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Total number of protein in "GO:1902494" GO term:  783

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 GO:1902494 Not Cancer Driver No 84 0.168 28 5 0.179 1
ACTL6A ACTL6A O96019 Actin-like protein 6A chr3 GO:1902494 Not Cancer Driver No 61 0.142 74 15 0.203 0
ACTL6B ACTL6B O94805 Actin-like protein 6B chr7 GO:1902494 Not Cancer Driver No 77 0.181 108 19 0.176 3
ACTR6 ACTR6 Q9GZN1 Actin-related protein 6 chr12 GO:1902494 Not Cancer Driver No 48 0.121 17 4 0.235 0
ACVR1B_ENST00000257963 ACVR1B P36896 Activin receptor type-1B chr12 GO:1902494 Census Yes 114 0.226 0 0 0.0 0
ACVR1C ACVR1C Q8NER5 Activin receptor type-1C chr2 GO:1902494 Not Cancer Driver No 90 0.183 3 1 0.333 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:1902494 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:1902494 Census, Compendium Yes 98 0.191 56 6 0.107 0
ACVR2B ACVR2B Q13705 Activin receptor type-2B chr3 GO:1902494 Not Cancer Driver No 83 0.162 70 14 0.2 2
AEBP2 AEBP2 Q6ZN18 Zinc finger protein AEBP2 chr12 GO:1902494 Not Cancer Driver No 41 0.079 335 25 0.075 0
AFG3L2 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 GO:1902494 Not Cancer Driver No 72 0.09 162 10 0.062 22
AGL_ENST00000361915 AGL P35573 Glycogen debranching enzyme chr1 GO:1902494 Not Cancer Driver No 182 0.119 143 23 0.161 1
AGO1 AGO1 Q9UL18 Protein argonaute-1 chr1 GO:1902494 Not Cancer Driver No 126 0.147 87 11 0.126 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:1902494 Not Cancer Driver No 126 0.147 141 15 0.106 11
AGO3 AGO3 Q9H9G7 Protein argonaute-3 chr1 GO:1902494 Not Cancer Driver No 110 0.128 143 19 0.133 0
AGO4 AGO4 Q9HCK5 Protein argonaute-4 chr1 GO:1902494 Not Cancer Driver No 100 0.116 183 24 0.131 0
AMHR2 AMHR2 Q16671 Anti-Muellerian hormone type-2 receptor chr12 GO:1902494 Not Cancer Driver No 77 0.134 117 7 0.06 8
ANKRD39 ANKRD39 Q53RE8 Ankyrin repeat domain-containing protein 39 chr2 GO:1902494 Not Cancer Driver No 19 0.104 38 2 0.053 0
ANKRD9_ENST00000560748 ANKRD9 Q96BM1 Ankyrin repeat domain-containing protein 9 chr14 GO:1902494 Not Cancer Driver No 7 0.022 62 1 0.016 0
ANP32E ANP32E Q9BTT0 Acidic leucine-rich nuclear phosphoprotein 32 family member E chr1 GO:1902494 Not Cancer Driver No 40 0.149 135 18 0.133 0
APPBP2 APPBP2 Q92624 Amyloid protein-binding protein 2 chr17 GO:1902494 Not Cancer Driver No 61 0.104 10 0 0.0 0
AQR AQR O60306 RNA helicase aquarius chr15 GO:1902494 Not Cancer Driver No 201 0.135 297 31 0.104 0
ARID1A ARID1A O14497 AT-rich interactive domain-containing protein 1A chr1 GO:1902494 Census, Compendium Yes 275 0.12 1856 206 0.111 0
ARID1B_ENST00000350026 ARID1B Q8NFD5 AT-rich interactive domain-containing protein 1B chr6 GO:1902494 Census, Compendium Yes 251 0.108 1890 206 0.109 0
ASB4 ASB4 Q9Y574 Ankyrin repeat and SOCS box protein 4 chr7 GO:1902494 Not Cancer Driver No 82 0.192 19 1 0.053 0
ASB6 ASB6 Q9NWX5 Ankyrin repeat and SOCS box protein 6 chr9 GO:1902494 Not Cancer Driver No 35 0.083 31 3 0.097 0
ASH2L ASH2L Q9UBL3 Set1/Ash2 histone methyltransferase complex subunit ASH2 chr8 GO:1902494 Not Cancer Driver No 95 0.151 293 39 0.133 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:1902494 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:1902494 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATG101 ATG101 Q9BSB4 Autophagy-related protein 101 chr12 GO:1902494 Not Cancer Driver No 21 0.096 5 0 0.0 0
ATG12 ATG12 O94817 Ubiquitin-like protein ATG12 chr5 GO:1902494 Not Cancer Driver No 15 0.107 60 8 0.133 0
ATG13_ENST00000359513 ATG13 O75143 Autophagy-related protein 13 chr11 GO:1902494 Not Cancer Driver No 55 0.106 205 27 0.132 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 GO:1902494 Not Cancer Driver No 79 0.13 239 25 0.105 1
ATG16L2 ATG16L2 Q8NAA4 Protein Atg16l2 chr11 GO:1902494 Not Cancer Driver No 43 0.069 171 7 0.041 0
ATG3 ATG3 Q9NT62 Ubiquitin-like-conjugating enzyme ATG3 chr3 GO:1902494 Not Cancer Driver No 29 0.092 110 9 0.082 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 GO:1902494 Not Cancer Driver No 40 0.145 25 6 0.24 1
AUP1 AUP1 Q9Y679 Lipid droplet-regulating VLDL assembly factor AUP1 chr2 GO:1902494 Not Cancer Driver No 41 0.1 122 13 0.107 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:1902494 Census Yes 96 0.124 384 49 0.128 0
BAZ1A_ENST00000382422 BAZ1A Q9NRL2 Bromodomain adjacent to zinc finger domain protein 1A chr14 GO:1902494 Census Yes 156 0.1 752 65 0.086 0
BAZ1B_ENST00000404251 BAZ1B Q9UIG0 Tyrosine-protein kinase BAZ1B chr7 GO:1902494 Not Cancer Driver No 153 0.103 840 87 0.104 0
BCAS2 BCAS2 O75934 Pre-mRNA-splicing factor SPF27 chr1 GO:1902494 Not Cancer Driver No 30 0.133 55 5 0.091 0
BCCIP_ENST00000278100 BCCIP Q9P287 BRCA2 and CDKN1A-interacting protein chr10 GO:1902494 Not Cancer Driver No 35 0.111 99 16 0.162 0
BCKDHA BCKDHA P12694 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial chr19 GO:1902494 Not Cancer Driver No 53 0.119 121 18 0.149 11
BCKDHB BCKDHB P21953 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial chr6 GO:1902494 Not Cancer Driver No 47 0.12 23 3 0.13 5
BCKDK BCKDK O14874 [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial chr16 GO:1902494 Not Cancer Driver No 62 0.15 39 3 0.077 3
BCOR BCOR Q6W2J9 BCL-6 corepressor chrX GO:1902494 Census, Compendium Yes 291 0.166 1285 226 0.176 1
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:1902494 Not Cancer Driver No 45 0.1 190 19 0.1 0
BOD1 BOD1 Q96IK1 Biorientation of chromosomes in cell division protein 1 chr5 GO:1902494 Not Cancer Driver No 16 0.086 133 10 0.075 0
BOD1L1 BOD1L1 Q8NFC6 Biorientation of chromosomes in cell division protein 1-like 1 chr4 GO:1902494 Not Cancer Driver No 387 0.127 3023 384 0.127 0
BPTF_ENST00000321892 BPTF Q12830 Nucleosome-remodeling factor subunit BPTF chr17 GO:1902494 Not Cancer Driver No 309 0.101 2187 218 0.1 2
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:1902494 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 GO:1902494 Not Cancer Driver No 171 0.162 425 68 0.16 0
BRD8 BRD8 Q9H0E9 Bromodomain-containing protein 8 chr5 GO:1902494 Not Cancer Driver No 189 0.153 934 147 0.157 0
BRPF1_ENST00000457855 BRPF1 P55201 Peregrin chr3 GO:1902494 Not Cancer Driver No 148 0.122 753 95 0.126 2
BRPF3 BRPF3 Q9ULD4 Bromodomain and PHD finger-containing protein 3 chr6 GO:1902494 Not Cancer Driver No 143 0.119 633 74 0.117 0
BUD31 BUD31 P41223 Protein BUD31 homolog chr7 GO:1902494 Not Cancer Driver No 20 0.139 32 4 0.125 0
C17orf49_ENST00000439424 BAP18 Q8IXM2 Chromatin complexes subunit BAP18 chr17 GO:1902494 Not Cancer Driver No 16 0.093 123 13 0.106 0
C1D_ENST00000410067 C1D Q13901 Nuclear nucleic acid-binding protein C1D chr2 GO:1902494 Not Cancer Driver No 12 0.085 42 4 0.095 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:1902494 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:1902494 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:1902494 Not Cancer Driver No 17 0.114 115 10 0.087 3
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:1902494 Not Cancer Driver No 81 0.116 46 11 0.239 0
CAPNS1 CAPNS1 P04632 Calpain small subunit 1 chr19 GO:1902494 Not Cancer Driver No 30 0.112 58 5 0.086 0
CASC3 CASC3 O15234 Protein CASC3 chr17 GO:1902494 Not Cancer Driver No 84 0.119 700 83 0.119 0
CASP10_ENST00000272879 CASP10 Q92851 Caspase-10 chr2 GO:1902494 Not Cancer Driver No 57 0.109 126 17 0.135 3
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:1902494 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:1902494 Census Yes 49 0.118 71 7 0.099 0
CAT CAT P04040 Catalase chr11 GO:1902494 Not Cancer Driver No 70 0.133 176 18 0.102 0
CBLL1 CBLL1 Q75N03 E3 ubiquitin-protein ligase Hakai chr7 GO:1902494 Not Cancer Driver No 72 0.147 373 49 0.131 0
CCNA1 CCNA1 P78396 Cyclin-A1 chr13 GO:1902494 Not Cancer Driver No 112 0.241 82 21 0.256 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 GO:1902494 Not Cancer Driver No 45 0.104 186 19 0.102 0
CCNB1 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 GO:1902494 Not Cancer Driver No 49 0.113 145 14 0.097 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:1902494 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCND2 CCND2 P30279 G1/S-specific cyclin-D2 chr12 GO:1902494 Census, Compendium Yes 39 0.135 29 7 0.241 5
CCND3 CCND3 P30281 G1/S-specific cyclin-D3 chr6 GO:1902494 Census, Compendium Yes 29 0.099 46 8 0.174 0
CCNE1 CCNE1 P24864 G1/S-specific cyclin-E1 chr19 GO:1902494 Census Yes 63 0.154 142 26 0.183 0
CCNE2_ENST00000308108 CCNE2 O96020 G1/S-specific cyclin-E2 chr8 GO:1902494 Not Cancer Driver No 46 0.114 68 9 0.132 0
CCNH CCNH P51946 Cyclin-H chr5 GO:1902494 Not Cancer Driver No 40 0.124 28 4 0.143 0
CCNK CCNK O75909 Cyclin-K chr14 GO:1902494 Not Cancer Driver No 39 0.067 347 15 0.043 1
CCNO CCNO P22674 Cyclin-O chr5 GO:1902494 Not Cancer Driver No 18 0.051 101 3 0.03 2
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 GO:1902494 Not Cancer Driver No 85 0.117 495 61 0.123 0
CCNT2 CCNT2 O60583 Cyclin-T2 chr2 GO:1902494 Not Cancer Driver No 76 0.104 471 52 0.11 0
CCNY CCNY Q8ND76 Cyclin-Y chr10 GO:1902494 Not Cancer Driver No 38 0.111 94 6 0.064 0
CDC40 CDC40 O60508 Pre-mRNA-processing factor 17 chr6 GO:1902494 Not Cancer Driver No 79 0.136 214 27 0.126 1
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 GO:1902494 Not Cancer Driver No 100 0.125 618 77 0.125 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:1902494 Not Cancer Driver No 40 0.135 1 0 0.0 0
CDK12 CDK12 Q9NYV4 Cyclin-dependent kinase 12 chr17 GO:1902494 Census, Compendium Yes 225 0.151 1202 160 0.133 0
CDK13 CDK13 Q14004 Cyclin-dependent kinase 13 chr7 GO:1902494 Not Cancer Driver No 155 0.103 1138 99 0.087 6
CDK14 CDK14 O94921 Cyclin-dependent kinase 14 chr7 GO:1902494 Not Cancer Driver No 93 0.198 154 21 0.136 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:1902494 Not Cancer Driver No 24 0.081 0 0 0.0 0
CDK4 CDK4 P11802 Cyclin-dependent kinase 4 chr12 GO:1902494 Census, Compendium Yes 52 0.172 52 5 0.096 3
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:1902494 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:1902494 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5R2 CDK5R2 Q13319 Cyclin-dependent kinase 5 activator 2 chr2 GO:1902494 Not Cancer Driver No 14 0.038 204 5 0.025 0
CDK6 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 GO:1902494 Census Yes 40 0.123 24 3 0.125 1
CDK7 CDK7 P50613 Cyclin-dependent kinase 7 chr5 GO:1902494 Not Cancer Driver No 41 0.118 38 5 0.132 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 GO:1902494 Not Cancer Driver No 50 0.134 34 2 0.059 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:1902494 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 GO:1902494 Not Cancer Driver No 17 0.102 44 3 0.068 0
CECR2_ENST00000342247 CECR2 Q9BXF3 Cat eye syndrome critical region protein 2 chr22 GO:1902494 Not Cancer Driver No 222 0.15 1192 183 0.154 0
CFDP1 CFDP1 Q9UEE9 Craniofacial development protein 1 chr16 GO:1902494 Not Cancer Driver No 21 0.07 273 18 0.066 0
CFH CFH P08603 Complement factor H chr1 GO:1902494 Not Cancer Driver No 355 0.288 89 28 0.315 42
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:1902494 Not Cancer Driver No 40 0.083 44 2 0.045 0
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 GO:1902494 Not Cancer Driver No 235 0.117 1015 122 0.12 18
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 GO:1902494 Census, Compendium Yes 419 0.219 974 177 0.182 6
CHD5 CHD5 Q8TDI0 Chromodomain-helicase-DNA-binding protein 5 chr1 GO:1902494 Not Cancer Driver No 365 0.187 931 183 0.197 0
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 GO:1902494 Not Cancer Driver No 328 0.127 1411 148 0.105 0
CHM CHM P24386 Rab proteins geranylgeranyltransferase component A 1 chrX GO:1902494 Not Cancer Driver No 113 0.173 179 40 0.223 3
CHML CHML P26374 Rab proteins geranylgeranyltransferase component A 2 chr1 GO:1902494 Not Cancer Driver No 91 0.139 197 25 0.127 0
CHRAC1 CHRAC1 Q9NRG0 Chromatin accessibility complex protein 1 chr8 GO:1902494 Not Cancer Driver No 10 0.076 35 8 0.229 0
CHUK CHUK O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha chr10 GO:1902494 Not Cancer Driver No 74 0.099 116 9 0.078 0
CLNS1A_ENST00000528364 CLNS1A P54105 Methylosome subunit pICln chr11 GO:1902494 Not Cancer Driver No 19 0.08 170 13 0.076 0
CLP1 CLP1 Q92989 Polyribonucleotide 5'-hydroxyl-kinase Clp1 chr11 GO:1902494 Census Yes 59 0.139 58 12 0.207 1
CNEP1R1_ENST00000427478 CNEP1R1 Q8N9A8 Nuclear envelope phosphatase-regulatory subunit 1 chr16 GO:1902494 Not Cancer Driver No 8 0.064 0 0 0.0 0
CNTD2 CCNP Q9H8S5 Cyclin-P chr19 GO:1902494 Not Cancer Driver No 25 0.081 55 3 0.055 0
COMMD1 COMMD1 Q8N668 COMM domain-containing protein 1 chr2 GO:1902494 Not Cancer Driver No 21 0.111 17 0 0.0 0
COP1 COP1 Q8NHY2 E3 ubiquitin-protein ligase COP1 chr1 GO:1902494 Not Cancer Driver No 106 0.145 147 11 0.075 0
CRBN CRBN Q96SW2 Protein cereblon chr3 GO:1902494 Not Cancer Driver No 52 0.118 76 10 0.132 1
CRCP CRCP O75575 DNA-directed RNA polymerase III subunit RPC9 chr7 GO:1902494 Not Cancer Driver No 11 0.074 113 4 0.035 0
CRNKL1 CRNKL1 Q9BZJ0 Crooked neck-like protein 1 chr20 GO:1902494 Census, Compendium Yes 123 0.145 241 38 0.158 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 GO:1902494 Not Cancer Driver No 71 0.182 75 8 0.107 4
CTDNEP1_ENST00000318988 CTDNEP1 O95476 CTD nuclear envelope phosphatase 1 chr17 GO:1902494 Not Cancer Driver No 20 0.082 0 0 0.0 0
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 GO:1902494 Not Cancer Driver No 151 0.195 65 9 0.138 0
CUL2_ENST00000374748 CUL2 Q13617 Cullin-2 chr10 GO:1902494 Not Cancer Driver No 87 0.117 66 3 0.045 0
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:1902494 Census, Compendium Yes 123 0.16 167 23 0.138 3
CUL4A CUL4A Q13619 Cullin-4A chr13 GO:1902494 Not Cancer Driver No 64 0.084 102 2 0.02 0
CUL4B CUL4B Q13620 Cullin-4B chrX GO:1902494 Not Cancer Driver No 138 0.151 207 38 0.184 2
CUL5 CUL5 Q93034 Cullin-5 chr11 GO:1902494 Not Cancer Driver No 97 0.124 5 1 0.2 0
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 GO:1902494 Not Cancer Driver No 188 0.111 372 41 0.11 3
CWC15 CWC15 Q9P013 Spliceosome-associated protein CWC15 homolog chr11 GO:1902494 Not Cancer Driver No 23 0.1 204 21 0.103 0
CWC22 CWC22 Q9HCG8 Pre-mRNA-splicing factor CWC22 homolog chr2 GO:1902494 Not Cancer Driver No 104 0.115 494 56 0.113 0
CXXC1_ENST00000285106 CXXC1 Q9P0U4 CXXC-type zinc finger protein 1 chr18 GO:1902494 Not Cancer Driver No 115 0.175 366 65 0.178 0
CYB5B CYB5B O43169 Cytochrome b5 type B chr16 GO:1902494 Not Cancer Driver No 17 0.113 58 2 0.034 0
CYB5R3_ENST00000352397 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 GO:1902494 Not Cancer Driver No 42 0.14 24 3 0.125 9
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:1902494 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYBB CYBB P04839 Cytochrome b-245 heavy chain chrX GO:1902494 Not Cancer Driver No 109 0.191 11 3 0.273 65
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 GO:1902494 Not Cancer Driver No 193 0.135 114 11 0.096 0
DBT DBT P11182 Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial chr1 GO:1902494 Not Cancer Driver No 64 0.133 81 11 0.136 3
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:1902494 Not Cancer Driver No 126 0.111 50 8 0.16 4
DDB2 DDB2 Q92466 DNA damage-binding protein 2 chr11 GO:1902494 Census, Compendium Yes 45 0.105 70 5 0.071 2
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:1902494 Not Cancer Driver No 72 0.092 342 30 0.088 0
DECR1 DECR1 Q16698 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial chr8 GO:1902494 Not Cancer Driver No 38 0.113 11 0 0.0 0
DEK DEK P35659 Protein DEK chr6 GO:1902494 Census Yes 47 0.125 297 41 0.138 0
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 GO:1902494 Not Cancer Driver No 28 0.112 11 1 0.091 0
DERL2 DERL2 Q9GZP9 Derlin-2 chr17 GO:1902494 Not Cancer Driver No 19 0.079 15 1 0.067 0
DERL3_ENST00000318109 DERL3 Q96Q80 Derlin-3 chr22 GO:1902494 Not Cancer Driver No 18 0.077 18 1 0.056 0
DET1_ENST00000268148 DET1 Q7L5Y6 DET1 homolog chr15 GO:1902494 Not Cancer Driver No 97 0.176 42 12 0.286 0
DGCR8 DGCR8 Q8WYQ5 Microprocessor complex subunit DGCR8 chr22 GO:1902494 Census, Compendium Yes 102 0.132 466 57 0.122 0
DHDDS_ENST00000236342 DHDDS Q86SQ9 Dehydrodolichyl diphosphate synthase complex subunit DHDDS chr1 GO:1902494 Not Cancer Driver No 38 0.114 19 1 0.053 1
DHX8 DHX8 Q14562 ATP-dependent RNA helicase DHX8 chr17 GO:1902494 Not Cancer Driver No 138 0.113 490 72 0.147 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:1902494 Compendium Yes 182 0.143 331 42 0.127 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:1902494 Census, Compendium Yes 264 0.137 362 45 0.124 4
DIS3 DIS3 Q9Y2L1 Exosome complex exonuclease RRP44 chr13 GO:1902494 Compendium Yes 121 0.126 235 32 0.136 0
DIS3L DIS3L Q8TF46 DIS3-like exonuclease 1 chr15 GO:1902494 Not Cancer Driver No 111 0.105 139 20 0.144 0
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX GO:1902494 Not Cancer Driver No 62 0.121 145 29 0.2 24
DLAT DLAT P10515 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial chr11 GO:1902494 Not Cancer Driver No 63 0.097 294 42 0.143 0
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 GO:1902494 Not Cancer Driver No 67 0.132 17 0 0.0 10
DLST DLST P36957 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial chr14 GO:1902494 Not Cancer Driver No 53 0.117 190 32 0.168 1
DMAP1_ENST00000315913 DMAP1 Q9NPF5 DNA methyltransferase 1-associated protein 1 chr1 GO:1902494 Not Cancer Driver No 49 0.105 269 28 0.104 0
DNMT3A DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 GO:1902494 Census, Compendium Yes 194 0.213 371 59 0.159 16
DNMT3B DNMT3B Q9UBC3 DNA (cytosine-5)-methyltransferase 3B chr20 GO:1902494 Not Cancer Driver No 153 0.179 328 71 0.216 16
DNMT3L_ENST00000628202 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 GO:1902494 Not Cancer Driver No 83 0.215 10 1 0.1 0
DPF1_ENST00000456296 DPF1 Q92782 Zinc finger protein neuro-d4 chr19 GO:1902494 Not Cancer Driver No 32 0.083 85 7 0.082 0
DPF2_ENST00000528416 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 GO:1902494 Not Cancer Driver No 67 0.171 179 30 0.168 5
DPF3_ENST00000556509 DPF3 Q92784 Zinc finger protein DPF3 chr14 GO:1902494 Not Cancer Driver No 68 0.18 172 45 0.262 0
DPM1_ENST00000371588 DPM1 O60762 Dolichol-phosphate mannosyltransferase subunit 1 chr20 GO:1902494 Not Cancer Driver No 38 0.146 29 6 0.207 3
DPM2 DPM2 O94777 Dolichol phosphate-mannose biosynthesis regulatory protein chr9 GO:1902494 Not Cancer Driver No 9 0.107 0 0 0.0 1
DPM3_ENST00000341298 DPM3 Q9P2X0 Dolichol-phosphate mannosyltransferase subunit 3 chr1 GO:1902494 Not Cancer Driver No 8 0.087 0 0 0.0 1
DPY30 DPY30 Q9C005 Protein dpy-30 homolog chr2 GO:1902494 Not Cancer Driver No 10 0.101 57 6 0.105 0
DR1_ENST00000370267 DR1 Q01658 Protein Dr1 chr1 GO:1902494 Not Cancer Driver No 21 0.119 84 12 0.143 0
DROSHA_ENST00000344624 DROSHA Q9NRR4 Ribonuclease 3 chr5 GO:1902494 Census, Compendium Yes 175 0.127 682 100 0.147 0
DTL DTL Q9NZJ0 Denticleless protein homolog chr1 GO:1902494 Not Cancer Driver No 73 0.1 331 49 0.148 0
DUOX1 DUOX1 Q9NRD9 Dual oxidase 1 chr15 GO:1902494 Not Cancer Driver No 193 0.124 158 17 0.108 0
DUOX2 DUOX2 Q9NRD8 Dual oxidase 2 chr15 GO:1902494 Not Cancer Driver No 245 0.158 182 25 0.137 3
DYDC1_ENST00000421924 DYDC1 Q8WWB3 DPY30 domain-containing protein 1 chr10 GO:1902494 Not Cancer Driver No 29 0.164 94 17 0.181 0
DYDC2_ENST00000616870 DYDC2 Q96IM9 DPY30 domain-containing protein 2 chr10 GO:1902494 Not Cancer Driver No 33 0.186 133 27 0.203 0
E2F6 E2F6 O75461 Transcription factor E2F6 chr2 GO:1902494 Not Cancer Driver No 20 0.071 105 10 0.095 0
EEA1 EEA1 Q15075 Early endosome antigen 1 chr12 GO:1902494 Not Cancer Driver No 151 0.107 1168 126 0.108 0
EED_ENST00000263360 EED O75530 Polycomb protein EED chr11 GO:1902494 Census Yes 64 0.145 79 11 0.139 6
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 GO:1902494 Compendium Yes 132 0.136 179 30 0.168 3
EID3 EID3 Q8N140 EP300-interacting inhibitor of differentiation 3 chr12 GO:1902494 Not Cancer Driver No 40 0.12 55 6 0.109 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 GO:1902494 Not Cancer Driver No 50 0.122 57 6 0.105 1
ELOB_ENST00000409906 ELOB Q15370 Elongin-B chr16 GO:1902494 Not Cancer Driver No 13 0.11 69 10 0.145 0
ELOC ELOC Q15369 Elongin-C chr8 GO:1902494 Not Cancer Driver No 22 0.196 25 5 0.2 0
ELOVL6 ELOVL6 Q9H5J4 Elongation of very long chain fatty acids protein 6 chr4 GO:1902494 Not Cancer Driver No 40 0.151 0 0 0.0 0
EME1_ENST00000338165 EME1 Q96AY2 Crossover junction endonuclease EME1 chr17 GO:1902494 Not Cancer Driver No 56 0.098 296 30 0.101 0
EME2 EME2 A4GXA9 Probable crossover junction endonuclease EME2 chr16 GO:1902494 Not Cancer Driver No 28 0.074 125 7 0.056 0
ENC1_ENST00000302351 ENC1 O14682 Ectoderm-neural cortex protein 1 chr5 GO:1902494 Not Cancer Driver No 85 0.144 8 0 0.0 0
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:1902494 Not Cancer Driver No 51 0.118 21 2 0.095 0
ENO2 ENO2 P09104 Gamma-enolase chr12 GO:1902494 Not Cancer Driver No 48 0.111 12 2 0.167 0
ENO3 ENO3 P13929 Beta-enolase chr17 GO:1902494 Not Cancer Driver No 46 0.106 26 1 0.038 2
ENO4 ENO4 A6NNW6 Enolase 4 chr10 GO:1902494 Not Cancer Driver No 13 0.021 197 4 0.02 0
EP400 EP400 Q96L91 E1A-binding protein p400 chr12 GO:1902494 Not Cancer Driver No 397 0.126 2064 234 0.113 0
EPC1 EPC1 Q9H2F5 Enhancer of polycomb homolog 1 chr10 GO:1902494 Not Cancer Driver No 104 0.124 515 68 0.132 0
EPC2 EPC2 Q52LR7 Enhancer of polycomb homolog 2 chr2 GO:1902494 Not Cancer Driver No 95 0.118 583 67 0.115 0
ERC1 ERC1 Q8IUD2 ELKS/Rab6-interacting/CAST family member 1 chr12 GO:1902494 Census Yes 127 0.114 1013 119 0.117 0
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:1902494 Not Cancer Driver No 211 0.141 829 117 0.141 9
ERCC8 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 GO:1902494 Not Cancer Driver No 25 0.063 53 8 0.151 7
ERH ERH P84090 Enhancer of rudimentary homolog chr14 GO:1902494 Not Cancer Driver No 7 0.067 11 0 0.0 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:1902494 Not Cancer Driver No 125 0.128 250 28 0.112 0
ETFA ETFA P13804 Electron transfer flavoprotein subunit alpha, mitochondrial chr15 GO:1902494 Not Cancer Driver No 30 0.09 34 2 0.059 3
ETFB_ENST00000309244 ETFB P38117 Electron transfer flavoprotein subunit beta chr19 GO:1902494 Not Cancer Driver No 37 0.145 38 4 0.105 2
EXOSC1 EXOSC1 Q9Y3B2 Exosome complex component CSL4 chr10 GO:1902494 Not Cancer Driver No 14 0.072 14 2 0.143 1
EXOSC10 EXOSC10 Q01780 Exosome component 10 chr1 GO:1902494 Not Cancer Driver No 87 0.098 375 35 0.093 0
EXOSC2 EXOSC2 Q13868 Exosome complex component RRP4 chr9 GO:1902494 Not Cancer Driver No 21 0.072 47 6 0.128 2
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:1902494 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC4 EXOSC4 Q9NPD3 Exosome complex component RRP41 chr8 GO:1902494 Not Cancer Driver No 34 0.139 23 0 0.0 0
EXOSC5 EXOSC5 Q9NQT4 Exosome complex component RRP46 chr19 GO:1902494 Not Cancer Driver No 43 0.183 31 3 0.097 0
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:1902494 Not Cancer Driver No 3 0.011 102 0 0.0 0
EXOSC7 EXOSC7 Q15024 Exosome complex component RRP42 chr3 GO:1902494 Not Cancer Driver No 41 0.141 8 1 0.125 0
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 GO:1902494 Not Cancer Driver No 20 0.072 28 1 0.036 2
EXOSC9_ENST00000243498 EXOSC9 Q06265 Exosome complex component RRP45 chr4 GO:1902494 Not Cancer Driver No 58 0.132 154 18 0.117 1
EZH1 EZH1 Q92800 Histone-lysine N-methyltransferase EZH1 chr17 GO:1902494 Not Cancer Driver No 82 0.11 213 21 0.099 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:1902494 Census, Compendium Yes 120 0.161 284 44 0.155 11
F3 F3 P13726 Tissue factor chr1 GO:1902494 Not Cancer Driver No 28 0.095 61 7 0.115 0
F7 F7 P08709 Coagulation factor VII chr13 GO:1902494 Not Cancer Driver No 74 0.159 50 7 0.14 108
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:1902494 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM8A1 FAM8A1 Q9UBU6 Protein FAM8A1 chr6 GO:1902494 Not Cancer Driver No 34 0.082 196 14 0.071 0
FARSA FARSA Q9Y285 Phenylalanine--tRNA ligase alpha subunit chr19 GO:1902494 Not Cancer Driver No 75 0.148 120 25 0.208 0
FARSB FARSB Q9NSD9 Phenylalanine--tRNA ligase beta subunit chr2 GO:1902494 Not Cancer Driver No 71 0.121 0 0 0.0 8
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:1902494 Census, Compendium Yes 322 0.455 230 38 0.165 0
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:1902494 Not Cancer Driver No 68 0.114 120 4 0.033 0
FCN1 FCN1 O00602 Ficolin-1 chr9 GO:1902494 Not Cancer Driver No 107 0.328 88 15 0.17 0
FCN2 FCN2 Q15485 Ficolin-2 chr9 GO:1902494 Not Cancer Driver No 73 0.233 80 19 0.237 0
FCN3 FCN3 O75636 Ficolin-3 chr1 GO:1902494 Not Cancer Driver No 46 0.154 65 19 0.292 0
FEM1A FEM1A Q9BSK4 Protein fem-1 homolog A chr19 GO:1902494 Not Cancer Driver No 68 0.102 162 22 0.136 0
FEM1B FEM1B Q9UK73 Protein fem-1 homolog B chr15 GO:1902494 Not Cancer Driver No 69 0.11 33 3 0.091 0
FEM1C FEM1C Q96JP0 Protein fem-1 homolog C chr5 GO:1902494 Not Cancer Driver No 55 0.089 27 1 0.037 0
FNTA FNTA P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha chr8 GO:1902494 Not Cancer Driver No 43 0.113 92 12 0.13 0
FNTB FNTB P49356 Protein farnesyltransferase subunit beta chr14 GO:1902494 Not Cancer Driver No 36 0.082 31 1 0.032 0
GAN GAN Q9H2C0 Gigaxonin chr16 GO:1902494 Not Cancer Driver No 74 0.124 33 6 0.182 19
GAR1 GAR1 Q9NY12 H/ACA ribonucleoprotein complex subunit 1 chr4 GO:1902494 Not Cancer Driver No 23 0.106 141 14 0.099 0
GATAD2A_ENST00000360315 GATAD2A Q86YP4 Transcriptional repressor p66-alpha chr19 GO:1902494 Not Cancer Driver No 88 0.139 548 77 0.141 0
GATAD2B_ENST00000634544 GATAD2B Q8WXI9 Transcriptional repressor p66-beta chr1 GO:1902494 Not Cancer Driver No 76 0.128 510 67 0.131 0
GBA3 GBA3 Q9H227 Cytosolic beta-glucosidase chr4 GO:1902494 Not Cancer Driver No 118 0.252 18 6 0.333 0
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:1902494 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:1902494 Not Cancer Driver No 32 0.117 31 3 0.097 0
GCSH GCSH P23434 Glycine cleavage system H protein, mitochondrial chr16 GO:1902494 Not Cancer Driver No 15 0.087 25 0 0.0 0
GLDC GLDC P23378 Glycine dehydrogenase (decarboxylating), mitochondrial chr9 GO:1902494 Not Cancer Driver No 152 0.149 112 7 0.062 22
GLMN GLMN Q92990 Glomulin chr1 GO:1902494 Not Cancer Driver No 49 0.082 37 6 0.162 0
GMPR GMPR P36959 GMP reductase 1 chr6 GO:1902494 Not Cancer Driver No 52 0.151 17 3 0.176 0
GMPR2_ENST00000399440 GMPR2 Q9P2T1 GMP reductase 2 chr14 GO:1902494 Not Cancer Driver No 30 0.086 9 1 0.111 0
GNA11 GNA11 P29992 Guanine nucleotide-binding protein subunit alpha-11 chr19 GO:1902494 Census, Compendium Yes 48 0.134 10 0 0.0 5
GNA12 GNA12 Q03113 Guanine nucleotide-binding protein subunit alpha-12 chr7 GO:1902494 Not Cancer Driver No 41 0.108 20 0 0.0 0
GNA13 GNA13 Q14344 Guanine nucleotide-binding protein subunit alpha-13 chr17 GO:1902494 Compendium Yes 52 0.138 32 4 0.125 0
GNA14 GNA14 O95837 Guanine nucleotide-binding protein subunit alpha-14 chr9 GO:1902494 Not Cancer Driver No 62 0.175 11 2 0.182 0
GNA15 GNA15 P30679 Guanine nucleotide-binding protein subunit alpha-15 chr19 GO:1902494 Not Cancer Driver No 51 0.136 15 6 0.4 0
GNAI1 GNAI1 P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 chr7 GO:1902494 Not Cancer Driver No 52 0.147 11 3 0.273 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 GO:1902494 Compendium Yes 50 0.141 24 0 0.0 0
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 GO:1902494 Not Cancer Driver No 42 0.119 11 0 0.0 1
GNAL_ENST00000269162 GNAL P38405 Guanine nucleotide-binding protein G(olf) subunit alpha chr18 GO:1902494 Not Cancer Driver No 56 0.147 46 4 0.087 2
GNAO1_ENST00000638705 GNAO1 P09471 Guanine nucleotide-binding protein G(o) subunit alpha chr16 GO:1902494 Not Cancer Driver No 54 0.153 10 0 0.0 15
GNAQ GNAQ P50148 Guanine nucleotide-binding protein G(q) subunit alpha chr9 GO:1902494 Census, Compendium Yes 57 0.159 14 1 0.071 1
GNAT1 GNAT1 P11488 Guanine nucleotide-binding protein G(t) subunit alpha-1 chr3 GO:1902494 Not Cancer Driver No 43 0.123 39 6 0.154 3
GNAT2 GNAT2 P19087 Guanine nucleotide-binding protein G(t) subunit alpha-2 chr1 GO:1902494 Not Cancer Driver No 38 0.107 44 7 0.159 0
GNAT3 GNAT3 A8MTJ3 Guanine nucleotide-binding protein G(t) subunit alpha-3 chr7 GO:1902494 Not Cancer Driver No 61 0.172 38 6 0.158 0
GNAZ GNAZ P19086 Guanine nucleotide-binding protein G(z) subunit alpha chr22 GO:1902494 Not Cancer Driver No 84 0.237 30 13 0.433 0
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 GO:1902494 Not Cancer Driver No 45 0.132 24 2 0.083 16
GNB2 GNB2 P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 chr7 GO:1902494 Not Cancer Driver No 50 0.147 21 0 0.0 7
GNB3 GNB3 P16520 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 chr12 GO:1902494 Not Cancer Driver No 51 0.15 13 1 0.077 0
GNB4_ENST00000468623 GNB4 Q9HAV0 Guanine nucleotide-binding protein subunit beta-4 chr3 GO:1902494 Not Cancer Driver No 49 0.144 27 3 0.111 2
GNB5 GNB5 O14775 Guanine nucleotide-binding protein subunit beta-5 chr15 GO:1902494 Not Cancer Driver No 60 0.152 16 1 0.062 1
GNG10 GNG10 P50151 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 chr9 GO:1902494 Not Cancer Driver No 5 0.074 0 0 0.0 0
GNG11 GNG11 P61952 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 chr7 GO:1902494 Not Cancer Driver No 14 0.192 66 13 0.197 0
GNG12 GNG12 Q9UBI6 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 chr1 GO:1902494 Not Cancer Driver No 10 0.139 26 5 0.192 0
GNG13 GNG13 Q9P2W3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 chr16 GO:1902494 Not Cancer Driver No 17 0.254 12 2 0.167 0
GNG2_ENST00000615906 GNG2 P59768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 chr14 GO:1902494 Not Cancer Driver No 17 0.239 12 3 0.25 0
GNG3 GNG3 P63215 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 chr11 GO:1902494 Not Cancer Driver No 10 0.133 20 1 0.05 0
GNG4 GNG4 P50150 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 chr1 GO:1902494 Not Cancer Driver No 21 0.28 22 2 0.091 0
GNG5_ENST00000370645 GNG5 P63218 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 chr1 GO:1902494 Not Cancer Driver No 5 0.074 9 1 0.111 0
GNG7 GNG7 O60262 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 chr19 GO:1902494 Not Cancer Driver No 13 0.191 10 1 0.1 0
GNG8 GNG8 Q9UK08 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 chr19 GO:1902494 Not Cancer Driver No 2 0.029 16 1 0.062 0
GNGT1_ENST00000429473 GNGT1 P63211 Guanine nucleotide-binding protein G(T) subunit gamma-T1 chr7 GO:1902494 Not Cancer Driver No 14 0.189 25 4 0.16 0
GNGT2_ENST00000511673 GNGT2 O14610 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 chr17 GO:1902494 Not Cancer Driver No 15 0.217 65 14 0.215 0
GOLGA7B GOLGA7B Q2TAP0 Golgin subfamily A member 7B chr10 GO:1902494 Not Cancer Driver No 22 0.132 24 0 0.0 0
GOLGA7_ENST00000518270 GOLGA7 Q7Z5G4 Golgin subfamily A member 7 chr8 GO:1902494 Not Cancer Driver No 8 0.058 6 0 0.0 0
GPAA1 GPAA1 O43292 Glycosylphosphatidylinositol anchor attachment 1 protein chr8 GO:1902494 Not Cancer Driver No 55 0.089 20 3 0.15 5
GPD1 GPD1 P21695 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic chr12 GO:1902494 Not Cancer Driver No 59 0.169 2 0 0.0 1
GPD1L GPD1L Q8N335 Glycerol-3-phosphate dehydrogenase 1-like protein chr3 GO:1902494 Not Cancer Driver No 40 0.114 13 1 0.077 0
GPD2_ENST00000438166 GPD2 P43304 Glycerol-3-phosphate dehydrogenase, mitochondrial chr2 GO:1902494 Not Cancer Driver No 88 0.121 67 7 0.104 0
GPIHBP1 GPIHBP1 Q8IV16 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 chr8 GO:1902494 Not Cancer Driver No 26 0.141 82 15 0.183 10
GRHPR GRHPR Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase chr9 GO:1902494 Not Cancer Driver No 31 0.095 36 4 0.111 0
GTPBP1 GTPBP1 O00178 GTP-binding protein 1 chr22 GO:1902494 Not Cancer Driver No 75 0.112 263 26 0.099 0
HCFC1 HCFC1 P51610 Host cell factor 1 chrX GO:1902494 Not Cancer Driver No 280 0.138 1345 181 0.135 1
HCFC2 HCFC2 Q9Y5Z7 Host cell factor 2 chr12 GO:1902494 Not Cancer Driver No 95 0.12 279 34 0.122 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:1902494 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:1902494 Not Cancer Driver No 46 0.094 145 14 0.097 0
HEXA_ENST00000268097 HEXA P06865 Beta-hexosaminidase subunit alpha chr15 GO:1902494 Not Cancer Driver No 59 0.112 5 1 0.2 49
HEXB HEXB P07686 Beta-hexosaminidase subunit beta chr5 GO:1902494 Not Cancer Driver No 45 0.081 0 0 0.0 9
HMGXB4 HMGXB4 Q9UGU5 HMG domain-containing protein 4 chr22 GO:1902494 Not Cancer Driver No 68 0.113 475 56 0.118 0
HRAS HRAS P01112 GTPase HRas chr11 GO:1902494 Census, Compendium Yes 107 0.566 16 4 0.25 18
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX GO:1902494 Not Cancer Driver No 27 0.103 15 3 0.2 11
HSD17B12 HSD17B12 Q53GQ0 Very-long-chain 3-oxoacyl-CoA reductase chr11 GO:1902494 Not Cancer Driver No 32 0.103 9 0 0.0 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:1902494 Compendium Yes 44 0.096 127 9 0.071 2
IDH3A IDH3A P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial chr15 GO:1902494 Not Cancer Driver No 41 0.112 47 11 0.234 0
IDH3B_ENST00000380843 IDH3B O43837 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial chr20 GO:1902494 Not Cancer Driver No 32 0.083 49 3 0.061 1
IDH3G IDH3G P51553 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial chrX GO:1902494 Not Cancer Driver No 48 0.122 77 9 0.117 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:1902494 Not Cancer Driver No 183 0.134 265 37 0.14 6
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 GO:1902494 Census, Compendium Yes 106 0.14 211 31 0.147 1
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX GO:1902494 Not Cancer Driver No 6 0.014 301 6 0.02 22
ILVBL ILVBL A1L0T0 2-hydroxyacyl-CoA lyase 2 chr19 GO:1902494 Not Cancer Driver No 86 0.136 30 1 0.033 0
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 GO:1902494 Not Cancer Driver No 33 0.118 169 26 0.154 0
ING3 ING3 Q9NXR8 Inhibitor of growth protein 3 chr7 GO:1902494 Not Cancer Driver No 44 0.105 292 32 0.11 1
ING4 ING4 Q9UNL4 Inhibitor of growth protein 4 chr12 GO:1902494 Not Cancer Driver No 31 0.124 108 15 0.139 0
ING5_ENST00000313552 ING5 Q8WYH8 Inhibitor of growth protein 5 chr2 GO:1902494 Not Cancer Driver No 25 0.104 119 9 0.076 0
INO80C_ENST00000334598 INO80C Q6PI98 INO80 complex subunit C chr18 GO:1902494 Not Cancer Driver No 18 0.094 109 11 0.101 0
INSR INSR P06213 Insulin receptor chr19 GO:1902494 Not Cancer Driver No 190 0.137 280 57 0.204 64
INSRR INSRR P14616 Insulin receptor-related protein chr1 GO:1902494 Not Cancer Driver No 262 0.202 228 37 0.162 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:1902494 Not Cancer Driver No 161 0.13 1072 133 0.124 2
ISY1_ENST00000393295 ISY1 Q9ULR0 Pre-mRNA-splicing factor ISY1 homolog chr3 GO:1902494 Not Cancer Driver No 29 0.102 171 18 0.105 0
ITPR1_ENST00000354582 ITPR1 Q14643 Inositol 1,4,5-trisphosphate receptor type 1 chr3 GO:1902494 Not Cancer Driver No 390 0.141 581 76 0.131 6
JARID2 JARID2 Q92833 Protein Jumonji chr6 GO:1902494 Not Cancer Driver No 190 0.152 724 113 0.156 0
KANSL1L KANSL1L A0AUZ9 KAT8 regulatory NSL complex subunit 1-like protein chr2 GO:1902494 Not Cancer Driver No 127 0.129 410 51 0.124 0
KANSL1_ENST00000262419 KANSL1 Q7Z3B3 KAT8 regulatory NSL complex subunit 1 chr17 GO:1902494 Not Cancer Driver No 168 0.152 876 130 0.148 0
KANSL2 KANSL2 Q9H9L4 KAT8 regulatory NSL complex subunit 2 chr12 GO:1902494 Not Cancer Driver No 53 0.108 304 27 0.089 0
KANSL3 KANSL3 Q9P2N6 KAT8 regulatory NSL complex subunit 3 chr2 GO:1902494 Not Cancer Driver No 92 0.102 547 62 0.113 0
KAT14 KAT14 Q9H8E8 Cysteine-rich protein 2-binding protein chr20 GO:1902494 Not Cancer Driver No 123 0.157 343 57 0.166 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:1902494 Not Cancer Driver No 88 0.105 251 17 0.068 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 GO:1902494 Not Cancer Driver No 107 0.129 266 27 0.102 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 GO:1902494 Not Cancer Driver No 65 0.127 173 21 0.121 3
KAT6A_ENST00000406337 KAT6A Q92794 Histone acetyltransferase KAT6A chr8 GO:1902494 Census, Compendium Yes 273 0.136 1420 193 0.136 0
KAT6B KAT6B Q8WYB5 Histone acetyltransferase KAT6B chr10 GO:1902494 Census, Compendium Yes 238 0.115 1555 197 0.127 0
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 GO:1902494 Census Yes 97 0.159 327 47 0.144 0
KAT8_ENST00000219797 KAT8 Q9H7Z6 Histone acetyltransferase KAT8 chr16 GO:1902494 Not Cancer Driver No 66 0.144 156 20 0.128 4
KBTBD6 KBTBD6 Q86V97 Kelch repeat and BTB domain-containing protein 6 chr13 GO:1902494 Not Cancer Driver No 96 0.142 80 12 0.15 0
KBTBD7 KBTBD7 Q8WVZ9 Kelch repeat and BTB domain-containing protein 7 chr13 GO:1902494 Not Cancer Driver No 92 0.135 105 6 0.057 0
KBTBD8 KBTBD8 Q8NFY9 Kelch repeat and BTB domain-containing protein 8 chr3 GO:1902494 Not Cancer Driver No 96 0.16 31 3 0.097 0
KCTD10 KCTD10 Q9H3F6 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 chr12 GO:1902494 Not Cancer Driver No 68 0.217 73 19 0.26 0
KCTD13 KCTD13 Q8WZ19 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 chr16 GO:1902494 Not Cancer Driver No 33 0.1 95 10 0.105 0
KCTD17 KCTD17 Q8N5Z5 BTB/POZ domain-containing protein KCTD17 chr22 GO:1902494 Not Cancer Driver No 23 0.072 187 14 0.075 1
KCTD2 KCTD2 Q14681 BTB/POZ domain-containing protein KCTD2 chr17 GO:1902494 Not Cancer Driver No 34 0.129 128 11 0.086 0
KCTD5 KCTD5 Q9NXV2 BTB/POZ domain-containing protein KCTD5 chr16 GO:1902494 Not Cancer Driver No 22 0.094 32 3 0.094 0
KDM6A KDM6A O15550 Lysine-specific demethylase 6A chrX GO:1902494 Census, Compendium Yes 173 0.123 648 71 0.11 0
KDM6B_ENST00000448097 KDM6B O15054 Lysine-specific demethylase 6B chr17 GO:1902494 Not Cancer Driver No 189 0.115 1278 142 0.111 2
KEAP1_ENST00000393623 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 GO:1902494 Census, Compendium Yes 237 0.38 57 12 0.211 0
KIAA0391 PRORP O15091 Mitochondrial ribonuclease P catalytic subunit chr14 GO:1902494 Not Cancer Driver No 62 0.106 60 12 0.2 0
KLHDC1 KLHDC1 Q8N7A1 Kelch domain-containing protein 1 chr14 GO:1902494 Not Cancer Driver No 36 0.089 37 7 0.189 0
KLHDC10 KLHDC10 Q6PID8 Kelch domain-containing protein 10 chr7 GO:1902494 Not Cancer Driver No 40 0.09 93 3 0.032 0
KLHDC2 KLHDC2 Q9Y2U9 Kelch domain-containing protein 2 chr14 GO:1902494 Not Cancer Driver No 39 0.096 42 2 0.048 0
KLHDC3 KLHDC3 Q9BQ90 Kelch domain-containing protein 3 chr6 GO:1902494 Not Cancer Driver No 43 0.113 12 1 0.083 0
KLHL12 KLHL12 Q53G59 Kelch-like protein 12 chr1 GO:1902494 Not Cancer Driver No 65 0.114 33 6 0.182 0
KLHL13_ENST00000262820 KLHL13 Q9P2N7 Kelch-like protein 13 chrX GO:1902494 Not Cancer Driver No 159 0.243 51 17 0.333 0
KLHL20 KLHL20 Q9Y2M5 Kelch-like protein 20 chr1 GO:1902494 Not Cancer Driver No 83 0.136 143 17 0.119 0
KLHL21 KLHL21 Q9UJP4 Kelch-like protein 21 chr1 GO:1902494 Not Cancer Driver No 43 0.072 63 7 0.111 0
KLHL22 KLHL22 Q53GT1 Kelch-like protein 22 chr22 GO:1902494 Not Cancer Driver No 90 0.142 50 8 0.16 0
KLHL24_ENST00000242810 KLHL24 Q6TFL4 Kelch-like protein 24 chr3 GO:1902494 Not Cancer Driver No 102 0.17 17 6 0.353 0
KLHL25 KLHL25 Q9H0H3 Kelch-like protein 25 chr15 GO:1902494 Not Cancer Driver No 83 0.141 32 7 0.219 0
KLHL2_ENST00000226725 KLHL2 O95198 Kelch-like protein 2 chr4 GO:1902494 Not Cancer Driver No 80 0.135 42 5 0.119 0
KLHL3 KLHL3 Q9UH77 Kelch-like protein 3 chr5 GO:1902494 Not Cancer Driver No 67 0.114 34 9 0.265 32
KLHL40 KLHL40 Q2TBA0 Kelch-like protein 40 chr3 GO:1902494 Not Cancer Driver No 108 0.174 44 8 0.182 13
KLHL41 KLHL41 O60662 Kelch-like protein 41 chr2 GO:1902494 Not Cancer Driver No 69 0.114 18 2 0.111 1
KLHL42 KLHL42 Q9P2K6 Kelch-like protein 42 chr12 GO:1902494 Not Cancer Driver No 48 0.095 57 4 0.07 0
KLHL7 KLHL7 Q8IXQ5 Kelch-like protein 7 chr7 GO:1902494 Not Cancer Driver No 85 0.145 31 4 0.129 6
KLHL8 KLHL8 Q9P2G9 Kelch-like protein 8 chr4 GO:1902494 Not Cancer Driver No 75 0.121 63 7 0.111 0
KLHL9 KLHL9 Q9P2J3 Kelch-like protein 9 chr9 GO:1902494 Not Cancer Driver No 70 0.113 26 4 0.154 0
KMT2A_ENST00000389506 KMT2A Q03164 Histone-lysine N-methyltransferase 2A chr11 GO:1902494 Census, Compendium Yes 446 0.112 3145 338 0.107 0
KMT2B KMT2B Q9UMN6 Histone-lysine N-methyltransferase 2B chr19 GO:1902494 Compendium Yes 378 0.139 1895 227 0.12 0
KMT2C_ENST00000355193 KMT2C Q8NEZ4 Histone-lysine N-methyltransferase 2C chr7 GO:1902494 Census, Compendium Yes 835 0.17 3599 517 0.144 0
KMT2D KMT2D O14686 Histone-lysine N-methyltransferase 2D chr12 GO:1902494 Census, Compendium Yes 773 0.14 4386 552 0.126 13
LAS1L LAS1L Q9Y4W2 Ribosomal biogenesis protein LAS1L chrX GO:1902494 Not Cancer Driver No 100 0.136 279 49 0.176 0
LPL LPL P06858 Lipoprotein lipase chr8 GO:1902494 Not Cancer Driver No 94 0.198 23 3 0.13 70
LZTR1_ENST00000646124 LZTR1 Q8N653 Leucine-zipper-like transcriptional regulator 1 chr22 GO:1902494 Census, Compendium Yes 160 0.19 106 18 0.17 26
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:1902494 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAGOHB MAGOHB Q96A72 Protein mago nashi homolog 2 chr12 GO:1902494 Not Cancer Driver No 15 0.101 6 1 0.167 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:1902494 Not Cancer Driver No 104 0.172 333 66 0.198 6
MARC1 MTARC1 Q5VT66 Mitochondrial amidoxime-reducing component 1 chr1 GO:1902494 Not Cancer Driver No 49 0.145 26 6 0.231 0
MARCH6 MARCHF6 O60337 E3 ubiquitin-protein ligase MARCHF6 chr5 GO:1902494 Not Cancer Driver No 114 0.125 114 13 0.114 0
MAT1A MAT1A Q00266 S-adenosylmethionine synthase isoform type-1 chr10 GO:1902494 Not Cancer Driver No 74 0.187 15 0 0.0 12
MAT2A MAT2A P31153 S-adenosylmethionine synthase isoform type-2 chr2 GO:1902494 Not Cancer Driver No 36 0.091 31 4 0.129 0
MAT2B MAT2B Q9NZL9 Methionine adenosyltransferase 2 subunit beta chr5 GO:1902494 Not Cancer Driver No 42 0.126 59 8 0.136 0
MAX MAX P61244 Protein max chr14 GO:1902494 Census, Compendium Yes 45 0.281 160 45 0.281 9
MBD3 MBD3 O95983 Methyl-CpG-binding domain protein 3 chr19 GO:1902494 Not Cancer Driver No 50 0.172 246 46 0.187 0
MBIP MBIP Q9NS73 MAP3K12-binding inhibitory protein 1 chr14 GO:1902494 Not Cancer Driver No 47 0.137 190 20 0.105 0
MBL2 MBL2 P11226 Mannose-binding protein C chr10 GO:1902494 Not Cancer Driver No 63 0.254 122 32 0.262 0
MCCC1 MCCC1 Q96RQ3 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial chr3 GO:1902494 Not Cancer Driver No 94 0.13 162 17 0.105 33
MCCC2 MCCC2 Q9HCC0 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial chr5 GO:1902494 Not Cancer Driver No 60 0.107 25 2 0.08 52
MCM3_ENST00000229854 MCM3 P25205 DNA replication licensing factor MCM3 chr6 GO:1902494 Not Cancer Driver No 92 0.114 310 47 0.152 0
MCRS1_ENST00000550165 MCRS1 Q96EZ8 Microspherule protein 1 chr12 GO:1902494 Not Cancer Driver No 72 0.156 151 18 0.119 0
MEAF6_ENST00000296214 MEAF6 Q9HAF1 Chromatin modification-related protein MEAF6 chr1 GO:1902494 Not Cancer Driver No 22 0.115 171 21 0.123 0
MEN1 MEN1 O00255 Menin chr11 GO:1902494 Census, Compendium Yes 73 0.119 228 15 0.066 90
METTL1 METTL1 Q9UBP6 tRNA (guanine-N(7)-)-methyltransferase chr12 GO:1902494 Not Cancer Driver No 43 0.156 89 11 0.124 0
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 GO:1902494 Not Cancer Driver No 60 0.132 224 26 0.116 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:1902494 Not Cancer Driver No 74 0.128 274 29 0.106 0
MGA MGA Q8IWI9 MAX gene-associated protein chr15 GO:1902494 Compendium Yes 341 0.111 2317 259 0.112 0
MNAT1 MNAT1 P51948 CDK-activating kinase assembly factor MAT1 chr14 GO:1902494 Not Cancer Driver No 23 0.074 64 2 0.031 0
MORF4L1 MORF4L1 Q9UBU8 Mortality factor 4-like protein 1 chr15 GO:1902494 Not Cancer Driver No 43 0.119 163 17 0.104 0
MRPS36 MRPS36 P82909 Alpha-ketoglutarate dehydrogenase component 4 chr5 GO:1902494 Not Cancer Driver No 12 0.117 103 12 0.117 0
MSL1_ENST00000398532 MSL1 Q68DK7 Male-specific lethal 1 homolog chr17 GO:1902494 Not Cancer Driver No 32 0.052 525 25 0.048 0
MSL2 MSL2 Q9HCI7 E3 ubiquitin-protein ligase MSL2 chr3 GO:1902494 Not Cancer Driver No 76 0.132 186 34 0.183 0
MSL3 MSL3 Q8N5Y2 Male-specific lethal 3 homolog chrX GO:1902494 Not Cancer Driver No 87 0.167 273 42 0.154 0
MTA1 MTA1 Q13330 Metastasis-associated protein MTA1 chr14 GO:1902494 Not Cancer Driver No 92 0.129 327 42 0.128 0
MTA2 MTA2 O94776 Metastasis-associated protein MTA2 chr11 GO:1902494 Not Cancer Driver No 78 0.117 283 32 0.113 0
MTA3 MTA3 Q9BTC8 Metastasis-associated protein MTA3 chr2 GO:1902494 Not Cancer Driver No 48 0.081 169 18 0.107 0
MUS81 MUS81 Q96NY9 Crossover junction endonuclease MUS81 chr11 GO:1902494 Not Cancer Driver No 67 0.122 232 38 0.164 0
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:1902494 Not Cancer Driver No 144 0.108 463 47 0.102 0
N6AMT1 N6AMT1 Q9Y5N5 Methyltransferase N6AMT1 chr21 GO:1902494 Not Cancer Driver No 44 0.206 20 3 0.15 0
NAA10 NAA10 P41227 N-alpha-acetyltransferase 10 chrX GO:1902494 Not Cancer Driver No 33 0.14 117 17 0.145 3
NAA11 NAA11 Q9BSU3 N-alpha-acetyltransferase 11 chr4 GO:1902494 Not Cancer Driver No 64 0.279 123 31 0.252 0
NAA15 NAA15 Q9BXJ9 N-alpha-acetyltransferase 15, NatA auxiliary subunit chr4 GO:1902494 Not Cancer Driver No 95 0.11 115 17 0.148 0
NAA16 NAA16 Q6N069 N-alpha-acetyltransferase 16, NatA auxiliary subunit chr13 GO:1902494 Not Cancer Driver No 91 0.105 74 12 0.162 0
NAA20 NAA20 P61599 N-alpha-acetyltransferase 20 chr20 GO:1902494 Not Cancer Driver No 26 0.146 28 6 0.214 0
NAA25 NAA25 Q14CX7 N-alpha-acetyltransferase 25, NatB auxiliary subunit chr12 GO:1902494 Not Cancer Driver No 113 0.116 75 5 0.067 0
NAA30 NAA30 Q147X3 N-alpha-acetyltransferase 30 chr14 GO:1902494 Not Cancer Driver No 42 0.116 211 13 0.062 0
NAA35 NAA35 Q5VZE5 N-alpha-acetyltransferase 35, NatC auxiliary subunit chr9 GO:1902494 Not Cancer Driver No 87 0.12 120 22 0.183 0
NAA38_ENST00000575771 NAA38 Q9BRA0 N-alpha-acetyltransferase 38, NatC auxiliary subunit chr17 GO:1902494 Not Cancer Driver No 11 0.088 79 4 0.051 0
NAA50 NAA50 Q9GZZ1 N-alpha-acetyltransferase 50 chr3 GO:1902494 Not Cancer Driver No 14 0.083 14 1 0.071 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:1902494 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCF2 NCF2 P19878 Neutrophil cytosol factor 2 chr1 GO:1902494 Not Cancer Driver No 97 0.184 183 34 0.186 14
NCF4_ENST00000248899 NCF4 Q15080 Neutrophil cytosol factor 4 chr22 GO:1902494 Not Cancer Driver No 60 0.177 27 4 0.148 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:1902494 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCOA6 NCOA6 Q14686 Nuclear receptor coactivator 6 chr20 GO:1902494 Not Cancer Driver No 242 0.117 1941 219 0.113 0
NEU2 NEU2 Q9Y3R4 Sialidase-2 chr2 GO:1902494 Not Cancer Driver No 88 0.232 144 32 0.222 0
NHP2 NHP2 Q9NX24 H/ACA ribonucleoprotein complex subunit 2 chr5 GO:1902494 Not Cancer Driver No 26 0.17 20 4 0.2 2
NKD1 NKD1 Q969G9 Protein naked cuticle homolog 1 chr16 GO:1902494 Not Cancer Driver No 72 0.153 436 67 0.154 0
NOLC1_ENST00000605788 NOLC1 Q14978 Nucleolar and coiled-body phosphoprotein 1 chr10 GO:1902494 Not Cancer Driver No 74 0.106 662 69 0.104 0
NOP10 NOP10 Q9NPE3 H/ACA ribonucleoprotein complex subunit 3 chr15 GO:1902494 Not Cancer Driver No 12 0.188 20 2 0.1 1
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:1902494 Not Cancer Driver No 101 0.179 18 8 0.444 0
NOX3 NOX3 Q9HBY0 NADPH oxidase 3 chr6 GO:1902494 Not Cancer Driver No 118 0.208 3 0 0.0 0
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:1902494 Not Cancer Driver No 123 0.213 0 0 0.0 0
NOXA1 NOXA1 Q86UR1 NADPH oxidase activator 1 chr9 GO:1902494 Not Cancer Driver No 27 0.057 215 14 0.065 0
NOXO1 NOXO1 Q8NFA2 NADPH oxidase organizer 1 chr16 GO:1902494 Not Cancer Driver No 29 0.077 182 9 0.049 0
NSMCE1 NSMCE1 Q8WV22 Non-structural maintenance of chromosomes element 1 homolog chr16 GO:1902494 Not Cancer Driver No 40 0.15 31 8 0.258 0
NSMCE2_ENST00000522563 NSMCE2 Q96MF7 E3 SUMO-protein ligase NSE2 chr8 GO:1902494 Not Cancer Driver No 30 0.121 119 12 0.101 0
NSMCE3 NSMCE3 Q96MG7 Non-structural maintenance of chromosomes element 3 homolog chr15 GO:1902494 Not Cancer Driver No 33 0.109 128 7 0.055 2
NSMCE4A NSMCE4A Q9NXX6 Non-structural maintenance of chromosomes element 4 homolog A chr10 GO:1902494 Not Cancer Driver No 17 0.044 200 5 0.025 0
NUS1 NUS1 Q96E22 Dehydrodolichyl diphosphate synthase complex subunit NUS1 chr6 GO:1902494 Not Cancer Driver No 21 0.072 13 0 0.0 1
OGDH OGDH Q02218 2-oxoglutarate dehydrogenase complex component E1 chr7 GO:1902494 Not Cancer Driver No 150 0.147 106 19 0.179 0
OGDHL OGDHL Q9ULD0 2-oxoglutarate dehydrogenase-like, mitochondrial chr10 GO:1902494 Not Cancer Driver No 262 0.259 128 38 0.297 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX GO:1902494 Not Cancer Driver No 156 0.149 89 16 0.18 2
ORMDL1_ENST00000392350 ORMDL1 Q9P0S3 ORM1-like protein 1 chr2 GO:1902494 Not Cancer Driver No 12 0.078 0 0 0.0 0
ORMDL2_ENST00000548974 ORMDL2 Q53FV1 ORM1-like protein 2 chr12 GO:1902494 Not Cancer Driver No 10 0.065 0 0 0.0 0
ORMDL3_ENST00000304046 ORMDL3 Q8N138 ORM1-like protein 3 chr17 GO:1902494 Not Cancer Driver No 22 0.144 9 1 0.111 0
OS9 OS9 Q13438 Protein OS-9 chr12 GO:1902494 Not Cancer Driver No 72 0.108 451 49 0.109 0
OTULIN OTULIN Q96BN8 Ubiquitin thioesterase otulin chr5 GO:1902494 Not Cancer Driver No 47 0.134 97 5 0.052 2
P3H3 P3H3 Q8IVL6 Prolyl 3-hydroxylase 3 chr12 GO:1902494 Not Cancer Driver No 84 0.114 307 40 0.13 0
P3H4_ENST00000393928 P3H4 Q92791 Endoplasmic reticulum protein SC65 chr17 GO:1902494 Not Cancer Driver No 46 0.105 82 9 0.11 0
P4HA1_ENST00000394890 P4HA1 P13674 Prolyl 4-hydroxylase subunit alpha-1 chr10 GO:1902494 Not Cancer Driver No 65 0.122 54 8 0.148 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 GO:1902494 Not Cancer Driver No 61 0.12 79 15 0.19 1
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:1902494 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAFAH1B2 PAFAH1B2 P68402 Platelet-activating factor acetylhydrolase IB subunit alpha2 chr11 GO:1902494 Census Yes 25 0.109 43 1 0.023 0
PAFAH1B3_ENST00000262890 PAFAH1B3 Q15102 Platelet-activating factor acetylhydrolase IB subunit alpha1 chr19 GO:1902494 Not Cancer Driver No 15 0.065 76 3 0.039 0
PAGR1 PAGR1 Q9BTK6 PAXIP1-associated glutamate-rich protein 1 chr16 GO:1902494 Not Cancer Driver No 16 0.063 254 16 0.063 0
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 GO:1902494 Not Cancer Driver No 200 0.147 1144 170 0.149 2
PARD6A PARD6A Q9NPB6 Partitioning defective 6 homolog alpha chr16 GO:1902494 Not Cancer Driver No 25 0.072 177 13 0.073 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 GO:1902494 Not Cancer Driver No 120 0.112 461 39 0.085 0
PBRM1_ENST00000296302 PBRM1 Q86U86 Protein polybromo-1 chr3 GO:1902494 Census, Compendium Yes 209 0.124 703 77 0.11 0
PCCA PCCA P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial chr13 GO:1902494 Not Cancer Driver No 102 0.14 42 14 0.333 16
PCCB_ENST00000251654 PCCB P05166 Propionyl-CoA carboxylase beta chain, mitochondrial chr3 GO:1902494 Not Cancer Driver No 59 0.109 64 12 0.188 25
PDCD6 PDCD6 O75340 Programmed cell death protein 6 chr5 GO:1902494 Not Cancer Driver No 21 0.11 24 1 0.042 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX GO:1902494 Not Cancer Driver No 70 0.179 43 6 0.14 20
PDHB PDHB P11177 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial chr3 GO:1902494 Not Cancer Driver No 32 0.089 4 0 0.0 2
PDHX PDHX O00330 Pyruvate dehydrogenase protein X component, mitochondrial chr11 GO:1902494 Not Cancer Driver No 62 0.124 179 28 0.156 0
PDK1_ENST00000282077 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 GO:1902494 Not Cancer Driver No 52 0.119 50 10 0.2 0
PDK2 PDK2 Q15119 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial chr17 GO:1902494 Not Cancer Driver No 45 0.111 35 4 0.114 0
PEF1 PEF1 Q9UBV8 Peflin chr1 GO:1902494 Not Cancer Driver No 44 0.155 122 20 0.164 0
PELP1_ENST00000574876 PELP1 Q8IZL8 Proline-, glutamic acid- and leucine-rich protein 1 chr17 GO:1902494 Not Cancer Driver No 134 0.119 610 82 0.134 0
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:1902494 Not Cancer Driver No 81 0.172 48 11 0.229 0
PFKL PFKL P17858 ATP-dependent 6-phosphofructokinase, liver type chr21 GO:1902494 Not Cancer Driver No 91 0.117 29 4 0.138 0
PFKM_ENST00000550924 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 GO:1902494 Not Cancer Driver No 80 0.103 70 8 0.114 9
PFKP PFKP Q01813 ATP-dependent 6-phosphofructokinase, platelet type chr10 GO:1902494 Not Cancer Driver No 133 0.17 43 10 0.233 0
PGGT1B PGGT1B P53609 Geranylgeranyl transferase type-1 subunit beta chr5 GO:1902494 Not Cancer Driver No 44 0.117 12 0 0.0 0
PHF10 PHF10 Q8WUB8 PHD finger protein 10 chr6 GO:1902494 Not Cancer Driver No 39 0.078 298 26 0.087 0
PHF12 PHF12 Q96QT6 PHD finger protein 12 chr17 GO:1902494 Not Cancer Driver No 107 0.107 619 68 0.11 0
PHF14 PHF14 O94880 PHD finger protein 14 chr7 GO:1902494 Not Cancer Driver No 102 0.115 565 56 0.099 0
PHF20 PHF20 Q9BVI0 PHD finger protein 20 chr20 GO:1902494 Not Cancer Driver No 130 0.128 667 82 0.123 0
PHF20L1 PHF20L1 A8MW92 PHD finger protein 20-like protein 1 chr8 GO:1902494 Not Cancer Driver No 163 0.16 645 87 0.135 0
PHKA1 PHKA1 P46020 Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform chrX GO:1902494 Not Cancer Driver No 228 0.186 188 43 0.229 1
PHKA2 PHKA2 P46019 Phosphorylase b kinase regulatory subunit alpha, liver isoform chrX GO:1902494 Not Cancer Driver No 199 0.161 193 37 0.192 17
PHKB PHKB Q93100 Phosphorylase b kinase regulatory subunit beta chr16 GO:1902494 Not Cancer Driver No 147 0.134 98 9 0.092 1
PHKG1_ENST00000297373 PHKG1 Q16816 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform chr7 GO:1902494 Not Cancer Driver No 58 0.15 23 4 0.174 0
PHKG2 PHKG2 P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform chr16 GO:1902494 Not Cancer Driver No 48 0.118 50 6 0.12 4
PIGA PIGA P37287 Phosphatidylinositol N-acetylglucosaminyltransferase subunit A chrX GO:1902494 Not Cancer Driver No 51 0.105 21 0 0.0 13
PIGC_ENST00000344529 PIGC Q92535 Phosphatidylinositol N-acetylglucosaminyltransferase subunit C chr1 GO:1902494 Not Cancer Driver No 29 0.098 0 0 0.0 2
PIGH PIGH Q14442 Phosphatidylinositol N-acetylglucosaminyltransferase subunit H chr14 GO:1902494 Not Cancer Driver No 12 0.064 1 0 0.0 1
PIGK PIGK Q92643 GPI-anchor transamidase chr1 GO:1902494 Not Cancer Driver No 54 0.137 37 9 0.243 5
PIGM PIGM Q9H3S5 GPI mannosyltransferase 1 chr1 GO:1902494 Not Cancer Driver No 33 0.078 0 0 0.0 0
PIGP PIGP P57054 Phosphatidylinositol N-acetylglucosaminyltransferase subunit P chr21 GO:1902494 Not Cancer Driver No 10 0.063 0 0 0.0 1
PIGQ PIGQ Q9BRB3 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q chr16 GO:1902494 Not Cancer Driver No 98 0.129 133 22 0.165 0
PIGS PIGS Q96S52 GPI transamidase component PIG-S chr17 GO:1902494 Not Cancer Driver No 59 0.106 32 4 0.125 2
PIGT PIGT Q969N2 GPI transamidase component PIG-T chr20 GO:1902494 Not Cancer Driver No 51 0.088 36 6 0.167 1
PIGU PIGU Q9H490 Phosphatidylinositol glycan anchor biosynthesis class U protein chr20 GO:1902494 Not Cancer Driver No 47 0.108 0 0 0.0 2
PIGY PIGY Q3MUY2 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y chr4 GO:1902494 Not Cancer Driver No 4 0.056 0 0 0.0 1
PIK3C3 PIK3C3 Q8NEB9 Phosphatidylinositol 3-kinase catalytic subunit type 3 chr18 GO:1902494 Not Cancer Driver No 127 0.143 191 34 0.178 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:1902494 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:1902494 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:1902494 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:1902494 Not Cancer Driver No 318 0.289 121 39 0.322 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:1902494 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 GO:1902494 Not Cancer Driver No 96 0.132 418 47 0.112 3
PIK3R4 PIK3R4 Q99570 Phosphoinositide 3-kinase regulatory subunit 4 chr3 GO:1902494 Not Cancer Driver No 193 0.142 315 45 0.143 0
PIK3R5 PIK3R5 Q8WYR1 Phosphoinositide 3-kinase regulatory subunit 5 chr17 GO:1902494 Not Cancer Driver No 143 0.163 316 55 0.174 1
PIK3R6_ENST00000614407 PIK3R6 Q5UE93 Phosphoinositide 3-kinase regulatory subunit 6 chr17 GO:1902494 Not Cancer Driver No 100 0.133 156 26 0.167 0
PLAU PLAU P00749 Urokinase-type plasminogen activator chr10 GO:1902494 Not Cancer Driver No 59 0.137 10 0 0.0 0
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 GO:1902494 Not Cancer Driver No 49 0.146 18 5 0.278 0
PLOD1 PLOD1 Q02809 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 chr1 GO:1902494 Not Cancer Driver No 86 0.118 12 0 0.0 5
PLRG1 PLRG1 O43660 Pleiotropic regulator 1 chr4 GO:1902494 Not Cancer Driver No 75 0.146 204 25 0.123 0
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:1902494 Not Cancer Driver No 86 0.11 115 10 0.087 2
POLA1_ENST00000379059 POLA1 P09884 DNA polymerase alpha catalytic subunit chrX GO:1902494 Not Cancer Driver No 185 0.127 347 45 0.13 3
POLA2 POLA2 Q14181 DNA polymerase alpha subunit B chr11 GO:1902494 Not Cancer Driver No 63 0.105 102 16 0.157 0
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 GO:1902494 Census, Compendium Yes 179 0.162 214 31 0.145 2
POLD2_ENST00000452185 POLD2 P49005 DNA polymerase delta subunit 2 chr7 GO:1902494 Not Cancer Driver No 49 0.104 65 3 0.046 0
POLD3 POLD3 Q15054 DNA polymerase delta subunit 3 chr11 GO:1902494 Not Cancer Driver No 51 0.109 326 39 0.12 0
POLD4 POLD4 Q9HCU8 DNA polymerase delta subunit 4 chr11 GO:1902494 Not Cancer Driver No 8 0.075 50 3 0.06 0
POLE3 POLE3 Q9NRF9 DNA polymerase epsilon subunit 3 chr9 GO:1902494 Not Cancer Driver No 11 0.075 117 9 0.077 0
POLE4 POLE4 Q9NR33 DNA polymerase epsilon subunit 4 chr2 GO:1902494 Not Cancer Driver No 4 0.034 45 1 0.022 0
POLG2 POLG2 Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial chr17 GO:1902494 Not Cancer Driver No 64 0.132 46 4 0.087 3
POLG_ENST00000442287 POLG P54098 DNA polymerase subunit gamma-1 chr15 GO:1902494 Census Yes 139 0.112 421 42 0.1 73
POLRMT POLRMT O00411 DNA-directed RNA polymerase, mitochondrial chr19 GO:1902494 Not Cancer Driver No 188 0.153 253 31 0.123 0
POP1_ENST00000349693 POP1 Q99575 Ribonucleases P/MRP protein subunit POP1 chr8 GO:1902494 Not Cancer Driver No 161 0.157 495 75 0.152 3
POP4 POP4 O95707 Ribonuclease P protein subunit p29 chr19 GO:1902494 Not Cancer Driver No 25 0.114 53 9 0.17 0
POP5 POP5 Q969H6 Ribonuclease P/MRP protein subunit POP5 chr12 GO:1902494 Not Cancer Driver No 17 0.104 9 2 0.222 0
POP7 POP7 O75817 Ribonuclease P protein subunit p20 chr7 GO:1902494 Not Cancer Driver No 20 0.143 59 13 0.22 0
PPCDC PPCDC Q96CD2 Phosphopantothenoylcysteine decarboxylase chr15 GO:1902494 Not Cancer Driver No 13 0.064 6 0 0.0 0
PPIE_ENST00000324379 PPIE Q9UNP9 Peptidyl-prolyl cis-trans isomerase E chr1 GO:1902494 Not Cancer Driver No 51 0.169 102 17 0.167 0
PPIL1 PPIL1 Q9Y3C6 Peptidyl-prolyl cis-trans isomerase-like 1 chr6 GO:1902494 Not Cancer Driver No 25 0.151 42 11 0.262 3
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 GO:1902494 Not Cancer Driver No 38 0.115 27 6 0.222 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 GO:1902494 Not Cancer Driver No 47 0.144 25 5 0.2 5
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 GO:1902494 Not Cancer Driver No 26 0.08 23 4 0.174 0
PPP1R10 PPP1R10 Q96QC0 Serine/threonine-protein phosphatase 1 regulatory subunit 10 chr6 GO:1902494 Not Cancer Driver No 114 0.121 798 100 0.125 0
PPP1R12A_ENST00000261207 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 GO:1902494 Not Cancer Driver No 107 0.104 821 89 0.108 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:1902494 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:1902494 Not Cancer Driver No 72 0.101 415 45 0.108 1
PPP1R3A PPP1R3A Q16821 Protein phosphatase 1 regulatory subunit 3A chr7 GO:1902494 Not Cancer Driver No 430 0.383 807 334 0.414 1
PPP1R3B PPP1R3B Q86XI6 Protein phosphatase 1 regulatory subunit 3B chr8 GO:1902494 Not Cancer Driver No 36 0.126 19 2 0.105 0
PPP1R3C PPP1R3C Q9UQK1 Protein phosphatase 1 regulatory subunit 3C chr10 GO:1902494 Not Cancer Driver No 37 0.117 16 0 0.0 0
PPP1R3D PPP1R3D O95685 Protein phosphatase 1 regulatory subunit 3D chr20 GO:1902494 Not Cancer Driver No 36 0.12 94 8 0.085 0
PPP1R3E PPP1R3E Q9H7J1 Protein phosphatase 1 regulatory subunit 3E chr14 GO:1902494 Not Cancer Driver No 1 0.004 182 0 0.0 0
PPP1R3F PPP1R3F Q6ZSY5 Protein phosphatase 1 regulatory subunit 3F chrX GO:1902494 Not Cancer Driver No 79 0.099 636 64 0.101 0
PPP1R3G PPP1R3G B7ZBB8 Protein phosphatase 1 regulatory subunit 3G chr6 GO:1902494 Not Cancer Driver No 14 0.039 198 11 0.056 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:1902494 Not Cancer Driver No 47 0.058 695 35 0.05 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 GO:1902494 Not Cancer Driver No 41 0.133 12 1 0.083 8
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 GO:1902494 Not Cancer Driver No 37 0.12 12 0 0.0 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:1902494 Census, Compendium Yes 179 0.304 0 0 0.0 4
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 GO:1902494 Not Cancer Driver No 72 0.12 17 1 0.059 0
PPP2R2A_ENST00000380737 PPP2R2A P63151 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform chr8 GO:1902494 Not Cancer Driver No 60 0.134 68 10 0.147 0
PPP2R2B_ENST00000394409 PPP2R2B Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform chr5 GO:1902494 Not Cancer Driver No 101 0.228 76 22 0.289 0
PPP2R2C_ENST00000382599 PPP2R2C Q9Y2T4 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform chr4 GO:1902494 Not Cancer Driver No 78 0.174 78 13 0.167 0
PPP2R2D PPP2R2D Q66LE6 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform chr10 GO:1902494 Not Cancer Driver No 50 0.11 65 9 0.138 0
PPP2R3A PPP2R3A Q06190 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha chr3 GO:1902494 Not Cancer Driver No 136 0.118 513 66 0.129 0
PPP2R3B PPP2R3B Q9Y5P8 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta chrX GO:1902494 Not Cancer Driver No 72 0.125 154 15 0.097 0
PPP2R5A PPP2R5A Q15172 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform chr1 GO:1902494 Not Cancer Driver No 55 0.113 93 5 0.054 0
PPP2R5B PPP2R5B Q15173 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform chr11 GO:1902494 Not Cancer Driver No 79 0.159 119 9 0.076 0
PPP2R5C_ENST00000334743 PPP2R5C Q13362 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform chr14 GO:1902494 Not Cancer Driver No 65 0.124 89 16 0.18 0
PPP2R5D PPP2R5D Q14738 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform chr6 GO:1902494 Not Cancer Driver No 64 0.106 178 13 0.073 4
PPP2R5E PPP2R5E Q16537 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform chr14 GO:1902494 Not Cancer Driver No 68 0.146 86 20 0.233 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:1902494 Compendium Yes 85 0.163 140 27 0.193 7
PPP3CB_ENST00000360663 PPP3CB P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform chr10 GO:1902494 Not Cancer Driver No 67 0.128 139 18 0.129 0
PPP3CC_ENST00000240139 PPP3CC P48454 Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform chr8 GO:1902494 Not Cancer Driver No 47 0.092 91 7 0.077 0
PPP3R1 PPP3R1 P63098 Calcineurin subunit B type 1 chr2 GO:1902494 Not Cancer Driver No 19 0.112 1 0 0.0 0
PPP4C_ENST00000561610 PPP4C P60510 Serine/threonine-protein phosphatase 4 catalytic subunit chr16 GO:1902494 Not Cancer Driver No 41 0.134 0 0 0.0 0
PPP4R1 PPP4R1 Q8TF05 Serine/threonine-protein phosphatase 4 regulatory subunit 1 chr18 GO:1902494 Not Cancer Driver No 92 0.097 304 20 0.066 0
PPP4R2 PPP4R2 Q9NY27 Serine/threonine-protein phosphatase 4 regulatory subunit 2 chr3 GO:1902494 Not Cancer Driver No 32 0.077 314 26 0.083 0
PPP4R3A_ENST00000554943 PPP4R3A Q6IN85 Serine/threonine-protein phosphatase 4 regulatory subunit 3A chr14 GO:1902494 Not Cancer Driver No 89 0.107 255 29 0.114 0
PPP4R3B PPP4R3B Q5MIZ7 Serine/threonine-protein phosphatase 4 regulatory subunit 3B chr2 GO:1902494 Not Cancer Driver No 100 0.118 240 33 0.138 0
PPP4R3C PPP4R3C Q6ZMV5 Protein PPP4R3C chrX GO:1902494 Not Cancer Driver No 1 0.001 184 0 0.0 0
PRAMEF6 PRAMEF6 Q5VXH4 PRAME family member 6 chr1 GO:1902494 Not Cancer Driver No 47 0.099 4 2 0.5 0
PRAME_ENST00000402697 PRAME P78395 Melanoma antigen preferentially expressed in tumors chr22 GO:1902494 Not Cancer Driver No 95 0.187 10 1 0.1 0
PRIM1 PRIM1 P49642 DNA primase small subunit chr12 GO:1902494 Not Cancer Driver No 31 0.074 22 1 0.045 0
PRIM2 PRIM2 P49643 DNA primase large subunit chr6 GO:1902494 Not Cancer Driver No 180 0.354 69 57 0.826 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:1902494 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:1902494 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKAB1 PRKAB1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 chr12 GO:1902494 Not Cancer Driver No 39 0.144 124 13 0.105 0
PRKAB2 PRKAB2 O43741 5'-AMP-activated protein kinase subunit beta-2 chr1 GO:1902494 Not Cancer Driver No 31 0.114 110 12 0.109 0
PRKAG1_ENST00000548065 PRKAG1 P54619 5'-AMP-activated protein kinase subunit gamma-1 chr12 GO:1902494 Not Cancer Driver No 35 0.106 25 2 0.08 0
PRKAG2 PRKAG2 Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 chr7 GO:1902494 Not Cancer Driver No 76 0.134 240 45 0.188 7
PRKAG3_ENST00000529249 PRKAG3 Q9UGI9 5'-AMP-activated protein kinase subunit gamma-3 chr2 GO:1902494 Not Cancer Driver No 74 0.151 144 25 0.174 0
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 GO:1902494 Census, Compendium Yes 39 0.102 66 11 0.167 17
PRKAR2A PRKAR2A P13861 cAMP-dependent protein kinase type II-alpha regulatory subunit chr3 GO:1902494 Not Cancer Driver No 37 0.092 149 13 0.087 0
PRKCI PRKCI P41743 Protein kinase C iota type chr3 GO:1902494 Not Cancer Driver No 110 0.185 120 16 0.133 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:1902494 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:1902494 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRKRA PRKRA O75569 Interferon-inducible double-stranded RNA-dependent protein kinase activator A chr2 GO:1902494 Not Cancer Driver No 41 0.131 104 12 0.115 1
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:1902494 Not Cancer Driver No 50 0.135 18 1 0.056 0
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:1902494 Not Cancer Driver No 83 0.13 72 6 0.083 0
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 GO:1902494 Not Cancer Driver No 71 0.141 109 16 0.147 0
PRPF31 PRPF31 Q8WWY3 U4/U6 small nuclear ribonucleoprotein Prp31 chr19 GO:1902494 Not Cancer Driver No 58 0.116 213 17 0.08 2
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 GO:1902494 Not Cancer Driver No 255 0.109 225 26 0.116 8
PRPS1 PRPS1 P60891 Ribose-phosphate pyrophosphokinase 1 chrX GO:1902494 Not Cancer Driver No 50 0.157 0 0 0.0 14
PRPS1L1_ENST00000638645 PRPS1L1 P21108 Ribose-phosphate pyrophosphokinase 3 chr7 GO:1902494 Not Cancer Driver No 83 0.261 0 0 0.0 0
PRPS2_ENST00000380668 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX GO:1902494 Not Cancer Driver No 56 0.176 4 1 0.25 0
PRPSAP2 PRPSAP2 O60256 Phosphoribosyl pyrophosphate synthase-associated protein 2 chr17 GO:1902494 Not Cancer Driver No 54 0.146 19 3 0.158 0
PSG9 PSG9 Q00887 Pregnancy-specific beta-1-glycoprotein 9 chr19 GO:1902494 Not Cancer Driver No 125 0.293 40 8 0.2 0
PSMA8 PSMA8 Q8TAA3 Proteasome subunit alpha-type 8 chr18 GO:1902494 Not Cancer Driver No 42 0.164 15 5 0.333 0
PSMB10 PSMB10 P40306 Proteasome subunit beta type-10 chr16 GO:1902494 Not Cancer Driver No 22 0.081 36 5 0.139 0
PSMB8 PSMB8 P28062 Proteasome subunit beta type-8 chr6 GO:1902494 Not Cancer Driver No 43 0.156 62 7 0.113 3
PSMB9 PSMB9 P28065 Proteasome subunit beta type-9 chr6 GO:1902494 Not Cancer Driver No 21 0.096 17 1 0.059 1
PSMC5 PSMC5 P62195 26S proteasome regulatory subunit 8 chr17 GO:1902494 Not Cancer Driver No 52 0.128 64 6 0.094 0
PSMC6_ENST00000606149 PSMC6 P62333 26S proteasome regulatory subunit 10B chr14 GO:1902494 Not Cancer Driver No 49 0.126 69 8 0.116 0
PSMD12 PSMD12 O00232 26S proteasome non-ATPase regulatory subunit 12 chr17 GO:1902494 Not Cancer Driver No 48 0.105 24 3 0.125 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 GO:1902494 Not Cancer Driver No 23 0.074 67 6 0.09 0
PSME4 PSME4 Q14997 Proteasome activator complex subunit 4 chr2 GO:1902494 Not Cancer Driver No 214 0.116 134 12 0.09 0
PTPA_ENST00000337738 PTPA Q15257 Serine/threonine-protein phosphatase 2A activator chr9 GO:1902494 Not Cancer Driver No 40 0.112 63 2 0.032 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:1902494 Not Cancer Driver No 16 0.082 39 4 0.103 0
PYDC1 PYDC1 Q8WXC3 Pyrin domain-containing protein 1 chr16 GO:1902494 Not Cancer Driver No 28 0.315 0 0 0.0 0
QPRT QPRT Q15274 Nicotinate-nucleotide pyrophosphorylase [carboxylating] chr16 GO:1902494 Not Cancer Driver No 29 0.098 7 1 0.143 0
RABGGTA RABGGTA Q92696 Geranylgeranyl transferase type-2 subunit alpha chr14 GO:1902494 Not Cancer Driver No 74 0.131 37 2 0.054 0
RABGGTB RABGGTB P53611 Geranylgeranyl transferase type-2 subunit beta chr1 GO:1902494 Not Cancer Driver No 50 0.151 4 1 0.25 0
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 GO:1902494 Not Cancer Driver No 59 0.119 328 43 0.131 0
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:1902494 Not Cancer Driver No 204 0.196 208 43 0.207 36
RAMAC RAMAC Q9BTL3 RNA guanine-N7 methyltransferase activating subunit chr15 GO:1902494 Not Cancer Driver No 14 0.119 118 14 0.119 0
RANBP2 RANBP2 P49792 E3 SUMO-protein ligase RanBP2 chr2 GO:1902494 Census, Compendium Yes 427 0.132 1387 177 0.128 3
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:1902494 Not Cancer Driver No 65 0.111 159 17 0.107 0
RB1CC1 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 GO:1902494 Not Cancer Driver No 202 0.127 578 75 0.13 0
RBBP4 RBBP4 Q09028 Histone-binding protein RBBP4 chr1 GO:1902494 Not Cancer Driver No 53 0.125 169 23 0.136 0
RBBP5 RBBP5 Q15291 Retinoblastoma-binding protein 5 chr1 GO:1902494 Not Cancer Driver No 57 0.106 218 19 0.087 0
RBBP7_ENST00000380087 RBBP7 Q16576 Histone-binding protein RBBP7 chrX GO:1902494 Not Cancer Driver No 67 0.158 138 19 0.138 0
RBCK1 RBCK1 Q9BYM8 RanBP-type and C3HC4-type zinc finger-containing protein 1 chr20 GO:1902494 Not Cancer Driver No 52 0.102 140 14 0.1 2
RBM15 RBM15 Q96T37 RNA-binding protein 15 chr1 GO:1902494 Census, Compendium Yes 118 0.121 686 91 0.133 0
RBM15B RBM15B Q8NDT2 Putative RNA-binding protein 15B chr3 GO:1902494 Not Cancer Driver No 76 0.085 597 48 0.08 0
RBM22 RBM22 Q9NW64 Pre-mRNA-splicing factor RBM22 chr5 GO:1902494 Not Cancer Driver No 51 0.121 214 29 0.136 0
RBM8A_ENST00000632555 RBM8A Q9Y5S9 RNA-binding protein 8A chr1 GO:1902494 Not Cancer Driver No 35 0.201 135 32 0.237 0
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 GO:1902494 Not Cancer Driver No 10 0.093 18 1 0.056 0
REV3L_ENST00000368802 REV3L O60673 DNA polymerase zeta catalytic subunit chr6 GO:1902494 Not Cancer Driver No 379 0.121 1665 211 0.127 0
RFC1 RFC1 P35251 Replication factor C subunit 1 chr4 GO:1902494 Not Cancer Driver No 147 0.128 674 82 0.122 0
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 GO:1902494 Not Cancer Driver No 58 0.16 50 8 0.16 0
RHBDD2 RHBDD2 Q6NTF9 Rhomboid domain-containing protein 2 chr7 GO:1902494 Not Cancer Driver No 48 0.132 120 23 0.192 0
RIOK1 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 GO:1902494 Not Cancer Driver No 69 0.121 301 37 0.123 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:1902494 Compendium Yes 82 0.122 277 39 0.141 4
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 GO:1902494 Not Cancer Driver No 40 0.119 203 22 0.108 0
RNF20 RNF20 Q5VTR2 E3 ubiquitin-protein ligase BRE1A chr9 GO:1902494 Not Cancer Driver No 126 0.129 561 64 0.114 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 GO:1902494 Not Cancer Driver No 142 0.132 319 45 0.141 0
RNF40 RNF40 O75150 E3 ubiquitin-protein ligase BRE1B chr16 GO:1902494 Not Cancer Driver No 132 0.132 645 80 0.124 0
RNF7 RNF7 Q9UBF6 RING-box protein 2 chr3 GO:1902494 Not Cancer Driver No 17 0.15 0 0 0.0 0
RNMT_ENST00000543302 RNMT O43148 mRNA cap guanine-N7 methyltransferase chr18 GO:1902494 Not Cancer Driver No 67 0.141 159 23 0.145 0
RPP14_ENST00000295959 RPP14 O95059 Ribonuclease P protein subunit p14 chr3 GO:1902494 Not Cancer Driver No 8 0.065 0 0 0.0 0
RPP21_ENST00000442966 RPP21 Q9H633 Ribonuclease P protein subunit p21 chr6 GO:1902494 Not Cancer Driver No 16 0.104 51 4 0.078 0
RPP25 RPP25 Q9BUL9 Ribonuclease P protein subunit p25 chr15 GO:1902494 Not Cancer Driver No 11 0.055 162 11 0.068 0
RPP30_ENST00000371703 RPP30 P78346 Ribonuclease P protein subunit p30 chr10 GO:1902494 Not Cancer Driver No 28 0.104 21 2 0.095 0
RPP38_ENST00000378202 RPP38 P78345 Ribonuclease P protein subunit p38 chr10 GO:1902494 Not Cancer Driver No 36 0.127 118 19 0.161 0
RPP40 RPP40 O75818 Ribonuclease P protein subunit p40 chr6 GO:1902494 Not Cancer Driver No 51 0.14 5 0 0.0 0
RRM1 RRM1 P23921 Ribonucleoside-diphosphate reductase large subunit chr11 GO:1902494 Not Cancer Driver No 74 0.093 41 7 0.171 0
RRM2_ENST00000641198 RRM2 P31350 Ribonucleoside-diphosphate reductase subunit M2 chr2 GO:1902494 Not Cancer Driver No 40 0.103 48 0 0.0 0
RSF1 RSF1 Q96T23 Remodeling and spacing factor 1 chr11 GO:1902494 Not Cancer Driver No 153 0.106 1170 130 0.111 0
RUVBL1 RUVBL1 Q9Y265 RuvB-like 1 chr3 GO:1902494 Not Cancer Driver No 54 0.118 67 7 0.104 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:1902494 Not Cancer Driver No 62 0.134 100 13 0.13 0
SAE1 SAE1 Q9UBE0 SUMO-activating enzyme subunit 1 chr19 GO:1902494 Not Cancer Driver No 39 0.113 90 6 0.067 0
SCLY SCLY Q96I15 Selenocysteine lyase chr2 GO:1902494 Not Cancer Driver No 49 0.11 169 11 0.065 0
SDHA SDHA P31040 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial chr5 GO:1902494 Census Yes 115 0.173 71 13 0.183 7
SDHB SDHB P21912 Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial chr1 GO:1902494 Census Yes 37 0.132 17 3 0.176 23
SDHC SDHC Q99643 Succinate dehydrogenase cytochrome b560 subunit, mitochondrial chr1 GO:1902494 Census Yes 16 0.095 0 0 0.0 0
SDHD SDHD O14521 Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial chr11 GO:1902494 Census Yes 22 0.138 0 0 0.0 10
SEC11A_ENST00000268220 SEC11A P67812 Signal peptidase complex catalytic subunit SEC11A chr15 GO:1902494 Not Cancer Driver No 20 0.112 0 0 0.0 0
SEC11C SEC11C Q9BY50 Signal peptidase complex catalytic subunit SEC11C chr18 GO:1902494 Not Cancer Driver No 24 0.125 3 0 0.0 0
SEL1L SEL1L Q9UBV2 Protein sel-1 homolog 1 chr14 GO:1902494 Not Cancer Driver No 95 0.12 187 18 0.096 0
SENP3_ENST00000429205 SENP3 Q9H4L4 Sentrin-specific protease 3 chr17 GO:1902494 Not Cancer Driver No 53 0.092 288 30 0.104 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:1902494 Not Cancer Driver No 74 0.154 147 26 0.177 0
SETD1A SETD1A O15047 Histone-lysine N-methyltransferase SETD1A chr16 GO:1902494 Not Cancer Driver No 223 0.131 1327 188 0.142 5
SETD1B SETD1B Q9UPS6 Histone-lysine N-methyltransferase SETD1B chr12 GO:1902494 Census, Compendium Yes 88 0.045 1479 61 0.041 4
SF3B1 SF3B1 O75533 Splicing factor 3B subunit 1 chr2 GO:1902494 Census, Compendium Yes 244 0.187 477 80 0.168 0
SGF29 SGF29 Q96ES7 SAGA-associated factor 29 chr16 GO:1902494 Not Cancer Driver No 31 0.106 131 17 0.13 0
SHARPIN SHARPIN Q9H0F6 Sharpin chr8 GO:1902494 Not Cancer Driver No 34 0.088 237 16 0.068 0
SHOC2 SHOC2 Q9UQ13 Leucine-rich repeat protein SHOC-2 chr10 GO:1902494 Not Cancer Driver No 55 0.095 110 12 0.109 2
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:1902494 Compendium Yes 172 0.135 617 73 0.118 0
SIN3B SIN3B O75182 Paired amphipathic helix protein Sin3b chr19 GO:1902494 Not Cancer Driver No 130 0.112 316 32 0.101 0
SINHCAF_ENST00000454658 SINHCAF Q9NP50 SIN3-HDAC complex-associated factor chr12 GO:1902494 Not Cancer Driver No 24 0.109 108 10 0.093 0
SKP1_ENST00000517625 SKP1 P63208 S-phase kinase-associated protein 1 chr5 GO:1902494 Not Cancer Driver No 19 0.117 95 17 0.179 0
SMARCA1_ENST00000371122 SMARCA1 P28370 Probable global transcription activator SNF2L1 chrX GO:1902494 Compendium Yes 143 0.136 309 41 0.133 0
SMARCA2 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 GO:1902494 Not Cancer Driver No 273 0.172 1009 160 0.159 42
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:1902494 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 GO:1902494 Not Cancer Driver No 116 0.11 363 48 0.132 0
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:1902494 Census, Compendium Yes 64 0.166 141 35 0.248 3
SMARCC1 SMARCC1 Q92922 SWI/SNF complex subunit SMARCC1 chr3 GO:1902494 Not Cancer Driver No 125 0.113 720 81 0.113 0
SMARCC2_ENST00000267064 SMARCC2 Q8TAQ2 SWI/SNF complex subunit SMARCC2 chr12 GO:1902494 Not Cancer Driver No 175 0.144 876 133 0.152 4
SMARCD1 SMARCD1 Q96GM5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 chr12 GO:1902494 Census, Compendium Yes 48 0.093 216 18 0.083 2
SMARCD3 SMARCD3 Q6STE5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 chr7 GO:1902494 Not Cancer Driver No 64 0.133 213 18 0.085 0
SMARCE1 SMARCE1 Q969G3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 chr17 GO:1902494 Census Yes 47 0.114 332 36 0.108 2
SMC5 SMC5 Q8IY18 Structural maintenance of chromosomes protein 5 chr9 GO:1902494 Not Cancer Driver No 126 0.114 378 43 0.114 0
SMC6_ENST00000351948 SMC6 Q96SB8 Structural maintenance of chromosomes protein 6 chr2 GO:1902494 Not Cancer Driver No 128 0.117 458 57 0.124 0
SMCR8 SMCR8 Q8TEV9 Guanine nucleotide exchange protein SMCR8 chr17 GO:1902494 Not Cancer Driver No 107 0.114 357 38 0.106 0
SNRNP200 SNRNP200 O75643 U5 small nuclear ribonucleoprotein 200 kDa helicase chr2 GO:1902494 Not Cancer Driver No 237 0.111 270 37 0.137 11
SNRNP40 SNRNP40 Q96DI7 U5 small nuclear ribonucleoprotein 40 kDa protein chr1 GO:1902494 Not Cancer Driver No 41 0.115 50 10 0.2 0
SNRPA1 SNRPA1 P09661 U2 small nuclear ribonucleoprotein A' chr15 GO:1902494 Not Cancer Driver No 33 0.129 93 14 0.151 0
SNRPB SNRPB P14678 Small nuclear ribonucleoprotein-associated proteins B and B' chr20 GO:1902494 Not Cancer Driver No 39 0.163 182 34 0.187 4
SNRPB2_ENST00000377943 SNRPB2 P08579 U2 small nuclear ribonucleoprotein B'' chr20 GO:1902494 Not Cancer Driver No 18 0.08 100 7 0.07 0
SNRPD1 SNRPD1 P62314 Small nuclear ribonucleoprotein Sm D1 chr18 GO:1902494 Not Cancer Driver No 10 0.084 80 4 0.05 0
SNRPD2_ENST00000588301 SNRPD2 P62316 Small nuclear ribonucleoprotein Sm D2 chr19 GO:1902494 Not Cancer Driver No 19 0.161 67 12 0.179 0
SNRPD3 SNRPD3 P62318 Small nuclear ribonucleoprotein Sm D3 chr22 GO:1902494 Not Cancer Driver No 20 0.159 43 13 0.302 0
SNRPE SNRPE P62304 Small nuclear ribonucleoprotein E chr1 GO:1902494 Not Cancer Driver No 16 0.174 0 0 0.0 1
SNRPF SNRPF P62306 Small nuclear ribonucleoprotein F chr12 GO:1902494 Not Cancer Driver No 4 0.047 10 0 0.0 0
SNRPG_ENST00000272348 SNRPG P62308 Small nuclear ribonucleoprotein G chr2 GO:1902494 Not Cancer Driver No 8 0.105 9 3 0.333 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 GO:1902494 Not Cancer Driver No 62 0.116 488 56 0.115 0
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:1902494 Compendium Yes 197 0.148 458 62 0.135 38
SPCS1 SPCS1 Q9Y6A9 Signal peptidase complex subunit 1 chr3 GO:1902494 Not Cancer Driver No 18 0.107 81 9 0.111 0
SPCS2 SPCS2 Q15005 Signal peptidase complex subunit 2 chr11 GO:1902494 Not Cancer Driver No 17 0.075 0 0 0.0 0
SPCS3 SPCS3 P61009 Signal peptidase complex subunit 3 chr4 GO:1902494 Not Cancer Driver No 25 0.139 0 0 0.0 0
SPG7 SPG7 Q9UQ90 Paraplegin chr16 GO:1902494 Not Cancer Driver No 97 0.122 181 29 0.16 4
SPOP SPOP O43791 Speckle-type POZ protein chr17 GO:1902494 Census, Compendium Yes 147 0.393 25 5 0.2 6
SPOPL SPOPL Q6IQ16 Speckle-type POZ protein-like chr2 GO:1902494 Not Cancer Driver No 87 0.222 40 14 0.35 0
SPTLC1 SPTLC1 O15269 Serine palmitoyltransferase 1 chr9 GO:1902494 Not Cancer Driver No 50 0.106 27 5 0.185 5
SPTLC2 SPTLC2 O15270 Serine palmitoyltransferase 2 chr14 GO:1902494 Not Cancer Driver No 72 0.128 9 2 0.222 5
SPTLC3 SPTLC3 Q9NUV7 Serine palmitoyltransferase 3 chr20 GO:1902494 Not Cancer Driver No 135 0.245 40 12 0.3 0
SPTSSA SPTSSA Q969W0 Serine palmitoyltransferase small subunit A chr14 GO:1902494 Not Cancer Driver No 9 0.127 0 0 0.0 0
SPTSSB_ENST00000620149 SPTSSB Q8NFR3 Serine palmitoyltransferase small subunit B chr3 GO:1902494 Not Cancer Driver No 15 0.197 0 0 0.0 0
SRCAP SRCAP Q6ZRS2 Helicase SRCAP chr16 GO:1902494 Not Cancer Driver No 438 0.136 2534 340 0.134 0
SRRM2 SRRM2 Q9UQ35 Serine/arginine repetitive matrix protein 2 chr16 GO:1902494 Not Cancer Driver No 433 0.157 2748 431 0.157 0
SS18 SS18 Q15532 Protein SSXT chr18 GO:1902494 Census Yes 52 0.124 416 52 0.125 0
SS18L1 SS18L1 O75177 Calcium-responsive transactivator chr20 GO:1902494 Census Yes 53 0.134 356 48 0.135 0
STT3A_ENST00000529196 STT3A P46977 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A chr11 GO:1902494 Not Cancer Driver No 82 0.116 27 2 0.074 1
STT3B STT3B Q8TCJ2 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B chr3 GO:1902494 Not Cancer Driver No 60 0.073 136 9 0.066 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:1902494 Not Cancer Driver No 35 0.116 112 14 0.125 12
SUCLA2 SUCLA2 Q9P2R7 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial chr13 GO:1902494 Not Cancer Driver No 51 0.11 46 6 0.13 3
SUCLG1 SUCLG1 P53597 Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial chr2 GO:1902494 Not Cancer Driver No 48 0.139 57 8 0.14 3
SUCLG2_ENST00000307227 SUCLG2 Q96I99 Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial chr3 GO:1902494 Not Cancer Driver No 48 0.111 12 2 0.167 0
SUDS3 SUDS3 Q9H7L9 Sin3 histone deacetylase corepressor complex component SDS3 chr12 GO:1902494 Not Cancer Driver No 35 0.107 249 28 0.112 0
SUMO4 SUMO4 Q6EEV6 Small ubiquitin-related modifier 4 chr6 GO:1902494 Not Cancer Driver No 7 0.074 69 4 0.058 0
SUPT3H_ENST00000371459 SUPT3H O75486 Transcription initiation protein SPT3 homolog chr6 GO:1902494 Not Cancer Driver No 49 0.155 49 4 0.082 0
SUPV3L1 SUPV3L1 Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial chr10 GO:1902494 Not Cancer Driver No 72 0.092 140 12 0.086 0
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 GO:1902494 Census, Compendium Yes 83 0.112 483 46 0.095 3
SYF2 SYF2 O95926 Pre-mRNA-splicing factor SYF2 chr1 GO:1902494 Not Cancer Driver No 26 0.107 173 17 0.098 0
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 GO:1902494 Not Cancer Driver No 63 0.102 284 32 0.113 0
TADA3 TADA3 O75528 Transcriptional adapter 3 chr3 GO:1902494 Not Cancer Driver No 54 0.125 353 43 0.122 0
TAF10 TAF10 Q12962 Transcription initiation factor TFIID subunit 10 chr11 GO:1902494 Not Cancer Driver No 17 0.078 131 4 0.031 0
TAF12_ENST00000373824 TAF12 Q16514 Transcription initiation factor TFIID subunit 12 chr1 GO:1902494 Not Cancer Driver No 11 0.068 107 7 0.065 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:1902494 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TAF2 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 GO:1902494 Not Cancer Driver No 129 0.108 241 34 0.141 1
TAF4 TAF4 O00268 Transcription initiation factor TFIID subunit 4 chr20 GO:1902494 Not Cancer Driver No 112 0.103 975 96 0.098 0
TAF5 TAF5 Q15542 Transcription initiation factor TFIID subunit 5 chr10 GO:1902494 Not Cancer Driver No 61 0.076 294 12 0.041 0
TAF5L TAF5L O75529 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L chr1 GO:1902494 Not Cancer Driver No 87 0.148 69 11 0.159 0
TAF6L TAF6L Q9Y6J9 TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L chr11 GO:1902494 Not Cancer Driver No 64 0.103 246 20 0.081 0
TAF6_ENST00000344095 TAF6 P49848 Transcription initiation factor TFIID subunit 6 chr7 GO:1902494 Not Cancer Driver No 79 0.117 288 32 0.111 2
TAF7 TAF7 Q15545 Transcription initiation factor TFIID subunit 7 chr5 GO:1902494 Not Cancer Driver No 40 0.115 258 31 0.12 0
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 GO:1902494 Not Cancer Driver No 25 0.095 203 19 0.094 0
TAF9B TAF9B Q9HBM6 Transcription initiation factor TFIID subunit 9B chrX GO:1902494 Not Cancer Driver No 48 0.191 189 34 0.18 0
TARBP2 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 GO:1902494 Not Cancer Driver No 45 0.123 203 22 0.108 0
TENT2_ENST00000428308 TENT2 Q6PIY7 Poly(A) RNA polymerase GLD2 chr5 GO:1902494 Not Cancer Driver No 65 0.134 75 15 0.2 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:1902494 Census Yes 110 0.097 212 16 0.075 31
TEX10 TEX10 Q9NXF1 Testis-expressed protein 10 chr9 GO:1902494 Not Cancer Driver No 115 0.124 103 12 0.117 0
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:1902494 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:1902494 Census, Compendium Yes 106 0.187 60 16 0.267 25
THBD THBD P07204 Thrombomodulin chr20 GO:1902494 Not Cancer Driver No 39 0.068 51 3 0.059 9
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:1902494 Not Cancer Driver No 92 0.129 443 66 0.149 1
TMEM258 TMEM258 P61165 Transmembrane protein 258 chr11 GO:1902494 Not Cancer Driver No 13 0.165 0 0 0.0 0
TNFAIP1 TNFAIP1 Q13829 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 chr17 GO:1902494 Not Cancer Driver No 35 0.111 39 5 0.128 0
TOX4_ENST00000448790 TOX4 O94842 TOX high mobility group box family member 4 chr14 GO:1902494 Not Cancer Driver No 69 0.111 562 62 0.11 0
TRIM40_ENST00000376724 TRIM40 Q6P9F5 E3 ubiquitin ligase TRIM40 chr6 GO:1902494 Not Cancer Driver No 44 0.171 84 12 0.143 0
TRMT10C TRMT10C Q7L0Y3 tRNA methyltransferase 10 homolog C chr3 GO:1902494 Not Cancer Driver No 56 0.139 59 10 0.169 2
TRMT6 TRMT6 Q9UJA5 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 chr20 GO:1902494 Not Cancer Driver No 42 0.085 208 17 0.082 0
TRMT61A TRMT61A Q96FX7 tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A chr14 GO:1902494 Not Cancer Driver No 16 0.055 74 9 0.122 0
TRMT61B TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 GO:1902494 Not Cancer Driver No 48 0.101 123 10 0.081 0
TRPC4AP TRPC4AP Q8TEL6 Short transient receptor potential channel 4-associated protein chr20 GO:1902494 Not Cancer Driver No 84 0.105 70 7 0.1 0
TRRAP TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 GO:1902494 Census, Compendium Yes 554 0.144 402 59 0.147 8
TSEN2 TSEN2 Q8NCE0 tRNA-splicing endonuclease subunit Sen2 chr3 GO:1902494 Not Cancer Driver No 54 0.116 153 17 0.111 1
TSEN34_ENST00000396383 TSEN34 Q9BSV6 tRNA-splicing endonuclease subunit Sen34 chr19 GO:1902494 Not Cancer Driver No 40 0.129 176 22 0.125 1
TSEN54 TSEN54 Q7Z6J9 tRNA-splicing endonuclease subunit Sen54 chr17 GO:1902494 Not Cancer Driver No 44 0.084 279 29 0.104 4
TSN TSN Q15631 Translin chr2 GO:1902494 Not Cancer Driver No 30 0.132 0 0 0.0 0
TSNAX TSNAX Q99598 Translin-associated protein X chr1 GO:1902494 Not Cancer Driver No 23 0.079 68 3 0.044 0
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 GO:1902494 Not Cancer Driver No 84 0.131 219 33 0.151 0
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX GO:1902494 Compendium Yes 35 0.23 67 13 0.194 2
UBE2B UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:1902494 Not Cancer Driver No 13 0.086 68 6 0.088 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 GO:1902494 Not Cancer Driver No 16 0.101 16 3 0.188 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 GO:1902494 Not Cancer Driver No 25 0.164 24 3 0.125 0
UBE2U_ENST00000611228 UBE2U Q5VVX9 Ubiquitin-conjugating enzyme E2 U chr1 GO:1902494 Not Cancer Driver No 38 0.118 66 1 0.015 0
UBE2V1_ENST00000371674 UBE2V1 Q13404 Ubiquitin-conjugating enzyme E2 variant 1 chr20 GO:1902494 Not Cancer Driver No 19 0.129 51 5 0.098 0
UBE2V2 UBE2V2 Q15819 Ubiquitin-conjugating enzyme E2 variant 2 chr8 GO:1902494 Not Cancer Driver No 22 0.152 76 12 0.158 0
UCHL5 UCHL5 Q9Y5K5 Ubiquitin carboxyl-terminal hydrolase isozyme L5 chr1 GO:1902494 Not Cancer Driver No 33 0.1 41 7 0.171 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:1902494 Not Cancer Driver No 142 0.135 588 77 0.131 0
USP33_ENST00000357428 USP33 Q8TEY7 Ubiquitin carboxyl-terminal hydrolase 33 chr1 GO:1902494 Not Cancer Driver No 138 0.146 256 48 0.188 0
UTY_ENST00000331397 UTY O14607 Histone demethylase UTY chrY GO:1902494 Not Cancer Driver No 38 0.028 564 21 0.037 0
UXS1_ENST00000409501 UXS1 Q8NBZ7 UDP-glucuronic acid decarboxylase 1 chr2 GO:1902494 Not Cancer Driver No 70 0.167 69 9 0.13 0
VAC14 VAC14 Q08AM6 Protein VAC14 homolog chr16 GO:1902494 Not Cancer Driver No 97 0.124 116 19 0.164 3
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 GO:1902494 Not Cancer Driver No 211 0.116 631 93 0.147 0
WDR4 WDR4 P57081 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 chr21 GO:1902494 Not Cancer Driver No 37 0.09 49 4 0.082 2
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 GO:1902494 Not Cancer Driver No 30 0.09 35 3 0.086 0
WDR5B WDR5B Q86VZ2 WD repeat-containing protein 5B chr3 GO:1902494 Not Cancer Driver No 35 0.106 29 5 0.172 0
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 GO:1902494 Not Cancer Driver No 30 0.088 41 2 0.049 0
WDR82 WDR82 Q6UXN9 WD repeat-containing protein 82 chr3 GO:1902494 Not Cancer Driver No 35 0.112 0 0 0.0 0
WTAP_ENST00000621533 WTAP Q15007 Pre-mRNA-splicing regulator WTAP chr6 GO:1902494 Not Cancer Driver No 60 0.152 305 50 0.164 0
XAB2 XAB2 Q9HCS7 Pre-mRNA-splicing factor SYF1 chr19 GO:1902494 Not Cancer Driver No 128 0.15 127 17 0.134 0
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:1902494 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:1902494 Not Cancer Driver No 66 0.108 140 12 0.086 0
YEATS2 YEATS2 Q9ULM3 YEATS domain-containing protein 2 chr3 GO:1902494 Not Cancer Driver No 170 0.12 983 124 0.126 0
YJU2 YJU2 Q9BW85 Splicing factor YJU2 chr19 GO:1902494 Not Cancer Driver No 29 0.09 233 13 0.056 0
ZC3H13 ZC3H13 Q5T200 Zinc finger CCCH domain-containing protein 13 chr13 GO:1902494 Not Cancer Driver No 250 0.15 1443 224 0.155 0
ZDHHC9_ENST00000371064 ZDHHC9 Q9Y397 Palmitoyltransferase ZDHHC9 chrX GO:1902494 Not Cancer Driver No 52 0.143 84 6 0.071 2
ZER1 ZER1 Q7Z7L7 Protein zer-1 homolog chr9 GO:1902494 Not Cancer Driver No 81 0.106 34 7 0.206 0
ZNFX1_ENST00000371752 ZNFX1 Q9P2E3 NFX1-type zinc finger-containing protein 1 chr20 GO:1902494 Not Cancer Driver No 228 0.119 354 49 0.138 0
ZNHIT1 ZNHIT1 O43257 Zinc finger HIT domain-containing protein 1 chr7 GO:1902494 Not Cancer Driver No 34 0.221 85 16 0.188 0
ZSWIM4 ZSWIM4 Q9H7M6 Zinc finger SWIM domain-containing protein 4 chr19 GO:1902494 Not Cancer Driver No 135 0.137 117 12 0.103 0
ZSWIM5 ZSWIM5 Q9P217 Zinc finger SWIM domain-containing protein 5 chr1 GO:1902494 Not Cancer Driver No 122 0.103 218 14 0.064 0
ZSWIM6 ZSWIM6 Q9HCJ5 Zinc finger SWIM domain-containing protein 6 chr5 GO:1902494 Not Cancer Driver No 64 0.053 244 7 0.029 1
ZSWIM8_ENST00000605216 ZSWIM8 A7E2V4 Zinc finger SWIM domain-containing protein 8 chr10 GO:1902494 Not Cancer Driver No 204 0.111 877 103 0.117 0
ZYG11A ZYG11A Q6WRX3 Protein zyg-11 homolog A chr1 GO:1902494 Not Cancer Driver No 52 0.069 7 0 0.0 0
ZYG11B ZYG11B Q9C0D3 Protein zyg-11 homolog B chr1 GO:1902494 Not Cancer Driver No 88 0.118 30 7 0.233 0