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Total number of protein in "GO:0072686" GO term:  112

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AAAS AAAS Q9NRG9 Aladin chr12 GO:0072686 Not Cancer Driver No 58 0.106 116 12 0.103 3
AGBL5 AGBL5 Q8NDL9 Cytosolic carboxypeptidase-like protein 5 chr2 GO:0072686 Not Cancer Driver No 127 0.143 487 74 0.152 2
ATAT1_ENST00000376485 ATAT1 Q5SQI0 Alpha-tubulin N-acetyltransferase 1 chr6 GO:0072686 Not Cancer Driver No 31 0.074 271 20 0.074 0
C7orf43 TRAPPC14 Q8WVR3 Trafficking protein particle complex subunit 14 chr7 GO:0072686 Not Cancer Driver No 45 0.078 226 17 0.075 0
CAPG_ENST00000409724 CAPG P40121 Macrophage-capping protein chr2 GO:0072686 Not Cancer Driver No 45 0.129 95 7 0.074 0
CCDC117 CCDC117 Q8IWD4 Coiled-coil domain-containing protein 117 chr22 GO:0072686 Not Cancer Driver No 27 0.097 255 22 0.086 0
CCSAP CCSAP Q6IQ19 Centriole, cilia and spindle-associated protein chr1 GO:0072686 Not Cancer Driver No 22 0.081 241 19 0.079 0
CDC14A_ENST00000336454 CDC14A Q9UNH5 Dual specificity protein phosphatase CDC14A chr1 GO:0072686 Not Cancer Driver No 91 0.153 246 43 0.175 3
CDC14B CDC14B O60729 Dual specificity protein phosphatase CDC14B chr9 GO:0072686 Not Cancer Driver No 61 0.122 138 15 0.109 0
CDC16_ENST00000356221 CDC16 Q13042 Cell division cycle protein 16 homolog chr13 GO:0072686 Not Cancer Driver No 68 0.11 54 7 0.13 0
CDC27_ENST00000066544 CDC27 P30260 Cell division cycle protein 27 homolog chr17 GO:0072686 Not Cancer Driver No 179 0.217 289 75 0.26 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0072686 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0072686 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDC7 CDC7 O00311 Cell division cycle 7-related protein kinase chr1 GO:0072686 Not Cancer Driver No 72 0.125 185 24 0.13 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0072686 Not Cancer Driver No 40 0.135 1 0 0.0 0
CEP170 CEP170 Q5SW79 Centrosomal protein of 170 kDa chr1 GO:0072686 Not Cancer Driver No 264 0.167 1429 246 0.172 0
CKAP2L CKAP2L Q8IYA6 Cytoskeleton-associated protein 2-like chr2 GO:0072686 Not Cancer Driver No 81 0.109 572 66 0.115 0
CLASP1_ENST00000646274 CLASP1 Q7Z460 CLIP-associating protein 1 chr2 GO:0072686 Not Cancer Driver No 163 0.106 642 70 0.109 0
CLASP2 CLASP2 O75122 CLIP-associating protein 2 chr3 GO:0072686 Not Cancer Driver No 158 0.122 676 94 0.139 0
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 GO:0072686 Census, Compendium Yes 190 0.113 71 6 0.085 1
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:0072686 Census, Compendium Yes 123 0.16 167 23 0.138 3
CXCR2 CXCR2 P25025 C-X-C chemokine receptor type 2 chr2 GO:0072686 Not Cancer Driver No 87 0.242 8 0 0.0 0
DCDC1_ENST00000597505 DCDC1 M0R2J8 Doublecortin domain-containing protein 1 chr11 GO:0072686 Not Cancer Driver No 395 0.222 566 107 0.189 0
DCDC2 DCDC2 Q9UHG0 Doublecortin domain-containing protein 2 chr6 GO:0072686 Not Cancer Driver No 72 0.151 264 41 0.155 2
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 GO:0072686 Census Yes 172 0.135 817 111 0.136 11
DIAPH1 DIAPH1 O60610 Protein diaphanous homolog 1 chr5 GO:0072686 Not Cancer Driver No 118 0.093 692 57 0.082 1
DYNLL1_ENST00000242577 DYNLL1 P63167 Dynein light chain 1, cytoplasmic chr12 GO:0072686 Not Cancer Driver No 9 0.101 0 0 0.0 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0072686 Not Cancer Driver No 104 0.114 284 33 0.116 0
EFHC1 EFHC1 Q5JVL4 EF-hand domain-containing protein 1 chr6 GO:0072686 Not Cancer Driver No 79 0.123 78 15 0.192 17
EFHC2 EFHC2 Q5JST6 EF-hand domain-containing family member C2 chrX GO:0072686 Not Cancer Driver No 113 0.151 50 10 0.2 0
EML1_ENST00000262233 EML1 O00423 Echinoderm microtubule-associated protein-like 1 chr14 GO:0072686 Not Cancer Driver No 146 0.179 205 31 0.151 2
EML2_ENST00000245925 EML2 O95834 Echinoderm microtubule-associated protein-like 2 chr19 GO:0072686 Not Cancer Driver No 97 0.149 20 3 0.15 0
EML3_ENST00000394773 EML3 Q32P44 Echinoderm microtubule-associated protein-like 3 chr11 GO:0072686 Not Cancer Driver No 102 0.114 321 29 0.09 0
EML4 EML4 Q9HC35 Echinoderm microtubule-associated protein-like 4 chr2 GO:0072686 Census, Compendium Yes 105 0.107 385 41 0.106 0
EPB41_ENST00000373798 EPB41 P11171 Protein 4.1 chr1 GO:0072686 Not Cancer Driver No 101 0.117 557 69 0.124 0
ESPL1 ESPL1 Q14674 Separin chr12 GO:0072686 Not Cancer Driver No 211 0.1 380 39 0.103 0
FAM161A_ENST00000405894 FAM161A Q3B820 Protein FAM161A chr2 GO:0072686 Not Cancer Driver No 102 0.155 510 83 0.163 0
FAM83D FAM83D Q9H4H8 Protein FAM83D chr20 GO:0072686 Not Cancer Driver No 70 0.12 273 29 0.106 0
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0072686 Census, Compendium Yes 59 0.102 157 19 0.121 5
GEM GEM P55040 GTP-binding protein GEM chr8 GO:0072686 Not Cancer Driver No 64 0.216 96 22 0.229 0
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 GO:0072686 Not Cancer Driver No 115 0.115 854 96 0.112 0
HAUS3 HAUS3 Q68CZ6 HAUS augmin-like complex subunit 3 chr4 GO:0072686 Not Cancer Driver No 61 0.101 55 7 0.127 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0072686 Not Cancer Driver No 65 0.152 61 8 0.131 0
HECW2_ENST00000644256 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 GO:0072686 Not Cancer Driver No 348 0.221 845 195 0.231 4
HEPACAM2_ENST00000394468 HEPACAM2 A8MVW5 HEPACAM family member 2 chr7 GO:0072686 Not Cancer Driver No 115 0.249 50 14 0.28 0
HNF4G_ENST00000354370 HNF4G Q14541 Hepatocyte nuclear factor 4-gamma chr8 GO:0072686 Not Cancer Driver No 122 0.299 96 29 0.302 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0072686 Not Cancer Driver No 77 0.093 504 45 0.089 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX GO:0072686 Not Cancer Driver No 6 0.014 301 6 0.02 22
IL17RB IL17RB Q9NRM6 Interleukin-17 receptor B chr3 GO:0072686 Not Cancer Driver No 50 0.1 30 3 0.1 0
IQCB1 IQCB1 Q15051 IQ calmodulin-binding motif-containing protein 1 chr3 GO:0072686 Not Cancer Driver No 72 0.12 88 8 0.091 0
KATNBL1 KATNBL1 Q9H079 KATNB1-like protein 1 chr15 GO:0072686 Not Cancer Driver No 36 0.118 125 21 0.168 0
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 GO:0072686 Not Cancer Driver No 61 0.153 277 50 0.181 0
KIF11 KIF11 P52732 Kinesin-like protein KIF11 chr10 GO:0072686 Not Cancer Driver No 90 0.085 389 26 0.067 4
KIF22 KIF22 Q14807 Kinesin-like protein KIF22 chr16 GO:0072686 Not Cancer Driver No 79 0.119 322 35 0.109 4
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 GO:0072686 Not Cancer Driver No 102 0.106 559 62 0.111 0
KIF2B KIF2B Q8N4N8 Kinesin-like protein KIF2B chr17 GO:0072686 Not Cancer Driver No 314 0.467 189 116 0.614 0
KIFC1 KIFC1 Q9BW19 Kinesin-like protein KIFC1 chr6 GO:0072686 Compendium Yes 99 0.147 450 67 0.149 0
KIFC2 KIFC2 Q96AC6 Kinesin-like protein KIFC2 chr8 GO:0072686 Not Cancer Driver No 84 0.1 605 55 0.091 0
KLHL22 KLHL22 Q53GT1 Kelch-like protein 22 chr22 GO:0072686 Not Cancer Driver No 90 0.142 50 8 0.16 0
KNSTRN KNSTRN Q9Y448 Small kinetochore-associated protein chr15 GO:0072686 Census Yes 75 0.237 246 67 0.272 0
LIMK2_ENST00000331728 LIMK2 P53671 LIM domain kinase 2 chr22 GO:0072686 Not Cancer Driver No 93 0.146 146 29 0.199 0
LSM14A_ENST00000433627 LSM14A Q8ND56 Protein LSM14 homolog A chr19 GO:0072686 Census Yes 67 0.145 408 63 0.154 0
MAD1L1_ENST00000399654 MAD1L1 Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 chr7 GO:0072686 Not Cancer Driver No 117 0.163 526 77 0.146 0
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 GO:0072686 Not Cancer Driver No 26 0.127 12 1 0.083 0
MAK_ENST00000474039 MAK P20794 Serine/threonine-protein kinase MAK chr6 GO:0072686 Not Cancer Driver No 80 0.128 323 51 0.158 5
MAP4 MAP4 P27816 Microtubule-associated protein 4 chr3 GO:0072686 Not Cancer Driver No 116 0.101 1136 114 0.1 0
MAP9 MAP9 Q49MG5 Microtubule-associated protein 9 chr4 GO:0072686 Not Cancer Driver No 118 0.182 622 116 0.186 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0072686 Census, Compendium Yes 62 0.172 2 0 0.0 7
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 GO:0072686 Census, Compendium Yes 352 0.144 2347 340 0.145 0
NEIL2 NEIL2 Q969S2 Endonuclease 8-like 2 chr8 GO:0072686 Not Cancer Driver No 31 0.093 145 14 0.097 0
NEXMIF_ENST00000616200 NEXMIF Q5QGS0 Neurite extension and migration factor chrX GO:0072686 Not Cancer Driver No 404 0.266 1054 292 0.277 0
NGRN NGRN Q9NPE2 Neugrin chr15 GO:0072686 Not Cancer Driver No 26 0.089 215 21 0.098 0
NIN NIN Q8N4C6 Ninein chr14 GO:0072686 Census, Compendium Yes 239 0.114 1392 164 0.118 2
NUDC NUDC Q9Y266 Nuclear migration protein nudC chr1 GO:0072686 Not Cancer Driver No 36 0.109 235 29 0.123 0
NUDCD2 NUDCD2 Q8WVJ2 NudC domain-containing protein 2 chr5 GO:0072686 Not Cancer Driver No 12 0.076 39 6 0.154 0
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 GO:0072686 Census, Compendium Yes 234 0.111 1864 203 0.109 0
NUP62 NUP62 P37198 Nuclear pore glycoprotein p62 chr19 GO:0072686 Not Cancer Driver No 76 0.146 377 56 0.149 1
NUSAP1 NUSAP1 Q9BXS6 Nucleolar and spindle-associated protein 1 chr15 GO:0072686 Not Cancer Driver No 49 0.111 415 42 0.101 0
ODAM ODAM A1E959 Odontogenic ameloblast-associated protein chr4 GO:0072686 Not Cancer Driver No 51 0.183 140 18 0.129 0
PHLPP2 PHLPP2 Q6ZVD8 PH domain leucine-rich repeat-containing protein phosphatase 2 chr16 GO:0072686 Not Cancer Driver No 157 0.119 309 37 0.12 0
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0072686 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKHD1 PKHD1 P08F94 Fibrocystin chr6 GO:0072686 Not Cancer Driver No 778 0.191 413 81 0.196 93
PKP4 PKP4 Q99569 Plakophilin-4 chr2 GO:0072686 Not Cancer Driver No 172 0.144 756 119 0.157 0
POLDIP2 POLDIP2 Q9Y2S7 Polymerase delta-interacting protein 2 chr17 GO:0072686 Not Cancer Driver No 36 0.098 94 13 0.138 0
PYCR3_ENST00000495276 PYCR3 Q53H96 Pyrroline-5-carboxylate reductase 3 chr8 GO:0072686 Not Cancer Driver No 21 0.077 11 0 0.0 0
RACGAP1_ENST00000454520 RACGAP1 Q9H0H5 Rac GTPase-activating protein 1 chr12 GO:0072686 Not Cancer Driver No 74 0.117 255 27 0.106 0
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0072686 Not Cancer Driver No 65 0.111 159 17 0.107 0
RMDN2_ENST00000406384 RMDN2 Q96LZ7 Regulator of microtubule dynamics protein 2 chr2 GO:0072686 Not Cancer Driver No 28 0.068 81 5 0.062 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0072686 Not Cancer Driver No 22 0.091 48 4 0.083 0
RTRAF RTRAF Q9Y224 RNA transcription, translation and transport factor protein chr14 GO:0072686 Not Cancer Driver No 24 0.098 35 1 0.029 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0072686 Not Cancer Driver No 56 0.144 85 17 0.2 0
SKA1_ENST00000398452 SKA1 Q96BD8 Spindle and kinetochore-associated protein 1 chr18 GO:0072686 Not Cancer Driver No 23 0.09 74 7 0.095 0
SKA3 SKA3 Q8IX90 Spindle and kinetochore-associated protein 3 chr13 GO:0072686 Not Cancer Driver No 56 0.136 230 32 0.139 0
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0072686 Not Cancer Driver No 92 0.144 46 8 0.174 9
SPAG5 SPAG5 Q96R06 Sperm-associated antigen 5 chr17 GO:0072686 Not Cancer Driver No 136 0.114 636 83 0.131 0
SPOUT1 SPOUT1 Q5T280 Putative methyltransferase C9orf114 chr9 GO:0072686 Not Cancer Driver No 35 0.093 166 18 0.108 0
TACC3 TACC3 Q9Y6A5 Transforming acidic coiled-coil-containing protein 3 chr4 GO:0072686 Not Cancer Driver No 98 0.117 707 81 0.115 0
TAF1D TAF1D Q9H5J8 TATA box-binding protein-associated factor RNA polymerase I subunit D chr11 GO:0072686 Not Cancer Driver No 33 0.119 180 23 0.128 0
TBCK_ENST00000432496 TBCK Q8TEA7 TBC domain-containing protein kinase-like protein chr4 GO:0072686 Not Cancer Driver No 115 0.129 88 9 0.102 2
TBL1X TBL1X O60907 F-box-like/WD repeat-containing protein TBL1X chrX GO:0072686 Not Cancer Driver No 85 0.147 181 35 0.193 0
TBL1XR1 TBL1XR1 Q9BZK7 F-box-like/WD repeat-containing protein TBL1XR1 chr3 GO:0072686 Census, Compendium Yes 82 0.16 136 19 0.14 4
TFDP2 TFDP2 Q14188 Transcription factor Dp-2 chr3 GO:0072686 Not Cancer Driver No 62 0.139 248 33 0.133 0
TMEM9_ENST00000485839 TMEM9 Q9P0T7 Proton-transporting V-type ATPase complex assembly regulator TMEM9 chr1 GO:0072686 Not Cancer Driver No 22 0.12 23 3 0.13 0
TOGARAM1_ENST00000361577 TOGARAM1 Q9Y4F4 TOG array regulator of axonemal microtubules protein 1 chr14 GO:0072686 Not Cancer Driver No 230 0.134 703 101 0.144 3
TOGARAM2 TOGARAM2 Q6ZUX3 TOG array regulator of axonemal microtubules protein 2 chr2 GO:0072686 Not Cancer Driver No 177 0.174 476 96 0.202 0
TPPP TPPP O94811 Tubulin polymerization-promoting protein chr5 GO:0072686 Not Cancer Driver No 33 0.151 149 21 0.141 0
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0072686 Census Yes 311 0.132 1990 266 0.134 0
TPX2 TPX2 Q9ULW0 Targeting protein for Xklp2 chr20 GO:0072686 Not Cancer Driver No 92 0.123 695 86 0.124 0
TRAT1 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 GO:0072686 Not Cancer Driver No 86 0.462 129 67 0.519 0
WAPL_ENST00000618527 WAPL Q7Z5K2 Wings apart-like protein homolog chr10 GO:0072686 Not Cancer Driver No 140 0.118 621 68 0.11 0
WDR62_ENST00000270301 WDR62 O43379 WD repeat-containing protein 62 chr19 GO:0072686 Not Cancer Driver No 181 0.119 792 100 0.126 5
WRAP73 WRAP73 Q9P2S5 WD repeat-containing protein WRAP73 chr1 GO:0072686 Not Cancer Driver No 50 0.109 5 0 0.0 0