Total number of protein in "GO:0099503" GO term: 102
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCA12 | ABCA12 | Q86UK0 | Glucosylceramide transporter ABCA12 | chr2 | GO:0099503 | Not Cancer Driver | No | 511 | 0.197 | 136 | 23 | 0.169 | 14 |
| ABCA3 | ABCA3 | Q99758 | Phospholipid-transporting ATPase ABCA3 | chr16 | GO:0099503 | Not Cancer Driver | No | 224 | 0.131 | 77 | 4 | 0.052 | 13 |
| ADAM8 | ADAM8 | P78325 | Disintegrin and metalloproteinase domain-containing protein 8 | chr10 | GO:0099503 | Not Cancer Driver | No | 82 | 0.1 | 230 | 13 | 0.057 | 0 |
| ANXA11 | ANXA11 | P50995 | Annexin A11 | chr10 | GO:0099503 | Not Cancer Driver | No | 63 | 0.125 | 244 | 31 | 0.127 | 1 |
| ANXA3 | ANXA3 | P12429 | Annexin A3 | chr4 | GO:0099503 | Not Cancer Driver | No | 53 | 0.164 | 22 | 4 | 0.182 | 0 |
| ASTL | ASTL | Q6HA08 | Astacin-like metalloendopeptidase | chr2 | GO:0099503 | Not Cancer Driver | No | 101 | 0.234 | 179 | 44 | 0.246 | 0 |
| AZU1 | AZU1 | P20160 | Azurocidin | chr19 | GO:0099503 | Not Cancer Driver | No | 42 | 0.167 | 53 | 13 | 0.245 | 0 |
| BAIAP3 | BAIAP3 | O94812 | BAI1-associated protein 3 | chr16 | GO:0099503 | Not Cancer Driver | No | 170 | 0.143 | 230 | 35 | 0.152 | 0 |
| BICD1 | BICD1 | Q96G01 | Protein bicaudal D homolog 1 | chr12 | GO:0099503 | Not Cancer Driver | No | 124 | 0.127 | 656 | 86 | 0.131 | 0 |
| CALR | CALR | P27797 | Calreticulin | chr19 | GO:0099503 | Census | Yes | 45 | 0.108 | 245 | 31 | 0.127 | 0 |
| CAMP | CAMP | P49913 | Cathelicidin antimicrobial peptide | chr3 | GO:0099503 | Not Cancer Driver | No | 25 | 0.147 | 48 | 4 | 0.083 | 0 |
| CHGA | CHGA | P10645 | Chromogranin-A | chr14 | GO:0099503 | Not Cancer Driver | No | 46 | 0.101 | 421 | 44 | 0.105 | 0 |
| CKAP4 | CKAP4 | Q07065 | Cytoskeleton-associated protein 4 | chr12 | GO:0099503 | Not Cancer Driver | No | 73 | 0.121 | 409 | 55 | 0.134 | 0 |
| CLCN3_ENST00000513761 | CLCN3 | P51790 | H(+)/Cl(-) exchange transporter 3 | chr4 | GO:0099503 | Not Cancer Driver | No | 105 | 0.128 | 88 | 7 | 0.08 | 0 |
| CLU_ENST00000523500 | CLU | P10909 | Clusterin | chr8 | GO:0099503 | Not Cancer Driver | No | 69 | 0.154 | 156 | 27 | 0.173 | 0 |
| CRACR2A | CRACR2A | Q9BSW2 | EF-hand calcium-binding domain-containing protein 4B | chr12 | GO:0099503 | Not Cancer Driver | No | 88 | 0.12 | 436 | 60 | 0.138 | 0 |
| CRHBP | CRHBP | P24387 | Corticotropin-releasing factor-binding protein | chr5 | GO:0099503 | Not Cancer Driver | No | 61 | 0.189 | 0 | 0 | 0.0 | 0 |
| CTSH | CTSH | P09668 | Pro-cathepsin H | chr15 | GO:0099503 | Not Cancer Driver | No | 45 | 0.134 | 4 | 0 | 0.0 | 0 |
| CTSL | CTSL | P07711 | Procathepsin L | chr9 | GO:0099503 | Not Cancer Driver | No | 47 | 0.141 | 34 | 4 | 0.118 | 0 |
| DEFA4 | DEFA4 | P12838 | Defensin alpha 4 | chr8 | GO:0099503 | Not Cancer Driver | No | 35 | 0.361 | 17 | 5 | 0.294 | 0 |
| DENND4C_ENST00000602925 | DENND4C | Q5VZ89 | DENN domain-containing protein 4C | chr9 | GO:0099503 | Not Cancer Driver | No | 190 | 0.1 | 710 | 69 | 0.097 | 0 |
| DMXL2_ENST00000251076 | DMXL2 | Q8TDJ6 | DmX-like protein 2 | chr15 | GO:0099503 | Not Cancer Driver | No | 428 | 0.141 | 738 | 102 | 0.138 | 2 |
| DNASE1_ENST00000246949 | DNASE1 | P24855 | Deoxyribonuclease-1 | chr16 | GO:0099503 | Not Cancer Driver | No | 24 | 0.085 | 0 | 0 | 0.0 | 0 |
| DYNLT1 | DYNLT1 | P63172 | Dynein light chain Tctex-type 1 | chr6 | GO:0099503 | Not Cancer Driver | No | 7 | 0.062 | 1 | 0 | 0.0 | 0 |
| ECE1 | ECE1 | P42892 | Endothelin-converting enzyme 1 | chr1 | GO:0099503 | Not Cancer Driver | No | 118 | 0.153 | 99 | 26 | 0.263 | 1 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0099503 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| F5 | F5 | P12259 | Coagulation factor V | chr1 | GO:0099503 | Not Cancer Driver | No | 455 | 0.205 | 974 | 223 | 0.229 | 7 |
| FGA | FGA | P02671 | Fibrinogen alpha chain | chr4 | GO:0099503 | Not Cancer Driver | No | 245 | 0.283 | 522 | 149 | 0.285 | 7 |
| FGB | FGB | P02675 | Fibrinogen beta chain | chr4 | GO:0099503 | Not Cancer Driver | No | 89 | 0.181 | 143 | 29 | 0.203 | 7 |
| FGG | FGG | P02679 | Fibrinogen gamma chain | chr4 | GO:0099503 | Not Cancer Driver | No | 81 | 0.179 | 53 | 8 | 0.151 | 8 |
| GNAI3 | GNAI3 | P08754 | Guanine nucleotide-binding protein G(i) subunit alpha-3 | chr1 | GO:0099503 | Not Cancer Driver | No | 42 | 0.119 | 11 | 0 | 0.0 | 1 |
| HEXA_ENST00000268097 | HEXA | P06865 | Beta-hexosaminidase subunit alpha | chr15 | GO:0099503 | Not Cancer Driver | No | 59 | 0.112 | 5 | 1 | 0.2 | 49 |
| HEXB | HEXB | P07686 | Beta-hexosaminidase subunit beta | chr5 | GO:0099503 | Not Cancer Driver | No | 45 | 0.081 | 0 | 0 | 0.0 | 9 |
| HPS4_ENST00000336873 | HPS4 | Q9NQG7 | Hermansky-Pudlak syndrome 4 protein | chr22 | GO:0099503 | Not Cancer Driver | No | 96 | 0.136 | 343 | 57 | 0.166 | 0 |
| KIF1A_ENST00000320389 | KIF1A | Q12756 | Kinesin-like protein KIF1A | chr2 | GO:0099503 | Not Cancer Driver | No | 275 | 0.163 | 594 | 79 | 0.133 | 35 |
| KLK5_ENST00000593428 | KLK5 | Q9Y337 | Kallikrein-5 | chr19 | GO:0099503 | Not Cancer Driver | No | 69 | 0.235 | 75 | 16 | 0.213 | 0 |
| KLK7 | KLK7 | P49862 | Kallikrein-7 | chr19 | GO:0099503 | Not Cancer Driver | No | 43 | 0.17 | 38 | 8 | 0.211 | 0 |
| KRTDAP | KRTDAP | P60985 | Keratinocyte differentiation-associated protein | chr19 | GO:0099503 | Not Cancer Driver | No | 19 | 0.192 | 19 | 3 | 0.158 | 0 |
| LTF | LTF | P02788 | Lactotransferrin | chr3 | GO:0099503 | Not Cancer Driver | No | 131 | 0.185 | 21 | 4 | 0.19 | 0 |
| MMRN1 | MMRN1 | Q13201 | Multimerin-1 | chr4 | GO:0099503 | Not Cancer Driver | No | 241 | 0.196 | 373 | 75 | 0.201 | 0 |
| MPO | MPO | P05164 | Myeloperoxidase | chr17 | GO:0099503 | Not Cancer Driver | No | 149 | 0.2 | 52 | 12 | 0.231 | 3 |
| MYH9 | MYH9 | P35579 | Myosin-9 | chr22 | GO:0099503 | Census, Compendium | Yes | 310 | 0.158 | 1120 | 160 | 0.143 | 17 |
| MYO5A | MYO5A | Q9Y4I1 | Unconventional myosin-Va | chr15 | GO:0099503 | Census, Compendium | Yes | 224 | 0.121 | 497 | 58 | 0.117 | 0 |
| MYRIP | MYRIP | Q8NFW9 | Rab effector MyRIP | chr3 | GO:0099503 | Not Cancer Driver | No | 133 | 0.155 | 599 | 95 | 0.159 | 0 |
| NAPSA | NAPSA | O96009 | Napsin-A | chr19 | GO:0099503 | Not Cancer Driver | No | 58 | 0.138 | 14 | 1 | 0.071 | 0 |
| NLRP5 | NLRP5 | P59047 | NACHT, LRR and PYD domains-containing protein 5 | chr19 | GO:0099503 | Not Cancer Driver | No | 369 | 0.307 | 144 | 35 | 0.243 | 0 |
| NPY_ENST00000405982 | NPY | P01303 | Pro-neuropeptide Y | chr7 | GO:0099503 | Not Cancer Driver | No | 29 | 0.299 | 43 | 19 | 0.442 | 0 |
| OLFM4 | OLFM4 | Q6UX06 | Olfactomedin-4 | chr13 | GO:0099503 | Not Cancer Driver | No | 117 | 0.229 | 54 | 11 | 0.204 | 0 |
| OPRD1 | OPRD1 | P41143 | Delta-type opioid receptor | chr1 | GO:0099503 | Not Cancer Driver | No | 91 | 0.245 | 30 | 3 | 0.1 | 0 |
| PADI6 | PADI6 | Q6TGC4 | Protein-arginine deiminase type-6 | chr1 | GO:0099503 | Not Cancer Driver | No | 101 | 0.146 | 27 | 5 | 0.185 | 2 |
| PICALM | PICALM | Q13492 | Phosphatidylinositol-binding clathrin assembly protein | chr11 | GO:0099503 | Census | Yes | 89 | 0.137 | 320 | 42 | 0.131 | 0 |
| PLAT | PLAT | P00750 | Tissue-type plasminogen activator | chr8 | GO:0099503 | Not Cancer Driver | No | 89 | 0.158 | 15 | 2 | 0.133 | 0 |
| RAB10 | RAB10 | P61026 | Ras-related protein Rab-10 | chr2 | GO:0099503 | Not Cancer Driver | No | 19 | 0.095 | 28 | 2 | 0.071 | 0 |
| RAB12 | RAB12 | Q6IQ22 | Ras-related protein Rab-12 | chr18 | GO:0099503 | Not Cancer Driver | No | 22 | 0.09 | 72 | 3 | 0.042 | 0 |
| RAB13 | RAB13 | P51153 | Ras-related protein Rab-13 | chr1 | GO:0099503 | Not Cancer Driver | No | 19 | 0.094 | 40 | 0 | 0.0 | 0 |
| RAB15 | RAB15 | P59190 | Ras-related protein Rab-15 | chr14 | GO:0099503 | Not Cancer Driver | No | 18 | 0.085 | 50 | 5 | 0.1 | 0 |
| RAB27A_ENST00000336787 | RAB27A | P51159 | Ras-related protein Rab-27A | chr15 | GO:0099503 | Not Cancer Driver | No | 25 | 0.113 | 15 | 4 | 0.267 | 3 |
| RAB3D_ENST00000589655 | RAB3D | O95716 | Ras-related protein Rab-3D | chr19 | GO:0099503 | Not Cancer Driver | No | 37 | 0.169 | 46 | 6 | 0.13 | 0 |
| RAB3IL1 | RAB3IL1 | Q8TBN0 | Guanine nucleotide exchange factor for Rab-3A | chr11 | GO:0099503 | Not Cancer Driver | No | 41 | 0.107 | 217 | 18 | 0.083 | 0 |
| RAB3IP | RAB3IP | Q96QF0 | Rab-3A-interacting protein | chr12 | GO:0099503 | Not Cancer Driver | No | 85 | 0.179 | 227 | 33 | 0.145 | 0 |
| RAB4A | RAB4A | P20338 | Ras-related protein Rab-4A | chr1 | GO:0099503 | Not Cancer Driver | No | 26 | 0.119 | 32 | 11 | 0.344 | 0 |
| RAB4B_ENST00000357052 | RAB4B | P61018 | Ras-related protein Rab-4B | chr19 | GO:0099503 | Not Cancer Driver | No | 40 | 0.188 | 36 | 10 | 0.278 | 0 |
| RAB6A_ENST00000336083 | RAB6A | P20340 | Ras-related protein Rab-6A | chr11 | GO:0099503 | Not Cancer Driver | No | 22 | 0.106 | 45 | 6 | 0.133 | 0 |
| RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | GO:0099503 | Not Cancer Driver | No | 27 | 0.13 | 11 | 0 | 0.0 | 4 |
| SCG2 | SCG2 | P13521 | Secretogranin-2 | chr2 | GO:0099503 | Not Cancer Driver | No | 116 | 0.188 | 531 | 103 | 0.194 | 0 |
| SERPINA5_ENST00000554276 | SERPINA5 | P05154 | Plasma serine protease inhibitor | chr14 | GO:0099503 | Not Cancer Driver | No | 103 | 0.254 | 24 | 17 | 0.708 | 0 |
| SERPINE2_ENST00000258405 | SERPINE2 | P07093 | Glia-derived nexin | chr2 | GO:0099503 | Not Cancer Driver | No | 62 | 0.156 | 0 | 0 | 0.0 | 0 |
| SFTA3 | SFTA3 | P0C7M3 | Surfactant-associated protein 3 | chr14 | GO:0099503 | Not Cancer Driver | No | 22 | 0.234 | 13 | 2 | 0.154 | 0 |
| SFTPA1_ENST00000398636 | SFTPA1 | Q8IWL2 | Pulmonary surfactant-associated protein A1 | chr10 | GO:0099503 | Not Cancer Driver | No | 41 | 0.165 | 171 | 33 | 0.193 | 3 |
| SFTPA2 | SFTPA2 | Q8IWL1 | Pulmonary surfactant-associated protein A2 | chr10 | GO:0099503 | Not Cancer Driver | No | 53 | 0.214 | 174 | 43 | 0.247 | 7 |
| SFTPB_ENST00000519937 | SFTPB | P07988 | Pulmonary surfactant-associated protein B | chr2 | GO:0099503 | Not Cancer Driver | No | 57 | 0.15 | 37 | 6 | 0.162 | 1 |
| SFTPC | SFTPC | P11686 | Pulmonary surfactant-associated protein C | chr8 | GO:0099503 | Not Cancer Driver | No | 21 | 0.107 | 19 | 2 | 0.105 | 5 |
| SLC2A4 | SLC2A4 | P14672 | Solute carrier family 2, facilitated glucose transporter member 4 | chr17 | GO:0099503 | Not Cancer Driver | No | 71 | 0.139 | 43 | 8 | 0.186 | 1 |
| SLC6A5 | SLC6A5 | Q9Y345 | Sodium- and chloride-dependent glycine transporter 2 | chr11 | GO:0099503 | Not Cancer Driver | No | 181 | 0.227 | 169 | 38 | 0.225 | 7 |
| SLC6A9 | SLC6A9 | P48067 | Sodium- and chloride-dependent glycine transporter 1 | chr1 | GO:0099503 | Not Cancer Driver | No | 102 | 0.144 | 65 | 12 | 0.185 | 1 |
| SMPD1 | SMPD1 | P17405 | Sphingomyelin phosphodiesterase | chr11 | GO:0099503 | Not Cancer Driver | No | 93 | 0.147 | 51 | 4 | 0.078 | 111 |
| SNAP23 | SNAP23 | O00161 | Synaptosomal-associated protein 23 | chr15 | GO:0099503 | Not Cancer Driver | No | 18 | 0.085 | 179 | 16 | 0.089 | 0 |
| SOD1 | SOD1 | P00441 | Superoxide dismutase [Cu-Zn] | chr21 | GO:0099503 | Not Cancer Driver | No | 16 | 0.104 | 93 | 9 | 0.097 | 79 |
| SPARC | SPARC | P09486 | SPARC | chr5 | GO:0099503 | Not Cancer Driver | No | 60 | 0.198 | 69 | 5 | 0.072 | 2 |
| SPINK5_ENST00000256084 | SPINK5 | Q9NQ38 | Serine protease inhibitor Kazal-type 5 | chr5 | GO:0099503 | Not Cancer Driver | No | 168 | 0.158 | 590 | 102 | 0.173 | 0 |
| SPX | SPX | Q9BT56 | Spexin | chr12 | GO:0099503 | Not Cancer Driver | No | 22 | 0.19 | 40 | 8 | 0.2 | 0 |
| STX3 | STX3 | Q13277 | Syntaxin-3 | chr11 | GO:0099503 | Not Cancer Driver | No | 51 | 0.176 | 129 | 30 | 0.233 | 0 |
| STX4 | STX4 | Q12846 | Syntaxin-4 | chr16 | GO:0099503 | Not Cancer Driver | No | 50 | 0.168 | 152 | 20 | 0.132 | 0 |
| STX7 | STX7 | O15400 | Syntaxin-7 | chr6 | GO:0099503 | Not Cancer Driver | No | 29 | 0.111 | 164 | 14 | 0.085 | 0 |
| STXBP1_ENST00000373299 | STXBP1 | P61764 | Syntaxin-binding protein 1 | chr9 | GO:0099503 | Not Cancer Driver | No | 97 | 0.163 | 111 | 23 | 0.207 | 18 |
| STXBP2_ENST00000221283 | STXBP2 | Q15833 | Syntaxin-binding protein 2 | chr19 | GO:0099503 | Not Cancer Driver | No | 77 | 0.13 | 80 | 13 | 0.163 | 5 |
| STXBP3 | STXBP3 | O00186 | Syntaxin-binding protein 3 | chr1 | GO:0099503 | Not Cancer Driver | No | 59 | 0.1 | 64 | 9 | 0.141 | 0 |
| SYT1_ENST00000393240 | SYT1 | P21579 | Synaptotagmin-1 | chr12 | GO:0099503 | Not Cancer Driver | No | 104 | 0.246 | 103 | 36 | 0.35 | 5 |
| SYT2_ENST00000367268 | SYT2 | Q8N9I0 | Synaptotagmin-2 | chr1 | GO:0099503 | Not Cancer Driver | No | 73 | 0.174 | 141 | 24 | 0.17 | 3 |
| SYT4 | SYT4 | Q9H2B2 | Synaptotagmin-4 | chr18 | GO:0099503 | Not Cancer Driver | No | 111 | 0.261 | 107 | 41 | 0.383 | 0 |
| SYT5 | SYT5 | O00445 | Synaptotagmin-5 | chr19 | GO:0099503 | Not Cancer Driver | No | 60 | 0.155 | 110 | 11 | 0.1 | 0 |
| SYT7_ENST00000263846 | SYT7 | O43581 | Synaptotagmin-7 | chr11 | GO:0099503 | Not Cancer Driver | No | 63 | 0.156 | 132 | 25 | 0.189 | 0 |
| SYT8 | SYT8 | Q8NBV8 | Synaptotagmin-8 | chr11 | GO:0099503 | Not Cancer Driver | No | 41 | 0.102 | 129 | 22 | 0.171 | 0 |
| SYT9 | SYT9 | Q86SS6 | Synaptotagmin-9 | chr11 | GO:0099503 | Not Cancer Driver | No | 120 | 0.244 | 148 | 42 | 0.284 | 0 |
| THBS1 | THBS1 | P07996 | Thrombospondin-1 | chr15 | GO:0099503 | Not Cancer Driver | No | 188 | 0.161 | 320 | 58 | 0.181 | 0 |
| THBS2 | THBS2 | P35442 | Thrombospondin-2 | chr6 | GO:0099503 | Not Cancer Driver | No | 246 | 0.21 | 319 | 68 | 0.213 | 0 |
| TREML1 | TREML1 | Q86YW5 | Trem-like transcript 1 protein | chr6 | GO:0099503 | Not Cancer Driver | No | 35 | 0.113 | 136 | 19 | 0.14 | 0 |
| UNC13D | UNC13D | Q70J99 | Protein unc-13 homolog D | chr17 | GO:0099503 | Not Cancer Driver | No | 120 | 0.11 | 248 | 30 | 0.121 | 0 |
| VAMP7_ENST00000286448 | VAMP7 | P51809 | Vesicle-associated membrane protein 7 | chrX | GO:0099503 | Not Cancer Driver | No | 38 | 0.173 | 4 | 1 | 0.25 | 0 |
| VAMP8 | VAMP8 | Q9BV40 | Vesicle-associated membrane protein 8 | chr2 | GO:0099503 | Not Cancer Driver | No | 9 | 0.09 | 27 | 0 | 0.0 | 0 |
| VPS33B | VPS33B | Q9H267 | Vacuolar protein sorting-associated protein 33B | chr15 | GO:0099503 | Not Cancer Driver | No | 54 | 0.088 | 17 | 0 | 0.0 | 2 |
| VWF | VWF | P04275 | von Willebrand factor | chr12 | GO:0099503 | Not Cancer Driver | No | 456 | 0.162 | 91 | 16 | 0.176 | 43 |