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Total number of protein in "GO:0120025" GO term:  129

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA7 ABCA7 Q8IZY2 Phospholipid-transporting ATPase ABCA7 chr19 GO:0120025 Not Cancer Driver No 260 0.121 402 35 0.087 1
ACTN1_ENST00000193403 ACTN1 P12814 Alpha-actinin-1 chr14 GO:0120025 Not Cancer Driver No 108 0.121 195 30 0.154 6
ACTN2_ENST00000366578 ACTN2 P35609 Alpha-actinin-2 chr1 GO:0120025 Not Cancer Driver No 227 0.254 131 29 0.221 9
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:0120025 Not Cancer Driver No 123 0.137 135 13 0.096 0
ACTN4 ACTN4 O43707 Alpha-actinin-4 chr19 GO:0120025 Not Cancer Driver No 131 0.144 244 42 0.172 8
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 GO:0120025 Not Cancer Driver No 64 0.092 67 4 0.06 9
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0120025 Census Yes 474 0.121 2281 268 0.117 1
ANLN ANLN Q9NQW6 Anillin chr7 GO:0120025 Not Cancer Driver No 144 0.128 767 104 0.136 2
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0120025 Not Cancer Driver No 128 0.166 418 71 0.17 17
AQP4 AQP4 P55087 Aquaporin-4 chr18 GO:0120025 Not Cancer Driver No 50 0.155 30 9 0.3 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 GO:0120025 Not Cancer Driver No 49 0.117 154 13 0.084 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0120025 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATP1A4 ATP1A4 Q13733 Sodium/potassium-transporting ATPase subunit alpha-4 chr1 GO:0120025 Not Cancer Driver No 195 0.19 117 24 0.205 0
ATP1B2 ATP1B2 P14415 Sodium/potassium-transporting ATPase subunit beta-2 chr17 GO:0120025 Not Cancer Driver No 40 0.138 16 6 0.375 0
ATP2B3_ENST00000349466 ATP2B3 Q16720 Plasma membrane calcium-transporting ATPase 3 chrX GO:0120025 Census Yes 245 0.201 328 74 0.226 2
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0120025 Not Cancer Driver No 65 0.11 456 42 0.092 5
BST1 BST1 Q10588 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 chr4 GO:0120025 Not Cancer Driver No 40 0.126 11 0 0.0 0
C1QL1 C1QL1 O75973 C1q-related factor chr17 GO:0120025 Not Cancer Driver No 25 0.097 126 5 0.04 0
CACNG2 CACNG2 Q9Y698 Voltage-dependent calcium channel gamma-2 subunit chr22 GO:0120025 Not Cancer Driver No 57 0.176 90 16 0.178 1
CACNG7 CACNG7 P62955 Voltage-dependent calcium channel gamma-7 subunit chr19 GO:0120025 Not Cancer Driver No 99 0.36 9 1 0.111 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0120025 Not Cancer Driver No 81 0.116 46 11 0.239 0
CFAP45 CFAP45 Q9UL16 Cilia- and flagella-associated protein 45 chr1 GO:0120025 Not Cancer Driver No 126 0.229 493 120 0.243 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0120025 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNGA3 CNGA3 Q16281 Cyclic nucleotide-gated cation channel alpha-3 chr2 GO:0120025 Not Cancer Driver No 183 0.264 217 67 0.309 53
CNP CNP P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase chr17 GO:0120025 Not Cancer Driver No 36 0.086 71 2 0.028 0
CPEB3_ENST00000265997 CPEB3 Q8NE35 Cytoplasmic polyadenylation element-binding protein 3 chr10 GO:0120025 Census, Compendium Yes 66 0.095 414 28 0.068 0
CRB1 CRB1 P82279 Protein crumbs homolog 1 chr1 GO:0120025 Not Cancer Driver No 464 0.33 28 5 0.179 74
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0120025 Not Cancer Driver No 131 0.11 681 68 0.1 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0120025 Not Cancer Driver No 116 0.16 232 55 0.237 0
DNAH11 DNAH11 Q96DT5 Dynein axonemal heavy chain 11 chr7 GO:0120025 Not Cancer Driver No 885 0.196 221 36 0.163 3
EEA1 EEA1 Q15075 Early endosome antigen 1 chr12 GO:0120025 Not Cancer Driver No 151 0.107 1168 126 0.108 0
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 GO:0120025 Not Cancer Driver No 35 0.111 59 6 0.102 0
ENKUR ENKUR Q8TC29 Enkurin chr10 GO:0120025 Not Cancer Driver No 53 0.207 157 39 0.248 0
EZR EZR P15311 Ezrin chr6 GO:0120025 Census Yes 66 0.113 295 35 0.119 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0120025 Not Cancer Driver No 55 0.139 7 2 0.286 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0120025 Not Cancer Driver No 75 0.144 243 38 0.156 1
FHOD1 FHOD1 Q9Y613 FH1/FH2 domain-containing protein 1 chr16 GO:0120025 Not Cancer Driver No 151 0.13 575 82 0.143 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0120025 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 GO:0120025 Not Cancer Driver No 56 0.131 20 3 0.15 0
FMNL1 FMNL1 O95466 Formin-like protein 1 chr17 GO:0120025 Not Cancer Driver No 115 0.105 524 32 0.061 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0120025 Not Cancer Driver No 124 0.196 327 70 0.214 3
FSCN1 FSCN1 Q16658 Fascin chr7 GO:0120025 Not Cancer Driver No 58 0.118 81 5 0.062 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 GO:0120025 Not Cancer Driver No 88 0.142 312 53 0.17 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 GO:0120025 Not Cancer Driver No 68 0.101 388 42 0.108 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0120025 Not Cancer Driver No 92 0.171 70 13 0.186 0
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 GO:0120025 Not Cancer Driver No 65 0.15 288 42 0.146 62
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:0120025 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0120025 Not Cancer Driver No 34 0.15 0 0 0.0 46
GJC2 GJC2 Q5T442 Gap junction gamma-2 protein chr1 GO:0120025 Not Cancer Driver No 33 0.075 225 10 0.044 6
GLUL_ENST00000331872 GLUL P15104 Glutamine synthetase chr1 GO:0120025 Not Cancer Driver No 66 0.177 104 21 0.202 2
GRIA1_ENST00000285900 GRIA1 P42261 Glutamate receptor 1 chr5 GO:0120025 Not Cancer Driver No 303 0.334 104 45 0.433 0
GRM2 GRM2 Q14416 Metabotropic glutamate receptor 2 chr3 GO:0120025 Not Cancer Driver No 143 0.164 24 3 0.125 0
GRM3 GRM3 Q14832 Metabotropic glutamate receptor 3 chr7 GO:0120025 Census Yes 323 0.367 8 3 0.375 0
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0120025 Not Cancer Driver No 312 0.257 323 51 0.158 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0120025 Not Cancer Driver No 55 0.114 180 8 0.044 0
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0120025 Not Cancer Driver No 105 0.223 44 8 0.182 0
ICAM2_ENST00000579687 ICAM2 P13598 Intercellular adhesion molecule 2 chr17 GO:0120025 Not Cancer Driver No 39 0.142 19 1 0.053 0
ITGA3 ITGA3 P26006 Integrin alpha-3 chr17 GO:0120025 Not Cancer Driver No 106 0.101 129 18 0.14 3
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0120025 Not Cancer Driver No 103 0.129 84 10 0.119 0
KCNJ10 KCNJ10 P78508 ATP-sensitive inward rectifier potassium channel 10 chr1 GO:0120025 Not Cancer Driver No 78 0.206 28 10 0.357 8
KCNK2 KCNK2 O95069 Potassium channel subfamily K member 2 chr1 GO:0120025 Not Cancer Driver No 109 0.256 40 10 0.25 0
KLHL41 KLHL41 O60662 Kelch-like protein 41 chr2 GO:0120025 Not Cancer Driver No 69 0.114 18 2 0.111 1
LDB3_ENST00000361373 LDB3 O75112 LIM domain-binding protein 3 chr10 GO:0120025 Not Cancer Driver No 107 0.147 529 71 0.134 4
LRRC4B_ENST00000389201 LRRC4B Q9NT99 Leucine-rich repeat-containing protein 4B chr19 GO:0120025 Not Cancer Driver No 141 0.198 245 46 0.188 0
MAP1A MAP1A P78559 Microtubule-associated protein 1A chr15 GO:0120025 Not Cancer Driver No 369 0.132 2443 311 0.127 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0120025 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP2 MAP2 P11137 Microtubule-associated protein 2 chr2 GO:0120025 Compendium Yes 367 0.201 1726 340 0.197 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0120025 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0120025 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 GO:0120025 Not Cancer Driver No 79 0.111 444 40 0.09 1
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0120025 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0120025 Not Cancer Driver No 128 0.169 750 126 0.168 18
MERTK_ENST00000421804 MERTK Q12866 Tyrosine-protein kinase Mer chr2 GO:0120025 Not Cancer Driver No 175 0.175 159 31 0.195 3
MSN MSN P26038 Moesin chrX GO:0120025 Census, Compendium Yes 108 0.187 286 56 0.196 1
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0120025 Not Cancer Driver No 7 0.103 0 0 0.0 0
MYH9 MYH9 P35579 Myosin-9 chr22 GO:0120025 Census, Compendium Yes 310 0.158 1120 160 0.143 17
MYO1D MYO1D O94832 Unconventional myosin-Id chr17 GO:0120025 Not Cancer Driver No 126 0.125 61 6 0.098 0
MYOZ1 MYOZ1 Q9NP98 Myozenin-1 chr10 GO:0120025 Not Cancer Driver No 49 0.164 223 39 0.175 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0120025 Not Cancer Driver No 62 0.108 153 11 0.072 0
NFIB_ENST00000380959 NFIB O00712 Nuclear factor 1 B-type chr9 GO:0120025 Census Yes 63 0.15 254 36 0.142 3
NSMF NSMF Q6X4W1 NMDA receptor synaptonuclear signaling and neuronal migration factor chr9 GO:0120025 Not Cancer Driver No 46 0.087 287 19 0.066 2
OSBP2 OSBP2 Q969R2 Oxysterol-binding protein 2 chr22 GO:0120025 Not Cancer Driver No 101 0.11 432 41 0.095 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0120025 Not Cancer Driver No 51 0.086 14 2 0.143 0
PANX1 PANX1 Q96RD7 Pannexin-1 chr11 GO:0120025 Not Cancer Driver No 54 0.127 45 7 0.156 2
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0120025 Not Cancer Driver No 109 0.408 142 62 0.437 0
PEX6 PEX6 Q13608 Peroxisome assembly factor 2 chr6 GO:0120025 Not Cancer Driver No 72 0.073 177 9 0.051 11
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0120025 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP5K1B PIP5K1B O14986 Phosphatidylinositol 4-phosphate 5-kinase type-1 beta chr9 GO:0120025 Not Cancer Driver No 94 0.174 162 36 0.222 0
PIP5K1C_ENST00000335312 PIP5K1C O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma chr19 GO:0120025 Not Cancer Driver No 98 0.147 360 60 0.167 1
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0120025 Not Cancer Driver No 108 0.134 148 23 0.155 11
PROM2_ENST00000403131 PROM2 Q8N271 Prominin-2 chr2 GO:0120025 Not Cancer Driver No 111 0.133 34 4 0.118 0
PSTPIP1 PSTPIP1 O43586 Proline-serine-threonine phosphatase-interacting protein 1 chr15 GO:0120025 Not Cancer Driver No 46 0.111 225 26 0.116 3
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0120025 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0120025 Census, Compendium Yes 315 0.241 462 107 0.232 0
RAB25 RAB25 P57735 Ras-related protein Rab-25 chr1 GO:0120025 Not Cancer Driver No 26 0.122 32 5 0.156 0
RAB3IP RAB3IP Q96QF0 Rab-3A-interacting protein chr12 GO:0120025 Not Cancer Driver No 85 0.179 227 33 0.145 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0120025 Census, Compendium Yes 89 0.137 169 38 0.225 22
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0120025 Not Cancer Driver No 184 0.136 780 103 0.132 0
SACS SACS Q9NZJ4 Sacsin chr13 GO:0120025 Not Cancer Driver No 683 0.149 272 41 0.151 24
SCN11A SCN11A Q9UI33 Sodium channel protein type 11 subunit alpha chr3 GO:0120025 Not Cancer Driver No 475 0.265 198 61 0.308 9
SCN7A_ENST00000409855 SCN7A Q01118 Sodium channel protein type 7 subunit alpha chr2 GO:0120025 Not Cancer Driver No 395 0.235 171 43 0.251 0
SDC3 SDC3 O75056 Syndecan-3 chr1 GO:0120025 Not Cancer Driver No 47 0.106 380 39 0.103 0
SDCCAG8 SDCCAG8 Q86SQ7 Serologically defined colon cancer antigen 8 chr1 GO:0120025 Not Cancer Driver No 110 0.154 487 73 0.15 0
SDF4 SDF4 Q9BRK5 45 kDa calcium-binding protein chr1 GO:0120025 Not Cancer Driver No 48 0.133 187 30 0.16 0
SELPLG_ENST00000550948 SELPLG Q14242 P-selectin glycoprotein ligand 1 chr12 GO:0120025 Not Cancer Driver No 68 0.165 297 48 0.162 0
SEZ6 SEZ6 Q53EL9 Seizure protein 6 homolog chr17 GO:0120025 Not Cancer Driver No 120 0.121 345 54 0.157 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0120025 Not Cancer Driver No 56 0.144 85 17 0.2 0
SLC17A8 SLC17A8 Q8NDX2 Vesicular glutamate transporter 3 chr12 GO:0120025 Not Cancer Driver No 134 0.228 95 30 0.316 1
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0120025 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC1A2 SLC1A2 P43004 Excitatory amino acid transporter 2 chr11 GO:0120025 Not Cancer Driver No 77 0.134 81 7 0.086 3
SLC2A13 SLC2A13 Q96QE2 Proton myo-inositol cotransporter chr12 GO:0120025 Not Cancer Driver No 79 0.122 52 4 0.077 0
SLC30A3 SLC30A3 Q99726 Zinc transporter 3 chr2 GO:0120025 Not Cancer Driver No 56 0.144 97 18 0.186 0
SLC4A10 SLC4A10 Q6U841 Sodium-driven chloride bicarbonate exchanger chr2 GO:0120025 Not Cancer Driver No 221 0.198 340 68 0.2 0
SLC4A8 SLC4A8 Q2Y0W8 Electroneutral sodium bicarbonate exchanger 1 chr12 GO:0120025 Not Cancer Driver No 176 0.161 276 41 0.149 0
SLC7A11 SLC7A11 Q9UPY5 Cystine/glutamate transporter chr4 GO:0120025 Not Cancer Driver No 70 0.14 15 2 0.133 0
SNX5_ENST00000377759 SNX5 Q9Y5X3 Sorting nexin-5 chr20 GO:0120025 Not Cancer Driver No 33 0.082 91 13 0.143 0
SPN_ENST00000395389 SPN P16150 Leukosialin chr16 GO:0120025 Not Cancer Driver No 46 0.115 357 35 0.098 0
SPTBN4_ENST00000598249 SPTBN4 Q9H254 Spectrin beta chain, non-erythrocytic 4 chr19 GO:0120025 Not Cancer Driver No 312 0.122 866 103 0.119 0
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0120025 Not Cancer Driver No 35 0.135 0 0 0.0 0
SRD5A2 SRD5A2 P31213 3-oxo-5-alpha-steroid 4-dehydrogenase 2 chr2 GO:0120025 Not Cancer Driver No 48 0.189 0 0 0.0 21
SYT4 SYT4 Q9H2B2 Synaptotagmin-4 chr18 GO:0120025 Not Cancer Driver No 111 0.261 107 41 0.383 0
SYT5 SYT5 O00445 Synaptotagmin-5 chr19 GO:0120025 Not Cancer Driver No 60 0.155 110 11 0.1 0
TMEM50A TMEM50A O95807 Transmembrane protein 50A chr1 GO:0120025 Not Cancer Driver No 24 0.153 0 0 0.0 0
TNN TNN Q9UQP3 Tenascin-N chr1 GO:0120025 Not Cancer Driver No 426 0.328 637 231 0.363 0
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 GO:0120025 Not Cancer Driver No 33 0.116 234 29 0.124 8
TRIM46 TRIM46 Q7Z4K8 Tripartite motif-containing protein 46 chr1 GO:0120025 Not Cancer Driver No 115 0.152 173 30 0.173 0
TTC25 ODAD4 Q96NG3 Outer dynein arm-docking complex subunit 4 chr17 GO:0120025 Not Cancer Driver No 62 0.092 264 25 0.095 0
VAMP7_ENST00000286448 VAMP7 P51809 Vesicle-associated membrane protein 7 chrX GO:0120025 Not Cancer Driver No 38 0.173 4 1 0.25 0
YKT6 YKT6 O15498 Synaptobrevin homolog YKT6 chr7 GO:0120025 Not Cancer Driver No 19 0.096 21 2 0.095 0