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Total number of protein in "GO:1901215" GO term:  203

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AARS AARS1 P49588 Alanine--tRNA ligase, cytoplasmic chr16 GO:1901215 Not Cancer Driver No 97 0.1 140 14 0.1 5
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:1901215 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 GO:1901215 Not Cancer Driver No 130 0.118 615 66 0.107 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:1901215 Not Cancer Driver No 61 0.148 93 11 0.118 0
AGAP2 AGAP2 Q99490 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 chr12 GO:1901215 Not Cancer Driver No 133 0.112 754 81 0.107 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:1901215 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALKBH1 ALKBH1 Q13686 Nucleic acid dioxygenase ALKBH1 chr14 GO:1901215 Not Cancer Driver No 55 0.141 77 11 0.143 0
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:1901215 Not Cancer Driver No 130 0.261 131 24 0.183 1
AP2B1_ENST00000621914 AP2B1 P63010 AP-2 complex subunit beta chr17 GO:1901215 Not Cancer Driver No 85 0.091 95 12 0.126 0
APOE APOE P02649 Apolipoprotein E chr19 GO:1901215 Not Cancer Driver No 25 0.079 124 6 0.048 12
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:1901215 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:1901215 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATP13A2 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:1901215 Not Cancer Driver No 152 0.129 121 10 0.083 9
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:1901215 Not Cancer Driver No 168 0.188 341 64 0.188 0
BARHL1_ENST00000542090 BARHL1 Q9BZE3 BarH-like 1 homeobox protein chr9 GO:1901215 Not Cancer Driver No 43 0.131 240 30 0.125 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:1901215 Census Yes 30 0.156 39 2 0.051 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:1901215 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:1901215 Census, Compendium Yes 24 0.1 72 5 0.069 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:1901215 Not Cancer Driver No 47 0.19 79 19 0.241 1
BHLHB9 BHLHB9 Q6PI77 Protein BHLHb9 chrX GO:1901215 Not Cancer Driver No 88 0.161 267 38 0.142 0
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:1901215 Not Cancer Driver No 7 0.033 0 0 0.0 0
BTBD10_ENST00000278174 BTBD10 Q9BSF8 BTB/POZ domain-containing protein 10 chr11 GO:1901215 Not Cancer Driver No 59 0.124 252 31 0.123 0
BTG2 BTG2 P78543 Protein BTG2 chr1 GO:1901215 Census Yes 32 0.203 7 2 0.286 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:1901215 Census, Compendium Yes 115 0.127 512 56 0.109 4
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:1901215 Not Cancer Driver No 20 0.202 15 5 0.333 0
CD200R1_ENST00000471858 CD200R1 Q8TD46 Cell surface glycoprotein CD200 receptor 1 chr3 GO:1901215 Not Cancer Driver No 87 0.268 56 12 0.214 0
CD200_ENST00000315711 CD200 P41217 OX-2 membrane glycoprotein chr3 GO:1901215 Not Cancer Driver No 37 0.133 14 0 0.0 0
CD34 CD34 P28906 Hematopoietic progenitor cell antigen CD34 chr1 GO:1901215 Not Cancer Driver No 65 0.169 221 34 0.154 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:1901215 Not Cancer Driver No 48 0.164 5 1 0.2 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:1901215 Not Cancer Driver No 3 0.009 276 2 0.007 0
CHGA CHGA P10645 Chromogranin-A chr14 GO:1901215 Not Cancer Driver No 46 0.101 421 44 0.105 0
CHL1_ENST00000397491 CHL1 O00533 Neural cell adhesion molecule L1-like protein chr3 GO:1901215 Not Cancer Driver No 348 0.288 415 121 0.292 0
CHMP4A_ENST00000609024 CHMP4A Q9BY43 Charged multivesicular body protein 4a chr14 GO:1901215 Not Cancer Driver No 24 0.108 204 23 0.113 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 GO:1901215 Not Cancer Driver No 25 0.112 201 22 0.109 2
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:1901215 Not Cancer Driver No 24 0.124 166 21 0.127 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:1901215 Not Cancer Driver No 22 0.098 42 4 0.095 1
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 GO:1901215 Not Cancer Driver No 58 0.132 69 10 0.145 9
CNTF CNTF P26441 Ciliary neurotrophic factor chr11 GO:1901215 Not Cancer Driver No 41 0.205 34 5 0.147 0
CNTFR_ENST00000351266 CNTFR P26992 Ciliary neurotrophic factor receptor subunit alpha chr9 GO:1901215 Not Cancer Driver No 50 0.134 92 8 0.087 0
CORO1A CORO1A P31146 Coronin-1A chr16 GO:1901215 Not Cancer Driver No 51 0.111 126 15 0.119 1
CPEB4 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 GO:1901215 Not Cancer Driver No 85 0.117 443 54 0.122 0
CRLF1 CRLF1 O75462 Cytokine receptor-like factor 1 chr19 GO:1901215 Not Cancer Driver No 51 0.121 101 7 0.069 14
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:1901215 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:1901215 Not Cancer Driver No 20 0.097 7 0 0.0 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:1901215 Census, Compendium Yes 415 0.531 288 301 1.045 14
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:1901215 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:1901215 Not Cancer Driver No 80 0.225 0 0 0.0 0
DLX1 DLX1 P56177 Homeobox protein DLX-1 chr2 GO:1901215 Not Cancer Driver No 25 0.098 183 21 0.115 0
DNAJC5 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 GO:1901215 Not Cancer Driver No 23 0.116 46 6 0.13 1
DRAXIN DRAXIN Q8NBI3 Draxin chr1 GO:1901215 Not Cancer Driver No 61 0.175 249 48 0.193 0
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 GO:1901215 Not Cancer Driver No 49 0.14 210 25 0.119 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:1901215 Not Cancer Driver No 229 0.143 1079 153 0.142 2
EN1 EN1 Q05925 Homeobox protein engrailed-1 chr2 GO:1901215 Not Cancer Driver No 42 0.107 357 30 0.084 0
EN2 EN2 P19622 Homeobox protein engrailed-2 chr7 GO:1901215 Not Cancer Driver No 23 0.069 317 23 0.073 0
ENO2 ENO2 P09104 Gamma-enolase chr12 GO:1901215 Not Cancer Driver No 48 0.111 12 2 0.167 0
EPO EPO P01588 Erythropoietin chr7 GO:1901215 Not Cancer Driver No 27 0.14 9 1 0.111 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:1901215 Census, Compendium Yes 298 0.222 396 70 0.177 3
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:1901215 Not Cancer Driver No 73 0.172 19 2 0.105 0
FAIM2 FAIM2 Q9BWQ8 Protein lifeguard 2 chr12 GO:1901215 Not Cancer Driver No 37 0.117 54 11 0.204 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:1901215 Not Cancer Driver No 75 0.144 243 38 0.156 1
FGF20 FGF20 Q9NP95 Fibroblast growth factor 20 chr8 GO:1901215 Not Cancer Driver No 25 0.118 57 3 0.053 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:1901215 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:1901215 Not Cancer Driver No 30 0.129 79 9 0.114 6
FOXB1 FOXB1 Q99853 Forkhead box protein B1 chr15 GO:1901215 Not Cancer Driver No 31 0.095 114 5 0.044 0
FOXQ1 FOXQ1 Q9C009 Forkhead box protein Q1 chr6 GO:1901215 Not Cancer Driver No 22 0.055 245 4 0.016 0
FZD1 FZD1 Q9UP38 Frizzled-1 chr7 GO:1901215 Not Cancer Driver No 78 0.121 133 2 0.015 0
FZD9 FZD9 O00144 Frizzled-9 chr7 GO:1901215 Not Cancer Driver No 55 0.093 61 0 0.0 0
GABRA5_ENST00000355395 GABRA5 P31644 Gamma-aminobutyric acid receptor subunit alpha-5 chr15 GO:1901215 Not Cancer Driver No 146 0.316 55 14 0.255 3
GABRB2_ENST00000393959 GABRB2 P47870 Gamma-aminobutyric acid receptor subunit beta-2 chr5 GO:1901215 Not Cancer Driver No 165 0.322 27 10 0.37 1
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:1901215 Not Cancer Driver No 74 0.138 38 5 0.132 171
GBE1 GBE1 Q04446 1,4-alpha-glucan-branching enzyme chr3 GO:1901215 Not Cancer Driver No 101 0.144 8 0 0.0 9
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:1901215 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:1901215 Not Cancer Driver No 32 0.117 31 3 0.097 0
GDF5_ENST00000374369 GDF5 P43026 Growth/differentiation factor 5 chr20 GO:1901215 Not Cancer Driver No 104 0.208 255 50 0.196 24
GDNF_ENST00000326524 GDNF P39905 Glial cell line-derived neurotrophic factor chr5 GO:1901215 Not Cancer Driver No 47 0.223 83 18 0.217 2
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:1901215 Not Cancer Driver No 10 0.049 97 4 0.041 1
GFRAL GFRAL Q6UXV0 GDNF family receptor alpha-like chr6 GO:1901215 Not Cancer Driver No 176 0.447 5 2 0.4 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:1901215 Not Cancer Driver No 173 0.271 229 66 0.288 19
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 GO:1901215 Not Cancer Driver No 77 0.138 73 11 0.151 24
GPNMB GPNMB Q14956 Transmembrane glycoprotein NMB chr7 GO:1901215 Not Cancer Driver No 89 0.156 94 18 0.191 0
GRIK2 GRIK2 Q13002 Glutamate receptor ionotropic, kainate 2 chr6 GO:1901215 Not Cancer Driver No 284 0.313 57 19 0.333 0
GRN GRN P28799 Progranulin chr17 GO:1901215 Not Cancer Driver No 76 0.128 29 6 0.207 1
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:1901215 Not Cancer Driver No 56 0.133 146 13 0.089 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 GO:1901215 Not Cancer Driver No 35 0.146 203 29 0.143 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:1901215 Census Yes 118 0.143 435 51 0.117 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:1901215 Not Cancer Driver No 154 0.129 686 96 0.14 0
HLA-F_ENST00000376861 HLA-F P30511 HLA class I histocompatibility antigen, alpha chain F chr6 GO:1901215 Not Cancer Driver No 43 0.124 115 22 0.191 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:1901215 Not Cancer Driver No 46 0.16 81 13 0.16 0
HRAS HRAS P01112 GTPase HRas chr11 GO:1901215 Census, Compendium Yes 107 0.566 16 4 0.25 18
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:1901215 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:1901215 Census, Compendium Yes 100 0.138 254 43 0.169 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:1901215 Compendium Yes 44 0.096 127 9 0.071 2
HYOU1 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 GO:1901215 Not Cancer Driver No 132 0.132 373 47 0.126 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX GO:1901215 Not Cancer Driver No 6 0.014 301 6 0.02 22
IL10 IL10 P22301 Interleukin-10 chr1 GO:1901215 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL13 IL13 P35225 Interleukin-13 chr5 GO:1901215 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:1901215 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 GO:1901215 Census, Compendium Yes 102 0.111 315 40 0.127 2
INPP5A INPP5A Q14642 Inositol polyphosphate-5-phosphatase A chr10 GO:1901215 Not Cancer Driver No 59 0.143 7 4 0.571 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:1901215 Not Cancer Driver No 85 0.244 180 41 0.228 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:1901215 Census, Compendium Yes 136 0.12 59 5 0.085 5
JUN JUN P05412 Transcription factor Jun chr1 GO:1901215 Census Yes 35 0.106 281 25 0.089 0
KDM2B KDM2B Q8NHM5 Lysine-specific demethylase 2B chr12 GO:1901215 Not Cancer Driver No 187 0.14 617 90 0.146 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 GO:1901215 Not Cancer Driver No 222 0.135 774 102 0.132 2
KIR3DL2 KIR3DL2 P43630 Killer cell immunoglobulin-like receptor 3DL2 chr19 GO:1901215 Not Cancer Driver No 91 0.2 118 31 0.263 0
KRAS KRAS P01116 GTPase KRas chr12 GO:1901215 Census, Compendium Yes 788 4.169 7 2 0.286 27
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:1901215 Not Cancer Driver No 57 0.132 112 19 0.17 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:1901215 Not Cancer Driver No 134 0.147 63 10 0.159 2
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:1901215 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAG_ENST00000537831 MAG P20916 Myelin-associated glycoprotein chr19 GO:1901215 Not Cancer Driver No 118 0.188 65 7 0.108 1
MAP2K4_ENST00000353533 MAP2K4 P45985 Dual specificity mitogen-activated protein kinase kinase 4 chr17 GO:1901215 Census, Compendium Yes 89 0.223 137 28 0.204 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:1901215 Not Cancer Driver No 120 0.14 481 64 0.133 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:1901215 Not Cancer Driver No 15 0.105 20 2 0.1 0
MEAK7 MEAK7 Q6P9B6 MTOR-associated protein MEAK7 chr16 GO:1901215 Not Cancer Driver No 56 0.123 182 24 0.132 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:1901215 Not Cancer Driver No 75 0.154 483 74 0.153 46
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:1901215 Not Cancer Driver No 92 0.195 408 81 0.199 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:1901215 Census Yes 92 0.099 37 4 0.108 70
MT3 MT3 P25713 Metallothionein-3 chr16 GO:1901215 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 GO:1901215 Not Cancer Driver No 104 0.287 8 1 0.125 0
NAIP_ENST00000194097 NAIP Q13075 Baculoviral IAP repeat-containing protein 1 chr5 GO:1901215 Not Cancer Driver No 39 0.028 67 4 0.06 0
NCOA7_ENST00000368357 NCOA7 Q8NI08 Nuclear receptor coactivator 7 chr6 GO:1901215 Not Cancer Driver No 110 0.117 538 63 0.117 0
NDNF NDNF Q8TB73 Protein NDNF chr4 GO:1901215 Not Cancer Driver No 125 0.22 129 29 0.225 1
NEFL NEFL P07196 Neurofilament light polypeptide chr8 GO:1901215 Not Cancer Driver No 92 0.169 285 39 0.137 12
NENF NENF Q9UMX5 Neudesin chr1 GO:1901215 Not Cancer Driver No 15 0.087 98 7 0.071 0
NES NES P48681 Nestin chr1 GO:1901215 Not Cancer Driver No 271 0.167 1474 253 0.172 0
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:1901215 Not Cancer Driver No 155 0.172 685 120 0.175 0
NGF NGF P01138 Beta-nerve growth factor chr1 GO:1901215 Not Cancer Driver No 66 0.274 93 25 0.269 1
NMNAT1 NMNAT1 Q9HAN9 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 chr1 GO:1901215 Not Cancer Driver No 39 0.14 49 7 0.143 28
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX GO:1901215 Census, Compendium Yes 101 0.214 349 64 0.183 0
NPY_ENST00000405982 NPY P01303 Pro-neuropeptide Y chr7 GO:1901215 Not Cancer Driver No 29 0.299 43 19 0.442 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:1901215 Not Cancer Driver No 110 0.184 261 38 0.146 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:1901215 Census Yes 83 0.133 298 37 0.124 0
NRBP2 NRBP2 Q9NSY0 Nuclear receptor-binding protein 2 chr8 GO:1901215 Not Cancer Driver No 30 0.06 110 5 0.045 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:1901215 Compendium Yes 146 0.158 211 31 0.147 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:1901215 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTF4 NTF4 P34130 Neurotrophin-4 chr19 GO:1901215 Not Cancer Driver No 21 0.1 56 4 0.071 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:1901215 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:1901215 Not Cancer Driver No 155 0.189 117 18 0.154 1
OXR1 OXR1 Q8N573 Oxidation resistance protein 1 chr8 GO:1901215 Not Cancer Driver No 126 0.144 544 76 0.14 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:1901215 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP2 PARP2 Q9UGN5 Poly [ADP-ribose] polymerase 2 chr14 GO:1901215 Not Cancer Driver No 74 0.127 172 23 0.134 0
PCDHGC3 PCDHGC3 Q9UN70 Protocadherin gamma-C3 chr5 GO:1901215 Not Cancer Driver No 113 0.121 367 34 0.093 0
PCDHGC4 PCDHGC4 Q9Y5F7 Protocadherin gamma-C4 chr5 GO:1901215 Not Cancer Driver No 136 0.145 460 59 0.128 0
PCDHGC5 PCDHGC5 Q9Y5F6 Protocadherin gamma-C5 chr5 GO:1901215 Not Cancer Driver No 135 0.143 492 72 0.146 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:1901215 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:1901215 Not Cancer Driver No 57 0.098 99 13 0.131 23
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:1901215 Not Cancer Driver No 115 0.226 175 39 0.223 0
PM20D1 PM20D1 Q6GTS8 N-fatty-acyl-amino acid synthase/hydrolase PM20D1 chr1 GO:1901215 Not Cancer Driver No 79 0.157 42 10 0.238 0
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:1901215 Not Cancer Driver No 51 0.122 273 34 0.125 1
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:1901215 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:1901215 Not Cancer Driver No 181 0.227 609 148 0.243 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:1901215 Not Cancer Driver No 37 0.121 0 0 0.0 23
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:1901215 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKCI PRKCI P41743 Protein kinase C iota type chr3 GO:1901215 Not Cancer Driver No 110 0.185 120 16 0.133 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:1901215 Not Cancer Driver No 110 0.237 78 15 0.192 31
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:1901215 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSMC1 PSMC1 P62191 26S proteasome regulatory subunit 4 chr14 GO:1901215 Not Cancer Driver No 36 0.082 165 10 0.061 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:1901215 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPRZ1 PTPRZ1 P23471 Receptor-type tyrosine-protein phosphatase zeta chr7 GO:1901215 Not Cancer Driver No 480 0.207 978 216 0.221 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:1901215 Not Cancer Driver No 34 0.107 13 0 0.0 0
RASA1 RASA1 P20936 Ras GTPase-activating protein 1 chr5 GO:1901215 Compendium Yes 154 0.147 181 25 0.138 3
REST REST Q13127 RE1-silencing transcription factor chr4 GO:1901215 Not Cancer Driver No 142 0.129 868 113 0.13 4
RETREG1 RETREG1 Q9H6L5 Reticulophagy regulator 1 chr5 GO:1901215 Not Cancer Driver No 48 0.097 245 21 0.086 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:1901215 Census, Compendium Yes 99 0.513 46 13 0.283 2
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:1901215 Not Cancer Driver No 184 0.136 780 103 0.132 0
SERPINF1 SERPINF1 P36955 Pigment epithelium-derived factor chr17 GO:1901215 Not Cancer Driver No 51 0.122 57 5 0.088 0
SET SET Q01105 Protein SET chr9 GO:1901215 Census, Compendium Yes 35 0.121 221 26 0.118 2
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:1901215 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:1901215 Census, Compendium Yes 49 0.173 144 25 0.174 8
SIX4 SIX4 Q9UIU6 Homeobox protein SIX4 chr14 GO:1901215 Not Cancer Driver No 99 0.127 460 58 0.126 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:1901215 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC23A2 SLC23A2 Q9UGH3 Solute carrier family 23 member 2 chr20 GO:1901215 Not Cancer Driver No 87 0.134 76 8 0.105 0
SLC30A10 SLC30A10 Q6XR72 Zinc transporter 10 chr1 GO:1901215 Not Cancer Driver No 68 0.14 61 10 0.164 2
SLC7A11 SLC7A11 Q9UPY5 Cystine/glutamate transporter chr4 GO:1901215 Not Cancer Driver No 70 0.14 15 2 0.133 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:1901215 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNCB_ENST00000510387 SNCB Q16143 Beta-synuclein chr5 GO:1901215 Not Cancer Driver No 23 0.172 110 21 0.191 0
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 GO:1901215 Not Cancer Driver No 33 0.081 85 7 0.082 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:1901215 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:1901215 Not Cancer Driver No 32 0.144 25 5 0.2 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:1901215 Not Cancer Driver No 374 0.169 87 10 0.115 0
STAMBP_ENST00000339566 STAMBP O95630 STAM-binding protein chr2 GO:1901215 Not Cancer Driver No 51 0.12 139 16 0.115 6
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:1901215 Not Cancer Driver No 97 0.163 111 23 0.207 18
SYNGAP1_ENST00000646630 SYNGAP1 Q96PV0 Ras/Rap GTPase-activating protein SynGAP chr6 GO:1901215 Not Cancer Driver No 153 0.114 830 90 0.108 2
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:1901215 Census Yes 110 0.097 212 16 0.075 31
TFAP2B TFAP2B Q92481 Transcription factor AP-2-beta chr6 GO:1901215 Not Cancer Driver No 114 0.248 306 75 0.245 6
TFAP2D TFAP2D Q7Z6R9 Transcription factor AP-2-delta chr6 GO:1901215 Not Cancer Driver No 164 0.363 161 54 0.335 0
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:1901215 Not Cancer Driver No 45 0.109 96 14 0.146 1
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:1901215 Not Cancer Driver No 44 0.163 39 9 0.231 0
TMEM259 TMEM259 Q4ZIN3 Membralin chr19 GO:1901215 Not Cancer Driver No 40 0.065 188 9 0.048 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:1901215 Not Cancer Driver No 48 0.104 229 28 0.122 0
TOX3 TOX3 O15405 TOX high mobility group box family member 3 chr16 GO:1901215 Not Cancer Driver No 85 0.148 485 72 0.148 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:1901215 Not Cancer Driver No 63 0.126 4 1 0.25 0
TSC1 TSC1 Q92574 Hamartin chr9 GO:1901215 Census, Compendium Yes 135 0.116 732 78 0.107 11
TYRO3 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:1901215 Not Cancer Driver No 119 0.134 197 17 0.086 0
UCN UCN P55089 Urocortin chr2 GO:1901215 Not Cancer Driver No 7 0.056 61 4 0.066 0
UNC5B UNC5B Q8IZJ1 Netrin receptor UNC5B chr10 GO:1901215 Not Cancer Driver No 155 0.164 117 20 0.171 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:1901215 Not Cancer Driver No 68 0.085 99 9 0.091 1
VSTM2L VSTM2L Q96N03 V-set and transmembrane domain-containing protein 2-like protein chr20 GO:1901215 Not Cancer Driver No 28 0.137 134 19 0.142 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:1901215 Not Cancer Driver No 105 0.118 203 10 0.049 39
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:1901215 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:1901215 Not Cancer Driver No 77 0.219 37 5 0.135 0
XRCC2 XRCC2 O43543 DNA repair protein XRCC2 chr7 GO:1901215 Not Cancer Driver No 36 0.129 9 1 0.111 2
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:1901215 Not Cancer Driver No 38 0.083 291 27 0.093 0