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Total number of protein in "GO:0097708" GO term:  262

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0097708 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABCA12 ABCA12 Q86UK0 Glucosylceramide transporter ABCA12 chr2 GO:0097708 Not Cancer Driver No 511 0.197 136 23 0.169 14
ABCA13 ABCA13 Q86UQ4 ATP-binding cassette sub-family A member 13 chr7 GO:0097708 Not Cancer Driver No 930 0.184 162 14 0.086 0
ABCA3 ABCA3 Q99758 Phospholipid-transporting ATPase ABCA3 chr16 GO:0097708 Not Cancer Driver No 224 0.131 77 4 0.052 13
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 GO:0097708 Not Cancer Driver No 73 0.195 42 10 0.238 16
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0097708 Not Cancer Driver No 82 0.1 230 13 0.057 0
AKAP5_ENST00000320636 AKAP5 P24588 A-kinase anchor protein 5 chr14 GO:0097708 Not Cancer Driver No 37 0.087 405 34 0.084 0
ANKFY1_ENST00000341657 ANKFY1 Q9P2R3 Rabankyrin-5 chr17 GO:0097708 Not Cancer Driver No 109 0.093 185 29 0.157 0
ANXA11 ANXA11 P50995 Annexin A11 chr10 GO:0097708 Not Cancer Driver No 63 0.125 244 31 0.127 1
ANXA3 ANXA3 P12429 Annexin A3 chr4 GO:0097708 Not Cancer Driver No 53 0.164 22 4 0.182 0
AP2A1 AP2A1 O95782 AP-2 complex subunit alpha-1 chr19 GO:0097708 Not Cancer Driver No 95 0.097 188 12 0.064 0
AP2A2_ENST00000448903 AP2A2 O94973 AP-2 complex subunit alpha-2 chr11 GO:0097708 Not Cancer Driver No 100 0.106 145 12 0.083 0
AP2B1_ENST00000621914 AP2B1 P63010 AP-2 complex subunit beta chr17 GO:0097708 Not Cancer Driver No 85 0.091 95 12 0.126 0
AP2M1_ENST00000292807 AP2M1 Q96CW1 AP-2 complex subunit mu chr3 GO:0097708 Not Cancer Driver No 55 0.126 41 9 0.22 1
AP2S1_ENST00000263270 AP2S1 P53680 AP-2 complex subunit sigma chr19 GO:0097708 Not Cancer Driver No 4 0.028 0 0 0.0 3
AP3B2_ENST00000261722 AP3B2 Q13367 AP-3 complex subunit beta-2 chr15 GO:0097708 Not Cancer Driver No 145 0.134 381 51 0.134 0
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 GO:0097708 Not Cancer Driver No 138 0.12 404 59 0.146 0
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0097708 Not Cancer Driver No 67 0.094 292 31 0.106 1
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0097708 Not Cancer Driver No 70 0.105 149 14 0.094 0
ARC ARC Q7LC44 Activity-regulated cytoskeleton-associated protein chr8 GO:0097708 Not Cancer Driver No 64 0.162 194 29 0.149 0
ARHGAP1 ARHGAP1 Q07960 Rho GTPase-activating protein 1 chr11 GO:0097708 Not Cancer Driver No 39 0.089 90 8 0.089 0
ASTL ASTL Q6HA08 Astacin-like metalloendopeptidase chr2 GO:0097708 Not Cancer Driver No 101 0.234 179 44 0.246 0
ATG14 ATG14 Q6ZNE5 Beclin 1-associated autophagy-related key regulator chr14 GO:0097708 Not Cancer Driver No 48 0.098 209 24 0.115 0
ATP13A2 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:0097708 Not Cancer Driver No 152 0.129 121 10 0.083 9
AZIN2_ENST00000294517 AZIN2 Q96A70 Antizyme inhibitor 2 chr1 GO:0097708 Not Cancer Driver No 51 0.111 14 0 0.0 0
AZU1 AZU1 P20160 Azurocidin chr19 GO:0097708 Not Cancer Driver No 42 0.167 53 13 0.245 0
BACE1 BACE1 P56817 Beta-secretase 1 chr11 GO:0097708 Not Cancer Driver No 55 0.11 53 5 0.094 0
BAIAP3 BAIAP3 O94812 BAI1-associated protein 3 chr16 GO:0097708 Not Cancer Driver No 170 0.143 230 35 0.152 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0097708 Not Cancer Driver No 45 0.1 190 19 0.1 0
BST2 BST2 Q10589 Bone marrow stromal antigen 2 chr19 GO:0097708 Not Cancer Driver No 19 0.106 20 0 0.0 0
CALR CALR P27797 Calreticulin chr19 GO:0097708 Census Yes 45 0.108 245 31 0.127 0
CAMP CAMP P49913 Cathelicidin antimicrobial peptide chr3 GO:0097708 Not Cancer Driver No 25 0.147 48 4 0.083 0
CARMIL1 CARMIL1 Q5VZK9 F-actin-uncapping protein LRRC16A chr6 GO:0097708 Not Cancer Driver No 171 0.125 537 87 0.162 0
CARMIL2 CARMIL2 Q6F5E8 Capping protein, Arp2/3 and myosin-I linker protein 2 chr16 GO:0097708 Not Cancer Driver No 154 0.107 669 75 0.112 4
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0097708 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD63_ENST00000552692 CD63 P08962 CD63 antigen chr12 GO:0097708 Not Cancer Driver No 27 0.113 0 0 0.0 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0097708 Census Yes 31 0.105 185 20 0.108 0
CD79A CD79A P11912 B-cell antigen receptor complex-associated protein alpha chain chr19 GO:0097708 Census Yes 32 0.142 28 3 0.107 0
CDC42EP2 CDC42EP2 O14613 Cdc42 effector protein 2 chr11 GO:0097708 Not Cancer Driver No 19 0.09 162 17 0.105 0
CDC42EP4 CDC42EP4 Q9H3Q1 Cdc42 effector protein 4 chr17 GO:0097708 Not Cancer Driver No 47 0.132 352 47 0.134 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0097708 Not Cancer Driver No 39 0.204 23 2 0.087 1
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0097708 Not Cancer Driver No 207 0.152 105 10 0.095 0
CHGA CHGA P10645 Chromogranin-A chr14 GO:0097708 Not Cancer Driver No 46 0.101 421 44 0.105 0
CHMP1A CHMP1A Q9HD42 Charged multivesicular body protein 1a chr16 GO:0097708 Not Cancer Driver No 18 0.092 110 6 0.055 0
CHMP1B CHMP1B Q7LBR1 Charged multivesicular body protein 1b chr18 GO:0097708 Not Cancer Driver No 23 0.116 133 16 0.12 0
CHMP2A_ENST00000601220 CHMP2A O43633 Charged multivesicular body protein 2a chr19 GO:0097708 Not Cancer Driver No 29 0.131 161 22 0.137 0
CHMP2B CHMP2B Q9UQN3 Charged multivesicular body protein 2b chr3 GO:0097708 Not Cancer Driver No 28 0.131 183 25 0.137 4
CHMP3 CHMP3 Q9Y3E7 Charged multivesicular body protein 3 chr2 GO:0097708 Not Cancer Driver No 25 0.113 137 13 0.095 0
CHMP4A_ENST00000609024 CHMP4A Q9BY43 Charged multivesicular body protein 4a chr14 GO:0097708 Not Cancer Driver No 24 0.108 204 23 0.113 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 GO:0097708 Not Cancer Driver No 25 0.112 201 22 0.109 2
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 GO:0097708 Not Cancer Driver No 33 0.142 224 31 0.138 0
CHMP5 CHMP5 Q9NZZ3 Charged multivesicular body protein 5 chr9 GO:0097708 Not Cancer Driver No 24 0.11 195 18 0.092 0
CHMP6 CHMP6 Q96FZ7 Charged multivesicular body protein 6 chr17 GO:0097708 Not Cancer Driver No 26 0.129 88 16 0.182 0
CHMP7_ENST00000313219 CHMP7 Q8WUX9 Charged multivesicular body protein 7 chr8 GO:0097708 Not Cancer Driver No 50 0.11 140 15 0.107 0
CKAP4 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 GO:0097708 Not Cancer Driver No 73 0.121 409 55 0.134 0
CLCN3_ENST00000513761 CLCN3 P51790 H(+)/Cl(-) exchange transporter 3 chr4 GO:0097708 Not Cancer Driver No 105 0.128 88 7 0.08 0
CLIP1 CLIP1 P30622 CAP-Gly domain-containing linker protein 1 chr12 GO:0097708 Census, Compendium Yes 184 0.128 1194 136 0.114 0
CLSTN1 CLSTN1 O94985 Calsyntenin-1 chr1 GO:0097708 Not Cancer Driver No 110 0.112 271 22 0.081 0
CLTA CLTA P09496 Clathrin light chain A chr9 GO:0097708 Not Cancer Driver No 20 0.081 192 12 0.062 0
CLTB CLTB P09497 Clathrin light chain B chr5 GO:0097708 Not Cancer Driver No 33 0.144 193 28 0.145 0
CLTCL1 CLTCL1 P53675 Clathrin heavy chain 2 chr22 GO:0097708 Census, Compendium Yes 210 0.128 10 1 0.1 0
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 GO:0097708 Census, Compendium Yes 190 0.113 71 6 0.085 1
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0097708 Not Cancer Driver No 69 0.154 156 27 0.173 0
CORO1A CORO1A P31146 Coronin-1A chr16 GO:0097708 Not Cancer Driver No 51 0.111 126 15 0.119 1
CPNE6_ENST00000397016 CPNE6 O95741 Copine-6 chr14 GO:0097708 Not Cancer Driver No 85 0.153 111 22 0.198 0
CRACR2A CRACR2A Q9BSW2 EF-hand calcium-binding domain-containing protein 4B chr12 GO:0097708 Not Cancer Driver No 88 0.12 436 60 0.138 0
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0097708 Not Cancer Driver No 61 0.189 0 0 0.0 0
CST7 CST7 O76096 Cystatin-F chr20 GO:0097708 Not Cancer Driver No 12 0.083 15 2 0.133 0
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 GO:0097708 Not Cancer Driver No 37 0.166 3 0 0.0 1
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0097708 Not Cancer Driver No 45 0.134 4 0 0.0 0
CTSL CTSL P07711 Procathepsin L chr9 GO:0097708 Not Cancer Driver No 47 0.141 34 4 0.118 0
CTSS CTSS P25774 Cathepsin S chr1 GO:0097708 Not Cancer Driver No 54 0.163 0 0 0.0 0
DEFA4 DEFA4 P12838 Defensin alpha 4 chr8 GO:0097708 Not Cancer Driver No 35 0.361 17 5 0.294 0
DENND4C_ENST00000602925 DENND4C Q5VZ89 DENN domain-containing protein 4C chr9 GO:0097708 Not Cancer Driver No 190 0.1 710 69 0.097 0
DMXL2_ENST00000251076 DMXL2 Q8TDJ6 DmX-like protein 2 chr15 GO:0097708 Not Cancer Driver No 428 0.141 738 102 0.138 2
DNASE1_ENST00000246949 DNASE1 P24855 Deoxyribonuclease-1 chr16 GO:0097708 Not Cancer Driver No 24 0.085 0 0 0.0 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:0097708 Not Cancer Driver No 67 0.091 212 23 0.108 7
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0097708 Census Yes 138 0.159 270 43 0.159 22
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:0097708 Not Cancer Driver No 96 0.13 514 64 0.125 0
ECE1 ECE1 P42892 Endothelin-converting enzyme 1 chr1 GO:0097708 Not Cancer Driver No 118 0.153 99 26 0.263 1
ECPAS_ENST00000338205 ECPAS Q5VYK3 Proteasome adapter and scaffold protein ECM29 chr9 GO:0097708 Not Cancer Driver No 176 0.095 240 22 0.092 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0097708 Not Cancer Driver No 37 0.175 97 20 0.206 3
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0097708 Census, Compendium Yes 444 0.367 223 35 0.157 1
ELANE_ENST00000263621 ELANE P08246 Neutrophil elastase chr19 GO:0097708 Not Cancer Driver No 39 0.146 18 3 0.167 89
F5 F5 P12259 Coagulation factor V chr1 GO:0097708 Not Cancer Driver No 455 0.205 974 223 0.229 7
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0097708 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0097708 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGG FGG P02679 Fibrinogen gamma chain chr4 GO:0097708 Not Cancer Driver No 81 0.179 53 8 0.151 8
FLNB_ENST00000295956 FLNB O75369 Filamin-B chr3 GO:0097708 Not Cancer Driver No 362 0.139 1183 170 0.144 19
FMNL1 FMNL1 O95466 Formin-like protein 1 chr17 GO:0097708 Not Cancer Driver No 115 0.105 524 32 0.061 0
GFRA1 GFRA1 P56159 GDNF family receptor alpha-1 chr10 GO:0097708 Not Cancer Driver No 120 0.258 43 12 0.279 0
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 GO:0097708 Not Cancer Driver No 42 0.119 11 0 0.0 1
GRIPAP1 GRIPAP1 Q4V328 GRIP1-associated protein 1 chrX GO:0097708 Not Cancer Driver No 110 0.131 725 99 0.137 0
GSN GSN P06396 Gelsolin chr9 GO:0097708 Not Cancer Driver No 76 0.097 316 28 0.089 2
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0097708 Not Cancer Driver No 178 0.147 409 59 0.144 0
HEXA_ENST00000268097 HEXA P06865 Beta-hexosaminidase subunit alpha chr15 GO:0097708 Not Cancer Driver No 59 0.112 5 1 0.2 49
HEXB HEXB P07686 Beta-hexosaminidase subunit beta chr5 GO:0097708 Not Cancer Driver No 45 0.081 0 0 0.0 9
HPS4_ENST00000336873 HPS4 Q9NQG7 Hermansky-Pudlak syndrome 4 protein chr22 GO:0097708 Not Cancer Driver No 96 0.136 343 57 0.166 0
HRG HRG P04196 Histidine-rich glycoprotein chr3 GO:0097708 Not Cancer Driver No 121 0.23 277 75 0.271 2
IFT172 IFT172 Q9UG01 Intraflagellar transport protein 172 homolog chr2 GO:0097708 Not Cancer Driver No 219 0.125 96 10 0.104 8
INPP5F INPP5F Q9Y2H2 Phosphatidylinositide phosphatase SAC2 chr10 GO:0097708 Not Cancer Driver No 138 0.122 394 45 0.114 0
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0097708 Census Yes 153 0.146 92 9 0.098 0
ITGB5 ITGB5 P18084 Integrin beta-5 chr3 GO:0097708 Not Cancer Driver No 86 0.108 27 3 0.111 0
ITSN1 ITSN1 Q15811 Intersectin-1 chr21 GO:0097708 Not Cancer Driver No 214 0.124 797 107 0.134 0
ITSN2 ITSN2 Q9NZM3 Intersectin-2 chr2 GO:0097708 Not Cancer Driver No 207 0.122 680 92 0.135 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0097708 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIF1A_ENST00000320389 KIF1A Q12756 Kinesin-like protein KIF1A chr2 GO:0097708 Not Cancer Driver No 275 0.163 594 79 0.133 35
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 GO:0097708 Census, Compendium Yes 122 0.127 586 67 0.114 0
KLK5_ENST00000593428 KLK5 Q9Y337 Kallikrein-5 chr19 GO:0097708 Not Cancer Driver No 69 0.235 75 16 0.213 0
KLK7 KLK7 P49862 Kallikrein-7 chr19 GO:0097708 Not Cancer Driver No 43 0.17 38 8 0.211 0
KRTDAP KRTDAP P60985 Keratinocyte differentiation-associated protein chr19 GO:0097708 Not Cancer Driver No 19 0.192 19 3 0.158 0
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 GO:0097708 Not Cancer Driver No 47 0.113 93 10 0.108 0
LAPTM4B_ENST00000619747 LAPTM4B Q86VI4 Lysosomal-associated transmembrane protein 4B chr8 GO:0097708 Not Cancer Driver No 24 0.076 73 5 0.068 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0097708 Not Cancer Driver No 119 0.138 63 3 0.048 104
LMBRD1 LMBRD1 Q9NUN5 Lysosomal cobalamin transport escort protein LMBD1 chr6 GO:0097708 Not Cancer Driver No 90 0.167 31 3 0.097 0
LRAT LRAT O95237 Lecithin retinol acyltransferase chr4 GO:0097708 Not Cancer Driver No 54 0.235 2 0 0.0 1
LRIG2 LRIG2 O94898 Leucine-rich repeats and immunoglobulin-like domains protein 2 chr1 GO:0097708 Not Cancer Driver No 131 0.123 231 30 0.13 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0097708 Not Cancer Driver No 519 0.205 90 17 0.189 23
LTF LTF P02788 Lactotransferrin chr3 GO:0097708 Not Cancer Driver No 131 0.185 21 4 0.19 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0097708 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMRN1 MMRN1 Q13201 Multimerin-1 chr4 GO:0097708 Not Cancer Driver No 241 0.196 373 75 0.201 0
MPEG1 MPEG1 Q2M385 Macrophage-expressed gene 1 protein chr11 GO:0097708 Not Cancer Driver No 134 0.187 101 21 0.208 0
MPO MPO P05164 Myeloperoxidase chr17 GO:0097708 Not Cancer Driver No 149 0.2 52 12 0.231 3
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0097708 Census, Compendium Yes 379 0.149 296 37 0.125 18
MYH9 MYH9 P35579 Myosin-9 chr22 GO:0097708 Census, Compendium Yes 310 0.158 1120 160 0.143 17
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 GO:0097708 Not Cancer Driver No 110 0.103 66 11 0.167 0
MYO1E MYO1E Q12965 Unconventional myosin-Ie chr15 GO:0097708 Not Cancer Driver No 137 0.124 229 14 0.061 1
MYO5A MYO5A Q9Y4I1 Unconventional myosin-Va chr15 GO:0097708 Census, Compendium Yes 224 0.121 497 58 0.117 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 GO:0097708 Not Cancer Driver No 176 0.136 342 41 0.12 3
MYRIP MYRIP Q8NFW9 Rab effector MyRIP chr3 GO:0097708 Not Cancer Driver No 133 0.155 599 95 0.159 0
NAPSA NAPSA O96009 Napsin-A chr19 GO:0097708 Not Cancer Driver No 58 0.138 14 1 0.071 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0097708 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCF2 NCF2 P19878 Neutrophil cytosol factor 2 chr1 GO:0097708 Not Cancer Driver No 97 0.184 183 34 0.186 14
NCF4_ENST00000248899 NCF4 Q15080 Neutrophil cytosol factor 4 chr22 GO:0097708 Not Cancer Driver No 60 0.177 27 4 0.148 1
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 GO:0097708 Not Cancer Driver No 126 0.129 463 60 0.13 4
NLRP5 NLRP5 P59047 NACHT, LRR and PYD domains-containing protein 5 chr19 GO:0097708 Not Cancer Driver No 369 0.307 144 35 0.243 0
NME8_ENST00000440017 NME8 Q8N427 Thioredoxin domain-containing protein 3 chr7 GO:0097708 Not Cancer Driver No 178 0.303 87 44 0.506 0
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0097708 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0097708 Not Cancer Driver No 169 0.163 40 4 0.1 15
NPY_ENST00000405982 NPY P01303 Pro-neuropeptide Y chr7 GO:0097708 Not Cancer Driver No 29 0.299 43 19 0.442 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0097708 Compendium Yes 146 0.158 211 31 0.147 0
NSG1_ENST00000513555 NSG1 P42857 Neuronal vesicle trafficking-associated protein 1 chr4 GO:0097708 Not Cancer Driver No 36 0.195 29 9 0.31 0
OLFM4 OLFM4 Q6UX06 Olfactomedin-4 chr13 GO:0097708 Not Cancer Driver No 117 0.229 54 11 0.204 0
OPRD1 OPRD1 P41143 Delta-type opioid receptor chr1 GO:0097708 Not Cancer Driver No 91 0.245 30 3 0.1 0
PADI6 PADI6 Q6TGC4 Protein-arginine deiminase type-6 chr1 GO:0097708 Not Cancer Driver No 101 0.146 27 5 0.185 2
PDIA3 PDIA3 P30101 Protein disulfide-isomerase A3 chr15 GO:0097708 Not Cancer Driver No 57 0.113 98 11 0.112 0
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0097708 Census Yes 89 0.137 320 42 0.131 0
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 GO:0097708 Not Cancer Driver No 50 0.12 49 3 0.061 0
PITHD1 PITHD1 Q9GZP4 PITH domain-containing protein 1 chr1 GO:0097708 Not Cancer Driver No 26 0.123 119 11 0.092 0
PLA2G5 PLA2G5 P39877 Phospholipase A2 group V chr1 GO:0097708 Not Cancer Driver No 24 0.174 0 0 0.0 2
PLAT PLAT P00750 Tissue-type plasminogen activator chr8 GO:0097708 Not Cancer Driver No 89 0.158 15 2 0.133 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0097708 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLD4_ENST00000392593 PLD4 Q96BZ4 5'-3' exonuclease PLD4 chr14 GO:0097708 Not Cancer Driver No 46 0.091 76 10 0.132 0
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 GO:0097708 Census, Compendium Yes 39 0.102 66 11 0.167 17
PRKAR1B_ENST00000403562 PRKAR1B P31321 cAMP-dependent protein kinase type I-beta regulatory subunit chr7 GO:0097708 Not Cancer Driver No 53 0.139 71 13 0.183 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0097708 Compendium Yes 79 0.117 43 9 0.209 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0097708 Not Cancer Driver No 110 0.237 78 15 0.192 31
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0097708 Not Cancer Driver No 49 0.113 140 25 0.179 0
RAB10 RAB10 P61026 Ras-related protein Rab-10 chr2 GO:0097708 Not Cancer Driver No 19 0.095 28 2 0.071 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 GO:0097708 Not Cancer Driver No 31 0.144 43 4 0.093 0
RAB11B RAB11B Q15907 Ras-related protein Rab-11B chr19 GO:0097708 Not Cancer Driver No 26 0.119 39 3 0.077 2
RAB11FIP5 RAB11FIP5 Q9BXF6 Rab11 family-interacting protein 5 chr2 GO:0097708 Not Cancer Driver No 83 0.127 533 70 0.131 0
RAB12 RAB12 Q6IQ22 Ras-related protein Rab-12 chr18 GO:0097708 Not Cancer Driver No 22 0.09 72 3 0.042 0
RAB13 RAB13 P51153 Ras-related protein Rab-13 chr1 GO:0097708 Not Cancer Driver No 19 0.094 40 0 0.0 0
RAB14 RAB14 P61106 Ras-related protein Rab-14 chr9 GO:0097708 Not Cancer Driver No 20 0.093 41 4 0.098 0
RAB15 RAB15 P59190 Ras-related protein Rab-15 chr14 GO:0097708 Not Cancer Driver No 18 0.085 50 5 0.1 0
RAB20 RAB20 Q9NX57 Ras-related protein Rab-20 chr13 GO:0097708 Not Cancer Driver No 33 0.141 57 8 0.14 0
RAB22A RAB22A Q9UL26 Ras-related protein Rab-22A chr20 GO:0097708 Not Cancer Driver No 23 0.119 23 4 0.174 0
RAB23_ENST00000317483 RAB23 Q9ULC3 Ras-related protein Rab-23 chr6 GO:0097708 Not Cancer Driver No 28 0.118 62 6 0.097 2
RAB27A_ENST00000336787 RAB27A P51159 Ras-related protein Rab-27A chr15 GO:0097708 Not Cancer Driver No 25 0.113 15 4 0.267 3
RAB29 RAB29 O14966 Ras-related protein Rab-7L1 chr1 GO:0097708 Not Cancer Driver No 28 0.138 18 3 0.167 0
RAB31 RAB31 Q13636 Ras-related protein Rab-31 chr18 GO:0097708 Not Cancer Driver No 27 0.139 28 11 0.393 0
RAB32 RAB32 Q13637 Ras-related protein Rab-32 chr6 GO:0097708 Not Cancer Driver No 18 0.08 40 2 0.05 0
RAB34_ENST00000436730 RAB34 Q9BZG1 Ras-related protein Rab-34 chr17 GO:0097708 Not Cancer Driver No 41 0.158 1 0 0.0 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 GO:0097708 Not Cancer Driver No 25 0.124 25 2 0.08 0
RAB38 RAB38 P57729 Ras-related protein Rab-38 chr11 GO:0097708 Not Cancer Driver No 27 0.128 0 0 0.0 0
RAB39A RAB39A Q14964 Ras-related protein Rab-39A chr11 GO:0097708 Not Cancer Driver No 29 0.134 3 0 0.0 0
RAB3D_ENST00000589655 RAB3D O95716 Ras-related protein Rab-3D chr19 GO:0097708 Not Cancer Driver No 37 0.169 46 6 0.13 0
RAB3IL1 RAB3IL1 Q8TBN0 Guanine nucleotide exchange factor for Rab-3A chr11 GO:0097708 Not Cancer Driver No 41 0.107 217 18 0.083 0
RAB3IP RAB3IP Q96QF0 Rab-3A-interacting protein chr12 GO:0097708 Not Cancer Driver No 85 0.179 227 33 0.145 0
RAB43_ENST00000393305 RAB43 Q86YS6 Ras-related protein Rab-43 chr3 GO:0097708 Not Cancer Driver No 26 0.123 14 0 0.0 0
RAB4A RAB4A P20338 Ras-related protein Rab-4A chr1 GO:0097708 Not Cancer Driver No 26 0.119 32 11 0.344 0
RAB4B_ENST00000357052 RAB4B P61018 Ras-related protein Rab-4B chr19 GO:0097708 Not Cancer Driver No 40 0.188 36 10 0.278 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 GO:0097708 Not Cancer Driver No 32 0.149 65 15 0.231 0
RAB6A_ENST00000336083 RAB6A P20340 Ras-related protein Rab-6A chr11 GO:0097708 Not Cancer Driver No 22 0.106 45 6 0.133 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 GO:0097708 Not Cancer Driver No 27 0.13 11 0 0.0 4
RAB8A RAB8A P61006 Ras-related protein Rab-8A chr19 GO:0097708 Not Cancer Driver No 37 0.179 26 3 0.115 0
RAB8B RAB8B Q92930 Ras-related protein Rab-8B chr15 GO:0097708 Not Cancer Driver No 22 0.106 29 2 0.069 0
RAB9A RAB9A P51151 Ras-related protein Rab-9A chrX GO:0097708 Not Cancer Driver No 18 0.09 21 1 0.048 0
RAB9B RAB9B Q9NP90 Ras-related protein Rab-9B chrX GO:0097708 Not Cancer Driver No 43 0.214 11 3 0.273 0
SCG2 SCG2 P13521 Secretogranin-2 chr2 GO:0097708 Not Cancer Driver No 116 0.188 531 103 0.194 0
SCIMP SCIMP Q6UWF3 SLP adapter and CSK-interacting membrane protein chr17 GO:0097708 Not Cancer Driver No 10 0.069 73 9 0.123 0
SERPINA5_ENST00000554276 SERPINA5 P05154 Plasma serine protease inhibitor chr14 GO:0097708 Not Cancer Driver No 103 0.254 24 17 0.708 0
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 GO:0097708 Not Cancer Driver No 62 0.156 0 0 0.0 0
SFTA3 SFTA3 P0C7M3 Surfactant-associated protein 3 chr14 GO:0097708 Not Cancer Driver No 22 0.234 13 2 0.154 0
SFTPA1_ENST00000398636 SFTPA1 Q8IWL2 Pulmonary surfactant-associated protein A1 chr10 GO:0097708 Not Cancer Driver No 41 0.165 171 33 0.193 3
SFTPA2 SFTPA2 Q8IWL1 Pulmonary surfactant-associated protein A2 chr10 GO:0097708 Not Cancer Driver No 53 0.214 174 43 0.247 7
SFTPB_ENST00000519937 SFTPB P07988 Pulmonary surfactant-associated protein B chr2 GO:0097708 Not Cancer Driver No 57 0.15 37 6 0.162 1
SFTPC SFTPC P11686 Pulmonary surfactant-associated protein C chr8 GO:0097708 Not Cancer Driver No 21 0.107 19 2 0.105 5
SFTPD SFTPD P35247 Pulmonary surfactant-associated protein D chr10 GO:0097708 Not Cancer Driver No 66 0.176 274 53 0.193 0
SH3GL3_ENST00000427482 SH3GL3 Q99963 Endophilin-A3 chr15 GO:0097708 Not Cancer Driver No 88 0.254 83 23 0.277 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0097708 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLC17A8 SLC17A8 Q8NDX2 Vesicular glutamate transporter 3 chr12 GO:0097708 Not Cancer Driver No 134 0.228 95 30 0.316 1
SLC2A4 SLC2A4 P14672 Solute carrier family 2, facilitated glucose transporter member 4 chr17 GO:0097708 Not Cancer Driver No 71 0.139 43 8 0.186 1
SLC5A1 SLC5A1 P13866 Sodium/glucose cotransporter 1 chr22 GO:0097708 Not Cancer Driver No 104 0.157 47 2 0.043 22
SLC6A5 SLC6A5 Q9Y345 Sodium- and chloride-dependent glycine transporter 2 chr11 GO:0097708 Not Cancer Driver No 181 0.227 169 38 0.225 7
SLC6A9 SLC6A9 P48067 Sodium- and chloride-dependent glycine transporter 1 chr1 GO:0097708 Not Cancer Driver No 102 0.144 65 12 0.185 1
SMPD1 SMPD1 P17405 Sphingomyelin phosphodiesterase chr11 GO:0097708 Not Cancer Driver No 93 0.147 51 4 0.078 111
SNAP23 SNAP23 O00161 Synaptosomal-associated protein 23 chr15 GO:0097708 Not Cancer Driver No 18 0.085 179 16 0.089 0
SNX3 SNX3 O60493 Sorting nexin-3 chr6 GO:0097708 Not Cancer Driver No 21 0.13 37 4 0.108 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0097708 Not Cancer Driver No 16 0.104 93 9 0.097 79
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0097708 Not Cancer Driver No 374 0.169 87 10 0.115 0
SPARC SPARC P09486 SPARC chr5 GO:0097708 Not Cancer Driver No 60 0.198 69 5 0.072 2
SPINK5_ENST00000256084 SPINK5 Q9NQ38 Serine protease inhibitor Kazal-type 5 chr5 GO:0097708 Not Cancer Driver No 168 0.158 590 102 0.173 0
SPX SPX Q9BT56 Spexin chr12 GO:0097708 Not Cancer Driver No 22 0.19 40 8 0.2 0
SRGAP2 SRGAP2 O75044 SLIT-ROBO Rho GTPase-activating protein 2 chr1 GO:0097708 Not Cancer Driver No 122 0.114 541 71 0.131 0
STEAP3_ENST00000393107 STEAP3 Q658P3 Metalloreductase STEAP3 chr2 GO:0097708 Not Cancer Driver No 82 0.168 30 2 0.067 0
STX12 STX12 Q86Y82 Syntaxin-12 chr1 GO:0097708 Not Cancer Driver No 21 0.076 156 9 0.058 0
STX3 STX3 Q13277 Syntaxin-3 chr11 GO:0097708 Not Cancer Driver No 51 0.176 129 30 0.233 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0097708 Not Cancer Driver No 50 0.168 152 20 0.132 0
STX6 STX6 O43752 Syntaxin-6 chr1 GO:0097708 Not Cancer Driver No 33 0.129 78 11 0.141 0
STX7 STX7 O15400 Syntaxin-7 chr6 GO:0097708 Not Cancer Driver No 29 0.111 164 14 0.085 0
STX8 STX8 Q9UNK0 Syntaxin-8 chr17 GO:0097708 Not Cancer Driver No 32 0.136 98 10 0.102 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0097708 Not Cancer Driver No 97 0.163 111 23 0.207 18
STXBP2_ENST00000221283 STXBP2 Q15833 Syntaxin-binding protein 2 chr19 GO:0097708 Not Cancer Driver No 77 0.13 80 13 0.163 5
STXBP3 STXBP3 O00186 Syntaxin-binding protein 3 chr1 GO:0097708 Not Cancer Driver No 59 0.1 64 9 0.141 0
STXBP4 STXBP4 Q6ZWJ1 Syntaxin-binding protein 4 chr17 GO:0097708 Not Cancer Driver No 78 0.141 211 24 0.114 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0097708 Census Yes 96 0.151 131 27 0.206 5
SYT11 SYT11 Q9BT88 Synaptotagmin-11 chr1 GO:0097708 Not Cancer Driver No 64 0.148 105 23 0.219 0
SYT1_ENST00000393240 SYT1 P21579 Synaptotagmin-1 chr12 GO:0097708 Not Cancer Driver No 104 0.246 103 36 0.35 5
SYT2_ENST00000367268 SYT2 Q8N9I0 Synaptotagmin-2 chr1 GO:0097708 Not Cancer Driver No 73 0.174 141 24 0.17 3
SYT4 SYT4 Q9H2B2 Synaptotagmin-4 chr18 GO:0097708 Not Cancer Driver No 111 0.261 107 41 0.383 0
SYT5 SYT5 O00445 Synaptotagmin-5 chr19 GO:0097708 Not Cancer Driver No 60 0.155 110 11 0.1 0
SYT7_ENST00000263846 SYT7 O43581 Synaptotagmin-7 chr11 GO:0097708 Not Cancer Driver No 63 0.156 132 25 0.189 0
SYT8 SYT8 Q8NBV8 Synaptotagmin-8 chr11 GO:0097708 Not Cancer Driver No 41 0.102 129 22 0.171 0
SYT9 SYT9 Q86SS6 Synaptotagmin-9 chr11 GO:0097708 Not Cancer Driver No 120 0.244 148 42 0.284 0
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0097708 Not Cancer Driver No 188 0.161 320 58 0.181 0
THBS2 THBS2 P35442 Thrombospondin-2 chr6 GO:0097708 Not Cancer Driver No 246 0.21 319 68 0.213 0
TLR7 TLR7 Q9NYK1 Toll-like receptor 7 chrX GO:0097708 Not Cancer Driver No 182 0.173 14 1 0.071 1
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0097708 Not Cancer Driver No 141 0.137 35 3 0.086 0
TPCN1_ENST00000335509 TPCN1 Q9ULQ1 Two pore channel protein 1 chr12 GO:0097708 Not Cancer Driver No 114 0.14 99 18 0.182 0
TPT1_ENST00000530705 TPT1 P13693 Translationally-controlled tumor protein chr13 GO:0097708 Not Cancer Driver No 17 0.099 43 6 0.14 0
TREML1 TREML1 Q86YW5 Trem-like transcript 1 protein chr6 GO:0097708 Not Cancer Driver No 35 0.113 136 19 0.14 0
TRIM14 TRIM14 Q14142 Tripartite motif-containing protein 14 chr9 GO:0097708 Not Cancer Driver No 36 0.081 93 7 0.075 0
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 GO:0097708 Not Cancer Driver No 46 0.118 159 23 0.145 0
TYRP1 TYRP1 P17643 5,6-dihydroxyindole-2-carboxylic acid oxidase chr9 GO:0097708 Not Cancer Driver No 81 0.151 87 13 0.149 2
UNC13D UNC13D Q70J99 Protein unc-13 homolog D chr17 GO:0097708 Not Cancer Driver No 120 0.11 248 30 0.121 0
UNC93B1 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 GO:0097708 Not Cancer Driver No 57 0.095 127 5 0.039 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0097708 Not Cancer Driver No 89 0.127 243 28 0.115 0
VAMP7_ENST00000286448 VAMP7 P51809 Vesicle-associated membrane protein 7 chrX GO:0097708 Not Cancer Driver No 38 0.173 4 1 0.25 0
VAMP8 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 GO:0097708 Not Cancer Driver No 9 0.09 27 0 0.0 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 GO:0097708 Not Cancer Driver No 84 0.18 316 57 0.18 1
VPS26B VPS26B Q4G0F5 Vacuolar protein sorting-associated protein 26B chr11 GO:0097708 Not Cancer Driver No 45 0.134 52 5 0.096 0
VPS33B VPS33B Q9H267 Vacuolar protein sorting-associated protein 33B chr15 GO:0097708 Not Cancer Driver No 54 0.088 17 0 0.0 2
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0097708 Not Cancer Driver No 68 0.085 99 9 0.091 1
VTA1 VTA1 Q9NP79 Vacuolar protein sorting-associated protein VTA1 homolog chr6 GO:0097708 Not Cancer Driver No 49 0.16 152 25 0.164 0
VWF VWF P04275 von Willebrand factor chr12 GO:0097708 Not Cancer Driver No 456 0.162 91 16 0.176 43
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0097708 Census, Compendium Yes 75 0.149 400 55 0.138 30
ZDHHC2 ZDHHC2 Q9UIJ5 Palmitoyltransferase ZDHHC2 chr8 GO:0097708 Not Cancer Driver No 47 0.128 73 6 0.082 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 GO:0097708 Not Cancer Driver No 89 0.124 462 63 0.136 0
ZP2 ZP2 Q05996 Zona pellucida sperm-binding protein 2 chr16 GO:0097708 Not Cancer Driver No 129 0.173 65 14 0.215 0
ZYX ZYX Q15942 Zyxin chr7 GO:0097708 Not Cancer Driver No 83 0.145 385 52 0.135 0