Total number of protein in "GO:0071560" GO term: 58
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0071560 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
ACVRL1 | ACVRL1 | P37023 | Serine/threonine-protein kinase receptor R3 | chr12 | GO:0071560 | Not Cancer Driver | No | 93 | 0.185 | 60 | 11 | 0.183 | 82 |
ANKRD1 | ANKRD1 | Q15327 | Ankyrin repeat domain-containing protein 1 | chr10 | GO:0071560 | Not Cancer Driver | No | 52 | 0.163 | 83 | 13 | 0.157 | 0 |
APAF1 | APAF1 | O14727 | Apoptotic protease-activating factor 1 | chr12 | GO:0071560 | Not Cancer Driver | No | 127 | 0.102 | 17 | 1 | 0.059 | 0 |
ARG1_ENST00000368087 | ARG1 | P05089 | Arginase-1 | chr6 | GO:0071560 | Not Cancer Driver | No | 41 | 0.127 | 83 | 12 | 0.145 | 9 |
CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0071560 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
CDKN2B | CDKN2B | P42772 | Cyclin-dependent kinase 4 inhibitor B | chr9 | GO:0071560 | Not Cancer Driver | No | 15 | 0.109 | 67 | 3 | 0.045 | 0 |
CILP | CILP | O75339 | Cartilage intermediate layer protein 1 | chr15 | GO:0071560 | Not Cancer Driver | No | 206 | 0.174 | 278 | 44 | 0.158 | 0 |
CLDN1 | CLDN1 | O95832 | Claudin-1 | chr3 | GO:0071560 | Not Cancer Driver | No | 31 | 0.147 | 16 | 3 | 0.188 | 0 |
CLEC3B | CLEC3B | P05452 | Tetranectin | chr3 | GO:0071560 | Not Cancer Driver | No | 34 | 0.168 | 50 | 13 | 0.26 | 0 |
COL1A1 | COL1A1 | P02452 | Collagen alpha-1(I) chain | chr17 | GO:0071560 | Census, Compendium | Yes | 247 | 0.169 | 1212 | 214 | 0.177 | 148 |
COL4A2 | COL4A2 | P08572 | Collagen alpha-2(IV) chain | chr13 | GO:0071560 | Not Cancer Driver | No | 264 | 0.154 | 1462 | 234 | 0.16 | 2 |
CRK | CRK | P46108 | Adapter molecule crk | chr17 | GO:0071560 | Not Cancer Driver | No | 30 | 0.099 | 197 | 23 | 0.117 | 0 |
CRKL | CRKL | P46109 | Crk-like protein | chr22 | GO:0071560 | Not Cancer Driver | No | 38 | 0.125 | 160 | 25 | 0.156 | 0 |
CX3CR1_ENST00000542107 | CX3CR1 | P49238 | CX3C chemokine receptor 1 | chr3 | GO:0071560 | Not Cancer Driver | No | 80 | 0.225 | 0 | 0 | 0.0 | 0 |
DAB2 | DAB2 | P98082 | Disabled homolog 2 | chr5 | GO:0071560 | Not Cancer Driver | No | 144 | 0.187 | 680 | 125 | 0.184 | 0 |
DLX1 | DLX1 | P56177 | Homeobox protein DLX-1 | chr2 | GO:0071560 | Not Cancer Driver | No | 25 | 0.098 | 183 | 21 | 0.115 | 0 |
EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0071560 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
EPB41L5 | EPB41L5 | Q9HCM4 | Band 4.1-like protein 5 | chr2 | GO:0071560 | Not Cancer Driver | No | 97 | 0.132 | 312 | 45 | 0.144 | 0 |
FBN1 | FBN1 | P35555 | Fibrillin-1 | chr15 | GO:0071560 | Not Cancer Driver | No | 466 | 0.162 | 110 | 16 | 0.145 | 360 |
FGFR2_ENST00000358487 | FGFR2 | P21802 | Fibroblast growth factor receptor 2 | chr10 | GO:0071560 | Census, Compendium | Yes | 238 | 0.29 | 228 | 44 | 0.193 | 72 |
FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0071560 | Not Cancer Driver | No | 92 | 0.171 | 70 | 13 | 0.186 | 0 |
HDAC2 | HDAC2 | Q92769 | Histone deacetylase 2 | chr6 | GO:0071560 | Not Cancer Driver | No | 46 | 0.094 | 145 | 14 | 0.097 | 0 |
HYAL2_ENST00000357750 | HYAL2 | Q12891 | Hyaluronidase-2 | chr3 | GO:0071560 | Not Cancer Driver | No | 52 | 0.11 | 8 | 1 | 0.125 | 0 |
IGF1R | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0071560 | Not Cancer Driver | No | 183 | 0.134 | 265 | 37 | 0.14 | 6 |
LIMS1_ENST00000393310 | LIMS1 | P48059 | LIM and senescent cell antigen-like-containing domain protein 1 | chr2 | GO:0071560 | Not Cancer Driver | No | 34 | 0.105 | 0 | 0 | 0.0 | 0 |
MAPK7 | MAPK7 | Q13164 | Mitogen-activated protein kinase 7 | chr17 | GO:0071560 | Not Cancer Driver | No | 92 | 0.113 | 490 | 50 | 0.102 | 0 |
MEF2C_ENST00000504921 | MEF2C | Q06413 | Myocyte-specific enhancer factor 2C | chr5 | GO:0071560 | Not Cancer Driver | No | 92 | 0.195 | 408 | 81 | 0.199 | 0 |
NR3C1_ENST00000343796 | NR3C1 | P04150 | Glucocorticoid receptor | chr5 | GO:0071560 | Not Cancer Driver | No | 92 | 0.118 | 362 | 37 | 0.102 | 12 |
OVOL2 | OVOL2 | Q9BRP0 | Transcription factor Ovo-like 2 | chr20 | GO:0071560 | Not Cancer Driver | No | 29 | 0.105 | 139 | 8 | 0.058 | 0 |
PAK2 | PAK2 | Q13177 | Serine/threonine-protein kinase PAK 2 | chr3 | GO:0071560 | Compendium | Yes | 89 | 0.17 | 242 | 49 | 0.202 | 0 |
PDCD5 | PDCD5 | O14737 | Programmed cell death protein 5 | chr19 | GO:0071560 | Not Cancer Driver | No | 15 | 0.12 | 91 | 7 | 0.077 | 0 |
PDE2A | PDE2A | O00408 | cGMP-dependent 3',5'-cyclic phosphodiesterase | chr11 | GO:0071560 | Not Cancer Driver | No | 137 | 0.146 | 99 | 7 | 0.071 | 0 |
PDE3A | PDE3A | Q14432 | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | chr12 | GO:0071560 | Not Cancer Driver | No | 274 | 0.24 | 527 | 114 | 0.216 | 6 |
PDGFA | PDGFA | P04085 | Platelet-derived growth factor subunit A | chr7 | GO:0071560 | Not Cancer Driver | No | 31 | 0.147 | 75 | 10 | 0.133 | 0 |
PDGFD | PDGFD | Q9GZP0 | Platelet-derived growth factor D | chr11 | GO:0071560 | Not Cancer Driver | No | 85 | 0.23 | 37 | 13 | 0.351 | 0 |
PENK_ENST00000451791 | PENK | P01210 | Proenkephalin-A | chr8 | GO:0071560 | Not Cancer Driver | No | 109 | 0.408 | 142 | 62 | 0.437 | 0 |
PPM1A_ENST00000395076 | PPM1A | P35813 | Protein phosphatase 1A | chr14 | GO:0071560 | Not Cancer Driver | No | 60 | 0.157 | 134 | 24 | 0.179 | 0 |
SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0071560 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0071560 | Census, Compendium | Yes | 97 | 0.228 | 111 | 19 | 0.171 | 5 |
SMAD7 | SMAD7 | O15105 | Mothers against decapentaplegic homolog 7 | chr18 | GO:0071560 | Not Cancer Driver | No | 40 | 0.094 | 139 | 0 | 0.0 | 0 |
SOX5 | SOX5 | P35711 | Transcription factor SOX-5 | chr12 | GO:0071560 | Not Cancer Driver | No | 182 | 0.239 | 665 | 162 | 0.244 | 0 |
SOX6_ENST00000528429 | SOX6 | P35712 | Transcription factor SOX-6 | chr11 | GO:0071560 | Not Cancer Driver | No | 130 | 0.157 | 744 | 118 | 0.159 | 0 |
SOX9 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0071560 | Compendium | Yes | 86 | 0.169 | 495 | 82 | 0.166 | 18 |
STK16_ENST00000396738 | STK16 | O75716 | Serine/threonine-protein kinase 16 | chr2 | GO:0071560 | Not Cancer Driver | No | 42 | 0.138 | 48 | 3 | 0.062 | 0 |
TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0071560 | Not Cancer Driver | No | 41 | 0.105 | 41 | 4 | 0.098 | 10 |
TGFBR1_ENST00000374994 | TGFBR1 | P36897 | TGF-beta receptor type-1 | chr9 | GO:0071560 | Not Cancer Driver | No | 86 | 0.171 | 23 | 3 | 0.13 | 15 |
WNT10A | WNT10A | Q9GZT5 | Protein Wnt-10a | chr2 | GO:0071560 | Not Cancer Driver | No | 39 | 0.094 | 123 | 10 | 0.081 | 9 |
WNT2 | WNT2 | P09544 | Protein Wnt-2 | chr7 | GO:0071560 | Not Cancer Driver | No | 85 | 0.236 | 11 | 3 | 0.273 | 0 |
WNT4 | WNT4 | P56705 | Protein Wnt-4 | chr1 | GO:0071560 | Not Cancer Driver | No | 30 | 0.085 | 39 | 4 | 0.103 | 4 |
WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0071560 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
WNT7A | WNT7A | O00755 | Protein Wnt-7a | chr3 | GO:0071560 | Not Cancer Driver | No | 93 | 0.266 | 18 | 9 | 0.5 | 4 |
WWOX | WWOX | Q9NZC7 | WW domain-containing oxidoreductase | chr16 | GO:0071560 | Not Cancer Driver | No | 79 | 0.191 | 108 | 9 | 0.083 | 3 |
XCL1 | XCL1 | P47992 | Lymphotactin | chr1 | GO:0071560 | Not Cancer Driver | No | 28 | 0.246 | 35 | 11 | 0.314 | 0 |
YES1_ENST00000314574 | YES1 | P07947 | Tyrosine-protein kinase Yes | chr18 | GO:0071560 | Not Cancer Driver | No | 65 | 0.12 | 62 | 10 | 0.161 | 0 |
ZEB1_ENST00000320985 | ZEB1 | P37275 | Zinc finger E-box-binding homeobox 1 | chr10 | GO:0071560 | Census, Compendium | Yes | 246 | 0.219 | 831 | 200 | 0.241 | 8 |
ZFP36L1 | ZFP36L1 | Q07352 | mRNA decay activator protein ZFP36L1 | chr14 | GO:0071560 | Compendium | Yes | 57 | 0.169 | 212 | 30 | 0.142 | 0 |
ZFP36L2 | ZFP36L2 | P47974 | mRNA decay activator protein ZFP36L2 | chr2 | GO:0071560 | Not Cancer Driver | No | 73 | 0.148 | 324 | 45 | 0.139 | 0 |