Total number of protein in "GO:0097193" GO term: 71
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AIFM1 | AIFM1 | O95831 | Apoptosis-inducing factor 1, mitochondrial | chrX | GO:0097193 | Not Cancer Driver | No | 88 | 0.144 | 166 | 22 | 0.133 | 11 |
| APAF1 | APAF1 | O14727 | Apoptotic protease-activating factor 1 | chr12 | GO:0097193 | Not Cancer Driver | No | 127 | 0.102 | 17 | 1 | 0.059 | 0 |
| APOPT1 | COA8 | Q96IL0 | Cytochrome c oxidase assembly factor 8 | chr14 | GO:0097193 | Not Cancer Driver | No | 23 | 0.112 | 48 | 4 | 0.083 | 0 |
| ARL6IP5 | ARL6IP5 | O75915 | PRA1 family protein 3 | chr3 | GO:0097193 | Not Cancer Driver | No | 26 | 0.138 | 0 | 0 | 0.0 | 0 |
| ATF2 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0097193 | Not Cancer Driver | No | 65 | 0.129 | 451 | 58 | 0.129 | 0 |
| ATF4_ENST00000404241 | ATF4 | P18848 | Cyclic AMP-dependent transcription factor ATF-4 | chr22 | GO:0097193 | Not Cancer Driver | No | 53 | 0.151 | 259 | 38 | 0.147 | 0 |
| ATP2A1 | ATP2A1 | O14983 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | chr16 | GO:0097193 | Not Cancer Driver | No | 157 | 0.157 | 80 | 11 | 0.138 | 1 |
| ATP2A3_ENST00000397041 | ATP2A3 | Q93084 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | chr17 | GO:0097193 | Not Cancer Driver | No | 130 | 0.13 | 147 | 16 | 0.109 | 0 |
| BAD_ENST00000309032 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | GO:0097193 | Not Cancer Driver | No | 14 | 0.083 | 163 | 14 | 0.086 | 0 |
| BAG6 | BAG6 | P46379 | Large proline-rich protein BAG6 | chr6 | GO:0097193 | Not Cancer Driver | No | 98 | 0.087 | 861 | 79 | 0.092 | 0 |
| BAK1 | BAK1 | Q16611 | Bcl-2 homologous antagonist/killer | chr6 | GO:0097193 | Not Cancer Driver | No | 38 | 0.18 | 58 | 9 | 0.155 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0097193 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BBC3 | BBC3 | Q96PG8 | Bcl-2-binding component 3, isoforms 3/4 | chr19 | GO:0097193 | Not Cancer Driver | No | 20 | 0.077 | 253 | 20 | 0.079 | 0 |
| BCL2_ENST00000333681 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0097193 | Census, Compendium | Yes | 24 | 0.1 | 72 | 5 | 0.069 | 0 |
| BRSK2_ENST00000528841 | BRSK2 | Q8IWQ3 | Serine/threonine-protein kinase BRSK2 | chr11 | GO:0097193 | Not Cancer Driver | No | 90 | 0.122 | 321 | 39 | 0.121 | 0 |
| CASP3 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0097193 | Census | Yes | 32 | 0.116 | 62 | 5 | 0.081 | 0 |
| CASP4 | CASP4 | P49662 | Caspase-4 | chr11 | GO:0097193 | Not Cancer Driver | No | 56 | 0.149 | 102 | 14 | 0.137 | 0 |
| CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0097193 | Census, Compendium | Yes | 48 | 0.293 | 121 | 30 | 0.248 | 0 |
| CEBPB | CEBPB | P17676 | CCAAT/enhancer-binding protein beta | chr20 | GO:0097193 | Not Cancer Driver | No | 3 | 0.009 | 276 | 2 | 0.007 | 0 |
| CHAC1_ENST00000617961 | CHAC1 | Q9BUX1 | Glutathione-specific gamma-glutamylcyclotransferase 1 | chr15 | GO:0097193 | Not Cancer Driver | No | 30 | 0.135 | 49 | 5 | 0.102 | 0 |
| CUL1_ENST00000602748 | CUL1 | Q13616 | Cullin-1 | chr7 | GO:0097193 | Not Cancer Driver | No | 151 | 0.195 | 65 | 9 | 0.138 | 0 |
| CUL2_ENST00000374748 | CUL2 | Q13617 | Cullin-2 | chr10 | GO:0097193 | Not Cancer Driver | No | 87 | 0.117 | 66 | 3 | 0.045 | 0 |
| CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | GO:0097193 | Census, Compendium | Yes | 123 | 0.16 | 167 | 23 | 0.138 | 3 |
| CUL4A | CUL4A | Q13619 | Cullin-4A | chr13 | GO:0097193 | Not Cancer Driver | No | 64 | 0.084 | 102 | 2 | 0.02 | 0 |
| CUL5 | CUL5 | Q93034 | Cullin-5 | chr11 | GO:0097193 | Not Cancer Driver | No | 97 | 0.124 | 5 | 1 | 0.2 | 0 |
| CYP1B1 | CYP1B1 | Q16678 | Cytochrome P450 1B1 | chr2 | GO:0097193 | Not Cancer Driver | No | 61 | 0.112 | 31 | 3 | 0.097 | 40 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0097193 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
| DDIT3_ENST00000623876 | DDIT3 | P35638 | DNA damage-inducible transcript 3 protein | chr12 | GO:0097193 | Census | Yes | 29 | 0.172 | 160 | 27 | 0.169 | 0 |
| DDX3X_ENST00000629496 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:0097193 | Census, Compendium | Yes | 133 | 0.201 | 301 | 47 | 0.156 | 18 |
| DIABLO | DIABLO | Q9NR28 | Diablo IAP-binding mitochondrial protein | chr12 | GO:0097193 | Not Cancer Driver | No | 62 | 0.259 | 54 | 8 | 0.148 | 1 |
| DNAJC10 | DNAJC10 | Q8IXB1 | DnaJ homolog subfamily C member 10 | chr2 | GO:0097193 | Not Cancer Driver | No | 110 | 0.139 | 36 | 3 | 0.083 | 0 |
| ERN1 | ERN1 | O75460 | Serine/threonine-protein kinase/endoribonuclease IRE1 | chr17 | GO:0097193 | Not Cancer Driver | No | 125 | 0.128 | 250 | 28 | 0.112 | 0 |
| ERN2 | ERN2 | Q76MJ5 | Serine/threonine-protein kinase/endoribonuclease IRE2 | chr16 | GO:0097193 | Not Cancer Driver | No | 192 | 0.207 | 213 | 45 | 0.211 | 0 |
| ERO1A | ERO1A | Q96HE7 | ERO1-like protein alpha | chr14 | GO:0097193 | Not Cancer Driver | No | 48 | 0.103 | 32 | 5 | 0.156 | 0 |
| GPX1_ENST00000620890 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0097193 | Not Cancer Driver | No | 38 | 0.187 | 12 | 1 | 0.083 | 0 |
| GSKIP_ENST00000438650 | GSKIP | Q9P0R6 | GSK3B-interacting protein | chr14 | GO:0097193 | Not Cancer Driver | No | 11 | 0.079 | 32 | 1 | 0.031 | 0 |
| HIPK2 | HIPK2 | Q9H2X6 | Homeodomain-interacting protein kinase 2 | chr7 | GO:0097193 | Not Cancer Driver | No | 154 | 0.129 | 686 | 96 | 0.14 | 0 |
| HRAS | HRAS | P01112 | GTPase HRas | chr11 | GO:0097193 | Census, Compendium | Yes | 107 | 0.566 | 16 | 4 | 0.25 | 18 |
| IFI6_ENST00000361157 | IFI6 | P09912 | Interferon alpha-inducible protein 6 | chr1 | GO:0097193 | Not Cancer Driver | No | 12 | 0.092 | 7 | 0 | 0.0 | 0 |
| ITPR1_ENST00000354582 | ITPR1 | Q14643 | Inositol 1,4,5-trisphosphate receptor type 1 | chr3 | GO:0097193 | Not Cancer Driver | No | 390 | 0.141 | 581 | 76 | 0.131 | 6 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0097193 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
| LGALS12_ENST00000394618 | LGALS12 | Q96DT0 | Galectin-12 | chr11 | GO:0097193 | Not Cancer Driver | No | 49 | 0.146 | 8 | 2 | 0.25 | 0 |
| MAP3K5 | MAP3K5 | Q99683 | Mitogen-activated protein kinase kinase kinase 5 | chr6 | GO:0097193 | Not Cancer Driver | No | 197 | 0.143 | 242 | 29 | 0.12 | 0 |
| MELK | MELK | Q14680 | Maternal embryonic leucine zipper kinase | chr9 | GO:0097193 | Not Cancer Driver | No | 76 | 0.117 | 162 | 24 | 0.148 | 0 |
| MLLT11 | MLLT11 | Q13015 | Protein AF1q | chr1 | GO:0097193 | Census | Yes | 15 | 0.167 | 18 | 5 | 0.278 | 0 |
| MSH6 | MSH6 | P52701 | DNA mismatch repair protein Msh6 | chr2 | GO:0097193 | Census | Yes | 154 | 0.113 | 386 | 41 | 0.106 | 6 |
| NBN | NBN | O60934 | Nibrin | chr8 | GO:0097193 | Census | Yes | 90 | 0.119 | 417 | 54 | 0.129 | 1 |
| NOL3_ENST00000268605 | NOL3 | O60936 | Nucleolar protein 3 | chr16 | GO:0097193 | Not Cancer Driver | No | 20 | 0.096 | 179 | 17 | 0.095 | 2 |
| PDCD10_ENST00000473645 | PDCD10 | Q9BUL8 | Programmed cell death protein 10 | chr3 | GO:0097193 | Not Cancer Driver | No | 32 | 0.151 | 25 | 4 | 0.16 | 0 |
| PDK1_ENST00000282077 | PDK1 | Q15118 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | chr2 | GO:0097193 | Not Cancer Driver | No | 52 | 0.119 | 50 | 10 | 0.2 | 0 |
| PMAIP1 | PMAIP1 | Q13794 | Phorbol-12-myristate-13-acetate-induced protein 1 | chr18 | GO:0097193 | Not Cancer Driver | No | 2 | 0.037 | 23 | 1 | 0.043 | 0 |
| PML | PML | P29590 | Protein PML | chr15 | GO:0097193 | Census, Compendium | Yes | 112 | 0.127 | 312 | 34 | 0.109 | 0 |
| PPM1F | PPM1F | P49593 | Protein phosphatase 1F | chr22 | GO:0097193 | Not Cancer Driver | No | 53 | 0.117 | 242 | 24 | 0.099 | 0 |
| PPP1R15A | PPP1R15A | O75807 | Protein phosphatase 1 regulatory subunit 15A | chr19 | GO:0097193 | Not Cancer Driver | No | 83 | 0.123 | 628 | 72 | 0.115 | 0 |
| PRKCD_ENST00000330452 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | GO:0097193 | Compendium | Yes | 79 | 0.117 | 43 | 9 | 0.209 | 0 |
| PRODH_ENST00000610940 | PRODH | O43272 | Proline dehydrogenase 1, mitochondrial | chr22 | GO:0097193 | Not Cancer Driver | No | 62 | 0.103 | 67 | 8 | 0.119 | 16 |
| QRICH1_ENST00000357496 | QRICH1 | Q2TAL8 | Transcriptional regulator QRICH1 | chr3 | GO:0097193 | Not Cancer Driver | No | 93 | 0.12 | 423 | 55 | 0.13 | 0 |
| RNF186 | RNF186 | Q9NXI6 | E3 ubiquitin-protein ligase RNF186 | chr1 | GO:0097193 | Not Cancer Driver | No | 27 | 0.119 | 11 | 3 | 0.273 | 0 |
| SCN2A_ENST00000637266 | SCN2A | Q99250 | Sodium channel protein type 2 subunit alpha | chr2 | GO:0097193 | Not Cancer Driver | No | 502 | 0.25 | 435 | 133 | 0.306 | 65 |
| SELENOK | SELENOK | Q9Y6D0 | Selenoprotein K | chr3 | GO:0097193 | Not Cancer Driver | No | 10 | 0.106 | 47 | 6 | 0.128 | 0 |
| SGPP1 | SGPP1 | Q9BX95 | Sphingosine-1-phosphate phosphatase 1 | chr14 | GO:0097193 | Not Cancer Driver | No | 48 | 0.109 | 116 | 1 | 0.009 | 0 |
| SOD2_ENST00000367055 | SOD2 | P04179 | Superoxide dismutase [Mn], mitochondrial | chr6 | GO:0097193 | Not Cancer Driver | No | 32 | 0.144 | 25 | 5 | 0.2 | 0 |
| STK24 | STK24 | Q9Y6E0 | Serine/threonine-protein kinase 24 | chr13 | GO:0097193 | Not Cancer Driver | No | 67 | 0.151 | 118 | 16 | 0.136 | 0 |
| STK25 | STK25 | O00506 | Serine/threonine-protein kinase 25 | chr2 | GO:0097193 | Not Cancer Driver | No | 42 | 0.099 | 170 | 15 | 0.088 | 0 |
| TMBIM6_ENST00000549385 | TMBIM6 | P55061 | Bax inhibitor 1 | chr12 | GO:0097193 | Not Cancer Driver | No | 16 | 0.068 | 3 | 0 | 0.0 | 0 |
| TMEM117 | TMEM117 | Q9H0C3 | Transmembrane protein 117 | chr12 | GO:0097193 | Not Cancer Driver | No | 91 | 0.177 | 70 | 12 | 0.171 | 0 |
| TNFRSF10B | TNFRSF10B | O14763 | Tumor necrosis factor receptor superfamily member 10B | chr8 | GO:0097193 | Not Cancer Driver | No | 44 | 0.1 | 190 | 19 | 0.1 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0097193 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TRAF2 | TRAF2 | Q12933 | TNF receptor-associated factor 2 | chr9 | GO:0097193 | Not Cancer Driver | No | 63 | 0.126 | 4 | 1 | 0.25 | 0 |
| TRIB3_ENST00000217233 | TRIB3 | Q96RU7 | Tribbles homolog 3 | chr20 | GO:0097193 | Not Cancer Driver | No | 65 | 0.182 | 114 | 24 | 0.211 | 0 |
| ZNF622 | ZNF622 | Q969S3 | Zinc finger protein 622 | chr5 | GO:0097193 | Not Cancer Driver | No | 66 | 0.138 | 220 | 33 | 0.15 | 0 |