Total number of protein in "GO:0090305" GO term: 166
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABT1 | ABT1 | Q9ULW3 | Activator of basal transcription 1 | chr6 | GO:0090305 | Not Cancer Driver | No | 56 | 0.206 | 157 | 30 | 0.191 | 0 |
| AEN | AEN | Q8WTP8 | Apoptosis-enhancing nuclease | chr15 | GO:0090305 | Not Cancer Driver | No | 39 | 0.12 | 183 | 21 | 0.115 | 0 |
| ALKBH1 | ALKBH1 | Q13686 | Nucleic acid dioxygenase ALKBH1 | chr14 | GO:0090305 | Not Cancer Driver | No | 55 | 0.141 | 77 | 11 | 0.143 | 0 |
| ANGEL1 | ANGEL1 | Q9UNK9 | Protein angel homolog 1 | chr14 | GO:0090305 | Not Cancer Driver | No | 85 | 0.127 | 160 | 21 | 0.131 | 0 |
| ANGEL2 | ANGEL2 | Q5VTE6 | Protein angel homolog 2 | chr1 | GO:0090305 | Not Cancer Driver | No | 56 | 0.103 | 48 | 6 | 0.125 | 0 |
| ANKRD31 | ANKRD31 | Q8N7Z5 | Ankyrin repeat domain-containing protein 31 | chr5 | GO:0090305 | Not Cancer Driver | No | 62 | 0.033 | 1144 | 34 | 0.03 | 0 |
| APEX2 | APEX2 | Q9UBZ4 | DNA-(apurinic or apyrimidinic site) endonuclease 2 | chrX | GO:0090305 | Not Cancer Driver | No | 66 | 0.127 | 148 | 14 | 0.095 | 0 |
| APLF | APLF | Q8IW19 | Aprataxin and PNK-like factor | chr2 | GO:0090305 | Not Cancer Driver | No | 64 | 0.125 | 407 | 57 | 0.14 | 0 |
| APTX_ENST00000379819 | APTX | Q7Z2E3 | Aprataxin | chr9 | GO:0090305 | Not Cancer Driver | No | 36 | 0.101 | 101 | 6 | 0.059 | 9 |
| ASTE1_ENST00000264992 | ASTE1 | Q2TB18 | Protein asteroid homolog 1 | chr3 | GO:0090305 | Not Cancer Driver | No | 82 | 0.121 | 40 | 4 | 0.1 | 0 |
| ATAD5 | ATAD5 | Q96QE3 | ATPase family AAA domain-containing protein 5 | chr17 | GO:0090305 | Not Cancer Driver | No | 200 | 0.108 | 1075 | 112 | 0.104 | 0 |
| BOP1 | BOP1 | Q14137 | Ribosome biogenesis protein BOP1 | chr8 | GO:0090305 | Not Cancer Driver | No | 20 | 0.027 | 304 | 19 | 0.062 | 0 |
| C12orf10 | MYG1 | Q9HB07 | MYG1 exonuclease | chr12 | GO:0090305 | Not Cancer Driver | No | 30 | 0.08 | 95 | 9 | 0.095 | 0 |
| CECR2_ENST00000342247 | CECR2 | Q9BXF3 | Cat eye syndrome critical region protein 2 | chr22 | GO:0090305 | Not Cancer Driver | No | 222 | 0.15 | 1192 | 183 | 0.154 | 0 |
| CNOT1 | CNOT1 | A5YKK6 | CCR4-NOT transcription complex subunit 1 | chr16 | GO:0090305 | Not Cancer Driver | No | 346 | 0.146 | 464 | 56 | 0.121 | 12 |
| CNOT2 | CNOT2 | Q9NZN8 | CCR4-NOT transcription complex subunit 2 | chr12 | GO:0090305 | Not Cancer Driver | No | 84 | 0.156 | 354 | 66 | 0.186 | 0 |
| CNOT6L | CNOT6L | Q96LI5 | CCR4-NOT transcription complex subunit 6-like | chr4 | GO:0090305 | Not Cancer Driver | No | 58 | 0.105 | 37 | 3 | 0.081 | 0 |
| CNOT6_ENST00000261951 | CNOT6 | Q9ULM6 | CCR4-NOT transcription complex subunit 6 | chr5 | GO:0090305 | Not Cancer Driver | No | 65 | 0.117 | 66 | 4 | 0.061 | 0 |
| CNOT7 | CNOT7 | Q9UIV1 | CCR4-NOT transcription complex subunit 7 | chr8 | GO:0090305 | Not Cancer Driver | No | 31 | 0.109 | 21 | 1 | 0.048 | 0 |
| CNOT8 | CNOT8 | Q9UFF9 | CCR4-NOT transcription complex subunit 8 | chr5 | GO:0090305 | Not Cancer Driver | No | 30 | 0.103 | 6 | 0 | 0.0 | 0 |
| CPSF1 | CPSF1 | Q10570 | Cleavage and polyadenylation specificity factor subunit 1 | chr8 | GO:0090305 | Not Cancer Driver | No | 177 | 0.123 | 298 | 42 | 0.141 | 0 |
| CPSF2 | CPSF2 | Q9P2I0 | Cleavage and polyadenylation specificity factor subunit 2 | chr14 | GO:0090305 | Not Cancer Driver | No | 76 | 0.097 | 231 | 22 | 0.095 | 0 |
| CPSF3 | CPSF3 | Q9UKF6 | Cleavage and polyadenylation specificity factor subunit 3 | chr2 | GO:0090305 | Not Cancer Driver | No | 78 | 0.114 | 56 | 9 | 0.161 | 0 |
| CPSF4 | CPSF4 | O95639 | Cleavage and polyadenylation specificity factor subunit 4 | chr7 | GO:0090305 | Not Cancer Driver | No | 36 | 0.134 | 89 | 11 | 0.124 | 0 |
| CPSF4L | CPSF4L | A6NMK7 | Putative cleavage and polyadenylation specificity factor subunit 4-like protein | chr17 | GO:0090305 | Not Cancer Driver | No | 7 | 0.039 | 0 | 0 | 0.0 | 0 |
| CPSF6_ENST00000435070 | CPSF6 | Q16630 | Cleavage and polyadenylation specificity factor subunit 6 | chr12 | GO:0090305 | Not Cancer Driver | No | 85 | 0.154 | 484 | 75 | 0.155 | 0 |
| CPSF7_ENST00000394888 | CPSF7 | Q8N684 | Cleavage and polyadenylation specificity factor subunit 7 | chr11 | GO:0090305 | Not Cancer Driver | No | 55 | 0.117 | 398 | 52 | 0.131 | 0 |
| CSTF2T | CSTF2T | Q9H0L4 | Cleavage stimulation factor subunit 2 tau variant | chr10 | GO:0090305 | Not Cancer Driver | No | 87 | 0.141 | 507 | 75 | 0.148 | 0 |
| CSTF2_ENST00000372972 | CSTF2 | P33240 | Cleavage stimulation factor subunit 2 | chrX | GO:0090305 | Not Cancer Driver | No | 85 | 0.147 | 484 | 72 | 0.149 | 0 |
| CSTF3 | CSTF3 | Q12996 | Cleavage stimulation factor subunit 3 | chr11 | GO:0090305 | Not Cancer Driver | No | 82 | 0.114 | 122 | 15 | 0.123 | 0 |
| DCLRE1A | DCLRE1A | Q6PJP8 | DNA cross-link repair 1A protein | chr10 | GO:0090305 | Not Cancer Driver | No | 92 | 0.088 | 514 | 45 | 0.088 | 0 |
| DCLRE1B | DCLRE1B | Q9H816 | 5' exonuclease Apollo | chr1 | GO:0090305 | Not Cancer Driver | No | 65 | 0.122 | 127 | 17 | 0.134 | 0 |
| DCLRE1C | DCLRE1C | Q96SD1 | Protein artemis | chr10 | GO:0090305 | Not Cancer Driver | No | 76 | 0.11 | 277 | 26 | 0.094 | 3 |
| DCP1A | DCP1A | Q9NPI6 | mRNA-decapping enzyme 1A | chr3 | GO:0090305 | Not Cancer Driver | No | 46 | 0.079 | 382 | 31 | 0.081 | 0 |
| DCP1B | DCP1B | Q8IZD4 | mRNA-decapping enzyme 1B | chr12 | GO:0090305 | Not Cancer Driver | No | 82 | 0.133 | 406 | 63 | 0.155 | 0 |
| DCP2 | DCP2 | Q8IU60 | m7GpppN-mRNA hydrolase | chr5 | GO:0090305 | Not Cancer Driver | No | 57 | 0.136 | 167 | 24 | 0.144 | 0 |
| DCPS | DCPS | Q96C86 | m7GpppX diphosphatase | chr11 | GO:0090305 | Not Cancer Driver | No | 48 | 0.142 | 53 | 6 | 0.113 | 1 |
| DDX1 | DDX1 | Q92499 | ATP-dependent RNA helicase DDX1 | chr2 | GO:0090305 | Not Cancer Driver | No | 82 | 0.111 | 91 | 15 | 0.165 | 0 |
| DFFA | DFFA | O00273 | DNA fragmentation factor subunit alpha | chr1 | GO:0090305 | Not Cancer Driver | No | 47 | 0.142 | 113 | 18 | 0.159 | 0 |
| DFFB_ENST00000378209 | DFFB | O76075 | DNA fragmentation factor subunit beta | chr1 | GO:0090305 | Not Cancer Driver | No | 37 | 0.109 | 27 | 1 | 0.037 | 0 |
| DICER1 | DICER1 | Q9UPY3 | Endoribonuclease Dicer | chr14 | GO:0090305 | Census, Compendium | Yes | 264 | 0.137 | 362 | 45 | 0.124 | 4 |
| DIS3 | DIS3 | Q9Y2L1 | Exosome complex exonuclease RRP44 | chr13 | GO:0090305 | Compendium | Yes | 121 | 0.126 | 235 | 32 | 0.136 | 0 |
| DIS3L | DIS3L | Q8TF46 | DIS3-like exonuclease 1 | chr15 | GO:0090305 | Not Cancer Driver | No | 111 | 0.105 | 139 | 20 | 0.144 | 0 |
| DIS3L2 | DIS3L2 | Q8IYB7 | DIS3-like exonuclease 2 | chr2 | GO:0090305 | Not Cancer Driver | No | 114 | 0.129 | 264 | 22 | 0.083 | 1 |
| DNA2 | DNA2 | P51530 | DNA replication ATP-dependent helicase/nuclease DNA2 | chr10 | GO:0090305 | Not Cancer Driver | No | 120 | 0.113 | 52 | 8 | 0.154 | 3 |
| DNASE1L3 | DNASE1L3 | Q13609 | Deoxyribonuclease gamma | chr3 | GO:0090305 | Not Cancer Driver | No | 43 | 0.141 | 15 | 4 | 0.267 | 0 |
| DNASE2 | DNASE2 | O00115 | Deoxyribonuclease-2-alpha | chr19 | GO:0090305 | Not Cancer Driver | No | 46 | 0.128 | 48 | 7 | 0.146 | 0 |
| DNASE2B | DNASE2B | Q8WZ79 | Deoxyribonuclease-2-beta | chr1 | GO:0090305 | Not Cancer Driver | No | 53 | 0.147 | 14 | 1 | 0.071 | 0 |
| DXO_ENST00000375356 | DXO | O77932 | Decapping and exoribonuclease protein | chr6 | GO:0090305 | Not Cancer Driver | No | 46 | 0.116 | 143 | 17 | 0.119 | 0 |
| EDC3 | EDC3 | Q96F86 | Enhancer of mRNA-decapping protein 3 | chr15 | GO:0090305 | Not Cancer Driver | No | 43 | 0.085 | 185 | 22 | 0.119 | 1 |
| EDC4 | EDC4 | Q6P2E9 | Enhancer of mRNA-decapping protein 4 | chr16 | GO:0090305 | Not Cancer Driver | No | 144 | 0.103 | 702 | 69 | 0.098 | 0 |
| ELAC1 | ELAC1 | Q9H777 | Zinc phosphodiesterase ELAC protein 1 | chr18 | GO:0090305 | Not Cancer Driver | No | 40 | 0.11 | 47 | 4 | 0.085 | 0 |
| ELAC2 | ELAC2 | Q9BQ52 | Zinc phosphodiesterase ELAC protein 2 | chr17 | GO:0090305 | Not Cancer Driver | No | 86 | 0.104 | 208 | 30 | 0.144 | 10 |
| EME1_ENST00000338165 | EME1 | Q96AY2 | Crossover junction endonuclease EME1 | chr17 | GO:0090305 | Not Cancer Driver | No | 56 | 0.098 | 296 | 30 | 0.101 | 0 |
| EME2 | EME2 | A4GXA9 | Probable crossover junction endonuclease EME2 | chr16 | GO:0090305 | Not Cancer Driver | No | 28 | 0.074 | 125 | 7 | 0.056 | 0 |
| ENDOD1 | ENDOD1 | O94919 | Endonuclease domain-containing 1 protein | chr11 | GO:0090305 | Not Cancer Driver | No | 51 | 0.102 | 72 | 9 | 0.125 | 0 |
| ENDOG | ENDOG | Q14249 | Endonuclease G, mitochondrial | chr9 | GO:0090305 | Not Cancer Driver | No | 11 | 0.037 | 61 | 1 | 0.016 | 0 |
| ENPP1 | ENPP1 | P22413 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 | chr6 | GO:0090305 | Not Cancer Driver | No | 148 | 0.16 | 101 | 5 | 0.05 | 33 |
| ENPP2_ENST00000075322 | ENPP2 | Q13822 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | chr8 | GO:0090305 | Not Cancer Driver | No | 168 | 0.195 | 81 | 16 | 0.198 | 0 |
| ENPP3_ENST00000357639 | ENPP3 | O14638 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 | chr6 | GO:0090305 | Not Cancer Driver | No | 146 | 0.167 | 57 | 12 | 0.211 | 0 |
| ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0090305 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
| ERCC4 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:0090305 | Census | Yes | 120 | 0.131 | 225 | 27 | 0.12 | 15 |
| ERCC5 | ERCC5 | P28715 | DNA excision repair protein ERCC-5 | chr13 | GO:0090305 | Census | Yes | 175 | 0.148 | 816 | 121 | 0.148 | 6 |
| ERI1_ENST00000519292 | ERI1 | Q8IV48 | 3'-5' exoribonuclease 1 | chr8 | GO:0090305 | Not Cancer Driver | No | 40 | 0.115 | 78 | 13 | 0.167 | 0 |
| ERI2 | ERI2 | A8K979 | ERI1 exoribonuclease 2 | chr16 | GO:0090305 | Not Cancer Driver | No | 34 | 0.049 | 288 | 8 | 0.028 | 0 |
| ERI3 | ERI3 | O43414 | ERI1 exoribonuclease 3 | chr1 | GO:0090305 | Not Cancer Driver | No | 49 | 0.145 | 29 | 0 | 0.0 | 0 |
| ERN1 | ERN1 | O75460 | Serine/threonine-protein kinase/endoribonuclease IRE1 | chr17 | GO:0090305 | Not Cancer Driver | No | 125 | 0.128 | 250 | 28 | 0.112 | 0 |
| EXD2 | EXD2 | Q9NVH0 | Exonuclease 3'-5' domain-containing protein 2 | chr14 | GO:0090305 | Not Cancer Driver | No | 58 | 0.093 | 176 | 15 | 0.085 | 0 |
| EXD3 | EXD3 | Q8N9H8 | Exonuclease mut-7 homolog | chr9 | GO:0090305 | Not Cancer Driver | No | 103 | 0.118 | 188 | 30 | 0.16 | 0 |
| EXO5_ENST00000358527 | EXO5 | Q9H790 | Exonuclease V | chr1 | GO:0090305 | Not Cancer Driver | No | 39 | 0.105 | 36 | 3 | 0.083 | 0 |
| EXOG | EXOG | Q9Y2C4 | Nuclease EXOG, mitochondrial | chr3 | GO:0090305 | Not Cancer Driver | No | 42 | 0.114 | 52 | 1 | 0.019 | 0 |
| EXOSC10 | EXOSC10 | Q01780 | Exosome component 10 | chr1 | GO:0090305 | Not Cancer Driver | No | 87 | 0.098 | 375 | 35 | 0.093 | 0 |
| EXOSC2 | EXOSC2 | Q13868 | Exosome complex component RRP4 | chr9 | GO:0090305 | Not Cancer Driver | No | 21 | 0.072 | 47 | 6 | 0.128 | 2 |
| EXOSC3 | EXOSC3 | Q9NQT5 | Exosome complex component RRP40 | chr9 | GO:0090305 | Not Cancer Driver | No | 18 | 0.065 | 54 | 2 | 0.037 | 4 |
| EXOSC4 | EXOSC4 | Q9NPD3 | Exosome complex component RRP41 | chr8 | GO:0090305 | Not Cancer Driver | No | 34 | 0.139 | 23 | 0 | 0.0 | 0 |
| EXOSC5 | EXOSC5 | Q9NQT4 | Exosome complex component RRP46 | chr19 | GO:0090305 | Not Cancer Driver | No | 43 | 0.183 | 31 | 3 | 0.097 | 0 |
| EXOSC7 | EXOSC7 | Q15024 | Exosome complex component RRP42 | chr3 | GO:0090305 | Not Cancer Driver | No | 41 | 0.141 | 8 | 1 | 0.125 | 0 |
| EXOSC8 | EXOSC8 | Q96B26 | Exosome complex component RRP43 | chr13 | GO:0090305 | Not Cancer Driver | No | 20 | 0.072 | 28 | 1 | 0.036 | 2 |
| EXOSC9_ENST00000243498 | EXOSC9 | Q06265 | Exosome complex component RRP45 | chr4 | GO:0090305 | Not Cancer Driver | No | 58 | 0.132 | 154 | 18 | 0.117 | 1 |
| FANCM | FANCM | Q8IYD8 | Fanconi anemia group M protein | chr14 | GO:0090305 | Not Cancer Driver | No | 268 | 0.131 | 898 | 128 | 0.143 | 0 |
| FEN1 | FEN1 | P39748 | Flap endonuclease 1 | chr11 | GO:0090305 | Census | Yes | 35 | 0.092 | 111 | 11 | 0.099 | 0 |
| FIP1L1 | FIP1L1 | Q6UN15 | Pre-mRNA 3'-end-processing factor FIP1 | chr4 | GO:0090305 | Census | Yes | 88 | 0.148 | 572 | 85 | 0.149 | 0 |
| FOXL2 | FOXL2 | P58012 | Forkhead box protein L2 | chr3 | GO:0090305 | Census, Compendium | Yes | 39 | 0.104 | 257 | 20 | 0.078 | 26 |
| G3BP1 | G3BP1 | Q13283 | Ras GTPase-activating protein-binding protein 1 | chr5 | GO:0090305 | Not Cancer Driver | No | 85 | 0.182 | 352 | 65 | 0.185 | 0 |
| GEN1_ENST00000381254 | GEN1 | Q17RS7 | Flap endonuclease GEN homolog 1 | chr2 | GO:0090305 | Not Cancer Driver | No | 109 | 0.12 | 339 | 52 | 0.153 | 0 |
| HARBI1 | HARBI1 | Q96MB7 | Putative nuclease HARBI1 | chr11 | GO:0090305 | Not Cancer Driver | No | 40 | 0.115 | 30 | 5 | 0.167 | 0 |
| HMGA2_ENST00000403681 | HMGA2 | P52926 | High mobility group protein HMGI-C | chr12 | GO:0090305 | Census | Yes | 12 | 0.11 | 109 | 12 | 0.11 | 0 |
| ISG20 | ISG20 | Q96AZ6 | Interferon-stimulated gene 20 kDa protein | chr15 | GO:0090305 | Not Cancer Driver | No | 20 | 0.11 | 6 | 0 | 0.0 | 0 |
| ISG20L2 | ISG20L2 | Q9H9L3 | Interferon-stimulated 20 kDa exonuclease-like 2 | chr1 | GO:0090305 | Not Cancer Driver | No | 46 | 0.13 | 232 | 33 | 0.142 | 0 |
| LAS1L | LAS1L | Q9Y4W2 | Ribosomal biogenesis protein LAS1L | chrX | GO:0090305 | Not Cancer Driver | No | 100 | 0.136 | 279 | 49 | 0.176 | 0 |
| MEIOB_ENST00000397344 | MEIOB | Q8N635 | Meiosis-specific with OB domain-containing protein | chr16 | GO:0090305 | Not Cancer Driver | No | 37 | 0.084 | 21 | 2 | 0.095 | 1 |
| MGME1 | MGME1 | Q9BQP7 | Mitochondrial genome maintenance exonuclease 1 | chr20 | GO:0090305 | Not Cancer Driver | No | 33 | 0.096 | 95 | 7 | 0.074 | 1 |
| MRPL44 | MRPL44 | Q9H9J2 | 39S ribosomal protein L44, mitochondrial | chr2 | GO:0090305 | Not Cancer Driver | No | 37 | 0.111 | 45 | 2 | 0.044 | 1 |
| N4BP2 | N4BP2 | Q86UW6 | NEDD4-binding protein 2 | chr4 | GO:0090305 | Census | Yes | 185 | 0.105 | 965 | 104 | 0.108 | 0 |
| NCBP1 | NCBP1 | Q09161 | Nuclear cap-binding protein subunit 1 | chr9 | GO:0090305 | Not Cancer Driver | No | 88 | 0.111 | 89 | 8 | 0.09 | 0 |
| NEIL1_ENST00000564784 | NEIL1 | Q96FI4 | Endonuclease 8-like 1 | chr15 | GO:0090305 | Not Cancer Driver | No | 41 | 0.105 | 165 | 14 | 0.085 | 0 |
| NEIL2 | NEIL2 | Q969S2 | Endonuclease 8-like 2 | chr8 | GO:0090305 | Not Cancer Driver | No | 31 | 0.093 | 145 | 14 | 0.097 | 0 |
| NEIL3 | NEIL3 | Q8TAT5 | Endonuclease 8-like 3 | chr4 | GO:0090305 | Not Cancer Driver | No | 80 | 0.132 | 131 | 18 | 0.137 | 0 |
| NOCT | NOCT | Q9UK39 | Nocturnin | chr4 | GO:0090305 | Not Cancer Driver | No | 33 | 0.077 | 89 | 3 | 0.034 | 0 |
| NOL9 | NOL9 | Q5SY16 | Polynucleotide 5'-hydroxyl-kinase NOL9 | chr1 | GO:0090305 | Not Cancer Driver | No | 73 | 0.104 | 102 | 8 | 0.078 | 0 |
| NOP14 | NOP14 | P78316 | Nucleolar protein 14 | chr4 | GO:0090305 | Not Cancer Driver | No | 87 | 0.102 | 521 | 46 | 0.088 | 0 |
| NOP9 | NOP9 | Q86U38 | Nucleolar protein 9 | chr14 | GO:0090305 | Not Cancer Driver | No | 53 | 0.083 | 166 | 14 | 0.084 | 0 |
| NTHL1 | NTHL1 | P78549 | Endonuclease III-like protein 1 | chr16 | GO:0090305 | Census | Yes | 38 | 0.122 | 147 | 18 | 0.122 | 0 |
| NUDT21 | NUDT21 | O43809 | Cleavage and polyadenylation specificity factor subunit 5 | chr16 | GO:0090305 | Not Cancer Driver | No | 21 | 0.093 | 37 | 3 | 0.081 | 0 |
| PAN2_ENST00000548043 | PAN2 | Q504Q3 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2 | chr12 | GO:0090305 | Not Cancer Driver | No | 139 | 0.116 | 78 | 10 | 0.128 | 0 |
| PAN3 | PAN3 | Q58A45 | PAN2-PAN3 deadenylation complex subunit PAN3 | chr13 | GO:0090305 | Not Cancer Driver | No | 104 | 0.117 | 323 | 35 | 0.108 | 0 |
| PARN | PARN | O95453 | Poly(A)-specific ribonuclease PARN | chr16 | GO:0090305 | Not Cancer Driver | No | 71 | 0.111 | 197 | 22 | 0.112 | 2 |
| PCF11 | PCF11 | O94913 | Pre-mRNA cleavage complex 2 protein Pcf11 | chr11 | GO:0090305 | Not Cancer Driver | No | 211 | 0.136 | 1250 | 189 | 0.151 | 0 |
| PDE12 | PDE12 | Q6L8Q7 | 2',5'-phosphodiesterase 12 | chr3 | GO:0090305 | Not Cancer Driver | No | 59 | 0.097 | 129 | 8 | 0.062 | 0 |
| PELO | PELO | Q9BRX2 | Protein pelota homolog | chr5 | GO:0090305 | Not Cancer Driver | No | 38 | 0.099 | 67 | 10 | 0.149 | 0 |
| PGBD5 | PGBD5 | Q8N414 | PiggyBac transposable element-derived protein 5 | chr1 | GO:0090305 | Not Cancer Driver | No | 73 | 0.139 | 126 | 1 | 0.008 | 0 |
| PLD3_ENST00000409735 | PLD3 | Q8IV08 | 5'-3' exonuclease PLD3 | chr19 | GO:0090305 | Not Cancer Driver | No | 70 | 0.143 | 62 | 7 | 0.113 | 0 |
| PLD4_ENST00000392593 | PLD4 | Q96BZ4 | 5'-3' exonuclease PLD4 | chr14 | GO:0090305 | Not Cancer Driver | No | 46 | 0.091 | 76 | 10 | 0.132 | 0 |
| PLSCR1 | PLSCR1 | O15162 | Phospholipid scramblase 1 | chr3 | GO:0090305 | Not Cancer Driver | No | 43 | 0.135 | 92 | 13 | 0.141 | 0 |
| PMS2 | PMS2 | P54278 | Mismatch repair endonuclease PMS2 | chr7 | GO:0090305 | Census, Compendium | Yes | 117 | 0.136 | 331 | 44 | 0.133 | 9 |
| PNKP | PNKP | Q96T60 | Bifunctional polynucleotide phosphatase/kinase | chr19 | GO:0090305 | Not Cancer Driver | No | 53 | 0.102 | 177 | 23 | 0.13 | 4 |
| PNLDC1_ENST00000610273 | PNLDC1 | Q8NA58 | Poly(A)-specific ribonuclease PNLDC1 | chr6 | GO:0090305 | Not Cancer Driver | No | 105 | 0.202 | 6 | 0 | 0.0 | 1 |
| PNPT1 | PNPT1 | Q8TCS8 | Polyribonucleotide nucleotidyltransferase 1, mitochondrial | chr2 | GO:0090305 | Not Cancer Driver | No | 86 | 0.11 | 115 | 10 | 0.087 | 2 |
| PNRC2_ENST00000374468 | PNRC2 | Q9NPJ4 | Proline-rich nuclear receptor coactivator 2 | chr1 | GO:0090305 | Not Cancer Driver | No | 1 | 0.007 | 122 | 1 | 0.008 | 0 |
| POLB | POLB | P06746 | DNA polymerase beta | chr8 | GO:0090305 | Not Cancer Driver | No | 43 | 0.128 | 87 | 11 | 0.126 | 0 |
| POLD1_ENST00000440232 | POLD1 | P28340 | DNA polymerase delta catalytic subunit | chr19 | GO:0090305 | Census, Compendium | Yes | 179 | 0.162 | 214 | 31 | 0.145 | 2 |
| POLE | POLE | Q07864 | DNA polymerase epsilon catalytic subunit A | chr12 | GO:0090305 | Census, Compendium | Yes | 409 | 0.179 | 239 | 44 | 0.184 | 3 |
| POLG_ENST00000442287 | POLG | P54098 | DNA polymerase subunit gamma-1 | chr15 | GO:0090305 | Census | Yes | 139 | 0.112 | 421 | 42 | 0.1 | 73 |
| POLR2I | POLR2I | P36954 | DNA-directed RNA polymerase II subunit RPB9 | chr19 | GO:0090305 | Not Cancer Driver | No | 21 | 0.168 | 22 | 5 | 0.227 | 0 |
| POLR3K | POLR3K | Q9Y2Y1 | DNA-directed RNA polymerase III subunit RPC10 | chr16 | GO:0090305 | Not Cancer Driver | No | 10 | 0.093 | 0 | 0 | 0.0 | 1 |
| PXDNL | PXDNL | A1KZ92 | Probable oxidoreductase PXDNL | chr8 | GO:0090305 | Not Cancer Driver | No | 554 | 0.379 | 397 | 171 | 0.431 | 0 |
| RAD1 | RAD1 | O60671 | Cell cycle checkpoint protein RAD1 | chr5 | GO:0090305 | Not Cancer Driver | No | 29 | 0.103 | 4 | 1 | 0.25 | 0 |
| RAD50 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0090305 | Not Cancer Driver | No | 157 | 0.12 | 730 | 84 | 0.115 | 0 |
| RAD9A | RAD9A | Q99638 | Cell cycle checkpoint control protein RAD9A | chr11 | GO:0090305 | Not Cancer Driver | No | 34 | 0.087 | 135 | 7 | 0.052 | 0 |
| RAG1 | RAG1 | P15918 | V(D)J recombination-activating protein 1 | chr11 | GO:0090305 | Not Cancer Driver | No | 204 | 0.196 | 208 | 43 | 0.207 | 36 |
| RBBP8_ENST00000327155 | RBBP8 | Q99708 | DNA endonuclease RBBP8 | chr18 | GO:0090305 | Not Cancer Driver | No | 99 | 0.11 | 750 | 76 | 0.101 | 1 |
| RCL1 | RCL1 | Q9Y2P8 | RNA 3'-terminal phosphate cyclase-like protein | chr9 | GO:0090305 | Not Cancer Driver | No | 40 | 0.107 | 12 | 0 | 0.0 | 0 |
| REXO1 | REXO1 | Q8N1G1 | RNA exonuclease 1 homolog | chr19 | GO:0090305 | Not Cancer Driver | No | 118 | 0.097 | 829 | 82 | 0.099 | 0 |
| REXO2 | REXO2 | Q9Y3B8 | Oligoribonuclease, mitochondrial | chr11 | GO:0090305 | Not Cancer Driver | No | 19 | 0.08 | 43 | 4 | 0.093 | 0 |
| REXO4 | REXO4 | Q9GZR2 | RNA exonuclease 4 | chr9 | GO:0090305 | Not Cancer Driver | No | 34 | 0.081 | 298 | 26 | 0.087 | 0 |
| REXO5 | REXO5 | Q96IC2 | RNA exonuclease 5 | chr16 | GO:0090305 | Not Cancer Driver | No | 89 | 0.115 | 101 | 12 | 0.119 | 0 |
| RNASE11_ENST00000620912 | RNASE11 | Q8TAA1 | Probable ribonuclease 11 | chr14 | GO:0090305 | Not Cancer Driver | No | 42 | 0.211 | 29 | 7 | 0.241 | 0 |
| RNASE4_ENST00000555597 | RNASE4 | P34096 | Ribonuclease 4 | chr14 | GO:0090305 | Not Cancer Driver | No | 24 | 0.163 | 9 | 2 | 0.222 | 0 |
| RPP40 | RPP40 | O75818 | Ribonuclease P protein subunit p40 | chr6 | GO:0090305 | Not Cancer Driver | No | 51 | 0.14 | 5 | 0 | 0.0 | 0 |
| RPS21 | RPS21 | P63220 | 40S ribosomal protein S21 | chr20 | GO:0090305 | Not Cancer Driver | No | 8 | 0.096 | 0 | 0 | 0.0 | 0 |
| RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:0090305 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
| SETMAR | SETMAR | Q53H47 | Histone-lysine N-methyltransferase SETMAR | chr3 | GO:0090305 | Not Cancer Driver | No | 62 | 0.091 | 154 | 12 | 0.078 | 0 |
| SLX1B | SLX1B | Q9BQ83 | Structure-specific endonuclease subunit SLX1 | chr16 | GO:0090305 | Not Cancer Driver | No | 3 | 0.011 | 80 | 1 | 0.013 | 0 |
| TATDN1 | TATDN1 | Q6P1N9 | Deoxyribonuclease TATDN1 | chr8 | GO:0090305 | Not Cancer Driver | No | 25 | 0.084 | 0 | 0 | 0.0 | 0 |
| TATDN2 | TATDN2 | Q93075 | Putative deoxyribonuclease TATDN2 | chr3 | GO:0090305 | Not Cancer Driver | No | 75 | 0.099 | 472 | 45 | 0.095 | 0 |
| TATDN3_ENST00000366974 | TATDN3 | Q17R31 | Putative deoxyribonuclease TATDN3 | chr1 | GO:0090305 | Not Cancer Driver | No | 37 | 0.135 | 35 | 1 | 0.029 | 0 |
| TBL3 | TBL3 | Q12788 | Transducin beta-like protein 3 | chr16 | GO:0090305 | Not Cancer Driver | No | 82 | 0.101 | 48 | 8 | 0.167 | 0 |
| TDP1_ENST00000393454 | TDP1 | Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | chr14 | GO:0090305 | Not Cancer Driver | No | 81 | 0.133 | 179 | 25 | 0.14 | 1 |
| TDP2 | TDP2 | O95551 | Tyrosyl-DNA phosphodiesterase 2 | chr6 | GO:0090305 | Not Cancer Driver | No | 55 | 0.152 | 80 | 10 | 0.125 | 0 |
| TOE1 | TOE1 | Q96GM8 | Target of EGR1 protein 1 | chr1 | GO:0090305 | Not Cancer Driver | No | 44 | 0.086 | 210 | 22 | 0.105 | 10 |
| TREX1_ENST00000625293 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0090305 | Not Cancer Driver | No | 26 | 0.083 | 98 | 10 | 0.102 | 18 |
| TREX2_ENST00000370231 | TREX2 | Q9BQ50 | Three prime repair exonuclease 2 | chrX | GO:0090305 | Not Cancer Driver | No | 33 | 0.14 | 23 | 6 | 0.261 | 0 |
| TRIR | TRIR | Q9BQ61 | Telomerase RNA component interacting RNase | chr19 | GO:0090305 | Not Cancer Driver | No | 17 | 0.097 | 176 | 17 | 0.097 | 0 |
| TSEN15 | TSEN15 | Q8WW01 | tRNA-splicing endonuclease subunit Sen15 | chr1 | GO:0090305 | Not Cancer Driver | No | 27 | 0.158 | 48 | 6 | 0.125 | 3 |
| TSN | TSN | Q15631 | Translin | chr2 | GO:0090305 | Not Cancer Driver | No | 30 | 0.132 | 0 | 0 | 0.0 | 0 |
| TUT1_ENST00000476907 | TUT1 | Q9H6E5 | Speckle targeted PIP5K1A-regulated poly(A) polymerase | chr11 | GO:0090305 | Not Cancer Driver | No | 97 | 0.111 | 410 | 50 | 0.122 | 0 |
| USB1 | USB1 | Q9BQ65 | U6 snRNA phosphodiesterase 1 | chr16 | GO:0090305 | Not Cancer Driver | No | 28 | 0.106 | 76 | 5 | 0.066 | 0 |
| UTP20 | UTP20 | O75691 | Small subunit processome component 20 homolog | chr12 | GO:0090305 | Not Cancer Driver | No | 324 | 0.116 | 314 | 35 | 0.111 | 0 |
| UTP23 | UTP23 | Q9BRU9 | rRNA-processing protein UTP23 homolog | chr8 | GO:0090305 | Not Cancer Driver | No | 35 | 0.141 | 97 | 16 | 0.165 | 0 |
| WRN | WRN | Q14191 | Werner syndrome ATP-dependent helicase | chr8 | GO:0090305 | Census, Compendium | Yes | 164 | 0.115 | 373 | 41 | 0.11 | 2 |
| XPC | XPC | Q01831 | DNA repair protein complementing XP-C cells | chr3 | GO:0090305 | Census, Compendium | Yes | 88 | 0.094 | 479 | 48 | 0.1 | 2 |
| XRN1 | XRN1 | Q8IZH2 | 5'-3' exoribonuclease 1 | chr3 | GO:0090305 | Not Cancer Driver | No | 213 | 0.125 | 577 | 65 | 0.113 | 0 |
| XRN2 | XRN2 | Q9H0D6 | 5'-3' exoribonuclease 2 | chr20 | GO:0090305 | Not Cancer Driver | No | 129 | 0.136 | 427 | 63 | 0.148 | 0 |
| ZC3H12A | ZC3H12A | Q5D1E8 | Endoribonuclease ZC3H12A | chr1 | GO:0090305 | Not Cancer Driver | No | 90 | 0.15 | 396 | 44 | 0.111 | 0 |
| ZNRD1 | POLR1H | Q9P1U0 | DNA-directed RNA polymerase I subunit RPA12 | chr6 | GO:0090305 | Not Cancer Driver | No | 6 | 0.048 | 14 | 1 | 0.071 | 0 |
| ZRANB3 | ZRANB3 | Q5FWF4 | DNA annealing helicase and endonuclease ZRANB3 | chr2 | GO:0090305 | Not Cancer Driver | No | 126 | 0.117 | 261 | 31 | 0.119 | 0 |