Total number of protein in "GO:0098794" GO term: 97
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0098794 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| ADGRB3_ENST00000546190 | ADGRB3 | O60242 | Adhesion G protein-coupled receptor B3 | chr6 | GO:0098794 | Not Cancer Driver | No | 558 | 0.367 | 336 | 149 | 0.443 | 0 |
| AGER_ENST00000375076 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:0098794 | Not Cancer Driver | No | 31 | 0.077 | 297 | 21 | 0.071 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0098794 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| AP2B1_ENST00000621914 | AP2B1 | P63010 | AP-2 complex subunit beta | chr17 | GO:0098794 | Not Cancer Driver | No | 85 | 0.091 | 95 | 12 | 0.126 | 0 |
| AP2M1_ENST00000292807 | AP2M1 | Q96CW1 | AP-2 complex subunit mu | chr3 | GO:0098794 | Not Cancer Driver | No | 55 | 0.126 | 41 | 9 | 0.22 | 1 |
| AP3D1_ENST00000345016 | AP3D1 | O14617 | AP-3 complex subunit delta-1 | chr19 | GO:0098794 | Not Cancer Driver | No | 138 | 0.12 | 404 | 59 | 0.146 | 0 |
| APC2_ENST00000233607 | APC2 | O95996 | Adenomatous polyposis coli protein 2 | chr19 | GO:0098794 | Not Cancer Driver | No | 117 | 0.051 | 1725 | 78 | 0.045 | 0 |
| ARHGEF7 | ARHGEF7 | Q14155 | Rho guanine nucleotide exchange factor 7 | chr13 | GO:0098794 | Not Cancer Driver | No | 106 | 0.132 | 301 | 39 | 0.13 | 0 |
| C1QA | C1QA | P02745 | Complement C1q subcomponent subunit A | chr1 | GO:0098794 | Not Cancer Driver | No | 41 | 0.167 | 124 | 16 | 0.129 | 0 |
| C1QB | C1QB | P02746 | Complement C1q subcomponent subunit B | chr1 | GO:0098794 | Not Cancer Driver | No | 46 | 0.182 | 133 | 31 | 0.233 | 1 |
| C1QC | C1QC | P02747 | Complement C1q subcomponent subunit C | chr1 | GO:0098794 | Not Cancer Driver | No | 46 | 0.188 | 134 | 26 | 0.194 | 1 |
| C9orf72 | C9orf72 | Q96LT7 | Guanine nucleotide exchange factor C9orf72 | chr9 | GO:0098794 | Not Cancer Driver | No | 64 | 0.133 | 11 | 0 | 0.0 | 0 |
| CAMK4_ENST00000512453 | CAMK4 | Q16566 | Calcium/calmodulin-dependent protein kinase type IV | chr5 | GO:0098794 | Not Cancer Driver | No | 101 | 0.214 | 127 | 30 | 0.236 | 0 |
| CAPRIN1_ENST00000532820 | CAPRIN1 | Q14444 | Caprin-1 | chr11 | GO:0098794 | Not Cancer Driver | No | 84 | 0.118 | 603 | 72 | 0.119 | 0 |
| CDH1 | CDH1 | P12830 | Cadherin-1 | chr16 | GO:0098794 | Census, Compendium | Yes | 150 | 0.17 | 400 | 82 | 0.205 | 5 |
| CHRNA7_ENST00000306901 | CHRNA7 | P36544 | Neuronal acetylcholine receptor subunit alpha-7 | chr15 | GO:0098794 | Not Cancer Driver | No | 71 | 0.141 | 18 | 4 | 0.222 | 0 |
| CPLX1 | CPLX1 | O14810 | Complexin-1 | chr4 | GO:0098794 | Not Cancer Driver | No | 19 | 0.142 | 134 | 19 | 0.142 | 0 |
| CPLX2_ENST00000515094 | CPLX2 | Q6PUV4 | Complexin-2 | chr5 | GO:0098794 | Not Cancer Driver | No | 27 | 0.201 | 134 | 27 | 0.201 | 0 |
| CPT1C_ENST00000598293 | CPT1C | Q8TCG5 | Carnitine O-palmitoyltransferase 1, brain isoform | chr19 | GO:0098794 | Not Cancer Driver | No | 138 | 0.172 | 93 | 13 | 0.14 | 1 |
| CYP46A1 | CYP46A1 | Q9Y6A2 | Cholesterol 24-hydroxylase | chr14 | GO:0098794 | Not Cancer Driver | No | 92 | 0.184 | 23 | 4 | 0.174 | 0 |
| DGKQ | DGKQ | P52824 | Diacylglycerol kinase theta | chr4 | GO:0098794 | Not Cancer Driver | No | 56 | 0.059 | 264 | 11 | 0.042 | 0 |
| DRD4 | DRD4 | P21917 | D(4) dopamine receptor | chr11 | GO:0098794 | Not Cancer Driver | No | 26 | 0.062 | 109 | 0 | 0.0 | 0 |
| DYNLL2 | DYNLL2 | Q96FJ2 | Dynein light chain 2, cytoplasmic | chr17 | GO:0098794 | Not Cancer Driver | No | 10 | 0.112 | 0 | 0 | 0.0 | 0 |
| EIF4E_ENST00000450253 | EIF4E | P06730 | Eukaryotic translation initiation factor 4E | chr4 | GO:0098794 | Not Cancer Driver | No | 26 | 0.12 | 54 | 6 | 0.111 | 0 |
| ELAVL1 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | GO:0098794 | Not Cancer Driver | No | 69 | 0.212 | 43 | 5 | 0.116 | 0 |
| EPHB2 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:0098794 | Not Cancer Driver | No | 186 | 0.176 | 119 | 17 | 0.143 | 7 |
| ERBIN_ENST00000284037 | ERBIN | Q96RT1 | Erbin | chr5 | GO:0098794 | Not Cancer Driver | No | 167 | 0.118 | 967 | 118 | 0.122 | 0 |
| FMR1 | FMR1 | Q06787 | Synaptic functional regulator FMR1 | chrX | GO:0098794 | Not Cancer Driver | No | 124 | 0.196 | 327 | 70 | 0.214 | 3 |
| FZD9 | FZD9 | O00144 | Frizzled-9 | chr7 | GO:0098794 | Not Cancer Driver | No | 55 | 0.093 | 61 | 0 | 0.0 | 0 |
| GABRA1_ENST00000638112 | GABRA1 | P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | chr5 | GO:0098794 | Not Cancer Driver | No | 175 | 0.384 | 58 | 31 | 0.534 | 6 |
| GABRA2_ENST00000356504 | GABRA2 | P47869 | Gamma-aminobutyric acid receptor subunit alpha-2 | chr4 | GO:0098794 | Not Cancer Driver | No | 194 | 0.43 | 26 | 13 | 0.5 | 5 |
| GABRA3_ENST00000535043 | GABRA3 | P34903 | Gamma-aminobutyric acid receptor subunit alpha-3 | chrX | GO:0098794 | Not Cancer Driver | No | 136 | 0.276 | 47 | 10 | 0.213 | 0 |
| GABRA4 | GABRA4 | P48169 | Gamma-aminobutyric acid receptor subunit alpha-4 | chr4 | GO:0098794 | Not Cancer Driver | No | 191 | 0.345 | 179 | 82 | 0.458 | 0 |
| GABRA5_ENST00000355395 | GABRA5 | P31644 | Gamma-aminobutyric acid receptor subunit alpha-5 | chr15 | GO:0098794 | Not Cancer Driver | No | 146 | 0.316 | 55 | 14 | 0.255 | 3 |
| GABRA6 | GABRA6 | Q16445 | Gamma-aminobutyric acid receptor subunit alpha-6 | chr5 | GO:0098794 | Not Cancer Driver | No | 186 | 0.411 | 7 | 2 | 0.286 | 0 |
| GABRE | GABRE | P78334 | Gamma-aminobutyric acid receptor subunit epsilon | chrX | GO:0098794 | Not Cancer Driver | No | 133 | 0.263 | 73 | 19 | 0.26 | 0 |
| GABRG1 | GABRG1 | Q8N1C3 | Gamma-aminobutyric acid receptor subunit gamma-1 | chr4 | GO:0098794 | Not Cancer Driver | No | 216 | 0.465 | 7 | 3 | 0.429 | 0 |
| GABRG2_ENST00000639213 | GABRG2 | P18507 | Gamma-aminobutyric acid receptor subunit gamma-2 | chr5 | GO:0098794 | Not Cancer Driver | No | 188 | 0.403 | 19 | 13 | 0.684 | 11 |
| GABRG3 | GABRG3 | Q99928 | Gamma-aminobutyric acid receptor subunit gamma-3 | chr15 | GO:0098794 | Not Cancer Driver | No | 137 | 0.293 | 12 | 5 | 0.417 | 0 |
| GHRL_ENST00000457360 | GHRL | Q9UBU3 | Appetite-regulating hormone | chr3 | GO:0098794 | Not Cancer Driver | No | 20 | 0.171 | 52 | 11 | 0.212 | 0 |
| GHSR | GHSR | Q92847 | Growth hormone secretagogue receptor type 1 | chr3 | GO:0098794 | Not Cancer Driver | No | 85 | 0.232 | 4 | 0 | 0.0 | 2 |
| GIT1_ENST00000225394 | GIT1 | Q9Y2X7 | ARF GTPase-activating protein GIT1 | chr17 | GO:0098794 | Not Cancer Driver | No | 67 | 0.088 | 434 | 42 | 0.097 | 0 |
| GRIA2_ENST00000264426 | GRIA2 | P42262 | Glutamate receptor 2 | chr4 | GO:0098794 | Not Cancer Driver | No | 290 | 0.328 | 50 | 16 | 0.32 | 14 |
| GSK3A | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | GO:0098794 | Not Cancer Driver | No | 55 | 0.114 | 180 | 8 | 0.044 | 0 |
| GSK3B_ENST00000264235 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0098794 | Not Cancer Driver | No | 56 | 0.133 | 146 | 13 | 0.089 | 0 |
| HCRT | HCRT | O43612 | Orexin | chr17 | GO:0098794 | Not Cancer Driver | No | 3 | 0.023 | 45 | 0 | 0.0 | 1 |
| HIP1 | HIP1 | O00291 | Huntingtin-interacting protein 1 | chr7 | GO:0098794 | Census, Compendium | Yes | 137 | 0.132 | 510 | 70 | 0.137 | 0 |
| INA | INA | Q16352 | Alpha-internexin | chr10 | GO:0098794 | Not Cancer Driver | No | 62 | 0.124 | 256 | 43 | 0.168 | 0 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0098794 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0098794 | Not Cancer Driver | No | 519 | 0.205 | 90 | 17 | 0.189 | 23 |
| MECP2_ENST00000303391 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | GO:0098794 | Not Cancer Driver | No | 75 | 0.154 | 483 | 74 | 0.153 | 46 |
| MEF2C_ENST00000504921 | MEF2C | Q06413 | Myocyte-specific enhancer factor 2C | chr5 | GO:0098794 | Not Cancer Driver | No | 92 | 0.195 | 408 | 81 | 0.199 | 0 |
| METTL5 | METTL5 | Q9NRN9 | rRNA N6-adenosine-methyltransferase METTL5 | chr2 | GO:0098794 | Not Cancer Driver | No | 19 | 0.091 | 0 | 0 | 0.0 | 0 |
| MKLN1 | MKLN1 | Q9UL63 | Muskelin | chr7 | GO:0098794 | Not Cancer Driver | No | 85 | 0.116 | 91 | 13 | 0.143 | 0 |
| NCDN_ENST00000356090 | NCDN | Q9UBB6 | Neurochondrin | chr1 | GO:0098794 | Not Cancer Driver | No | 77 | 0.106 | 21 | 5 | 0.238 | 3 |
| NLGN1_ENST00000361589 | NLGN1 | Q8N2Q7 | Neuroligin-1 | chr3 | GO:0098794 | Not Cancer Driver | No | 214 | 0.248 | 248 | 61 | 0.246 | 4 |
| NPAS4 | NPAS4 | Q8IUM7 | Neuronal PAS domain-containing protein 4 | chr11 | GO:0098794 | Not Cancer Driver | No | 229 | 0.286 | 429 | 114 | 0.266 | 0 |
| NPFF | NPFF | O15130 | Pro-FMRFamide-related neuropeptide FF | chr12 | GO:0098794 | Not Cancer Driver | No | 16 | 0.142 | 64 | 7 | 0.109 | 0 |
| P2RX2_ENST00000643471 | P2RX2 | Q9UBL9 | P2X purinoceptor 2 | chr12 | GO:0098794 | Not Cancer Driver | No | 62 | 0.132 | 104 | 13 | 0.125 | 2 |
| P2RX5 | P2RX5 | Q93086 | P2X purinoceptor 5 | chr17 | GO:0098794 | Not Cancer Driver | No | 58 | 0.137 | 73 | 14 | 0.192 | 0 |
| P2RX7 | P2RX7 | Q99572 | P2X purinoceptor 7 | chr12 | GO:0098794 | Not Cancer Driver | No | 51 | 0.086 | 14 | 2 | 0.143 | 0 |
| PFN2 | PFN2 | P35080 | Profilin-2 | chr3 | GO:0098794 | Not Cancer Driver | No | 20 | 0.143 | 0 | 0 | 0.0 | 0 |
| PLAT | PLAT | P00750 | Tissue-type plasminogen activator | chr8 | GO:0098794 | Not Cancer Driver | No | 89 | 0.158 | 15 | 2 | 0.133 | 0 |
| PLCB1 | PLCB1 | Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | chr20 | GO:0098794 | Not Cancer Driver | No | 313 | 0.257 | 481 | 104 | 0.216 | 0 |
| PRNP | PRNP | P04156 | Major prion protein | chr20 | GO:0098794 | Not Cancer Driver | No | 36 | 0.142 | 115 | 7 | 0.061 | 18 |
| PSD2 | PSD2 | Q9BQI7 | PH and SEC7 domain-containing protein 2 | chr5 | GO:0098794 | Not Cancer Driver | No | 155 | 0.201 | 398 | 87 | 0.219 | 0 |
| PSMA7 | PSMA7 | O14818 | Proteasome subunit alpha type-7 | chr20 | GO:0098794 | Not Cancer Driver | No | 24 | 0.097 | 23 | 1 | 0.043 | 0 |
| PSMC5 | PSMC5 | P62195 | 26S proteasome regulatory subunit 8 | chr17 | GO:0098794 | Not Cancer Driver | No | 52 | 0.128 | 64 | 6 | 0.094 | 0 |
| PURA | PURA | Q00577 | Transcriptional activator protein Pur-alpha | chr5 | GO:0098794 | Not Cancer Driver | No | 22 | 0.068 | 188 | 10 | 0.053 | 6 |
| RAB3A | RAB3A | P20336 | Ras-related protein Rab-3A | chr19 | GO:0098794 | Not Cancer Driver | No | 25 | 0.114 | 43 | 4 | 0.093 | 0 |
| RAB3GAP1_ENST00000264158 | RAB3GAP1 | Q15042 | Rab3 GTPase-activating protein catalytic subunit | chr2 | GO:0098794 | Not Cancer Driver | No | 123 | 0.125 | 294 | 32 | 0.109 | 2 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | GO:0098794 | Census, Compendium | Yes | 66 | 0.344 | 2 | 1 | 0.5 | 6 |
| RGS7BP | RGS7BP | Q6MZT1 | Regulator of G-protein signaling 7-binding protein | chr5 | GO:0098794 | Not Cancer Driver | No | 49 | 0.191 | 166 | 31 | 0.187 | 0 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0098794 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
| RNF19A | RNF19A | Q9NV58 | E3 ubiquitin-protein ligase RNF19A | chr8 | GO:0098794 | Not Cancer Driver | No | 112 | 0.134 | 387 | 55 | 0.142 | 0 |
| RPL8_ENST00000528957 | RPL8 | P62917 | 60S ribosomal protein L8 | chr8 | GO:0098794 | Not Cancer Driver | No | 32 | 0.125 | 115 | 17 | 0.148 | 0 |
| RPLP0_ENST00000228306 | RPLP0 | P05388 | 60S acidic ribosomal protein P0 | chr12 | GO:0098794 | Not Cancer Driver | No | 44 | 0.139 | 36 | 4 | 0.111 | 0 |
| SLC29A1_ENST00000371708 | SLC29A1 | Q99808 | Equilibrative nucleoside transporter 1 | chr6 | GO:0098794 | Not Cancer Driver | No | 51 | 0.112 | 27 | 4 | 0.148 | 0 |
| SLC4A10 | SLC4A10 | Q6U841 | Sodium-driven chloride bicarbonate exchanger | chr2 | GO:0098794 | Not Cancer Driver | No | 221 | 0.198 | 340 | 68 | 0.2 | 0 |
| SLC6A17 | SLC6A17 | Q9H1V8 | Sodium-dependent neutral amino acid transporter SLC6A17 | chr1 | GO:0098794 | Not Cancer Driver | No | 119 | 0.164 | 67 | 10 | 0.149 | 2 |
| SLC8A1_ENST00000332839 | SLC8A1 | P32418 | Sodium/calcium exchanger 1 | chr2 | GO:0098794 | Not Cancer Driver | No | 305 | 0.313 | 158 | 48 | 0.304 | 0 |
| SLC8A2 | SLC8A2 | Q9UPR5 | Sodium/calcium exchanger 2 | chr19 | GO:0098794 | Not Cancer Driver | No | 117 | 0.127 | 143 | 19 | 0.133 | 0 |
| SLC8A3 | SLC8A3 | P57103 | Sodium/calcium exchanger 3 | chr14 | GO:0098794 | Not Cancer Driver | No | 263 | 0.284 | 152 | 35 | 0.23 | 0 |
| SMCR8 | SMCR8 | Q8TEV9 | Guanine nucleotide exchange protein SMCR8 | chr17 | GO:0098794 | Not Cancer Driver | No | 107 | 0.114 | 357 | 38 | 0.106 | 0 |
| SNAP25 | SNAP25 | P60880 | Synaptosomal-associated protein 25 | chr20 | GO:0098794 | Not Cancer Driver | No | 61 | 0.296 | 176 | 49 | 0.278 | 1 |
| SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0098794 | Not Cancer Driver | No | 21 | 0.15 | 107 | 13 | 0.121 | 5 |
| STX3 | STX3 | Q13277 | Syntaxin-3 | chr11 | GO:0098794 | Not Cancer Driver | No | 51 | 0.176 | 129 | 30 | 0.233 | 0 |
| STX4 | STX4 | Q12846 | Syntaxin-4 | chr16 | GO:0098794 | Not Cancer Driver | No | 50 | 0.168 | 152 | 20 | 0.132 | 0 |
| STXBP1_ENST00000373299 | STXBP1 | P61764 | Syntaxin-binding protein 1 | chr9 | GO:0098794 | Not Cancer Driver | No | 97 | 0.163 | 111 | 23 | 0.207 | 18 |
| TNS2_ENST00000314250 | TNS2 | Q63HR2 | Tensin-2 | chr12 | GO:0098794 | Not Cancer Driver | No | 132 | 0.094 | 799 | 63 | 0.079 | 0 |
| WASF1_ENST00000392586 | WASF1 | Q92558 | Wiskott-Aldrich syndrome protein family member 1 | chr6 | GO:0098794 | Not Cancer Driver | No | 63 | 0.113 | 445 | 49 | 0.11 | 0 |
| WASF3 | WASF3 | Q9UPY6 | Wiskott-Aldrich syndrome protein family member 3 | chr13 | GO:0098794 | Not Cancer Driver | No | 108 | 0.215 | 386 | 84 | 0.218 | 0 |
| WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0098794 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
| ZDHHC15 | ZDHHC15 | Q96MV8 | Palmitoyltransferase ZDHHC15 | chrX | GO:0098794 | Not Cancer Driver | No | 81 | 0.24 | 45 | 9 | 0.2 | 0 |
| ZNF804A | ZNF804A | Q7Z570 | Zinc finger protein 804A | chr2 | GO:0098794 | Not Cancer Driver | No | 506 | 0.419 | 687 | 307 | 0.447 | 0 |
| ZZEF1 | ZZEF1 | O43149 | Zinc finger ZZ-type and EF-hand domain-containing protein 1 | chr17 | GO:0098794 | Not Cancer Driver | No | 292 | 0.099 | 580 | 69 | 0.119 | 0 |