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Total number of protein in "GO:0090090" GO term:  135

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AC006486.1 AC006486.1 M0QYV0 Protein kinase domain-containing protein (Fragment) chr19 GO:0090090 Not Cancer Driver No 23 0.138 21 1 0.048 0
AES_ENST00000327141 TLE5 Q08117 TLE family member 5 chr19 GO:0090090 Not Cancer Driver No 16 0.081 77 7 0.091 0
AMER1 AMER1 Q5JTC6 APC membrane recruitment protein 1 chrX GO:0090090 Census, Compendium Yes 234 0.206 1039 219 0.211 0
AMER2 AMER2 Q8N7J2 APC membrane recruitment protein 2 chr13 GO:0090090 Not Cancer Driver No 118 0.176 663 116 0.175 0
AMFR AMFR Q9UKV5 E3 ubiquitin-protein ligase AMFR chr16 GO:0090090 Not Cancer Driver No 73 0.114 229 30 0.131 0
ANKRD6_ENST00000339746 ANKRD6 Q9Y2G4 Ankyrin repeat domain-containing protein 6 chr6 GO:0090090 Not Cancer Driver No 91 0.125 500 61 0.122 0
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0090090 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APC2_ENST00000233607 APC2 O95996 Adenomatous polyposis coli protein 2 chr19 GO:0090090 Not Cancer Driver No 117 0.051 1725 78 0.045 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0090090 Not Cancer Driver No 25 0.079 124 6 0.048 12
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0090090 Census, Compendium Yes 120 0.139 619 88 0.142 4
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0090090 Census, Compendium Yes 114 0.135 547 77 0.141 0
BICC1 BICC1 Q9H694 Protein bicaudal C homolog 1 chr10 GO:0090090 Not Cancer Driver No 171 0.176 645 115 0.178 1
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0090090 Not Cancer Driver No 73 0.184 139 26 0.187 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0090090 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBY1_ENST00000216029 CBY1 Q9Y3M2 Protein chibby homolog 1 chr22 GO:0090090 Not Cancer Driver No 13 0.103 98 11 0.112 0
CCDC88C CCDC88C Q9P219 Protein Daple chr14 GO:0090090 Not Cancer Driver No 270 0.133 1604 225 0.14 1
CDH2 CDH2 P19022 Cadherin-2 chr18 GO:0090090 Not Cancer Driver No 238 0.263 461 130 0.282 7
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 GO:0090090 Not Cancer Driver No 328 0.127 1411 148 0.105 0
CSNK1A1L CSNK1A1L Q8N752 Casein kinase I isoform alpha-like chr13 GO:0090090 Not Cancer Driver No 75 0.223 46 7 0.152 0
CSNK1A1_ENST00000377843 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 GO:0090090 Not Cancer Driver No 44 0.131 46 3 0.065 0
CTHRC1 CTHRC1 Q96CG8 Collagen triple helix repeat-containing protein 1 chr8 GO:0090090 Not Cancer Driver No 31 0.128 62 5 0.081 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0090090 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTNNBIP1_ENST00000377258 CTNNBIP1 Q9NSA3 Beta-catenin-interacting protein 1 chr1 GO:0090090 Not Cancer Driver No 8 0.099 64 7 0.109 0
CTNND1 CTNND1 O60716 Catenin delta-1 chr11 GO:0090090 Census Yes 154 0.159 570 83 0.146 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 GO:0090090 Census, Compendium Yes 116 0.121 213 31 0.146 3
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0090090 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0090090 Not Cancer Driver No 131 0.11 681 68 0.1 0
DACT1 DACT1 Q9NYF0 Dapper homolog 1 chr14 GO:0090090 Not Cancer Driver No 163 0.195 598 127 0.212 1
DACT3 DACT3 Q96B18 Dapper homolog 3 chr19 GO:0090090 Not Cancer Driver No 17 0.027 549 12 0.022 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0090090 Census Yes 29 0.172 160 27 0.169 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0090090 Not Cancer Driver No 58 0.218 47 8 0.17 0
DKK2 DKK2 Q9UBU2 Dickkopf-related protein 2 chr4 GO:0090090 Not Cancer Driver No 108 0.417 70 22 0.314 0
DKK3_ENST00000326932 DKK3 Q9UBP4 Dickkopf-related protein 3 chr11 GO:0090090 Not Cancer Driver No 44 0.126 161 22 0.137 0
DKK4 DKK4 Q9UBT3 Dickkopf-related protein 4 chr8 GO:0090090 Not Cancer Driver No 36 0.161 43 6 0.14 0
DKKL1 DKKL1 Q9UK85 Dickkopf-like protein 1 chr19 GO:0090090 Not Cancer Driver No 44 0.182 136 31 0.228 0
DRAXIN DRAXIN Q8NBI3 Draxin chr1 GO:0090090 Not Cancer Driver No 61 0.175 249 48 0.193 0
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0090090 Not Cancer Driver No 78 0.144 501 72 0.144 0
EMD EMD P50402 Emerin chrX GO:0090090 Not Cancer Driver No 42 0.165 160 28 0.175 4
FERMT1 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0090090 Not Cancer Driver No 100 0.148 65 8 0.123 2
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0090090 Census, Compendium Yes 81 0.124 584 75 0.128 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0090090 Census, Compendium Yes 70 0.104 595 68 0.114 0
FRMD8 FRMD8 Q9BZ67 FERM domain-containing protein 8 chr11 GO:0090090 Not Cancer Driver No 50 0.108 119 12 0.101 0
FRZB FRZB Q92765 Secreted frizzled-related protein 3 chr2 GO:0090090 Not Cancer Driver No 58 0.178 31 6 0.194 1
FUZ FUZ Q9BT04 Protein fuzzy homolog chr19 GO:0090090 Not Cancer Driver No 38 0.091 43 4 0.093 0
FZD1 FZD1 Q9UP38 Frizzled-1 chr7 GO:0090090 Not Cancer Driver No 78 0.121 133 2 0.015 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0090090 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD6 FZD6 O60353 Frizzled-6 chr8 GO:0090090 Not Cancer Driver No 95 0.135 172 15 0.087 1
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 GO:0090090 Not Cancer Driver No 85 0.182 352 65 0.185 0
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 GO:0090090 Census, Compendium Yes 206 0.186 1015 184 0.181 0
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0090090 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GPC3_ENST00000370818 GPC3 P51654 Glypican-3 chrX GO:0090090 Census Yes 89 0.153 86 11 0.128 1
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0090090 Not Cancer Driver No 25 0.136 77 12 0.156 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0090090 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0090090 Not Cancer Driver No 56 0.133 146 13 0.089 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0090090 Not Cancer Driver No 47 0.098 135 10 0.074 0
HECW1 HECW1 Q76N89 E3 ubiquitin-protein ligase HECW1 chr7 GO:0090090 Not Cancer Driver No 420 0.262 748 191 0.255 0
IGFBP1 IGFBP1 P08833 Insulin-like growth factor-binding protein 1 chr7 GO:0090090 Not Cancer Driver No 47 0.181 42 7 0.167 0
IGFBP2 IGFBP2 P18065 Insulin-like growth factor-binding protein 2 chr2 GO:0090090 Not Cancer Driver No 32 0.098 171 24 0.14 0
IGFBP4 IGFBP4 P22692 Insulin-like growth factor-binding protein 4 chr17 GO:0090090 Not Cancer Driver No 24 0.093 106 17 0.16 0
IGFBP6 IGFBP6 P24592 Insulin-like growth factor-binding protein 6 chr12 GO:0090090 Not Cancer Driver No 22 0.092 166 18 0.108 0
INVS INVS Q9Y283 Inversin chr9 GO:0090090 Not Cancer Driver No 125 0.117 487 64 0.131 2
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0090090 Not Cancer Driver No 85 0.244 180 41 0.228 0
JADE1_ENST00000512960 JADE1 Q6IE81 Protein Jade-1 chr4 GO:0090090 Not Cancer Driver No 94 0.112 409 47 0.115 0
KREMEN1_ENST00000407188 KREMEN1 Q96MU8 Kremen protein 1 chr22 GO:0090090 Not Cancer Driver No 68 0.144 73 7 0.096 1
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 GO:0090090 Census, Compendium Yes 161 0.142 788 100 0.127 0
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 GO:0090090 Census, Compendium Yes 178 0.164 687 116 0.169 0
LIMD1 LIMD1 Q9UGP4 LIM domain-containing protein 1 chr3 GO:0090090 Not Cancer Driver No 58 0.086 428 36 0.084 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 GO:0090090 Not Cancer Driver No 57 0.117 4 0 0.0 0
LRP4 LRP4 O75096 Low-density lipoprotein receptor-related protein 4 chr11 GO:0090090 Not Cancer Driver No 233 0.122 265 28 0.106 11
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 GO:0090090 Not Cancer Driver No 78 0.117 508 66 0.13 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0090090 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0090090 Not Cancer Driver No 39 0.108 25 1 0.04 0
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 GO:0090090 Not Cancer Driver No 136 0.164 589 92 0.156 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0090090 Not Cancer Driver No 15 0.105 20 2 0.1 0
MESP1 MESP1 Q9BRJ9 Mesoderm posterior protein 1 chr15 GO:0090090 Not Cancer Driver No 8 0.03 247 7 0.028 0
MLLT3 MLLT3 P42568 Protein AF-9 chr9 GO:0090090 Census, Compendium Yes 69 0.121 414 58 0.14 0
NKD1 NKD1 Q969G9 Protein naked cuticle homolog 1 chr16 GO:0090090 Not Cancer Driver No 72 0.153 436 67 0.154 0
NKD2 NKD2 Q969F2 Protein naked cuticle homolog 2 chr5 GO:0090090 Not Cancer Driver No 64 0.142 451 64 0.142 0
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0090090 Not Cancer Driver No 48 0.148 181 22 0.122 55
NOG NOG Q13253 Noggin chr17 GO:0090090 Not Cancer Driver No 22 0.095 86 9 0.105 20
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0090090 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTUM NOTUM Q6P988 Palmitoleoyl-protein carboxylesterase NOTUM chr17 GO:0090090 Not Cancer Driver No 50 0.101 73 6 0.082 0
NPHP3 NPHP3 Q7Z494 Nephrocystin-3 chr3 GO:0090090 Not Cancer Driver No 129 0.097 249 26 0.104 7
NPHP4 NPHP4 O75161 Nephrocystin-4 chr1 GO:0090090 Not Cancer Driver No 176 0.123 469 54 0.115 17
OTUD5 OTUD5 Q96G74 OTU domain-containing protein 5 chrX GO:0090090 Not Cancer Driver No 55 0.096 430 39 0.091 4
PFDN5 PFDN5 Q99471 Prefoldin subunit 5 chr12 GO:0090090 Not Cancer Driver No 18 0.117 3 0 0.0 0
PRICKLE1_ENST00000640055 PRICKLE1 Q96MT3 Prickle-like protein 1 chr12 GO:0090090 Not Cancer Driver No 146 0.176 485 91 0.188 3
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0090090 Not Cancer Driver No 110 0.237 78 15 0.192 31
PTPRO PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 GO:0090090 Not Cancer Driver No 204 0.168 137 34 0.248 0
PTPRU PTPRU Q92729 Receptor-type tyrosine-protein phosphatase U chr1 GO:0090090 Not Cancer Driver No 248 0.172 325 64 0.197 0
RBMS3 RBMS3 Q6XE24 RNA-binding motif, single-stranded-interacting protein 3 chr3 GO:0090090 Not Cancer Driver No 87 0.199 278 57 0.205 0
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 GO:0090090 Not Cancer Driver No 10 0.093 18 1 0.056 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0090090 Not Cancer Driver No 203 0.215 299 71 0.237 5
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0090090 Not Cancer Driver No 62 0.134 100 13 0.13 0
SCYL2_ENST00000360820 SCYL2 Q6P3W7 SCY1-like protein 2 chr12 GO:0090090 Not Cancer Driver No 103 0.111 328 29 0.088 0
SDHAF2 SDHAF2 Q9NX18 Succinate dehydrogenase assembly factor 2, mitochondrial chr11 GO:0090090 Census Yes 29 0.175 22 5 0.227 1
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0090090 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0090090 Not Cancer Driver No 47 0.159 1 0 0.0 0
SFRP4 SFRP4 Q6FHJ7 Secreted frizzled-related protein 4 chr7 GO:0090090 Census Yes 81 0.234 68 22 0.324 0
SFRP5 SFRP5 Q5T4F7 Secreted frizzled-related protein 5 chr10 GO:0090090 Not Cancer Driver No 26 0.082 7 3 0.429 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0090090 Not Cancer Driver No 56 0.121 139 14 0.101 81
SHISA3 SHISA3 A0PJX4 Protein shisa-3 homolog chr4 GO:0090090 Not Cancer Driver No 37 0.155 75 8 0.107 0
SHISA6_ENST00000409168 SHISA6 Q6ZSJ9 Protein shisa-6 chr17 GO:0090090 Not Cancer Driver No 29 0.058 330 22 0.067 0
SIAH2 SIAH2 O43255 E3 ubiquitin-protein ligase SIAH2 chr3 GO:0090090 Not Cancer Driver No 48 0.148 68 3 0.044 0
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0090090 Not Cancer Driver No 19 0.053 318 16 0.05 4
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0090090 Not Cancer Driver No 52 0.194 52 9 0.173 0
SOST SOST Q9BQB4 Sclerostin chr17 GO:0090090 Not Cancer Driver No 30 0.141 90 12 0.133 3
SOSTDC1 SOSTDC1 Q6X4U4 Sclerostin domain-containing protein 1 chr7 GO:0090090 Not Cancer Driver No 22 0.107 72 3 0.042 0
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0090090 Not Cancer Driver No 66 0.142 421 62 0.147 14
SOX13 SOX13 Q9UN79 Transcription factor SOX-13 chr1 GO:0090090 Not Cancer Driver No 85 0.137 564 77 0.137 0
SOX17 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 GO:0090090 Compendium Yes 81 0.196 378 59 0.156 2
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 GO:0090090 Census Yes 39 0.123 312 39 0.125 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0090090 Compendium Yes 86 0.169 495 82 0.166 18
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0090090 Census, Compendium Yes 75 0.173 135 14 0.104 9
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:0090090 Not Cancer Driver No 70 0.143 241 32 0.133 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0090090 Not Cancer Driver No 70 0.144 231 30 0.13 0
TBX18 TBX18 O95935 T-box transcription factor TBX18 chr6 GO:0090090 Not Cancer Driver No 156 0.257 356 94 0.264 2
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0090090 Census, Compendium Yes 122 0.197 516 93 0.18 0
TLE1 TLE1 Q04724 Transducin-like enhancer protein 1 chr9 GO:0090090 Not Cancer Driver No 111 0.144 381 53 0.139 0
TLE2_ENST00000262953 TLE2 Q04725 Transducin-like enhancer protein 2 chr19 GO:0090090 Not Cancer Driver No 78 0.105 283 29 0.102 0
TLE3 TLE3 Q04726 Transducin-like enhancer protein 3 chr15 GO:0090090 Not Cancer Driver No 87 0.113 381 50 0.131 0
TLE4_ENST00000376552 TLE4 Q04727 Transducin-like enhancer protein 4 chr9 GO:0090090 Not Cancer Driver No 172 0.223 381 92 0.241 0
TLE6 TLE6 Q9H808 Transducin-like enhancer protein 6 chr19 GO:0090090 Not Cancer Driver No 89 0.156 227 31 0.137 1
TLE7 TLE7 A0A1W2PR48 Transducin-like enhancer protein 7 chr16 GO:0090090 Not Cancer Driver No 1 0.002 151 0 0.0 0
TMEM131L_ENST00000409663 TMEM131L A2VDJ0 Transmembrane protein 131-like chr4 GO:0090090 Not Cancer Driver No 188 0.117 448 47 0.105 0
TMEM170B TMEM170B Q5T4T1 Transmembrane protein 170B chr6 GO:0090090 Not Cancer Driver No 17 0.129 0 0 0.0 0
TMEM64 TMEM64 Q6YI46 Transmembrane protein 64 chr8 GO:0090090 Not Cancer Driver No 33 0.087 32 0 0.0 0
TMEM88 TMEM88 Q6PEY1 Transmembrane protein 88 chr17 GO:0090090 Not Cancer Driver No 21 0.132 18 1 0.056 0
TNN TNN Q9UQP3 Tenascin-N chr1 GO:0090090 Not Cancer Driver No 426 0.328 637 231 0.363 0
TPBG_ENST00000543496 TPBG Q13641 Trophoblast glycoprotein chr6 GO:0090090 Not Cancer Driver No 58 0.138 13 1 0.077 0
UBAC2 UBAC2 Q8NBM4 Ubiquitin-associated domain-containing protein 2 chr13 GO:0090090 Not Cancer Driver No 33 0.096 57 9 0.158 0
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0090090 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0090090 Not Cancer Driver No 66 0.174 0 0 0.0 2
WWTR1_ENST00000360632 WWTR1 Q9GZV5 WW domain-containing transcription regulator protein 1 chr3 GO:0090090 Census Yes 41 0.102 387 41 0.106 0
ZNRF3 ZNRF3 Q9ULT6 E3 ubiquitin-protein ligase ZNRF3 chr22 GO:0090090 Census, Compendium Yes 94 0.1 510 51 0.1 0