Total number of protein in "GO:0090559" GO term: 63
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACAA2 | ACAA2 | P42765 | 3-ketoacyl-CoA thiolase, mitochondrial | chr18 | GO:0090559 | Not Cancer Driver | No | 42 | 0.106 | 51 | 2 | 0.039 | 0 |
| ALKBH7 | ALKBH7 | Q9BT30 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial | chr19 | GO:0090559 | Not Cancer Driver | No | 21 | 0.095 | 28 | 1 | 0.036 | 0 |
| ARHGAP11B | ARHGAP11B | Q3KRB8 | Inactive Rho GTPase-activating protein 11B | chr15 | GO:0090559 | Not Cancer Driver | No | 20 | 0.075 | 17 | 1 | 0.059 | 0 |
| ATF2 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0090559 | Not Cancer Driver | No | 65 | 0.129 | 451 | 58 | 0.129 | 0 |
| ATP5IF1 | ATP5IF1 | Q9UII2 | ATPase inhibitor, mitochondrial | chr1 | GO:0090559 | Not Cancer Driver | No | 8 | 0.075 | 85 | 7 | 0.082 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0090559 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BBC3 | BBC3 | Q96PG8 | Bcl-2-binding component 3, isoforms 3/4 | chr19 | GO:0090559 | Not Cancer Driver | No | 20 | 0.077 | 253 | 20 | 0.079 | 0 |
| BCL2L11 | BCL2L11 | O43521 | Bcl-2-like protein 11 | chr2 | GO:0090559 | Not Cancer Driver | No | 42 | 0.212 | 130 | 17 | 0.131 | 0 |
| BCL2L2 | BCL2L2 | Q92843 | Bcl-2-like protein 2 | chr14 | GO:0090559 | Not Cancer Driver | No | 22 | 0.114 | 34 | 6 | 0.176 | 0 |
| BID_ENST00000551952 | BID | P55957 | BH3-interacting domain death agonist | chr22 | GO:0090559 | Not Cancer Driver | No | 23 | 0.118 | 74 | 9 | 0.122 | 0 |
| BLOC1S2 | BLOC1S2 | Q6QNY1 | Biogenesis of lysosome-related organelles complex 1 subunit 2 | chr10 | GO:0090559 | Not Cancer Driver | No | 17 | 0.12 | 34 | 6 | 0.176 | 0 |
| BNIP3L | BNIP3L | O60238 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like | chr8 | GO:0090559 | Not Cancer Driver | No | 16 | 0.073 | 175 | 14 | 0.08 | 0 |
| BOK | BOK | Q9UMX3 | Bcl-2-related ovarian killer protein | chr2 | GO:0090559 | Not Cancer Driver | No | 7 | 0.033 | 0 | 0 | 0.0 | 0 |
| CAMK2A_ENST00000348628 | CAMK2A | Q9UQM7 | Calcium/calmodulin-dependent protein kinase type II subunit alpha | chr5 | GO:0090559 | Not Cancer Driver | No | 83 | 0.174 | 62 | 10 | 0.161 | 7 |
| CHCHD10_ENST00000484558 | CHCHD10 | Q8WYQ3 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial | chr22 | GO:0090559 | Not Cancer Driver | No | 8 | 0.056 | 97 | 4 | 0.041 | 4 |
| CLDN3 | CLDN3 | O15551 | Claudin-3 | chr7 | GO:0090559 | Not Cancer Driver | No | 12 | 0.055 | 0 | 0 | 0.0 | 0 |
| DEFA5 | DEFA5 | Q01523 | Defensin-5 | chr8 | GO:0090559 | Not Cancer Driver | No | 16 | 0.17 | 17 | 3 | 0.176 | 0 |
| EYA2 | EYA2 | O00167 | Eyes absent homolog 2 | chr20 | GO:0090559 | Not Cancer Driver | No | 107 | 0.199 | 204 | 50 | 0.245 | 0 |
| F11R | F11R | Q9Y624 | Junctional adhesion molecule A | chr1 | GO:0090559 | Not Cancer Driver | No | 47 | 0.157 | 72 | 15 | 0.208 | 0 |
| FZD9 | FZD9 | O00144 | Frizzled-9 | chr7 | GO:0090559 | Not Cancer Driver | No | 55 | 0.093 | 61 | 0 | 0.0 | 0 |
| GCLC | GCLC | P48506 | Glutamate--cysteine ligase catalytic subunit | chr6 | GO:0090559 | Not Cancer Driver | No | 73 | 0.115 | 167 | 18 | 0.108 | 3 |
| GSK3A | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | GO:0090559 | Not Cancer Driver | No | 55 | 0.114 | 180 | 8 | 0.044 | 0 |
| GSK3B_ENST00000264235 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0090559 | Not Cancer Driver | No | 56 | 0.133 | 146 | 13 | 0.089 | 0 |
| GZMB | GZMB | P10144 | Granzyme B | chr14 | GO:0090559 | Not Cancer Driver | No | 49 | 0.198 | 103 | 23 | 0.223 | 0 |
| HEBP2 | HEBP2 | Q9Y5Z4 | Heme-binding protein 2 | chr6 | GO:0090559 | Not Cancer Driver | No | 20 | 0.098 | 113 | 12 | 0.106 | 0 |
| HEG1 | HEG1 | Q9ULI3 | Protein HEG homolog 1 | chr3 | GO:0090559 | Not Cancer Driver | No | 173 | 0.125 | 974 | 135 | 0.139 | 0 |
| HIP1R | HIP1R | O75146 | Huntingtin-interacting protein 1-related protein | chr12 | GO:0090559 | Not Cancer Driver | No | 94 | 0.088 | 524 | 34 | 0.065 | 0 |
| HK2 | HK2 | P52789 | Hexokinase-2 | chr2 | GO:0090559 | Not Cancer Driver | No | 138 | 0.15 | 77 | 7 | 0.091 | 0 |
| HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | GO:0090559 | Not Cancer Driver | No | 24 | 0.037 | 200 | 13 | 0.065 | 0 |
| JAM3 | JAM3 | Q9BX67 | Junctional adhesion molecule C | chr11 | GO:0090559 | Not Cancer Driver | No | 50 | 0.161 | 62 | 11 | 0.177 | 2 |
| LAPTM4B_ENST00000619747 | LAPTM4B | Q86VI4 | Lysosomal-associated transmembrane protein 4B | chr8 | GO:0090559 | Not Cancer Driver | No | 24 | 0.076 | 73 | 5 | 0.068 | 0 |
| LAPTM5 | LAPTM5 | Q13571 | Lysosomal-associated transmembrane protein 5 | chr1 | GO:0090559 | Not Cancer Driver | No | 46 | 0.176 | 16 | 6 | 0.375 | 0 |
| MAPK8_ENST00000374189 | MAPK8 | P45983 | Mitogen-activated protein kinase 8 | chr10 | GO:0090559 | Not Cancer Driver | No | 64 | 0.15 | 94 | 9 | 0.096 | 0 |
| MPV17L | MPV17L | Q2QL34 | Mpv17-like protein | chr16 | GO:0090559 | Not Cancer Driver | No | 16 | 0.082 | 3 | 0 | 0.0 | 0 |
| MT3 | MT3 | P25713 | Metallothionein-3 | chr16 | GO:0090559 | Not Cancer Driver | No | 7 | 0.103 | 0 | 0 | 0.0 | 0 |
| MTOR | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0090559 | Census, Compendium | Yes | 379 | 0.149 | 296 | 37 | 0.125 | 18 |
| MTRNR2L5 | MTRNR2L5 | P0CJ72 | Humanin-like 5 | chr10 | GO:0090559 | Not Cancer Driver | No | 1 | 0.042 | 0 | 0 | 0.0 | 0 |
| MUL1 | MUL1 | Q969V5 | Mitochondrial ubiquitin ligase activator of NFKB 1 | chr1 | GO:0090559 | Not Cancer Driver | No | 48 | 0.136 | 16 | 2 | 0.125 | 0 |
| NAIF1 | NAIF1 | Q69YI7 | Nuclear apoptosis-inducing factor 1 | chr9 | GO:0090559 | Not Cancer Driver | No | 46 | 0.141 | 219 | 27 | 0.123 | 0 |
| NMT1_ENST00000258960 | NMT1 | P30419 | Glycylpeptide N-tetradecanoyltransferase 1 | chr17 | GO:0090559 | Not Cancer Driver | No | 62 | 0.125 | 169 | 22 | 0.13 | 0 |
| NOL3_ENST00000268605 | NOL3 | O60936 | Nucleolar protein 3 | chr16 | GO:0090559 | Not Cancer Driver | No | 20 | 0.096 | 179 | 17 | 0.095 | 2 |
| PDCD6IP_ENST00000307296 | PDCD6IP | Q8WUM4 | Programmed cell death 6-interacting protein | chr3 | GO:0090559 | Not Cancer Driver | No | 85 | 0.098 | 272 | 22 | 0.081 | 0 |
| PPIF | PPIF | P30405 | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | chr10 | GO:0090559 | Not Cancer Driver | No | 19 | 0.092 | 43 | 4 | 0.093 | 0 |
| RASIP1 | RASIP1 | Q5U651 | Ras-interacting protein 1 | chr19 | GO:0090559 | Not Cancer Driver | No | 73 | 0.076 | 505 | 48 | 0.095 | 0 |
| RHOT1_ENST00000333942 | RHOT1 | Q8IXI2 | Mitochondrial Rho GTPase 1 | chr17 | GO:0090559 | Not Cancer Driver | No | 56 | 0.091 | 46 | 2 | 0.043 | 0 |
| RHOT2 | RHOT2 | Q8IXI1 | Mitochondrial Rho GTPase 2 | chr16 | GO:0090559 | Not Cancer Driver | No | 52 | 0.084 | 79 | 5 | 0.063 | 0 |
| RTL10_ENST00000407472 | RTL10 | Q7L3V2 | Protein Bop | chr22 | GO:0090559 | Not Cancer Driver | No | 52 | 0.143 | 196 | 31 | 0.158 | 0 |
| SLC25A31 | SLC25A31 | Q9H0C2 | ADP/ATP translocase 4 | chr4 | GO:0090559 | Not Cancer Driver | No | 68 | 0.216 | 8 | 0 | 0.0 | 0 |
| SLC25A4 | SLC25A4 | P12235 | ADP/ATP translocase 1 | chr4 | GO:0090559 | Not Cancer Driver | No | 24 | 0.081 | 0 | 0 | 0.0 | 9 |
| SLC25A5 | SLC25A5 | P05141 | ADP/ATP translocase 2 | chrX | GO:0090559 | Not Cancer Driver | No | 41 | 0.138 | 0 | 0 | 0.0 | 0 |
| SLC25A6 | SLC25A6 | P12236 | ADP/ATP translocase 3 | chrX | GO:0090559 | Not Cancer Driver | No | 41 | 0.138 | 0 | 0 | 0.0 | 0 |
| SLC35F6 | SLC35F6 | Q8N357 | Solute carrier family 35 member F6 | chr2 | GO:0090559 | Not Cancer Driver | No | 33 | 0.089 | 13 | 0 | 0.0 | 0 |
| SLC9A1 | SLC9A1 | P19634 | Sodium/hydrogen exchanger 1 | chr1 | GO:0090559 | Not Cancer Driver | No | 89 | 0.109 | 251 | 29 | 0.116 | 1 |
| SPG7 | SPG7 | Q9UQ90 | Paraplegin | chr16 | GO:0090559 | Not Cancer Driver | No | 97 | 0.122 | 181 | 29 | 0.16 | 4 |
| STPG1 | STPG1 | Q5TH74 | O(6)-methylguanine-induced apoptosis 2 | chr1 | GO:0090559 | Not Cancer Driver | No | 45 | 0.135 | 171 | 23 | 0.135 | 0 |
| THEM4 | THEM4 | Q5T1C6 | Acyl-coenzyme A thioesterase THEM4 | chr1 | GO:0090559 | Not Cancer Driver | No | 19 | 0.079 | 14 | 0 | 0.0 | 0 |
| TJP2_ENST00000377245 | TJP2 | Q9UDY2 | Tight junction protein ZO-2 | chr9 | GO:0090559 | Not Cancer Driver | No | 149 | 0.125 | 919 | 113 | 0.123 | 1 |
| TMEM102 | TMEM102 | Q8N9M5 | Transmembrane protein 102 | chr17 | GO:0090559 | Not Cancer Driver | No | 38 | 0.075 | 141 | 13 | 0.092 | 0 |
| TMEM14A | TMEM14A | Q9Y6G1 | Transmembrane protein 14A | chr6 | GO:0090559 | Not Cancer Driver | No | 10 | 0.101 | 0 | 0 | 0.0 | 0 |
| TMIGD1 | TMIGD1 | Q6UXZ0 | Transmembrane and immunoglobulin domain-containing protein 1 | chr17 | GO:0090559 | Not Cancer Driver | No | 37 | 0.141 | 6 | 1 | 0.167 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0090559 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| VDAC2_ENST00000543351 | VDAC2 | P45880 | Voltage-dependent anion-selective channel protein 2 | chr10 | GO:0090559 | Not Cancer Driver | No | 35 | 0.119 | 9 | 1 | 0.111 | 0 |
| ZNF205_ENST00000382192 | ZNF205 | O95201 | Zinc finger protein 205 | chr16 | GO:0090559 | Not Cancer Driver | No | 74 | 0.134 | 367 | 49 | 0.134 | 0 |