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Total number of protein in "GO:0098793" GO term:  130

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0098793 Not Cancer Driver No 112 0.299 43 5 0.116 5
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 GO:0098793 Not Cancer Driver No 73 0.195 42 10 0.238 16
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0098793 Not Cancer Driver No 64 0.196 12 4 0.333 0
AP2M1_ENST00000292807 AP2M1 Q96CW1 AP-2 complex subunit mu chr3 GO:0098793 Not Cancer Driver No 55 0.126 41 9 0.22 1
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 GO:0098793 Not Cancer Driver No 18 0.103 5 0 0.0 0
ATCAY ATCAY Q86WG3 Caytaxin chr19 GO:0098793 Not Cancer Driver No 75 0.202 188 38 0.202 1
BAIAP3 BAIAP3 O94812 BAI1-associated protein 3 chr16 GO:0098793 Not Cancer Driver No 170 0.143 230 35 0.152 0
BLOC1S6_ENST00000220531 BLOC1S6 Q9UL45 Biogenesis of lysosome-related organelles complex 1 subunit 6 chr15 GO:0098793 Not Cancer Driver No 12 0.07 111 11 0.099 0
C1QL1 C1QL1 O75973 C1q-related factor chr17 GO:0098793 Not Cancer Driver No 25 0.097 126 5 0.04 0
C9orf72 C9orf72 Q96LT7 Guanine nucleotide exchange factor C9orf72 chr9 GO:0098793 Not Cancer Driver No 64 0.133 11 0 0.0 0
CACNB2 CACNB2 Q08289 Voltage-dependent L-type calcium channel subunit beta-2 chr10 GO:0098793 Not Cancer Driver No 155 0.235 478 106 0.222 0
CADPS CADPS Q9ULU8 Calcium-dependent secretion activator 1 chr3 GO:0098793 Not Cancer Driver No 298 0.22 336 71 0.211 0
CADPS2 CADPS2 Q86UW7 Calcium-dependent secretion activator 2 chr7 GO:0098793 Not Cancer Driver No 194 0.15 202 22 0.109 0
CALB1 CALB1 P05937 Calbindin chr8 GO:0098793 Not Cancer Driver No 46 0.176 0 0 0.0 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0098793 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0098793 Not Cancer Driver No 35 0.114 103 16 0.155 0
CEL CEL P19835 Bile salt-activated lipase chr9 GO:0098793 Not Cancer Driver No 101 0.134 280 40 0.143 0
CLN8 CLN8 Q9UBY8 Protein CLN8 chr8 GO:0098793 Not Cancer Driver No 45 0.157 16 2 0.125 16
CPLX1 CPLX1 O14810 Complexin-1 chr4 GO:0098793 Not Cancer Driver No 19 0.142 134 19 0.142 0
CPLX2_ENST00000515094 CPLX2 Q6PUV4 Complexin-2 chr5 GO:0098793 Not Cancer Driver No 27 0.201 134 27 0.201 0
CYP46A1 CYP46A1 Q9Y6A2 Cholesterol 24-hydroxylase chr14 GO:0098793 Not Cancer Driver No 92 0.184 23 4 0.174 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0098793 Not Cancer Driver No 56 0.059 264 11 0.042 0
DNAJC5 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 GO:0098793 Not Cancer Driver No 23 0.116 46 6 0.13 1
DNAJC6_ENST00000395325 DNAJC6 O75061 Putative tyrosine-protein phosphatase auxilin chr1 GO:0098793 Not Cancer Driver No 165 0.181 455 82 0.18 1
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0098793 Census Yes 138 0.159 270 43 0.159 22
DNM3_ENST00000355305 DNM3 Q9UQ16 Dynamin-3 chr1 GO:0098793 Not Cancer Driver No 166 0.191 257 45 0.175 0
DNMBP DNMBP Q6XZF7 Dynamin-binding protein chr10 GO:0098793 Not Cancer Driver No 208 0.132 758 92 0.121 0
DOC2B DOC2B Q14184 Double C2-like domain-containing protein beta chr17 GO:0098793 Not Cancer Driver No 10 0.024 197 3 0.015 0
DVL1 DVL1 O14640 Segment polarity protein dishevelled homolog DVL-1 chr1 GO:0098793 Not Cancer Driver No 73 0.105 434 38 0.088 0
FBXL20 FBXL20 Q96IG2 F-box/LRR-repeat protein 20 chr17 GO:0098793 Not Cancer Driver No 48 0.11 1 0 0.0 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0098793 Not Cancer Driver No 124 0.196 327 70 0.214 3
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 GO:0098793 Not Cancer Driver No 88 0.142 312 53 0.17 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 GO:0098793 Not Cancer Driver No 68 0.101 388 42 0.108 0
GAK GAK O14976 Cyclin-G-associated kinase chr4 GO:0098793 Not Cancer Driver No 146 0.111 589 79 0.134 0
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 GO:0098793 Not Cancer Driver No 67 0.088 434 42 0.097 0
GNB5 GNB5 O14775 Guanine nucleotide-binding protein subunit beta-5 chr15 GO:0098793 Not Cancer Driver No 60 0.152 16 1 0.062 1
GRAP GRAP Q13588 GRB2-related adapter protein chr17 GO:0098793 Not Cancer Driver No 10 0.046 0 0 0.0 1
GRIA1_ENST00000285900 GRIA1 P42261 Glutamate receptor 1 chr5 GO:0098793 Not Cancer Driver No 303 0.334 104 45 0.433 0
GRM4 GRM4 Q14833 Metabotropic glutamate receptor 4 chr6 GO:0098793 Not Cancer Driver No 187 0.205 74 22 0.297 0
HCN3 HCN3 Q9P1Z3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 chr1 GO:0098793 Not Cancer Driver No 107 0.138 260 22 0.085 0
HIP1 HIP1 O00291 Huntingtin-interacting protein 1 chr7 GO:0098793 Census, Compendium Yes 137 0.132 510 70 0.137 0
HRH3 HRH3 Q9Y5N1 Histamine H3 receptor chr20 GO:0098793 Not Cancer Driver No 65 0.146 93 10 0.108 0
HTR1B HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 GO:0098793 Not Cancer Driver No 91 0.233 33 15 0.455 0
ITSN1 ITSN1 Q15811 Intersectin-1 chr21 GO:0098793 Not Cancer Driver No 214 0.124 797 107 0.134 0
ITSN2 ITSN2 Q9NZM3 Intersectin-2 chr2 GO:0098793 Not Cancer Driver No 207 0.122 680 92 0.135 0
KCNA1 KCNA1 Q09470 Potassium voltage-gated channel subfamily A member 1 chr12 GO:0098793 Not Cancer Driver No 176 0.356 69 34 0.493 17
KCNA2_ENST00000638616 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 GO:0098793 Not Cancer Driver No 96 0.192 82 16 0.195 5
KCNA3 KCNA3 P22001 Potassium voltage-gated channel subfamily A member 3 chr1 GO:0098793 Not Cancer Driver No 120 0.209 169 16 0.095 0
KCNC1_ENST00000379472 KCNC1 P48547 Potassium voltage-gated channel subfamily C member 1 chr11 GO:0098793 Not Cancer Driver No 91 0.178 110 18 0.164 1
KCNJ10 KCNJ10 P78508 ATP-sensitive inward rectifier potassium channel 10 chr1 GO:0098793 Not Cancer Driver No 78 0.206 28 10 0.357 8
KCNK2 KCNK2 O95069 Potassium channel subfamily K member 2 chr1 GO:0098793 Not Cancer Driver No 109 0.256 40 10 0.25 0
KIAA1109 KIAA1109 Q2LD37 Transmembrane protein KIAA1109 chr4 GO:0098793 Not Cancer Driver No 688 0.137 2276 312 0.137 0
LIN7A LIN7A O14910 Protein lin-7 homolog A chr12 GO:0098793 Not Cancer Driver No 76 0.326 127 29 0.228 0
LIN7B LIN7B Q9HAP6 Protein lin-7 homolog B chr19 GO:0098793 Not Cancer Driver No 26 0.126 107 16 0.15 0
LIN7C LIN7C Q9NUP9 Protein lin-7 homolog C chr11 GO:0098793 Not Cancer Driver No 22 0.112 102 11 0.108 0
METTL5 METTL5 Q9NRN9 rRNA N6-adenosine-methyltransferase METTL5 chr2 GO:0098793 Not Cancer Driver No 19 0.091 0 0 0.0 0
MICAL1_ENST00000358807 MICAL1 Q8TDZ2 [F-actin]-monooxygenase MICAL1 chr6 GO:0098793 Not Cancer Driver No 112 0.105 364 37 0.102 0
MME_ENST00000492661 MME P08473 Neprilysin chr3 GO:0098793 Not Cancer Driver No 189 0.252 40 17 0.425 4
NAPA NAPA P54920 Alpha-soluble NSF attachment protein chr19 GO:0098793 Not Cancer Driver No 33 0.112 11 0 0.0 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0098793 Census, Compendium Yes 375 0.132 406 47 0.116 85
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0098793 Not Cancer Driver No 214 0.248 248 61 0.246 4
NLGN3 NLGN3 Q9NZ94 Neuroligin-3 chrX GO:0098793 Not Cancer Driver No 158 0.186 257 54 0.21 2
NLGN4X_ENST00000381093 NLGN4X Q8N0W4 Neuroligin-4, X-linked chrX GO:0098793 Not Cancer Driver No 279 0.342 211 81 0.384 0
NLGN4Y NLGN4Y Q8NFZ3 Neuroligin-4, Y-linked chrY GO:0098793 Not Cancer Driver No 94 0.115 206 26 0.126 0
NOSTRIN_ENST00000317647 NOSTRIN Q8IVI9 Nostrin chr2 GO:0098793 Not Cancer Driver No 55 0.109 190 18 0.095 0
NR4A1_ENST00000394825 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 GO:0098793 Not Cancer Driver No 62 0.104 252 24 0.095 0
NRXN2_ENST00000377551 NRXN2 Q9P2S2 Neurexin-2 chr11 GO:0098793 Not Cancer Driver No 278 0.162 547 80 0.146 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0098793 Not Cancer Driver No 51 0.086 14 2 0.143 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0098793 Not Cancer Driver No 11 0.058 30 0 0.0 5
PDLIM5_ENST00000317968 PDLIM5 Q96HC4 PDZ and LIM domain protein 5 chr4 GO:0098793 Not Cancer Driver No 89 0.149 372 57 0.153 0
PDZD11_ENST00000374454 PDZD11 Q5EBL8 PDZ domain-containing protein 11 chrX GO:0098793 Not Cancer Driver No 20 0.143 46 8 0.174 0
PFN2 PFN2 P35080 Profilin-2 chr3 GO:0098793 Not Cancer Driver No 20 0.143 0 0 0.0 0
PIP5K1C_ENST00000335312 PIP5K1C O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma chr19 GO:0098793 Not Cancer Driver No 98 0.147 360 60 0.167 1
PLD2 PLD2 O14939 Phospholipase D2 chr17 GO:0098793 Not Cancer Driver No 107 0.115 97 8 0.082 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 GO:0098793 Not Cancer Driver No 38 0.115 27 6 0.222 0
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 GO:0098793 Not Cancer Driver No 26 0.08 23 4 0.174 0
PPP3CC_ENST00000240139 PPP3CC P48454 Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform chr8 GO:0098793 Not Cancer Driver No 47 0.092 91 7 0.077 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0098793 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0098793 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0098793 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRRT2_ENST00000645336 PRRT2 Q7Z6L0 Proline-rich transmembrane protein 2 chr16 GO:0098793 Not Cancer Driver No 45 0.132 268 32 0.119 7
RAB33B RAB33B Q9H082 Ras-related protein Rab-33B chr4 GO:0098793 Not Cancer Driver No 22 0.096 30 3 0.1 2
RAB3A RAB3A P20336 Ras-related protein Rab-3A chr19 GO:0098793 Not Cancer Driver No 25 0.114 43 4 0.093 0
RAB6B RAB6B Q9NRW1 Ras-related protein Rab-6B chr3 GO:0098793 Not Cancer Driver No 39 0.188 42 5 0.119 0
RPL22 RPL22 P35268 60S ribosomal protein L22 chr1 GO:0098793 Census, Compendium Yes 26 0.203 15 1 0.067 0
RTN4R RTN4R Q9BZR6 Reticulon-4 receptor chr22 GO:0098793 Not Cancer Driver No 38 0.08 148 17 0.115 5
SEPT3 SEPTIN3 Q9UH03 Neuronal-specific septin-3 chr22 GO:0098793 Not Cancer Driver No 51 0.142 105 13 0.124 0
SEPT8 SEPTIN8 Q92599 Septin-8 chr5 GO:0098793 Not Cancer Driver No 52 0.108 172 17 0.099 0
SH3GL1 SH3GL1 Q99961 Endophilin-A2 chr19 GO:0098793 Census Yes 45 0.122 245 33 0.135 0
SH3GL2 SH3GL2 Q99962 Endophilin-A1 chr9 GO:0098793 Not Cancer Driver No 76 0.216 214 50 0.234 0
SH3GL3_ENST00000427482 SH3GL3 Q99963 Endophilin-A3 chr15 GO:0098793 Not Cancer Driver No 88 0.254 83 23 0.277 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0098793 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC1A7_ENST00000371494 SLC1A7 O00341 Excitatory amino acid transporter 5 chr1 GO:0098793 Not Cancer Driver No 85 0.152 43 8 0.186 0
SLC22A1 SLC22A1 O15245 Solute carrier family 22 member 1 chr6 GO:0098793 Not Cancer Driver No 68 0.123 12 0 0.0 0
SLC22A2 SLC22A2 O15244 Solute carrier family 22 member 2 chr6 GO:0098793 Not Cancer Driver No 126 0.227 31 11 0.355 0
SLC22A3 SLC22A3 O75751 Solute carrier family 22 member 3 chr6 GO:0098793 Not Cancer Driver No 73 0.131 21 1 0.048 0
SLC29A1_ENST00000371708 SLC29A1 Q99808 Equilibrative nucleoside transporter 1 chr6 GO:0098793 Not Cancer Driver No 51 0.112 27 4 0.148 0
SLC29A2_ENST00000544554 SLC29A2 Q14542 Equilibrative nucleoside transporter 2 chr11 GO:0098793 Not Cancer Driver No 60 0.132 30 6 0.2 0
SLC29A4_ENST00000297195 SLC29A4 Q7RTT9 Equilibrative nucleoside transporter 4 chr7 GO:0098793 Not Cancer Driver No 93 0.175 49 10 0.204 0
SLC2A1 SLC2A1 P11166 Solute carrier family 2, facilitated glucose transporter member 1 chr1 GO:0098793 Not Cancer Driver No 51 0.104 13 2 0.154 48
SLC2A4 SLC2A4 P14672 Solute carrier family 2, facilitated glucose transporter member 4 chr17 GO:0098793 Not Cancer Driver No 71 0.139 43 8 0.186 1
SLC32A1 SLC32A1 Q9H598 Vesicular inhibitory amino acid transporter chr20 GO:0098793 Not Cancer Driver No 138 0.263 82 19 0.232 0
SLC4A8 SLC4A8 Q2Y0W8 Electroneutral sodium bicarbonate exchanger 1 chr12 GO:0098793 Not Cancer Driver No 176 0.161 276 41 0.149 0
SLC6A12_ENST00000536824 SLC6A12 P48065 Sodium- and chloride-dependent betaine transporter chr12 GO:0098793 Not Cancer Driver No 94 0.153 45 8 0.178 0
SLC6A13 SLC6A13 Q9NSD5 Sodium- and chloride-dependent GABA transporter 2 chr12 GO:0098793 Not Cancer Driver No 136 0.226 37 11 0.297 0
SLC8A2 SLC8A2 Q9UPR5 Sodium/calcium exchanger 2 chr19 GO:0098793 Not Cancer Driver No 117 0.127 143 19 0.133 0
SMCR8 SMCR8 Q8TEV9 Guanine nucleotide exchange protein SMCR8 chr17 GO:0098793 Not Cancer Driver No 107 0.114 357 38 0.106 0
SNAP23 SNAP23 O00161 Synaptosomal-associated protein 23 chr15 GO:0098793 Not Cancer Driver No 18 0.085 179 16 0.089 0
SNAP29 SNAP29 O95721 Synaptosomal-associated protein 29 chr22 GO:0098793 Not Cancer Driver No 21 0.081 246 20 0.081 0
SNAP47_ENST00000366759 SNAP47 Q5SQN1 Synaptosomal-associated protein 47 chr1 GO:0098793 Not Cancer Driver No 51 0.11 192 20 0.104 0
SNPH_ENST00000381873 SNPH O15079 Syntaphilin chr20 GO:0098793 Not Cancer Driver No 79 0.16 406 71 0.175 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0098793 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPTBN2 SPTBN2 O15020 Spectrin beta chain, non-erythrocytic 2 chr11 GO:0098793 Not Cancer Driver No 317 0.133 877 126 0.144 2
STXBP2_ENST00000221283 STXBP2 Q15833 Syntaxin-binding protein 2 chr19 GO:0098793 Not Cancer Driver No 77 0.13 80 13 0.163 5
STXBP3 STXBP3 O00186 Syntaxin-binding protein 3 chr1 GO:0098793 Not Cancer Driver No 59 0.1 64 9 0.141 0
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 GO:0098793 Not Cancer Driver No 208 0.132 584 76 0.13 3
SYNJ2 SYNJ2 O15056 Synaptojanin-2 chr6 GO:0098793 Not Cancer Driver No 189 0.126 545 70 0.128 0
SYT11 SYT11 Q9BT88 Synaptotagmin-11 chr1 GO:0098793 Not Cancer Driver No 64 0.148 105 23 0.219 0
TNIK TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 GO:0098793 Not Cancer Driver No 254 0.187 781 156 0.2 0
TNN TNN Q9UQP3 Tenascin-N chr1 GO:0098793 Not Cancer Driver No 426 0.328 637 231 0.363 0
TPRG1L TPRG1L Q5T0D9 Tumor protein p63-regulated gene 1-like protein chr1 GO:0098793 Not Cancer Driver No 25 0.092 52 0 0.0 0
TSPOAP1 TSPOAP1 O95153 Peripheral-type benzodiazepine receptor-associated protein 1 chr17 GO:0098793 Not Cancer Driver No 268 0.144 1522 213 0.14 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0098793 Not Cancer Driver No 19 0.123 32 4 0.125 0
UNC13C UNC13C Q8NB66 Protein unc-13 homolog C chr15 GO:0098793 Not Cancer Driver No 681 0.308 886 268 0.302 0
VPS18 VPS18 Q9P253 Vacuolar protein sorting-associated protein 18 homolog chr15 GO:0098793 Not Cancer Driver No 96 0.099 86 7 0.081 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0098793 Not Cancer Driver No 68 0.085 99 9 0.091 1
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0098793 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0098793 Not Cancer Driver No 93 0.266 18 9 0.5 4
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 GO:0098793 Not Cancer Driver No 26 0.105 77 9 0.117 2
ZNF804A ZNF804A Q7Z570 Zinc finger protein 804A chr2 GO:0098793 Not Cancer Driver No 506 0.419 687 307 0.447 0