Total number of protein in "GO:1901981" GO term: 98
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAP2 | ADAP2 | Q9NPF8 | Arf-GAP with dual PH domain-containing protein 2 | chr17 | GO:1901981 | Not Cancer Driver | No | 42 | 0.11 | 30 | 5 | 0.167 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:1901981 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| ANKFY1_ENST00000341657 | ANKFY1 | Q9P2R3 | Rabankyrin-5 | chr17 | GO:1901981 | Not Cancer Driver | No | 109 | 0.093 | 185 | 29 | 0.157 | 0 |
| ARAP1 | ARAP1 | Q96P48 | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 | chr11 | GO:1901981 | Not Cancer Driver | No | 152 | 0.105 | 401 | 28 | 0.07 | 0 |
| ARAP2 | ARAP2 | Q8WZ64 | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 | chr4 | GO:1901981 | Not Cancer Driver | No | 289 | 0.17 | 449 | 86 | 0.192 | 0 |
| ARAP3 | ARAP3 | Q8WWN8 | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 | chr5 | GO:1901981 | Not Cancer Driver | No | 179 | 0.116 | 576 | 68 | 0.118 | 0 |
| ARFIP1 | ARFIP1 | P53367 | Arfaptin-1 | chr4 | GO:1901981 | Not Cancer Driver | No | 43 | 0.115 | 145 | 19 | 0.131 | 0 |
| ARFIP2_ENST00000254584 | ARFIP2 | P53365 | Arfaptin-2 | chr11 | GO:1901981 | Not Cancer Driver | No | 37 | 0.109 | 144 | 15 | 0.104 | 0 |
| ARHGAP32 | ARHGAP32 | A7KAX9 | Rho GTPase-activating protein 32 | chr11 | GO:1901981 | Not Cancer Driver | No | 268 | 0.128 | 1476 | 193 | 0.131 | 0 |
| ARHGAP9_ENST00000393791 | ARHGAP9 | Q9BRR9 | Rho GTPase-activating protein 9 | chr12 | GO:1901981 | Not Cancer Driver | No | 123 | 0.164 | 408 | 51 | 0.125 | 0 |
| ASAP1 | ASAP1 | Q9ULH1 | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 | chr8 | GO:1901981 | Not Cancer Driver | No | 183 | 0.162 | 584 | 108 | 0.185 | 0 |
| ATP13A2 | ATP13A2 | Q9NQ11 | Polyamine-transporting ATPase 13A2 | chr1 | GO:1901981 | Not Cancer Driver | No | 152 | 0.129 | 121 | 10 | 0.083 | 9 |
| BTK_ENST00000308731 | BTK | Q06187 | Tyrosine-protein kinase BTK | chrX | GO:1901981 | Census, Compendium | Yes | 147 | 0.223 | 114 | 27 | 0.237 | 110 |
| CLVS1 | CLVS1 | Q8IUQ0 | Clavesin-1 | chr8 | GO:1901981 | Not Cancer Driver | No | 121 | 0.342 | 68 | 16 | 0.235 | 0 |
| CLVS2 | CLVS2 | Q5SYC1 | Clavesin-2 | chr6 | GO:1901981 | Not Cancer Driver | No | 123 | 0.376 | 79 | 30 | 0.38 | 0 |
| COL4A3BP_ENST00000261415 | CERT1 | Q9Y5P4 | Ceramide transfer protein | chr5 | GO:1901981 | Not Cancer Driver | No | 73 | 0.117 | 215 | 23 | 0.107 | 2 |
| COMMD1 | COMMD1 | Q8N668 | COMM domain-containing protein 1 | chr2 | GO:1901981 | Not Cancer Driver | No | 21 | 0.111 | 17 | 0 | 0.0 | 0 |
| CYTH3_ENST00000396741 | CYTH3 | O43739 | Cytohesin-3 | chr7 | GO:1901981 | Not Cancer Driver | No | 49 | 0.122 | 96 | 12 | 0.125 | 0 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:1901981 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
| DAPP1 | DAPP1 | Q9UN19 | Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide | chr4 | GO:1901981 | Not Cancer Driver | No | 50 | 0.179 | 40 | 9 | 0.225 | 0 |
| DENND1A | DENND1A | Q8TEH3 | DENN domain-containing protein 1A | chr9 | GO:1901981 | Not Cancer Driver | No | 117 | 0.116 | 589 | 76 | 0.129 | 0 |
| DENND1B | DENND1B | Q6P3S1 | DENN domain-containing protein 1B | chr1 | GO:1901981 | Not Cancer Driver | No | 69 | 0.089 | 299 | 19 | 0.064 | 0 |
| DENND1C | DENND1C | Q8IV53 | DENN domain-containing protein 1C | chr19 | GO:1901981 | Not Cancer Driver | No | 102 | 0.127 | 369 | 54 | 0.146 | 0 |
| FCHSD2 | FCHSD2 | O94868 | F-BAR and double SH3 domains protein 2 | chr11 | GO:1901981 | Not Cancer Driver | No | 61 | 0.082 | 391 | 30 | 0.077 | 0 |
| FERMT2_ENST00000395631 | FERMT2 | Q96AC1 | Fermitin family homolog 2 | chr14 | GO:1901981 | Not Cancer Driver | No | 71 | 0.104 | 101 | 10 | 0.099 | 0 |
| FGD2 | FGD2 | Q7Z6J4 | FYVE, RhoGEF and PH domain-containing protein 2 | chr6 | GO:1901981 | Not Cancer Driver | No | 113 | 0.173 | 158 | 26 | 0.165 | 0 |
| FUNDC2 | FUNDC2 | Q9BWH2 | FUN14 domain-containing protein 2 | chrX | GO:1901981 | Not Cancer Driver | No | 28 | 0.148 | 34 | 3 | 0.088 | 0 |
| GAB2 | GAB2 | Q9UQC2 | GRB2-associated-binding protein 2 | chr11 | GO:1901981 | Not Cancer Driver | No | 85 | 0.126 | 537 | 73 | 0.136 | 0 |
| GAP43_ENST00000305124 | GAP43 | P17677 | Neuromodulin | chr3 | GO:1901981 | Not Cancer Driver | No | 79 | 0.332 | 238 | 79 | 0.332 | 0 |
| GBF1 | GBF1 | Q92538 | Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 | chr10 | GO:1901981 | Not Cancer Driver | No | 216 | 0.116 | 669 | 76 | 0.114 | 0 |
| GOLPH3 | GOLPH3 | Q9H4A6 | Golgi phosphoprotein 3 | chr5 | GO:1901981 | Not Cancer Driver | No | 41 | 0.138 | 72 | 1 | 0.014 | 0 |
| GOLPH3L | GOLPH3L | Q9H4A5 | Golgi phosphoprotein 3-like | chr1 | GO:1901981 | Not Cancer Driver | No | 24 | 0.084 | 81 | 12 | 0.148 | 0 |
| GSDMA | GSDMA | Q96QA5 | Gasdermin-A | chr17 | GO:1901981 | Not Cancer Driver | No | 67 | 0.151 | 87 | 15 | 0.172 | 0 |
| GSDMB | GSDMB | Q8TAX9 | Gasdermin-B | chr17 | GO:1901981 | Not Cancer Driver | No | 50 | 0.12 | 84 | 11 | 0.131 | 0 |
| GSDMC | GSDMC | Q9BYG8 | Gasdermin-C | chr8 | GO:1901981 | Not Cancer Driver | No | 125 | 0.246 | 0 | 0 | 0.0 | 0 |
| GSDMD_ENST00000262580 | GSDMD | P57764 | Gasdermin-D | chr8 | GO:1901981 | Not Cancer Driver | No | 47 | 0.097 | 156 | 16 | 0.103 | 0 |
| HIP1 | HIP1 | O00291 | Huntingtin-interacting protein 1 | chr7 | GO:1901981 | Census, Compendium | Yes | 137 | 0.132 | 510 | 70 | 0.137 | 0 |
| HIP1R | HIP1R | O75146 | Huntingtin-interacting protein 1-related protein | chr12 | GO:1901981 | Not Cancer Driver | No | 94 | 0.088 | 524 | 34 | 0.065 | 0 |
| IQGAP1 | IQGAP1 | P46940 | Ras GTPase-activating-like protein IQGAP1 | chr15 | GO:1901981 | Not Cancer Driver | No | 183 | 0.11 | 351 | 35 | 0.1 | 0 |
| IQGAP2 | IQGAP2 | Q13576 | Ras GTPase-activating-like protein IQGAP2 | chr5 | GO:1901981 | Not Cancer Driver | No | 237 | 0.15 | 255 | 50 | 0.196 | 0 |
| JPH2 | JPH2 | Q9BR39 | Junctophilin-2 | chr20 | GO:1901981 | Not Cancer Driver | No | 137 | 0.197 | 542 | 97 | 0.179 | 4 |
| KIF16B_ENST00000354981 | KIF16B | Q96L93 | Kinesin-like protein KIF16B | chr20 | GO:1901981 | Not Cancer Driver | No | 248 | 0.188 | 436 | 74 | 0.17 | 0 |
| LANCL2 | LANCL2 | Q9NS86 | LanC-like protein 2 | chr7 | GO:1901981 | Not Cancer Driver | No | 71 | 0.158 | 44 | 5 | 0.114 | 0 |
| MAPKAP1 | MAPKAP1 | Q9BPZ7 | Target of rapamycin complex 2 subunit MAPKAP1 | chr9 | GO:1901981 | Not Cancer Driver | No | 70 | 0.134 | 173 | 25 | 0.145 | 0 |
| MYO10 | MYO10 | Q9HD67 | Unconventional myosin-X | chr5 | GO:1901981 | Not Cancer Driver | No | 296 | 0.144 | 418 | 59 | 0.141 | 0 |
| MYO1B | MYO1B | O43795 | Unconventional myosin-Ib | chr2 | GO:1901981 | Not Cancer Driver | No | 144 | 0.127 | 34 | 4 | 0.118 | 0 |
| MYO1G | MYO1G | B0I1T2 | Unconventional myosin-Ig | chr7 | GO:1901981 | Not Cancer Driver | No | 125 | 0.123 | 117 | 12 | 0.103 | 0 |
| NRGN | NRGN | Q92686 | Neurogranin | chr11 | GO:1901981 | Not Cancer Driver | No | 5 | 0.064 | 76 | 5 | 0.066 | 0 |
| OBSCN_ENST00000422127 | OBSCN | Q5VST9 | Obscurin | chr1 | GO:1901981 | Not Cancer Driver | No | 1208 | 0.152 | 2623 | 368 | 0.14 | 0 |
| OGT | OGT | O15294 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | chrX | GO:1901981 | Not Cancer Driver | No | 156 | 0.149 | 89 | 16 | 0.18 | 2 |
| OSBP | OSBP | P22059 | Oxysterol-binding protein 1 | chr11 | GO:1901981 | Not Cancer Driver | No | 83 | 0.103 | 386 | 39 | 0.101 | 0 |
| OSBPL5 | OSBPL5 | Q9H0X9 | Oxysterol-binding protein-related protein 5 | chr11 | GO:1901981 | Not Cancer Driver | No | 100 | 0.114 | 444 | 43 | 0.097 | 0 |
| OSBPL8 | OSBPL8 | Q9BZF1 | Oxysterol-binding protein-related protein 8 | chr12 | GO:1901981 | Not Cancer Driver | No | 105 | 0.118 | 401 | 37 | 0.092 | 0 |
| PARD3 | PARD3 | Q8TEW0 | Partitioning defective 3 homolog | chr10 | GO:1901981 | Not Cancer Driver | No | 200 | 0.147 | 1144 | 170 | 0.149 | 2 |
| PHLDA1_ENST00000619060 | PHLDA1 | Q8WV24 | Pleckstrin homology-like domain family A member 1 | chr12 | GO:1901981 | Not Cancer Driver | No | 51 | 0.127 | 311 | 42 | 0.135 | 0 |
| PHLDA2_ENST00000645523 | PHLDA2 | Q53GA4 | Pleckstrin homology-like domain family A member 2 | chr11 | GO:1901981 | Not Cancer Driver | No | 12 | 0.079 | 58 | 2 | 0.034 | 0 |
| PHLDA3 | PHLDA3 | Q9Y5J5 | Pleckstrin homology-like domain family A member 3 | chr1 | GO:1901981 | Not Cancer Driver | No | 20 | 0.157 | 0 | 0 | 0.0 | 0 |
| PIRT | PIRT | P0C851 | Phosphoinositide-interacting protein | chr17 | GO:1901981 | Not Cancer Driver | No | 24 | 0.175 | 3 | 1 | 0.333 | 0 |
| PLA2G4A | PLA2G4A | P47712 | Cytosolic phospholipase A2 | chr1 | GO:1901981 | Not Cancer Driver | No | 149 | 0.199 | 129 | 28 | 0.217 | 1 |
| PLA2G4E | PLA2G4E | Q3MJ16 | Cytosolic phospholipase A2 epsilon | chr15 | GO:1901981 | Not Cancer Driver | No | 71 | 0.082 | 123 | 6 | 0.049 | 0 |
| PLCZ1 | PLCZ1 | Q86YW0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 | chr12 | GO:1901981 | Not Cancer Driver | No | 151 | 0.248 | 37 | 20 | 0.541 | 1 |
| PLEK2 | PLEK2 | Q9NYT0 | Pleckstrin-2 | chr14 | GO:1901981 | Not Cancer Driver | No | 41 | 0.116 | 25 | 5 | 0.2 | 0 |
| PLEKHA3 | PLEKHA3 | Q9HB20 | Pleckstrin homology domain-containing family A member 3 | chr2 | GO:1901981 | Not Cancer Driver | No | 30 | 0.1 | 159 | 19 | 0.119 | 0 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | GO:1901981 | Not Cancer Driver | No | 136 | 0.175 | 687 | 128 | 0.186 | 0 |
| PLEKHA5_ENST00000299275 | PLEKHA5 | Q9HAU0 | Pleckstrin homology domain-containing family A member 5 | chr12 | GO:1901981 | Not Cancer Driver | No | 144 | 0.129 | 869 | 114 | 0.131 | 0 |
| PLEKHA8 | PLEKHA8 | Q96JA3 | Pleckstrin homology domain-containing family A member 8 | chr7 | GO:1901981 | Not Cancer Driver | No | 57 | 0.11 | 128 | 22 | 0.172 | 0 |
| PLEKHB2_ENST00000409279 | PLEKHB2 | Q96CS7 | Pleckstrin homology domain-containing family B member 2 | chr2 | GO:1901981 | Not Cancer Driver | No | 40 | 0.18 | 42 | 11 | 0.262 | 0 |
| PLEKHF1 | PLEKHF1 | Q96S99 | Pleckstrin homology domain-containing family F member 1 | chr19 | GO:1901981 | Not Cancer Driver | No | 30 | 0.108 | 65 | 10 | 0.154 | 0 |
| PLEKHN1 | PLEKHN1 | Q494U1 | Pleckstrin homology domain-containing family N member 1 | chr1 | GO:1901981 | Not Cancer Driver | No | 59 | 0.097 | 369 | 37 | 0.1 | 0 |
| RACGAP1_ENST00000454520 | RACGAP1 | Q9H0H5 | Rac GTPase-activating protein 1 | chr12 | GO:1901981 | Not Cancer Driver | No | 74 | 0.117 | 255 | 27 | 0.106 | 0 |
| RAG2 | RAG2 | P55895 | V(D)J recombination-activating protein 2 | chr11 | GO:1901981 | Not Cancer Driver | No | 118 | 0.224 | 85 | 23 | 0.271 | 6 |
| RNF34_ENST00000361234 | RNF34 | Q969K3 | E3 ubiquitin-protein ligase RNF34 | chr12 | GO:1901981 | Not Cancer Driver | No | 30 | 0.081 | 112 | 7 | 0.062 | 0 |
| RPH3A | RPH3A | Q9Y2J0 | Rabphilin-3A | chr12 | GO:1901981 | Not Cancer Driver | No | 155 | 0.223 | 427 | 105 | 0.246 | 0 |
| RUBCN | RUBCN | Q92622 | Run domain Beclin-1-interacting and cysteine-rich domain-containing protein | chr3 | GO:1901981 | Not Cancer Driver | No | 147 | 0.151 | 403 | 57 | 0.141 | 0 |
| RUBCNL_ENST00000389908 | RUBCNL | Q9H714 | Protein associated with UVRAG as autophagy enhancer | chr13 | GO:1901981 | Not Cancer Driver | No | 92 | 0.139 | 219 | 32 | 0.146 | 0 |
| SAP30L | SAP30L | Q9HAJ7 | Histone deacetylase complex subunit SAP30L | chr5 | GO:1901981 | Not Cancer Driver | No | 18 | 0.098 | 111 | 14 | 0.126 | 0 |
| SESTD1 | SESTD1 | Q86VW0 | SEC14 domain and spectrin repeat-containing protein 1 | chr2 | GO:1901981 | Not Cancer Driver | No | 100 | 0.144 | 126 | 18 | 0.143 | 0 |
| SH3PXD2A_ENST00000369774 | SH3PXD2A | Q5TCZ1 | SH3 and PX domain-containing protein 2A | chr10 | GO:1901981 | Not Cancer Driver | No | 141 | 0.124 | 797 | 101 | 0.127 | 0 |
| SH3PXD2B | SH3PXD2B | A1X283 | SH3 and PX domain-containing protein 2B | chr5 | GO:1901981 | Not Cancer Driver | No | 122 | 0.134 | 660 | 101 | 0.153 | 1 |
| SNX11_ENST00000359238 | SNX11 | Q9Y5W9 | Sorting nexin-11 | chr17 | GO:1901981 | Not Cancer Driver | No | 30 | 0.111 | 112 | 8 | 0.071 | 0 |
| SNX14 | SNX14 | Q9Y5W7 | Sorting nexin-14 | chr6 | GO:1901981 | Not Cancer Driver | No | 94 | 0.099 | 99 | 12 | 0.121 | 0 |
| SNX20 | SNX20 | Q7Z614 | Sorting nexin-20 | chr16 | GO:1901981 | Not Cancer Driver | No | 56 | 0.177 | 72 | 12 | 0.167 | 0 |
| SNX21 | SNX21 | Q969T3 | Sorting nexin-21 | chr20 | GO:1901981 | Not Cancer Driver | No | 29 | 0.078 | 174 | 14 | 0.08 | 0 |
| SNX22 | SNX22 | Q96L94 | Sorting nexin-22 | chr15 | GO:1901981 | Not Cancer Driver | No | 20 | 0.104 | 70 | 8 | 0.114 | 0 |
| SNX24 | SNX24 | Q9Y343 | Sorting nexin-24 | chr5 | GO:1901981 | Not Cancer Driver | No | 24 | 0.142 | 14 | 3 | 0.214 | 0 |
| SNX3 | SNX3 | O60493 | Sorting nexin-3 | chr6 | GO:1901981 | Not Cancer Driver | No | 21 | 0.13 | 37 | 4 | 0.108 | 0 |
| SNX5_ENST00000377759 | SNX5 | Q9Y5X3 | Sorting nexin-5 | chr20 | GO:1901981 | Not Cancer Driver | No | 33 | 0.082 | 91 | 13 | 0.143 | 0 |
| TPCN1_ENST00000335509 | TPCN1 | Q9ULQ1 | Two pore channel protein 1 | chr12 | GO:1901981 | Not Cancer Driver | No | 114 | 0.14 | 99 | 18 | 0.182 | 0 |
| TPCN2 | TPCN2 | Q8NHX9 | Two pore channel protein 2 | chr11 | GO:1901981 | Not Cancer Driver | No | 73 | 0.097 | 16 | 0 | 0.0 | 0 |
| VEPH1 | VEPH1 | Q14D04 | Ventricular zone-expressed PH domain-containing protein homolog 1 | chr3 | GO:1901981 | Not Cancer Driver | No | 136 | 0.163 | 186 | 34 | 0.183 | 0 |
| WASHC2A | WASHC2A | Q641Q2 | WASH complex subunit 2A | chr10 | GO:1901981 | Not Cancer Driver | No | 48 | 0.036 | 1222 | 42 | 0.034 | 0 |
| WASHC2C_ENST00000374362 | WASHC2C | Q9Y4E1 | WASH complex subunit 2C | chr10 | GO:1901981 | Not Cancer Driver | No | 90 | 0.068 | 1204 | 89 | 0.074 | 0 |
| WDR45B | WDR45B | Q5MNZ6 | WD repeat domain phosphoinositide-interacting protein 3 | chr17 | GO:1901981 | Not Cancer Driver | No | 48 | 0.14 | 8 | 1 | 0.125 | 0 |
| WDR45_ENST00000634944 | WDR45 | Q9Y484 | WD repeat domain phosphoinositide-interacting protein 4 | chrX | GO:1901981 | Compendium | Yes | 62 | 0.172 | 10 | 1 | 0.1 | 0 |
| WIPI1 | WIPI1 | Q5MNZ9 | WD repeat domain phosphoinositide-interacting protein 1 | chr17 | GO:1901981 | Not Cancer Driver | No | 45 | 0.101 | 113 | 9 | 0.08 | 0 |
| WIPI2 | WIPI2 | Q9Y4P8 | WD repeat domain phosphoinositide-interacting protein 2 | chr7 | GO:1901981 | Not Cancer Driver | No | 64 | 0.141 | 68 | 5 | 0.074 | 1 |
| ZFYVE1 | ZFYVE1 | Q9HBF4 | Zinc finger FYVE domain-containing protein 1 | chr14 | GO:1901981 | Not Cancer Driver | No | 97 | 0.125 | 122 | 16 | 0.131 | 0 |
| ZFYVE16 | ZFYVE16 | Q7Z3T8 | Zinc finger FYVE domain-containing protein 16 | chr5 | GO:1901981 | Not Cancer Driver | No | 155 | 0.101 | 651 | 65 | 0.1 | 0 |