 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:1902531 Not Cancer Driver No 131 0.11 681 68 0.1 0
DACT1 DACT1 Q9NYF0 Dapper homolog 1 chr14 GO:1902531 Not Cancer Driver No 163 0.195 598 127 0.212 1
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:1902531 Not Cancer Driver No 102 0.114 485 61 0.126 4
DCN DCN P07585 Decorin chr12 GO:1902531 Not Cancer Driver No 96 0.267 81 26 0.321 0
DDIAS DDIAS Q8IXT1 DNA damage-induced apoptosis suppressor protein chr11 GO:1902531 Not Cancer Driver No 125 0.125 370 59 0.159 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:1902531 Census Yes 29 0.172 160 27 0.169 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 GO:1902531 Not Cancer Driver No 49 0.114 34 8 0.235 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:1902531 Census, Compendium Yes 133 0.201 301 47 0.156 18
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:1902531 Census Yes 74 0.121 225 23 0.102 0
DDX60 DDX60 Q8IY21 Probable ATP-dependent RNA helicase DDX60 chr4 GO:1902531 Not Cancer Driver No 224 0.131 131 12 0.092 0
DENND1A DENND1A Q8TEH3 DENN domain-containing protein 1A chr9 GO:1902531 Not Cancer Driver No 117 0.116 589 76 0.129 0
DENND3 DENND3 A2RUS2 DENN domain-containing protein 3 chr8 GO:1902531 Not Cancer Driver No 192 0.16 118 22 0.186 0
DENND4A_ENST00000431932 DENND4A Q7Z401 C-myc promoter-binding protein chr15 GO:1902531 Not Cancer Driver No 199 0.107 570 64 0.112 0
DENND4B DENND4B O75064 DENN domain-containing protein 4B chr1 GO:1902531 Not Cancer Driver No 201 0.134 498 72 0.145 0
DENND4C_ENST00000602925 DENND4C Q5VZ89 DENN domain-containing protein 4C chr9 GO:1902531 Not Cancer Driver No 190 0.1 710 69 0.097 0
DEPDC5_ENST00000382112 DEPDC5 O75140 GATOR complex protein DEPDC5 chr22 GO:1902531 Not Cancer Driver No 226 0.141 575 91 0.158 7
DEPTOR DEPTOR Q8TB45 DEP domain-containing mTOR-interacting protein chr8 GO:1902531 Not Cancer Driver No 57 0.139 125 12 0.096 0
DGKD DGKD Q16760 Diacylglycerol kinase delta chr2 GO:1902531 Not Cancer Driver No 160 0.132 441 60 0.136 0
DGKG DGKG P49619 Diacylglycerol kinase gamma chr3 GO:1902531 Not Cancer Driver No 160 0.202 182 43 0.236 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:1902531 Not Cancer Driver No 56 0.059 264 11 0.042 0
DHX58 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 GO:1902531 Not Cancer Driver No 62 0.091 84 8 0.095 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:1902531 Not Cancer Driver No 58 0.218 47 8 0.17 0
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:1902531 Not Cancer Driver No 331 0.217 922 237 0.257 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:1902531 Not Cancer Driver No 120 0.133 460 67 0.146 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 GO:1902531 Not Cancer Driver No 230 0.12 1119 135 0.121 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 GO:1902531 Not Cancer Driver No 37 0.093 153 16 0.105 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:1902531 Not Cancer Driver No 67 0.091 212 23 0.108 7
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:1902531 Census Yes 138 0.159 270 43 0.159 22
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:1902531 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:1902531 Not Cancer Driver No 88 0.22 45 17 0.378 0
DUPD1 DUSP29 Q68J44 Dual specificity phosphatase 29 chr10 GO:1902531 Not Cancer Driver No 47 0.214 55 7 0.127 0
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 GO:1902531 Not Cancer Driver No 31 0.084 7 0 0.0 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:1902531 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 GO:1902531 Compendium Yes 70 0.105 273 34 0.125 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:1902531 Not Cancer Driver No 34 0.157 15 5 0.333 0
DUSP26 DUSP26 Q9BV47 Dual specificity protein phosphatase 26 chr8 GO:1902531 Not Cancer Driver No 56 0.265 14 6 0.429 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 GO:1902531 Not Cancer Driver No 21 0.114 4 1 0.25 0
DUSP4 DUSP4 Q13115 Dual specificity protein phosphatase 4 chr8 GO:1902531 Not Cancer Driver No 43 0.109 63 9 0.143 0
DUSP6 DUSP6 Q16828 Dual specificity protein phosphatase 6 chr12 GO:1902531 Not Cancer Driver No 43 0.113 39 3 0.077 4
DUSP9 DUSP9 Q99956 Dual specificity protein phosphatase 9 chrX GO:1902531 Not Cancer Driver No 40 0.104 109 12 0.11 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:1902531 Not Cancer Driver No 96 0.13 514 64 0.125 0
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 GO:1902531 Not Cancer Driver No 97 0.135 437 58 0.133 0
DYNC1LI1 DYNC1LI1 Q9Y6G9 Cytoplasmic dynein 1 light intermediate chain 1 chr3 GO:1902531 Not Cancer Driver No 46 0.088 208 20 0.096 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:1902531 Not Cancer Driver No 135 0.177 447 73 0.163 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 GO:1902531 Not Cancer Driver No 77 0.128 294 39 0.133 0
DYRK3 DYRK3 O43781 Dual specificity tyrosine-phosphorylation-regulated kinase 3 chr1 GO:1902531 Not Cancer Driver No 87 0.148 193 20 0.104 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:1902531 Not Cancer Driver No 37 0.175 97 20 0.206 3
EEF1E1 EEF1E1 O43324 Eukaryotic translation elongation factor 1 epsilon-1 chr6 GO:1902531 Not Cancer Driver No 27 0.155 11 1 0.091 0
EFHB EFHB Q8N7U6 EF-hand domain-containing family member B chr3 GO:1902531 Not Cancer Driver No 177 0.212 343 78 0.227 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:1902531 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:1902531 Census, Compendium Yes 444 0.367 223 35 0.157 1
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:1902531 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF3A EIF3A Q14152 Eukaryotic translation initiation factor 3 subunit A chr10 GO:1902531 Not Cancer Driver No 181 0.131 835 130 0.156 0
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 GO:1902531 Not Cancer Driver No 37 0.24 21 5 0.238 5
ELL3 ELL3 Q9HB65 RNA polymerase II elongation factor ELL3 chr15 GO:1902531 Not Cancer Driver No 50 0.126 186 13 0.07 0
EMC10 EMC10 Q5UCC4 ER membrane protein complex subunit 10 chr19 GO:1902531 Not Cancer Driver No 25 0.095 109 15 0.138 0
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 GO:1902531 Not Cancer Driver No 125 0.123 669 69 0.103 0
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:1902531 Not Cancer Driver No 51 0.118 21 2 0.095 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:1902531 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:1902531 Compendium Yes 171 0.175 187 39 0.209 3
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:1902531 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:1902531 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPO EPO P01588 Erythropoietin chr7 GO:1902531 Not Cancer Driver No 27 0.14 9 1 0.111 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:1902531 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:1902531 Census, Compendium Yes 428 0.327 323 116 0.359 2
ERBIN_ENST00000284037 ERBIN Q96RT1 Erbin chr5 GO:1902531 Not Cancer Driver No 167 0.118 967 118 0.122 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:1902531 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:1902531 Not Cancer Driver No 192 0.207 213 45 0.211 0
ERP29 ERP29 P30040 Endoplasmic reticulum resident protein 29 chr12 GO:1902531 Not Cancer Driver No 29 0.111 34 5 0.147 0
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:1902531 Not Cancer Driver No 55 0.119 297 37 0.125 0
ETAA1 ETAA1 Q9NY74 Ewing's tumor-associated antigen 1 chr2 GO:1902531 Not Cancer Driver No 101 0.109 735 75 0.102 0
EZR EZR P15311 Ezrin chr6 GO:1902531 Census Yes 66 0.113 295 35 0.119 0
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:1902531 Not Cancer Driver No 47 0.157 72 15 0.208 0
F2 F2 P00734 Prothrombin chr11 GO:1902531 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:1902531 Not Cancer Driver No 73 0.172 19 2 0.105 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:1902531 Not Cancer Driver No 55 0.139 7 2 0.286 0
F2RL2 F2RL2 O00254 Proteinase-activated receptor 3 chr5 GO:1902531 Not Cancer Driver No 54 0.144 0 0 0.0 0
F2RL3 F2RL3 Q96RI0 Proteinase-activated receptor 4 chr19 GO:1902531 Not Cancer Driver No 43 0.112 46 4 0.087 0
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:1902531 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBLN1 FBLN1 P23142 Fibulin-1 chr22 GO:1902531 Compendium Yes 122 0.174 22 3 0.136 0
FBXO4 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:1902531 Not Cancer Driver No 55 0.142 68 7 0.103 0
FBXO8 FBXO8 Q9NRD0 F-box only protein 8 chr4 GO:1902531 Not Cancer Driver No 46 0.144 25 1 0.04 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:1902531 Census, Compendium Yes 322 0.455 230 38 0.165 0
FEM1B FEM1B Q9UK73 Protein fem-1 homolog B chr15 GO:1902531 Not Cancer Driver No 69 0.11 33 3 0.091 0
FFAR4_ENST00000371481 FFAR4 Q5NUL3 Free fatty acid receptor 4 chr10 GO:1902531 Not Cancer Driver No 47 0.13 0 0 0.0 0
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:1902531 Not Cancer Driver No 113 0.173 158 26 0.165 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:1902531 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:1902531 Not Cancer Driver No 84 0.335 97 51 0.526 7
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:1902531 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:1902531 Census, Compendium Yes 152 0.185 230 43 0.187 74
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:1902531 Not Cancer Driver No 85 0.161 52 8 0.154 0
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 GO:1902531 Not Cancer Driver No 30 0.108 0 0 0.0 0
FIS1 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 GO:1902531 Not Cancer Driver No 25 0.164 6 0 0.0 0
FKTN_ENST00000602661 FKTN O75072 Ribitol-5-phosphate transferase FKTN chr9 GO:1902531 Not Cancer Driver No 51 0.111 0 0 0.0 10
FLCN FLCN Q8NFG4 Folliculin chr17 GO:1902531 Census, Compendium Yes 59 0.102 157 19 0.121 5
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:1902531 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:1902531 Census, Compendium Yes 200 0.201 64 27 0.422 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:1902531 Census, Compendium Yes 253 0.186 259 41 0.158 13
FN1 FN1 P02751 Fibronectin chr2 GO:1902531 Compendium Yes 394 0.159 1243 185 0.149 8
FOXM1_ENST00000359843 FOXM1 Q08050 Forkhead box protein M1 chr12 GO:1902531 Not Cancer Driver No 97 0.127 601 73 0.121 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:1902531 Census, Compendium Yes 81 0.124 584 75 0.128 0
FRMD1 FRMD1 Q8N878 FERM domain-containing protein 1 chr6 GO:1902531 Not Cancer Driver No 82 0.149 259 36 0.139 0
FRMD7 FRMD7 Q6ZUT3 FERM domain-containing protein 7 chrX GO:1902531 Not Cancer Driver No 147 0.206 256 59 0.23 25
FSHR FSHR P23945 Follicle-stimulating hormone receptor chr2 GO:1902531 Not Cancer Driver No 226 0.325 28 11 0.393 16
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:1902531 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:1902531 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:1902531 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:1902531 Not Cancer Driver No 72 0.104 146 3 0.021 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 GO:1902531 Not Cancer Driver No 9 0.077 11 0 0.0 0
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:1902531 Not Cancer Driver No 10 0.061 39 5 0.128 0
GADD45B GADD45B O75293 Growth arrest and DNA damage-inducible protein GADD45 beta chr19 GO:1902531 Not Cancer Driver No 9 0.056 14 0 0.0 0
GADD45G GADD45G O95257 Growth arrest and DNA damage-inducible protein GADD45 gamma chr9 GO:1902531 Not Cancer Driver No 13 0.082 20 2 0.1 0
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 GO:1902531 Not Cancer Driver No 216 0.116 669 76 0.114 0
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:1902531 Not Cancer Driver No 92 0.155 166 27 0.163 0
GDF6 GDF6 Q6KF10 Growth/differentiation factor 6 chr8 GO:1902531 Not Cancer Driver No 91 0.2 225 46 0.204 14
GEN1_ENST00000381254 GEN1 Q17RS7 Flap endonuclease GEN homolog 1 chr2 GO:1902531 Not Cancer Driver No 109 0.12 339 52 0.153 0
GH1 GH1 P01241 Somatotropin chr17 GO:1902531 Not Cancer Driver No 54 0.249 24 9 0.375 15
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:1902531 Not Cancer Driver No 35 0.229 68 16 0.235 0
GIPR GIPR P48546 Gastric inhibitory polypeptide receptor chr19 GO:1902531 Not Cancer Driver No 45 0.097 41 0 0.0 0
GPATCH3 GPATCH3 Q96I76 G patch domain-containing protein 3 chr1 GO:1902531 Not Cancer Driver No 64 0.122 354 48 0.136 0
GPD1L GPD1L Q8N335 Glycerol-3-phosphate dehydrogenase 1-like protein chr3 GO:1902531 Not Cancer Driver No 40 0.114 13 1 0.077 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:1902531 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPR137B GPR137B O60478 Integral membrane protein GPR137B chr1 GO:1902531 Not Cancer Driver No 49 0.123 47 1 0.021 0
GPR137C GPR137C Q8N3F9 Integral membrane protein GPR137C chr14 GO:1902531 Not Cancer Driver No 41 0.096 47 0 0.0 0
GPR137_ENST00000313074 GPR137 Q96N19 Integral membrane protein GPR137 chr11 GO:1902531 Not Cancer Driver No 66 0.158 41 11 0.268 0
GPR143 GPR143 P51810 G-protein coupled receptor 143 chrX GO:1902531 Not Cancer Driver No 47 0.116 83 14 0.169 34
GPR17 GPR17 Q13304 Uracil nucleotide/cysteinyl leukotriene receptor chr2 GO:1902531 Not Cancer Driver No 57 0.155 16 4 0.25 0
GPR174_ENST00000276077 GPR174 Q9BXC1 Probable G-protein coupled receptor 174 chrX GO:1902531 Not Cancer Driver No 115 0.345 0 0 0.0 0
GPR18_ENST00000397470 GPR18 Q14330 N-arachidonyl glycine receptor chr13 GO:1902531 Not Cancer Driver No 36 0.109 0 0 0.0 0
GPR20 GPR20 Q99678 G-protein coupled receptor 20 chr8 GO:1902531 Not Cancer Driver No 77 0.215 44 11 0.25 0
GPR3 GPR3 P46089 G-protein coupled receptor 3 chr1 GO:1902531 Not Cancer Driver No 38 0.115 13 1 0.077 0
GPR35_ENST00000403859 GPR35 Q9HC97 G-protein coupled receptor 35 chr2 GO:1902531 Not Cancer Driver No 57 0.184 0 0 0.0 0
GPR4 GPR4 P46093 G-protein coupled receptor 4 chr19 GO:1902531 Not Cancer Driver No 57 0.157 44 8 0.182 0
GPR55 GPR55 Q9Y2T6 G-protein coupled receptor 55 chr2 GO:1902531 Not Cancer Driver No 64 0.201 0 0 0.0 0
GPR61_ENST00000618721 GPR61 Q9BZJ8 G-protein coupled receptor 61 chr1 GO:1902531 Not Cancer Driver No 72 0.16 103 23 0.223 0
GPR62 GPR62 Q9BZJ7 G-protein coupled receptor 62 chr3 GO:1902531 Not Cancer Driver No 20 0.054 52 9 0.173 0
GPR65 GPR65 Q8IYL9 Psychosine receptor chr14 GO:1902531 Not Cancer Driver No 70 0.208 0 0 0.0 0
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 GO:1902531 Not Cancer Driver No 29 0.089 319 26 0.082 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:1902531 Not Cancer Driver No 38 0.187 12 1 0.083 0
GRINA_ENST00000395068 GRINA Q7Z429 Protein lifeguard 1 chr8 GO:1902531 Not Cancer Driver No 39 0.105 150 15 0.1 0
GSDME_ENST00000409775 GSDME O60443 Gasdermin-E chr7 GO:1902531 Not Cancer Driver No 81 0.163 14 3 0.214 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:1902531 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:1902531 Not Cancer Driver No 32 0.152 0 0 0.0 0
GUCA1A GUCA1A P43080 Guanylyl cyclase-activating protein 1 chr6 GO:1902531 Not Cancer Driver No 39 0.194 20 4 0.2 17
GUCY1A1_ENST00000513574 GUCY1A1 Q02108 Guanylate cyclase soluble subunit alpha-1 chr4 GO:1902531 Not Cancer Driver No 181 0.262 54 8 0.148 0
GUCY1A2_ENST00000526355 GUCY1A2 P33402 Guanylate cyclase soluble subunit alpha-2 chr11 GO:1902531 Not Cancer Driver No 191 0.261 187 48 0.257 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:1902531 Not Cancer Driver No 47 0.217 124 29 0.234 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:1902531 Not Cancer Driver No 44 0.158 219 32 0.146 2
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:1902531 Not Cancer Driver No 103 0.212 446 94 0.211 0
HCST HCST Q9UBK5 Hematopoietic cell signal transducer chr19 GO:1902531 Not Cancer Driver No 6 0.065 12 0 0.0 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:1902531 Not Cancer Driver No 65 0.152 61 8 0.131 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 GO:1902531 Not Cancer Driver No 91 0.096 570 50 0.088 0
HEG1 HEG1 Q9ULI3 Protein HEG homolog 1 chr3 GO:1902531 Not Cancer Driver No 173 0.125 974 135 0.139 0
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:1902531 Census Yes 38 0.097 248 17 0.069 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 GO:1902531 Not Cancer Driver No 40 0.111 352 40 0.114 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:1902531 Compendium Yes 233 0.32 43 16 0.372 0
HIC1 HIC1 Q14526 Hypermethylated in cancer 1 protein chr17 GO:1902531 Not Cancer Driver No 24 0.033 361 6 0.017 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:1902531 Census Yes 118 0.143 435 51 0.117 0
HINT1 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 GO:1902531 Not Cancer Driver No 11 0.087 6 0 0.0 6
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:1902531 Not Cancer Driver No 154 0.129 686 96 0.14 0
HIPK3 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:1902531 Not Cancer Driver No 128 0.105 559 51 0.091 0
HIPK4 HIPK4 Q8NE63 Homeodomain-interacting protein kinase 4 chr19 GO:1902531 Not Cancer Driver No 87 0.141 258 23 0.089 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:1902531 Not Cancer Driver No 94 0.278 85 22 0.259 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 GO:1902531 Not Cancer Driver No 75 0.162 302 59 0.195 0
HOMER2 HOMER2 Q9NSB8 Homer protein homolog 2 chr15 GO:1902531 Not Cancer Driver No 53 0.15 233 32 0.137 1
HOMER3_ENST00000542541 HOMER3 Q9NSC5 Homer protein homolog 3 chr19 GO:1902531 Not Cancer Driver No 31 0.086 251 15 0.06 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:1902531 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:1902531 Not Cancer Driver No 15 0.023 200 5 0.025 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:1902531 Not Cancer Driver No 10 0.049 118 8 0.068 20
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:1902531 Compendium Yes 44 0.096 127 9 0.071 2
HTT HTT P42858 Huntingtin chr4 GO:1902531 Not Cancer Driver No 336 0.107 666 69 0.104 2
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:1902531 Not Cancer Driver No 52 0.11 8 1 0.125 0
HYOU1 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 GO:1902531 Not Cancer Driver No 132 0.132 373 47 0.126 0
IAPP_ENST00000539393 IAPP P10997 Islet amyloid polypeptide chr12 GO:1902531 Not Cancer Driver No 22 0.247 10 2 0.2 0
IFI35_ENST00000415816 IFI35 P80217 Interferon-induced 35 kDa protein chr17 GO:1902531 Not Cancer Driver No 33 0.115 63 10 0.159 0
IGBP1_ENST00000356413 IGBP1 P78318 Immunoglobulin-binding protein 1 chrX GO:1902531 Not Cancer Driver No 51 0.15 193 28 0.145 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:1902531 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:1902531 Not Cancer Driver No 45 0.231 87 23 0.264 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:1902531 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL19_ENST00000270218 IL19 Q9UHD0 Interleukin-19 chr1 GO:1902531 Not Cancer Driver No 16 0.09 0 0 0.0 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:1902531 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL20RA IL20RA Q9UHF4 Interleukin-20 receptor subunit alpha chr6 GO:1902531 Not Cancer Driver No 72 0.13 231 29 0.126 0
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 GO:1902531 Not Cancer Driver No 33 0.118 169 26 0.154 0
ING4 ING4 Q9UNL4 Inhibitor of growth protein 4 chr12 GO:1902531 Not Cancer Driver No 31 0.124 108 15 0.139 0
INPP5E INPP5E Q9NRR6 Phosphatidylinositol polyphosphate 5-phosphatase type IV chr9 GO:1902531 Not Cancer Driver No 43 0.067 272 16 0.059 15
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:1902531 Not Cancer Driver No 42 0.094 34 2 0.059 7
INS INS P01308 Insulin chr11 GO:1902531 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSL3_ENST00000317306 INSL3 P51460 Insulin-like 3 chr19 GO:1902531 Not Cancer Driver No 18 0.137 34 12 0.353 3
INSR INSR P06213 Insulin receptor chr19 GO:1902531 Not Cancer Driver No 190 0.137 280 57 0.204 64
IQCJ-SCHIP1 IQCJ-SCHIP1 B3KU38 IQCJ-SCHIP1 readthrough transcript protein chr3 GO:1902531 Not Cancer Driver No 76 0.135 517 71 0.137 0
IQSEC1_ENST00000273221 IQSEC1 Q6DN90 IQ motif and SEC7 domain-containing protein 1 chr3 GO:1902531 Not Cancer Driver No 141 0.146 610 97 0.159 2
IQSEC2_ENST00000396435 IQSEC2 Q5JU85 IQ motif and SEC7 domain-containing protein 2 chrX GO:1902531 Not Cancer Driver No 163 0.11 1139 97 0.085 5
IQSEC3 IQSEC3 Q9UPP2 IQ motif and SEC7 domain-containing protein 3 chr12 GO:1902531 Not Cancer Driver No 166 0.14 682 85 0.125 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:1902531 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITFG2 ITFG2 Q969R8 KICSTOR complex protein ITFG2 chr12 GO:1902531 Not Cancer Driver No 59 0.132 61 9 0.148 0
ITGA3 ITGA3 P26006 Integrin alpha-3 chr17 GO:1902531 Not Cancer Driver No 106 0.101 129 18 0.14 3
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:1902531 Census Yes 153 0.146 92 9 0.098 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:1902531 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:1902531 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITPR1_ENST00000354582 ITPR1 Q14643 Inositol 1,4,5-trisphosphate receptor type 1 chr3 GO:1902531 Not Cancer Driver No 390 0.141 581 76 0.131 6
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:1902531 Census, Compendium Yes 136 0.12 59 5 0.085 5
KANK1_ENST00000382303 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 GO:1902531 Not Cancer Driver No 183 0.135 804 100 0.124 0
KAT6A_ENST00000406337 KAT6A Q92794 Histone acetyltransferase KAT6A chr8 GO:1902531 Census, Compendium Yes 273 0.136 1420 193 0.136 0
KBTBD6 KBTBD6 Q86V97 Kelch repeat and BTB domain-containing protein 6 chr13 GO:1902531 Not Cancer Driver No 96 0.142 80 12 0.15 0
KBTBD7 KBTBD7 Q8WVZ9 Kelch repeat and BTB domain-containing protein 7 chr13 GO:1902531 Not Cancer Driver No 92 0.135 105 6 0.057 0
KCTD10 KCTD10 Q9H3F6 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 chr12 GO:1902531 Not Cancer Driver No 68 0.217 73 19 0.26 0
KCTD13 KCTD13 Q8WZ19 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 chr16 GO:1902531 Not Cancer Driver No 33 0.1 95 10 0.105 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:1902531 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:1902531 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 GO:1902531 Not Cancer Driver No 222 0.135 774 102 0.132 2
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:1902531 Census, Compendium Yes 226 0.232 83 33 0.398 21
KL KL Q9UEF7 Klotho chr13 GO:1902531 Not Cancer Driver No 175 0.173 104 5 0.048 1
KLB KLB Q86Z14 Beta-klotho chr4 GO:1902531 Not Cancer Driver No 139 0.133 6 1 0.167 0
KLHL22 KLHL22 Q53GT1 Kelch-like protein 22 chr22 GO:1902531 Not Cancer Driver No 90 0.142 50 8 0.16 0
KLHL31 KLHL31 Q9H511 Kelch-like protein 31 chr6 GO:1902531 Not Cancer Driver No 69 0.109 32 1 0.031 0
KPTN KPTN Q9Y664 KICSTOR complex protein kaptin chr19 GO:1902531 Not Cancer Driver No 44 0.101 21 2 0.095 0
KRAS KRAS P01116 GTPase KRas chr12 GO:1902531 Census, Compendium Yes 788 4.169 7 2 0.286 27
LACRT LACRT Q9GZZ8 Extracellular glycoprotein lacritin chr12 GO:1902531 Not Cancer Driver No 38 0.275 90 27 0.3 0
LAMTOR5_ENST00000602318 LAMTOR5 O43504 Ragulator complex protein LAMTOR5 chr1 GO:1902531 Not Cancer Driver No 10 0.11 17 0 0.0 0
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:1902531 Not Cancer Driver No 133 0.113 97 10 0.103 1
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:1902531 Census Yes 86 0.169 94 13 0.138 1
LCMT1 LCMT1 Q9UIC8 Leucine carboxyl methyltransferase 1 chr16 GO:1902531 Not Cancer Driver No 43 0.129 2 0 0.0 0
LEMD2_ENST00000614475 LEMD2 Q8NC56 LEM domain-containing protein 2 chr6 GO:1902531 Not Cancer Driver No 44 0.087 211 4 0.019 2
LEMD3 LEMD3 Q9Y2U8 Inner nuclear membrane protein Man1 chr12 GO:1902531 Not Cancer Driver No 78 0.086 509 33 0.065 0
LEP LEP P41159 Leptin chr7 GO:1902531 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:1902531 Not Cancer Driver No 54 0.152 65 16 0.246 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:1902531 Not Cancer Driver No 25 0.124 0 0 0.0 0
LIMD1 LIMD1 Q9UGP4 LIM domain-containing protein 1 chr3 GO:1902531 Not Cancer Driver No 58 0.086 428 36 0.084 0
LITAF_ENST00000570904 LITAF Q99732 Lipopolysaccharide-induced tumor necrosis factor-alpha factor chr16 GO:1902531 Not Cancer Driver No 21 0.13 67 6 0.09 5
LMCD1 LMCD1 Q9NZU5 LIM and cysteine-rich domains protein 1 chr3 GO:1902531 Not Cancer Driver No 63 0.173 110 24 0.218 0
LMO3_ENST00000534946 LMO3 Q8TAP4 LIM domain only protein 3 chr12 GO:1902531 Not Cancer Driver No 30 0.207 1 0 0.0 0
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 GO:1902531 Not Cancer Driver No 79 0.217 21 6 0.286 0
LPAR4 LPAR4 Q99677 Lysophosphatidic acid receptor 4 chrX GO:1902531 Compendium Yes 123 0.332 10 3 0.3 0
LPAR6_ENST00000620633 LPAR6 P43657 Lysophosphatidic acid receptor 6 chr13 GO:1902531 Not Cancer Driver No 39 0.113 0 0 0.0 3
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:1902531 Not Cancer Driver No 519 0.205 90 17 0.189 23
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:1902531 Census Yes 95 0.186 84 12 0.143 0
MAD1L1_ENST00000399654 MAD1L1 Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 chr7 GO:1902531 Not Cancer Driver No 117 0.163 526 77 0.146 0
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 GO:1902531 Not Cancer Driver No 26 0.127 12 1 0.083 0
MAD2L1BP_ENST00000372171 MAD2L1BP Q15013 MAD2L1-binding protein chr6 GO:1902531 Not Cancer Driver No 26 0.095 55 7 0.127 0
MADD MADD Q8WXG6 MAP kinase-activating death domain protein chr11 GO:1902531 Not Cancer Driver No 207 0.126 723 81 0.112 4
MAGEA3 MAGEA3 P43357 Melanoma-associated antigen 3 chrX GO:1902531 Not Cancer Driver No 79 0.252 103 18 0.175 0
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:1902531 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 GO:1902531 Not Cancer Driver No 104 0.3 75 27 0.36 0
MAP2K6 MAP2K6 P52564 Dual specificity mitogen-activated protein kinase kinase 6 chr17 GO:1902531 Not Cancer Driver No 48 0.144 55 11 0.2 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:1902531 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:1902531 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:1902531 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:1902531 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:1902531 Census Yes 157 0.163 593 91 0.153 0
MAP3K20 MAP3K20 Q9NYL2 Mitogen-activated protein kinase kinase kinase 20 chr2 GO:1902531 Not Cancer Driver No 101 0.126 294 41 0.139 1
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 GO:1902531 Not Cancer Driver No 74 0.118 355 44 0.124 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:1902531 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:1902531 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:1902531 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:1902531 Not Cancer Driver No 78 0.095 243 23 0.095 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 GO:1902531 Not Cancer Driver No 143 0.115 649 55 0.085 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:1902531 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:1902531 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 GO:1902531 Not Cancer Driver No 79 0.111 444 40 0.09 1
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 GO:1902531 Not Cancer Driver No 51 0.108 101 12 0.119 0
MAPRE2 MAPRE2 Q15555 Microtubule-associated protein RP/EB family member 2 chr18 GO:1902531 Not Cancer Driver No 50 0.153 176 28 0.159 3
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:1902531 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARCH7 MARCHF7 Q9H992 E3 ubiquitin-protein ligase MARCHF7 chr2 GO:1902531 Not Cancer Driver No 85 0.121 550 68 0.124 0
MARK3 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 GO:1902531 Not Cancer Driver No 92 0.122 376 49 0.13 1
MARVELD3_ENST00000268485 MARVELD3 Q96A59 MARVEL domain-containing protein 3 chr16 GO:1902531 Not Cancer Driver No 40 0.1 179 10 0.056 0
MAZ_ENST00000322945 MAZ P56270 Myc-associated zinc finger protein chr16 GO:1902531 Not Cancer Driver No 46 0.096 249 22 0.088 0
MC1R_ENST00000639847 MC1R Q01726 Melanocyte-stimulating hormone receptor chr16 GO:1902531 Not Cancer Driver No 39 0.123 0 0 0.0 5
MCF2L_ENST00000375608 MCF2L O15068 Guanine nucleotide exchange factor DBS chr13 GO:1902531 Not Cancer Driver No 173 0.152 410 54 0.132 0
MCL1 MCL1 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 chr1 GO:1902531 Not Cancer Driver No 30 0.086 203 21 0.103 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:1902531 Census, Compendium Yes 56 0.114 297 37 0.125 0
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 GO:1902531 Census, Compendium Yes 287 0.233 749 159 0.212 3
MEN1 MEN1 O00255 Menin chr11 GO:1902531 Census, Compendium Yes 73 0.119 228 15 0.066 90
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:1902531 Census, Compendium Yes 226 0.163 62 15 0.242 19
MFHAS1 MFHAS1 Q9Y4C4 Malignant fibrous histiocytoma-amplified sequence 1 chr8 GO:1902531 Not Cancer Driver No 95 0.09 98 9 0.092 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:1902531 Not Cancer Driver No 4 0.035 0 0 0.0 0
MINK1 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 GO:1902531 Not Cancer Driver No 113 0.085 740 56 0.076 0
MIOS_ENST00000405785 MIOS Q9NXC5 GATOR complex protein MIOS chr7 GO:1902531 Not Cancer Driver No 98 0.112 72 4 0.056 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 GO:1902531 Not Cancer Driver No 45 0.108 145 16 0.11 0
MLF1_ENST00000355893 MLF1 P58340 Myeloid leukemia factor 1 chr3 GO:1902531 Census Yes 40 0.149 243 37 0.152 0
MOB3B MOB3B Q86TA1 MOB kinase activator 3B chr9 GO:1902531 Not Cancer Driver No 29 0.134 16 2 0.125 0
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:1902531 Not Cancer Driver No 68 0.181 64 11 0.172 0
MSX1 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:1902531 Not Cancer Driver No 39 0.129 197 16 0.081 7
MTM1 MTM1 Q13496 Myotubularin chrX GO:1902531 Not Cancer Driver No 112 0.186 79 9 0.114 57
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 GO:1902531 Not Cancer Driver No 104 0.287 8 1 0.125 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:1902531 Census, Compendium Yes 379 0.149 296 37 0.125 18
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:1902531 Census Yes 40 0.032 1050 19 0.018 0
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:1902531 Not Cancer Driver No 48 0.136 16 2 0.125 0
MYADM MYADM Q96S97 Myeloid-associated differentiation marker chr19 GO:1902531 Not Cancer Driver No 73 0.227 0 0 0.0 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:1902531 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYDGF MYDGF Q969H8 Myeloid-derived growth factor chr19 GO:1902531 Not Cancer Driver No 23 0.133 26 4 0.154 0
MYOC MYOC Q99972 Myocilin chr1 GO:1902531 Not Cancer Driver No 92 0.183 196 43 0.219 58
MYOZ1 MYOZ1 Q9NP98 Myozenin-1 chr10 GO:1902531 Not Cancer Driver No 49 0.164 223 39 0.175 0
MYOZ2 MYOZ2 Q9NPC6 Myozenin-2 chr4 GO:1902531 Not Cancer Driver No 50 0.189 197 38 0.193 2
NACC2_ENST00000371753 NACC2 Q96BF6 Nucleus accumbens-associated protein 2 chr9 GO:1902531 Not Cancer Driver No 24 0.041 238 10 0.042 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:1902531 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:1902531 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:1902531 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:1902531 Not Cancer Driver No 247 0.219 51 10 0.196 4
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 GO:1902531 Census, Compendium Yes 352 0.144 2347 340 0.145 0
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 GO:1902531 Not Cancer Driver No 80 0.125 313 45 0.144 0
NDRG2 NDRG2 Q9UN36 Protein NDRG2 chr14 GO:1902531 Not Cancer Driver No 45 0.121 111 8 0.072 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:1902531 Not Cancer Driver No 150 0.114 711 79 0.111 0
NEK8 NEK8 Q86SG6 Serine/threonine-protein kinase Nek8 chr17 GO:1902531 Not Cancer Driver No 102 0.147 167 40 0.24 3
NET1 NET1 Q7Z628 Neuroepithelial cell-transforming gene 1 protein chr10 GO:1902531 Not Cancer Driver No 60 0.101 294 37 0.126 0
NEUROD2 NEUROD2 Q15784 Neurogenic differentiation factor 2 chr17 GO:1902531 Not Cancer Driver No 26 0.068 210 14 0.067 2
NF1 NF1 P21359 Neurofibromin chr17 GO:1902531 Census, Compendium Yes 375 0.132 406 47 0.116 85
NF2 NF2 P35240 Merlin chr22 GO:1902531 Census, Compendium Yes 69 0.116 252 26 0.103 16
NFAT5_ENST00000354436 NFAT5 O94916 Nuclear factor of activated T-cells 5 chr16 GO:1902531 Not Cancer Driver No 142 0.093 1307 119 0.091 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:1902531 Census, Compendium Yes 228 0.377 402 62 0.154 4
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:1902531 Not Cancer Driver No 35 0.15 171 16 0.094 0
NLRC3 NLRC3 Q7RTR2 NLR family CARD domain-containing protein 3 chr16 GO:1902531 Not Cancer Driver No 176 0.165 147 33 0.224 0
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:1902531 Not Cancer Driver No 310 0.292 116 43 0.371 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:1902531 Not Cancer Driver No 339 0.327 64 33 0.516 37
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:1902531 Not Cancer Driver No 106 0.119 203 28 0.138 0
NLRX1_ENST00000409265 NLRX1 Q86UT6 NLR family member X1 chr11 GO:1902531 Not Cancer Driver No 158 0.162 94 13 0.138 0
NME5 NME5 P56597 Nucleoside diphosphate kinase homolog 5 chr5 GO:1902531 Not Cancer Driver No 17 0.08 6 0 0.0 0
NMI NMI Q13287 N-myc-interactor chr2 GO:1902531 Not Cancer Driver No 34 0.111 104 12 0.115 0
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:1902531 Not Cancer Driver No 20 0.096 179 17 0.095 2
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX GO:1902531 Census, Compendium Yes 101 0.214 349 64 0.183 0
NOP2_ENST00000322166 NOP2 P46087 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase chr12 GO:1902531 Not Cancer Driver No 116 0.143 510 72 0.141 0
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:1902531 Not Cancer Driver No 59 0.123 391 41 0.105 0
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 GO:1902531 Not Cancer Driver No 94 0.186 255 53 0.208 1
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:1902531 Not Cancer Driver No 101 0.179 18 8 0.444 0
NPLOC4 NPLOC4 Q8TAT6 Nuclear protein localization protein 4 homolog chr17 GO:1902531 Not Cancer Driver No 78 0.128 47 8 0.17 0
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:1902531 Not Cancer Driver No 32 0.212 71 14 0.197 1
NPPC NPPC P23582 C-type natriuretic peptide chr2 GO:1902531 Not Cancer Driver No 10 0.079 82 6 0.073 0
NPR1 NPR1 P16066 Atrial natriuretic peptide receptor 1 chr1 GO:1902531 Not Cancer Driver No 141 0.133 78 16 0.205 0
NPR2 NPR2 P20594 Atrial natriuretic peptide receptor 2 chr9 GO:1902531 Not Cancer Driver No 144 0.138 89 18 0.202 20
NPRL2 NPRL2 Q8WTW4 GATOR complex protein NPRL2 chr3 GO:1902531 Compendium Yes 37 0.097 10 3 0.3 1
NPRL3_ENST00000611875 NPRL3 Q12980 GATOR complex protein NPRL3 chr16 GO:1902531 Not Cancer Driver No 45 0.079 158 22 0.139 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:1902531 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:1902531 Compendium Yes 146 0.158 211 31 0.147 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:1902531 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:1902531 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:1902531 Census, Compendium Yes 249 0.297 57 21 0.368 0
NUAK1 NUAK1 O60285 NUAK family SNF1-like kinase 1 chr12 GO:1902531 Not Cancer Driver No 142 0.215 357 77 0.216 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:1902531 Not Cancer Driver No 10 0.122 82 10 0.122 0
OASL OASL Q15646 2'-5'-oligoadenylate synthase-like protein chr12 GO:1902531 Not Cancer Driver No 76 0.148 8 4 0.5 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX GO:1902531 Not Cancer Driver No 156 0.149 89 16 0.18 2
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 GO:1902531 Not Cancer Driver No 114 0.119 131 17 0.13 60
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:1902531 Not Cancer Driver No 117 0.308 18 5 0.278 0
OR51E2_ENST00000641638 OR51E2 Q9H255 Olfactory receptor 51E2 chr11 GO:1902531 Not Cancer Driver No 108 0.338 0 0 0.0 0
OSM OSM P13725 Oncostatin-M chr22 GO:1902531 Not Cancer Driver No 43 0.171 114 24 0.211 0
OTUD3 OTUD3 Q5T2D3 OTU domain-containing protein 3 chr1 GO:1902531 Not Cancer Driver No 43 0.108 280 25 0.089 0
OTUD5 OTUD5 Q96G74 OTU domain-containing protein 5 chrX GO:1902531 Not Cancer Driver No 55 0.096 430 39 0.091 4
P2RX2_ENST00000643471 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 GO:1902531 Not Cancer Driver No 62 0.132 104 13 0.125 2
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:1902531 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:1902531 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX5 P2RX5 Q93086 P2X purinoceptor 5 chr17 GO:1902531 Not Cancer Driver No 58 0.137 73 14 0.192 0
P2RY10 P2RY10 O00398 Putative P2Y purinoceptor 10 chrX GO:1902531 Not Cancer Driver No 113 0.333 0 0 0.0 0
P2RY8 P2RY8 Q86VZ1 P2Y purinoceptor 8 chrX GO:1902531 Census, Compendium Yes 126 0.351 23 5 0.217 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 GO:1902531 Not Cancer Driver No 61 0.12 79 15 0.19 1
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:1902531 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAK1IP1 PAK1IP1 Q9NWT1 p21-activated protein kinase-interacting protein 1 chr6 GO:1902531 Not Cancer Driver No 38 0.097 83 6 0.072 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:1902531 Not Cancer Driver No 57 0.105 299 30 0.1 2
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:1902531 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:1902531 Not Cancer Driver No 119 0.117 320 34 0.106 0
PBK_ENST00000301905 PBK Q96KB5 Lymphokine-activated killer T-cell-originated protein kinase chr8 GO:1902531 Not Cancer Driver No 23 0.071 92 6 0.065 0
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:1902531 Not Cancer Driver No 46 0.115 13 5 0.385 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 GO:1902531 Not Cancer Driver No 57 0.122 187 32 0.171 0
PDCD6 PDCD6 O75340 Programmed cell death protein 6 chr5 GO:1902531 Not Cancer Driver No 21 0.11 24 1 0.042 0
PDE10A_ENST00000366882 PDE10A Q9Y233 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A chr6 GO:1902531 Not Cancer Driver No 198 0.254 79 21 0.266 4
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 GO:1902531 Not Cancer Driver No 137 0.146 99 7 0.071 0
PDE4A PDE4A P27815 cAMP-specific 3',5'-cyclic phosphodiesterase 4A chr19 GO:1902531 Not Cancer Driver No 123 0.139 559 67 0.12 0
PDE5A PDE5A O76074 cGMP-specific 3',5'-cyclic phosphodiesterase chr4 GO:1902531 Not Cancer Driver No 113 0.129 163 23 0.141 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:1902531 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:1902531 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:1902531 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:1902531 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:1902531 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:1902531 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDK2 PDK2 Q15119 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial chr17 GO:1902531 Not Cancer Driver No 45 0.111 35 4 0.114 0
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:1902531 Not Cancer Driver No 32 0.113 238 23 0.097 0
PDZD3_ENST00000531114 PDZD3 Q86UT5 Na(+)/H(+) exchange regulatory cofactor NHE-RF4 chr11 GO:1902531 Not Cancer Driver No 58 0.102 199 19 0.095 0
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:1902531 Census Yes 160 0.124 948 116 0.122 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:1902531 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHLDA3 PHLDA3 Q9Y5J5 Pleckstrin homology-like domain family A member 3 chr1 GO:1902531 Not Cancer Driver No 20 0.157 0 0 0.0 0
PHLPP1 PHLPP1 O60346 PH domain leucine-rich repeat-containing protein phosphatase 1 chr18 GO:1902531 Not Cancer Driver No 134 0.078 744 29 0.039 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 GO:1902531 Not Cancer Driver No 58 0.114 142 23 0.162 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:1902531 Not Cancer Driver No 30 0.103 157 13 0.083 0
PIK3AP1 PIK3AP1 Q6ZUJ8 Phosphoinositide 3-kinase adapter protein 1 chr10 GO:1902531 Not Cancer Driver No 141 0.175 406 81 0.2 0
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:1902531 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:1902531 Not Cancer Driver No 318 0.289 121 39 0.322 0
PIK3IP1 PIK3IP1 Q96FE7 Phosphoinositide-3-kinase-interacting protein 1 chr22 GO:1902531 Not Cancer Driver No 27 0.103 128 13 0.102 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:1902531 Not Cancer Driver No 17 0.104 115 12 0.104 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:1902531 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP4P1_ENST00000250489 PIP4P1 Q86T03 Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase chr14 GO:1902531 Not Cancer Driver No 36 0.13 78 4 0.051 0
PJA2 PJA2 O43164 E3 ubiquitin-protein ligase Praja-2 chr5 GO:1902531 Not Cancer Driver No 80 0.113 598 66 0.11 0
PKHD1 PKHD1 P08F94 Fibrocystin chr6 GO:1902531 Not Cancer Driver No 778 0.191 413 81 0.196 93
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:1902531 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLA2R1 PLA2R1 Q13018 Secretory phospholipase A2 receptor chr2 GO:1902531 Not Cancer Driver No 202 0.138 39 2 0.051 0
PLAGL2 PLAGL2 Q9UPG8 Zinc finger protein PLAGL2 chr20 GO:1902531 Not Cancer Driver No 62 0.125 204 29 0.142 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:1902531 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLEK PLEK P08567 Pleckstrin chr2 GO:1902531 Not Cancer Driver No 81 0.231 39 9 0.231 0
PLEKHA1 PLEKHA1 Q9HB21 Pleckstrin homology domain-containing family A member 1 chr10 GO:1902531 Not Cancer Driver No 61 0.151 191 32 0.168 0
PLEKHF1 PLEKHF1 Q96S99 Pleckstrin homology domain-containing family F member 1 chr19 GO:1902531 Not Cancer Driver No 30 0.108 65 10 0.154 0
PLGLB2 PLGLB2 Q02325 Plasminogen-like protein B chr2 GO:1902531 Not Cancer Driver No 2 0.021 0 0 0.0 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:1902531 Not Cancer Driver No 75 0.116 202 15 0.074 0
PLXNB1_ENST00000296440 PLXNB1 O43157 Plexin-B1 chr3 GO:1902531 Not Cancer Driver No 228 0.107 684 67 0.098 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:1902531 Not Cancer Driver No 2 0.037 23 1 0.043 0
PML PML P29590 Protein PML chr15 GO:1902531 Census, Compendium Yes 112 0.127 312 34 0.109 0
POMC POMC P01189 Pro-opiomelanocortin chr2 GO:1902531 Not Cancer Driver No 50 0.187 198 38 0.192 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:1902531 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:1902531 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:1902531 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPM1A_ENST00000395076 PPM1A P35813 Protein phosphatase 1A chr14 GO:1902531 Not Cancer Driver No 60 0.157 134 24 0.179 0
PPM1B PPM1B O75688 Protein phosphatase 1B chr2 GO:1902531 Not Cancer Driver No 65 0.136 243 31 0.128 0
PPP1R10 PPP1R10 Q96QC0 Serine/threonine-protein phosphatase 1 regulatory subunit 10 chr6 GO:1902531 Not Cancer Driver No 114 0.121 798 100 0.125 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 GO:1902531 Not Cancer Driver No 41 0.133 12 1 0.083 8
PRAG1_ENST00000622241 PRAG1 Q86YV5 Inactive tyrosine-protein kinase PRAG1 chr8 GO:1902531 Not Cancer Driver No 193 0.137 988 150 0.152 0
PRAP1 PRAP1 Q96NZ9 Proline-rich acidic protein 1 chr10 GO:1902531 Not Cancer Driver No 14 0.093 124 13 0.105 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:1902531 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRKRA PRKRA O75569 Interferon-inducible double-stranded RNA-dependent protein kinase activator A chr2 GO:1902531 Not Cancer Driver No 41 0.131 104 12 0.115 1
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:1902531 Not Cancer Driver No 50 0.135 18 1 0.056 0
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:1902531 Not Cancer Driver No 83 0.13 72 6 0.083 0
PRMT6 PRMT6 Q96LA8 Protein arginine N-methyltransferase 6 chr1 GO:1902531 Not Cancer Driver No 43 0.115 71 7 0.099 0
PRNP PRNP P04156 Major prion protein chr20 GO:1902531 Not Cancer Driver No 36 0.142 115 7 0.061 18
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:1902531 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRR5L PRR5L Q6MZQ0 Proline-rich protein 5-like chr11 GO:1902531 Not Cancer Driver No 57 0.155 108 12 0.111 0
PRR5_ENST00000336985 PRR5 P85299 Proline-rich protein 5 chr22 GO:1902531 Not Cancer Driver No 50 0.129 173 22 0.127 0
PSCA PSCA O43653 Prostate stem cell antigen chr8 GO:1902531 Not Cancer Driver No 9 0.079 0 0 0.0 0
PSD PSD A5PKW4 PH and SEC7 domain-containing protein 1 chr10 GO:1902531 Not Cancer Driver No 173 0.169 714 130 0.182 0
PSD2 PSD2 Q9BQI7 PH and SEC7 domain-containing protein 2 chr5 GO:1902531 Not Cancer Driver No 155 0.201 398 87 0.219 0
PSD3_ENST00000440756 PSD3 Q9NYI0 PH and SEC7 domain-containing protein 3 chr8 GO:1902531 Not Cancer Driver No 146 0.139 645 94 0.146 0
PSD4 PSD4 Q8NDX1 PH and SEC7 domain-containing protein 4 chr2 GO:1902531 Not Cancer Driver No 157 0.149 739 103 0.139 0
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:1902531 Not Cancer Driver No 20 0.088 53 5 0.094 0
PTBP1_ENST00000349038 PTBP1 P26599 Polypyrimidine tract-binding protein 1 chr19 GO:1902531 Not Cancer Driver No 74 0.139 154 17 0.11 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:1902531 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:1902531 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:1902531 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:1902531 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:1902531 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:1902531 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:1902531 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:1902531 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:1902531 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:1902531 Not Cancer Driver No 184 0.138 401 61 0.152 0
PTPRR PTPRR Q15256 Receptor-type tyrosine-protein phosphatase R chr12 GO:1902531 Not Cancer Driver No 172 0.262 73 28 0.384 0
PTTG1IP PTTG1IP P53801 Pituitary tumor-transforming gene 1 protein-interacting protein chr21 GO:1902531 Not Cancer Driver No 23 0.128 30 9 0.3 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 GO:1902531 Not Cancer Driver No 150 0.126 640 77 0.12 3
PUM2_ENST00000403432 PUM2 Q8TB72 Pumilio homolog 2 chr2 GO:1902531 Not Cancer Driver No 132 0.124 575 83 0.144 0
PYDC2 PYDC2 Q56P42 Pyrin domain-containing protein 2 chr3 GO:1902531 Not Cancer Driver No 20 0.206 26 5 0.192 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 GO:1902531 Not Cancer Driver No 174 0.354 291 99 0.34 0
QARS QARS1 P47897 Glutamine--tRNA ligase chr3 GO:1902531 Not Cancer Driver No 101 0.13 106 16 0.151 4
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:1902531 Census, Compendium Yes 66 0.344 2 1 0.5 6
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:1902531 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAD9A RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:1902531 Not Cancer Driver No 34 0.087 135 7 0.052 0
RALBP1 RALBP1 Q15311 RalA-binding protein 1 chr18 GO:1902531 Not Cancer Driver No 65 0.099 381 46 0.121 0
RALGPS1 RALGPS1 Q5JS13 Ras-specific guanine nucleotide-releasing factor RalGPS1 chr9 GO:1902531 Not Cancer Driver No 62 0.111 219 26 0.119 0
RALGPS2 RALGPS2 Q86X27 Ras-specific guanine nucleotide-releasing factor RalGPS2 chr1 GO:1902531 Not Cancer Driver No 83 0.142 183 23 0.126 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:1902531 Not Cancer Driver No 30 0.203 0 0 0.0 0
RANBP9 RANBP9 Q96S59 Ran-binding protein 9 chr6 GO:1902531 Not Cancer Driver No 73 0.1 413 30 0.073 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:1902531 Not Cancer Driver No 216 0.144 803 116 0.144 0
RASGRF1 RASGRF1 Q13972 Ras-specific guanine nucleotide-releasing factor 1 chr15 GO:1902531 Not Cancer Driver No 226 0.178 332 64 0.193 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:1902531 Not Cancer Driver No 96 0.12 191 12 0.063 1
RASIP1 RASIP1 Q5U651 Ras-interacting protein 1 chr19 GO:1902531 Not Cancer Driver No 73 0.076 505 48 0.095 0
RASSF2 RASSF2 P50749 Ras association domain-containing protein 2 chr20 GO:1902531 Not Cancer Driver No 90 0.276 126 44 0.349 0
RCAN1_ENST00000313806 RCAN1 P53805 Calcipressin-1 chr21 GO:1902531 Not Cancer Driver No 26 0.103 104 7 0.067 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 GO:1902531 Not Cancer Driver No 71 0.122 297 37 0.125 1
RELA RELA Q04206 Transcription factor p65 chr11 GO:1902531 Compendium Yes 75 0.136 400 48 0.12 0
RELL1_ENST00000314117 RELL1 Q8IUW5 RELT-like protein 1 chr4 GO:1902531 Not Cancer Driver No 19 0.07 201 11 0.055 0
RELL2 RELL2 Q8NC24 RELT-like protein 2 chr5 GO:1902531 Not Cancer Driver No 39 0.129 259 37 0.143 0
RELN RELN P78509 Reelin chr7 GO:1902531 Not Cancer Driver No 761 0.22 107 19 0.178 7
RFFL_ENST00000394597 RFFL Q8WZ73 E3 ubiquitin-protein ligase rififylin chr17 GO:1902531 Not Cancer Driver No 50 0.138 150 21 0.14 0
RFWD3 RFWD3 Q6PCD5 E3 ubiquitin-protein ligase RFWD3 chr16 GO:1902531 Census Yes 68 0.088 318 30 0.094 1
RGL2 RGL2 O15211 Ral guanine nucleotide dissociation stimulator-like 2 chr6 GO:1902531 Not Cancer Driver No 87 0.112 461 51 0.111 0
RGN RGN Q15493 Regucalcin chrX GO:1902531 Not Cancer Driver No 38 0.127 14 3 0.214 0
RGS14 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:1902531 Not Cancer Driver No 57 0.101 309 37 0.12 0
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:1902531 Not Cancer Driver No 58 0.112 225 21 0.093 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:1902531 Not Cancer Driver No 66 0.127 295 39 0.132 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:1902531 Not Cancer Driver No 131 0.123 421 76 0.181 0
RIT2 RIT2 Q99578 GTP-binding protein Rit2 chr18 GO:1902531 Not Cancer Driver No 74 0.341 29 11 0.379 0
RNASEH2B RNASEH2B Q5TBB1 Ribonuclease H2 subunit B chr13 GO:1902531 Not Cancer Driver No 34 0.109 84 9 0.107 14
RNF125 RNF125 Q96EQ8 E3 ubiquitin-protein ligase RNF125 chr18 GO:1902531 Not Cancer Driver No 35 0.151 26 1 0.038 3
RNF152 RNF152 Q8N8N0 E3 ubiquitin-protein ligase RNF152 chr18 GO:1902531 Not Cancer Driver No 61 0.3 34 11 0.324 0
RNF183_ENST00000297894 RNF183 Q96D59 E3 ubiquitin-protein ligase RNF183 chr9 GO:1902531 Not Cancer Driver No 22 0.115 29 1 0.034 0
RNF34_ENST00000361234 RNF34 Q969K3 E3 ubiquitin-protein ligase RNF34 chr12 GO:1902531 Not Cancer Driver No 30 0.081 112 7 0.062 0
ROBO1 ROBO1 Q9Y6N7 Roundabout homolog 1 chr3 GO:1902531 Not Cancer Driver No 353 0.214 1122 234 0.209 0
ROR1 ROR1 Q01973 Inactive tyrosine-protein kinase transmembrane receptor ROR1 chr1 GO:1902531 Not Cancer Driver No 144 0.154 280 43 0.154 1
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:1902531 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 GO:1902531 Not Cancer Driver No 28 0.104 114 16 0.14 0
RPF2 RPF2 Q9H7B2 Ribosome production factor 2 homolog chr6 GO:1902531 Not Cancer Driver No 37 0.121 92 9 0.098 0
RPL11 RPL11 P62913 60S ribosomal protein L11 chr1 GO:1902531 Not Cancer Driver No 27 0.152 12 1 0.083 1
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 GO:1902531 Not Cancer Driver No 14 0.1 29 4 0.138 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:1902531 Not Cancer Driver No 16 0.11 114 13 0.114 0
RPL37 RPL37 P61927 60S ribosomal protein L37 chr5 GO:1902531 Not Cancer Driver No 12 0.124 83 10 0.12 0
RPL5_ENST00000370321 RPL5 P46777 60S ribosomal protein L5 chr1 GO:1902531 Census Yes 57 0.192 96 17 0.177 2
RPS15_ENST00000592588 RPS15 P62841 40S ribosomal protein S15 chr19 GO:1902531 Not Cancer Driver No 13 0.09 59 7 0.119 0
RPS20_ENST00000521262 RPS20 P60866 40S ribosomal protein S20 chr8 GO:1902531 Not Cancer Driver No 18 0.151 53 8 0.151 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:1902531 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS6KA6_ENST00000262752 RPS6KA6 Q9UK32 Ribosomal protein S6 kinase alpha-6 chrX GO:1902531 Not Cancer Driver No 180 0.242 136 36 0.265 0
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 GO:1902531 Not Cancer Driver No 29 0.149 39 7 0.179 0
RRAGA RRAGA Q7L523 Ras-related GTP-binding protein A chr9 GO:1902531 Not Cancer Driver No 30 0.096 0 0 0.0 0
RRAGB RRAGB Q5VZM2 Ras-related GTP-binding protein B chrX GO:1902531 Not Cancer Driver No 67 0.179 37 5 0.135 0
RRAGC RRAGC Q9HB90 Ras-related GTP-binding protein C chr1 GO:1902531 Compendium Yes 29 0.073 61 1 0.016 0
RRAGD RRAGD Q9NQL2 Ras-related GTP-binding protein D chr6 GO:1902531 Not Cancer Driver No 42 0.105 83 5 0.06 0
RRM2B RRM2B Q7LG56 Ribonucleoside-diphosphate reductase subunit M2 B chr8 GO:1902531 Not Cancer Driver No 46 0.131 32 5 0.156 9
RRN3 RRN3 Q9NYV6 RNA polymerase I-specific transcription initiation factor RRN3 chr16 GO:1902531 Not Cancer Driver No 66 0.101 115 15 0.13 0
RRS1 RRS1 Q15050 Ribosome biogenesis regulatory protein homolog chr8 GO:1902531 Not Cancer Driver No 23 0.063 315 18 0.057 0
RTN4R RTN4R Q9BZR6 Reticulon-4 receptor chr22 GO:1902531 Not Cancer Driver No 38 0.08 148 17 0.115 5
RUNDC3A RUNDC3A Q59EK9 RUN domain-containing protein 3A chr17 GO:1902531 Not Cancer Driver No 39 0.087 175 8 0.046 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 GO:1902531 Not Cancer Driver No 22 0.237 8 4 0.5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:1902531 Not Cancer Driver No 18 0.158 76 7 0.092 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:1902531 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SCAI_ENST00000336505 SCAI Q8N9R8 Protein SCAI chr9 GO:1902531 Not Cancer Driver No 95 0.157 117 13 0.111 0
SCT SCT P09683 Secretin chr11 GO:1902531 Not Cancer Driver No 4 0.033 71 3 0.042 0
SCTR SCTR P47872 Secretin receptor chr2 GO:1902531 Not Cancer Driver No 74 0.168 18 1 0.056 0
SEC14L1_ENST00000436233 SEC14L1 Q92503 SEC14-like protein 1 chr17 GO:1902531 Not Cancer Driver No 104 0.145 82 16 0.195 0
SEH1L_ENST00000262124 SEH1L Q96EE3 Nucleoporin SEH1 chr18 GO:1902531 Not Cancer Driver No 40 0.111 71 11 0.155 0
SELENOK SELENOK Q9Y6D0 Selenoprotein K chr3 GO:1902531 Not Cancer Driver No 10 0.106 47 6 0.128 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:1902531 Not Cancer Driver No 7 0.037 122 6 0.049 0
SELP SELP P16109 P-selectin chr1 GO:1902531 Not Cancer Driver No 226 0.272 14 2 0.143 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:1902531 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 GO:1902531 Not Cancer Driver No 136 0.132 456 72 0.158 0
SEPT4_ENST00000317268 SEPTIN4 O43236 Septin-4 chr17 GO:1902531 Not Cancer Driver No 61 0.128 220 31 0.141 0
SERINC3_ENST00000255175 SERINC3 Q13530 Serine incorporator 3 chr20 GO:1902531 Not Cancer Driver No 73 0.154 38 9 0.237 0
SERPINA12 SERPINA12 Q8IW75 Serpin A12 chr14 GO:1902531 Not Cancer Driver No 90 0.217 22 3 0.136 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 GO:1902531 Not Cancer Driver No 142 0.364 47 28 0.596 0
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 GO:1902531 Not Cancer Driver No 62 0.156 0 0 0.0 0
SESN1_ENST00000356644 SESN1 Q9Y6P5 Sestrin-1 chr6 GO:1902531 Not Cancer Driver No 45 0.091 48 4 0.083 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:1902531 Not Cancer Driver No 74 0.154 147 26 0.177 0
SESN3 SESN3 P58005 Sestrin-3 chr11 GO:1902531 Not Cancer Driver No 84 0.171 44 4 0.091 0
SETD9 SETD9 Q8NE22 SET domain-containing protein 9 chr5 GO:1902531 Not Cancer Driver No 28 0.094 4 1 0.25 0
SEZ6 SEZ6 Q53EL9 Seizure protein 6 homolog chr17 GO:1902531 Not Cancer Driver No 120 0.121 345 54 0.157 0
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 GO:1902531 Census Yes 59 0.083 595 48 0.081 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:1902531 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:1902531 Not Cancer Driver No 47 0.159 1 0 0.0 0
SFRP5 SFRP5 Q5T4F7 Secreted frizzled-related protein 5 chr10 GO:1902531 Not Cancer Driver No 26 0.082 7 3 0.429 0
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 GO:1902531 Census, Compendium Yes 58 0.135 86 16 0.186 0
SGSM3 SGSM3 Q96HU1 Small G protein signaling modulator 3 chr22 GO:1902531 Not Cancer Driver No 83 0.111 77 9 0.117 0
SH2B3 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 GO:1902531 Census, Compendium Yes 48 0.083 333 19 0.057 0
SH3BP1 SH3BP1 Q9Y3L3 SH3 domain-binding protein 1 chr22 GO:1902531 Not Cancer Driver No 57 0.081 430 31 0.072 0
SH3RF2 SH3RF2 Q8TEC5 E3 ubiquitin-protein ligase SH3RF2 chr5 GO:1902531 Not Cancer Driver No 151 0.207 455 101 0.222 0
SHANK2_ENST00000601538 SHANK2 Q9UPX8 SH3 and multiple ankyrin repeat domains protein 2 chr11 GO:1902531 Not Cancer Driver No 303 0.164 1379 262 0.19 0
SIAH1_ENST00000394725 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 GO:1902531 Not Cancer Driver No 35 0.124 28 2 0.071 5
SIK3 SIK3 Q9Y2K2 Serine/threonine-protein kinase SIK3 chr11 GO:1902531 Not Cancer Driver No 143 0.108 964 107 0.111 1
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:1902531 Census, Compendium Yes 96 0.19 281 51 0.181 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:1902531 Not Cancer Driver No 70 0.094 435 31 0.071 0
SKIL_ENST00000259119 SKIL P12757 Ski-like protein chr3 GO:1902531 Not Cancer Driver No 77 0.113 356 32 0.09 0
SLA2 SLA2 Q9H6Q3 Src-like-adapter 2 chr20 GO:1902531 Not Cancer Driver No 32 0.123 43 9 0.209 0
SLC15A2 SLC15A2 Q16348 Solute carrier family 15 member 2 chr3 GO:1902531 Not Cancer Driver No 153 0.21 37 7 0.189 0
SLC15A3 SLC15A3 Q8IY34 Solute carrier family 15 member 3 chr11 GO:1902531 Not Cancer Driver No 63 0.108 43 1 0.023 0
SLC15A4 SLC15A4 Q8N697 Solute carrier family 15 member 4 chr12 GO:1902531 Not Cancer Driver No 66 0.114 23 4 0.174 0
SLC24A4 SLC24A4 Q8NFF2 Sodium/potassium/calcium exchanger 4 chr14 GO:1902531 Not Cancer Driver No 121 0.195 85 14 0.165 2
SLC46A2 SLC46A2 Q9BY10 Thymic stromal cotransporter homolog chr9 GO:1902531 Not Cancer Driver No 45 0.095 36 3 0.083 0
SLC8A2 SLC8A2 Q9UPR5 Sodium/calcium exchanger 2 chr19 GO:1902531 Not Cancer Driver No 117 0.127 143 19 0.133 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:1902531 Not Cancer Driver No 89 0.109 251 29 0.116 1
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:1902531 Not Cancer Driver No 19 0.053 318 16 0.05 4
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:1902531 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMCR8 SMCR8 Q8TEV9 Guanine nucleotide exchange protein SMCR8 chr17 GO:1902531 Not Cancer Driver No 107 0.114 357 38 0.106 0
SMYD2 SMYD2 Q9NRG4 N-lysine methyltransferase SMYD2 chr1 GO:1902531 Not Cancer Driver No 42 0.097 12 0 0.0 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:1902531 Not Cancer Driver No 52 0.197 97 11 0.113 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:1902531 Not Cancer Driver No 52 0.194 52 9 0.173 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:1902531 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:1902531 Not Cancer Driver No 32 0.144 25 5 0.2 0
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:1902531 Compendium Yes 197 0.148 458 62 0.135 38
SOS2 SOS2 Q07890 Son of sevenless homolog 2 chr14 GO:1902531 Not Cancer Driver No 173 0.13 362 54 0.149 2
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:1902531 Not Cancer Driver No 61 0.138 368 53 0.144 2
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:1902531 Not Cancer Driver No 28 0.059 400 24 0.06 4
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:1902531 Compendium Yes 86 0.169 495 82 0.166 18
SPATC1L SPATC1L Q9H0A9 Speriolin-like protein chr21 GO:1902531 Not Cancer Driver No 30 0.088 179 11 0.061 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:1902531 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:1902531 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:1902531 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPINK1 SPINK1 P00995 Serine protease inhibitor Kazal-type 1 chr5 GO:1902531 Not Cancer Driver No 14 0.177 0 0 0.0 3
SPPL3 SPPL3 Q8TCT6 Signal peptide peptidase-like 3 chr12 GO:1902531 Not Cancer Driver No 45 0.117 23 0 0.0 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:1902531 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 GO:1902531 Not Cancer Driver No 73 0.175 228 43 0.189 0
SPRED3_ENST00000586301 SPRED3 Q2MJR0 Sprouty-related, EVH1 domain-containing protein 3 chr19 GO:1902531 Not Cancer Driver No 31 0.076 207 15 0.072 0
SPRY1 SPRY1 O43609 Protein sprouty homolog 1 chr4 GO:1902531 Not Cancer Driver No 46 0.144 168 26 0.155 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:1902531 Not Cancer Driver No 46 0.146 169 29 0.172 1
SPRY3 SPRY3 O43610 Protein sprouty homolog 3 chrX GO:1902531 Not Cancer Driver No 96 0.333 135 40 0.296 0
SPRY4_ENST00000434127 SPRY4 Q9C004 Protein sprouty homolog 4 chr5 GO:1902531 Not Cancer Driver No 34 0.114 134 20 0.149 7
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:1902531 Census Yes 53 0.099 130 11 0.085 1
SSX2IP SSX2IP Q9Y2D8 Afadin- and alpha-actinin-binding protein chr1 GO:1902531 Not Cancer Driver No 82 0.134 265 31 0.117 0
STAMBP_ENST00000339566 STAMBP O95630 STAM-binding protein chr2 GO:1902531 Not Cancer Driver No 51 0.12 139 16 0.115 6
STIMATE STIMATE Q86TL2 Store-operated calcium entry regulator STIMATE chr3 GO:1902531 Not Cancer Driver No 27 0.092 61 4 0.066 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:1902531 Census, Compendium Yes 75 0.173 135 14 0.104 9
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:1902531 Not Cancer Driver No 64 0.117 182 19 0.104 0
STMN1_ENST00000357865 STMN1 P16949 Stathmin chr1 GO:1902531 Not Cancer Driver No 15 0.101 149 15 0.101 0
STMN3 STMN3 Q9NZ72 Stathmin-3 chr20 GO:1902531 Not Cancer Driver No 26 0.144 152 25 0.164 0
STYXL1_ENST00000359697 STYXL1 Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 chr7 GO:1902531 Not Cancer Driver No 55 0.176 18 3 0.167 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:1902531 Census Yes 96 0.151 131 27 0.206 5
SYNJ2BP SYNJ2BP P57105 Synaptojanin-2-binding protein chr14 GO:1902531 Not Cancer Driver No 27 0.186 12 4 0.333 0
SYNPO2L SYNPO2L Q9H987 Synaptopodin 2-like protein chr10 GO:1902531 Not Cancer Driver No 103 0.105 950 99 0.104 0
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 GO:1902531 Not Cancer Driver No 63 0.102 284 32 0.113 0
SZT2_ENST00000634258 SZT2 Q5T011 KICSTOR complex protein SZT2 chr1 GO:1902531 Not Cancer Driver No 381 0.111 1292 161 0.125 1
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:1902531 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 GO:1902531 Not Cancer Driver No 25 0.095 203 19 0.094 0
TAF9B TAF9B Q9HBM6 Transcription initiation factor TFIID subunit 9B chrX GO:1902531 Not Cancer Driver No 48 0.191 189 34 0.18 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:1902531 Not Cancer Driver No 123 0.137 494 64 0.13 0
TBC1D10C TBC1D10C Q8IV04 Carabin chr11 GO:1902531 Not Cancer Driver No 58 0.13 192 32 0.167 0
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:1902531 Not Cancer Driver No 21 0.198 33 7 0.212 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:1902531 Not Cancer Driver No 219 0.195 126 22 0.175 10
TELO2 TELO2 Q9Y4R8 Telomere length regulation protein TEL2 homolog chr16 GO:1902531 Not Cancer Driver No 113 0.135 154 23 0.149 5
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:1902531 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGM2 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 GO:1902531 Not Cancer Driver No 123 0.179 107 26 0.243 0
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:1902531 Not Cancer Driver No 188 0.161 320 58 0.181 0
THOC1 THOC1 Q96FV9 THO complex subunit 1 chr18 GO:1902531 Not Cancer Driver No 55 0.084 280 26 0.093 0
THOC5_ENST00000397872 THOC5 Q13769 THO complex subunit 5 homolog chr22 GO:1902531 Not Cancer Driver No 88 0.129 173 25 0.145 0
TIAL1_ENST00000436547 TIAL1 Q01085 Nucleolysin TIAR chr10 GO:1902531 Not Cancer Driver No 45 0.12 122 12 0.098 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:1902531 Not Cancer Driver No 43 0.204 3 1 0.333 5
TKFC TKFC Q3LXA3 Triokinase/FMN cyclase chr11 GO:1902531 Not Cancer Driver No 66 0.115 91 14 0.154 2
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:1902531 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:1902531 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:1902531 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMBIM4_ENST00000358230 TMBIM4 Q9HC24 Protein lifeguard 4 chr12 GO:1902531 Not Cancer Driver No 36 0.151 3 0 0.0 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:1902531 Not Cancer Driver No 16 0.068 3 0 0.0 0
TMEM100 TMEM100 Q9NV29 Transmembrane protein 100 chr17 GO:1902531 Not Cancer Driver No 29 0.216 0 0 0.0 0
TMEM161A TMEM161A Q9NX61 Transmembrane protein 161A chr19 GO:1902531 Not Cancer Driver No 49 0.102 22 8 0.364 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:1902531 Census Yes 7 0.159 44 7 0.159 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:1902531 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP1 TNFAIP1 Q13829 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 chr17 GO:1902531 Not Cancer Driver No 35 0.111 39 5 0.128 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:1902531 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:1902531 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:1902531 Not Cancer Driver No 52 0.164 56 1 0.018 1
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 GO:1902531 Not Cancer Driver No 85 0.134 625 83 0.133 0
TP53RK TP53RK Q96S44 EKC/KEOPS complex subunit TP53RK chr20 GO:1902531 Not Cancer Driver No 20 0.079 51 2 0.039 3
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:1902531 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPR TPR P12270 Nucleoprotein TPR chr1 GO:1902531 Census Yes 311 0.132 1990 266 0.134 0
TPT1_ENST00000530705 TPT1 P13693 Translationally-controlled tumor protein chr13 GO:1902531 Not Cancer Driver No 17 0.099 43 6 0.14 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:1902531 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:1902531 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 GO:1902531 Not Cancer Driver No 74 0.105 110 11 0.1 0
TRAT1 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 GO:1902531 Not Cancer Driver No 86 0.462 129 67 0.519 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:1902531 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIAP1 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 GO:1902531 Not Cancer Driver No 9 0.118 20 1 0.05 0
TRIM15 TRIM15 Q9C019 Tripartite motif-containing protein 15 chr6 GO:1902531 Not Cancer Driver No 69 0.148 79 11 0.139 0
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 GO:1902531 Census, Compendium Yes 120 0.114 537 61 0.114 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:1902531 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIM40_ENST00000376724 TRIM40 Q6P9F5 E3 ubiquitin ligase TRIM40 chr6 GO:1902531 Not Cancer Driver No 44 0.171 84 12 0.143 0
TSC2 TSC2 P49815 Tuberin chr16 GO:1902531 Census, Compendium Yes 192 0.106 563 50 0.089 53
TSPAN6 TSPAN6 O43657 Tetraspanin-6 chrX GO:1902531 Not Cancer Driver No 34 0.139 0 0 0.0 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:1902531 Not Cancer Driver No 23 0.114 132 11 0.083 7
TXNDC12 TXNDC12 O95881 Thioredoxin domain-containing protein 12 chr1 GO:1902531 Not Cancer Driver No 21 0.122 44 6 0.136 0
UACA UACA Q9BZF9 Uveal autoantigen with coiled-coil domains and ankyrin repeats chr15 GO:1902531 Not Cancer Driver No 177 0.125 863 101 0.117 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 GO:1902531 Not Cancer Driver No 20 0.087 102 8 0.078 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:1902531 Not Cancer Driver No 141 0.161 136 22 0.162 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:1902531 Not Cancer Driver No 64 0.109 543 58 0.107 0
UCN UCN P55089 Urocortin chr2 GO:1902531 Not Cancer Driver No 7 0.056 61 4 0.066 0
UFD1 UFD1 Q92890 Ubiquitin recognition factor in ER-associated degradation protein 1 chr22 GO:1902531 Not Cancer Driver No 26 0.085 100 7 0.07 0
ULK4 ULK4 Q96C45 Serine/threonine-protein kinase ULK4 chr3 GO:1902531 Not Cancer Driver No 162 0.127 180 33 0.183 0
UNC5B UNC5B Q8IZJ1 Netrin receptor UNC5B chr10 GO:1902531 Not Cancer Driver No 155 0.164 117 20 0.171 0
URB2 URB2 Q14146 Unhealthy ribosome biogenesis protein 2 homolog chr1 GO:1902531 Not Cancer Driver No 186 0.122 18 2 0.111 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 GO:1902531 Not Cancer Driver No 136 0.139 259 39 0.151 0
USP17L2 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 GO:1902531 Not Cancer Driver No 105 0.198 201 54 0.269 0
USP2 USP2 O75604 Ubiquitin carboxyl-terminal hydrolase 2 chr11 GO:1902531 Not Cancer Driver No 88 0.145 213 39 0.183 0
USP44_ENST00000537435 USP44 Q9H0E7 Ubiquitin carboxyl-terminal hydrolase 44 chr12 GO:1902531 Census, Compendium Yes 94 0.132 114 14 0.123 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 GO:1902531 Not Cancer Driver No 137 0.1 425 39 0.092 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:1902531 Not Cancer Driver No 170 0.154 215 45 0.209 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:1902531 Not Cancer Driver No 27 0.116 41 7 0.171 0
VGLL4_ENST00000273038 VGLL4 Q14135 Transcription cofactor vestigial-like protein 4 chr3 GO:1902531 Not Cancer Driver No 40 0.138 276 38 0.138 0
VNN1 VNN1 O95497 Pantetheinase chr6 GO:1902531 Not Cancer Driver No 88 0.172 20 5 0.25 0
VRK3_ENST00000594948 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 GO:1902531 Not Cancer Driver No 65 0.137 180 18 0.1 0
WAC WAC Q9BTA9 WW domain-containing adapter protein with coiled-coil chr10 GO:1902531 Not Cancer Driver No 106 0.164 571 95 0.166 0
WDR76 WDR76 Q9H967 WD repeat-containing protein 76 chr15 GO:1902531 Not Cancer Driver No 60 0.096 288 33 0.115 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:1902531 Not Cancer Driver No 105 0.118 203 10 0.049 39
WNK2 WNK2 Q9Y3S1 Serine/threonine-protein kinase WNK2 chr9 GO:1902531 Census, Compendium Yes 223 0.097 1868 167 0.089 0
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:1902531 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT16 WNT16 Q9UBV4 Protein Wnt-16 chr7 GO:1902531 Not Cancer Driver No 59 0.162 28 9 0.321 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:1902531 Not Cancer Driver No 66 0.174 0 0 0.0 2
WTIP WTIP A6NIX2 Wilms tumor protein 1-interacting protein chr19 GO:1902531 Not Cancer Driver No 32 0.074 217 2 0.009 0
WWC1_ENST00000265293 WWC1 Q8IX03 Protein KIBRA chr5 GO:1902531 Not Cancer Driver No 147 0.132 550 81 0.147 0
WWC2 WWC2 Q6AWC2 Protein WWC2 chr4 GO:1902531 Not Cancer Driver No 120 0.101 654 79 0.121 0
WWC3 WWC3 Q9ULE0 Protein WWC3 chrX GO:1902531 Not Cancer Driver No 214 0.196 638 114 0.179 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:1902531 Not Cancer Driver No 19 0.073 169 9 0.053 0
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:1902531 Not Cancer Driver No 279 0.209 134 24 0.179 1
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX GO:1902531 Not Cancer Driver No 89 0.179 55 6 0.109 0
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 GO:1902531 Not Cancer Driver No 24 0.069 35 2 0.057 1
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:1902531 Not Cancer Driver No 49 0.132 359 47 0.131 0
YJU2 YJU2 Q9BW85 Splicing factor YJU2 chr19 GO:1902531 Not Cancer Driver No 29 0.09 233 13 0.056 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:1902531 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:1902531 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZCCHC3 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 GO:1902531 Not Cancer Driver No 28 0.069 160 1 0.006 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:1902531 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZMYND11 ZMYND11 Q15326 Zinc finger MYND domain-containing protein 11 chr10 GO:1902531 Not Cancer Driver No 71 0.118 184 26 0.141 0
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:1902531 Not Cancer Driver No 43 0.111 312 34 0.109 0
ZNF675 ZNF675 Q8TD23 Zinc finger protein 675 chr19 GO:1902531 Not Cancer Driver No 114 0.201 91 19 0.209 0