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Total number of protein in "GO:0097190" GO term:  114

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0097190 Not Cancer Driver No 64 0.196 12 4 0.333 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0097190 Not Cancer Driver No 88 0.144 166 22 0.133 11
ANXA6 ANXA6 P08133 Annexin A6 chr5 GO:0097190 Not Cancer Driver No 95 0.141 107 15 0.14 0
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0097190 Not Cancer Driver No 127 0.102 17 1 0.059 0
ARL6IP5 ARL6IP5 O75915 PRA1 family protein 3 chr3 GO:0097190 Not Cancer Driver No 26 0.138 0 0 0.0 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0097190 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0097190 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 GO:0097190 Not Cancer Driver No 157 0.157 80 11 0.138 1
ATP2A3_ENST00000397041 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 GO:0097190 Not Cancer Driver No 130 0.13 147 16 0.109 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0097190 Not Cancer Driver No 98 0.087 861 79 0.092 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0097190 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0097190 Census Yes 30 0.156 39 2 0.051 0
BBC3 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 GO:0097190 Not Cancer Driver No 20 0.077 253 20 0.079 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0097190 Census, Compendium Yes 24 0.1 72 5 0.069 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0097190 Not Cancer Driver No 90 0.122 321 39 0.121 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0097190 Census, Compendium Yes 147 0.223 114 27 0.237 110
CASP1 CASP1 P29466 Caspase-1 chr11 GO:0097190 Not Cancer Driver No 79 0.196 87 18 0.207 0
CASP10_ENST00000272879 CASP10 Q92851 Caspase-10 chr2 GO:0097190 Not Cancer Driver No 57 0.109 126 17 0.135 3
CASP12 CASP12 Q6UXS9 Inactive caspase-12 chr11 GO:0097190 Not Cancer Driver No 12 0.035 31 1 0.032 0
CASP2 CASP2 P42575 Caspase-2 chr7 GO:0097190 Not Cancer Driver No 63 0.139 42 12 0.286 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0097190 Census Yes 32 0.116 62 5 0.081 0
CASP4 CASP4 P49662 Caspase-4 chr11 GO:0097190 Not Cancer Driver No 56 0.149 102 14 0.137 0
CASP5_ENST00000260315 CASP5 P51878 Caspase-5 chr11 GO:0097190 Not Cancer Driver No 103 0.237 61 17 0.279 0
CASP8AP2 CASP8AP2 Q9UKL3 CASP8-associated protein 2 chr6 GO:0097190 Not Cancer Driver No 219 0.11 1501 178 0.119 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0097190 Census, Compendium Yes 142 0.296 106 12 0.113 1
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0097190 Not Cancer Driver No 30 0.169 2 0 0.0 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0097190 Census Yes 42 0.191 18 10 0.556 0
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0097190 Not Cancer Driver No 54 0.18 3 1 0.333 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0097190 Not Cancer Driver No 28 0.135 72 12 0.167 0
CD5 CD5 P06127 T-cell surface glycoprotein CD5 chr11 GO:0097190 Not Cancer Driver No 67 0.135 146 19 0.13 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0097190 Not Cancer Driver No 3 0.009 276 2 0.007 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0097190 Not Cancer Driver No 40 0.083 44 2 0.045 0
CHAC1_ENST00000617961 CHAC1 Q9BUX1 Glutathione-specific gamma-glutamylcyclotransferase 1 chr15 GO:0097190 Not Cancer Driver No 30 0.135 49 5 0.102 0
CRADD_ENST00000332896 CRADD P78560 Death domain-containing protein CRADD chr12 GO:0097190 Not Cancer Driver No 35 0.176 45 5 0.111 1
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0097190 Not Cancer Driver No 61 0.112 31 3 0.097 40
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0097190 Not Cancer Driver No 131 0.11 681 68 0.1 0
DAP3_ENST00000343043 DAP3 P51398 28S ribosomal protein S29, mitochondrial chr1 GO:0097190 Not Cancer Driver No 58 0.146 82 14 0.171 0
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 GO:0097190 Not Cancer Driver No 193 0.135 114 11 0.096 0
DAPK3_ENST00000301264 DAPK3 O43293 Death-associated protein kinase 3 chr19 GO:0097190 Not Cancer Driver No 56 0.123 82 7 0.085 0
DAPL1 DAPL1 A0PJW8 Death-associated protein-like 1 chr2 GO:0097190 Not Cancer Driver No 9 0.084 67 5 0.075 0
DAP_ENST00000230895 DAP P51397 Death-associated protein 1 chr5 GO:0097190 Not Cancer Driver No 10 0.098 102 10 0.098 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0097190 Census Yes 29 0.172 160 27 0.169 0
DIABLO DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 GO:0097190 Not Cancer Driver No 62 0.259 54 8 0.148 1
DIDO1 DIDO1 Q9BTC0 Death-inducer obliterator 1 chr20 GO:0097190 Not Cancer Driver No 453 0.202 1917 400 0.209 0
DNAJC10 DNAJC10 Q8IXB1 DnaJ homolog subfamily C member 10 chr2 GO:0097190 Not Cancer Driver No 110 0.139 36 3 0.083 0
DPF2_ENST00000528416 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 GO:0097190 Not Cancer Driver No 67 0.171 179 30 0.168 5
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0097190 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0097190 Not Cancer Driver No 192 0.207 213 45 0.211 0
ERO1A ERO1A Q96HE7 ERO1-like protein alpha chr14 GO:0097190 Not Cancer Driver No 48 0.103 32 5 0.156 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0097190 Not Cancer Driver No 26 0.125 45 10 0.222 1
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 GO:0097190 Not Cancer Driver No 65 0.231 94 18 0.191 1
FASTK FASTK Q14296 Fas-activated serine/threonine kinase chr7 GO:0097190 Not Cancer Driver No 65 0.118 143 12 0.084 0
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 GO:0097190 Census, Compendium Yes 173 0.215 241 26 0.108 37
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0097190 Not Cancer Driver No 38 0.187 12 1 0.083 0
GSKIP_ENST00000438650 GSKIP Q9P0R6 GSK3B-interacting protein chr14 GO:0097190 Not Cancer Driver No 11 0.079 32 1 0.031 0
HIP1 HIP1 O00291 Huntingtin-interacting protein 1 chr7 GO:0097190 Census, Compendium Yes 137 0.132 510 70 0.137 0
IFI27L1 IFI27L1 Q96BM0 Interferon alpha-inducible protein 27-like protein 1 chr14 GO:0097190 Not Cancer Driver No 8 0.077 3 0 0.0 0
IFI27L2 IFI27L2 Q9H2X8 Interferon alpha-inducible protein 27-like protein 2 chr14 GO:0097190 Not Cancer Driver No 18 0.138 39 4 0.103 0
IFI27_ENST00000621160 IFI27 P40305 Interferon alpha-inducible protein 27, mitochondrial chr14 GO:0097190 Not Cancer Driver No 10 0.082 0 0 0.0 0
IFI6_ENST00000361157 IFI6 P09912 Interferon alpha-inducible protein 6 chr1 GO:0097190 Not Cancer Driver No 12 0.092 7 0 0.0 0
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 GO:0097190 Not Cancer Driver No 191 0.166 133 12 0.09 0
ITPR1_ENST00000354582 ITPR1 Q14643 Inositol 1,4,5-trisphosphate receptor type 1 chr3 GO:0097190 Not Cancer Driver No 390 0.141 581 76 0.131 6
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0097190 Census, Compendium Yes 136 0.12 59 5 0.085 5
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0097190 Not Cancer Driver No 197 0.143 242 29 0.12 0
MELK MELK Q14680 Maternal embryonic leucine zipper kinase chr9 GO:0097190 Not Cancer Driver No 76 0.117 162 24 0.148 0
METTL21C METTL21C Q5VZV1 Protein-lysine methyltransferase METTL21C chr13 GO:0097190 Not Cancer Driver No 54 0.205 47 13 0.277 0
MOAP1_ENST00000298894 MOAP1 Q96BY2 Modulator of apoptosis 1 chr14 GO:0097190 Not Cancer Driver No 48 0.137 47 8 0.17 0
NDUFA13 NDUFA13 Q9P0J0 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 chr19 GO:0097190 Not Cancer Driver No 29 0.201 24 4 0.167 1
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0097190 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0097190 Not Cancer Driver No 51 0.086 14 2 0.143 0
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:0097190 Not Cancer Driver No 35 0.103 327 33 0.101 0
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0097190 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDCD6 PDCD6 O75340 Programmed cell death protein 6 chr5 GO:0097190 Not Cancer Driver No 21 0.11 24 1 0.042 0
PDK1_ENST00000282077 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 GO:0097190 Not Cancer Driver No 52 0.119 50 10 0.2 0
PML PML P29590 Protein PML chr15 GO:0097190 Census, Compendium Yes 112 0.127 312 34 0.109 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0097190 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0097190 Not Cancer Driver No 83 0.123 628 72 0.115 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0097190 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0097190 Compendium Yes 79 0.117 43 9 0.209 0
PRODH_ENST00000610940 PRODH O43272 Proline dehydrogenase 1, mitochondrial chr22 GO:0097190 Not Cancer Driver No 62 0.103 67 8 0.119 16
PTGIS PTGIS Q16647 Prostacyclin synthase chr20 GO:0097190 Not Cancer Driver No 102 0.204 18 3 0.167 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0097190 Not Cancer Driver No 19 0.165 60 10 0.167 2
QRICH1_ENST00000357496 QRICH1 Q2TAL8 Transcriptional regulator QRICH1 chr3 GO:0097190 Not Cancer Driver No 93 0.12 423 55 0.13 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0097190 Not Cancer Driver No 66 0.127 295 39 0.132 0
RNF186 RNF186 Q9NXI6 E3 ubiquitin-protein ligase RNF186 chr1 GO:0097190 Not Cancer Driver No 27 0.119 11 3 0.273 0
SCN2A_ENST00000637266 SCN2A Q99250 Sodium channel protein type 2 subunit alpha chr2 GO:0097190 Not Cancer Driver No 502 0.25 435 133 0.306 65
SELENOK SELENOK Q9Y6D0 Selenoprotein K chr3 GO:0097190 Not Cancer Driver No 10 0.106 47 6 0.128 0
SENP1 SENP1 Q9P0U3 Sentrin-specific protease 1 chr12 GO:0097190 Not Cancer Driver No 64 0.099 355 44 0.124 0
SGPL1 SGPL1 O95470 Sphingosine-1-phosphate lyase 1 chr10 GO:0097190 Not Cancer Driver No 68 0.12 19 3 0.158 2
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0097190 Not Cancer Driver No 56 0.121 139 14 0.101 81
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0097190 Not Cancer Driver No 32 0.144 25 5 0.2 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0097190 Not Cancer Driver No 46 0.17 187 34 0.182 0
SST SST P61278 Somatostatin chr3 GO:0097190 Not Cancer Driver No 25 0.216 40 15 0.375 0
SSTR3 SSTR3 P32745 Somatostatin receptor type 3 chr22 GO:0097190 Not Cancer Driver No 94 0.225 110 26 0.236 0
ST20_ENST00000562759 ST20 Q9HBF5 Suppressor of tumorigenicity 20 protein chr15 GO:0097190 Not Cancer Driver No 17 0.215 0 0 0.0 0
STK24 STK24 Q9Y6E0 Serine/threonine-protein kinase 24 chr13 GO:0097190 Not Cancer Driver No 67 0.151 118 16 0.136 0
STK25 STK25 O00506 Serine/threonine-protein kinase 25 chr2 GO:0097190 Not Cancer Driver No 42 0.099 170 15 0.088 0
TFPT TFPT P0C1Z6 TCF3 fusion partner chr19 GO:0097190 Census Yes 41 0.162 237 41 0.173 0
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0097190 Not Cancer Driver No 92 0.129 443 66 0.149 1
TM2D1_ENST00000294613 TM2D1 Q9BX74 TM2 domain-containing protein 1 chr1 GO:0097190 Not Cancer Driver No 28 0.135 11 5 0.455 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:0097190 Not Cancer Driver No 16 0.068 3 0 0.0 0
TMEM117 TMEM117 Q9H0C3 Transmembrane protein 117 chr12 GO:0097190 Not Cancer Driver No 91 0.177 70 12 0.171 0
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 GO:0097190 Not Cancer Driver No 55 0.118 174 17 0.098 0
TNFRSF10B TNFRSF10B O14763 Tumor necrosis factor receptor superfamily member 10B chr8 GO:0097190 Not Cancer Driver No 44 0.1 190 19 0.1 0
TNFRSF10C TNFRSF10C O14798 Tumor necrosis factor receptor superfamily member 10C chr8 GO:0097190 Not Cancer Driver No 47 0.181 120 30 0.25 0
TNFRSF25_ENST00000356876 TNFRSF25 Q93038 Tumor necrosis factor receptor superfamily member 25 chr1 GO:0097190 Not Cancer Driver No 38 0.091 72 6 0.083 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0097190 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0097190 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRIB3_ENST00000217233 TRIB3 Q96RU7 Tribbles homolog 3 chr20 GO:0097190 Not Cancer Driver No 65 0.182 114 24 0.211 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0097190 Not Cancer Driver No 24 0.212 28 8 0.286 0
UACA UACA Q9BZF9 Uveal autoantigen with coiled-coil domains and ankyrin repeats chr15 GO:0097190 Not Cancer Driver No 177 0.125 863 101 0.117 0
UBE4B UBE4B O95155 Ubiquitin conjugation factor E4 B chr1 GO:0097190 Not Cancer Driver No 158 0.121 434 49 0.113 0
ZDHHC3_ENST00000424952 ZDHHC3 Q9NYG2 Palmitoyltransferase ZDHHC3 chr3 GO:0097190 Not Cancer Driver No 31 0.104 0 0 0.0 0
ZNF622 ZNF622 Q969S3 Zinc finger protein 622 chr5 GO:0097190 Not Cancer Driver No 66 0.138 220 33 0.15 0