Total number of protein in "GO:0071482" GO term: 108
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTR5 | ACTR5 | Q9H9F9 | Actin-related protein 5 | chr20 | GO:0071482 | Not Cancer Driver | No | 63 | 0.104 | 163 | 23 | 0.141 | 0 |
| AKT2 | AKT2 | P31751 | RAC-beta serine/threonine-protein kinase | chr19 | GO:0071482 | Census | Yes | 77 | 0.16 | 84 | 9 | 0.107 | 2 |
| AQP1 | AQP1 | P29972 | Aquaporin-1 | chr7 | GO:0071482 | Not Cancer Driver | No | 39 | 0.145 | 4 | 1 | 0.25 | 0 |
| ATF4_ENST00000404241 | ATF4 | P18848 | Cyclic AMP-dependent transcription factor ATF-4 | chr22 | GO:0071482 | Not Cancer Driver | No | 53 | 0.151 | 259 | 38 | 0.147 | 0 |
| ATR | ATR | Q13535 | Serine/threonine-protein kinase ATR | chr3 | GO:0071482 | Census, Compendium | Yes | 338 | 0.128 | 106 | 14 | 0.132 | 1 |
| AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | GO:0071482 | Not Cancer Driver | No | 51 | 0.148 | 63 | 8 | 0.127 | 0 |
| BAK1 | BAK1 | Q16611 | Bcl-2 homologous antagonist/killer | chr6 | GO:0071482 | Not Cancer Driver | No | 38 | 0.18 | 58 | 9 | 0.155 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0071482 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BMF_ENST00000561360 | BMF | Q96LC9 | Bcl-2-modifying factor | chr15 | GO:0071482 | Not Cancer Driver | No | 22 | 0.12 | 94 | 9 | 0.096 | 0 |
| CARD16 | CARD16 | Q5EG05 | Caspase recruitment domain-containing protein 16 | chr11 | GO:0071482 | Not Cancer Driver | No | 36 | 0.183 | 23 | 7 | 0.304 | 0 |
| CASP9 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0071482 | Census | Yes | 49 | 0.118 | 71 | 7 | 0.099 | 0 |
| CDC25A | CDC25A | P30304 | M-phase inducer phosphatase 1 | chr3 | GO:0071482 | Not Cancer Driver | No | 63 | 0.12 | 313 | 35 | 0.112 | 0 |
| CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0071482 | Census, Compendium | Yes | 48 | 0.293 | 121 | 30 | 0.248 | 0 |
| CERS1_ENST00000623882 | CERS1 | P27544 | Ceramide synthase 1 | chr19 | GO:0071482 | Not Cancer Driver | No | 29 | 0.083 | 19 | 0 | 0.0 | 1 |
| CHEK1_ENST00000428830 | CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 | chr11 | GO:0071482 | Not Cancer Driver | No | 58 | 0.122 | 86 | 16 | 0.186 | 0 |
| COPS9_ENST00000607357 | COPS9 | Q8WXC6 | COP9 signalosome complex subunit 9 | chr2 | GO:0071482 | Not Cancer Driver | No | 6 | 0.105 | 25 | 3 | 0.12 | 0 |
| CRB1 | CRB1 | P82279 | Protein crumbs homolog 1 | chr1 | GO:0071482 | Not Cancer Driver | No | 464 | 0.33 | 28 | 5 | 0.179 | 74 |
| CREBBP | CREBBP | Q92793 | CREB-binding protein | chr16 | GO:0071482 | Census, Compendium | Yes | 412 | 0.169 | 1796 | 247 | 0.138 | 33 |
| CRIP1_ENST00000409393 | CRIP1 | P50238 | Cysteine-rich protein 1 | chr14 | GO:0071482 | Not Cancer Driver | No | 6 | 0.078 | 8 | 1 | 0.125 | 0 |
| CRY1 | CRY1 | Q16526 | Cryptochrome-1 | chr12 | GO:0071482 | Not Cancer Driver | No | 76 | 0.13 | 91 | 5 | 0.055 | 0 |
| CRY2_ENST00000616080 | CRY2 | Q49AN0 | Cryptochrome-2 | chr11 | GO:0071482 | Not Cancer Driver | No | 72 | 0.121 | 100 | 12 | 0.12 | 0 |
| CUL4B | CUL4B | Q13620 | Cullin-4B | chrX | GO:0071482 | Not Cancer Driver | No | 138 | 0.151 | 207 | 38 | 0.184 | 2 |
| DDB1 | DDB1 | Q16531 | DNA damage-binding protein 1 | chr11 | GO:0071482 | Not Cancer Driver | No | 126 | 0.111 | 50 | 8 | 0.16 | 4 |
| DDB2 | DDB2 | Q92466 | DNA damage-binding protein 2 | chr11 | GO:0071482 | Census, Compendium | Yes | 45 | 0.105 | 70 | 5 | 0.071 | 2 |
| DHX36 | DHX36 | Q9H2U1 | ATP-dependent DNA/RNA helicase DHX36 | chr3 | GO:0071482 | Not Cancer Driver | No | 159 | 0.158 | 222 | 39 | 0.176 | 0 |
| EIF2AK4 | EIF2AK4 | Q9P2K8 | eIF-2-alpha kinase GCN2 | chr15 | GO:0071482 | Not Cancer Driver | No | 156 | 0.095 | 494 | 44 | 0.089 | 2 |
| EIF2S1 | EIF2S1 | P05198 | Eukaryotic translation initiation factor 2 subunit 1 | chr14 | GO:0071482 | Not Cancer Driver | No | 35 | 0.111 | 59 | 6 | 0.102 | 0 |
| EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0071482 | Census, Compendium | Yes | 334 | 0.138 | 1790 | 196 | 0.109 | 1 |
| ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0071482 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
| ERCC4 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:0071482 | Census | Yes | 120 | 0.131 | 225 | 27 | 0.12 | 15 |
| FMR1 | FMR1 | Q06787 | Synaptic functional regulator FMR1 | chrX | GO:0071482 | Not Cancer Driver | No | 124 | 0.196 | 327 | 70 | 0.214 | 3 |
| GNAT1 | GNAT1 | P11488 | Guanine nucleotide-binding protein G(t) subunit alpha-1 | chr3 | GO:0071482 | Not Cancer Driver | No | 43 | 0.123 | 39 | 6 | 0.154 | 3 |
| GNB5 | GNB5 | O14775 | Guanine nucleotide-binding protein subunit beta-5 | chr15 | GO:0071482 | Not Cancer Driver | No | 60 | 0.152 | 16 | 1 | 0.062 | 1 |
| GPR52 | GPR52 | Q9Y2T5 | G-protein coupled receptor 52 | chr1 | GO:0071482 | Not Cancer Driver | No | 48 | 0.133 | 9 | 2 | 0.222 | 0 |
| GPR88 | GPR88 | Q9GZN0 | Probable G-protein coupled receptor 88 | chr1 | GO:0071482 | Not Cancer Driver | No | 15 | 0.039 | 30 | 0 | 0.0 | 0 |
| GRK1 | GRK1 | Q15835 | Rhodopsin kinase GRK1 | chr13 | GO:0071482 | Not Cancer Driver | No | 70 | 0.124 | 32 | 2 | 0.062 | 2 |
| HIST3H2A | H2AW | Q7L7L0 | Histone H2A type 3 | chr1 | GO:0071482 | Not Cancer Driver | No | 21 | 0.162 | 61 | 10 | 0.164 | 0 |
| HYAL1_ENST00000395144 | HYAL1 | Q12794 | Hyaluronidase-1 | chr3 | GO:0071482 | Not Cancer Driver | No | 47 | 0.108 | 9 | 0 | 0.0 | 1 |
| HYAL2_ENST00000357750 | HYAL2 | Q12891 | Hyaluronidase-2 | chr3 | GO:0071482 | Not Cancer Driver | No | 52 | 0.11 | 8 | 1 | 0.125 | 0 |
| HYAL3 | HYAL3 | O43820 | Hyaluronidase-3 | chr3 | GO:0071482 | Not Cancer Driver | No | 48 | 0.115 | 10 | 0 | 0.0 | 0 |
| IMPACT | IMPACT | Q9P2X3 | Protein IMPACT | chr18 | GO:0071482 | Not Cancer Driver | No | 49 | 0.153 | 84 | 12 | 0.143 | 0 |
| INO80_ENST00000401393 | INO80 | Q9ULG1 | Chromatin-remodeling ATPase INO80 | chr15 | GO:0071482 | Compendium | Yes | 173 | 0.111 | 682 | 76 | 0.111 | 0 |
| KDM1A_ENST00000356634 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | GO:0071482 | Not Cancer Driver | No | 67 | 0.079 | 291 | 28 | 0.096 | 3 |
| MAPK13 | MAPK13 | O15264 | Mitogen-activated protein kinase 13 | chr6 | GO:0071482 | Not Cancer Driver | No | 51 | 0.14 | 50 | 15 | 0.3 | 0 |
| MC1R_ENST00000639847 | MC1R | Q01726 | Melanocyte-stimulating hormone receptor | chr16 | GO:0071482 | Not Cancer Driver | No | 39 | 0.123 | 0 | 0 | 0.0 | 5 |
| METTL3 | METTL3 | Q86U44 | N6-adenosine-methyltransferase catalytic subunit | chr14 | GO:0071482 | Not Cancer Driver | No | 74 | 0.128 | 274 | 29 | 0.106 | 0 |
| MFAP4_ENST00000299610 | MFAP4 | P55083 | Microfibril-associated glycoprotein 4 | chr17 | GO:0071482 | Not Cancer Driver | No | 35 | 0.137 | 0 | 0 | 0.0 | 0 |
| MME_ENST00000492661 | MME | P08473 | Neprilysin | chr3 | GO:0071482 | Not Cancer Driver | No | 189 | 0.252 | 40 | 17 | 0.425 | 4 |
| MMP1 | MMP1 | P03956 | Interstitial collagenase | chr11 | GO:0071482 | Not Cancer Driver | No | 83 | 0.177 | 113 | 18 | 0.159 | 0 |
| MMP2 | MMP2 | P08253 | 72 kDa type IV collagenase | chr16 | GO:0071482 | Not Cancer Driver | No | 123 | 0.186 | 29 | 6 | 0.207 | 2 |
| MMP3 | MMP3 | P08254 | Stromelysin-1 | chr11 | GO:0071482 | Not Cancer Driver | No | 99 | 0.208 | 66 | 14 | 0.212 | 0 |
| MMP9 | MMP9 | P14780 | Matrix metalloproteinase-9 | chr20 | GO:0071482 | Not Cancer Driver | No | 129 | 0.182 | 124 | 26 | 0.21 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:0071482 | Census, Compendium | Yes | 80 | 0.182 | 299 | 46 | 0.154 | 0 |
| N4BP1 | N4BP1 | O75113 | NEDD4-binding protein 1 | chr16 | GO:0071482 | Not Cancer Driver | No | 108 | 0.121 | 432 | 58 | 0.134 | 0 |
| NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | GO:0071482 | Not Cancer Driver | No | 150 | 0.114 | 711 | 79 | 0.111 | 0 |
| NFATC4_ENST00000250373 | NFATC4 | Q14934 | Nuclear factor of activated T-cells, cytoplasmic 4 | chr14 | GO:0071482 | Not Cancer Driver | No | 155 | 0.172 | 685 | 120 | 0.175 | 0 |
| NOC2L | NOC2L | Q9Y3T9 | Nucleolar complex protein 2 homolog | chr1 | GO:0071482 | Not Cancer Driver | No | 77 | 0.103 | 281 | 31 | 0.11 | 0 |
| NPM1 | NPM1 | P06748 | Nucleophosmin | chr5 | GO:0071482 | Census, Compendium | Yes | 29 | 0.099 | 249 | 22 | 0.088 | 0 |
| NSMCE3 | NSMCE3 | Q96MG7 | Non-structural maintenance of chromosomes element 3 homolog | chr15 | GO:0071482 | Not Cancer Driver | No | 33 | 0.109 | 128 | 7 | 0.055 | 2 |
| OPN1LW | OPN1LW | P04000 | Long-wave-sensitive opsin 1 | chrX | GO:0071482 | Not Cancer Driver | No | 72 | 0.198 | 9 | 0 | 0.0 | 3 |
| OPN1MW | OPN1MW | P04001 | Medium-wave-sensitive opsin 1 | chrX | GO:0071482 | Not Cancer Driver | No | 10 | 0.027 | 6 | 0 | 0.0 | 5 |
| OPN1MW2 | OPN1MW2 | P0DN77 | Medium-wave-sensitive opsin 2 | chrX | GO:0071482 | Not Cancer Driver | No | 22 | 0.06 | 6 | 0 | 0.0 | 0 |
| OPN1SW | OPN1SW | P03999 | Short-wave-sensitive opsin 1 | chr7 | GO:0071482 | Not Cancer Driver | No | 65 | 0.187 | 20 | 1 | 0.05 | 4 |
| OPN3 | OPN3 | Q9H1Y3 | Opsin-3 | chr1 | GO:0071482 | Not Cancer Driver | No | 39 | 0.097 | 6 | 1 | 0.167 | 0 |
| OPN4_ENST00000241891 | OPN4 | Q9UHM6 | Melanopsin | chr10 | GO:0071482 | Not Cancer Driver | No | 84 | 0.176 | 88 | 9 | 0.102 | 0 |
| OPN5 | OPN5 | Q6U736 | Opsin-5 | chr6 | GO:0071482 | Not Cancer Driver | No | 65 | 0.184 | 0 | 0 | 0.0 | 0 |
| PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:0071482 | Not Cancer Driver | No | 119 | 0.117 | 320 | 34 | 0.106 | 0 |
| PBK_ENST00000301905 | PBK | Q96KB5 | Lymphokine-activated killer T-cell-originated protein kinase | chr8 | GO:0071482 | Not Cancer Driver | No | 23 | 0.071 | 92 | 6 | 0.065 | 0 |
| PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | GO:0071482 | Not Cancer Driver | No | 30 | 0.115 | 22 | 3 | 0.136 | 1 |
| PIK3R1 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0071482 | Census, Compendium | Yes | 154 | 0.213 | 268 | 61 | 0.228 | 2 |
| POLD1_ENST00000440232 | POLD1 | P28340 | DNA polymerase delta catalytic subunit | chr19 | GO:0071482 | Census, Compendium | Yes | 179 | 0.162 | 214 | 31 | 0.145 | 2 |
| POLH | POLH | Q9Y253 | DNA polymerase eta | chr6 | GO:0071482 | Not Cancer Driver | No | 72 | 0.101 | 291 | 20 | 0.069 | 10 |
| POLK | POLK | Q9UBT6 | DNA polymerase kappa | chr5 | GO:0071482 | Not Cancer Driver | No | 97 | 0.111 | 293 | 36 | 0.123 | 0 |
| PPID | PPID | Q08752 | Peptidyl-prolyl cis-trans isomerase D | chr4 | GO:0071482 | Not Cancer Driver | No | 36 | 0.097 | 94 | 9 | 0.096 | 0 |
| PRKCD_ENST00000330452 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | GO:0071482 | Compendium | Yes | 79 | 0.117 | 43 | 9 | 0.209 | 0 |
| PTGS2 | PTGS2 | P35354 | Prostaglandin G/H synthase 2 | chr1 | GO:0071482 | Not Cancer Driver | No | 105 | 0.174 | 30 | 5 | 0.167 | 0 |
| PTPRK_ENST00000368215 | PTPRK | Q15262 | Receptor-type tyrosine-protein phosphatase kappa | chr6 | GO:0071482 | Census, Compendium | Yes | 292 | 0.203 | 302 | 57 | 0.189 | 0 |
| RGR | RGR | P47804 | RPE-retinal G protein-coupled receptor | chr10 | GO:0071482 | Not Cancer Driver | No | 42 | 0.144 | 6 | 3 | 0.5 | 1 |
| RGS9 | RGS9 | O75916 | Regulator of G-protein signaling 9 | chr17 | GO:0071482 | Not Cancer Driver | No | 138 | 0.205 | 240 | 65 | 0.271 | 1 |
| RHBDD1 | RHBDD1 | Q8TEB9 | Rhomboid-related protein 4 | chr2 | GO:0071482 | Not Cancer Driver | No | 38 | 0.121 | 69 | 9 | 0.13 | 0 |
| RHNO1 | RHNO1 | Q9BSD3 | RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 | chr12 | GO:0071482 | Not Cancer Driver | No | 26 | 0.109 | 193 | 21 | 0.109 | 0 |
| RHO | RHO | P08100 | Rhodopsin | chr3 | GO:0071482 | Not Cancer Driver | No | 68 | 0.195 | 18 | 3 | 0.167 | 69 |
| RP1 | RP1 | P56715 | Oxygen-regulated protein 1 | chr8 | GO:0071482 | Not Cancer Driver | No | 737 | 0.342 | 1215 | 441 | 0.363 | 6 |
| RPL26 | RPL26 | P61254 | 60S ribosomal protein L26 | chr17 | GO:0071482 | Not Cancer Driver | No | 16 | 0.11 | 114 | 13 | 0.114 | 0 |
| RRH | RRH | O14718 | Visual pigment-like receptor peropsin | chr4 | GO:0071482 | Not Cancer Driver | No | 34 | 0.101 | 15 | 0 | 0.0 | 0 |
| RUVBL2 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | GO:0071482 | Not Cancer Driver | No | 62 | 0.134 | 100 | 13 | 0.13 | 0 |
| SAG | SAG | P10523 | S-arrestin | chr2 | GO:0071482 | Not Cancer Driver | No | 70 | 0.173 | 102 | 11 | 0.108 | 0 |
| SDE2 | SDE2 | Q6IQ49 | Replication stress response regulator SDE2 | chr1 | GO:0071482 | Not Cancer Driver | No | 56 | 0.124 | 290 | 35 | 0.121 | 0 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0071482 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
| SLC24A2 | SLC24A2 | Q9UI40 | Sodium/potassium/calcium exchanger 2 | chr9 | GO:0071482 | Not Cancer Driver | No | 120 | 0.182 | 144 | 24 | 0.167 | 0 |
| SLC24A4 | SLC24A4 | Q8NFF2 | Sodium/potassium/calcium exchanger 4 | chr14 | GO:0071482 | Not Cancer Driver | No | 121 | 0.195 | 85 | 14 | 0.165 | 2 |
| SMPD1 | SMPD1 | P17405 | Sphingomyelin phosphodiesterase | chr11 | GO:0071482 | Not Cancer Driver | No | 93 | 0.147 | 51 | 4 | 0.078 | 111 |
| ST20_ENST00000562759 | ST20 | Q9HBF5 | Suppressor of tumorigenicity 20 protein | chr15 | GO:0071482 | Not Cancer Driver | No | 17 | 0.215 | 0 | 0 | 0.0 | 0 |
| STK11 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | GO:0071482 | Census, Compendium | Yes | 75 | 0.173 | 135 | 14 | 0.104 | 9 |
| TAF1_ENST00000373790 | TAF1 | P21675 | Transcription initiation factor TFIID subunit 1 | chrX | GO:0071482 | Not Cancer Driver | No | 379 | 0.202 | 1152 | 219 | 0.19 | 5 |
| TENT2_ENST00000428308 | TENT2 | Q6PIY7 | Poly(A) RNA polymerase GLD2 | chr5 | GO:0071482 | Not Cancer Driver | No | 65 | 0.134 | 75 | 15 | 0.2 | 0 |
| TIMP1 | TIMP1 | P01033 | Metalloproteinase inhibitor 1 | chrX | GO:0071482 | Not Cancer Driver | No | 25 | 0.121 | 0 | 0 | 0.0 | 0 |
| TMEM161A | TMEM161A | Q9NX61 | Transmembrane protein 161A | chr19 | GO:0071482 | Not Cancer Driver | No | 49 | 0.102 | 22 | 8 | 0.364 | 0 |
| TP53INP1 | TP53INP1 | Q96A56 | Tumor protein p53-inducible nuclear protein 1 | chr8 | GO:0071482 | Not Cancer Driver | No | 32 | 0.133 | 134 | 20 | 0.149 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0071482 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TRIAP1 | TRIAP1 | O43715 | TP53-regulated inhibitor of apoptosis 1 | chr12 | GO:0071482 | Not Cancer Driver | No | 9 | 0.118 | 20 | 1 | 0.05 | 0 |
| TRPM1_ENST00000397795 | TRPM1 | Q7Z4N2 | Transient receptor potential cation channel subfamily M member 1 | chr15 | GO:0071482 | Not Cancer Driver | No | 254 | 0.158 | 516 | 74 | 0.143 | 12 |
| USP28 | USP28 | Q96RU2 | Ubiquitin carboxyl-terminal hydrolase 28 | chr11 | GO:0071482 | Not Cancer Driver | No | 151 | 0.14 | 311 | 25 | 0.08 | 0 |
| USP47 | USP47 | Q96K76 | Ubiquitin carboxyl-terminal hydrolase 47 | chr11 | GO:0071482 | Not Cancer Driver | No | 137 | 0.1 | 425 | 39 | 0.092 | 0 |
| XPA | XPA | P23025 | DNA repair protein complementing XP-A cells | chr9 | GO:0071482 | Census | Yes | 27 | 0.099 | 121 | 13 | 0.107 | 5 |
| XPC | XPC | Q01831 | DNA repair protein complementing XP-C cells | chr3 | GO:0071482 | Census, Compendium | Yes | 88 | 0.094 | 479 | 48 | 0.1 | 2 |
| YY1 | YY1 | P25490 | Transcriptional repressor protein YY1 | chr14 | GO:0071482 | Not Cancer Driver | No | 37 | 0.089 | 336 | 26 | 0.077 | 2 |
| ZBTB1 | ZBTB1 | Q9Y2K1 | Zinc finger and BTB domain-containing protein 1 | chr14 | GO:0071482 | Not Cancer Driver | No | 70 | 0.098 | 271 | 27 | 0.1 | 0 |