Total number of protein in "GO:1901224" GO term: 66
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTN4 | ACTN4 | O43707 | Alpha-actinin-4 | chr19 | GO:1901224 | Not Cancer Driver | No | 131 | 0.144 | 244 | 42 | 0.172 | 8 |
| AGER_ENST00000375076 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:1901224 | Not Cancer Driver | No | 31 | 0.077 | 297 | 21 | 0.071 | 0 |
| AGO3 | AGO3 | Q9H9G7 | Protein argonaute-3 | chr1 | GO:1901224 | Not Cancer Driver | No | 110 | 0.128 | 143 | 19 | 0.133 | 0 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:1901224 | Not Cancer Driver | No | 128 | 0.166 | 418 | 71 | 0.17 | 17 |
| C1QTNF4 | C1QTNF4 | Q9BXJ3 | Complement C1q tumor necrosis factor-related protein 4 | chr11 | GO:1901224 | Not Cancer Driver | No | 25 | 0.076 | 91 | 4 | 0.044 | 0 |
| C20orf27_ENST00000379772 | C20orf27 | Q9GZN8 | UPF0687 protein C20orf27 | chr20 | GO:1901224 | Not Cancer Driver | No | 27 | 0.155 | 31 | 4 | 0.129 | 0 |
| CALR | CALR | P27797 | Calreticulin | chr19 | GO:1901224 | Census | Yes | 45 | 0.108 | 245 | 31 | 0.127 | 0 |
| CCL19 | CCL19 | Q99731 | C-C motif chemokine 19 | chr9 | GO:1901224 | Not Cancer Driver | No | 10 | 0.102 | 7 | 0 | 0.0 | 0 |
| CD14 | CD14 | P08571 | Monocyte differentiation antigen CD14 | chr5 | GO:1901224 | Not Cancer Driver | No | 42 | 0.112 | 60 | 5 | 0.083 | 0 |
| CD27 | CD27 | P26842 | CD27 antigen | chr12 | GO:1901224 | Not Cancer Driver | No | 30 | 0.115 | 92 | 11 | 0.12 | 1 |
| CD86 | CD86 | P42081 | T-lymphocyte activation antigen CD86 | chr3 | GO:1901224 | Not Cancer Driver | No | 90 | 0.274 | 56 | 18 | 0.321 | 0 |
| DDX3X_ENST00000629496 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:1901224 | Census, Compendium | Yes | 133 | 0.201 | 301 | 47 | 0.156 | 18 |
| EDA | EDA | Q92838 | Ectodysplasin-A | chrX | GO:1901224 | Not Cancer Driver | No | 73 | 0.187 | 243 | 43 | 0.177 | 71 |
| EDAR | EDAR | Q9UNE0 | Tumor necrosis factor receptor superfamily member EDAR | chr2 | GO:1901224 | Not Cancer Driver | No | 81 | 0.181 | 116 | 20 | 0.172 | 18 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:1901224 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:1901224 | Census, Compendium | Yes | 444 | 0.367 | 223 | 35 | 0.157 | 1 |
| EIF2AK2_ENST00000395127 | EIF2AK2 | P19525 | Interferon-induced, double-stranded RNA-activated protein kinase | chr2 | GO:1901224 | Not Cancer Driver | No | 59 | 0.107 | 188 | 22 | 0.117 | 0 |
| EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:1901224 | Census, Compendium | Yes | 334 | 0.138 | 1790 | 196 | 0.109 | 1 |
| GREM1 | GREM1 | O60565 | Gremlin-1 | chr15 | GO:1901224 | Not Cancer Driver | No | 25 | 0.136 | 77 | 12 | 0.156 | 0 |
| HAVCR2 | HAVCR2 | Q8TDQ0 | Hepatitis A virus cellular receptor 2 | chr5 | GO:1901224 | Not Cancer Driver | No | 69 | 0.229 | 17 | 2 | 0.118 | 3 |
| IFI35_ENST00000415816 | IFI35 | P80217 | Interferon-induced 35 kDa protein | chr17 | GO:1901224 | Not Cancer Driver | No | 33 | 0.115 | 63 | 10 | 0.159 | 0 |
| IL12B | IL12B | P29460 | Interleukin-12 subunit beta | chr5 | GO:1901224 | Not Cancer Driver | No | 48 | 0.146 | 42 | 2 | 0.048 | 0 |
| IL18 | IL18 | Q14116 | Interleukin-18 | chr11 | GO:1901224 | Not Cancer Driver | No | 19 | 0.098 | 16 | 3 | 0.188 | 0 |
| IL18R1_ENST00000233957 | IL18R1 | Q13478 | Interleukin-18 receptor 1 | chr2 | GO:1901224 | Not Cancer Driver | No | 104 | 0.192 | 18 | 3 | 0.167 | 0 |
| IL1B | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:1901224 | Not Cancer Driver | No | 39 | 0.145 | 16 | 3 | 0.188 | 0 |
| IL23A | IL23A | Q9NPF7 | Interleukin-23 subunit alpha | chr12 | GO:1901224 | Not Cancer Driver | No | 15 | 0.079 | 42 | 3 | 0.071 | 0 |
| ILK_ENST00000299421 | ILK | Q13418 | Integrin-linked protein kinase | chr11 | GO:1901224 | Not Cancer Driver | No | 45 | 0.1 | 71 | 9 | 0.127 | 0 |
| IRAK1 | IRAK1 | P51617 | Interleukin-1 receptor-associated kinase 1 | chrX | GO:1901224 | Compendium | Yes | 71 | 0.1 | 337 | 39 | 0.116 | 0 |
| LAPTM5 | LAPTM5 | Q13571 | Lysosomal-associated transmembrane protein 5 | chr1 | GO:1901224 | Not Cancer Driver | No | 46 | 0.176 | 16 | 6 | 0.375 | 0 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | GO:1901224 | Not Cancer Driver | No | 54 | 0.152 | 65 | 16 | 0.246 | 0 |
| LIMS1_ENST00000393310 | LIMS1 | P48059 | LIM and senescent cell antigen-like-containing domain protein 1 | chr2 | GO:1901224 | Not Cancer Driver | No | 34 | 0.105 | 0 | 0 | 0.0 | 0 |
| LRRC19 | LRRC19 | Q9H756 | Leucine-rich repeat-containing protein 19 | chr9 | GO:1901224 | Not Cancer Driver | No | 37 | 0.1 | 30 | 3 | 0.1 | 0 |
| MMP8 | MMP8 | P22894 | Neutrophil collagenase | chr11 | GO:1901224 | Not Cancer Driver | No | 73 | 0.156 | 115 | 19 | 0.165 | 0 |
| NFAT5_ENST00000354436 | NFAT5 | O94916 | Nuclear factor of activated T-cells 5 | chr16 | GO:1901224 | Not Cancer Driver | No | 142 | 0.093 | 1307 | 119 | 0.091 | 0 |
| NLRP12_ENST00000324134 | NLRP12 | P59046 | NACHT, LRR and PYD domains-containing protein 12 | chr19 | GO:1901224 | Not Cancer Driver | No | 310 | 0.292 | 116 | 43 | 0.371 | 0 |
| NMI | NMI | Q13287 | N-myc-interactor | chr2 | GO:1901224 | Not Cancer Driver | No | 34 | 0.111 | 104 | 12 | 0.115 | 0 |
| NOD1 | NOD1 | Q9Y239 | Nucleotide-binding oligomerization domain-containing protein 1 | chr7 | GO:1901224 | Not Cancer Driver | No | 130 | 0.136 | 38 | 7 | 0.184 | 0 |
| NOD2 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:1901224 | Not Cancer Driver | No | 169 | 0.163 | 40 | 4 | 0.1 | 15 |
| NR3C2_ENST00000344721 | NR3C2 | P08235 | Mineralocorticoid receptor | chr4 | GO:1901224 | Not Cancer Driver | No | 168 | 0.171 | 484 | 88 | 0.182 | 14 |
| PDCD4 | PDCD4 | Q53EL6 | Programmed cell death protein 4 | chr10 | GO:1901224 | Not Cancer Driver | No | 57 | 0.122 | 187 | 32 | 0.171 | 0 |
| PHB2 | PHB2 | Q99623 | Prohibitin-2 | chr12 | GO:1901224 | Not Cancer Driver | No | 31 | 0.104 | 26 | 4 | 0.154 | 0 |
| PHB_ENST00000300408 | PHB1 | P35232 | Prohibitin 1 | chr17 | GO:1901224 | Not Cancer Driver | No | 37 | 0.136 | 4 | 1 | 0.25 | 0 |
| PTP4A3_ENST00000521578 | PTP4A3 | O75365 | Protein tyrosine phosphatase type IVA 3 | chr8 | GO:1901224 | Not Cancer Driver | No | 30 | 0.173 | 3 | 0 | 0.0 | 0 |
| RBCK1 | RBCK1 | Q9BYM8 | RanBP-type and C3HC4-type zinc finger-containing protein 1 | chr20 | GO:1901224 | Not Cancer Driver | No | 52 | 0.102 | 140 | 14 | 0.1 | 2 |
| RC3H1_ENST00000258349 | RC3H1 | Q5TC82 | Roquin-1 | chr1 | GO:1901224 | Not Cancer Driver | No | 158 | 0.139 | 796 | 115 | 0.144 | 0 |
| RC3H2_ENST00000357244 | RC3H2 | Q9HBD1 | Roquin-2 | chr9 | GO:1901224 | Not Cancer Driver | No | 128 | 0.107 | 703 | 81 | 0.115 | 0 |
| RELA | RELA | Q04206 | Transcription factor p65 | chr11 | GO:1901224 | Compendium | Yes | 75 | 0.136 | 400 | 48 | 0.12 | 0 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:1901224 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
| RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:1901224 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
| RTKN2 | RTKN2 | Q8IZC4 | Rhotekin-2 | chr10 | GO:1901224 | Not Cancer Driver | No | 71 | 0.117 | 158 | 21 | 0.133 | 0 |
| SASH1 | SASH1 | O94885 | SAM and SH3 domain-containing protein 1 | chr6 | GO:1901224 | Not Cancer Driver | No | 174 | 0.14 | 1071 | 153 | 0.143 | 7 |
| SPHK1_ENST00000545180 | SPHK1 | Q9NYA1 | Sphingosine kinase 1 | chr17 | GO:1901224 | Not Cancer Driver | No | 47 | 0.122 | 25 | 2 | 0.08 | 0 |
| TCIM | TCIM | Q9NR00 | Transcriptional and immune response regulator | chr8 | GO:1901224 | Not Cancer Driver | No | 21 | 0.198 | 33 | 7 | 0.212 | 0 |
| TERF2IP | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | GO:1901224 | Not Cancer Driver | No | 28 | 0.07 | 310 | 16 | 0.052 | 0 |
| TLR2 | TLR2 | O60603 | Toll-like receptor 2 | chr4 | GO:1901224 | Not Cancer Driver | No | 108 | 0.138 | 0 | 0 | 0.0 | 0 |
| TLR3 | TLR3 | O15455 | Toll-like receptor 3 | chr4 | GO:1901224 | Not Cancer Driver | No | 123 | 0.136 | 0 | 0 | 0.0 | 1 |
| TLR4_ENST00000355622 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:1901224 | Not Cancer Driver | No | 292 | 0.348 | 0 | 0 | 0.0 | 0 |
| TLR7 | TLR7 | Q9NYK1 | Toll-like receptor 7 | chrX | GO:1901224 | Not Cancer Driver | No | 182 | 0.173 | 14 | 1 | 0.071 | 1 |
| TLR9 | TLR9 | Q9NR96 | Toll-like receptor 9 | chr3 | GO:1901224 | Not Cancer Driver | No | 141 | 0.137 | 35 | 3 | 0.086 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:1901224 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFSF14 | TNFSF14 | O43557 | Tumor necrosis factor ligand superfamily member 14 | chr19 | GO:1901224 | Not Cancer Driver | No | 58 | 0.242 | 18 | 1 | 0.056 | 0 |
| TRADD | TRADD | Q15628 | Tumor necrosis factor receptor type 1-associated DEATH domain protein | chr16 | GO:1901224 | Not Cancer Driver | No | 26 | 0.083 | 74 | 5 | 0.068 | 0 |
| TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:1901224 | Not Cancer Driver | No | 67 | 0.128 | 62 | 7 | 0.113 | 0 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:1901224 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |
| TRIM44 | TRIM44 | Q96DX7 | Tripartite motif-containing protein 44 | chr11 | GO:1901224 | Not Cancer Driver | No | 40 | 0.116 | 272 | 33 | 0.121 | 1 |
| TRIP6 | TRIP6 | Q15654 | Thyroid receptor-interacting protein 6 | chr7 | GO:1901224 | Not Cancer Driver | No | 62 | 0.13 | 268 | 19 | 0.071 | 0 |