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Total number of protein in "GO:0098590" GO term:  393

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCC1 ABCC1 P33527 Multidrug resistance-associated protein 1 chr16 GO:0098590 Not Cancer Driver No 199 0.13 123 22 0.179 1
ABCG2 ABCG2 Q9UNQ0 Broad substrate specificity ATP-binding cassette transporter ABCG2 chr4 GO:0098590 Not Cancer Driver No 124 0.189 35 10 0.286 0
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0098590 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:0098590 Not Cancer Driver No 104 0.129 68 5 0.074 0
ADAM21 ADAM21 Q9UKJ8 Disintegrin and metalloproteinase domain-containing protein 21 chr14 GO:0098590 Not Cancer Driver No 167 0.231 4 1 0.25 0
ADAM29_ENST00000404450 ADAM29 Q9UKF5 Disintegrin and metalloproteinase domain-containing protein 29 chr4 GO:0098590 Not Cancer Driver No 257 0.313 124 39 0.315 0
ADAM30 ADAM30 Q9UKF2 Disintegrin and metalloproteinase domain-containing protein 30 chr1 GO:0098590 Not Cancer Driver No 133 0.168 73 12 0.164 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0098590 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADCYAP1R1_ENST00000304166 ADCYAP1R1 P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor chr7 GO:0098590 Not Cancer Driver No 127 0.271 0 0 0.0 0
ADGRV1_ENST00000645211 ADGRV1 Q8WXG9 Adhesion G-protein coupled receptor V1 chr5 GO:0098590 Not Cancer Driver No 1124 0.178 496 77 0.155 2
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0098590 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0098590 Not Cancer Driver No 61 0.148 93 11 0.118 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0098590 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRA1B ADRA1B P35368 Alpha-1B adrenergic receptor chr5 GO:0098590 Not Cancer Driver No 53 0.102 132 1 0.008 0
ADTRP_ENST00000414691 ADTRP Q96IZ2 Androgen-dependent TFPI-regulating protein chr6 GO:0098590 Not Cancer Driver No 41 0.178 2 0 0.0 0
AKAP5_ENST00000320636 AKAP5 P24588 A-kinase anchor protein 5 chr14 GO:0098590 Not Cancer Driver No 37 0.087 405 34 0.084 0
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0098590 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AMN AMN Q9BXJ7 Protein amnionless chr14 GO:0098590 Not Cancer Driver No 27 0.06 6 0 0.0 3
ANK3 ANK3 Q12955 Ankyrin-3 chr10 GO:0098590 Not Cancer Driver No 860 0.196 3054 579 0.19 0
ANKRD45 ANKRD45 Q5TZF3 Ankyrin repeat domain-containing protein 45 chr1 GO:0098590 Not Cancer Driver No 60 0.226 101 22 0.218 0
ANTXR1 ANTXR1 Q9H6X2 Anthrax toxin receptor 1 chr2 GO:0098590 Not Cancer Driver No 105 0.186 183 44 0.24 0
APBA1 APBA1 Q02410 Amyloid-beta A4 precursor protein-binding family A member 1 chr9 GO:0098590 Not Cancer Driver No 149 0.178 556 103 0.185 0
APC2_ENST00000233607 APC2 O95996 Adenomatous polyposis coli protein 2 chr19 GO:0098590 Not Cancer Driver No 117 0.051 1725 78 0.045 0
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0098590 Not Cancer Driver No 39 0.145 4 1 0.25 0
AQP5 AQP5 P55064 Aquaporin-5 chr12 GO:0098590 Not Cancer Driver No 31 0.117 21 2 0.095 5
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 GO:0098590 Not Cancer Driver No 18 0.103 5 0 0.0 0
ARPC2_ENST00000315717 ARPC2 O15144 Actin-related protein 2/3 complex subunit 2 chr2 GO:0098590 Not Cancer Driver No 40 0.133 49 8 0.163 0
ASAH2 ASAH2 Q9NR71 Neutral ceramidase chr10 GO:0098590 Not Cancer Driver No 71 0.091 140 24 0.171 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0098590 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATP1A1_ENST00000295598 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 GO:0098590 Census Yes 115 0.112 115 16 0.139 6
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0098590 Not Cancer Driver No 230 0.225 161 34 0.211 8
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 GO:0098590 Not Cancer Driver No 200 0.197 115 29 0.252 31
ATP1B1 ATP1B1 P05026 Sodium/potassium-transporting ATPase subunit beta-1 chr1 GO:0098590 Not Cancer Driver No 38 0.125 55 9 0.164 0
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0098590 Not Cancer Driver No 143 0.117 293 42 0.143 0
ATP2B2 ATP2B2 Q01814 Plasma membrane calcium-transporting ATPase 2 chr3 GO:0098590 Not Cancer Driver No 248 0.2 360 82 0.228 0
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX GO:0098590 Not Cancer Driver No 56 0.16 0 0 0.0 2
ATP6V0A4 ATP6V0A4 Q9HBG4 V-type proton ATPase 116 kDa subunit a 4 chr7 GO:0098590 Not Cancer Driver No 148 0.176 43 6 0.14 6
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0098590 Not Cancer Driver No 228 0.152 171 46 0.269 52
B4GALT1 B4GALT1 P15291 Beta-1,4-galactosyltransferase 1 chr9 GO:0098590 Not Cancer Driver No 38 0.095 129 13 0.101 0
BEST1_ENST00000378043 BEST1 O76090 Bestrophin-1 chr11 GO:0098590 Not Cancer Driver No 47 0.08 229 18 0.079 108
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0098590 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0098590 Compendium Yes 141 0.136 601 70 0.116 19
BVES BVES Q8NE79 Blood vessel epicardial substance chr6 GO:0098590 Not Cancer Driver No 59 0.164 65 15 0.231 1
C5AR2_ENST00000600626 C5AR2 Q9P296 C5a anaphylatoxin chemotactic receptor 2 chr19 GO:0098590 Not Cancer Driver No 60 0.178 11 3 0.273 0
CA4 CA4 P22748 Carbonic anhydrase 4 chr17 GO:0098590 Not Cancer Driver No 55 0.176 81 12 0.148 4
CA9 CA9 Q16790 Carbonic anhydrase 9 chr9 GO:0098590 Not Cancer Driver No 72 0.157 274 50 0.182 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0098590 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV2 CAV2 P51636 Caveolin-2 chr7 GO:0098590 Not Cancer Driver No 20 0.123 5 2 0.4 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0098590 Not Cancer Driver No 27 0.179 0 0 0.0 25
CAVIN1 CAVIN1 Q6NZI2 Caveolae-associated protein 1 chr17 GO:0098590 Not Cancer Driver No 66 0.169 280 50 0.179 0
CAVIN2 CAVIN2 O95810 Caveolae-associated protein 2 chr2 GO:0098590 Not Cancer Driver No 109 0.256 393 99 0.252 0
CAVIN3 CAVIN3 Q969G5 Caveolae-associated protein 3 chr11 GO:0098590 Not Cancer Driver No 22 0.084 234 19 0.081 0
CAVIN4 CAVIN4 Q5BKX8 Caveolae-associated protein 4 chr9 GO:0098590 Not Cancer Driver No 59 0.162 286 45 0.157 0
CD34 CD34 P28906 Hematopoietic progenitor cell antigen CD34 chr1 GO:0098590 Not Cancer Driver No 65 0.169 221 34 0.154 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0098590 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD44 CD44 P16070 CD44 antigen chr11 GO:0098590 Not Cancer Driver No 75 0.101 542 60 0.111 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0098590 Not Cancer Driver No 28 0.119 0 0 0.0 0
CDH13_ENST00000567109 CDH13 P55290 Cadherin-13 chr16 GO:0098590 Not Cancer Driver No 168 0.236 235 59 0.251 0
CDH15 CDH15 P55291 Cadherin-15 chr16 GO:0098590 Not Cancer Driver No 105 0.129 405 57 0.141 3
CDH2 CDH2 P19022 Cadherin-2 chr18 GO:0098590 Not Cancer Driver No 238 0.263 461 130 0.282 7
CDHR1 CDHR1 Q96JP9 Cadherin-related family member 1 chr10 GO:0098590 Not Cancer Driver No 149 0.173 277 42 0.152 1
CDHR2 CDHR2 Q9BYE9 Cadherin-related family member 2 chr5 GO:0098590 Not Cancer Driver No 237 0.181 251 52 0.207 0
CDHR5 CDHR5 Q9HBB8 Cadherin-related family member 5 chr11 GO:0098590 Not Cancer Driver No 112 0.133 503 70 0.139 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0098590 Not Cancer Driver No 64 0.122 241 25 0.104 0
CEACAM20 CEACAM20 Q6UY09 Carcinoembryonic antigen-related cell adhesion molecule 20 chr19 GO:0098590 Not Cancer Driver No 86 0.144 182 30 0.165 0
CEP55 CEP55 Q53EZ4 Centrosomal protein of 55 kDa chr10 GO:0098590 Not Cancer Driver No 59 0.127 264 26 0.098 0
CFL1_ENST00000308162 CFL1 P23528 Cofilin-1 chr11 GO:0098590 Not Cancer Driver No 21 0.127 4 0 0.0 0
CHRM3_ENST00000615928 CHRM3 P20309 Muscarinic acetylcholine receptor M3 chr1 GO:0098590 Not Cancer Driver No 182 0.308 136 42 0.309 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 GO:0098590 Not Cancer Driver No 284 0.14 1017 160 0.157 3
CLCA2 CLCA2 Q9UQC9 Calcium-activated chloride channel regulator 2 chr1 GO:0098590 Not Cancer Driver No 131 0.139 222 35 0.158 0
CLDN3 CLDN3 O15551 Claudin-3 chr7 GO:0098590 Not Cancer Driver No 12 0.055 0 0 0.0 0
CLDN4 CLDN4 O14493 Claudin-4 chr7 GO:0098590 Not Cancer Driver No 40 0.191 0 0 0.0 0
CLDN5_ENST00000618236 CLDN5 O00501 Claudin-5 chr22 GO:0098590 Not Cancer Driver No 15 0.069 0 0 0.0 0
CLDN6 CLDN6 P56747 Claudin-6 chr16 GO:0098590 Not Cancer Driver No 52 0.236 0 0 0.0 0
CLDN8 CLDN8 P56748 Claudin-8 chr21 GO:0098590 Not Cancer Driver No 40 0.178 5 2 0.4 0
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 GO:0098590 Not Cancer Driver No 58 0.132 69 10 0.145 9
CLTA CLTA P09496 Clathrin light chain A chr9 GO:0098590 Not Cancer Driver No 20 0.081 192 12 0.062 0
CLTB CLTB P09497 Clathrin light chain B chr5 GO:0098590 Not Cancer Driver No 33 0.144 193 28 0.145 0
CNGA1_ENST00000420489 CNGA1 P29973 cGMP-gated cation channel alpha-1 chr4 GO:0098590 Not Cancer Driver No 136 0.198 185 37 0.2 1
CNTNAP1 CNTNAP1 P78357 Contactin-associated protein 1 chr17 GO:0098590 Not Cancer Driver No 173 0.125 141 15 0.106 6
CNTNAP2 CNTNAP2 Q9UHC6 Contactin-associated protein-like 2 chr7 GO:0098590 Census Yes 570 0.428 161 82 0.509 0
CRB2 CRB2 Q5IJ48 Protein crumbs homolog 2 chr9 GO:0098590 Not Cancer Driver No 155 0.121 72 0 0.0 5
CSPG4 CSPG4 Q6UVK1 Chondroitin sulfate proteoglycan 4 chr15 GO:0098590 Not Cancer Driver No 259 0.112 838 85 0.101 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0098590 Census, Compendium Yes 415 0.531 288 301 1.045 14
CUBN CUBN O60494 Cubilin chr10 GO:0098590 Not Cancer Driver No 709 0.196 272 54 0.199 2
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 GO:0098590 Not Cancer Driver No 51 0.14 98 19 0.194 0
CYBRD1 CYBRD1 Q53TN4 Plasma membrane ascorbate-dependent reductase CYBRD1 chr2 GO:0098590 Not Cancer Driver No 34 0.119 59 10 0.169 0
DAGLA DAGLA Q9Y4D2 Diacylglycerol lipase-alpha chr11 GO:0098590 Not Cancer Driver No 165 0.158 315 43 0.137 0
DCTN3 DCTN3 O75935 Dynactin subunit 3 chr9 GO:0098590 Not Cancer Driver No 18 0.097 3 0 0.0 0
DDN DDN O94850 Dendrin chr12 GO:0098590 Not Cancer Driver No 71 0.1 684 67 0.098 0
DHRS3 DHRS3 O75911 Short-chain dehydrogenase/reductase 3 chr1 GO:0098590 Not Cancer Driver No 33 0.109 0 0 0.0 0
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:0098590 Not Cancer Driver No 331 0.217 922 237 0.257 0
DMD DMD P11532 Dystrophin chrX GO:0098590 Not Cancer Driver No 895 0.243 1399 329 0.235 14
DNM1 DNM1 Q05193 Dynamin-1 chr9 GO:0098590 Not Cancer Driver No 98 0.113 280 23 0.082 4
DNM3_ENST00000355305 DNM3 Q9UQ16 Dynamin-3 chr1 GO:0098590 Not Cancer Driver No 166 0.191 257 45 0.175 0
DOCK8 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 GO:0098590 Not Cancer Driver No 321 0.153 312 60 0.192 1
DPEP1 DPEP1 P16444 Dipeptidase 1 chr16 GO:0098590 Not Cancer Driver No 54 0.131 41 6 0.146 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0098590 Not Cancer Driver No 151 0.197 8 1 0.125 0
DRD5 DRD5 P21918 D(1B) dopamine receptor chr4 GO:0098590 Not Cancer Driver No 172 0.361 29 18 0.621 0
DTNB DTNB O60941 Dystrobrevin beta chr2 GO:0098590 Not Cancer Driver No 75 0.12 337 42 0.125 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0098590 Not Cancer Driver No 104 0.114 284 33 0.116 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0098590 Not Cancer Driver No 34 0.149 25 6 0.24 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0098590 Census, Compendium Yes 444 0.367 223 35 0.157 1
EHD1_ENST00000359393 EHD1 Q9H4M9 EH domain-containing protein 1 chr11 GO:0098590 Not Cancer Driver No 72 0.135 90 12 0.133 0
EHD2 EHD2 Q9NZN4 EH domain-containing protein 2 chr19 GO:0098590 Compendium Yes 85 0.157 125 12 0.096 0
EHD3 EHD3 Q9NZN3 EH domain-containing protein 3 chr2 GO:0098590 Not Cancer Driver No 104 0.194 77 18 0.234 0
EMP2_ENST00000536829 EMP2 P54851 Epithelial membrane protein 2 chr16 GO:0098590 Not Cancer Driver No 24 0.144 0 0 0.0 2
EPB41L3 EPB41L3 Q9Y2J2 Band 4.1-like protein 3 chr18 GO:0098590 Not Cancer Driver No 298 0.274 695 207 0.298 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0098590 Compendium Yes 171 0.175 187 39 0.209 3
EPPK1 EPPK1 P58107 Epiplakin chr8 GO:0098590 Not Cancer Driver No 417 0.082 1336 67 0.05 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0098590 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0098590 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0098590 Census, Compendium Yes 428 0.327 323 116 0.359 2
ERBIN_ENST00000284037 ERBIN Q96RT1 Erbin chr5 GO:0098590 Not Cancer Driver No 167 0.118 967 118 0.122 0
EZR EZR P15311 Ezrin chr6 GO:0098590 Census Yes 66 0.113 295 35 0.119 0
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0098590 Not Cancer Driver No 73 0.172 19 2 0.105 0
FAP FAP Q12884 Prolyl endopeptidase FAP chr2 GO:0098590 Not Cancer Driver No 158 0.208 6 2 0.333 0
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 GO:0098590 Not Cancer Driver No 65 0.231 94 18 0.191 1
FCHO2 FCHO2 Q0JRZ9 F-BAR domain only protein 2 chr5 GO:0098590 Not Cancer Driver No 79 0.098 373 45 0.121 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0098590 Not Cancer Driver No 71 0.104 101 10 0.099 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0098590 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 GO:0098590 Not Cancer Driver No 56 0.131 20 3 0.15 0
FOLR1_ENST00000393681 FOLR1 P15328 Folate receptor alpha chr11 GO:0098590 Not Cancer Driver No 41 0.16 13 3 0.231 0
FSD1 FSD1 Q9BTV5 Fibronectin type III and SPRY domain-containing protein 1 chr19 GO:0098590 Not Cancer Driver No 66 0.133 90 17 0.189 0
FXYD1_ENST00000455515 FXYD1 O00168 Phospholemman chr19 GO:0098590 Not Cancer Driver No 10 0.109 22 4 0.182 0
FZD6 FZD6 O60353 Frizzled-6 chr8 GO:0098590 Not Cancer Driver No 95 0.135 172 15 0.087 1
FZD9 FZD9 O00144 Frizzled-9 chr7 GO:0098590 Not Cancer Driver No 55 0.093 61 0 0.0 0
GABBR1 GABBR1 Q9UBS5 Gamma-aminobutyric acid type B receptor subunit 1 chr6 GO:0098590 Not Cancer Driver No 150 0.156 142 17 0.12 0
GABRA1_ENST00000638112 GABRA1 P14867 Gamma-aminobutyric acid receptor subunit alpha-1 chr5 GO:0098590 Not Cancer Driver No 175 0.384 58 31 0.534 6
GABRA2_ENST00000356504 GABRA2 P47869 Gamma-aminobutyric acid receptor subunit alpha-2 chr4 GO:0098590 Not Cancer Driver No 194 0.43 26 13 0.5 5
GABRA3_ENST00000535043 GABRA3 P34903 Gamma-aminobutyric acid receptor subunit alpha-3 chrX GO:0098590 Not Cancer Driver No 136 0.276 47 10 0.213 0
GABRA4 GABRA4 P48169 Gamma-aminobutyric acid receptor subunit alpha-4 chr4 GO:0098590 Not Cancer Driver No 191 0.345 179 82 0.458 0
GABRA5_ENST00000355395 GABRA5 P31644 Gamma-aminobutyric acid receptor subunit alpha-5 chr15 GO:0098590 Not Cancer Driver No 146 0.316 55 14 0.255 3
GABRA6 GABRA6 Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 chr5 GO:0098590 Not Cancer Driver No 186 0.411 7 2 0.286 0
GABRE GABRE P78334 Gamma-aminobutyric acid receptor subunit epsilon chrX GO:0098590 Not Cancer Driver No 133 0.263 73 19 0.26 0
GABRG1 GABRG1 Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 chr4 GO:0098590 Not Cancer Driver No 216 0.465 7 3 0.429 0
GABRG2_ENST00000639213 GABRG2 P18507 Gamma-aminobutyric acid receptor subunit gamma-2 chr5 GO:0098590 Not Cancer Driver No 188 0.403 19 13 0.684 11
GABRG3 GABRG3 Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 chr15 GO:0098590 Not Cancer Driver No 137 0.293 12 5 0.417 0
GAP43_ENST00000305124 GAP43 P17677 Neuromodulin chr3 GO:0098590 Not Cancer Driver No 79 0.332 238 79 0.332 0
GASK1A GASK1A Q9UFP1 Golgi-associated kinase 1A chr3 GO:0098590 Not Cancer Driver No 25 0.043 235 10 0.043 0
GNA12 GNA12 Q03113 Guanine nucleotide-binding protein subunit alpha-12 chr7 GO:0098590 Not Cancer Driver No 41 0.108 20 0 0.0 0
GNA13 GNA13 Q14344 Guanine nucleotide-binding protein subunit alpha-13 chr17 GO:0098590 Compendium Yes 52 0.138 32 4 0.125 0
GNAT1 GNAT1 P11488 Guanine nucleotide-binding protein G(t) subunit alpha-1 chr3 GO:0098590 Not Cancer Driver No 43 0.123 39 6 0.154 3
GNAT2 GNAT2 P19087 Guanine nucleotide-binding protein G(t) subunit alpha-2 chr1 GO:0098590 Not Cancer Driver No 38 0.107 44 7 0.159 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0098590 Not Cancer Driver No 65 0.173 13 5 0.385 0
GRIA1_ENST00000285900 GRIA1 P42261 Glutamate receptor 1 chr5 GO:0098590 Not Cancer Driver No 303 0.334 104 45 0.433 0
GUCY2D GUCY2D Q02846 Retinal guanylyl cyclase 1 chr17 GO:0098590 Not Cancer Driver No 138 0.125 205 34 0.166 32
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0098590 Not Cancer Driver No 112 0.213 124 25 0.202 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0098590 Not Cancer Driver No 178 0.147 409 59 0.144 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0098590 Not Cancer Driver No 94 0.278 85 22 0.259 0
HMCN1 HMCN1 Q96RW7 Hemicentin-1 chr1 GO:0098590 Not Cancer Driver No 1020 0.181 943 167 0.177 1
HMCN2 HMCN2 Q8NDA2 Hemicentin-2 chr9 GO:0098590 Not Cancer Driver No 44 0.009 1681 15 0.009 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0098590 Not Cancer Driver No 46 0.16 81 13 0.16 0
HPCA HPCA P84074 Neuron-specific calcium-binding protein hippocalcin chr1 GO:0098590 Not Cancer Driver No 24 0.124 42 4 0.095 3
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0098590 Census, Compendium Yes 100 0.138 254 43 0.169 0
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0098590 Not Cancer Driver No 105 0.223 44 8 0.182 0
HTR3A_ENST00000504030 HTR3A P46098 5-hydroxytryptamine receptor 3A chr11 GO:0098590 Not Cancer Driver No 127 0.266 45 13 0.289 0
ICAM2_ENST00000579687 ICAM2 P13598 Intercellular adhesion molecule 2 chr17 GO:0098590 Not Cancer Driver No 39 0.142 19 1 0.053 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0098590 Not Cancer Driver No 183 0.134 265 37 0.14 6
INSR INSR P06213 Insulin receptor chr19 GO:0098590 Not Cancer Driver No 190 0.137 280 57 0.204 64
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0098590 Not Cancer Driver No 161 0.13 1072 133 0.124 2
ITGA3 ITGA3 P26006 Integrin alpha-3 chr17 GO:0098590 Not Cancer Driver No 106 0.101 129 18 0.14 3
ITGA8 ITGA8 P53708 Integrin alpha-8 chr10 GO:0098590 Not Cancer Driver No 292 0.275 114 26 0.228 1
ITGA9 ITGA9 Q13797 Integrin alpha-9 chr3 GO:0098590 Not Cancer Driver No 137 0.132 70 14 0.2 0
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0098590 Census Yes 153 0.146 92 9 0.098 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0098590 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0098590 Not Cancer Driver No 124 0.157 66 5 0.076 30
ITGB4 ITGB4 P16144 Integrin beta-4 chr17 GO:0098590 Not Cancer Driver No 248 0.136 753 86 0.114 14
ITLN1 ITLN1 Q8WWA0 Intelectin-1 chr1 GO:0098590 Not Cancer Driver No 72 0.23 13 4 0.308 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0098590 Census, Compendium Yes 136 0.12 59 5 0.085 5
JUP JUP P14923 Junction plakoglobin chr17 GO:0098590 Not Cancer Driver No 112 0.15 241 37 0.154 0
KATNBL1 KATNBL1 Q9H079 KATNB1-like protein 1 chr15 GO:0098590 Not Cancer Driver No 36 0.118 125 21 0.168 0
KCNA2_ENST00000638616 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 GO:0098590 Not Cancer Driver No 96 0.192 82 16 0.195 5
KCNA5 KCNA5 P22460 Potassium voltage-gated channel subfamily A member 5 chr12 GO:0098590 Not Cancer Driver No 213 0.347 218 53 0.243 0
KCNB1_ENST00000635465 KCNB1 Q14721 Potassium voltage-gated channel subfamily B member 1 chr20 GO:0098590 Not Cancer Driver No 192 0.224 417 100 0.24 6
KCNC1_ENST00000379472 KCNC1 P48547 Potassium voltage-gated channel subfamily C member 1 chr11 GO:0098590 Not Cancer Driver No 91 0.178 110 18 0.164 1
KCNC2 KCNC2 Q96PR1 Potassium voltage-gated channel subfamily C member 2 chr12 GO:0098590 Not Cancer Driver No 161 0.252 255 63 0.247 0
KCNC3 KCNC3 Q14003 Potassium voltage-gated channel subfamily C member 3 chr19 GO:0098590 Not Cancer Driver No 76 0.1 405 29 0.072 4
KCNC4 KCNC4 Q03721 Potassium voltage-gated channel subfamily C member 4 chr1 GO:0098590 Not Cancer Driver No 105 0.165 244 38 0.156 0
KCNK1 KCNK1 O00180 Potassium channel subfamily K member 1 chr1 GO:0098590 Not Cancer Driver No 65 0.193 21 4 0.19 0
KCNMA1 KCNMA1 Q12791 Calcium-activated potassium channel subunit alpha-1 chr10 GO:0098590 Not Cancer Driver No 222 0.18 225 39 0.173 5
KCNQ4_ENST00000347132 KCNQ4 P56696 Potassium voltage-gated channel subfamily KQT member 4 chr1 GO:0098590 Not Cancer Driver No 83 0.119 267 31 0.116 7
KIF17 KIF17 Q9P2E2 Kinesin-like protein KIF17 chr1 GO:0098590 Not Cancer Driver No 191 0.186 600 113 0.188 0
KIF18A KIF18A Q8NI77 Kinesin-like protein KIF18A chr11 GO:0098590 Not Cancer Driver No 114 0.127 405 60 0.148 0
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 GO:0098590 Not Cancer Driver No 79 0.089 340 40 0.118 1
KIFAP3 KIFAP3 Q92845 Kinesin-associated protein 3 chr1 GO:0098590 Not Cancer Driver No 116 0.146 71 10 0.141 0
KLHDC8B KLHDC8B Q8IXV7 Kelch domain-containing protein 8B chr3 GO:0098590 Not Cancer Driver No 37 0.105 16 0 0.0 0
KRT19 KRT19 P08727 Keratin, type I cytoskeletal 19 chr17 GO:0098590 Not Cancer Driver No 57 0.142 165 19 0.115 0
LAMP5 LAMP5 Q9UJQ1 Lysosome-associated membrane glycoprotein 5 chr20 GO:0098590 Not Cancer Driver No 86 0.307 40 20 0.5 0
LDLRAP1 LDLRAP1 Q5SW96 Low density lipoprotein receptor adapter protein 1 chr1 GO:0098590 Not Cancer Driver No 36 0.117 119 17 0.143 1
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 GO:0098590 Not Cancer Driver No 88 0.116 687 81 0.118 0
LIPE LIPE Q05469 Hormone-sensitive lipase chr19 GO:0098590 Not Cancer Driver No 123 0.114 496 65 0.131 0
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0098590 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRP6 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0098590 Not Cancer Driver No 206 0.128 255 30 0.118 5
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0098590 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0098590 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAL MAL P21145 Myelin and lymphocyte protein chr2 GO:0098590 Not Cancer Driver No 21 0.137 0 0 0.0 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0098590 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0098590 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0098590 Not Cancer Driver No 128 0.169 750 126 0.168 18
MASTL MASTL Q96GX5 Serine/threonine-protein kinase greatwall chr10 GO:0098590 Not Cancer Driver No 90 0.102 389 44 0.113 0
MEN1 MEN1 O00255 Menin chr11 GO:0098590 Census, Compendium Yes 73 0.119 228 15 0.066 90
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0098590 Census, Compendium Yes 226 0.163 62 15 0.242 19
MFSD10 MFSD10 Q14728 Major facilitator superfamily domain-containing protein 10 chr4 GO:0098590 Not Cancer Driver No 49 0.108 18 1 0.056 0
MLC1 MLC1 Q15049 Membrane protein MLC1 chr22 GO:0098590 Not Cancer Driver No 53 0.141 35 7 0.2 15
MPDZ MPDZ O75970 Multiple PDZ domain protein chr9 GO:0098590 Not Cancer Driver No 287 0.139 858 122 0.142 0
MPP2_ENST00000461854 MPP2 Q14168 MAGUK p55 subfamily member 2 chr17 GO:0098590 Not Cancer Driver No 109 0.189 112 18 0.161 0
MSN MSN P26038 Moesin chrX GO:0098590 Census, Compendium Yes 108 0.187 286 56 0.196 1
MST1R MST1R Q04912 Macrophage-stimulating protein receptor chr3 GO:0098590 Not Cancer Driver No 178 0.127 182 27 0.148 1
MTCL1_ENST00000306329 MTCL1 Q9Y4B5 Microtubule cross-linking factor 1 chr18 GO:0098590 Not Cancer Driver No 267 0.14 1681 232 0.138 0
MTTP_ENST00000265517 MTTP P55157 Microsomal triglyceride transfer protein large subunit chr4 GO:0098590 Not Cancer Driver No 165 0.185 47 11 0.234 8
MUC20 MUC20 Q8N307 Mucin-20 chr3 GO:0098590 Not Cancer Driver No 107 0.151 680 100 0.147 0
MYH10_ENST00000269243 MYH10 P35580 Myosin-10 chr17 GO:0098590 Not Cancer Driver No 258 0.131 1134 136 0.12 0
MYH9 MYH9 P35579 Myosin-9 chr22 GO:0098590 Census, Compendium Yes 310 0.158 1120 160 0.143 17
MYLK MYLK Q15746 Myosin light chain kinase, smooth muscle chr3 GO:0098590 Not Cancer Driver No 343 0.179 957 184 0.192 3
MYO10 MYO10 Q9HD67 Unconventional myosin-X chr5 GO:0098590 Not Cancer Driver No 296 0.144 418 59 0.141 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 GO:0098590 Not Cancer Driver No 110 0.103 66 11 0.167 0
MYO1D MYO1D O94832 Unconventional myosin-Id chr17 GO:0098590 Not Cancer Driver No 126 0.125 61 6 0.098 0
MYOF MYOF Q9NZM1 Myoferlin chr10 GO:0098590 Not Cancer Driver No 269 0.131 401 55 0.137 0
NAPEPLD NAPEPLD Q6IQ20 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D chr7 GO:0098590 Not Cancer Driver No 55 0.14 76 7 0.092 0
NCKAP1_ENST00000361354 NCKAP1 Q9Y2A7 Nck-associated protein 1 chr2 GO:0098590 Not Cancer Driver No 129 0.114 44 3 0.068 0
NDE1_ENST00000396354 NDE1 Q9NXR1 Nuclear distribution protein nudE homolog 1 chr16 GO:0098590 Not Cancer Driver No 45 0.134 316 42 0.133 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0098590 Not Cancer Driver No 150 0.114 711 79 0.111 0
NF2 NF2 P35240 Merlin chr22 GO:0098590 Census, Compendium Yes 69 0.116 252 26 0.103 16
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 GO:0098590 Not Cancer Driver No 94 0.186 255 53 0.208 1
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0098590 Not Cancer Driver No 168 0.14 347 38 0.11 0
OCLN OCLN Q16625 Occludin chr5 GO:0098590 Not Cancer Driver No 54 0.103 244 21 0.086 1
OPN4_ENST00000241891 OPN4 Q9UHM6 Melanopsin chr10 GO:0098590 Not Cancer Driver No 84 0.176 88 9 0.102 0
OPRD1 OPRD1 P41143 Delta-type opioid receptor chr1 GO:0098590 Not Cancer Driver No 91 0.245 30 3 0.1 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0098590 Not Cancer Driver No 107 0.268 58 27 0.466 0
OR2A4 OR2A4 O95047 Olfactory receptor 2A4 chr6 GO:0098590 Not Cancer Driver No 44 0.142 0 0 0.0 0
OSCP1 OSCP1 Q8WVF1 Protein OSCP1 chr1 GO:0098590 Not Cancer Driver No 54 0.139 130 22 0.169 0
OTOF OTOF Q9HC10 Otoferlin chr2 GO:0098590 Not Cancer Driver No 380 0.19 591 124 0.21 14
PACSIN2_ENST00000402229 PACSIN2 Q9UNF0 Protein kinase C and casein kinase substrate in neurons protein 2 chr22 GO:0098590 Not Cancer Driver No 51 0.105 301 27 0.09 0
PALM PALM O75781 Paralemmin-1 chr19 GO:0098590 Not Cancer Driver No 50 0.129 381 50 0.131 0
PDE6A PDE6A P16499 Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chr5 GO:0098590 Not Cancer Driver No 139 0.162 91 12 0.132 5
PDE6B PDE6B P35913 Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta chr4 GO:0098590 Not Cancer Driver No 144 0.169 44 9 0.205 13
PDE6G PDE6G P18545 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma chr17 GO:0098590 Not Cancer Driver No 15 0.172 58 11 0.19 0
PDE6H PDE6H Q13956 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma chr12 GO:0098590 Not Cancer Driver No 15 0.181 59 14 0.237 0
PDPN_ENST00000621990 PDPN Q86YL7 Podoplanin chr1 GO:0098590 Not Cancer Driver No 37 0.228 96 24 0.25 0
PDXP PDXP Q96GD0 Chronophin chr22 GO:0098590 Not Cancer Driver No 14 0.047 38 4 0.105 0
PDZK1_ENST00000344770 PDZK1 Q5T2W1 Na(+)/H(+) exchange regulatory cofactor NHE-RF3 chr1 GO:0098590 Not Cancer Driver No 39 0.075 248 14 0.056 0
PEX19 PEX19 P40855 Peroxisomal biogenesis factor 19 chr1 GO:0098590 Not Cancer Driver No 41 0.137 266 38 0.143 0
PHLPP2 PHLPP2 Q6ZVD8 PH domain leucine-rich repeat-containing protein phosphatase 2 chr16 GO:0098590 Not Cancer Driver No 157 0.119 309 37 0.12 0
PIEZO1 PIEZO1 Q92508 Piezo-type mechanosensitive ion channel component 1 chr16 GO:0098590 Not Cancer Driver No 122 0.048 471 26 0.055 12
PITPNM1_ENST00000534749 PITPNM1 O00562 Membrane-associated phosphatidylinositol transfer protein 1 chr11 GO:0098590 Not Cancer Driver No 157 0.126 477 69 0.145 0
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0098590 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 GO:0098590 Not Cancer Driver No 120 0.127 459 54 0.118 0
PKN2 PKN2 Q16513 Serine/threonine-protein kinase N2 chr1 GO:0098590 Not Cancer Driver No 123 0.125 415 48 0.116 0
PLB1 PLB1 Q6P1J6 Phospholipase B1, membrane-associated chr2 GO:0098590 Not Cancer Driver No 223 0.153 399 57 0.143 0
PLCD3 PLCD3 Q8N3E9 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 chr17 GO:0098590 Not Cancer Driver No 61 0.077 229 22 0.096 0
PLEK2 PLEK2 Q9NYT0 Pleckstrin-2 chr14 GO:0098590 Not Cancer Driver No 41 0.116 25 5 0.2 0
PLEKHG6_ENST00000011684 PLEKHG6 Q3KR16 Pleckstrin homology domain-containing family G member 6 chr12 GO:0098590 Not Cancer Driver No 103 0.13 471 65 0.138 0
PLEKHO1 PLEKHO1 Q53GL0 Pleckstrin homology domain-containing family O member 1 chr1 GO:0098590 Not Cancer Driver No 55 0.134 341 46 0.135 0
PLK4 PLK4 O00444 Serine/threonine-protein kinase PLK4 chr4 GO:0098590 Not Cancer Driver No 102 0.105 451 45 0.1 0
PLPP1_ENST00000307259 PLPP1 O14494 Phospholipid phosphatase 1 chr5 GO:0098590 Not Cancer Driver No 28 0.099 27 1 0.037 0
PLPP2_ENST00000434325 PLPP2 O43688 Phospholipid phosphatase 2 chr19 GO:0098590 Not Cancer Driver No 47 0.163 0 0 0.0 0
PLVAP PLVAP Q9BX97 Plasmalemma vesicle-associated protein chr19 GO:0098590 Not Cancer Driver No 96 0.217 174 39 0.224 1
PLXND1 PLXND1 Q9Y4D7 Plexin-D1 chr3 GO:0098590 Not Cancer Driver No 246 0.128 321 35 0.109 0
PODXL PODXL O00592 Podocalyxin chr7 GO:0098590 Not Cancer Driver No 69 0.124 432 56 0.13 0
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 GO:0098590 Not Cancer Driver No 26 0.08 23 4 0.174 0
PRCD_ENST00000592014 PRCD Q00LT1 Photoreceptor disk component PRCD chr17 GO:0098590 Not Cancer Driver No 3 0.056 35 2 0.057 2
PROM1 PROM1 O43490 Prominin-1 chr4 GO:0098590 Not Cancer Driver No 94 0.109 76 9 0.118 3
PROM2_ENST00000403131 PROM2 Q8N271 Prominin-2 chr2 GO:0098590 Not Cancer Driver No 111 0.133 34 4 0.118 0
PSD PSD A5PKW4 PH and SEC7 domain-containing protein 1 chr10 GO:0098590 Not Cancer Driver No 173 0.169 714 130 0.182 0
PSD2 PSD2 Q9BQI7 PH and SEC7 domain-containing protein 2 chr5 GO:0098590 Not Cancer Driver No 155 0.201 398 87 0.219 0
PSD4 PSD4 Q8NDX1 PH and SEC7 domain-containing protein 4 chr2 GO:0098590 Not Cancer Driver No 157 0.149 739 103 0.139 0
PSTPIP1 PSTPIP1 O43586 Proline-serine-threonine phosphatase-interacting protein 1 chr15 GO:0098590 Not Cancer Driver No 46 0.111 225 26 0.116 3
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0098590 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTGIS PTGIS Q16647 Prostacyclin synthase chr20 GO:0098590 Not Cancer Driver No 102 0.204 18 3 0.167 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0098590 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTPRH PTPRH Q9HD43 Receptor-type tyrosine-protein phosphatase H chr19 GO:0098590 Not Cancer Driver No 228 0.204 474 74 0.156 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 GO:0098590 Not Cancer Driver No 31 0.144 43 4 0.093 0
RAB11FIP3 RAB11FIP3 O75154 Rab11 family-interacting protein 3 chr16 GO:0098590 Not Cancer Driver No 51 0.067 605 33 0.055 0
RAB11FIP4 RAB11FIP4 Q86YS3 Rab11 family-interacting protein 4 chr17 GO:0098590 Not Cancer Driver No 76 0.119 434 54 0.124 0
RAB21 RAB21 Q9UL25 Ras-related protein Rab-21 chr12 GO:0098590 Not Cancer Driver No 23 0.102 59 4 0.068 0
RAB25 RAB25 P57735 Ras-related protein Rab-25 chr1 GO:0098590 Not Cancer Driver No 26 0.122 32 5 0.156 0
RACGAP1_ENST00000454520 RACGAP1 Q9H0H5 Rac GTPase-activating protein 1 chr12 GO:0098590 Not Cancer Driver No 74 0.117 255 27 0.106 0
RALA RALA P11233 Ras-related protein Ral-A chr7 GO:0098590 Not Cancer Driver No 34 0.165 34 3 0.088 5
RANGRF RANGRF Q9HD47 Ran guanine nucleotide release factor chr17 GO:0098590 Not Cancer Driver No 10 0.054 42 5 0.119 0
RDH12_ENST00000267502 RDH12 Q96NR8 Retinol dehydrogenase 12 chr14 GO:0098590 Not Cancer Driver No 41 0.13 0 0 0.0 10
RDX_ENST00000343115 RDX P35241 Radixin chr11 GO:0098590 Not Cancer Driver No 71 0.122 297 37 0.125 1
RHO RHO P08100 Rhodopsin chr3 GO:0098590 Not Cancer Driver No 68 0.195 18 3 0.167 69
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0098590 Census, Compendium Yes 99 0.513 46 13 0.283 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 GO:0098590 Not Cancer Driver No 52 0.265 19 2 0.105 0
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 GO:0098590 Not Cancer Driver No 30 0.155 53 7 0.132 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0098590 Not Cancer Driver No 131 0.123 421 76 0.181 0
ROBO2_ENST00000461745 ROBO2 Q9HCK4 Roundabout homolog 2 chr3 GO:0098590 Census Yes 407 0.295 874 259 0.296 2
ROM1 ROM1 Q03395 Rod outer segment membrane protein 1 chr11 GO:0098590 Not Cancer Driver No 41 0.117 26 4 0.154 0
RP2 RP2 O75695 Protein XRP2 chrX GO:0098590 Not Cancer Driver No 45 0.129 28 6 0.214 10
S100P S100P P25815 Protein S100-P chr4 GO:0098590 Not Cancer Driver No 7 0.074 3 1 0.333 0
SCARB1_ENST00000415380 SCARB1 Q8WTV0 Scavenger receptor class B member 1 chr12 GO:0098590 Not Cancer Driver No 53 0.096 6 1 0.167 0
SCIMP SCIMP Q6UWF3 SLP adapter and CSK-interacting membrane protein chr17 GO:0098590 Not Cancer Driver No 10 0.069 73 9 0.123 0
SCN5A_ENST00000333535 SCN5A Q14524 Sodium channel protein type 5 subunit alpha chr3 GO:0098590 Not Cancer Driver No 491 0.244 550 144 0.262 190
SELE SELE P16581 E-selectin chr1 GO:0098590 Not Cancer Driver No 137 0.225 12 0 0.0 0
SEPT12 SEPTIN12 Q8IYM1 Septin-12 chr16 GO:0098590 Not Cancer Driver No 69 0.193 62 8 0.129 2
SEPT2_ENST00000360051 SEPTIN2 Q15019 Septin-2 chr2 GO:0098590 Not Cancer Driver No 49 0.136 101 11 0.109 0
SEPT6 SEPTIN6 Q14141 Septin-6 chrX GO:0098590 Not Cancer Driver No 69 0.159 161 25 0.155 0
SEPT7_ENST00000350320 SEPTIN7 Q16181 Septin-7 chr7 GO:0098590 Not Cancer Driver No 49 0.112 200 21 0.105 0
SGCE_ENST00000265735 SGCE O43556 Epsilon-sarcoglycan chr7 GO:0098590 Not Cancer Driver No 69 0.158 111 13 0.117 13
SHANK2_ENST00000601538 SHANK2 Q9UPX8 SH3 and multiple ankyrin repeat domains protein 2 chr11 GO:0098590 Not Cancer Driver No 303 0.164 1379 262 0.19 0
SHISA6_ENST00000409168 SHISA6 Q6ZSJ9 Protein shisa-6 chr17 GO:0098590 Not Cancer Driver No 29 0.058 330 22 0.067 0
SHISA7 SHISA7 A6NL88 Protein shisa-7 chr19 GO:0098590 Not Cancer Driver No 13 0.024 429 12 0.028 0
SHISA9 SHISA9 B4DS77 Protein shisa-9 chr16 GO:0098590 Not Cancer Driver No 28 0.066 285 23 0.081 0
SHROOM4 SHROOM4 Q9ULL8 Protein Shroom4 chrX GO:0098590 Not Cancer Driver No 242 0.162 1027 167 0.163 1
SLC11A2_ENST00000262051 SLC11A2 P49281 Natural resistance-associated macrophage protein 2 chr12 GO:0098590 Not Cancer Driver No 60 0.106 38 5 0.132 3
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 GO:0098590 Not Cancer Driver No 141 0.116 297 18 0.061 8
SLC12A5 SLC12A5 Q9H2X9 Solute carrier family 12 member 5 chr20 GO:0098590 Not Cancer Driver No 263 0.231 290 59 0.203 5
SLC16A1 SLC16A1 P53985 Monocarboxylate transporter 1 chr1 GO:0098590 Not Cancer Driver No 69 0.138 70 3 0.043 3
SLC17A3_ENST00000360657 SLC17A3 O00476 Sodium-dependent phosphate transport protein 4 chr6 GO:0098590 Not Cancer Driver No 97 0.231 26 6 0.231 0
SLC19A1 SLC19A1 P41440 Reduced folate transporter chr21 GO:0098590 Not Cancer Driver No 77 0.13 144 7 0.049 0
SLC1A2 SLC1A2 P43004 Excitatory amino acid transporter 2 chr11 GO:0098590 Not Cancer Driver No 77 0.134 81 7 0.086 3
SLC1A3 SLC1A3 P43003 Excitatory amino acid transporter 1 chr5 GO:0098590 Not Cancer Driver No 100 0.185 55 9 0.164 1
SLC1A5 SLC1A5 Q15758 Neutral amino acid transporter B(0) chr19 GO:0098590 Not Cancer Driver No 52 0.096 61 7 0.115 0
SLC22A12 SLC22A12 Q96S37 Solute carrier family 22 member 12 chr11 GO:0098590 Not Cancer Driver No 93 0.168 10 3 0.3 10
SLC22A5_ENST00000245407 SLC22A5 O76082 Solute carrier family 22 member 5 chr5 GO:0098590 Not Cancer Driver No 53 0.095 15 2 0.133 73
SLC22A6 SLC22A6 Q4U2R8 Solute carrier family 22 member 6 chr11 GO:0098590 Not Cancer Driver No 85 0.151 72 11 0.153 0
SLC23A1_ENST00000348729 SLC23A1 Q9UHI7 Solute carrier family 23 member 1 chr5 GO:0098590 Not Cancer Driver No 74 0.124 47 5 0.106 0
SLC26A2 SLC26A2 P50443 Sulfate transporter chr5 GO:0098590 Not Cancer Driver No 71 0.096 41 3 0.073 9
SLC26A3 SLC26A3 P40879 Chloride anion exchanger chr7 GO:0098590 Not Cancer Driver No 159 0.208 3 1 0.333 26
SLC26A4_ENST00000644269 SLC26A4 O43511 Pendrin chr7 GO:0098590 Not Cancer Driver No 129 0.165 10 0 0.0 73
SLC26A6 SLC26A6 Q9BXS9 Solute carrier family 26 member 6 chr3 GO:0098590 Not Cancer Driver No 68 0.09 87 13 0.149 0
SLC27A1 SLC27A1 Q6PCB7 Long-chain fatty acid transport protein 1 chr19 GO:0098590 Not Cancer Driver No 88 0.136 16 0 0.0 0
SLC27A4 SLC27A4 Q6P1M0 Long-chain fatty acid transport protein 4 chr9 GO:0098590 Not Cancer Driver No 83 0.129 27 3 0.111 5
SLC27A5 SLC27A5 Q9Y2P5 Bile acyl-CoA synthetase chr19 GO:0098590 Not Cancer Driver No 107 0.155 7 2 0.286 0
SLC28A1_ENST00000286749 SLC28A1 O00337 Sodium/nucleoside cotransporter 1 chr15 GO:0098590 Not Cancer Driver No 121 0.186 15 7 0.467 3
SLC28A2 SLC28A2 O43868 Sodium/nucleoside cotransporter 2 chr15 GO:0098590 Not Cancer Driver No 93 0.141 36 6 0.167 0
SLC28A3 SLC28A3 Q9HAS3 Solute carrier family 28 member 3 chr9 GO:0098590 Not Cancer Driver No 104 0.151 83 9 0.108 0
SLC2A1 SLC2A1 P11166 Solute carrier family 2, facilitated glucose transporter member 1 chr1 GO:0098590 Not Cancer Driver No 51 0.104 13 2 0.154 48
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0098590 Not Cancer Driver No 92 0.144 46 8 0.174 9
SLC34A2 SLC34A2 O95436 Sodium-dependent phosphate transport protein 2B chr4 GO:0098590 Census Yes 132 0.191 65 15 0.231 1
SLC34A3_ENST00000361134 SLC34A3 Q8N130 Sodium-dependent phosphate transport protein 2C chr9 GO:0098590 Not Cancer Driver No 56 0.093 63 9 0.143 6
SLC39A6_ENST00000590986 SLC39A6 Q13433 Zinc transporter ZIP6 chr18 GO:0098590 Not Cancer Driver No 86 0.114 360 37 0.103 0
SLC3A1 SLC3A1 Q07837 Neutral and basic amino acid transport protein rBAT chr2 GO:0098590 Not Cancer Driver No 103 0.15 90 20 0.222 49
SLC3A2_ENST00000377890 SLC3A2 P08195 4F2 cell-surface antigen heavy chain chr11 GO:0098590 Not Cancer Driver No 62 0.098 171 12 0.07 0
SLC46A1 SLC46A1 Q96NT5 Proton-coupled folate transporter chr17 GO:0098590 Not Cancer Driver No 37 0.081 31 0 0.0 13
SLC5A1 SLC5A1 P13866 Sodium/glucose cotransporter 1 chr22 GO:0098590 Not Cancer Driver No 104 0.157 47 2 0.043 22
SLC5A6 SLC5A6 Q9Y289 Sodium-dependent multivitamin transporter chr2 GO:0098590 Not Cancer Driver No 87 0.137 28 0 0.0 2
SLC6A18 SLC6A18 Q96N87 Inactive sodium-dependent neutral amino acid transporter B(0)AT3 chr5 GO:0098590 Not Cancer Driver No 122 0.194 37 5 0.135 0
SLC6A19 SLC6A19 Q695T7 Sodium-dependent neutral amino acid transporter B(0)AT1 chr5 GO:0098590 Not Cancer Driver No 130 0.205 1 0 0.0 14
SLC6A6_ENST00000622186 SLC6A6 P31641 Sodium- and chloride-dependent taurine transporter chr3 GO:0098590 Not Cancer Driver No 80 0.129 22 1 0.045 2
SLC6A9 SLC6A9 P48067 Sodium- and chloride-dependent glycine transporter 1 chr1 GO:0098590 Not Cancer Driver No 102 0.144 65 12 0.185 1
SLC7A1 SLC7A1 P30825 High affinity cationic amino acid transporter 1 chr13 GO:0098590 Not Cancer Driver No 89 0.141 17 3 0.176 0
SLC7A11 SLC7A11 Q9UPY5 Cystine/glutamate transporter chr4 GO:0098590 Not Cancer Driver No 70 0.14 15 2 0.133 0
SLC7A5 SLC7A5 Q01650 Large neutral amino acids transporter small subunit 1 chr16 GO:0098590 Not Cancer Driver No 62 0.122 35 1 0.029 0
SLC7A8 SLC7A8 Q9UHI5 Large neutral amino acids transporter small subunit 2 chr14 GO:0098590 Not Cancer Driver No 70 0.131 63 11 0.175 0
SLC7A9_ENST00000587772 SLC7A9 P82251 b(0,+)-type amino acid transporter 1 chr19 GO:0098590 Not Cancer Driver No 97 0.199 24 4 0.167 34
SLC9A3 SLC9A3 P48764 Sodium/hydrogen exchanger 3 chr5 GO:0098590 Not Cancer Driver No 105 0.126 225 30 0.133 3
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0098590 Not Cancer Driver No 19 0.053 318 16 0.05 4
SMO SMO Q99835 Smoothened homolog chr7 GO:0098590 Census, Compendium Yes 112 0.142 241 27 0.112 1
SMPD2 SMPD2 O60906 Sphingomyelin phosphodiesterase 2 chr6 GO:0098590 Not Cancer Driver No 45 0.106 48 5 0.104 0
SNAP29 SNAP29 O95721 Synaptosomal-associated protein 29 chr22 GO:0098590 Not Cancer Driver No 21 0.081 246 20 0.081 0
SPIRE1 SPIRE1 Q08AE8 Protein spire homolog 1 chr18 GO:0098590 Not Cancer Driver No 78 0.103 414 48 0.116 0
SPIRE2 SPIRE2 Q8WWL2 Protein spire homolog 2 chr16 GO:0098590 Not Cancer Driver No 79 0.111 344 43 0.125 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:0098590 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 GO:0098590 Not Cancer Driver No 311 0.132 869 123 0.142 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0098590 Census Yes 53 0.099 130 11 0.085 1
SSH1 SSH1 Q8WYL5 Protein phosphatase Slingshot homolog 1 chr12 GO:0098590 Not Cancer Driver No 129 0.123 658 85 0.129 0
STAMBP_ENST00000339566 STAMBP O95630 STAM-binding protein chr2 GO:0098590 Not Cancer Driver No 51 0.12 139 16 0.115 6
STX11 STX11 O75558 Syntaxin-11 chr6 GO:0098590 Not Cancer Driver No 71 0.247 48 7 0.146 0
STX19 STX19 Q8N4C7 Syntaxin-19 chr3 GO:0098590 Not Cancer Driver No 39 0.133 67 4 0.06 0
STX1A STX1A Q16623 Syntaxin-1A chr7 GO:0098590 Not Cancer Driver No 35 0.122 136 11 0.081 0
STX1B STX1B P61266 Syntaxin-1B chr16 GO:0098590 Not Cancer Driver No 38 0.132 155 20 0.129 2
STX2 STX2 P32856 Syntaxin-2 chr12 GO:0098590 Not Cancer Driver No 43 0.149 140 25 0.179 0
STX3 STX3 Q13277 Syntaxin-3 chr11 GO:0098590 Not Cancer Driver No 51 0.176 129 30 0.233 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0098590 Not Cancer Driver No 50 0.168 152 20 0.132 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0098590 Not Cancer Driver No 97 0.163 111 23 0.207 18
SVIL SVIL O95425 Supervillin chr10 GO:0098590 Not Cancer Driver No 308 0.139 1423 192 0.135 0
SYNE2_ENST00000344113 SYNE2 Q8WXH0 Nesprin-2 chr14 GO:0098590 Not Cancer Driver No 779 0.113 1888 220 0.117 1
SYT11 SYT11 Q9BT88 Synaptotagmin-11 chr1 GO:0098590 Not Cancer Driver No 64 0.148 105 23 0.219 0
SYTL1_ENST00000616558 SYTL1 Q8IYJ3 Synaptotagmin-like protein 1 chr1 GO:0098590 Not Cancer Driver No 64 0.114 328 41 0.125 0
TACR3 TACR3 P29371 Neuromedin-K receptor chr4 GO:0098590 Not Cancer Driver No 137 0.295 31 17 0.548 5
TACSTD2 TACSTD2 P09758 Tumor-associated calcium signal transducer 2 chr1 GO:0098590 Not Cancer Driver No 22 0.068 27 1 0.037 0
TBC1D10C TBC1D10C Q8IV04 Carabin chr11 GO:0098590 Not Cancer Driver No 58 0.13 192 32 0.167 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0098590 Not Cancer Driver No 219 0.195 126 22 0.175 10
TF TF P02787 Serotransferrin chr3 GO:0098590 Not Cancer Driver No 135 0.193 21 5 0.238 2
TFPI TFPI P10646 Tissue factor pathway inhibitor chr2 GO:0098590 Not Cancer Driver No 47 0.155 28 2 0.071 0
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0098590 Census, Compendium Yes 106 0.187 60 16 0.267 25
THBD THBD P07204 Thrombomodulin chr20 GO:0098590 Not Cancer Driver No 39 0.068 51 3 0.059 9
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0098590 Not Cancer Driver No 24 0.149 5 0 0.0 0
TMEM114 TMEM114 B3SHH9 Transmembrane protein 114 chr16 GO:0098590 Not Cancer Driver No 1 0.004 7 0 0.0 0
TRPC4_ENST00000379705 TRPC4 Q9UBN4 Short transient receptor potential channel 4 chr13 GO:0098590 Not Cancer Driver No 322 0.33 195 66 0.338 0
TRPM6 TRPM6 Q9BX84 Transient receptor potential cation channel subfamily M member 6 chr9 GO:0098590 Not Cancer Driver No 431 0.213 458 99 0.216 6
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0098590 Not Cancer Driver No 93 0.111 155 18 0.116 0
TTYH1_ENST00000376530 TTYH1 Q9H313 Protein tweety homolog 1 chr19 GO:0098590 Not Cancer Driver No 56 0.124 21 3 0.143 0
UNC5A UNC5A Q6ZN44 Netrin receptor UNC5A chr5 GO:0098590 Not Cancer Driver No 133 0.158 120 20 0.167 0
USH2A USH2A O75445 Usherin chr1 GO:0098590 Not Cancer Driver No 1503 0.289 773 235 0.304 70
UTRN UTRN P46939 Utrophin chr6 GO:0098590 Not Cancer Driver No 476 0.139 1283 183 0.143 0
VASP VASP P50552 Vasodilator-stimulated phosphoprotein chr19 GO:0098590 Not Cancer Driver No 39 0.103 335 34 0.101 0
VEZT VEZT Q9HBM0 Vezatin chr12 GO:0098590 Not Cancer Driver No 83 0.107 278 22 0.079 0
WDR73 WDR73 Q6P4I2 WD repeat-containing protein 73 chr15 GO:0098590 Not Cancer Driver No 29 0.077 86 7 0.081 0
WHRN WHRN Q9P202 Whirlin chr9 GO:0098590 Not Cancer Driver No 119 0.131 484 53 0.11 0
ZFYVE19 ZFYVE19 Q96K21 Abscission/NoCut checkpoint regulator chr15 GO:0098590 Not Cancer Driver No 41 0.087 361 28 0.078 0