Total number of protein in "GO:0140097" GO term: 148
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALKBH1 | ALKBH1 | Q13686 | Nucleic acid dioxygenase ALKBH1 | chr14 | GO:0140097 | Not Cancer Driver | No | 55 | 0.141 | 77 | 11 | 0.143 | 0 |
| ALKBH2_ENST00000343075 | ALKBH2 | Q6NS38 | DNA oxidative demethylase ALKBH2 | chr12 | GO:0140097 | Not Cancer Driver | No | 34 | 0.13 | 73 | 14 | 0.192 | 0 |
| ALKBH4 | ALKBH4 | Q9NXW9 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 | chr7 | GO:0140097 | Not Cancer Driver | No | 39 | 0.129 | 14 | 2 | 0.143 | 0 |
| APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0140097 | Not Cancer Driver | No | 34 | 0.107 | 103 | 14 | 0.136 | 0 |
| APEX2 | APEX2 | Q9UBZ4 | DNA-(apurinic or apyrimidinic site) endonuclease 2 | chrX | GO:0140097 | Not Cancer Driver | No | 66 | 0.127 | 148 | 14 | 0.095 | 0 |
| APLF | APLF | Q8IW19 | Aprataxin and PNK-like factor | chr2 | GO:0140097 | Not Cancer Driver | No | 64 | 0.125 | 407 | 57 | 0.14 | 0 |
| APTX_ENST00000379819 | APTX | Q7Z2E3 | Aprataxin | chr9 | GO:0140097 | Not Cancer Driver | No | 36 | 0.101 | 101 | 6 | 0.059 | 9 |
| ATAD5 | ATAD5 | Q96QE3 | ATPase family AAA domain-containing protein 5 | chr17 | GO:0140097 | Not Cancer Driver | No | 200 | 0.108 | 1075 | 112 | 0.104 | 0 |
| ATRX | ATRX | P46100 | Transcriptional regulator ATRX | chrX | GO:0140097 | Census, Compendium | Yes | 487 | 0.195 | 1672 | 301 | 0.18 | 33 |
| BLM | BLM | P54132 | Bloom syndrome protein | chr15 | GO:0140097 | Census | Yes | 153 | 0.108 | 667 | 70 | 0.105 | 8 |
| BRIP1 | BRIP1 | Q9BX63 | Fanconi anemia group J protein | chr17 | GO:0140097 | Census | Yes | 174 | 0.139 | 397 | 59 | 0.149 | 6 |
| CECR2_ENST00000342247 | CECR2 | Q9BXF3 | Cat eye syndrome critical region protein 2 | chr22 | GO:0140097 | Not Cancer Driver | No | 222 | 0.15 | 1192 | 183 | 0.154 | 0 |
| CHD1 | CHD1 | O14646 | Chromodomain-helicase-DNA-binding protein 1 | chr5 | GO:0140097 | Not Cancer Driver | No | 172 | 0.101 | 975 | 109 | 0.112 | 4 |
| CHD2 | CHD2 | O14647 | Chromodomain-helicase-DNA-binding protein 2 | chr15 | GO:0140097 | Census, Compendium | Yes | 222 | 0.121 | 1051 | 136 | 0.129 | 2 |
| CHD3_ENST00000330494 | CHD3 | Q12873 | Chromodomain-helicase-DNA-binding protein 3 | chr17 | GO:0140097 | Not Cancer Driver | No | 235 | 0.117 | 1015 | 122 | 0.12 | 18 |
| CHD4 | CHD4 | Q14839 | Chromodomain-helicase-DNA-binding protein 4 | chr12 | GO:0140097 | Census, Compendium | Yes | 419 | 0.219 | 974 | 177 | 0.182 | 6 |
| CHD5 | CHD5 | Q8TDI0 | Chromodomain-helicase-DNA-binding protein 5 | chr1 | GO:0140097 | Not Cancer Driver | No | 365 | 0.187 | 931 | 183 | 0.197 | 0 |
| CHD6 | CHD6 | Q8TD26 | Chromodomain-helicase-DNA-binding protein 6 | chr20 | GO:0140097 | Not Cancer Driver | No | 393 | 0.145 | 1469 | 213 | 0.145 | 0 |
| CHD7 | CHD7 | Q9P2D1 | Chromodomain-helicase-DNA-binding protein 7 | chr8 | GO:0140097 | Not Cancer Driver | No | 464 | 0.155 | 1872 | 299 | 0.16 | 50 |
| CHD8_ENST00000643469 | CHD8 | Q9HCK8 | Chromodomain-helicase-DNA-binding protein 8 | chr14 | GO:0140097 | Not Cancer Driver | No | 328 | 0.127 | 1411 | 148 | 0.105 | 0 |
| CHTF18 | CHTF18 | Q8WVB6 | Chromosome transmission fidelity protein 18 homolog | chr16 | GO:0140097 | Not Cancer Driver | No | 114 | 0.117 | 503 | 56 | 0.111 | 0 |
| CHTF8_ENST00000398235 | CHTF8 | P0CG13 | Chromosome transmission fidelity protein 8 homolog | chr16 | GO:0140097 | Not Cancer Driver | No | 13 | 0.107 | 7 | 0 | 0.0 | 0 |
| CRY1 | CRY1 | Q16526 | Cryptochrome-1 | chr12 | GO:0140097 | Not Cancer Driver | No | 76 | 0.13 | 91 | 5 | 0.055 | 0 |
| CRY2_ENST00000616080 | CRY2 | Q49AN0 | Cryptochrome-2 | chr11 | GO:0140097 | Not Cancer Driver | No | 72 | 0.121 | 100 | 12 | 0.12 | 0 |
| DCLRE1A | DCLRE1A | Q6PJP8 | DNA cross-link repair 1A protein | chr10 | GO:0140097 | Not Cancer Driver | No | 92 | 0.088 | 514 | 45 | 0.088 | 0 |
| DCLRE1B | DCLRE1B | Q9H816 | 5' exonuclease Apollo | chr1 | GO:0140097 | Not Cancer Driver | No | 65 | 0.122 | 127 | 17 | 0.134 | 0 |
| DCLRE1C | DCLRE1C | Q96SD1 | Protein artemis | chr10 | GO:0140097 | Not Cancer Driver | No | 76 | 0.11 | 277 | 26 | 0.094 | 3 |
| DDX1 | DDX1 | Q92499 | ATP-dependent RNA helicase DDX1 | chr2 | GO:0140097 | Not Cancer Driver | No | 82 | 0.111 | 91 | 15 | 0.165 | 0 |
| DDX11 | DDX11 | Q96FC9 | ATP-dependent DNA helicase DDX11 | chr12 | GO:0140097 | Not Cancer Driver | No | 154 | 0.159 | 280 | 55 | 0.196 | 1 |
| DHX9 | DHX9 | Q08211 | ATP-dependent RNA helicase A | chr1 | GO:0140097 | Compendium | Yes | 182 | 0.143 | 331 | 42 | 0.127 | 0 |
| DICER1 | DICER1 | Q9UPY3 | Endoribonuclease Dicer | chr14 | GO:0140097 | Census, Compendium | Yes | 264 | 0.137 | 362 | 45 | 0.124 | 4 |
| DMC1 | DMC1 | Q14565 | Meiotic recombination protein DMC1/LIM15 homolog | chr22 | GO:0140097 | Not Cancer Driver | No | 39 | 0.115 | 49 | 5 | 0.102 | 0 |
| DNA2 | DNA2 | P51530 | DNA replication ATP-dependent helicase/nuclease DNA2 | chr10 | GO:0140097 | Not Cancer Driver | No | 120 | 0.113 | 52 | 8 | 0.154 | 3 |
| DNASE1L1 | DNASE1L1 | P49184 | Deoxyribonuclease-1-like 1 | chrX | GO:0140097 | Not Cancer Driver | No | 30 | 0.099 | 0 | 0 | 0.0 | 0 |
| DNASE1L2_ENST00000567494 | DNASE1L2 | Q92874 | Deoxyribonuclease-1-like 2 | chr16 | GO:0140097 | Not Cancer Driver | No | 23 | 0.077 | 15 | 1 | 0.067 | 0 |
| DNASE1L3 | DNASE1L3 | Q13609 | Deoxyribonuclease gamma | chr3 | GO:0140097 | Not Cancer Driver | No | 43 | 0.141 | 15 | 4 | 0.267 | 0 |
| DNASE1_ENST00000246949 | DNASE1 | P24855 | Deoxyribonuclease-1 | chr16 | GO:0140097 | Not Cancer Driver | No | 24 | 0.085 | 0 | 0 | 0.0 | 0 |
| DNASE2 | DNASE2 | O00115 | Deoxyribonuclease-2-alpha | chr19 | GO:0140097 | Not Cancer Driver | No | 46 | 0.128 | 48 | 7 | 0.146 | 0 |
| DNASE2B | DNASE2B | Q8WZ79 | Deoxyribonuclease-2-beta | chr1 | GO:0140097 | Not Cancer Driver | No | 53 | 0.147 | 14 | 1 | 0.071 | 0 |
| DNMT1_ENST00000340748 | DNMT1 | P26358 | DNA (cytosine-5)-methyltransferase 1 | chr19 | GO:0140097 | Not Cancer Driver | No | 203 | 0.126 | 702 | 78 | 0.111 | 4 |
| DNMT3A | DNMT3A | Q9Y6K1 | DNA (cytosine-5)-methyltransferase 3A | chr2 | GO:0140097 | Census, Compendium | Yes | 194 | 0.213 | 371 | 59 | 0.159 | 16 |
| DNMT3B | DNMT3B | Q9UBC3 | DNA (cytosine-5)-methyltransferase 3B | chr20 | GO:0140097 | Not Cancer Driver | No | 153 | 0.179 | 328 | 71 | 0.216 | 16 |
| DNTT | DNTT | P04053 | DNA nucleotidylexotransferase | chr10 | GO:0140097 | Not Cancer Driver | No | 106 | 0.208 | 66 | 16 | 0.242 | 0 |
| DSCC1 | DSCC1 | Q9BVC3 | Sister chromatid cohesion protein DCC1 | chr8 | GO:0140097 | Not Cancer Driver | No | 28 | 0.071 | 41 | 4 | 0.098 | 0 |
| ENDOG | ENDOG | Q14249 | Endonuclease G, mitochondrial | chr9 | GO:0140097 | Not Cancer Driver | No | 11 | 0.037 | 61 | 1 | 0.016 | 0 |
| ENDOV | ENDOV | Q8N8Q3 | Endonuclease V | chr17 | GO:0140097 | Not Cancer Driver | No | 28 | 0.099 | 43 | 3 | 0.07 | 0 |
| ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0140097 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
| ERCC2 | ERCC2 | P18074 | General transcription and DNA repair factor IIH helicase subunit XPD | chr19 | GO:0140097 | Census, Compendium | Yes | 150 | 0.197 | 5 | 0 | 0.0 | 35 |
| ERCC4 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:0140097 | Census | Yes | 120 | 0.131 | 225 | 27 | 0.12 | 15 |
| ERCC6 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | GO:0140097 | Not Cancer Driver | No | 211 | 0.141 | 829 | 117 | 0.141 | 9 |
| ERCC6L | ERCC6L | Q2NKX8 | DNA excision repair protein ERCC-6-like | chrX | GO:0140097 | Not Cancer Driver | No | 137 | 0.11 | 532 | 72 | 0.135 | 0 |
| EXD2 | EXD2 | Q9NVH0 | Exonuclease 3'-5' domain-containing protein 2 | chr14 | GO:0140097 | Not Cancer Driver | No | 58 | 0.093 | 176 | 15 | 0.085 | 0 |
| EXO1_ENST00000348581 | EXO1 | Q9UQ84 | Exonuclease 1 | chr1 | GO:0140097 | Not Cancer Driver | No | 123 | 0.145 | 472 | 76 | 0.161 | 0 |
| EXO5_ENST00000358527 | EXO5 | Q9H790 | Exonuclease V | chr1 | GO:0140097 | Not Cancer Driver | No | 39 | 0.105 | 36 | 3 | 0.083 | 0 |
| EXOG | EXOG | Q9Y2C4 | Nuclease EXOG, mitochondrial | chr3 | GO:0140097 | Not Cancer Driver | No | 42 | 0.114 | 52 | 1 | 0.019 | 0 |
| FAN1 | FAN1 | Q9Y2M0 | Fanconi-associated nuclease 1 | chr15 | GO:0140097 | Not Cancer Driver | No | 124 | 0.122 | 212 | 27 | 0.127 | 4 |
| FANCM | FANCM | Q8IYD8 | Fanconi anemia group M protein | chr14 | GO:0140097 | Not Cancer Driver | No | 268 | 0.131 | 898 | 128 | 0.143 | 0 |
| FBH1_ENST00000362091 | FBH1 | Q8NFZ0 | F-box DNA helicase 1 | chr10 | GO:0140097 | Not Cancer Driver | No | 139 | 0.133 | 192 | 32 | 0.167 | 0 |
| FEN1 | FEN1 | P39748 | Flap endonuclease 1 | chr11 | GO:0140097 | Census | Yes | 35 | 0.092 | 111 | 11 | 0.099 | 0 |
| FTO | FTO | Q9C0B1 | Alpha-ketoglutarate-dependent dioxygenase FTO | chr16 | GO:0140097 | Not Cancer Driver | No | 67 | 0.133 | 53 | 10 | 0.189 | 3 |
| G3BP1 | G3BP1 | Q13283 | Ras GTPase-activating protein-binding protein 1 | chr5 | GO:0140097 | Not Cancer Driver | No | 85 | 0.182 | 352 | 65 | 0.185 | 0 |
| GEN1_ENST00000381254 | GEN1 | Q17RS7 | Flap endonuclease GEN homolog 1 | chr2 | GO:0140097 | Not Cancer Driver | No | 109 | 0.12 | 339 | 52 | 0.153 | 0 |
| HELB | HELB | Q8NG08 | DNA helicase B | chr12 | GO:0140097 | Not Cancer Driver | No | 140 | 0.129 | 300 | 38 | 0.127 | 0 |
| HELQ | HELQ | Q8TDG4 | Helicase POLQ-like | chr4 | GO:0140097 | Not Cancer Driver | No | 134 | 0.122 | 273 | 19 | 0.07 | 0 |
| HMCES_ENST00000502878 | HMCES | Q96FZ2 | Abasic site processing protein HMCES | chr3 | GO:0140097 | Not Cancer Driver | No | 37 | 0.105 | 131 | 16 | 0.122 | 0 |
| HMGA2_ENST00000403681 | HMGA2 | P52926 | High mobility group protein HMGI-C | chr12 | GO:0140097 | Census | Yes | 12 | 0.11 | 109 | 12 | 0.11 | 0 |
| IGHMBP2 | IGHMBP2 | P38935 | DNA-binding protein SMUBP-2 | chr11 | GO:0140097 | Not Cancer Driver | No | 136 | 0.137 | 354 | 53 | 0.15 | 31 |
| ISG20 | ISG20 | Q96AZ6 | Interferon-stimulated gene 20 kDa protein | chr15 | GO:0140097 | Not Cancer Driver | No | 20 | 0.11 | 6 | 0 | 0.0 | 0 |
| LIG1 | LIG1 | P18858 | DNA ligase 1 | chr19 | GO:0140097 | Not Cancer Driver | No | 137 | 0.149 | 397 | 62 | 0.156 | 0 |
| LIG3 | LIG3 | P49916 | DNA ligase 3 | chr17 | GO:0140097 | Not Cancer Driver | No | 125 | 0.124 | 280 | 36 | 0.129 | 0 |
| LIG4 | LIG4 | P49917 | DNA ligase 4 | chr13 | GO:0140097 | Not Cancer Driver | No | 134 | 0.147 | 63 | 10 | 0.159 | 2 |
| MBD4 | MBD4 | O95243 | Methyl-CpG-binding domain protein 4 | chr3 | GO:0140097 | Not Cancer Driver | No | 61 | 0.105 | 268 | 27 | 0.101 | 0 |
| MCM6 | MCM6 | Q14566 | DNA replication licensing factor MCM6 | chr2 | GO:0140097 | Not Cancer Driver | No | 101 | 0.123 | 122 | 13 | 0.107 | 0 |
| MEIOB_ENST00000397344 | MEIOB | Q8N635 | Meiosis-specific with OB domain-containing protein | chr16 | GO:0140097 | Not Cancer Driver | No | 37 | 0.084 | 21 | 2 | 0.095 | 1 |
| METTL4 | METTL4 | Q8N3J2 | N(6)-adenine-specific methyltransferase METTL4 | chr18 | GO:0140097 | Not Cancer Driver | No | 61 | 0.129 | 34 | 4 | 0.118 | 0 |
| MGME1 | MGME1 | Q9BQP7 | Mitochondrial genome maintenance exonuclease 1 | chr20 | GO:0140097 | Not Cancer Driver | No | 33 | 0.096 | 95 | 7 | 0.074 | 1 |
| MPG | MPG | P29372 | DNA-3-methyladenine glycosylase | chr16 | GO:0140097 | Not Cancer Driver | No | 35 | 0.117 | 141 | 21 | 0.149 | 0 |
| MRE11 | MRE11 | P49959 | Double-strand break repair protein MRE11 | chr11 | GO:0140097 | Not Cancer Driver | No | 84 | 0.119 | 292 | 35 | 0.12 | 1 |
| MUS81 | MUS81 | Q96NY9 | Crossover junction endonuclease MUS81 | chr11 | GO:0140097 | Not Cancer Driver | No | 67 | 0.122 | 232 | 38 | 0.164 | 0 |
| MUTYH | MUTYH | Q9UIF7 | Adenine DNA glycosylase | chr1 | GO:0140097 | Census | Yes | 90 | 0.165 | 198 | 29 | 0.146 | 23 |
| N6AMT1 | N6AMT1 | Q9Y5N5 | Methyltransferase N6AMT1 | chr21 | GO:0140097 | Not Cancer Driver | No | 44 | 0.206 | 20 | 3 | 0.15 | 0 |
| NEIL1_ENST00000564784 | NEIL1 | Q96FI4 | Endonuclease 8-like 1 | chr15 | GO:0140097 | Not Cancer Driver | No | 41 | 0.105 | 165 | 14 | 0.085 | 0 |
| NEIL2 | NEIL2 | Q969S2 | Endonuclease 8-like 2 | chr8 | GO:0140097 | Not Cancer Driver | No | 31 | 0.093 | 145 | 14 | 0.097 | 0 |
| NEIL3 | NEIL3 | Q8TAT5 | Endonuclease 8-like 3 | chr4 | GO:0140097 | Not Cancer Driver | No | 80 | 0.132 | 131 | 18 | 0.137 | 0 |
| NTHL1 | NTHL1 | P78549 | Endonuclease III-like protein 1 | chr16 | GO:0140097 | Census | Yes | 38 | 0.122 | 147 | 18 | 0.122 | 0 |
| OGG1_ENST00000344629 | OGG1 | O15527 | N-glycosylase/DNA lyase | chr3 | GO:0140097 | Not Cancer Driver | No | 37 | 0.107 | 71 | 12 | 0.169 | 0 |
| PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | GO:0140097 | Not Cancer Driver | No | 30 | 0.115 | 22 | 3 | 0.136 | 1 |
| PGBD5 | PGBD5 | Q8N414 | PiggyBac transposable element-derived protein 5 | chr1 | GO:0140097 | Not Cancer Driver | No | 73 | 0.139 | 126 | 1 | 0.008 | 0 |
| PIF1_ENST00000559239 | PIF1 | Q9H611 | ATP-dependent DNA helicase PIF1 | chr15 | GO:0140097 | Not Cancer Driver | No | 54 | 0.084 | 209 | 11 | 0.053 | 0 |
| PLD3_ENST00000409735 | PLD3 | Q8IV08 | 5'-3' exonuclease PLD3 | chr19 | GO:0140097 | Not Cancer Driver | No | 70 | 0.143 | 62 | 7 | 0.113 | 0 |
| PLD4_ENST00000392593 | PLD4 | Q96BZ4 | 5'-3' exonuclease PLD4 | chr14 | GO:0140097 | Not Cancer Driver | No | 46 | 0.091 | 76 | 10 | 0.132 | 0 |
| POLB | POLB | P06746 | DNA polymerase beta | chr8 | GO:0140097 | Not Cancer Driver | No | 43 | 0.128 | 87 | 11 | 0.126 | 0 |
| POLE | POLE | Q07864 | DNA polymerase epsilon catalytic subunit A | chr12 | GO:0140097 | Census, Compendium | Yes | 409 | 0.179 | 239 | 44 | 0.184 | 3 |
| POLL_ENST00000370169 | POLL | Q9UGP5 | DNA polymerase lambda | chr10 | GO:0140097 | Not Cancer Driver | No | 69 | 0.12 | 215 | 16 | 0.074 | 0 |
| POLQ | POLQ | O75417 | DNA polymerase theta | chr3 | GO:0140097 | Census, Compendium | Yes | 364 | 0.141 | 949 | 135 | 0.142 | 0 |
| RAD1 | RAD1 | O60671 | Cell cycle checkpoint protein RAD1 | chr5 | GO:0140097 | Not Cancer Driver | No | 29 | 0.103 | 4 | 1 | 0.25 | 0 |
| RAD17 | RAD17 | O75943 | Cell cycle checkpoint protein RAD17 | chr5 | GO:0140097 | Census | Yes | 78 | 0.115 | 207 | 19 | 0.092 | 0 |
| RAD50 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0140097 | Not Cancer Driver | No | 157 | 0.12 | 730 | 84 | 0.115 | 0 |
| RAD51C | RAD51C | O43502 | DNA repair protein RAD51 homolog 3 | chr17 | GO:0140097 | Not Cancer Driver | No | 47 | 0.125 | 18 | 2 | 0.111 | 6 |
| RAD51_ENST00000267868 | RAD51 | Q06609 | DNA repair protein RAD51 homolog 1 | chr15 | GO:0140097 | Not Cancer Driver | No | 42 | 0.124 | 47 | 5 | 0.106 | 3 |
| RAD54B | RAD54B | Q9Y620 | DNA repair and recombination protein RAD54B | chr8 | GO:0140097 | Not Cancer Driver | No | 112 | 0.123 | 120 | 16 | 0.133 | 0 |
| RAD54L_ENST00000442598 | RAD54L | Q92698 | DNA repair and recombination protein RAD54-like | chr1 | GO:0140097 | Not Cancer Driver | No | 79 | 0.106 | 124 | 13 | 0.105 | 0 |
| RAD9A | RAD9A | Q99638 | Cell cycle checkpoint control protein RAD9A | chr11 | GO:0140097 | Not Cancer Driver | No | 34 | 0.087 | 135 | 7 | 0.052 | 0 |
| RAG1 | RAG1 | P15918 | V(D)J recombination-activating protein 1 | chr11 | GO:0140097 | Not Cancer Driver | No | 204 | 0.196 | 208 | 43 | 0.207 | 36 |
| RBBP8_ENST00000327155 | RBBP8 | Q99708 | DNA endonuclease RBBP8 | chr18 | GO:0140097 | Not Cancer Driver | No | 99 | 0.11 | 750 | 76 | 0.101 | 1 |
| RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | GO:0140097 | Census, Compendium | Yes | 138 | 0.114 | 608 | 71 | 0.117 | 1 |
| RECQL5 | RECQL5 | O94762 | ATP-dependent DNA helicase Q5 | chr17 | GO:0140097 | Not Cancer Driver | No | 132 | 0.133 | 495 | 71 | 0.143 | 0 |
| RECQL_ENST00000421138 | RECQL | P46063 | ATP-dependent DNA helicase Q1 | chr12 | GO:0140097 | Not Cancer Driver | No | 67 | 0.103 | 91 | 5 | 0.055 | 0 |
| RFC1 | RFC1 | P35251 | Replication factor C subunit 1 | chr4 | GO:0140097 | Not Cancer Driver | No | 147 | 0.128 | 674 | 82 | 0.122 | 0 |
| RFC2 | RFC2 | P35250 | Replication factor C subunit 2 | chr7 | GO:0140097 | Not Cancer Driver | No | 45 | 0.127 | 39 | 6 | 0.154 | 0 |
| RFC3 | RFC3 | P40938 | Replication factor C subunit 3 | chr13 | GO:0140097 | Not Cancer Driver | No | 31 | 0.087 | 13 | 1 | 0.077 | 0 |
| RFC4_ENST00000296273 | RFC4 | P35249 | Replication factor C subunit 4 | chr3 | GO:0140097 | Not Cancer Driver | No | 58 | 0.16 | 50 | 8 | 0.16 | 0 |
| RFC5 | RFC5 | P40937 | Replication factor C subunit 5 | chr12 | GO:0140097 | Not Cancer Driver | No | 38 | 0.112 | 20 | 1 | 0.05 | 0 |
| RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:0140097 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
| RUVBL1 | RUVBL1 | Q9Y265 | RuvB-like 1 | chr3 | GO:0140097 | Not Cancer Driver | No | 54 | 0.118 | 67 | 7 | 0.104 | 0 |
| RUVBL2 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | GO:0140097 | Not Cancer Driver | No | 62 | 0.134 | 100 | 13 | 0.13 | 0 |
| SETMAR | SETMAR | Q53H47 | Histone-lysine N-methyltransferase SETMAR | chr3 | GO:0140097 | Not Cancer Driver | No | 62 | 0.091 | 154 | 12 | 0.078 | 0 |
| SLX1B | SLX1B | Q9BQ83 | Structure-specific endonuclease subunit SLX1 | chr16 | GO:0140097 | Not Cancer Driver | No | 3 | 0.011 | 80 | 1 | 0.013 | 0 |
| SMARCA1_ENST00000371122 | SMARCA1 | P28370 | Probable global transcription activator SNF2L1 | chrX | GO:0140097 | Compendium | Yes | 143 | 0.136 | 309 | 41 | 0.133 | 0 |
| SMARCA5 | SMARCA5 | O60264 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 | chr4 | GO:0140097 | Not Cancer Driver | No | 116 | 0.11 | 363 | 48 | 0.132 | 0 |
| SMARCAD1_ENST00000354268 | SMARCAD1 | Q9H4L7 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 | chr4 | GO:0140097 | Not Cancer Driver | No | 129 | 0.126 | 388 | 50 | 0.129 | 0 |
| SMC3 | SMC3 | Q9UQE7 | Structural maintenance of chromosomes protein 3 | chr10 | GO:0140097 | Not Cancer Driver | No | 149 | 0.122 | 605 | 70 | 0.116 | 0 |
| SMUG1 | SMUG1 | Q53HV7 | Single-strand selective monofunctional uracil DNA glycosylase | chr12 | GO:0140097 | Not Cancer Driver | No | 33 | 0.122 | 46 | 2 | 0.043 | 0 |
| SPO11 | SPO11 | Q9Y5K1 | Meiotic recombination protein SPO11 | chr20 | GO:0140097 | Not Cancer Driver | No | 59 | 0.149 | 26 | 5 | 0.192 | 0 |
| TDG | TDG | Q13569 | G/T mismatch-specific thymine DNA glycosylase | chr12 | GO:0140097 | Not Cancer Driver | No | 75 | 0.183 | 185 | 31 | 0.168 | 0 |
| TDP1_ENST00000393454 | TDP1 | Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | chr14 | GO:0140097 | Not Cancer Driver | No | 81 | 0.133 | 179 | 25 | 0.14 | 1 |
| TDP2 | TDP2 | O95551 | Tyrosyl-DNA phosphodiesterase 2 | chr6 | GO:0140097 | Not Cancer Driver | No | 55 | 0.152 | 80 | 10 | 0.125 | 0 |
| TEFM | TEFM | Q96QE5 | Transcription elongation factor, mitochondrial | chr17 | GO:0140097 | Not Cancer Driver | No | 37 | 0.103 | 26 | 5 | 0.192 | 0 |
| TERT | TERT | O14746 | Telomerase reverse transcriptase | chr5 | GO:0140097 | Census | Yes | 110 | 0.097 | 212 | 16 | 0.075 | 31 |
| THAP9 | THAP9 | Q9H5L6 | DNA transposase THAP9 | chr4 | GO:0140097 | Not Cancer Driver | No | 82 | 0.091 | 46 | 6 | 0.13 | 0 |
| TOP1 | TOP1 | P11387 | DNA topoisomerase 1 | chr20 | GO:0140097 | Census, Compendium | Yes | 93 | 0.122 | 391 | 53 | 0.136 | 0 |
| TOP1MT | TOP1MT | Q969P6 | DNA topoisomerase I, mitochondrial | chr8 | GO:0140097 | Not Cancer Driver | No | 102 | 0.17 | 171 | 32 | 0.187 | 0 |
| TOP2A | TOP2A | P11388 | DNA topoisomerase 2-alpha | chr17 | GO:0140097 | Compendium | Yes | 150 | 0.098 | 508 | 59 | 0.116 | 0 |
| TOP2B | TOP2B | Q02880 | DNA topoisomerase 2-beta | chr3 | GO:0140097 | Not Cancer Driver | No | 154 | 0.095 | 543 | 46 | 0.085 | 0 |
| TOP3A | TOP3A | Q13472 | DNA topoisomerase 3-alpha | chr17 | GO:0140097 | Not Cancer Driver | No | 103 | 0.103 | 293 | 31 | 0.106 | 2 |
| TOP3B_ENST00000357179 | TOP3B | O95985 | DNA topoisomerase 3-beta-1 | chr22 | GO:0140097 | Not Cancer Driver | No | 102 | 0.118 | 151 | 17 | 0.113 | 0 |
| TREX1_ENST00000625293 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0140097 | Not Cancer Driver | No | 26 | 0.083 | 98 | 10 | 0.102 | 18 |
| TREX2_ENST00000370231 | TREX2 | Q9BQ50 | Three prime repair exonuclease 2 | chrX | GO:0140097 | Not Cancer Driver | No | 33 | 0.14 | 23 | 6 | 0.261 | 0 |
| TWNK | TWNK | Q96RR1 | Twinkle mtDNA helicase | chr10 | GO:0140097 | Not Cancer Driver | No | 95 | 0.139 | 135 | 11 | 0.081 | 38 |
| UNG | UNG | P13051 | Uracil-DNA glycosylase | chr12 | GO:0140097 | Not Cancer Driver | No | 34 | 0.109 | 96 | 13 | 0.135 | 1 |
| UPF1 | UPF1 | Q92900 | Regulator of nonsense transcripts 1 | chr19 | GO:0140097 | Not Cancer Driver | No | 146 | 0.129 | 329 | 36 | 0.109 | 0 |
| VRTN | VRTN | Q9H8Y1 | Vertnin | chr14 | GO:0140097 | Not Cancer Driver | No | 153 | 0.218 | 132 | 27 | 0.205 | 0 |
| WRN | WRN | Q14191 | Werner syndrome ATP-dependent helicase | chr8 | GO:0140097 | Census, Compendium | Yes | 164 | 0.115 | 373 | 41 | 0.11 | 2 |
| XRCC1 | XRCC1 | P18887 | DNA repair protein XRCC1 | chr19 | GO:0140097 | Not Cancer Driver | No | 85 | 0.134 | 426 | 53 | 0.124 | 1 |
| XRCC3_ENST00000352127 | XRCC3 | O43542 | DNA repair protein XRCC3 | chr14 | GO:0140097 | Not Cancer Driver | No | 24 | 0.069 | 35 | 2 | 0.057 | 1 |
| XRCC5_ENST00000392132 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | GO:0140097 | Not Cancer Driver | No | 87 | 0.119 | 118 | 11 | 0.093 | 0 |
| XRCC6 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | GO:0140097 | Not Cancer Driver | No | 66 | 0.108 | 140 | 12 | 0.086 | 0 |
| ZGRF1 | ZGRF1 | Q86YA3 | Protein ZGRF1 | chr4 | GO:0140097 | Not Cancer Driver | No | 216 | 0.103 | 881 | 95 | 0.108 | 0 |