Total number of protein in "GO:0071383" GO term: 76
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACE | ACE | P12821 | Angiotensin-converting enzyme | chr17 | GO:0071383 | Not Cancer Driver | No | 201 | 0.154 | 86 | 8 | 0.093 | 0 |
| ACOD1 | ACOD1 | A6NK06 | Cis-aconitate decarboxylase | chr13 | GO:0071383 | Not Cancer Driver | No | 5 | 0.01 | 36 | 0 | 0.0 | 0 |
| ACVR1_ENST00000434821 | ACVR1 | Q04771 | Activin receptor type-1 | chr2 | GO:0071383 | Census, Compendium | Yes | 78 | 0.153 | 21 | 8 | 0.381 | 8 |
| ADTRP_ENST00000414691 | ADTRP | Q96IZ2 | Androgen-dependent TFPI-regulating protein | chr6 | GO:0071383 | Not Cancer Driver | No | 41 | 0.178 | 2 | 0 | 0.0 | 0 |
| AIFM1 | AIFM1 | O95831 | Apoptosis-inducing factor 1, mitochondrial | chrX | GO:0071383 | Not Cancer Driver | No | 88 | 0.144 | 166 | 22 | 0.133 | 11 |
| AKR1C3 | AKR1C3 | P42330 | Aldo-keto reductase family 1 member C3 | chr10 | GO:0071383 | Not Cancer Driver | No | 49 | 0.152 | 11 | 1 | 0.091 | 0 |
| ANXA1_ENST00000257497 | ANXA1 | P04083 | Annexin A1 | chr9 | GO:0071383 | Not Cancer Driver | No | 59 | 0.171 | 61 | 12 | 0.197 | 0 |
| AQP1 | AQP1 | P29972 | Aquaporin-1 | chr7 | GO:0071383 | Not Cancer Driver | No | 39 | 0.145 | 4 | 1 | 0.25 | 0 |
| AR | AR | P10275 | Androgen receptor | chrX | GO:0071383 | Census, Compendium | Yes | 196 | 0.213 | 443 | 88 | 0.199 | 169 |
| ARG1_ENST00000368087 | ARG1 | P05089 | Arginase-1 | chr6 | GO:0071383 | Not Cancer Driver | No | 41 | 0.127 | 83 | 12 | 0.145 | 9 |
| ASS1_ENST00000352480 | ASS1 | P00966 | Argininosuccinate synthase | chr9 | GO:0071383 | Not Cancer Driver | No | 65 | 0.158 | 63 | 8 | 0.127 | 86 |
| ATP1A1_ENST00000295598 | ATP1A1 | P05023 | Sodium/potassium-transporting ATPase subunit alpha-1 | chr1 | GO:0071383 | Census | Yes | 115 | 0.112 | 115 | 16 | 0.139 | 6 |
| ATP1A2 | ATP1A2 | P50993 | Sodium/potassium-transporting ATPase subunit alpha-2 | chr1 | GO:0071383 | Not Cancer Driver | No | 230 | 0.225 | 161 | 34 | 0.211 | 8 |
| ATP1A3_ENST00000302102 | ATP1A3 | P13637 | Sodium/potassium-transporting ATPase subunit alpha-3 | chr19 | GO:0071383 | Not Cancer Driver | No | 200 | 0.197 | 115 | 29 | 0.252 | 31 |
| ATP2B1_ENST00000261173 | ATP2B1 | P20020 | Plasma membrane calcium-transporting ATPase 1 | chr12 | GO:0071383 | Not Cancer Driver | No | 143 | 0.117 | 293 | 42 | 0.143 | 0 |
| ATP5F1A_ENST00000282050 | ATP5F1A | P25705 | ATP synthase subunit alpha, mitochondrial | chr18 | GO:0071383 | Not Cancer Driver | No | 66 | 0.119 | 23 | 5 | 0.217 | 2 |
| BCL2L11 | BCL2L11 | O43521 | Bcl-2-like protein 11 | chr2 | GO:0071383 | Not Cancer Driver | No | 42 | 0.212 | 130 | 17 | 0.131 | 0 |
| CASP9 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0071383 | Census | Yes | 49 | 0.118 | 71 | 7 | 0.099 | 0 |
| CBX3_ENST00000396386 | CBX3 | Q13185 | Chromobox protein homolog 3 | chr7 | GO:0071383 | Not Cancer Driver | No | 23 | 0.126 | 119 | 18 | 0.151 | 0 |
| CFLAR | CFLAR | O15519 | CASP8 and FADD-like apoptosis regulator | chr2 | GO:0071383 | Not Cancer Driver | No | 40 | 0.083 | 44 | 2 | 0.045 | 0 |
| CYP1B1 | CYP1B1 | Q16678 | Cytochrome P450 1B1 | chr2 | GO:0071383 | Not Cancer Driver | No | 61 | 0.112 | 31 | 3 | 0.097 | 40 |
| DDIT4 | DDIT4 | Q9NX09 | DNA damage-inducible transcript 4 protein | chr10 | GO:0071383 | Not Cancer Driver | No | 20 | 0.086 | 87 | 9 | 0.103 | 0 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0071383 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| EIF4E_ENST00000450253 | EIF4E | P06730 | Eukaryotic translation initiation factor 4E | chr4 | GO:0071383 | Not Cancer Driver | No | 26 | 0.12 | 54 | 6 | 0.111 | 0 |
| ERRFI1 | ERRFI1 | Q9UJM3 | ERBB receptor feedback inhibitor 1 | chr1 | GO:0071383 | Not Cancer Driver | No | 55 | 0.119 | 297 | 37 | 0.125 | 0 |
| FAM107A_ENST00000394481 | FAM107A | O95990 | Actin-associated protein FAM107A | chr3 | GO:0071383 | Not Cancer Driver | No | 25 | 0.174 | 141 | 24 | 0.17 | 0 |
| FBXO32 | FBXO32 | Q969P5 | F-box only protein 32 | chr8 | GO:0071383 | Not Cancer Driver | No | 54 | 0.152 | 0 | 0 | 0.0 | 0 |
| FLT3 | FLT3 | P36888 | Receptor-type tyrosine-protein kinase FLT3 | chr13 | GO:0071383 | Census, Compendium | Yes | 200 | 0.201 | 64 | 27 | 0.422 | 0 |
| FOXO3 | FOXO3 | O43524 | Forkhead box protein O3 | chr6 | GO:0071383 | Census, Compendium | Yes | 70 | 0.104 | 595 | 68 | 0.114 | 0 |
| GJB2_ENST00000382848 | GJB2 | P29033 | Gap junction beta-2 protein | chr13 | GO:0071383 | Not Cancer Driver | No | 34 | 0.15 | 0 | 0 | 0.0 | 46 |
| GPER1 | GPER1 | Q99527 | G-protein coupled estrogen receptor 1 | chr7 | GO:0071383 | Not Cancer Driver | No | 65 | 0.173 | 13 | 5 | 0.385 | 0 |
| HMGCS2 | HMGCS2 | P54868 | Hydroxymethylglutaryl-CoA synthase, mitochondrial | chr1 | GO:0071383 | Not Cancer Driver | No | 92 | 0.181 | 29 | 4 | 0.138 | 19 |
| HNRNPU | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | GO:0071383 | Not Cancer Driver | No | 77 | 0.093 | 504 | 45 | 0.089 | 0 |
| HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | GO:0071383 | Not Cancer Driver | No | 24 | 0.037 | 200 | 13 | 0.065 | 0 |
| HSPA1B | HSPA1B | P0DMV9 | Heat shock 70 kDa protein 1B | chr6 | GO:0071383 | Not Cancer Driver | No | 15 | 0.023 | 200 | 5 | 0.025 | 0 |
| HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | GO:0071383 | Not Cancer Driver | No | 149 | 0.231 | 251 | 52 | 0.207 | 0 |
| IGF1R | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0071383 | Not Cancer Driver | No | 183 | 0.134 | 265 | 37 | 0.14 | 6 |
| ISL1 | ISL1 | P61371 | Insulin gene enhancer protein ISL-1 | chr5 | GO:0071383 | Not Cancer Driver | No | 85 | 0.244 | 180 | 41 | 0.228 | 0 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0071383 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
| KLF9 | KLF9 | Q13886 | Krueppel-like factor 9 | chr9 | GO:0071383 | Not Cancer Driver | No | 34 | 0.139 | 154 | 24 | 0.156 | 0 |
| MED1 | MED1 | Q15648 | Mediator of RNA polymerase II transcription subunit 1 | chr17 | GO:0071383 | Not Cancer Driver | No | 162 | 0.102 | 1104 | 117 | 0.106 | 0 |
| METTL21C | METTL21C | Q5VZV1 | Protein-lysine methyltransferase METTL21C | chr13 | GO:0071383 | Not Cancer Driver | No | 54 | 0.205 | 47 | 13 | 0.277 | 0 |
| MGARP | MGARP | Q8TDB4 | Protein MGARP | chr4 | GO:0071383 | Not Cancer Driver | No | 25 | 0.104 | 207 | 22 | 0.106 | 0 |
| MSTN | MSTN | O14793 | Growth/differentiation factor 8 | chr2 | GO:0071383 | Not Cancer Driver | No | 68 | 0.181 | 64 | 11 | 0.172 | 0 |
| MYOD1 | MYOD1 | P15172 | Myoblast determination protein 1 | chr11 | GO:0071383 | Census | Yes | 45 | 0.141 | 246 | 33 | 0.134 | 0 |
| NKX3-1 | NKX3-1 | Q99801 | Homeobox protein Nkx-3.1 | chr8 | GO:0071383 | Not Cancer Driver | No | 35 | 0.15 | 171 | 16 | 0.094 | 0 |
| NPAS4 | NPAS4 | Q8IUM7 | Neuronal PAS domain-containing protein 4 | chr11 | GO:0071383 | Not Cancer Driver | No | 229 | 0.286 | 429 | 114 | 0.266 | 0 |
| NPC1 | NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | chr18 | GO:0071383 | Not Cancer Driver | No | 155 | 0.121 | 24 | 0 | 0.0 | 150 |
| NR3C1_ENST00000343796 | NR3C1 | P04150 | Glucocorticoid receptor | chr5 | GO:0071383 | Not Cancer Driver | No | 92 | 0.118 | 362 | 37 | 0.102 | 12 |
| PCK1 | PCK1 | P35558 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | chr20 | GO:0071383 | Not Cancer Driver | No | 142 | 0.228 | 110 | 28 | 0.255 | 1 |
| PCK2 | PCK2 | Q16822 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | chr14 | GO:0071383 | Not Cancer Driver | No | 91 | 0.142 | 139 | 13 | 0.094 | 0 |
| PLAT | PLAT | P00750 | Tissue-type plasminogen activator | chr8 | GO:0071383 | Not Cancer Driver | No | 89 | 0.158 | 15 | 2 | 0.133 | 0 |
| RAN_ENST00000392369 | RAN | P62826 | GTP-binding nuclear protein Ran | chr12 | GO:0071383 | Not Cancer Driver | No | 20 | 0.093 | 14 | 1 | 0.071 | 0 |
| REST | REST | Q13127 | RE1-silencing transcription factor | chr4 | GO:0071383 | Not Cancer Driver | No | 142 | 0.129 | 868 | 113 | 0.13 | 4 |
| RPS6KB1 | RPS6KB1 | P23443 | Ribosomal protein S6 kinase beta-1 | chr17 | GO:0071383 | Not Cancer Driver | No | 45 | 0.086 | 226 | 26 | 0.115 | 0 |
| SERPINF1 | SERPINF1 | P36955 | Pigment epithelium-derived factor | chr17 | GO:0071383 | Not Cancer Driver | No | 51 | 0.122 | 57 | 5 | 0.088 | 0 |
| SGK1_ENST00000237305 | SGK1 | O00141 | Serine/threonine-protein kinase Sgk1 | chr6 | GO:0071383 | Census, Compendium | Yes | 58 | 0.135 | 86 | 16 | 0.186 | 0 |
| SMYD3 | SMYD3 | Q9H7B4 | Histone-lysine N-methyltransferase SMYD3 | chr1 | GO:0071383 | Not Cancer Driver | No | 59 | 0.138 | 2 | 0 | 0.0 | 0 |
| SOX10_ENST00000360880 | SOX10 | P56693 | Transcription factor SOX-10 | chr22 | GO:0071383 | Not Cancer Driver | No | 66 | 0.142 | 421 | 62 | 0.147 | 14 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0071383 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| SRD5A1 | SRD5A1 | P18405 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | chr5 | GO:0071383 | Not Cancer Driver | No | 35 | 0.135 | 0 | 0 | 0.0 | 0 |
| SSTR2 | SSTR2 | P30874 | Somatostatin receptor type 2 | chr17 | GO:0071383 | Not Cancer Driver | No | 54 | 0.146 | 22 | 7 | 0.318 | 0 |
| SSTR3 | SSTR3 | P32745 | Somatostatin receptor type 3 | chr22 | GO:0071383 | Not Cancer Driver | No | 94 | 0.225 | 110 | 26 | 0.236 | 0 |
| SSTR4 | SSTR4 | P31391 | Somatostatin receptor type 4 | chr20 | GO:0071383 | Not Cancer Driver | No | 129 | 0.332 | 39 | 12 | 0.308 | 0 |
| SSTR5 | SSTR5 | P35346 | Somatostatin receptor type 5 | chr16 | GO:0071383 | Not Cancer Driver | No | 60 | 0.165 | 45 | 12 | 0.267 | 0 |
| STC1 | STC1 | P52823 | Stanniocalcin-1 | chr8 | GO:0071383 | Not Cancer Driver | No | 59 | 0.239 | 58 | 12 | 0.207 | 0 |
| TFAP4 | TFAP4 | Q01664 | Transcription factor AP-4 | chr16 | GO:0071383 | Compendium | Yes | 61 | 0.18 | 285 | 52 | 0.182 | 0 |
| TFPI | TFPI | P10646 | Tissue factor pathway inhibitor | chr2 | GO:0071383 | Not Cancer Driver | No | 47 | 0.155 | 28 | 2 | 0.071 | 0 |
| TRERF1_ENST00000372922 | TRERF1 | Q96PN7 | Transcriptional-regulating factor 1 | chr6 | GO:0071383 | Not Cancer Driver | No | 226 | 0.188 | 957 | 167 | 0.175 | 0 |
| UBE2L3_ENST00000342192 | UBE2L3 | P68036 | Ubiquitin-conjugating enzyme E2 L3 | chr22 | GO:0071383 | Not Cancer Driver | No | 19 | 0.123 | 32 | 4 | 0.125 | 0 |
| UGT1A1 | UGT1A1 | P22309 | UDP-glucuronosyltransferase 1A1 | chr2 | GO:0071383 | Not Cancer Driver | No | 100 | 0.188 | 11 | 2 | 0.182 | 55 |
| URI1 | URI1 | O94763 | Unconventional prefoldin RPB5 interactor 1 | chr19 | GO:0071383 | Not Cancer Driver | No | 88 | 0.164 | 388 | 64 | 0.165 | 0 |
| USP8 | USP8 | P40818 | Ubiquitin carboxyl-terminal hydrolase 8 | chr15 | GO:0071383 | Census, Compendium | Yes | 122 | 0.109 | 602 | 69 | 0.115 | 0 |
| ZFP36 | ZFP36 | P26651 | mRNA decay activator protein ZFP36 | chr19 | GO:0071383 | Not Cancer Driver | No | 43 | 0.132 | 262 | 34 | 0.13 | 0 |
| ZFP36L1 | ZFP36L1 | Q07352 | mRNA decay activator protein ZFP36L1 | chr14 | GO:0071383 | Compendium | Yes | 57 | 0.169 | 212 | 30 | 0.142 | 0 |
| ZFP36L2 | ZFP36L2 | P47974 | mRNA decay activator protein ZFP36L2 | chr2 | GO:0071383 | Not Cancer Driver | No | 73 | 0.148 | 324 | 45 | 0.139 | 0 |